CAK95_RS06000 510d795745049e694c236e338e8ca0bd 498 Pfam PF00171 Aldehyde dehydrogenase family 29 490 3.1E-150 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS06000 510d795745049e694c236e338e8ca0bd 498 SUPERFAMILY SSF53720 13 493 1.83E-153 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS06000 510d795745049e694c236e338e8ca0bd 498 Gene3D G3DSA:3.40.309.10 276 455 1.5E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS06000 510d795745049e694c236e338e8ca0bd 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS06000 510d795745049e694c236e338e8ca0bd 498 Gene3D G3DSA:3.40.605.10 21 275 1.5E-85 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS20765 bf538f98cb6bc3b2c85bc9c51d4b8864 202 Gene3D G3DSA:2.30.110.10 10 187 5.3E-63 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS20765 bf538f98cb6bc3b2c85bc9c51d4b8864 202 SUPERFAMILY SSF50475 8 194 2.31E-47 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS20765 bf538f98cb6bc3b2c85bc9c51d4b8864 202 Pfam PF01613 Flavin reductase like domain 23 163 7.7E-18 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS20765 bf538f98cb6bc3b2c85bc9c51d4b8864 202 SMART SM00903 19 166 1.1E-14 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 Gene3D G3DSA:3.40.50.300 1 208 3.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 176 3.3E-36 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 211 24.331 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 PIRSF PIRSF006755 1 224 4.6E-43 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 Pfam PF13500 AAA domain 3 203 1.1E-33 T 06-07-2017 CAK95_RS12830 bcb1cafb0cf54a48268b3cf837d3c2e8 227 SUPERFAMILY SSF52540 1 208 9.74E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 Gene3D G3DSA:3.40.50.10410 105 194 3.2E-18 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 SUPERFAMILY SSF56784 30 251 1.32E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 Gene3D G3DSA:3.40.50.1000 29 100 8.7E-25 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 Gene3D G3DSA:3.40.50.1000 199 251 8.7E-25 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 Pfam PF13344 Haloacid dehalogenase-like hydrolase 31 126 1.1E-14 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK95_RS00970 38792824cb88dd3ebc4bd6bd6b16996c 274 Pfam PF13242 HAD-hyrolase-like 200 250 3.1E-10 T 06-07-2017 CAK95_RS09650 b0b25613ab245bd263a2cfd3e9992ec7 393 SUPERFAMILY SSF53822 24 392 6.77E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS09650 b0b25613ab245bd263a2cfd3e9992ec7 393 Pfam PF13458 Periplasmic binding protein 24 362 4.5E-71 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS09650 b0b25613ab245bd263a2cfd3e9992ec7 393 Gene3D G3DSA:3.40.50.2300 296 348 3.5E-38 T 06-07-2017 CAK95_RS09650 b0b25613ab245bd263a2cfd3e9992ec7 393 Gene3D G3DSA:3.40.50.2300 20 147 3.5E-38 T 06-07-2017 CAK95_RS09650 b0b25613ab245bd263a2cfd3e9992ec7 393 Gene3D G3DSA:3.40.50.2300 148 295 5.4E-23 T 06-07-2017 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 SUPERFAMILY SSF55961 130 303 8.24E-37 T 06-07-2017 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 SUPERFAMILY SSF55961 332 415 8.24E-37 T 06-07-2017 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 SUPERFAMILY SSF50022 17 138 3.54E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 Gene3D G3DSA:2.102.10.10 24 141 2.1E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 70 92 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAK95_RS05910 23cbe5edc3ff3150a17fc36af48058bf 428 Pfam PF00355 Rieske [2Fe-2S] domain 26 110 7.6E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS14350 a9213633c7b07f9f056c317dcc4e5d1b 400 Gene3D G3DSA:1.10.443.10 216 372 3.5E-20 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS14350 a9213633c7b07f9f056c317dcc4e5d1b 400 Pfam PF13356 Domain of unknown function (DUF4102) 3 87 1.8E-18 T 06-07-2017 IPR025166 Domain of unknown function DUF4102 CAK95_RS14350 a9213633c7b07f9f056c317dcc4e5d1b 400 Gene3D G3DSA:1.10.150.130 98 195 2.3E-20 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS14350 a9213633c7b07f9f056c317dcc4e5d1b 400 SUPERFAMILY SSF56349 98 383 1.53E-56 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS14350 a9213633c7b07f9f056c317dcc4e5d1b 400 Pfam PF00589 Phage integrase family 218 371 2.0E-15 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SUPERFAMILY SSF81923 4 143 2.49E-57 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SUPERFAMILY SSF52540 445 741 2.35E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Gene3D G3DSA:1.10.8.60 673 747 1.1E-28 T 06-07-2017 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SMART SM01086 661 753 4.2E-32 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SUPERFAMILY SSF52540 175 434 6.13E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 661 741 2.9E-23 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Pfam PF07724 AAA domain (Cdc48 subfamily) 495 654 9.1E-45 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 526 544 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Gene3D G3DSA:3.40.50.300 177 358 2.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 5 742 0.0 T 06-07-2017 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 570 588 2.7E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 499 517 2.7E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 617 2.7E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 2.7E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SMART SM00382 214 359 2.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 SMART SM00382 495 658 8.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 64 2.0E-13 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Gene3D G3DSA:1.10.8.60 360 443 1.2E-28 T 06-07-2017 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Gene3D G3DSA:3.40.50.300 450 672 1.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Gene3D G3DSA:1.10.1780.10 4 143 1.2E-40 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 350 1.1E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS21955 d3dd0ed75f71d3d0e6262327ebb8ca6b 816 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 310 322 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 202 6.3E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SMART SM00388 137 202 3.3E-25 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SUPERFAMILY SSF47384 123 203 6.67E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SMART SM00387 249 361 1.1E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SUPERFAMILY SSF52172 514 638 5.12E-33 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Gene3D G3DSA:3.40.50.2300 375 488 4.6E-7 T 06-07-2017 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Pfam PF00072 Response regulator receiver domain 518 637 2.4E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Gene3D G3DSA:1.10.287.130 129 198 2.9E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SMART SM00448 379 487 0.15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SMART SM00448 516 637 1.1E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SUPERFAMILY SSF52172 376 488 3.13E-9 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 359 1.3E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 3.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 3.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 315 3.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 3.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 SUPERFAMILY SSF55874 192 364 6.29E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Gene3D G3DSA:3.40.50.2300 513 638 1.6E-34 T 06-07-2017 CAK95_RS08820 a71ee8ff9864b939ce38ea470c29c8cf 646 Gene3D G3DSA:3.30.565.10 203 367 2.2E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 Pfam PF01339 CheB methylesterase 178 357 1.3E-53 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 Pfam PF00072 Response regulator receiver domain 1 105 2.2E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 362 31.955 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 SUPERFAMILY SSF52738 173 361 1.02E-60 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 PIRSF PIRSF000876 1 366 3.1E-111 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 SMART SM00448 1 113 2.6E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 Gene3D G3DSA:3.40.50.2300 1 106 2.5E-25 T 06-07-2017 CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 SUPERFAMILY SSF52172 1 105 4.27E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS15155 bd9c7e954f7532196fe6c67b872a47f8 366 Gene3D G3DSA:3.40.50.180 171 362 2.2E-66 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS09780 2b57675bcd9a03994d9124edbfc2d2a7 596 Gene3D G3DSA:1.50.10.10 217 589 6.9E-74 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK95_RS09780 2b57675bcd9a03994d9124edbfc2d2a7 596 Pfam PF00723 Glycosyl hydrolases family 15 219 523 2.0E-28 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK95_RS09780 2b57675bcd9a03994d9124edbfc2d2a7 596 SUPERFAMILY SSF48208 204 589 9.87E-84 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK95_RS04265 fc82f0b3084087677854238714d10401 149 Pfam PF00075 RNase H 6 142 1.7E-49 T 06-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CAK95_RS04265 fc82f0b3084087677854238714d10401 149 Gene3D G3DSA:3.30.420.10 5 143 6.4E-59 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS04265 fc82f0b3084087677854238714d10401 149 Hamap MF_00042 Ribonuclease H [rnhA]. 3 148 34.257 T 06-07-2017 IPR022892 Ribonuclease H GO:0004523 CAK95_RS04265 fc82f0b3084087677854238714d10401 149 SUPERFAMILY SSF53098 4 142 1.26E-57 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Gene3D G3DSA:1.10.287.130 354 412 4.4E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Gene3D G3DSA:3.30.565.10 413 594 1.7E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SUPERFAMILY SSF47384 348 424 3.73E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 535 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 549 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SUPERFAMILY SSF52172 619 736 2.13E-22 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Pfam PF02743 Cache domain 53 288 3.7E-14 T 06-07-2017 IPR033479 Double Cache domain 1 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Gene3D G3DSA:3.40.50.2300 618 736 7.8E-29 T 06-07-2017 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Pfam PF00512 His Kinase A (phospho-acceptor) domain 361 424 3.2E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SMART SM00448 618 731 4.1E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 589 2.8E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SMART SM00387 468 592 1.9E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SUPERFAMILY SSF55874 418 593 3.27E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Pfam PF00072 Response regulator receiver domain 620 731 2.8E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 Gene3D G3DSA:3.30.450.20 107 201 3.7E-9 T 06-07-2017 CAK95_RS20035 c582b9b5624c7b1cf4a3c2b089e3565c 763 SMART SM00388 360 427 4.3E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 Pfam PF02195 ParB-like nuclease domain 10 79 1.3E-10 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 Gene3D G3DSA:3.90.1530.10 5 92 7.4E-15 T 06-07-2017 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 SMART SM00470 7 93 4.2E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 Pfam PF01555 DNA methylase 193 403 4.2E-29 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 195 201 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 SUPERFAMILY SSF53335 160 408 8.11E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 Gene3D G3DSA:3.40.50.150 159 415 1.1E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 SUPERFAMILY SSF110849 6 105 4.36E-22 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 PIRSF PIRSF036758 4 425 1.2E-99 T 06-07-2017 IPR015840 DNA methyase, ParB domain-containing CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 192 204 4.2E-16 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 346 368 4.2E-16 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 369 383 4.2E-16 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CAK95_RS27045 d9a43b6654f72d08aa9b844f2d3d35ee 445 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 239 258 4.2E-16 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CAK95_RS10890 6edd264f6063b8c7bf33863919f84375 141 SUPERFAMILY SSF49764 32 137 1.99E-16 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS10890 6edd264f6063b8c7bf33863919f84375 141 Gene3D G3DSA:2.60.40.790 45 137 6.4E-12 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS10890 6edd264f6063b8c7bf33863919f84375 141 Pfam PF00011 Hsp20/alpha crystallin family 46 137 1.6E-15 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAK95_RS10755 af0f0019da5a9c753ff32243e51737b1 350 Pfam PF00535 Glycosyl transferase family 2 17 141 6.0E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS10755 af0f0019da5a9c753ff32243e51737b1 350 Gene3D G3DSA:3.90.550.10 14 229 1.9E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS10755 af0f0019da5a9c753ff32243e51737b1 350 SUPERFAMILY SSF53448 14 235 5.56E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 Gene3D G3DSA:1.50.10.20 39 306 7.2E-63 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 19 307 3.8E-115 T 06-07-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 10 641 2.1E-227 T 06-07-2017 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 316 638 1.1E-149 T 06-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 Gene3D G3DSA:1.50.10.20 307 639 2.8E-114 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 SUPERFAMILY SSF48239 246 267 1.88E-104 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 SUPERFAMILY SSF48239 312 639 1.88E-104 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 SUPERFAMILY SSF48239 42 312 1.57E-73 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 18 638 3.4E-186 T 06-07-2017 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAK95_RS04495 601bdbca2e7744eca49c9d07742c4f33 651 ProSitePatterns PS01074 Terpene synthases signature. 493 507 - T 06-07-2017 IPR002365 Terpene synthase, conserved site GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAK95_RS09240 617ab1e4c07819180db653662014aa82 226 Pfam PF00814 Glycoprotease family 32 137 1.8E-28 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS09240 617ab1e4c07819180db653662014aa82 226 SUPERFAMILY SSF53067 1 103 6.47E-27 T 06-07-2017 CAK95_RS09240 617ab1e4c07819180db653662014aa82 226 Gene3D G3DSA:3.30.420.40 1 134 1.2E-39 T 06-07-2017 CAK95_RS09240 617ab1e4c07819180db653662014aa82 226 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 211 5.7E-49 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 SMART SM00345 10 68 4.2E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 1.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 SMART SM00895 78 202 6.6E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 SUPERFAMILY SSF46785 9 97 2.73E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 Gene3D G3DSA:1.20.120.530 72 213 1.4E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 SUPERFAMILY SSF48008 75 210 6.28E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 Gene3D G3DSA:1.10.10.10 9 69 3.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17280 1033dff01a41d7bea8d8ab81320881b0 219 Pfam PF07729 FCD domain 78 201 1.6E-30 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 293 4.3E-124 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 PIRSF PIRSF000103 1 295 1.1E-86 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 SUPERFAMILY SSF48179 163 293 1.25E-41 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 Gene3D G3DSA:3.40.50.720 2 163 2.3E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 2.3E-49 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 292 2.3E-40 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 Gene3D G3DSA:1.10.1040.10 164 293 2.7E-46 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS22415 9e9848c387d2c2c2bef6a3d38f9efb21 295 SUPERFAMILY SSF51735 3 162 6.09E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Gene3D G3DSA:3.40.50.80 95 238 4.6E-40 T 06-07-2017 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 358 6.5E-139 T 06-07-2017 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Pfam PF00970 Oxidoreductase FAD-binding domain 9 104 6.2E-13 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 SUPERFAMILY SSF63380 4 104 1.42E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Gene3D G3DSA:3.10.20.30 239 359 3.0E-30 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 274 348 3.2E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Pfam PF00175 Oxidoreductase NAD-binding domain 119 227 3.1E-19 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 SUPERFAMILY SSF54292 236 357 1.03E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 Gene3D G3DSA:2.40.30.10 4 94 8.2E-24 T 06-07-2017 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 37 47 6.5E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 151 6.5E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 6.5E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 117 136 6.5E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 165 6.5E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00406 Cytochrome B5 reductase signature 92 106 6.1E-8 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00406 Cytochrome B5 reductase signature 213 221 6.1E-8 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00406 Cytochrome B5 reductase signature 117 136 6.1E-8 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 PRINTS PR00406 Cytochrome B5 reductase signature 154 165 6.1E-8 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17385 116bcfaa6761bbc1df6cfe7a10f51480 360 SUPERFAMILY SSF52343 95 243 3.93E-36 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 423 445 8.0E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 269 291 8.0E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 8.0E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 Pfam PF00361 Proton-conducting membrane transporter 130 420 5.4E-93 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 637 5.2E-266 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 251 277 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 424 443 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 250 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 8.1E-68 T 06-07-2017 CAK95_RS22885 919181ed263849badb73cdb779b51307 642 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 118 2.4E-27 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Gene3D G3DSA:3.40.50.620 284 325 3.1E-4 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Pfam PF01921 tRNA synthetases class I (K) 18 371 8.5E-130 T 06-07-2017 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 28 529 6.5E-51 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 17 538 29.513 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 SUPERFAMILY SSF48163 335 538 1.01E-40 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Gene3D G3DSA:1.10.10.350 432 538 5.2E-30 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 SUPERFAMILY SSF52374 18 336 2.0E-56 T 06-07-2017 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 56 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Gene3D G3DSA:3.40.50.620 19 199 7.6E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS05675 ee93ca8f62f277d0dce4a1442a6b2956 542 Gene3D G3DSA:3.40.50.620 237 283 7.6E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS12840 515ad410df8c7193248af1b4850ddc38 115 Pfam PF02641 Uncharacterized ACR, COG1993 9 104 1.3E-40 T 06-07-2017 IPR003793 Domain of unknown function DUF190 CAK95_RS12840 515ad410df8c7193248af1b4850ddc38 115 Gene3D G3DSA:3.30.70.120 1 112 2.7E-44 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK95_RS12840 515ad410df8c7193248af1b4850ddc38 115 SUPERFAMILY SSF54913 6 105 3.22E-34 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 Pfam PF00920 Dehydratase family 41 558 2.2E-206 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 SUPERFAMILY SSF52016 383 561 1.49E-57 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 SUPERFAMILY SSF143975 7 382 2.48E-134 T 06-07-2017 CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 129 139 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 11 561 45.193 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 24 560 4.0E-207 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS24025 99e600305c9d2754d0d9ce3c80472f67 574 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 469 480 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS13400 a1c9002035a9b7b759c8a5b4b83707e9 337 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 15 298 4.9E-57 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAK95_RS13400 a1c9002035a9b7b759c8a5b4b83707e9 337 Gene3D G3DSA:3.40.50.300 52 107 7.5E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13400 a1c9002035a9b7b759c8a5b4b83707e9 337 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 2 336 33.62 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAK95_RS13400 a1c9002035a9b7b759c8a5b4b83707e9 337 SUPERFAMILY SSF52540 42 144 7.68E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13400 a1c9002035a9b7b759c8a5b4b83707e9 337 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 15 329 1.1E-86 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 SMART SM00347 3 103 2.8E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 Pfam PF01047 MarR family 13 67 5.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 Gene3D G3DSA:1.10.10.10 2 117 2.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 113 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 59 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 27 43 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02230 12208b03b6aa95eb3b047b9f253205c8 134 SUPERFAMILY SSF46785 2 117 7.91E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 SUPERFAMILY SSF53335 167 437 6.5E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 Pfam PF01555 DNA methylase 200 426 1.8E-18 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 SUPERFAMILY SSF110849 9 129 5.23E-32 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 Gene3D G3DSA:3.90.1530.10 6 95 1.3E-17 T 06-07-2017 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 Pfam PF02195 ParB-like nuclease domain 13 82 2.4E-11 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 388 406 1.3E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 198 212 1.3E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 369 386 1.3E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 411 431 1.3E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 SMART SM00470 10 96 1.4E-14 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 Gene3D G3DSA:3.40.50.150 348 437 3.9E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 Gene3D G3DSA:3.40.50.150 165 316 3.9E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03075 3dbe950141c1443c7019c005848052f2 463 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 203 208 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 Gene3D G3DSA:1.10.8.10 21 98 9.1E-24 T 06-07-2017 CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 19 294 5.2E-58 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 16 297 40.106 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 Gene3D G3DSA:3.40.50.150 101 297 8.2E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 38 293 3.6E-77 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 Pfam PF13847 Methyltransferase domain 131 258 1.1E-10 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 SUPERFAMILY SSF53335 16 293 1.63E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10380 edd6a5a548baafaab9918a3404a37d31 299 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 200 206 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK95_RS08690 c5af82f506916ec688174dbcdf50756d 169 Gene3D G3DSA:3.40.630.30 6 167 7.9E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08690 c5af82f506916ec688174dbcdf50756d 169 Pfam PF00583 Acetyltransferase (GNAT) family 67 144 1.3E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS08690 c5af82f506916ec688174dbcdf50756d 169 SUPERFAMILY SSF55729 1 149 4.71E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 Gene3D G3DSA:1.10.10.60 12 56 5.6E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 Gene3D G3DSA:1.10.357.10 80 204 7.9E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 9.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 SUPERFAMILY SSF46689 13 97 1.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 SUPERFAMILY SSF48498 94 218 2.7E-36 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS17180 a373f39e98fb5d959841e58ae40100f1 219 Gene3D G3DSA:1.10.10.60 57 79 5.5E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.50.720 2106 2281 7.0E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 259 1.5E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.90.180.10 1781 1907 1.7E-42 T 06-07-2017 IPR011032 GroES-like CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 834 9.8E-86 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.366.10 533 655 1.9E-65 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.366.10 724 832 1.9E-65 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00829 1770 2083 5.6E-162 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00825 Beta-ketoacyl synthase 14 438 6.2E-181 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:1.10.1200.10 2386 2461 1.6E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.47.10 275 437 1.6E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.50.720 1908 2002 5.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00826 898 1054 6.8E-29 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF50129 1774 1904 2.83E-29 T 06-07-2017 IPR011032 GroES-like CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 492 2.8E-19 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF08659 KR domain 2104 2282 5.9E-61 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF55048 661 724 1.23E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF00107 Zinc-binding dehydrogenase 1914 2022 6.4E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1903 1924 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF51735 2106 2319 1.17E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF51735 1878 2050 1.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.50.150 1365 1530 4.3E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF53901 413 434 1.82E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF53901 9 378 1.82E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00823 Phosphopantetheine attachment site 2390 2461 2.3E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF00698 Acyl transferase domain 535 836 1.6E-58 T 06-07-2017 IPR014043 Acyl transferase CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1788 1852 3.3E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2104 2284 3.5E-50 T 06-07-2017 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF53335 1366 1531 1.42E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2416 2431 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.30.70.250 659 722 3.6E-5 T 06-07-2017 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF14765 Polyketide synthase dehydratase 898 1168 1.8E-51 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF51735 1557 1746 5.63E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Gene3D G3DSA:3.40.47.10 10 271 6.8E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 274 385 4.4E-36 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF52151 726 821 2.62E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF52151 533 661 2.62E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 SUPERFAMILY SSF47336 2389 2480 2.49E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS26810 b97a85c191552d329335f1a05575b6f6 2510 Pfam PF00550 Phosphopantetheine attachment site 2395 2456 6.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS15700 42af04161b2ca032111aa7fddec15907 295 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 194 268 3.0E-8 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK95_RS15700 42af04161b2ca032111aa7fddec15907 295 SUPERFAMILY SSF103025 5 210 3.14E-55 T 06-07-2017 CAK95_RS15700 42af04161b2ca032111aa7fddec15907 295 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 154 218 6.9E-24 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site CAK95_RS15700 42af04161b2ca032111aa7fddec15907 295 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 97 9.8E-10 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK95_RS15700 42af04161b2ca032111aa7fddec15907 295 Gene3D G3DSA:3.30.70.1400 9 97 1.2E-24 T 06-07-2017 CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 SUPERFAMILY SSF52540 186 370 9.77E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 SUPERFAMILY SSF52540 490 635 7.01E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 SUPERFAMILY SSF52540 212 262 7.01E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 721 23.792 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Gene3D G3DSA:3.40.50.300 488 628 6.7E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Gene3D G3DSA:3.40.50.300 401 422 6.7E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 TIGRFAM TIGR00595 priA: primosomal protein N' 213 718 1.3E-185 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Pfam PF00270 DEAD/DEAH box helicase 196 352 8.4E-15 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Pfam PF00271 Helicase conserved C-terminal domain 517 582 2.7E-5 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 SMART SM00490 487 584 1.1E-4 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 SMART SM00487 186 384 4.3E-18 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS07440 720dc578ef8a632a8c759ee0fe35380f 722 Gene3D G3DSA:3.40.50.300 188 374 1.8E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 Pfam PF12833 Helix-turn-helix domain 203 281 1.8E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 Gene3D G3DSA:1.10.10.60 236 283 1.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 SUPERFAMILY SSF46689 180 228 3.85E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 2.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 2.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 Gene3D G3DSA:1.10.10.60 177 235 7.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 SUPERFAMILY SSF46689 233 283 8.06E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07240 077cbee4e93eccecc01be85ed1a69410 289 SMART SM00342 197 280 5.3E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 Gene3D G3DSA:3.40.50.720 4 254 2.1E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 SUPERFAMILY SSF51735 7 254 2.03E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17945 54b9c568afe3690c9c80e3539be340e1 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 254 4.1E-39 T 06-07-2017 CAK95_RS04790 a1c5a7f0bb36908879ca466908382515 331 SUPERFAMILY SSF53850 44 259 2.53E-32 T 06-07-2017 CAK95_RS04790 a1c5a7f0bb36908879ca466908382515 331 Gene3D G3DSA:3.40.190.10 59 132 6.5E-6 T 06-07-2017 CAK95_RS04790 a1c5a7f0bb36908879ca466908382515 331 Gene3D G3DSA:3.40.190.10 133 248 3.2E-17 T 06-07-2017 CAK95_RS04790 a1c5a7f0bb36908879ca466908382515 331 Pfam PF09084 NMT1/THI5 like 62 257 1.2E-16 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 SUPERFAMILY SSF53850 205 405 2.9E-25 T 06-07-2017 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Gene3D G3DSA:1.10.10.10 15 94 1.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Gene3D G3DSA:1.10.10.10 116 196 7.9E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Gene3D G3DSA:3.40.190.10 203 284 8.3E-11 T 06-07-2017 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 116 172 7.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 74 4.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 SUPERFAMILY SSF46785 116 193 1.17E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Pfam PF03466 LysR substrate binding domain 205 391 4.6E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 SUPERFAMILY SSF46785 9 95 5.12E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15635 39c1714b91d4d9976d0b51c84e9a09bb 413 Gene3D G3DSA:3.40.190.10 285 373 2.8E-10 T 06-07-2017 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Pfam PF01751 Toprim domain 432 532 6.8E-19 T 06-07-2017 IPR006171 Toprim domain CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 281 294 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 537 549 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 81 94 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 46 61 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 124 138 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 433 447 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 742 758 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 517 534 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR00418 DNA topoisomerase II family signature 499 515 4.3E-71 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 184 1.3E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SMART SM00433 46 803 3.4E-269 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 738 799 4.2E-26 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SUPERFAMILY SSF56719 407 572 2.43E-84 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SUPERFAMILY SSF56719 736 804 2.43E-84 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SUPERFAMILY SSF54211 234 404 1.9E-59 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 809 100.736 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Gene3D G3DSA:3.40.50.670 727 791 2.2E-91 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Gene3D G3DSA:3.40.50.670 417 562 2.2E-91 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Gene3D G3DSA:3.30.565.10 26 226 2.0E-90 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SMART SM00387 42 187 3.4E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Pfam PF00204 DNA gyrase B 234 403 6.1E-57 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 SUPERFAMILY SSF55874 16 224 2.88E-72 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 192 207 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 779 795 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 207 220 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 373 387 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 325 341 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 763 775 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 387 407 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 483 492 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 233 255 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 PRINTS PR01159 DNA gyrase subunit B signature 16 26 7.3E-68 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 Gene3D G3DSA:3.30.230.10 233 405 1.3E-73 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS09435 efdfe17cc390e241d411e7aaa9be12e5 809 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 804 4.3E-298 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 SMART SM00382 209 393 6.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 Gene3D G3DSA:3.30.230.10 5 167 8.7E-28 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 404 502 1.2E-29 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 396 1.0E-92 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 9 502 1.5E-155 T 06-07-2017 IPR004482 Mg chelatase-related protein CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 139 8.7E-41 T 06-07-2017 CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 208 223 2.9E-5 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 288 302 2.9E-5 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 316 329 2.9E-5 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 Gene3D G3DSA:3.40.50.300 191 390 8.4E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 SUPERFAMILY SSF52540 192 503 2.46E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08825 168f3bfc299a3653c26e9929c8f05ad4 512 SUPERFAMILY SSF54211 8 169 8.34E-31 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 Gene3D G3DSA:3.40.50.2300 5 132 1.6E-29 T 06-07-2017 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 SMART SM00448 6 120 4.4E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 3.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 Gene3D G3DSA:1.10.10.10 149 210 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 Pfam PF00072 Response regulator receiver domain 9 120 2.1E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 SUPERFAMILY SSF46894 142 210 1.97E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 SMART SM00421 151 208 6.0E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 SUPERFAMILY SSF52172 6 132 2.13E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 7.0E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 7.0E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS05565 0ba8c8f55351805131a9101b39b2a0ac 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 7.0E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24915 6f39799e0f85de8f15b9a94641417991 461 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 445 2.2E-216 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK95_RS24915 6f39799e0f85de8f15b9a94641417991 461 Gene3D G3DSA:3.20.20.70 143 444 2.4E-160 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS24915 6f39799e0f85de8f15b9a94641417991 461 Gene3D G3DSA:1.10.220.70 55 141 2.6E-35 T 06-07-2017 CAK95_RS24915 6f39799e0f85de8f15b9a94641417991 461 PIRSF PIRSF018788 1 453 1.5E-231 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK95_RS24915 6f39799e0f85de8f15b9a94641417991 461 Gene3D G3DSA:2.30.170.30 2 54 4.5E-25 T 06-07-2017 CAK95_RS17370 96fb5e71fd4117404e681e53c7b91608 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 7 95 9.1E-41 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAK95_RS17370 96fb5e71fd4117404e681e53c7b91608 95 Pfam PF06243 Phenylacetic acid degradation B 6 92 1.8E-38 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAK95_RS17370 96fb5e71fd4117404e681e53c7b91608 95 PIRSF PIRSF030200 1 95 4.8E-42 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 Gene3D G3DSA:3.30.70.920 65 141 9.2E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 SUPERFAMILY SSF46785 9 67 6.93E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 SUPERFAMILY SSF54909 70 149 1.15E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.2E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.2E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.2E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 Gene3D G3DSA:1.10.10.10 8 60 3.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 3.2E-16 T 06-07-2017 CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 Pfam PF01037 Lrp/AsnC ligand binding domain 82 147 4.6E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS21480 b86af0f6a59c1a183c40e982e5036ebd 165 SMART SM00344 9 116 9.5E-31 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS14135 c95dfb0e5033cfaf2a162770e6458611 396 Gene3D G3DSA:1.10.443.10 168 373 1.6E-16 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS14135 c95dfb0e5033cfaf2a162770e6458611 396 Pfam PF00589 Phage integrase family 299 359 3.2E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS14135 c95dfb0e5033cfaf2a162770e6458611 396 SUPERFAMILY SSF56349 242 369 1.03E-18 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS15100 3fd073e247692f3c2f126be09147a9eb 234 SUPERFAMILY SSF52540 4 226 5.98E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15100 3fd073e247692f3c2f126be09147a9eb 234 SMART SM00382 29 209 6.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15100 3fd073e247692f3c2f126be09147a9eb 234 Gene3D G3DSA:3.40.50.300 3 225 5.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15100 3fd073e247692f3c2f126be09147a9eb 234 Pfam PF00005 ABC transporter 20 159 2.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15100 3fd073e247692f3c2f126be09147a9eb 234 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 Gene3D G3DSA:3.40.50.2300 6 125 3.0E-40 T 06-07-2017 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 Gene3D G3DSA:1.10.10.10 136 235 9.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 3.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 SUPERFAMILY SSF46894 131 232 8.5E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 SMART SM00448 6 117 1.8E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 SUPERFAMILY SSF52172 7 126 3.84E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 SMART SM00862 156 231 1.5E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS01260 78a4de2c4e550f338bbcac962e6bafff 242 Pfam PF00072 Response regulator receiver domain 8 118 6.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 SMART SM00418 6 85 5.0E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 9.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 9.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 9.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 Gene3D G3DSA:1.10.10.10 2 105 4.5E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 Pfam PF12840 Helix-turn-helix domain 7 65 2.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21460 5b1e014660bbcafb68669066da903cd3 107 SUPERFAMILY SSF46785 3 105 2.11E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 TIGRFAM TIGR01083 nth: endonuclease III 61 250 4.0E-82 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 SMART SM00478 94 241 1.3E-54 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 243 259 8.3E-5 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Gene3D G3DSA:1.10.340.30 79 178 9.9E-33 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 ProSitePatterns PS01155 Endonuclease III family signature. 158 187 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 SUPERFAMILY SSF48150 62 262 1.05E-69 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 SMART SM00525 242 262 0.0015 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 243 259 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Hamap MF_00942 Endonuclease III [nth]. 50 265 36.697 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Pfam PF00633 Helix-hairpin-helix motif 156 183 1.8E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 90 223 2.4E-20 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS08970 8fe953288ae04e9064ccf86be812f046 268 Gene3D G3DSA:1.10.1670.10 179 264 2.3E-35 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 SUPERFAMILY SSF117916 102 185 3.49E-27 T 06-07-2017 CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 87 1.0E-29 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 Pfam PF01106 NifU-like domain 117 182 4.3E-27 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 SMART SM00932 3 87 5.2E-46 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 SUPERFAMILY SSF110836 1 89 1.31E-30 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 Gene3D G3DSA:3.30.1370.70 1 89 5.7E-31 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 185 1.0E-26 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CAK95_RS09245 db576107c1b1a2fd50634bb40267d33d 185 PIRSF PIRSF036773 1 185 2.2E-70 T 06-07-2017 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 139 1.2E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 148 262 5.2E-11 T 06-07-2017 IPR000014 PAS domain CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 Gene3D G3DSA:1.10.260.40 277 312 1.7E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SUPERFAMILY SSF47413 276 317 5.25E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SMART SM00091 148 213 8.8E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SMART SM00091 21 89 110.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 Gene3D G3DSA:3.30.450.20 146 258 1.8E-23 T 06-07-2017 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 Gene3D G3DSA:3.30.450.20 23 134 1.6E-18 T 06-07-2017 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SMART SM00086 219 261 6.9E-7 T 06-07-2017 IPR001610 PAC motif CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SMART SM00086 94 136 6.1E-6 T 06-07-2017 IPR001610 PAC motif CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SUPERFAMILY SSF55785 30 138 1.2E-15 T 06-07-2017 IPR000014 PAS domain CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 Pfam PF08447 PAS fold 175 253 1.6E-17 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 Pfam PF08447 PAS fold 44 129 2.3E-14 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS23835 4ef12747f52bc82c846ab5db1b0169b1 350 SUPERFAMILY SSF55785 156 262 1.57E-19 T 06-07-2017 IPR000014 PAS domain CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 SUPERFAMILY SSF81296 338 453 2.8E-29 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 Gene3D G3DSA:3.90.420.10 92 309 1.3E-65 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 Pfam PF00174 Oxidoreductase molybdopterin binding domain 134 306 3.4E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 30 57 1.6E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 SUPERFAMILY SSF56524 90 308 1.29E-61 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 Gene3D G3DSA:2.60.40.650 338 452 7.7E-30 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 336 451 8.3E-16 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 199 214 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 254 270 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 100 114 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 120 136 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 287 300 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 375 387 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 271 284 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS07770 d3b5b9b6857c3c7f62e65b41f424f0a1 454 PRINTS PR00407 Eukaryotic molybdopterin domain signature 335 347 3.4E-20 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 Gene3D G3DSA:3.40.50.720 4 250 2.8E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 SUPERFAMILY SSF51735 10 250 3.74E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 8.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 8.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 4.5E-61 T 06-07-2017 CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01565 95bdddaee012e01c8860ae66acfdc0c8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.3E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 PIRSF PIRSF037307 5 853 5.0E-208 T 06-07-2017 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 Gene3D G3DSA:3.40.50.300 16 210 3.1E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 SMART SM00487 24 246 3.9E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 SMART SM00490 292 377 2.1E-14 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 Pfam PF08494 DEAD/H associated 630 819 2.9E-47 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 Pfam PF00270 DEAD/DEAH box helicase 30 212 3.6E-21 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 Gene3D G3DSA:3.40.50.300 270 420 3.7E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 16 848 0.0 T 06-07-2017 IPR026362 DEXH box helicase, DNA ligase-associated CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 SUPERFAMILY SSF52540 40 214 1.82E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 SUPERFAMILY SSF52540 245 379 1.82E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05640 14b32c5e71fbcf1568b94b711ef12df2 853 Pfam PF00271 Helicase conserved C-terminal domain 270 372 4.6E-16 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS21165 d1213ecdb5ec8bd4b93fdf6ff42e3537 65 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 7 61 3.1E-19 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAK95_RS21165 d1213ecdb5ec8bd4b93fdf6ff42e3537 65 Gene3D G3DSA:1.20.5.1030 5 61 6.0E-21 T 06-07-2017 CAK95_RS21165 d1213ecdb5ec8bd4b93fdf6ff42e3537 65 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 61 10.646 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21165 d1213ecdb5ec8bd4b93fdf6ff42e3537 65 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 59 2.5E-16 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS27485 d02263007f495ed8eea46a27bd42862a 384 Gene3D G3DSA:3.40.50.2000 1 210 1.0E-83 T 06-07-2017 CAK95_RS27485 d02263007f495ed8eea46a27bd42862a 384 SUPERFAMILY SSF53756 1 376 1.41E-132 T 06-07-2017 CAK95_RS27485 d02263007f495ed8eea46a27bd42862a 384 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 21 368 3.7E-121 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAK95_RS27485 d02263007f495ed8eea46a27bd42862a 384 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 370 6.5E-150 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 CAK95_RS27485 d02263007f495ed8eea46a27bd42862a 384 Gene3D G3DSA:3.40.50.2000 211 369 8.2E-60 T 06-07-2017 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 Pfam PF07702 UTRA domain 122 255 3.9E-29 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 Gene3D G3DSA:3.40.1410.10 95 266 1.5E-37 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 38 99 9.9E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 SUPERFAMILY SSF64288 88 267 3.45E-38 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 Gene3D G3DSA:1.10.10.10 36 94 5.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 SUPERFAMILY SSF46785 35 104 7.87E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 SMART SM00345 41 100 5.9E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 74 90 2.0E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 74 2.0E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS03755 5640da530bd2b67e22d20247ba344d70 269 SMART SM00866 121 261 7.8E-24 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS18560 50aa67ef88aa2c13418a20a953722c01 244 SUPERFAMILY SSF53474 11 241 4.59E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18560 50aa67ef88aa2c13418a20a953722c01 244 Gene3D G3DSA:3.40.50.1820 11 240 1.6E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18560 50aa67ef88aa2c13418a20a953722c01 244 Pfam PF12697 Alpha/beta hydrolase family 12 234 1.1E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20475 c49f4e78ffe73ae5541fedf360607cc4 81 Pfam PF12071 Protein of unknown function (DUF3551) 10 75 4.9E-10 T 06-07-2017 IPR021937 Protein of unknown function DUF3551 CAK95_RS07185 145325d26d11dfa3e706643e4ae8bc67 402 Pfam PF13458 Periplasmic binding protein 28 366 6.8E-80 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS07185 145325d26d11dfa3e706643e4ae8bc67 402 Gene3D G3DSA:3.40.50.2300 25 151 4.6E-22 T 06-07-2017 CAK95_RS07185 145325d26d11dfa3e706643e4ae8bc67 402 Gene3D G3DSA:3.40.50.2300 303 355 4.6E-22 T 06-07-2017 CAK95_RS07185 145325d26d11dfa3e706643e4ae8bc67 402 Gene3D G3DSA:3.40.50.2300 153 302 2.7E-16 T 06-07-2017 CAK95_RS07185 145325d26d11dfa3e706643e4ae8bc67 402 SUPERFAMILY SSF53822 28 399 1.88E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS21470 3a384d7dced32b392484dc2d01d3cd9e 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 138 2.3E-22 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS21470 3a384d7dced32b392484dc2d01d3cd9e 161 SUPERFAMILY SSF55961 2 144 3.18E-31 T 06-07-2017 CAK95_RS21470 3a384d7dced32b392484dc2d01d3cd9e 161 Gene3D G3DSA:3.30.530.20 3 157 2.1E-30 T 06-07-2017 IPR023393 START-like domain CAK95_RS05630 0c35d8e1f53efe8134337a06410aa133 253 Pfam PF09608 Putative transmembrane protein (Alph_Pro_TM) 23 252 7.6E-76 T 06-07-2017 IPR019088 Conserved hypothetical protein CHP02186-related, transmembrane CAK95_RS05630 0c35d8e1f53efe8134337a06410aa133 253 TIGRFAM TIGR02186 alph_Pro_TM: conserved hypothetical protein 16 253 5.5E-85 T 06-07-2017 IPR019088 Conserved hypothetical protein CHP02186-related, transmembrane CAK95_RS12725 650a220420350b735d8186be6711d3c6 293 Gene3D G3DSA:3.10.180.10 5 117 1.5E-10 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS12725 650a220420350b735d8186be6711d3c6 293 SUPERFAMILY SSF54593 5 262 6.8E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS12725 650a220420350b735d8186be6711d3c6 293 Gene3D G3DSA:3.10.180.10 136 281 4.0E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS12725 650a220420350b735d8186be6711d3c6 293 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 137 246 8.5E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS17085 0505d0e5be2e45b5615b34dd546d254e 328 SUPERFAMILY SSF53850 117 288 5.16E-10 T 06-07-2017 CAK95_RS17085 0505d0e5be2e45b5615b34dd546d254e 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 4.2E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17085 0505d0e5be2e45b5615b34dd546d254e 328 PIRSF PIRSF017082 1 327 6.9E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 Gene3D G3DSA:1.10.760.10 38 144 1.3E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 Gene3D G3DSA:1.10.760.10 186 293 1.4E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 SUPERFAMILY SSF46626 179 296 1.17E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 PIRSF PIRSF000018 9 305 6.8E-83 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 SUPERFAMILY SSF46626 28 164 3.63E-22 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 Pfam PF00034 Cytochrome c 42 144 4.1E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17810 74fb846c567ffd5e99806d5e4c94a778 305 Pfam PF00034 Cytochrome c 200 293 2.0E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SMART SM00382 200 345 1.6E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SMART SM00382 599 750 2.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SUPERFAMILY SSF81923 4 158 8.24E-39 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Gene3D G3DSA:1.10.8.60 778 859 7.0E-35 T 06-07-2017 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 1.1E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 1.1E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 1.1E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 1.1E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Gene3D G3DSA:3.40.50.300 555 777 8.4E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 318 2.8E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Gene3D G3DSA:1.10.1780.10 1 149 5.4E-45 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SUPERFAMILY SSF52540 161 547 8.13E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 762 1.3E-56 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.6E-14 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 9.8E-13 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SUPERFAMILY SSF52540 548 850 3.31E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 6.7E-29 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Gene3D G3DSA:3.40.50.300 161 344 1.4E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 SMART SM01086 768 857 4.6E-42 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS02770 b3ed89d061ae3bbaa315ec700557316f 866 Gene3D G3DSA:1.10.8.60 346 430 4.1E-37 T 06-07-2017 CAK95_RS20425 30dc9140b5b7bfa2a6ca9676857501fa 271 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 209 8.3E-31 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS20425 30dc9140b5b7bfa2a6ca9676857501fa 271 SUPERFAMILY SSF111369 38 205 8.76E-22 T 06-07-2017 CAK95_RS20425 30dc9140b5b7bfa2a6ca9676857501fa 271 Gene3D G3DSA:2.40.50.100 38 68 4.2E-12 T 06-07-2017 CAK95_RS20425 30dc9140b5b7bfa2a6ca9676857501fa 271 Gene3D G3DSA:2.40.50.100 129 161 4.2E-12 T 06-07-2017 CAK95_RS20425 30dc9140b5b7bfa2a6ca9676857501fa 271 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 37 207 2.1E-12 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS01105 34e3a0978b10fd59ecf5e8701c540f4e 244 SUPERFAMILY SSF102198 29 241 2.88E-51 T 06-07-2017 CAK95_RS01105 34e3a0978b10fd59ecf5e8701c540f4e 244 Pfam PF04199 Putative cyclase 32 179 1.5E-28 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS01105 34e3a0978b10fd59ecf5e8701c540f4e 244 Gene3D G3DSA:3.50.30.50 29 241 8.4E-58 T 06-07-2017 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 Pfam PF00717 Peptidase S24-like 40 127 2.8E-21 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 ProSitePatterns PS00760 Signal peptidases I lysine active site. 105 117 - T 06-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 Gene3D G3DSA:2.10.109.10 181 232 2.2E-47 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 Gene3D G3DSA:2.10.109.10 29 113 2.2E-47 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 17 224 6.8E-51 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 SUPERFAMILY SSF51306 31 249 4.55E-65 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 103 115 1.7E-23 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 33 49 1.7E-23 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 181 200 1.7E-23 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS22345 14f12006938122e5894aae00962e3f58 250 ProSitePatterns PS00761 Signal peptidases I signature 3. 186 199 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 SUPERFAMILY SSF82607 8 101 4.19E-30 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 21.404 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 3.4E-30 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 4 103 1.9E-24 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 Gene3D G3DSA:3.30.1310.10 1 107 2.3E-39 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS06590 371b3047938e7f92ac44081aab21a3e7 108 PIRSF PIRSF004555 1 107 5.2E-35 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 633 646 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 9.7E-65 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 640 6.9E-117 T 06-07-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 Pfam PF01578 Cytochrome C assembly protein 89 295 8.8E-53 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 1.9E-96 T 06-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS19170 f40afb9e9c6d98edb257df23119cf559 659 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 643 6.9E-186 T 06-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS28700 c5017eb7952f4d32df711352cccdcad0 241 Pfam PF00005 ABC transporter 23 168 3.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28700 c5017eb7952f4d32df711352cccdcad0 241 SUPERFAMILY SSF52540 8 238 8.28E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28700 c5017eb7952f4d32df711352cccdcad0 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28700 c5017eb7952f4d32df711352cccdcad0 241 SMART SM00382 32 224 4.2E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28700 c5017eb7952f4d32df711352cccdcad0 241 Gene3D G3DSA:3.40.50.300 7 234 1.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02425 6122219b87a2c302bc44ad3793a8d773 39 Pfam PF08281 Sigma-70, region 4 1 31 1.2E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02425 6122219b87a2c302bc44ad3793a8d773 39 Gene3D G3DSA:1.10.10.10 1 35 3.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02425 6122219b87a2c302bc44ad3793a8d773 39 SUPERFAMILY SSF88659 2 33 1.46E-7 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS27955 ada953d8c089712ac02c6142e967e340 518 Pfam PF00563 EAL domain 269 501 4.4E-65 T 06-07-2017 IPR001633 EAL domain CAK95_RS27955 ada953d8c089712ac02c6142e967e340 518 SMART SM00052 262 506 6.5E-93 T 06-07-2017 IPR001633 EAL domain CAK95_RS27955 ada953d8c089712ac02c6142e967e340 518 Pfam PF12792 CSS motif domain associated with EAL 37 237 1.8E-33 T 06-07-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain CAK95_RS27955 ada953d8c089712ac02c6142e967e340 518 Gene3D G3DSA:3.20.20.450 269 514 1.7E-81 T 06-07-2017 IPR001633 EAL domain CAK95_RS27955 ada953d8c089712ac02c6142e967e340 518 SUPERFAMILY SSF141868 268 513 1.83E-77 T 06-07-2017 IPR001633 EAL domain CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 SMART SM00986 114 264 2.2E-40 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 Pfam PF03167 Uracil DNA glycosylase superfamily 114 263 2.8E-43 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 Gene3D G3DSA:3.40.470.10 89 271 1.7E-65 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 101 270 1.1E-64 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 SMART SM00987 114 264 2.2E-40 T 06-07-2017 CAK95_RS11165 f9bfa45de5fb0e8e25d26fa003466f14 272 SUPERFAMILY SSF52141 87 270 9.48E-61 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 Pfam PF00202 Aminotransferase class-III 28 414 4.8E-65 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 Gene3D G3DSA:3.40.640.10 65 317 3.4E-58 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 SUPERFAMILY SSF53383 14 414 5.02E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 Gene3D G3DSA:3.90.1150.10 323 415 1.7E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 Gene3D G3DSA:3.90.1150.10 18 64 1.7E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS03670 8e9a23648f2aa7672f0d65840623fe38 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SUPERFAMILY SSF58104 407 673 3.27E-49 T 06-07-2017 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SMART SM00283 434 674 1.4E-30 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 482 673 1.3E-28 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 Gene3D G3DSA:1.10.287.950 436 642 4.5E-40 T 06-07-2017 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 Pfam PF00672 HAMP domain 313 377 8.6E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SUPERFAMILY SSF158472 331 378 7.72E-7 T 06-07-2017 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SMART SM01358 60 302 6.5E-6 T 06-07-2017 IPR032255 Helical bimodular sensor domain CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SMART SM00304 433 486 54.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS11915 6452152cf5c92ab291291bed6b209864 680 SMART SM00304 331 384 1.0E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 SMART SM01130 19 307 3.7E-55 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 PIRSF PIRSF001365 16 312 2.1E-45 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 Pfam PF00701 Dihydrodipicolinate synthetase family 20 298 2.6E-40 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 Gene3D G3DSA:3.20.20.70 20 305 3.9E-62 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 150 167 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 53 74 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 89 107 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS09470 8720f25823324c0d3ade75775e196b1d 312 SUPERFAMILY SSF51569 20 301 2.83E-58 T 06-07-2017 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 SUPERFAMILY SSF46689 227 276 1.34E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 Gene3D G3DSA:1.10.10.60 229 275 4.3E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 Gene3D G3DSA:1.10.10.60 174 228 1.0E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 Pfam PF02311 AraC-like ligand binding domain 22 147 3.1E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 SUPERFAMILY SSF51215 24 149 5.62E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 Pfam PF12833 Helix-turn-helix domain 197 275 6.9E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 SMART SM00342 191 274 1.6E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 Gene3D G3DSA:2.60.120.280 25 123 3.8E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS25405 ae85a9a6cedfc502c9abb1aa2867308d 285 SUPERFAMILY SSF46689 174 224 3.59E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06865 106a94ab5c026e76a593548a4fd23c38 252 Gene3D G3DSA:3.40.50.1820 29 248 1.1E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06865 106a94ab5c026e76a593548a4fd23c38 252 Pfam PF12697 Alpha/beta hydrolase family 31 241 1.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS06865 106a94ab5c026e76a593548a4fd23c38 252 SUPERFAMILY SSF53474 148 245 5.6E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06865 106a94ab5c026e76a593548a4fd23c38 252 SUPERFAMILY SSF53474 21 120 5.6E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 37 313 9.0E-13 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 287 1.2E-53 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 Gene3D G3DSA:3.40.50.720 15 114 1.2E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 SUPERFAMILY SSF51735 106 287 6.59E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 Gene3D G3DSA:3.40.50.720 115 288 6.3E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 SUPERFAMILY SSF52283 1 124 1.96E-23 T 06-07-2017 CAK95_RS12215 a476b62bb2c30c196ff80aaf1cb717d2 318 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 PIRSF PIRSF002811 1 621 4.3E-128 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 TIGRFAM TIGR01391 dnaG: DNA primase 3 414 4.3E-122 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Pfam PF01807 CHC2 zinc finger 5 97 2.4E-24 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Hamap MF_00974 DNA primase [dnaG]. 2 544 23.674 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Gene3D G3DSA:3.90.580.10 1 97 3.6E-31 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Gene3D G3DSA:3.40.1360.10 239 365 8.7E-44 T 06-07-2017 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 SUPERFAMILY SSF56731 112 416 2.22E-97 T 06-07-2017 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 SUPERFAMILY SSF57783 1 98 1.26E-30 T 06-07-2017 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Gene3D G3DSA:3.90.980.10 112 238 3.8E-38 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 SMART SM00400 34 88 3.6E-10 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Pfam PF13662 Toprim domain 258 323 1.5E-15 T 06-07-2017 IPR006171 Toprim domain CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 SMART SM00493 257 328 7.0E-13 T 06-07-2017 IPR006171 Toprim domain CAK95_RS13955 e5b0ac2bd7fea1d6a2543cdf08b915b7 647 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 249 1.6E-37 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 SUPERFAMILY SSF118116 423 612 7.85E-58 T 06-07-2017 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Gene3D G3DSA:3.30.230.10 217 329 8.7E-33 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 SUPERFAMILY SSF54211 202 330 2.12E-33 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 SMART SM00853 427 570 5.1E-55 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 SUPERFAMILY SSF55874 2 199 1.96E-50 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 127 6.3E-11 T 06-07-2017 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 2 310 2.5E-88 T 06-07-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 SMART SM01340 212 330 3.6E-53 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 06-07-2017 IPR014762 DNA mismatch repair, conserved site CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Pfam PF08676 MutL C terminal dimerisation domain 423 570 1.7E-47 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 610 27.312 T 06-07-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Gene3D G3DSA:3.30.565.10 2 200 1.3E-68 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS13345 a6c7b65704bca96896c942f32e5a98a5 613 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 329 1.1E-33 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 139 155 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 8.1E-38 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 SMART SM00138 3 267 2.7E-96 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 SUPERFAMILY SSF53335 71 263 2.41E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 Gene3D G3DSA:1.10.155.10 2 69 1.7E-10 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 260 2.0E-58 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 SUPERFAMILY SSF47757 2 70 2.22E-13 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 54 5.7E-11 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS15160 30628c61ebebdd9c1599de4c8057ebe5 291 Gene3D G3DSA:3.40.50.150 70 264 1.8E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 SMART SM00093 58 424 1.8E-77 T 06-07-2017 IPR023796 Serpin domain CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 Gene3D G3DSA:2.30.39.10 377 424 5.4E-42 T 06-07-2017 CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 Gene3D G3DSA:2.30.39.10 214 315 5.4E-42 T 06-07-2017 CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 Pfam PF00079 Serpin (serine protease inhibitor) 57 424 3.8E-87 T 06-07-2017 IPR023796 Serpin domain CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 ProSitePatterns PS00284 Serpins signature. 397 407 - T 06-07-2017 IPR023795 Serpin, conserved site CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 Gene3D G3DSA:3.30.497.10 316 376 3.9E-53 T 06-07-2017 CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 Gene3D G3DSA:3.30.497.10 59 213 3.9E-53 T 06-07-2017 CAK95_RS25955 68b478f738e5a0182b30b842f3d06266 426 SUPERFAMILY SSF56574 35 424 6.15E-91 T 06-07-2017 IPR023796 Serpin domain CAK95_RS15215 a0d243c35659011b3f51c066ab94c5af 811 Gene3D G3DSA:3.30.1120.10 526 617 2.9E-15 T 06-07-2017 CAK95_RS15215 a0d243c35659011b3f51c066ab94c5af 811 ProSitePatterns PS00523 Sulfatases signature 1. 121 133 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK95_RS15215 a0d243c35659011b3f51c066ab94c5af 811 Pfam PF00884 Sulfatase 77 494 1.3E-72 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS15215 a0d243c35659011b3f51c066ab94c5af 811 SUPERFAMILY SSF53649 77 610 9.42E-112 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS15215 a0d243c35659011b3f51c066ab94c5af 811 Gene3D G3DSA:3.40.720.10 76 522 1.2E-92 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS03795 4e7645abfc3a1ea80c86168badc2b544 78 Gene3D G3DSA:3.40.50.720 38 75 5.8E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 285 362 3.8E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 123 177 3.8E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 627 776 4.6E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 367 455 4.6E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 456 622 1.3E-40 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.90.1170.50 4 122 2.5E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Gene3D G3DSA:3.30.365.10 178 283 1.9E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 SMART SM01008 24 133 2.3E-29 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 SUPERFAMILY SSF56003 125 775 3.14E-170 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 712 6.7E-149 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 25 133 1.4E-11 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25525 add4bb49bea925efc7f896c6b81adbae 787 SUPERFAMILY SSF54665 5 136 6.67E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 211 334 1.7E-22 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 36 165 1.4E-20 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 SUPERFAMILY SSF56601 36 382 1.47E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 Gene3D G3DSA:3.40.710.10 24 89 1.2E-8 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 301 315 1.6E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 244 266 1.6E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 316 330 1.6E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 56 75 1.6E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 Gene3D G3DSA:3.40.710.10 212 333 6.8E-23 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS28225 4a0b7acbfe65550ba25564f656ff8f7e 396 Gene3D G3DSA:3.40.710.10 349 380 2.2E-5 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 263 4.6E-12 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 187 7.4E-45 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 Gene3D G3DSA:1.10.1040.10 192 244 1.2E-9 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 Gene3D G3DSA:3.40.50.720 5 191 1.8E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 211 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 SUPERFAMILY SSF48179 191 259 3.23E-11 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS14940 0c2d40f9b09676535526e7de9215ce19 320 SUPERFAMILY SSF51735 8 187 2.21E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 SUPERFAMILY SSF55124 526 647 6.38E-26 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 639 773 8.1E-23 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 685 701 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 565 629 8.9E-13 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 1.2E-19 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 1.2E-19 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.2E-19 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.2E-19 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 SUPERFAMILY SSF51905 154 311 1.45E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 9.4E-13 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 111 120 9.4E-13 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 9.4E-13 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 9.4E-13 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 SUPERFAMILY SSF56014 640 802 9.95E-46 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Gene3D G3DSA:3.50.50.60 118 311 6.4E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PIRSF PIRSF037149 3 821 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Gene3D G3DSA:3.50.50.60 7 117 5.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Gene3D G3DSA:3.90.480.10 566 635 1.3E-11 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 286 1.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 SUPERFAMILY SSF51905 7 197 2.35E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 12 801 2.9E-276 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 475 2.4E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Pfam PF04324 BFD-like [2Fe-2S] binding domain 490 539 3.0E-10 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 Gene3D G3DSA:3.30.413.10 641 773 3.9E-32 T 06-07-2017 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00397 Sirohaem Fe-binding site signature 642 660 7.3E-7 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS12515 8a15e086a85c0a2cb3dca0466c0a850c 825 PRINTS PR00397 Sirohaem Fe-binding site signature 685 703 7.3E-7 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 Gene3D G3DSA:2.30.130.10 282 372 1.1E-24 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 Gene3D G3DSA:3.40.1160.10 12 262 4.8E-52 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PIRSF PIRSF000729 7 374 5.3E-118 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 SUPERFAMILY SSF53633 12 262 6.28E-64 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PRINTS PR00474 Glutamate 5-kinase family signature 84 112 1.1E-46 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 1.1E-46 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 1.1E-46 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PRINTS PR00474 Glutamate 5-kinase family signature 50 64 1.1E-46 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 PRINTS PR00474 Glutamate 5-kinase family signature 124 145 1.1E-46 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 Pfam PF00696 Amino acid kinase family 13 243 1.1E-42 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 372 6.8E-116 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 SMART SM00359 284 366 1.3E-15 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 Pfam PF01472 PUA domain 286 357 5.1E-20 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 SUPERFAMILY SSF88697 283 373 3.26E-23 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS07310 1bafa8617281b8a8449d48a3b0bdfbdd 376 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 265 34.494 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Gene3D G3DSA:2.40.30.10 198 294 1.9E-27 T 06-07-2017 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Gene3D G3DSA:3.40.50.300 7 197 4.0E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Pfam PF00679 Elongation factor G C-terminus 404 490 9.1E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 8.0E-50 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Gene3D G3DSA:3.30.70.870 298 374 2.9E-26 T 06-07-2017 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 4.7E-10 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 308.747 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 179 1.9E-19 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 SUPERFAMILY SSF54980 404 498 1.34E-24 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 TIGRFAM TIGR01393 lepA: elongation factor 4 8 600 3.6E-297 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Gene3D G3DSA:3.30.70.240 406 494 1.8E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 Pfam PF00009 Elongation factor Tu GTP binding domain 8 186 7.4E-52 T 06-07-2017 CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 SUPERFAMILY SSF54980 298 375 2.12E-18 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS06920 7565a6dbd8b37afa8c24e26f3cd73e77 601 SUPERFAMILY SSF52540 5 240 1.88E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 SUPERFAMILY SSF54637 6 113 8.63E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 Gene3D G3DSA:3.10.129.10 5 114 3.9E-48 T 06-07-2017 IPR029069 HotDog domain CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 Pfam PF13622 Thioesterase-like superfamily 31 281 3.3E-62 T 06-07-2017 CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 Gene3D G3DSA:3.10.129.10 123 284 9.3E-57 T 06-07-2017 IPR029069 HotDog domain CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 SUPERFAMILY SSF54637 115 284 4.97E-57 T 06-07-2017 IPR029069 HotDog domain CAK95_RS08560 aef236ebec6703df4e82cc5e9dc67625 287 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 282 3.1E-91 T 06-07-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 Hamap MF_00109 Shikimate kinase [aroK]. 25 190 28.269 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 Gene3D G3DSA:3.40.50.300 25 189 6.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 SUPERFAMILY SSF52540 25 190 3.45E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 PRINTS PR01100 Shikimate kinase family signature 119 136 1.7E-22 T 06-07-2017 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 PRINTS PR01100 Shikimate kinase family signature 98 107 1.7E-22 T 06-07-2017 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 PRINTS PR01100 Shikimate kinase family signature 28 43 1.7E-22 T 06-07-2017 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 PRINTS PR01100 Shikimate kinase family signature 80 88 1.7E-22 T 06-07-2017 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 PRINTS PR01100 Shikimate kinase family signature 52 65 1.7E-22 T 06-07-2017 CAK95_RS10500 95e27cbfa0d906a31ecdb445c8764bc2 204 Pfam PF01202 Shikimate kinase 34 188 2.1E-48 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK95_RS22455 0b4dca1aaa8a0d890c70d6590b6ab2c0 174 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 23 165 20.462 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAK95_RS22455 0b4dca1aaa8a0d890c70d6590b6ab2c0 174 SUPERFAMILY SSF48013 24 166 9.42E-35 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK95_RS22455 0b4dca1aaa8a0d890c70d6590b6ab2c0 174 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 26 163 1.1E-37 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAK95_RS22455 0b4dca1aaa8a0d890c70d6590b6ab2c0 174 Gene3D G3DSA:1.10.940.10 26 167 3.2E-37 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK95_RS22455 0b4dca1aaa8a0d890c70d6590b6ab2c0 174 Pfam PF01029 NusB family 29 162 5.0E-31 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK95_RS17105 35dd60b46fea21a48e2dfa4d66e01da5 312 SUPERFAMILY SSF51569 5 297 1.83E-67 T 06-07-2017 CAK95_RS17105 35dd60b46fea21a48e2dfa4d66e01da5 312 Pfam PF00682 HMGL-like 7 279 6.2E-44 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK95_RS17105 35dd60b46fea21a48e2dfa4d66e01da5 312 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS17105 35dd60b46fea21a48e2dfa4d66e01da5 312 Gene3D G3DSA:3.20.20.70 6 288 1.5E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 Gene3D G3DSA:3.50.50.60 367 419 1.1E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 Gene3D G3DSA:3.50.50.60 195 275 1.1E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 Gene3D G3DSA:3.50.50.60 42 143 1.1E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 Pfam PF01266 FAD dependent oxidoreductase 54 402 1.5E-52 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 SUPERFAMILY SSF51971 50 287 8.24E-40 T 06-07-2017 CAK95_RS18110 da2deca665a9bdcdabb47ca69d1958c7 530 SUPERFAMILY SSF51971 352 411 8.24E-40 T 06-07-2017 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 ProSitePatterns PS00194 Thioredoxin family active site. 40 58 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Gene3D G3DSA:1.25.40.10 139 217 6.5E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Gene3D G3DSA:1.25.40.10 220 306 5.7E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Pfam PF00085 Thioredoxin 20 124 1.9E-23 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Gene3D G3DSA:3.40.30.10 11 128 4.4E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Pfam PF14561 Tetratricopeptide repeat 218 306 1.6E-33 T 06-07-2017 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 PRINTS PR00421 Thioredoxin family signature 47 56 4.7E-6 T 06-07-2017 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 PRINTS PR00421 Thioredoxin family signature 39 47 4.7E-6 T 06-07-2017 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 PRINTS PR00421 Thioredoxin family signature 91 102 4.7E-6 T 06-07-2017 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 SUPERFAMILY SSF52833 17 128 7.43E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 SUPERFAMILY SSF48452 140 270 1.84E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS08535 5da7860ce470acdf4976f498591c62f5 307 Pfam PF14559 Tetratricopeptide repeat 145 212 6.6E-14 T 06-07-2017 CAK95_RS17740 022705f97bd2c03278e1bc328f465165 288 Gene3D G3DSA:2.60.120.620 70 264 2.6E-6 T 06-07-2017 CAK95_RS17740 022705f97bd2c03278e1bc328f465165 288 SUPERFAMILY SSF51197 70 265 2.75E-13 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:1.20.1580.10 436 508 4.0E-52 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:1.20.1580.10 280 313 4.0E-52 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:1.20.1580.10 109 147 4.0E-52 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 ProSitePatterns PS00211 ABC transporters family signature. 859 873 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 SUPERFAMILY SSF52540 21 222 3.58E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 SUPERFAMILY SSF52540 462 600 3.58E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 22 953 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:1.20.1580.10 723 849 7.3E-53 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.40.50.300 509 625 7.2E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.40.50.300 635 698 5.7E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.40.50.300 850 967 5.7E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.40.50.300 20 69 7.2E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:1.10.8.280 316 435 2.1E-43 T 06-07-2017 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Pfam PF00005 ABC transporter 825 889 4.5E-6 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Hamap MF_00205 UvrABC system protein A [uvrA]. 19 969 22.601 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 SUPERFAMILY SSF52540 651 940 1.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.30.1490.20 218 258 8.1E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS22210 d26d90b171f7bcbf88e201aac6cdab16 983 Gene3D G3DSA:3.30.1490.20 148 171 8.1E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 SMART SM00943 11 192 2.2E-17 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 SUPERFAMILY SSF52540 385 454 6.2E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 SUPERFAMILY SSF52540 512 542 6.2E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 SUPERFAMILY SSF56747 9 179 5.43E-9 T 06-07-2017 CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 Gene3D G3DSA:3.40.50.300 390 439 2.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11680 b3a0844ed4e9d6a82b33113b0f6b6fac 1055 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 15 189 9.5E-14 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAK95_RS11395 0251b12486823325b728eb587482350e 375 SUPERFAMILY SSF56796 6 374 3.01E-107 T 06-07-2017 CAK95_RS11395 0251b12486823325b728eb587482350e 375 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CAK95_RS11395 0251b12486823325b728eb587482350e 375 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 365 5.6E-100 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAK95_RS11395 0251b12486823325b728eb587482350e 375 Gene3D G3DSA:1.20.1090.10 184 375 4.1E-49 T 06-07-2017 CAK95_RS11395 0251b12486823325b728eb587482350e 375 Gene3D G3DSA:3.40.50.1970 6 183 5.0E-52 T 06-07-2017 CAK95_RS08430 ccd0ff977fce73237defbe42aef1fcef 530 SUPERFAMILY SSF48452 89 293 9.87E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS08430 ccd0ff977fce73237defbe42aef1fcef 530 Pfam PF07219 HemY protein N-terminus 26 132 3.4E-28 T 06-07-2017 IPR010817 HemY, N-terminal CAK95_RS08430 ccd0ff977fce73237defbe42aef1fcef 530 PIRSF PIRSF031802 1 528 7.7E-180 T 06-07-2017 IPR016982 Uncharacterised conserved protein UCP031802 CAK95_RS08430 ccd0ff977fce73237defbe42aef1fcef 530 Gene3D G3DSA:1.25.40.10 89 349 9.0E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 SUPERFAMILY SSF48498 134 263 8.89E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 Pfam PF00440 Bacterial regulatory proteins, tetR family 61 106 1.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 ProSitePatterns PS01081 TetR-type HTH domain signature. 73 104 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 Gene3D G3DSA:1.10.357.10 56 262 1.0E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 74 4.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 82 105 4.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS01130 f268f27a1b53ee7e22f906dab4f095b8 266 SUPERFAMILY SSF46689 56 124 6.67E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 Pfam PF00871 Acetokinase family 5 383 1.2E-90 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 SUPERFAMILY SSF53067 159 391 2.89E-71 T 06-07-2017 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 5 16 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 371 383 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 174 187 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 297 310 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 203 224 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PRINTS PR00471 Acetate kinase family signature 319 335 1.3E-32 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 Gene3D G3DSA:3.30.420.40 206 387 3.9E-63 T 06-07-2017 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 SUPERFAMILY SSF53067 4 194 3.56E-49 T 06-07-2017 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 PIRSF PIRSF000722 1 393 1.9E-127 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 Gene3D G3DSA:3.30.420.40 90 205 5.2E-5 T 06-07-2017 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 TIGRFAM TIGR00016 ackA: acetate kinase 3 387 5.8E-92 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS16765 cddeb65b5232659ca243c5f9a8aa1872 394 Hamap MF_00020 Acetate kinase [ackA]. 1 393 137.023 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 SMART SM00116 10 58 1.6E-11 T 06-07-2017 IPR000644 CBS domain CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 SMART SM00116 97 144 7.0E-11 T 06-07-2017 IPR000644 CBS domain CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 Gene3D G3DSA:3.10.580.10 1 144 2.3E-35 T 06-07-2017 CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 PIRSF PIRSF036990 1 235 4.2E-82 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 Pfam PF04972 BON domain 156 222 7.0E-15 T 06-07-2017 IPR007055 BON domain CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 Pfam PF00571 CBS domain 90 144 2.1E-13 T 06-07-2017 IPR000644 CBS domain CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 Pfam PF00571 CBS domain 3 56 2.7E-13 T 06-07-2017 IPR000644 CBS domain CAK95_RS18475 1522fa21c75d25e48661fba130ae5381 245 SUPERFAMILY SSF54631 1 143 1.11E-35 T 06-07-2017 CAK95_RS15175 ae3609fd846b6e2f44fb8c6106338f64 410 SUPERFAMILY SSF111369 180 251 1.05E-5 T 06-07-2017 CAK95_RS15175 ae3609fd846b6e2f44fb8c6106338f64 410 SUPERFAMILY SSF111369 70 146 7.98E-6 T 06-07-2017 CAK95_RS15175 ae3609fd846b6e2f44fb8c6106338f64 410 Gene3D G3DSA:2.40.50.100 227 251 2.7E-11 T 06-07-2017 CAK95_RS15175 ae3609fd846b6e2f44fb8c6106338f64 410 Gene3D G3DSA:2.40.50.100 75 107 2.7E-11 T 06-07-2017 CAK95_RS15175 ae3609fd846b6e2f44fb8c6106338f64 410 Pfam PF13533 Biotin-lipoyl like 75 121 1.4E-8 T 06-07-2017 CAK95_RS19600 76ae3c9b7724a3429af500e507d9761f 811 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 182 388 7.4E-11 T 06-07-2017 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 CAK95_RS19600 76ae3c9b7724a3429af500e507d9761f 811 Gene3D G3DSA:3.40.50.300 420 581 2.4E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19600 76ae3c9b7724a3429af500e507d9761f 811 Gene3D G3DSA:3.40.50.300 629 704 2.4E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19600 76ae3c9b7724a3429af500e507d9761f 811 SMART SM00382 440 707 1.7E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS19600 76ae3c9b7724a3429af500e507d9761f 811 SUPERFAMILY SSF52540 398 747 6.09E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19400 e0332c72833c654e40d834e03cee7dae 430 Pfam PF13657 HipA N-terminal domain 30 122 4.5E-7 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAK95_RS19400 e0332c72833c654e40d834e03cee7dae 430 Pfam PF07805 HipA-like N-terminal domain 175 244 3.9E-12 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAK95_RS19400 e0332c72833c654e40d834e03cee7dae 430 Pfam PF07804 HipA-like C-terminal domain 253 391 1.5E-27 T 06-07-2017 IPR012893 HipA-like, C-terminal CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Pfam PF13328 HD domain 58 207 2.8E-49 T 06-07-2017 IPR003607 HD/PDEase domain CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SUPERFAMILY SSF55021 690 761 5.34E-10 T 06-07-2017 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SMART SM00954 267 377 1.1E-58 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Pfam PF02824 TGS domain 424 482 9.0E-19 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Gene3D G3DSA:3.10.20.30 422 484 3.8E-21 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Gene3D G3DSA:3.30.460.10 210 356 2.9E-44 T 06-07-2017 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SUPERFAMILY SSF81271 410 483 8.72E-20 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 58 758 1.9E-198 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SUPERFAMILY SSF109604 36 222 4.08E-69 T 06-07-2017 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Pfam PF04607 Region found in RelA / SpoT proteins 267 376 2.9E-35 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Gene3D G3DSA:3.30.70.260 687 751 6.3E-11 T 06-07-2017 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SMART SM00471 73 185 1.4E-11 T 06-07-2017 IPR003607 HD/PDEase domain CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 Pfam PF13291 ACT domain 685 761 2.1E-17 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS22330 4638a69956aff33f3ffa362abace06ad 764 SUPERFAMILY SSF81301 213 427 2.78E-59 T 06-07-2017 CAK95_RS11380 b0a751c5c4cc0d99b8d7fcfdec9afc96 482 Gene3D G3DSA:3.40.605.10 8 263 8.6E-84 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS11380 b0a751c5c4cc0d99b8d7fcfdec9afc96 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS11380 b0a751c5c4cc0d99b8d7fcfdec9afc96 482 SUPERFAMILY SSF53720 5 479 4.32E-149 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS11380 b0a751c5c4cc0d99b8d7fcfdec9afc96 482 Pfam PF00171 Aldehyde dehydrogenase family 17 478 4.4E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS11380 b0a751c5c4cc0d99b8d7fcfdec9afc96 482 Gene3D G3DSA:3.40.309.10 264 442 4.3E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS02720 f0b96a0750256fa343b7eb754c61f6bd 348 Pfam PF09084 NMT1/THI5 like 45 261 6.5E-41 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS02720 f0b96a0750256fa343b7eb754c61f6bd 348 Gene3D G3DSA:3.40.190.10 119 246 4.2E-14 T 06-07-2017 CAK95_RS02720 f0b96a0750256fa343b7eb754c61f6bd 348 SUPERFAMILY SSF53850 30 266 8.93E-38 T 06-07-2017 CAK95_RS27605 dd2cda2d2e848a179e114b85436b7b60 39 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 17 39 1.9E-11 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAK95_RS27605 dd2cda2d2e848a179e114b85436b7b60 39 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 17 39 4.2E-9 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAK95_RS11220 59a96aba028c7fcaff7a709a29020a23 161 Gene3D G3DSA:1.10.490.10 31 135 7.1E-23 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK95_RS11220 59a96aba028c7fcaff7a709a29020a23 161 SUPERFAMILY SSF46458 30 137 5.67E-30 T 06-07-2017 IPR009050 Globin-like CAK95_RS11220 59a96aba028c7fcaff7a709a29020a23 161 Pfam PF01152 Bacterial-like globin 31 135 3.4E-7 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 CAK95_RS00540 4338bd02c5937bc8a8f3ed48d096a8b3 182 Gene3D G3DSA:3.40.50.2020 8 180 3.1E-67 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS00540 4338bd02c5937bc8a8f3ed48d096a8b3 182 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 10 179 36.68 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAK95_RS00540 4338bd02c5937bc8a8f3ed48d096a8b3 182 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 178 7.4E-64 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAK95_RS00540 4338bd02c5937bc8a8f3ed48d096a8b3 182 Pfam PF00156 Phosphoribosyl transferase domain 37 159 6.2E-17 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS00540 4338bd02c5937bc8a8f3ed48d096a8b3 182 SUPERFAMILY SSF53271 6 179 1.57E-53 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 286 299 2.4E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 2.4E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 2.4E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 2.4E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 Pfam PF13458 Periplasmic binding protein 27 377 1.2E-62 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 SUPERFAMILY SSF53822 27 382 1.13E-81 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 Gene3D G3DSA:3.40.50.2300 153 310 5.7E-30 T 06-07-2017 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 Gene3D G3DSA:3.40.50.2300 23 150 1.1E-51 T 06-07-2017 CAK95_RS17415 6c21eb3d913630717b983a39d93dfde7 383 Gene3D G3DSA:3.40.50.2300 311 363 1.1E-51 T 06-07-2017 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 SMART SM01008 189 295 1.6E-44 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.90.1170.50 178 292 9.5E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 55 3.6E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 SUPERFAMILY SSF56003 287 594 2.49E-92 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.30.365.10 522 590 2.1E-12 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 SUPERFAMILY SSF54292 5 81 4.98E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.30.365.10 296 339 1.7E-43 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.30.365.10 446 520 1.7E-43 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.10.20.30 5 77 1.1E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 SUPERFAMILY SSF47741 87 187 6.02E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:1.10.150.120 78 177 7.9E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 190 292 2.5E-27 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 SUPERFAMILY SSF54665 167 317 9.68E-44 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Gene3D G3DSA:3.30.365.10 340 444 2.0E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 311 588 9.0E-92 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10075 2e2a4a7d0af427c98e3f62197432ed89 627 Pfam PF01799 [2Fe-2S] binding domain 76 148 1.1E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 Pfam PF00682 HMGL-like 6 255 1.7E-46 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 Pfam PF08502 LeuA allosteric (dimerisation) domain 379 520 5.0E-29 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 SMART SM00917 379 524 2.8E-38 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 SUPERFAMILY SSF110921 421 520 2.48E-21 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 Gene3D G3DSA:3.20.20.70 3 352 4.0E-118 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 SUPERFAMILY SSF51569 4 297 1.01E-80 T 06-07-2017 CAK95_RS20055 fd47a8076d48f97a8d1a9335e358061a 531 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 6 527 4.5E-197 T 06-07-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CAK95_RS02690 aae2eb39949ebffe98ab42344e359d6f 697 SUPERFAMILY SSF55874 42 206 2.36E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS02690 aae2eb39949ebffe98ab42344e359d6f 697 Gene3D G3DSA:3.30.565.10 43 225 2.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 326 1.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 9.7E-9 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 9.7E-9 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.7E-9 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 Gene3D G3DSA:3.50.50.60 105 334 1.4E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.6E-10 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.6E-10 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 2.6E-10 T 06-07-2017 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 Gene3D G3DSA:3.50.50.60 2 104 2.5E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08605 5a800fca85ccbfe4a0ffc50532c2cb7e 439 SUPERFAMILY SSF51905 1 340 8.39E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.6E-162 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 41.89 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 SUPERFAMILY SSF52210 239 385 1.7E-54 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Pfam PF00549 CoA-ligase 262 381 1.8E-28 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 SUPERFAMILY SSF56059 1 238 1.06E-80 T 06-07-2017 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Gene3D G3DSA:3.30.1490.20 22 94 2.8E-33 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Gene3D G3DSA:3.40.50.261 241 383 7.7E-67 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Gene3D G3DSA:3.30.470.20 95 239 1.1E-59 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 Pfam PF08442 ATP-grasp domain 2 203 2.2E-75 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS07490 dfe06f45db94b5d96ca1da5fa4b9573e 387 PIRSF PIRSF001554 1 387 1.5E-155 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS09590 81fe7f7449a4e5ee5f7ab77a1e7a6d5d 127 SMART SM00450 19 122 3.3E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS09590 81fe7f7449a4e5ee5f7ab77a1e7a6d5d 127 SUPERFAMILY SSF52821 7 125 1.09E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS09590 81fe7f7449a4e5ee5f7ab77a1e7a6d5d 127 Gene3D G3DSA:3.40.250.10 6 125 3.1E-27 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS09590 81fe7f7449a4e5ee5f7ab77a1e7a6d5d 127 Pfam PF00581 Rhodanese-like domain 21 117 1.0E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS22450 c9addd1c9b5e3e819fcdde165589d4d8 166 SUPERFAMILY SSF52121 15 162 2.49E-47 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22450 c9addd1c9b5e3e819fcdde165589d4d8 166 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 161 25.007 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22450 c9addd1c9b5e3e819fcdde165589d4d8 166 Gene3D G3DSA:3.40.50.960 11 159 1.4E-48 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22450 c9addd1c9b5e3e819fcdde165589d4d8 166 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 19 158 8.7E-43 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22450 c9addd1c9b5e3e819fcdde165589d4d8 166 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 20 155 5.6E-31 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS04005 17d97e0a23a00086394f36320846edec 150 Pfam PF02472 Biopolymer transport protein ExbD/TolR 22 145 2.7E-30 T 06-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CAK95_RS04005 17d97e0a23a00086394f36320846edec 150 TIGRFAM TIGR02801 tolR: protein TolR 23 145 5.5E-42 T 06-07-2017 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 Gene3D G3DSA:3.30.465.10 59 174 4.0E-31 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 SUPERFAMILY SSF55447 183 282 4.58E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 185 281 4.9E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 1.3E-41 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 SMART SM01092 179 282 6.5E-18 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 SUPERFAMILY SSF56176 3 174 1.53E-46 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 Gene3D G3DSA:3.30.43.10 1 53 4.5E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS14170 eeab0aaed25c152e65171df9aa3c3f4c 291 Gene3D G3DSA:3.30.390.50 184 284 6.8E-18 T 06-07-2017 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Gene3D G3DSA:3.90.760.10 355 423 1.3E-21 T 06-07-2017 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 SUPERFAMILY SSF51905 145 280 1.28E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 32 148 2.1E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Gene3D G3DSA:3.50.50.60 30 146 5.7E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Gene3D G3DSA:3.50.50.60 282 348 5.7E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 SUPERFAMILY SSF55424 355 423 2.55E-18 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 SUPERFAMILY SSF51905 32 138 1.6E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 SUPERFAMILY SSF51905 276 350 1.6E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 357 422 2.9E-20 T 06-07-2017 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 33 52 5.4E-5 T 06-07-2017 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 5.4E-5 T 06-07-2017 CAK95_RS23485 00afcec26bcea75074b6dcb0e7a2cb3c 423 Gene3D G3DSA:3.50.50.60 148 281 3.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 68 83 6.2E-55 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 120 144 6.2E-55 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 169 184 6.2E-55 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 89 109 6.2E-55 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 146 166 6.2E-55 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 Gene3D G3DSA:3.30.930.10 13 221 2.6E-101 T 06-07-2017 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 14 314 58.427 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 15 310 4.0E-138 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 SUPERFAMILY SSF55681 15 311 7.95E-126 T 06-07-2017 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 16 311 1.0E-144 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00525 0e4cfc604f80cbae547eb171eaca74b2 317 Gene3D G3DSA:1.20.58.180 223 313 1.2E-32 T 06-07-2017 CAK95_RS05965 3d38e52fb1f0cb076a06322e436c7b96 254 Gene3D G3DSA:3.40.50.300 2 214 9.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05965 3d38e52fb1f0cb076a06322e436c7b96 254 SMART SM00382 34 215 2.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS05965 3d38e52fb1f0cb076a06322e436c7b96 254 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05965 3d38e52fb1f0cb076a06322e436c7b96 254 Pfam PF00005 ABC transporter 27 165 1.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05965 3d38e52fb1f0cb076a06322e436c7b96 254 SUPERFAMILY SSF52540 6 236 3.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:1.10.287.560 190 250 1.1E-18 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:2.40.50.180 623 681 6.5E-7 T 06-07-2017 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:2.40.50.180 469 527 2.4E-14 T 06-07-2017 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF55874 252 435 9.43E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 436 1.8E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:2.30.30.40 528 571 2.2E-19 T 06-07-2017 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:2.30.30.40 437 458 2.2E-19 T 06-07-2017 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF50341 598 720 1.29E-11 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Pfam PF01627 Hpt domain 3 94 6.8E-16 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SMART SM00073 1 97 4.8E-24 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF52172 744 859 1.99E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:3.40.50.2300 741 859 1.7E-31 T 06-07-2017 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Pfam PF00072 Response regulator receiver domain 747 854 4.9E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF47226 1 121 2.22E-27 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SMART SM01231 189 249 6.0E-17 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SMART SM00448 744 854 7.4E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF47384 190 250 2.04E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 6.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 6.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 6.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SUPERFAMILY SSF50341 436 571 1.7E-27 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 191 249 1.6E-13 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Pfam PF01584 CheW-like domain 442 573 6.6E-22 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SMART SM00260 429 572 2.4E-35 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:3.30.565.10 254 436 7.3E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 Gene3D G3DSA:1.20.120.160 1 132 3.0E-33 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS15140 72aea64e52c0f9d72c6cae2a706e7ea8 866 SMART SM00387 294 437 5.6E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 Gene3D G3DSA:3.40.1010.10 26 133 1.4E-13 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 PIRSF PIRSF005917 15 297 9.2E-99 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 26 222 7.6E-29 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 103 114 - T 06-07-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 SUPERFAMILY SSF53790 25 242 1.31E-76 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 26 292 8.0E-75 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 25 244 36.737 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08855 506824150b2bf78d092a1525554c900f 302 Gene3D G3DSA:3.30.950.10 134 245 3.4E-38 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 SUPERFAMILY SSF53850 32 256 2.04E-47 T 06-07-2017 CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 Gene3D G3DSA:3.40.190.10 39 131 2.2E-17 T 06-07-2017 CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 Gene3D G3DSA:3.40.190.10 231 249 2.2E-17 T 06-07-2017 CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 249 5.1E-28 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 Gene3D G3DSA:3.40.190.10 132 228 2.4E-10 T 06-07-2017 CAK95_RS01225 0704067de2f31d096d75e0d4daf1371f 343 SMART SM00062 41 271 3.8E-42 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 Gene3D G3DSA:1.10.10.10 9 77 1.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 SUPERFAMILY SSF48008 83 228 4.97E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 SMART SM00345 18 76 4.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 6.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 6.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 Pfam PF07729 FCD domain 86 221 1.5E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 SUPERFAMILY SSF46785 18 106 7.18E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 SMART SM00895 86 223 6.2E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 76 2.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS06140 cca16fe78c993cc35d1da782125c4d3d 255 Gene3D G3DSA:1.20.120.530 79 233 4.4E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 SMART SM00100 29 147 9.0E-8 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 SMART SM00419 177 226 2.2E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 SUPERFAMILY SSF51206 43 157 7.99E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 199 3.0E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 199 214 3.0E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 Pfam PF00027 Cyclic nucleotide-binding domain 48 129 2.0E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 Gene3D G3DSA:2.60.120.10 49 152 8.5E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 ProSitePatterns PS00042 Crp-type HTH domain signature. 185 208 - T 06-07-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 SUPERFAMILY SSF46785 160 232 5.98E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 Pfam PF13545 Crp-like helix-turn-helix domain 163 231 8.7E-18 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS16745 a1e664e7d0d8ca2fd6771b87f42f6383 235 Gene3D G3DSA:1.10.10.10 161 224 7.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 Gene3D G3DSA:3.40.50.1580 189 480 1.2E-105 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 23 180 2.5E-54 T 06-07-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 Gene3D G3DSA:3.30.1730.10 15 183 1.3E-58 T 06-07-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 Pfam PF01048 Phosphorylase superfamily 288 448 6.1E-11 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 SUPERFAMILY SSF53167 19 500 1.57E-145 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 22 500 2.2E-195 T 06-07-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAK95_RS20520 cf2f4b3846dfffed999a8433fbfe3a25 500 Hamap MF_01932 AMP nucleosidase [amn]. 14 500 60.989 T 06-07-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAK95_RS07955 1681dd3145050e630c32cf5ba102df37 157 Gene3D G3DSA:2.30.110.10 3 156 6.3E-49 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS07955 1681dd3145050e630c32cf5ba102df37 157 SUPERFAMILY SSF50475 2 130 4.3E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS07955 1681dd3145050e630c32cf5ba102df37 157 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 4 148 8.0E-45 T 06-07-2017 CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 SUPERFAMILY SSF53850 35 317 1.63E-43 T 06-07-2017 CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 Gene3D G3DSA:3.40.190.10 121 239 1.3E-12 T 06-07-2017 CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 Pfam PF16868 NMT1-like family 52 316 2.5E-31 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 Gene3D G3DSA:3.40.190.10 35 114 8.4E-25 T 06-07-2017 CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 Gene3D G3DSA:3.40.190.10 247 317 8.4E-25 T 06-07-2017 CAK95_RS24175 85af233287c3366bbf3a4ff6927e94d8 325 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 21 317 4.1E-40 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 SUPERFAMILY SSF55979 243 364 6.91E-14 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 SMART SM00480 14 361 8.0E-49 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Gene3D G3DSA:3.10.150.10 1 117 4.5E-22 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 243 364 9.2E-10 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Gene3D G3DSA:3.10.150.10 124 243 5.6E-24 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 PIRSF PIRSF000804 1 365 3.4E-67 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 SUPERFAMILY SSF55979 1 117 4.13E-18 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 116 2.0E-19 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Gene3D G3DSA:3.10.150.10 244 364 9.7E-15 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 SUPERFAMILY SSF55979 126 240 1.18E-16 T 06-07-2017 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 364 4.8E-54 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS24525 9c9e9c4102f937ab1013d852a86a4b3f 365 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 239 3.4E-13 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 414 1.6E-141 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 1.9E-36 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Gene3D G3DSA:1.20.5.100 205 231 4.3E-19 T 06-07-2017 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 SMART SM00984 317 418 3.3E-49 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 6.0E-32 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 PIRSF PIRSF000124 1 433 7.8E-147 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 SUPERFAMILY SSF51735 1 205 2.3E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Gene3D G3DSA:3.40.50.720 232 434 2.7E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 SUPERFAMILY SSF48179 201 298 2.89E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 183 1.0E-69 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 SUPERFAMILY SSF52413 302 428 9.16E-40 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 PIRSF PIRSF500134 1 434 4.8E-182 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 CAK95_RS06775 8cc321d38e9fdc0834ce5c8f9756590a 434 Gene3D G3DSA:3.40.50.720 1 204 1.5E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 7.0E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 Gene3D G3DSA:3.90.180.10 3 146 1.2E-46 T 06-07-2017 IPR011032 GroES-like CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 Pfam PF00107 Zinc-binding dehydrogenase 152 254 9.8E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 SUPERFAMILY SSF50129 4 145 7.01E-41 T 06-07-2017 IPR011032 GroES-like CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 SMART SM00829 11 323 5.1E-33 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 SUPERFAMILY SSF51735 112 273 5.64E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23540 f9920595355ff075be3dd2a5d59562d5 325 Gene3D G3DSA:3.40.50.720 147 256 1.2E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 12 174 23.296 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 Gene3D G3DSA:2.30.30.240 103 173 6.7E-12 T 06-07-2017 CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 Pfam PF01782 RimM N-terminal domain 15 93 4.4E-23 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 Pfam PF05239 PRC-barrel domain 100 173 1.9E-7 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 13 173 1.4E-39 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 Gene3D G3DSA:2.40.30.60 10 97 1.7E-26 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 SUPERFAMILY SSF50346 103 173 2.28E-12 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS07655 34f144a0e58ff84f1edc153c7473c2b2 185 SUPERFAMILY SSF50447 13 96 2.08E-20 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 Pfam PF13406 Transglycosylase SLT domain 31 332 1.9E-92 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 30 336 4.7E-105 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 Pfam PF01471 Putative peptidoglycan binding domain 355 407 1.5E-8 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 Gene3D G3DSA:1.10.530.10 221 338 7.1E-48 T 06-07-2017 CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 Gene3D G3DSA:1.10.530.10 83 140 7.1E-48 T 06-07-2017 CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 Gene3D G3DSA:1.10.101.10 350 407 1.9E-7 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 SUPERFAMILY SSF47090 350 407 1.05E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS02000 cf548384b38c6df8027f8ab4634a2a54 411 SUPERFAMILY SSF53955 18 337 2.06E-83 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS22565 3a9ac2d35b4f3834abcbf94fbb045b10 359 Gene3D G3DSA:3.40.50.150 129 331 5.0E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS22565 3a9ac2d35b4f3834abcbf94fbb045b10 359 Pfam PF13489 Methyltransferase domain 139 247 9.0E-10 T 06-07-2017 CAK95_RS22565 3a9ac2d35b4f3834abcbf94fbb045b10 359 SUPERFAMILY SSF53335 132 359 7.92E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 360 495 6.6E-19 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 SMART SM00382 356 500 4.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 710 729 1.6E-56 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 733 751 1.6E-56 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 602 618 1.6E-56 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 680 699 1.6E-56 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 364 383 1.6E-56 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 SUPERFAMILY SSF88697 21 210 8.95E-47 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 PIRSF PIRSF001174 6 782 0.0 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 20 210 2.0E-38 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Hamap MF_01973 Lon protease [lon]. 20 779 72.154 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 SUPERFAMILY SSF52540 321 593 1.44E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Gene3D G3DSA:1.10.8.60 508 591 5.8E-31 T 06-07-2017 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 SMART SM00464 19 211 7.0E-75 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 TIGRFAM TIGR00763 lon: endopeptidase La 21 778 9.8E-303 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Gene3D G3DSA:3.40.50.300 318 507 4.5E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 SUPERFAMILY SSF54211 602 777 9.48E-57 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Gene3D G3DSA:3.30.230.10 597 777 8.5E-73 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 683 691 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CAK95_RS22715 9df34c74647d59ab76586626e0895cea 809 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 577 779 5.6E-97 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAK95_RS07035 57c07039433d1ca59a594502c1b284ae 384 Gene3D G3DSA:3.40.640.10 56 269 1.1E-20 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS07035 57c07039433d1ca59a594502c1b284ae 384 Pfam PF00266 Aminotransferase class-V 95 355 1.2E-8 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS07035 57c07039433d1ca59a594502c1b284ae 384 SUPERFAMILY SSF53383 13 384 1.07E-38 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS07035 57c07039433d1ca59a594502c1b284ae 384 Gene3D G3DSA:3.90.1150.10 270 384 4.3E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 Gene3D G3DSA:3.40.190.10 150 317 9.0E-71 T 06-07-2017 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PIRSF PIRSF019574 1 369 1.3E-145 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 313 339 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 36 52 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 79 93 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 268 287 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 158 172 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 181 200 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 218 237 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 95 108 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 52 73 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 128 144 4.2E-65 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 Gene3D G3DSA:3.40.190.10 40 149 2.1E-10 T 06-07-2017 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 Pfam PF13416 Bacterial extracellular solute-binding protein 46 325 6.7E-32 T 06-07-2017 CAK95_RS20140 2547b257402a16b3b6a15e253981290b 369 SUPERFAMILY SSF53850 33 368 9.0E-99 T 06-07-2017 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 112 122 - T 06-07-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Gene3D G3DSA:3.40.50.300 257 450 1.8E-153 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Gene3D G3DSA:3.40.50.300 23 137 1.8E-153 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Gene3D G3DSA:3.30.1510.10 138 256 2.4E-56 T 06-07-2017 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 9 565 49.241 T 06-07-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 SUPERFAMILY SSF52540 12 563 1.43E-249 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Gene3D G3DSA:3.10.410.10 453 541 1.5E-37 T 06-07-2017 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 Pfam PF01268 Formate--tetrahydrofolate ligase 10 565 5.3E-273 T 06-07-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS12765 daf3cfe736335275bbb3404e00443e96 565 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 337 348 - T 06-07-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 Gene3D G3DSA:1.10.150.120 79 158 1.3E-35 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 57 2.5E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 SUPERFAMILY SSF54292 4 92 8.26E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 Pfam PF01799 [2Fe-2S] binding domain 77 149 3.0E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 SUPERFAMILY SSF47741 88 157 1.96E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27780 bcd7599cb826cef0867c1d8ce66ae2de 159 Gene3D G3DSA:3.10.20.30 4 78 2.5E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 152 6.2E-44 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 33 152 1.9E-43 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 113 134 - T 06-07-2017 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 84 139 2.0E-20 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 SUPERFAMILY SSF143243 8 185 2.35E-58 T 06-07-2017 CAK95_RS22835 27286523ccfe0040246d96f2fa0ad5f2 200 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 160 30.462 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS26535 d88c912cbabc0db04d2855c9a7b403e6 105 Pfam PF07345 Domain of unknown function (DUF1476) 1 100 4.4E-42 T 06-07-2017 IPR009945 Protein of unknown function DUF1476 CAK95_RS26535 d88c912cbabc0db04d2855c9a7b403e6 105 PIRSF PIRSF031780 1 105 1.8E-47 T 06-07-2017 IPR009945 Protein of unknown function DUF1476 CAK95_RS26590 83295d7c35b4c5033ea98ff31f83ccd1 584 SUPERFAMILY SSF51735 415 551 9.45E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26590 83295d7c35b4c5033ea98ff31f83ccd1 584 Pfam PF00999 Sodium/hydrogen exchanger family 11 388 5.2E-58 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK95_RS26590 83295d7c35b4c5033ea98ff31f83ccd1 584 Gene3D G3DSA:3.40.50.720 414 549 3.0E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26590 83295d7c35b4c5033ea98ff31f83ccd1 584 Pfam PF02254 TrkA-N domain 420 533 2.1E-20 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK95_RS09490 758432dc75374345a87a0bf633cdea5d 218 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 46 201 1.3E-66 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS09490 758432dc75374345a87a0bf633cdea5d 218 Pfam PF01625 Peptide methionine sulfoxide reductase 48 201 1.1E-65 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS09490 758432dc75374345a87a0bf633cdea5d 218 Gene3D G3DSA:3.30.1060.10 10 201 4.5E-80 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS09490 758432dc75374345a87a0bf633cdea5d 218 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 207 36.761 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS09490 758432dc75374345a87a0bf633cdea5d 218 SUPERFAMILY SSF55068 8 211 1.96E-80 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 Pfam PF00072 Response regulator receiver domain 8 116 2.4E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 Gene3D G3DSA:3.40.50.2300 8 122 5.9E-26 T 06-07-2017 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 SUPERFAMILY SSF46689 124 174 1.51E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 Pfam PF02954 Bacterial regulatory protein, Fis family 135 173 3.0E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 SUPERFAMILY SSF52172 6 125 1.08E-27 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 SMART SM00448 5 116 7.1E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 157 177 3.9E-7 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 140 157 3.9E-7 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS09350 a0df05c681f357955fd7b13c1538431b 177 Gene3D G3DSA:1.10.10.60 123 176 5.2E-25 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00412 Epoxide hydrolase signature 80 93 6.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00412 Epoxide hydrolase signature 37 52 6.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00412 Epoxide hydrolase signature 17 35 6.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00412 Epoxide hydrolase signature 228 250 6.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 Pfam PF12697 Alpha/beta hydrolase family 13 246 4.3E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 9.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 9.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 197 211 9.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 9.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 Gene3D G3DSA:3.40.50.1820 3 253 7.8E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27060 4d3b1c6a36df9a494982a9cfc3f072b4 271 SUPERFAMILY SSF53474 11 253 2.18E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 Gene3D G3DSA:1.10.10.60 27 83 3.5E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 Gene3D G3DSA:3.30.160.70 121 207 2.6E-23 T 06-07-2017 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 SUPERFAMILY SSF53155 133 206 1.96E-15 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 SMART SM00342 45 127 7.0E-12 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 SUPERFAMILY SSF46689 28 79 2.24E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 Gene3D G3DSA:1.10.10.10 215 296 1.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 216 294 9.5E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 218 295 7.4E-30 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 266 272 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 SUPERFAMILY SSF46767 215 295 7.72E-30 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS08960 d223d958012764ac9613a3bb30c707d7 300 Pfam PF12833 Helix-turn-helix domain 51 127 6.6E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Gene3D G3DSA:3.40.47.10 152 199 1.5E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Gene3D G3DSA:3.40.47.10 284 401 1.5E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 400 5.5E-137 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 PIRSF PIRSF000429 1 402 3.3E-135 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 SUPERFAMILY SSF53901 3 277 4.01E-81 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Gene3D G3DSA:3.40.47.10 3 125 2.4E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Gene3D G3DSA:3.40.47.10 200 283 2.4E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Pfam PF02803 Thiolase, C-terminal domain 278 400 4.2E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 2 402 4.5E-213 T 06-07-2017 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 SUPERFAMILY SSF53901 278 401 3.46E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 Pfam PF00108 Thiolase, N-terminal domain 4 269 8.3E-78 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS06165 fe9f9455a03982cccd3d569af200fb67 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 SUPERFAMILY SSF47384 165 241 1.86E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 403 5.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 5.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 5.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 384 5.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 SMART SM00388 176 243 1.5E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 SMART SM00387 289 406 6.2E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 177 241 5.6E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 SUPERFAMILY SSF55874 232 404 5.11E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 404 1.3E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 SUPERFAMILY SSF55785 60 152 2.66E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 Gene3D G3DSA:1.10.287.130 170 228 3.9E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 Gene3D G3DSA:3.30.565.10 229 404 3.5E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05895 366b801ad72e217b5f9c2aff01ac9b4e 416 Gene3D G3DSA:3.30.450.20 60 167 1.8E-7 T 06-07-2017 CAK95_RS05930 22a13e406fc9e188e951b5da1f558659 338 SUPERFAMILY SSF51679 4 323 2.71E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS05930 22a13e406fc9e188e951b5da1f558659 338 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 324 7.6E-131 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAK95_RS05930 22a13e406fc9e188e951b5da1f558659 338 Gene3D G3DSA:3.20.20.30 3 323 9.6E-87 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS05930 22a13e406fc9e188e951b5da1f558659 338 Pfam PF00296 Luciferase-like monooxygenase 20 300 2.4E-36 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 3 414 6.0E-194 T 06-07-2017 IPR030835 Sulfite dehydrogenase SoxC CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 Gene3D G3DSA:2.60.40.650 291 406 4.3E-25 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 Gene3D G3DSA:3.90.420.10 68 290 5.4E-69 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 231 244 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 214 230 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 247 260 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 91 107 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 370 382 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 313 327 8.8E-18 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 Pfam PF00174 Oxidoreductase molybdopterin binding domain 103 263 2.0E-50 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 284 401 6.8E-20 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 SUPERFAMILY SSF56524 53 293 1.28E-75 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 SUPERFAMILY SSF81296 289 406 8.4E-30 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK95_RS23470 56607e15b5ad45ec26188ec581a77253 417 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 28 3.9E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS12585 5754bd032d07d18b640490c3447d4b47 321 Gene3D G3DSA:3.40.50.720 2 239 1.3E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12585 5754bd032d07d18b640490c3447d4b47 321 SUPERFAMILY SSF51735 2 301 7.11E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12585 5754bd032d07d18b640490c3447d4b47 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 214 2.0E-23 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS02880 33948d27801c5ad3e0630aee9477a779 358 Gene3D G3DSA:3.40.50.150 174 346 8.6E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02880 33948d27801c5ad3e0630aee9477a779 358 SUPERFAMILY SSF53335 153 346 3.38E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02880 33948d27801c5ad3e0630aee9477a779 358 Pfam PF08241 Methyltransferase domain 197 294 2.8E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 Gene3D G3DSA:3.40.50.300 379 595 4.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 Pfam PF00664 ABC transporter transmembrane region 47 328 9.6E-9 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 SMART SM00382 404 592 3.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 SUPERFAMILY SSF90123 31 359 3.79E-22 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 Gene3D G3DSA:1.20.1560.10 31 359 5.6E-20 T 06-07-2017 CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 SUPERFAMILY SSF52540 370 593 2.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17715 ddd13a16a88a230cc4b4e77b7a1fb224 606 Pfam PF00005 ABC transporter 396 544 7.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 Gene3D G3DSA:1.20.140.10 208 391 2.0E-29 T 06-07-2017 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 PIRSF PIRSF016578 5 393 3.3E-73 T 06-07-2017 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 SUPERFAMILY SSF47203 227 391 4.03E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 Gene3D G3DSA:1.10.540.10 8 116 1.6E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 373 2.3E-22 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 Gene3D G3DSA:2.40.110.10 124 207 5.1E-22 T 06-07-2017 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 102 5.2E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS14860 7a2703ccff5bc6d9fab4d002b4102ad5 393 SUPERFAMILY SSF56645 13 213 1.96E-22 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS22970 5e347f47bd461ea188467506b2634b15 187 SUPERFAMILY SSF55194 6 186 1.96E-69 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK95_RS22970 5e347f47bd461ea188467506b2634b15 187 Gene3D G3DSA:1.10.132.20 68 187 3.6E-43 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK95_RS22970 5e347f47bd461ea188467506b2634b15 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 187 1.5E-65 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAK95_RS22970 5e347f47bd461ea188467506b2634b15 187 Pfam PF01765 Ribosome recycling factor 22 185 6.5E-62 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK95_RS22970 5e347f47bd461ea188467506b2634b15 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 26.027 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Pfam PF00072 Response regulator receiver domain 5 116 3.6E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Pfam PF00072 Response regulator receiver domain 158 269 3.0E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Gene3D G3DSA:3.40.50.2300 3 129 1.4E-44 T 06-07-2017 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Gene3D G3DSA:3.40.50.2300 153 282 9.7E-25 T 06-07-2017 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SUPERFAMILY SSF52172 2 133 2.42E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Gene3D G3DSA:3.30.70.270 294 453 7.3E-59 T 06-07-2017 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SMART SM00448 156 268 2.0E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SMART SM00448 3 116 3.2E-45 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SUPERFAMILY SSF52172 151 286 7.26E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SUPERFAMILY SSF55073 297 453 1.49E-51 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 Pfam PF00990 Diguanylate cyclase, GGDEF domain 292 451 1.9E-54 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 454 4.1E-59 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS22030 fa7496e0b49fb179b5341d0e0e8832c5 457 SMART SM00267 278 455 2.8E-64 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 TIGRFAM TIGR00510 lipA: lipoyl synthase 24 310 3.5E-111 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 SUPERFAMILY SSF102114 43 305 2.09E-61 T 06-07-2017 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 18 64 2.0E-6 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 Gene3D G3DSA:3.20.20.70 45 311 2.1E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 SMART SM00729 75 283 7.8E-8 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 PIRSF PIRSF005963 5 318 6.1E-131 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 151.376 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS23225 88869671fff3b37968ac11a0ac49cf28 318 Pfam PF04055 Radical SAM superfamily 82 241 1.5E-10 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 SUPERFAMILY SSF47413 35 99 1.42E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 Gene3D G3DSA:1.10.260.40 31 97 1.2E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 Hamap MF_00109 Shikimate kinase [aroK]. 141 308 20.341 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 Pfam PF01202 Shikimate kinase 150 299 2.1E-30 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 Gene3D G3DSA:3.40.50.300 142 308 1.0E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 SUPERFAMILY SSF52540 143 304 3.2E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 PRINTS PR01100 Shikimate kinase family signature 196 204 1.5E-12 T 06-07-2017 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 PRINTS PR01100 Shikimate kinase family signature 144 159 1.5E-12 T 06-07-2017 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 PRINTS PR01100 Shikimate kinase family signature 168 181 1.5E-12 T 06-07-2017 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 PRINTS PR01100 Shikimate kinase family signature 215 224 1.5E-12 T 06-07-2017 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 Pfam PF01381 Helix-turn-helix 43 93 1.3E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS09720 9c71a2633a85e74e0736ed04c5ea672d 311 SMART SM00530 41 96 3.0E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 SUPERFAMILY SSF48300 3 61 2.49E-15 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 Gene3D G3DSA:1.20.5.710 5 50 8.5E-18 T 06-07-2017 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 1.5E-29 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 2.0E-23 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 125 24.162 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 Gene3D G3DSA:3.30.1390.10 54 125 7.6E-33 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 1.0E-46 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 SUPERFAMILY SSF54736 54 125 2.79E-24 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS21215 8295ddbf160960dd85e7798f7b083ecc 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 50 3.4E-19 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SMART SM00116 170 218 4.3E-6 T 06-07-2017 IPR000644 CBS domain CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SMART SM00116 104 157 9.3E-13 T 06-07-2017 IPR000644 CBS domain CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 307 319 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 499 83.332 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SUPERFAMILY SSF51412 229 490 9.16E-122 T 06-07-2017 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SUPERFAMILY SSF51412 14 98 9.16E-122 T 06-07-2017 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SUPERFAMILY SSF54631 101 218 1.06E-29 T 06-07-2017 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 3.9E-195 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 SMART SM01240 15 486 0.0 T 06-07-2017 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 486 1.6E-158 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 PIRSF PIRSF000130 6 500 3.8E-201 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 Gene3D G3DSA:3.20.20.70 14 497 2.4E-201 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 Pfam PF00571 CBS domain 101 154 1.7E-10 T 06-07-2017 IPR000644 CBS domain CAK95_RS26300 3e0dcd8e45808a49c847612290b8a6d6 501 Pfam PF00571 CBS domain 162 217 1.5E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 SUPERFAMILY SSF56003 123 771 9.55E-181 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 130 4.7E-11 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 177 280 1.7E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 SUPERFAMILY SSF54665 10 152 1.03E-31 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 120 176 1.3E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 284 361 1.3E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 454 620 9.3E-46 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.90.1170.50 11 119 3.1E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 147 707 1.1E-158 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 SMART SM01008 26 131 2.8E-27 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 622 771 8.7E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27785 459683f9b28b5e48d5acd99c969925e0 776 Gene3D G3DSA:3.30.365.10 366 453 8.7E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PIRSF PIRSF002111 1 544 9.9E-193 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 110 180 1.0E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 455 531 1.4E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 442 544 1.39E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 27 95 4.6E-9 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 370 442 2.4E-21 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 283 355 8.4E-23 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 458 530 9.7E-14 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 111 179 1.2E-4 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SMART SM00316 198 268 9.5E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 355 445 1.29E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 288 363 8.8E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 29 109 2.8E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 197 284 3.04E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 263 371 2.5E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 197 268 8.2E-22 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 457 530 2.0E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 287 355 1.4E-19 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 370 442 8.1E-19 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 28 94 2.1E-8 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Pfam PF00575 S1 RNA binding domain 111 179 4.0E-10 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 111 193 2.03E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 29 47 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 220 241 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 163 183 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 47 61 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 134 151 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 116 132 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 92 111 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 298 317 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 PRINTS PR00681 Ribosomal protein S1 signature 338 356 1.5E-81 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 11 530 1.9E-190 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 183 272 2.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 Gene3D G3DSA:2.40.50.140 364 444 3.2E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10935 dd07e44acc0c0916c59ef829bac40a92 571 SUPERFAMILY SSF50249 16 120 2.16E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 357 5.5E-63 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 SUPERFAMILY SSF50615 8 83 2.22E-25 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 PIRSF PIRSF039072 1 480 1.6E-282 T 06-07-2017 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 SMART SM00382 150 334 2.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Gene3D G3DSA:2.40.10.170 8 82 2.7E-34 T 06-07-2017 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Gene3D G3DSA:1.10.1140.10 360 479 2.7E-55 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 10 475 56.95 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 SUPERFAMILY SSF47917 360 475 2.07E-52 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 SUPERFAMILY SSF52540 85 363 8.07E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Gene3D G3DSA:3.40.50.300 85 359 1.4E-109 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 15 81 3.3E-22 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07370 52d035f1cf66a54117c0459014645616 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 12 475 9.6E-251 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAK95_RS26510 3f47cc072eb9c04b10aa05a5d63604f8 346 Pfam PF00561 alpha/beta hydrolase fold 64 188 1.7E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS26510 3f47cc072eb9c04b10aa05a5d63604f8 346 Gene3D G3DSA:3.40.50.1820 31 341 1.3E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS26510 3f47cc072eb9c04b10aa05a5d63604f8 346 SUPERFAMILY SSF53474 15 341 2.48E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Pfam PF01321 Creatinase/Prolidase N-terminal domain 21 153 1.4E-19 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Pfam PF16188 C-terminal region of peptidase_M24 549 608 2.2E-23 T 06-07-2017 IPR032416 Peptidase M24, C-terminal domain CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Gene3D G3DSA:3.40.350.10 184 311 4.5E-7 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Gene3D G3DSA:3.40.350.10 20 150 1.7E-20 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Gene3D G3DSA:3.90.230.10 316 575 2.5E-64 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Pfam PF00557 Metallopeptidase family M24 327 536 1.7E-50 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 SUPERFAMILY SSF53092 183 254 2.79E-6 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 Pfam PF16189 Creatinase/Prolidase N-terminal domain 163 322 6.3E-35 T 06-07-2017 CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 SUPERFAMILY SSF55920 319 574 1.83E-62 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS01715 c629ba90420a7f7a66e50c0c43c3c6e0 611 SUPERFAMILY SSF53092 15 143 5.93E-12 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 107 177 3.4E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 283 357 3.4E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 178 280 2.7E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 681 2.9E-133 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 360 437 4.0E-52 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 599 744 4.0E-52 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 SUPERFAMILY SSF56003 110 743 5.63E-162 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 SUPERFAMILY SSF54665 4 139 7.85E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.90.1170.50 4 106 1.1E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 118 9.9E-29 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 Gene3D G3DSA:3.30.365.10 438 581 2.4E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14160 c6df49451aacb5cf1d5c30b0abadbbfd 745 SMART SM01008 12 118 7.6E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 SUPERFAMILY SSF54373 175 275 2.79E-43 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 SUPERFAMILY SSF51905 274 389 5.44E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 SUPERFAMILY SSF51905 1 172 5.44E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 Pfam PF01494 FAD binding domain 2 342 6.6E-78 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 2.4E-205 T 06-07-2017 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 Gene3D G3DSA:3.30.9.10 153 299 1.9E-62 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.4E-27 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.4E-27 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 3.4E-27 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.4E-27 T 06-07-2017 CAK95_RS25345 db7de90ef0b8f9d51136a8cc231b216b 390 Gene3D G3DSA:3.50.50.60 2 152 2.1E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 PIRSF PIRSF000451 2 350 1.2E-110 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 SUPERFAMILY SSF53901 4 207 1.18E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 221 323 5.3E-15 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 SUPERFAMILY SSF53901 192 347 3.14E-33 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 Gene3D G3DSA:3.40.47.10 5 206 1.3E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 Gene3D G3DSA:3.40.47.10 211 348 1.9E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS15410 89d6eca129fb4a29f890d321b76a89e8 350 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 71 204 3.3E-22 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 1.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.0E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 Gene3D G3DSA:3.40.50.1820 15 266 3.6E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 SUPERFAMILY SSF53474 15 265 7.19E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08785 c1dbc9a41ca25f02db715a24a2ab252f 267 Pfam PF12146 Serine aminopeptidase, S33 28 234 4.8E-21 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 Gene3D G3DSA:3.30.1370.30 3 73 4.2E-23 T 06-07-2017 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 Pfam PF00410 Ribosomal protein S8 5 132 7.2E-47 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 Gene3D G3DSA:3.30.1490.10 76 132 9.6E-27 T 06-07-2017 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 SUPERFAMILY SSF56047 3 132 2.49E-42 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21335 da3dc969ecafb843ce1a77bf878e9920 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.345 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21635 45d3aa5053770389133f96c8cbffbedf 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 313 1.2E-42 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS21635 45d3aa5053770389133f96c8cbffbedf 338 SUPERFAMILY SSF53850 135 260 3.97E-5 T 06-07-2017 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Pfam PF13414 TPR repeat 164 204 1.5E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Pfam PF13649 Methyltransferase domain 547 636 1.8E-6 T 06-07-2017 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Pfam PF13431 Tetratricopeptide repeat 214 245 1.9E-5 T 06-07-2017 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Gene3D G3DSA:3.40.50.150 548 642 3.4E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SUPERFAMILY SSF48452 25 256 4.93E-37 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 224 257 30.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 88 121 2.4E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 156 189 0.012 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 190 223 1.4E-6 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 54 87 31.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SMART SM00028 122 155 0.0018 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Pfam PF13432 Tetratricopeptide repeat 92 156 1.5E-9 T 06-07-2017 CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 SUPERFAMILY SSF53335 538 731 4.55E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS28440 67a6781074b16ccc1fd2d0c9590e162d 782 Gene3D G3DSA:1.25.40.10 21 253 7.3E-58 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS22865 963ad97e72baaf763d3cf06ca8969de2 341 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 217 230 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22865 963ad97e72baaf763d3cf06ca8969de2 341 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 336 24.112 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22865 963ad97e72baaf763d3cf06ca8969de2 341 Pfam PF00146 NADH dehydrogenase 20 329 1.1E-119 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 9.7E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 260 278 9.7E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 89 9.7E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 9.7E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 Gene3D G3DSA:3.40.50.2300 32 231 4.7E-48 T 06-07-2017 CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 SUPERFAMILY SSF53822 32 388 7.74E-72 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS14320 ee91ff0d00053225392704a5188c1607 397 Pfam PF13458 Periplasmic binding protein 32 356 5.2E-58 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 SUPERFAMILY SSF55424 330 401 1.7E-15 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 SUPERFAMILY SSF51905 122 257 2.78E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 332 400 2.1E-17 T 06-07-2017 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 SUPERFAMILY SSF51905 11 115 6.89E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 SUPERFAMILY SSF51905 251 327 6.89E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Gene3D G3DSA:3.50.50.60 12 123 3.5E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Gene3D G3DSA:3.50.50.60 258 328 3.5E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 123 2.5E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Gene3D G3DSA:3.90.760.10 331 401 4.3E-19 T 06-07-2017 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CAK95_RS15010 8f9761b62e328da7b397529648d15599 401 Gene3D G3DSA:3.50.50.60 126 257 7.2E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 Pfam PF03466 LysR substrate binding domain 91 295 9.5E-50 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 Gene3D G3DSA:1.10.10.10 9 91 1.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 Gene3D G3DSA:3.40.190.10 180 270 3.8E-23 T 06-07-2017 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 SUPERFAMILY SSF53850 93 297 1.06E-47 T 06-07-2017 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 SUPERFAMILY SSF46785 9 115 7.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 Gene3D G3DSA:3.40.190.10 93 179 9.3E-22 T 06-07-2017 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08695 2b2a4815ae5b945805b94029c29c132f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Gene3D G3DSA:3.40.190.10 29 135 1.9E-44 T 06-07-2017 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 28 322 36.763 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 SUPERFAMILY SSF54782 246 328 1.02E-21 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Gene3D G3DSA:3.30.160.40 246 327 1.6E-20 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 SUPERFAMILY SSF53850 28 243 5.07E-78 T 06-07-2017 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PRINTS PR00151 Porphobilinogen deaminase signature 101 120 1.4E-41 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PRINTS PR00151 Porphobilinogen deaminase signature 70 90 1.4E-41 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PRINTS PR00151 Porphobilinogen deaminase signature 149 166 1.4E-41 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PRINTS PR00151 Porphobilinogen deaminase signature 168 185 1.4E-41 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PRINTS PR00151 Porphobilinogen deaminase signature 255 272 1.4E-41 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 256 272 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Gene3D G3DSA:3.40.190.10 136 224 3.5E-35 T 06-07-2017 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 29 321 3.1E-107 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 29 237 1.1E-74 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 252 320 7.7E-15 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08445 3506a2f01ae8d35260ac95240a829c5b 331 PIRSF PIRSF001438 6 331 2.6E-114 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS26135 ba28e528c54599133c34f7e0f57c9c5b 356 SUPERFAMILY SSF56235 12 341 1.47E-96 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS26135 ba28e528c54599133c34f7e0f57c9c5b 356 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 12 334 4.5E-79 T 06-07-2017 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CAK95_RS26135 ba28e528c54599133c34f7e0f57c9c5b 356 Gene3D G3DSA:3.60.60.10 12 348 3.7E-112 T 06-07-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 SUPERFAMILY SSF52833 18 190 3.24E-54 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 PIRSF PIRSF000216 3 226 1.7E-64 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 129 147 - T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 29 171 1.6E-54 T 06-07-2017 CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 29 171 7.0E-51 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22850 4d8edee94a6428b23b5079ee9cf7a086 248 Gene3D G3DSA:3.40.30.10 93 177 8.2E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82866 291 490 2.49E-50 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:3.30.2090.10 705 793 5.7E-14 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 7.7E-76 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82693 40 134 2.09E-23 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:3.30.70.1430 40 141 4.4E-29 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:3.30.2090.10 182 262 2.3E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:1.10.3850.10 275 491 1.2E-58 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:1.10.3850.10 796 1013 2.8E-48 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82693 556 652 3.4E-12 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82714 706 789 2.35E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82714 183 262 2.22E-16 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82693 136 182 3.4E-21 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82693 268 324 3.4E-21 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Gene3D G3DSA:3.30.70.1430 559 646 6.1E-6 T 06-07-2017 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 Pfam PF00873 AcrB/AcrD/AcrF family 5 1011 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS15495 863b95e8554ddd0902de8f780e2bdf9e 1034 SUPERFAMILY SSF82866 790 1017 3.01E-39 T 06-07-2017 CAK95_RS10110 5bc7c1170095669bffb501701e20f513 239 SMART SM00382 29 215 6.3E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10110 5bc7c1170095669bffb501701e20f513 239 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS10110 5bc7c1170095669bffb501701e20f513 239 Pfam PF00005 ABC transporter 20 166 2.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10110 5bc7c1170095669bffb501701e20f513 239 Gene3D G3DSA:3.40.50.300 4 233 8.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10110 5bc7c1170095669bffb501701e20f513 239 SUPERFAMILY SSF52540 4 233 2.66E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 4.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 SUPERFAMILY SSF46785 20 92 1.72E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 Pfam PF07729 FCD domain 113 233 5.2E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 Gene3D G3DSA:1.10.10.10 17 88 5.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 SUPERFAMILY SSF48008 111 238 1.07E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 Gene3D G3DSA:1.20.120.530 111 238 1.2E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 SMART SM00895 113 234 1.1E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 8.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 8.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS09985 9023801ba06abdc45423e8255761ba60 251 SMART SM00345 27 88 9.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 SUPERFAMILY SSF51735 7 258 5.0E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 258 4.8E-49 T 06-07-2017 CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 Gene3D G3DSA:3.40.50.720 2 257 1.5E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16340 892df075000eb3ce4ea3284ed317fd1f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Gene3D G3DSA:3.10.20.30 222 317 4.2E-23 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 SUPERFAMILY SSF63380 12 104 1.29E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Pfam PF00175 Oxidoreductase NAD-binding domain 118 210 6.2E-9 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Pfam PF00970 Oxidoreductase FAD-binding domain 13 107 1.8E-7 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 SUPERFAMILY SSF54292 216 316 4.59E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 SUPERFAMILY SSF52343 102 231 2.75E-27 T 06-07-2017 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Gene3D G3DSA:2.40.30.10 10 105 2.9E-29 T 06-07-2017 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 249 313 2.5E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 Gene3D G3DSA:3.40.50.80 112 221 2.5E-25 T 06-07-2017 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 34 44 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 143 152 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 44 56 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 94 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 136 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 196 204 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 56 70 3.1E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS02250 63a2bd63d07b3d061bed25d57be030f1 322 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 273 281 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS08040 b3ae974f1ea75a0001caef5523767b26 231 SMART SM00978 83 229 7.1E-61 T 06-07-2017 IPR007379 Tim44-like domain CAK95_RS08040 b3ae974f1ea75a0001caef5523767b26 231 Pfam PF04280 Tim44-like domain 84 228 1.1E-52 T 06-07-2017 IPR007379 Tim44-like domain CAK95_RS08040 b3ae974f1ea75a0001caef5523767b26 231 ProDom PD111165 RP434 19 228 1.0E-5 T 06-07-2017 CAK95_RS08040 b3ae974f1ea75a0001caef5523767b26 231 PIRSF PIRSF031890 1 231 8.1E-92 T 06-07-2017 IPR016985 Uncharacterised conserved protein UCP031890, Tim44-related CAK95_RS08040 b3ae974f1ea75a0001caef5523767b26 231 SUPERFAMILY SSF54427 70 228 5.55E-56 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Gene3D G3DSA:3.10.20.30 6 78 8.0E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 67 1.7E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 SUPERFAMILY SSF54292 6 90 3.93E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Gene3D G3DSA:1.10.150.120 79 159 1.3E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 218 353 4.0E-11 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Pfam PF01799 [2Fe-2S] binding domain 77 149 1.2E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 SUPERFAMILY SSF55961 217 355 5.5E-19 T 06-07-2017 CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 Gene3D G3DSA:3.30.530.20 210 357 4.0E-25 T 06-07-2017 IPR023393 START-like domain CAK95_RS25535 1ed374e4e3e2c24d97f7e471b9f75be4 384 SUPERFAMILY SSF47741 88 155 2.09E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Pfam PF01769 Divalent cation transporter 338 460 7.6E-28 T 06-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SMART SM00116 161 214 0.83 T 06-07-2017 IPR000644 CBS domain CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SMART SM00116 225 273 1.7E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 TIGRFAM TIGR00400 mgtE: magnesium transporter 44 464 1.0E-96 T 06-07-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Gene3D G3DSA:3.10.580.10 153 274 1.5E-20 T 06-07-2017 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Pfam PF00571 CBS domain 220 272 4.3E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Pfam PF00571 CBS domain 158 211 1.1E-4 T 06-07-2017 IPR000644 CBS domain CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Gene3D G3DSA:1.25.60.10 21 148 8.4E-26 T 06-07-2017 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SUPERFAMILY SSF54631 154 291 1.04E-31 T 06-07-2017 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SUPERFAMILY SSF158791 25 151 8.11E-26 T 06-07-2017 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Pfam PF03448 MgtE intracellular N domain 51 152 1.0E-19 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 Gene3D G3DSA:1.10.357.20 295 466 1.1E-53 T 06-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SUPERFAMILY SSF161093 294 466 4.58E-49 T 06-07-2017 CAK95_RS21725 3edffaf2a57bd3b402c446f9c514104a 469 SMART SM00924 51 154 1.9E-25 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 182 289 1.5E-23 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 462 641 2.0E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 SUPERFAMILY SSF54665 7 143 7.98E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25410 fba664a32826921456d1bb085e616333 985 SUPERFAMILY SSF56003 130 802 3.66E-167 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 741 1.1E-146 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 656 800 9.9E-56 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 369 461 9.9E-56 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 SUPERFAMILY SSF55961 827 967 9.24E-36 T 06-07-2017 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 292 367 1.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.365.10 128 181 1.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 27 138 3.2E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25410 fba664a32826921456d1bb085e616333 985 SMART SM01008 27 138 2.3E-48 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 829 967 1.0E-27 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.30.530.20 828 970 1.3E-42 T 06-07-2017 IPR023393 START-like domain CAK95_RS25410 fba664a32826921456d1bb085e616333 985 Gene3D G3DSA:3.90.1170.50 6 127 8.9E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 SUPERFAMILY SSF63380 128 255 2.27E-35 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PIRSF PIRSF000361 100 400 1.5E-71 T 06-07-2017 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Pfam PF00037 4Fe-4S binding domain 16 37 1.3E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 12 400 4.0E-179 T 06-07-2017 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Gene3D G3DSA:3.30.70.20 15 66 9.3E-15 T 06-07-2017 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Gene3D G3DSA:3.40.50.80 249 399 1.0E-35 T 06-07-2017 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PIRSF PIRSF501177 1 400 4.1E-196 T 06-07-2017 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Pfam PF00970 Oxidoreductase FAD-binding domain 192 248 3.4E-7 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 SUPERFAMILY SSF52343 250 400 3.27E-35 T 06-07-2017 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 SUPERFAMILY SSF54862 15 70 1.7E-17 T 06-07-2017 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Gene3D G3DSA:2.40.30.10 125 246 2.3E-36 T 06-07-2017 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 330 346 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 197 204 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 288 297 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 354 362 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 225 234 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 261 280 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 174 184 1.4E-20 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS09740 faa6fd8b0799179c55c303436581387f 400 Pfam PF00175 Oxidoreductase NAD-binding domain 262 368 9.2E-16 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 SUPERFAMILY SSF47616 69 193 2.78E-21 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 71 2.0E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 Gene3D G3DSA:1.20.1050.10 80 195 1.4E-24 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 SUPERFAMILY SSF52833 1 82 3.05E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 Gene3D G3DSA:3.40.30.10 1 79 9.7E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS24285 31c168bc94455cec612f03019deb99e4 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 128 187 2.7E-5 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS21555 3edc187ef129d5de917f8c289979b48c 182 Gene3D G3DSA:1.10.357.10 10 160 5.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS21555 3edc187ef129d5de917f8c289979b48c 182 SUPERFAMILY SSF46689 8 85 7.83E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS21555 3edc187ef129d5de917f8c289979b48c 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 8.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS21555 3edc187ef129d5de917f8c289979b48c 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 8.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS21555 3edc187ef129d5de917f8c289979b48c 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 4.9E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS10835 30214d6246cf166d3dc7e5ff095716cb 377 SUPERFAMILY SSF102114 3 287 7.46E-41 T 06-07-2017 CAK95_RS10835 30214d6246cf166d3dc7e5ff095716cb 377 Pfam PF13186 Iron-sulfur cluster-binding domain 230 288 2.1E-7 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain CAK95_RS10835 30214d6246cf166d3dc7e5ff095716cb 377 Pfam PF04055 Radical SAM superfamily 6 156 3.2E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS10835 30214d6246cf166d3dc7e5ff095716cb 377 Gene3D G3DSA:3.20.20.70 5 289 1.4E-42 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS10835 30214d6246cf166d3dc7e5ff095716cb 377 SMART SM00729 1 191 0.0073 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 SUPERFAMILY SSF46689 286 338 7.43E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 Pfam PF14525 AraC-binding-like domain 40 213 5.0E-7 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 287 332 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 Gene3D G3DSA:1.10.10.60 285 338 5.0E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 SMART SM00342 251 336 2.7E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 Pfam PF12833 Helix-turn-helix domain 258 337 3.3E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 305 320 6.0E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS20530 0b7fff28d2a3a9a2f4cb2d2007331055 340 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 320 336 6.0E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS18685 63f611b5917de5181db0be482fe9f482 256 Gene3D G3DSA:3.90.550.10 13 218 3.6E-16 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS18685 63f611b5917de5181db0be482fe9f482 256 SUPERFAMILY SSF53448 9 225 1.5E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS18685 63f611b5917de5181db0be482fe9f482 256 Pfam PF00535 Glycosyl transferase family 2 15 93 2.0E-14 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS18685 63f611b5917de5181db0be482fe9f482 256 TIGRFAM TIGR04283 glyco_like_mftF: transferase 2, rSAM/selenodomain-associated 14 234 1.8E-67 T 06-07-2017 IPR026461 Transferase 2, rSAM/selenodomain-associated CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 Gene3D G3DSA:3.40.50.180 156 345 4.3E-78 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 PIRSF PIRSF000876 2 349 7.0E-136 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 5 345 39.765 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 SUPERFAMILY SSF52738 159 346 2.35E-68 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 Pfam PF00072 Response regulator receiver domain 7 112 4.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 SMART SM00448 5 128 3.3E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 SUPERFAMILY SSF52172 4 111 4.7E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 Pfam PF01339 CheB methylesterase 162 340 6.2E-60 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAK95_RS06055 8866ddacfc63a905e5514b754cfd0a6e 360 Gene3D G3DSA:3.40.50.2300 4 135 5.8E-30 T 06-07-2017 CAK95_RS22615 2173a485993c2a3b267c2f7967d388b3 360 Pfam PF02628 Cytochrome oxidase assembly protein 14 334 8.0E-111 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CAK95_RS22615 2173a485993c2a3b267c2f7967d388b3 360 Hamap MF_01665 Heme A synthase [ctaA]. 10 344 25.995 T 06-07-2017 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 Gene3D G3DSA:2.60.40.420 113 227 1.5E-34 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 Pfam PF00034 Cytochrome c 240 329 1.0E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 SUPERFAMILY SSF49503 112 274 3.47E-43 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 139 214 5.1E-19 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 162 210 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 Gene3D G3DSA:1.10.760.10 228 328 2.4E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11620 1cc0d4eca646c62f101453bedc5deb11 329 SUPERFAMILY SSF46626 240 328 1.72E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS09705 c6d26a8bebec0dc7ce426f91fc2a7313 211 SUPERFAMILY SSF53335 7 195 2.54E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09705 c6d26a8bebec0dc7ce426f91fc2a7313 211 Gene3D G3DSA:3.40.50.150 3 192 3.4E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09705 c6d26a8bebec0dc7ce426f91fc2a7313 211 Pfam PF13489 Methyltransferase domain 30 191 7.4E-19 T 06-07-2017 CAK95_RS08735 09afb1c8376146db6f1c6c79685b08a3 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 94 4.2E-31 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK95_RS08735 09afb1c8376146db6f1c6c79685b08a3 97 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 95 24.661 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK95_RS08735 09afb1c8376146db6f1c6c79685b08a3 97 Gene3D G3DSA:3.30.1360.20 2 95 3.6E-35 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK95_RS08735 09afb1c8376146db6f1c6c79685b08a3 97 SUPERFAMILY SSF55248 2 95 9.42E-35 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK95_RS26285 881e456d98b18e36a4f643c0bd12285c 142 SUPERFAMILY SSF161084 4 130 1.8E-21 T 06-07-2017 CAK95_RS26285 881e456d98b18e36a4f643c0bd12285c 142 Gene3D G3DSA:1.20.120.550 5 136 3.9E-12 T 06-07-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CAK95_RS26285 881e456d98b18e36a4f643c0bd12285c 142 Pfam PF01124 MAPEG family 7 131 1.5E-16 T 06-07-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Gene3D G3DSA:1.10.150.120 84 169 6.8E-34 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 PIRSF PIRSF036557 1 468 1.9E-162 T 06-07-2017 IPR012175 Xanthine dehydrogenase, small subunit, bacteria CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 SUPERFAMILY SSF55447 356 460 6.28E-28 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 SUPERFAMILY SSF54292 3 87 5.76E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 SUPERFAMILY SSF56176 180 349 9.0E-51 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 SUPERFAMILY SSF47741 94 197 2.88E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 4 457 5.4E-163 T 06-07-2017 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 186 349 7.6E-48 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 SMART SM01092 357 458 3.6E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Pfam PF01799 [2Fe-2S] binding domain 82 155 1.8E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Gene3D G3DSA:3.30.465.10 237 349 1.9E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 358 454 1.9E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Gene3D G3DSA:3.30.43.10 188 235 3.8E-14 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Gene3D G3DSA:3.30.390.50 358 458 3.3E-31 T 06-07-2017 CAK95_RS10025 c62ae46d604705133419117ce28030c9 470 Gene3D G3DSA:3.10.20.30 3 83 1.9E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS02470 2db0392a311a96fb7903f7e02618386a 579 Pfam PF11843 Protein of unknown function (DUF3363) 278 402 6.0E-35 T 06-07-2017 IPR021795 Protein of unknown function DUF3363 CAK95_RS02470 2db0392a311a96fb7903f7e02618386a 579 Pfam PF11843 Protein of unknown function (DUF3363) 399 578 2.1E-61 T 06-07-2017 IPR021795 Protein of unknown function DUF3363 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 SUPERFAMILY SSF52402 10 175 1.85E-46 T 06-07-2017 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 Pfam PF00764 Arginosuccinate synthase 13 403 1.1E-152 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 SUPERFAMILY SSF69864 182 410 1.57E-90 T 06-07-2017 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 125 136 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 Gene3D G3DSA:3.40.50.620 10 179 1.3E-63 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 15 23 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 Gene3D G3DSA:3.90.1260.10 185 411 9.1E-97 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 Hamap MF_00005 Argininosuccinate synthase [argG]. 9 409 51.696 T 06-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS07970 24dfc2eb75a5bb713fdc4ded1ca84660 413 TIGRFAM TIGR00032 argG: argininosuccinate synthase 11 408 1.5E-141 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 Gene3D G3DSA:3.40.50.7700 10 175 1.3E-70 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 PIRSF PIRSF001338 14 179 6.4E-64 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 Pfam PF00731 AIR carboxylase 19 165 6.7E-61 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 19 172 31.489 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 SMART SM01001 17 168 1.2E-93 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 19 174 4.4E-61 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS04370 2f9369e327ebfb264149a508fe7f3a99 183 SUPERFAMILY SSF52255 18 175 3.14E-63 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK95_RS24845 e5b0b512c858813586ff8166bfc7acb4 173 Pfam PF09335 SNARE associated Golgi protein 39 163 1.4E-16 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82866 295 490 3.79E-37 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82693 271 326 5.06E-18 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82693 139 185 5.06E-18 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Pfam PF00873 AcrB/AcrD/AcrF family 7 1012 2.3E-156 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:1.10.3850.10 277 489 4.9E-46 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:1.10.3850.10 803 1015 6.8E-52 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82714 188 269 1.44E-10 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:3.30.70.1430 43 138 2.5E-18 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82693 561 646 1.33E-5 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:3.30.2090.10 188 270 3.8E-12 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:3.30.2090.10 711 797 2.0E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82714 712 797 4.84E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 9.0E-23 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 9.0E-23 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 9.0E-23 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 9.0E-23 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 9.0E-23 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82866 794 1017 3.4E-45 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 Gene3D G3DSA:3.30.70.1430 562 652 7.0E-4 T 06-07-2017 CAK95_RS00780 d8a6d2d9adfa10818d559fd15605a3d7 1044 SUPERFAMILY SSF82693 43 136 2.09E-16 T 06-07-2017 CAK95_RS14755 82e020ea9b07b6c793d7a8fe7f66df11 263 Gene3D G3DSA:1.10.3720.10 53 251 8.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14755 82e020ea9b07b6c793d7a8fe7f66df11 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 2.4E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14755 82e020ea9b07b6c793d7a8fe7f66df11 263 SUPERFAMILY SSF161098 58 241 6.41E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21030 2fa24f6591fb54663c9bc4a0c546be6d 516 Gene3D G3DSA:3.90.1300.10 41 509 1.7E-114 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS21030 2fa24f6591fb54663c9bc4a0c546be6d 516 Pfam PF01425 Amidase 59 496 1.1E-86 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS21030 2fa24f6591fb54663c9bc4a0c546be6d 516 SUPERFAMILY SSF75304 41 509 1.7E-106 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 SUPERFAMILY SSF52151 49 122 6.02E-53 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 SUPERFAMILY SSF52151 163 389 6.02E-53 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 Pfam PF12536 Patatin phospholipase 293 396 6.1E-35 T 06-07-2017 IPR021095 Protein of unknown function DUF3734 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 Gene3D G3DSA:3.40.1090.10 157 253 7.9E-6 T 06-07-2017 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 Gene3D G3DSA:3.40.1090.10 52 122 7.9E-6 T 06-07-2017 CAK95_RS21750 6d539c1cf2609b1b4d1a79e53f4d2880 412 Pfam PF01734 Patatin-like phospholipase 52 255 6.6E-25 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 Gene3D G3DSA:3.40.50.300 1 209 1.1E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 SMART SM00487 20 220 1.7E-65 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 Pfam PF00271 Helicase conserved C-terminal domain 231 340 1.4E-30 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 SMART SM00490 259 340 2.0E-32 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 Pfam PF00270 DEAD/DEAH box helicase 25 193 2.6E-50 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 SUPERFAMILY SSF52540 73 361 9.98E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 Gene3D G3DSA:3.40.50.300 210 372 3.4E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24950 69eca4da3c8d69482c6b3ed32dab0106 453 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAK95_RS21125 2cce0f54257d8b111e683960cff5f4f2 208 Gene3D G3DSA:2.60.130.10 7 207 9.2E-69 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21125 2cce0f54257d8b111e683960cff5f4f2 208 SUPERFAMILY SSF49482 7 208 1.19E-65 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21125 2cce0f54257d8b111e683960cff5f4f2 208 Pfam PF00775 Dioxygenase 46 198 2.9E-19 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21125 2cce0f54257d8b111e683960cff5f4f2 208 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 54 82 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21125 2cce0f54257d8b111e683960cff5f4f2 208 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 11 208 9.3E-80 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 31 270 2.8E-56 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 Gene3D G3DSA:3.10.20.10 32 117 1.1E-25 T 06-07-2017 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 Pfam PF02634 FdhD/NarQ family 31 268 2.1E-70 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 SUPERFAMILY SSF53927 23 268 3.61E-72 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 Gene3D G3DSA:3.40.140.10 136 271 2.6E-45 T 06-07-2017 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 PIRSF PIRSF015626 5 273 8.5E-71 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS12305 0c2978469e1eb3b989ce2eb5975c85c2 277 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 269 30.393 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 47 55 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 SUPERFAMILY SSF54292 10 86 2.23E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 SUPERFAMILY SSF47741 92 157 3.01E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 Pfam PF01799 [2Fe-2S] binding domain 81 152 8.9E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 67 7.2E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 Gene3D G3DSA:3.10.20.30 9 82 1.7E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS27525 6a0115a9943a413ad813a3adc730f3a4 164 Gene3D G3DSA:1.10.150.120 83 159 1.7E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS10165 9d430a444e7d71397e322554cec250bd 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 266 4.5E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10165 9d430a444e7d71397e322554cec250bd 280 Gene3D G3DSA:1.10.3720.10 73 267 1.0E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10165 9d430a444e7d71397e322554cec250bd 280 SUPERFAMILY SSF161098 75 255 1.09E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06135 0353164efced6dd502165da074fcdd5a 369 SUPERFAMILY SSF51726 4 368 2.09E-78 T 06-07-2017 CAK95_RS06135 0353164efced6dd502165da074fcdd5a 369 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 343 4.0E-15 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS06135 0353164efced6dd502165da074fcdd5a 369 Gene3D G3DSA:3.20.20.210 4 369 2.5E-114 T 06-07-2017 CAK95_RS06080 9c186dffef366b8e026254b64a29e131 314 Gene3D G3DSA:3.10.180.10 4 131 2.6E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS06080 9c186dffef366b8e026254b64a29e131 314 Gene3D G3DSA:3.10.180.10 143 312 5.2E-40 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS06080 9c186dffef366b8e026254b64a29e131 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 273 5.2E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS06080 9c186dffef366b8e026254b64a29e131 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 130 4.4E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS06080 9c186dffef366b8e026254b64a29e131 314 SUPERFAMILY SSF54593 5 285 2.69E-51 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 06-07-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 Gene3D G3DSA:3.10.20.30 1 102 8.3E-39 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 PRINTS PR00355 Adrenodoxin signature 59 73 3.6E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 PRINTS PR00355 Adrenodoxin signature 82 90 3.6E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 PRINTS PR00355 Adrenodoxin signature 40 50 3.6E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 SUPERFAMILY SSF54292 3 104 1.76E-33 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS17985 fb99c9a7ae0421cd4a5c2bf3a0e9c557 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 90 1.7E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 Pfam PF00293 NUDIX domain 11 157 8.7E-23 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 SUPERFAMILY SSF55811 4 165 7.58E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 Gene3D G3DSA:3.90.79.10 7 163 2.3E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 5 167 32.457 T 06-07-2017 IPR022927 RNA pyrophosphohydrolase RppH CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 PRINTS PR00502 NUDIX hydrolase family signature 58 73 3.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS07355 a4e36a21c9b4ce8655e51e1ef969933f 167 PRINTS PR00502 NUDIX hydrolase family signature 44 58 3.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 Gene3D G3DSA:1.10.10.10 1 86 3.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 Gene3D G3DSA:3.40.190.10 91 190 4.2E-11 T 06-07-2017 CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 SUPERFAMILY SSF53850 89 287 5.61E-21 T 06-07-2017 CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 Pfam PF03466 LysR substrate binding domain 88 286 5.9E-18 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 SUPERFAMILY SSF46785 1 110 3.04E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22040 cf904926e9529f7c4fcdf4864eb2971f 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 ProSitePatterns PS00455 Putative AMP-binding domain signature. 236 247 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 SUPERFAMILY SSF56801 30 610 8.63E-74 T 06-07-2017 CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 Gene3D G3DSA:2.30.38.10 415 475 1.8E-9 T 06-07-2017 CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 Pfam PF00501 AMP-binding enzyme 68 495 3.5E-56 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 Gene3D G3DSA:3.40.50.980 242 405 1.2E-19 T 06-07-2017 CAK95_RS26355 9a7d5077f57e41a681818b033f5e46b8 619 Gene3D G3DSA:3.40.50.980 63 241 1.1E-22 T 06-07-2017 CAK95_RS20345 63e7f33a8d90aa1a2093996a3add6dae 215 Gene3D G3DSA:3.20.20.370 5 185 4.3E-32 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS20345 63e7f33a8d90aa1a2093996a3add6dae 215 SUPERFAMILY SSF88713 5 187 1.47E-31 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS20345 63e7f33a8d90aa1a2093996a3add6dae 215 Pfam PF01522 Polysaccharide deacetylase 4 106 3.2E-16 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS07835 f31b0a701dd2be91c2099f809f653c98 129 SUPERFAMILY SSF81343 15 125 3.92E-24 T 06-07-2017 CAK95_RS07835 f31b0a701dd2be91c2099f809f653c98 129 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7 112 3.9E-14 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07835 f31b0a701dd2be91c2099f809f653c98 129 Gene3D G3DSA:1.20.1300.10 14 124 5.7E-25 T 06-07-2017 CAK95_RS07835 f31b0a701dd2be91c2099f809f653c98 129 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 20 122 1.3E-25 T 06-07-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CAK95_RS17850 3a6874c0a75b71dff797f01eb52e2eff 284 SUPERFAMILY SSF56529 62 281 6.8E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17850 3a6874c0a75b71dff797f01eb52e2eff 284 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 279 2.4E-65 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17850 3a6874c0a75b71dff797f01eb52e2eff 284 Gene3D G3DSA:3.90.850.10 62 280 9.0E-82 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 Gene3D G3DSA:3.30.70.260 18 94 6.0E-34 T 06-07-2017 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 Gene3D G3DSA:3.30.70.1150 101 178 8.0E-31 T 06-07-2017 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 Pfam PF10369 Small subunit of acetolactate synthase 102 175 8.3E-27 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 19 93 4.0E-33 T 06-07-2017 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 SUPERFAMILY SSF55021 98 178 6.87E-26 T 06-07-2017 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 SUPERFAMILY SSF55021 19 93 2.06E-19 T 06-07-2017 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 18 176 1.6E-55 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK95_RS14680 bd84b5791e26f83b28c57335159faf2e 179 Pfam PF01842 ACT domain 19 84 2.1E-13 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 222 307 1.9E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 123 9.6E-35 T 06-07-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 19 457 5.1E-85 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 SUPERFAMILY SSF116878 383 457 6.93E-44 T 06-07-2017 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 SUPERFAMILY SSF116878 124 224 6.93E-44 T 06-07-2017 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Gene3D G3DSA:3.30.1360.120 5 124 8.2E-40 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 457 30.041 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Pfam PF12631 MnmE helical domain 126 454 5.3E-51 T 06-07-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 SUPERFAMILY SSF52540 75 166 8.23E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 SUPERFAMILY SSF52540 201 373 8.23E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Gene3D G3DSA:3.40.50.300 203 243 2.5E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Gene3D G3DSA:1.20.120.430 244 275 1.7E-55 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Gene3D G3DSA:1.20.120.430 388 457 1.7E-55 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Gene3D G3DSA:1.20.120.430 125 185 1.7E-55 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAK95_RS08135 9e6d60f39f8962389cdaff79dd208e8c 457 Pfam PF01926 50S ribosome-binding GTPase 223 312 2.4E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 Pfam PF02934 GatB/GatE catalytic domain 19 301 2.6E-113 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 158 172 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 SUPERFAMILY SSF89095 310 415 1.4E-33 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 487 37.114 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 SUPERFAMILY SSF55931 18 309 5.04E-115 T 06-07-2017 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 SMART SM00845 341 486 2.2E-77 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 Gene3D G3DSA:1.10.10.410 432 486 2.3E-4 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 486 8.5E-163 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAK95_RS23790 1dd90434cffadb3ff6de2cfd02bf4a1a 489 Pfam PF02637 GatB domain 341 486 8.4E-50 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 Gene3D G3DSA:1.20.1560.10 30 362 2.4E-62 T 06-07-2017 CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 Pfam PF00005 ABC transporter 392 541 1.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 SUPERFAMILY SSF52540 365 611 1.36E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 SMART SM00382 401 587 4.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 Gene3D G3DSA:3.40.50.300 375 606 1.9E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 Pfam PF00664 ABC transporter transmembrane region 49 330 7.2E-36 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS20070 ff79c61c08662aebae549a9c331d2c66 660 SUPERFAMILY SSF90123 30 350 5.1E-61 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Pfam PF07498 Rho termination factor, N-terminal domain 8 48 1.2E-16 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 420 5.0E-218 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Pfam PF07497 Rho termination factor, RNA-binding domain 55 128 6.5E-32 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SMART SM00357 55 121 4.2E-20 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SUPERFAMILY SSF50249 51 128 2.6E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Gene3D G3DSA:3.40.50.300 134 419 4.0E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SMART SM00382 173 358 4.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 421 249.726 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Gene3D G3DSA:2.40.50.140 52 119 1.3E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 162 366 5.8E-22 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 Gene3D G3DSA:1.10.720.10 5 48 1.9E-20 T 06-07-2017 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SUPERFAMILY SSF52540 93 374 2.56E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SUPERFAMILY SSF68912 5 47 9.42E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK95_RS08090 6570778adff003cf9b2f64fc4df2b951 421 SMART SM00959 8 50 4.7E-17 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 Gene3D G3DSA:3.30.450.40 127 299 5.4E-48 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 Gene3D G3DSA:1.10.10.10 44 115 1.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 SMART SM00346 54 144 1.3E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 SUPERFAMILY SSF55781 125 300 1.9E-43 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 Pfam PF01614 Bacterial transcriptional regulator 182 295 1.2E-33 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 Pfam PF09339 IclR helix-turn-helix domain 56 106 3.0E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS16620 82cf172eb98b00bdacede198d21ea670 303 SUPERFAMILY SSF46785 54 126 5.75E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 Gene3D G3DSA:2.60.40.180 178 294 1.9E-35 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 Pfam PF09349 OHCU decarboxylase 11 165 1.4E-45 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 15 167 2.4E-56 T 06-07-2017 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 Gene3D G3DSA:1.10.3330.10 12 170 9.1E-55 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 ProSitePatterns PS00769 Transthyretin signature 2. 277 289 - T 06-07-2017 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 Pfam PF00576 HIUase/Transthyretin family 181 293 1.7E-33 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 PRINTS PR00189 Transthyretin signature 180 200 1.6E-6 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 PRINTS PR00189 Transthyretin signature 272 294 1.6E-6 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 SUPERFAMILY SSF49472 174 294 1.01E-37 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 ProSitePatterns PS00768 Transthyretin signature 1. 184 199 - T 06-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 180 294 1.4E-38 T 06-07-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK95_RS18615 7260473d9e21eafd524e22c10aaae3b0 294 SUPERFAMILY SSF158694 6 168 1.44E-50 T 06-07-2017 CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 SUPERFAMILY SSF54593 16 353 1.98E-84 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 PIRSF PIRSF009283 7 367 2.9E-112 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 Gene3D G3DSA:3.10.180.10 15 160 1.5E-47 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 Gene3D G3DSA:3.10.180.10 167 366 1.5E-63 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 170 284 1.9E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 16 152 4.8E-63 T 06-07-2017 CAK95_RS17445 e587ad2013ae123e39d0a64257f12866 375 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 23 366 8.4E-120 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 SUPERFAMILY SSF48179 203 321 4.42E-17 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 325 6.6E-46 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 Gene3D G3DSA:3.40.50.720 3 196 2.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 109 8.0E-22 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 SUPERFAMILY SSF51735 6 116 2.56E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 Gene3D G3DSA:1.10.1040.10 203 323 3.6E-20 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS06385 ebc3e12e7e8c774caac846c7abe92d9a 343 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 203 321 2.8E-20 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS03405 5cffcf97c21b353580afeb8951c7c7ea 443 Pfam PF00239 Resolvase, N terminal domain 18 168 9.6E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03405 5cffcf97c21b353580afeb8951c7c7ea 443 Gene3D G3DSA:3.40.50.1390 16 153 3.2E-35 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03405 5cffcf97c21b353580afeb8951c7c7ea 443 SMART SM00857 17 170 4.6E-62 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03405 5cffcf97c21b353580afeb8951c7c7ea 443 SUPERFAMILY SSF53041 16 170 1.07E-39 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03405 5cffcf97c21b353580afeb8951c7c7ea 443 Pfam PF07508 Recombinase 191 276 4.4E-12 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK95_RS17470 dbbf6204908ab4a182806e069868ae3d 244 SUPERFAMILY SSF52540 7 239 4.72E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17470 dbbf6204908ab4a182806e069868ae3d 244 SMART SM00382 31 216 4.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17470 dbbf6204908ab4a182806e069868ae3d 244 Pfam PF00005 ABC transporter 23 167 3.2E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17470 dbbf6204908ab4a182806e069868ae3d 244 Gene3D G3DSA:3.40.50.300 4 239 1.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17470 dbbf6204908ab4a182806e069868ae3d 244 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 239 1.9E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS17735 dd2339a1e96a00c725f09e214e197341 110 Pfam PF02390 Putative methyltransferase 34 70 1.4E-5 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK95_RS17735 dd2339a1e96a00c725f09e214e197341 110 SUPERFAMILY SSF53335 4 73 1.38E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17735 dd2339a1e96a00c725f09e214e197341 110 Gene3D G3DSA:3.40.50.150 20 64 6.0E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01125 8e8b3df142dab84c28c849b7b55447fd 63 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 63 1.4E-10 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS01125 8e8b3df142dab84c28c849b7b55447fd 63 Gene3D G3DSA:3.40.50.970 4 63 1.8E-12 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS01125 8e8b3df142dab84c28c849b7b55447fd 63 SUPERFAMILY SSF52518 6 63 1.71E-10 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 ProSitePatterns PS00211 ABC transporters family signature. 724 738 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Pfam PF00005 ABC transporter 352 500 6.2E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Pfam PF00005 ABC transporter 607 751 2.0E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 SMART SM00382 616 800 4.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 SMART SM00382 360 549 5.8E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 550 571 4.7E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 SUPERFAMILY SSF52540 335 570 1.18E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 294 1.5E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 SUPERFAMILY SSF52540 591 820 7.48E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Gene3D G3DSA:3.40.50.300 589 820 1.7E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27640 626f0440b029312264f226d8eeb029f9 828 Gene3D G3DSA:3.40.50.300 334 566 6.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23595 7a5e9f11bcdd3bd658b05146b4484c1c 114 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 11 109 3.6E-41 T 06-07-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 CAK95_RS23595 7a5e9f11bcdd3bd658b05146b4484c1c 114 SMART SM00992 10 109 1.2E-56 T 06-07-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 CAK95_RS23595 7a5e9f11bcdd3bd658b05146b4484c1c 114 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 11 100 6.1E-27 T 06-07-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 CAK95_RS23595 7a5e9f11bcdd3bd658b05146b4484c1c 114 SUPERFAMILY SSF141255 11 101 2.09E-34 T 06-07-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 CAK95_RS02405 3e784c1e75734acefedb46e8f834763c 158 Gene3D G3DSA:2.60.40.420 34 158 1.4E-34 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02405 3e784c1e75734acefedb46e8f834763c 158 ProSitePatterns PS00079 Multicopper oxidases signature 1. 135 155 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site CAK95_RS02405 3e784c1e75734acefedb46e8f834763c 158 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 58 155 3.0E-6 T 06-07-2017 CAK95_RS02405 3e784c1e75734acefedb46e8f834763c 158 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 52 158 2.2E-9 T 06-07-2017 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CAK95_RS02405 3e784c1e75734acefedb46e8f834763c 158 SUPERFAMILY SSF49503 50 158 5.75E-30 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS25155 f3b982724ccae904b04ed85803bdb085 591 Gene3D G3DSA:3.40.50.1820 173 268 4.1E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25155 f3b982724ccae904b04ed85803bdb085 591 Pfam PF07519 Tannase and feruloyl esterase 112 589 6.2E-125 T 06-07-2017 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 CAK95_RS25155 f3b982724ccae904b04ed85803bdb085 591 SUPERFAMILY SSF53474 200 313 2.03E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12465 4ad402cd4fb9a52ab74eda3e65a4813e 256 Gene3D G3DSA:1.20.910.10 2 239 3.3E-60 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS12465 4ad402cd4fb9a52ab74eda3e65a4813e 256 Pfam PF14518 Iron-containing redox enzyme 44 213 1.6E-32 T 06-07-2017 IPR028201 PqqC-like protein CAK95_RS12465 4ad402cd4fb9a52ab74eda3e65a4813e 256 SMART SM01236 78 181 1.4E-22 T 06-07-2017 CAK95_RS12465 4ad402cd4fb9a52ab74eda3e65a4813e 256 SUPERFAMILY SSF48613 12 226 1.64E-47 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS23855 94a1aae647196736f3d0c44e3bcda023 230 Pfam PF00494 Squalene/phytoene synthase 12 156 5.3E-20 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAK95_RS23855 94a1aae647196736f3d0c44e3bcda023 230 SUPERFAMILY SSF48576 4 225 2.59E-29 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS12930 d646cb1f3ccccc1a99ab0fb553a49074 190 Gene3D G3DSA:3.40.630.30 3 127 1.2E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS12930 d646cb1f3ccccc1a99ab0fb553a49074 190 SUPERFAMILY SSF55729 2 131 9.26E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS12930 d646cb1f3ccccc1a99ab0fb553a49074 190 Pfam PF13508 Acetyltransferase (GNAT) domain 47 124 1.6E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS21740 074a59f7bb046eb77845a893df22777d 249 Gene3D G3DSA:2.40.400.10 15 246 4.3E-90 T 06-07-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CAK95_RS21740 074a59f7bb046eb77845a893df22777d 249 SUPERFAMILY SSF160104 3 247 2.49E-83 T 06-07-2017 CAK95_RS21740 074a59f7bb046eb77845a893df22777d 249 Pfam PF06314 Acetoacetate decarboxylase (ADC) 12 246 3.0E-71 T 06-07-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 Gene3D G3DSA:3.40.190.10 175 259 1.4E-19 T 06-07-2017 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 Gene3D G3DSA:3.40.190.10 90 174 1.6E-16 T 06-07-2017 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 Gene3D G3DSA:1.10.10.10 2 84 9.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 SUPERFAMILY SSF46785 2 109 3.13E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 SUPERFAMILY SSF53850 89 297 1.23E-34 T 06-07-2017 CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 Pfam PF03466 LysR substrate binding domain 88 294 9.5E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS26055 85f35bf3764a48e020c1a08d4e11e0de 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04780 db513674c57702dc82e9fe60d58c3b92 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 270 7.0E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04780 db513674c57702dc82e9fe60d58c3b92 284 Gene3D G3DSA:1.10.3720.10 82 277 2.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04780 db513674c57702dc82e9fe60d58c3b92 284 SUPERFAMILY SSF161098 84 267 9.94E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 SMART SM00363 18 83 7.6E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 324 2.0E-87 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 Gene3D G3DSA:3.10.290.10 19 67 2.8E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 SUPERFAMILY SSF55120 79 326 7.61E-69 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 Pfam PF01479 S4 domain 19 63 2.5E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 Pfam PF00849 RNA pseudouridylate synthase 92 257 5.6E-30 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS28085 062eddea06951b396a912ac70e4751be 331 SUPERFAMILY SSF55174 19 72 1.65E-8 T 06-07-2017 CAK95_RS04895 4155dd75f48650a27c1b0ffafcf944a2 260 SUPERFAMILY SSF52540 8 238 6.75E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04895 4155dd75f48650a27c1b0ffafcf944a2 260 Pfam PF00005 ABC transporter 29 166 1.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04895 4155dd75f48650a27c1b0ffafcf944a2 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS04895 4155dd75f48650a27c1b0ffafcf944a2 260 Gene3D G3DSA:3.40.50.300 8 221 1.4E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04895 4155dd75f48650a27c1b0ffafcf944a2 260 SMART SM00382 36 226 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11415 b64bd11e7575c96b43e87fcef40ab545 252 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11415 b64bd11e7575c96b43e87fcef40ab545 252 Gene3D G3DSA:3.40.50.300 4 220 7.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11415 b64bd11e7575c96b43e87fcef40ab545 252 SUPERFAMILY SSF52540 4 218 1.01E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11415 b64bd11e7575c96b43e87fcef40ab545 252 SMART SM00382 34 225 4.8E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11415 b64bd11e7575c96b43e87fcef40ab545 252 Pfam PF00005 ABC transporter 26 165 4.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 Gene3D G3DSA:1.10.10.60 242 284 8.0E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 Pfam PF12833 Helix-turn-helix domain 210 285 3.6E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 SMART SM00342 204 287 8.2E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 SUPERFAMILY SSF46689 240 286 1.33E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 Gene3D G3DSA:1.10.10.60 187 241 6.6E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 Pfam PF06719 AraC-type transcriptional regulator N-terminus 24 175 2.2E-52 T 06-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal CAK95_RS16280 c0b39845559793dc99bdbd7630208ea9 302 SUPERFAMILY SSF46689 188 238 1.39E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14925 42ac749449e0cb9687c4fcd51292f020 223 SUPERFAMILY SSF161098 18 204 1.83E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14925 42ac749449e0cb9687c4fcd51292f020 223 Gene3D G3DSA:1.10.3720.10 18 212 8.8E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14925 42ac749449e0cb9687c4fcd51292f020 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 212 4.2E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 698 716 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR00313 NodO calcium binding signature 584 595 4.7E-12 T 06-07-2017 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR00313 NodO calcium binding signature 720 728 4.7E-12 T 06-07-2017 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR00313 NodO calcium binding signature 729 738 4.7E-12 T 06-07-2017 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR00313 NodO calcium binding signature 605 613 4.7E-12 T 06-07-2017 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 707 725 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 439 457 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Gene3D G3DSA:2.150.10.10 666 774 1.5E-21 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Gene3D G3DSA:2.150.10.10 559 651 1.3E-21 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Gene3D G3DSA:2.150.10.10 418 558 9.7E-18 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 448 466 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 605 626 1.3E-6 T 06-07-2017 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 194 215 1.3E-6 T 06-07-2017 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 684 700 0.27 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 434 450 0.078 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 604 621 0.0062 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 587 603 0.013 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 568 585 0.49 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 702 718 0.0016 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 720 735 0.019 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 420 432 7.4 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 451 467 0.025 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 623 639 0.17 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 592 610 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 716 734 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 SUPERFAMILY SSF51126 129 437 3.38E-8 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 SUPERFAMILY SSF51126 15 72 3.38E-8 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 421 439 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 SUPERFAMILY SSF51120 518 657 1.31E-20 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 601 619 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 478 557 3.5E-6 T 06-07-2017 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 610 628 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 SUPERFAMILY SSF51120 631 825 6.02E-28 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS23965 7dc071402d4b9798f094bdbd6e70798e 828 SUPERFAMILY SSF51120 406 499 8.63E-17 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS19230 bf6371c67237a0c1116722c6c87db507 329 Pfam PF02424 ApbE family 31 306 9.7E-75 T 06-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 CAK95_RS19230 bf6371c67237a0c1116722c6c87db507 329 SUPERFAMILY SSF143631 23 327 1.31E-90 T 06-07-2017 IPR003374 ApbE-like domain CAK95_RS19230 bf6371c67237a0c1116722c6c87db507 329 PIRSF PIRSF006268 13 329 1.3E-80 T 06-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 Gene3D G3DSA:1.10.357.10 5 202 2.1E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 9.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 9.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 SUPERFAMILY SSF48498 95 199 9.39E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 SUPERFAMILY SSF46689 15 86 5.64E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS21110 ae35174a643b5a4c21f5648716c1b435 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.6E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS02080 35cb118cfd2396b4eb901155cc8190d9 135 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 51 134 1.6E-18 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS02080 35cb118cfd2396b4eb901155cc8190d9 135 SUPERFAMILY SSF56529 50 134 2.22E-26 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS02080 35cb118cfd2396b4eb901155cc8190d9 135 Gene3D G3DSA:3.90.850.10 50 134 1.5E-29 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00390 c64885ecb70bb62a380f8c917b19cdcd 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 4.2E-47 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 140 149 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 595 24.208 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Gene3D G3DSA:3.30.1360.70 15 119 5.1E-29 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Gene3D G3DSA:3.40.50.620 123 465 7.4E-96 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 SUPERFAMILY SSF55190 27 121 4.97E-24 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 SMART SM00836 460 595 1.0E-51 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Pfam PF00750 tRNA synthetases class I (R) 253 451 1.4E-7 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Pfam PF00750 tRNA synthetases class I (R) 122 186 3.2E-12 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 145 161 4.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 169 182 4.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 329 350 4.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 130 145 4.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 27 101 1.1E-22 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 SUPERFAMILY SSF47323 454 595 3.66E-30 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 38 595 1.7E-108 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 SUPERFAMILY SSF52374 123 471 1.58E-84 T 06-07-2017 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Gene3D G3DSA:1.10.730.10 466 595 1.5E-33 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 Pfam PF05746 DALR anticodon binding domain 460 595 1.7E-30 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAK95_RS23945 2b94da64051c718d9f026fe8388d5d82 596 SMART SM01016 9 101 4.8E-35 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK95_RS22945 0beb81759473ad6d42bb585e08e011b9 355 SUPERFAMILY SSF51395 3 352 5.07E-115 T 06-07-2017 CAK95_RS22945 0beb81759473ad6d42bb585e08e011b9 355 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 328 6.8E-79 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK95_RS22945 0beb81759473ad6d42bb585e08e011b9 355 Gene3D G3DSA:3.20.20.70 3 352 6.7E-122 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 270 444 1.1E-30 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 Pfam PF13433 Periplasmic binding protein domain 461 828 1.5E-129 T 06-07-2017 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 SMART SM00283 195 446 9.1E-25 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 SUPERFAMILY SSF53822 461 834 1.65E-76 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 SUPERFAMILY SSF58104 208 450 1.83E-46 T 06-07-2017 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 Gene3D G3DSA:3.40.50.2300 576 766 3.0E-54 T 06-07-2017 CAK95_RS08110 f8425e3a3993c9a20c3bf14d88b0a4cd 839 Gene3D G3DSA:1.10.287.950 218 443 6.1E-40 T 06-07-2017 CAK95_RS07780 5785cb8580bb559e18ba0fae3267f9c5 367 Gene3D G3DSA:1.10.620.20 37 326 1.4E-87 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK95_RS07780 5785cb8580bb559e18ba0fae3267f9c5 367 PIRSF PIRSF000355 24 355 1.5E-90 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07780 5785cb8580bb559e18ba0fae3267f9c5 367 SUPERFAMILY SSF47240 41 345 1.54E-75 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS07780 5785cb8580bb559e18ba0fae3267f9c5 367 Pfam PF00268 Ribonucleotide reductase, small chain 42 303 3.4E-63 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS27345 ef855d62084c835926ba11e030b51d13 332 Gene3D G3DSA:3.40.190.10 121 245 9.6E-17 T 06-07-2017 CAK95_RS27345 ef855d62084c835926ba11e030b51d13 332 Pfam PF09084 NMT1/THI5 like 48 259 1.0E-35 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS27345 ef855d62084c835926ba11e030b51d13 332 SUPERFAMILY SSF53850 47 285 8.26E-36 T 06-07-2017 CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 0.003 T 06-07-2017 CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 Pfam PF00106 short chain dehydrogenase 8 193 5.3E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 SUPERFAMILY SSF51735 6 251 5.89E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS09910 a55520b567b908c9e42a6cefeff85c45 253 Gene3D G3DSA:3.40.50.720 6 251 3.9E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15120 27bfe7eee50e9c3192990728c8709863 188 PIRSF PIRSF033924 2 188 6.1E-90 T 06-07-2017 IPR008325 Uncharacterised conserved protein UCP033924 CAK95_RS15120 27bfe7eee50e9c3192990728c8709863 188 Pfam PF06577 Protein of unknown function (DUF1134) 30 188 9.7E-77 T 06-07-2017 IPR008325 Uncharacterised conserved protein UCP033924 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Gene3D G3DSA:3.40.50.10490 244 440 2.3E-58 T 06-07-2017 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 1.3E-240 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Gene3D G3DSA:3.40.50.10490 441 608 3.1E-64 T 06-07-2017 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 39.436 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 SUPERFAMILY SSF53697 244 608 4.62E-108 T 06-07-2017 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Pfam PF13522 Glutamine amidotransferase domain 67 191 1.2E-22 T 06-07-2017 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Gene3D G3DSA:3.60.20.10 2 236 7.3E-77 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Pfam PF01380 SIS domain 291 415 4.7E-28 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 Pfam PF01380 SIS domain 462 590 4.3E-27 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS23650 15d1f19423f78680a380887dfad875c9 608 SUPERFAMILY SSF56235 2 233 1.63E-76 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 Gene3D G3DSA:3.30.450.40 73 243 6.7E-24 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 SUPERFAMILY SSF55781 79 250 2.03E-23 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 Gene3D G3DSA:1.10.10.10 2 70 2.0E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 SMART SM00346 3 90 3.8E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 Pfam PF09339 IclR helix-turn-helix domain 5 54 1.6E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 SUPERFAMILY SSF46785 3 70 2.05E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00125 5443fbc1d9eae1eaa320db5dbd558ef8 279 Pfam PF01614 Bacterial transcriptional regulator 127 248 1.2E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 Gene3D G3DSA:3.30.70.360 187 303 5.1E-44 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 Pfam PF01546 Peptidase family M20/M25/M40 79 386 5.6E-38 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 Pfam PF07687 Peptidase dimerisation domain 192 286 9.3E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 SUPERFAMILY SSF55031 190 302 6.28E-33 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 PIRSF PIRSF005962 3 390 8.8E-126 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 377 7.2E-113 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 SUPERFAMILY SSF53187 304 389 2.61E-85 T 06-07-2017 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 SUPERFAMILY SSF53187 2 203 2.61E-85 T 06-07-2017 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 Gene3D G3DSA:3.40.630.10 3 184 9.7E-99 T 06-07-2017 CAK95_RS23685 fe610cc08b1bc4af366e6e0acdcdc152 391 Gene3D G3DSA:3.40.630.10 304 389 9.7E-99 T 06-07-2017 CAK95_RS08590 d94f1adff5e525bf94fa3ff1bda998fd 408 Gene3D G3DSA:3.90.1150.10 273 407 2.0E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS08590 d94f1adff5e525bf94fa3ff1bda998fd 408 Pfam PF00155 Aminotransferase class I and II 42 403 1.9E-44 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS08590 d94f1adff5e525bf94fa3ff1bda998fd 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 252 265 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAK95_RS08590 d94f1adff5e525bf94fa3ff1bda998fd 408 SUPERFAMILY SSF53383 32 407 1.15E-80 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS08590 d94f1adff5e525bf94fa3ff1bda998fd 408 Gene3D G3DSA:3.40.640.10 57 272 2.8E-54 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:3.30.2090.10 184 277 3.1E-25 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:3.30.2090.10 732 816 2.9E-23 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82714 732 817 5.62E-21 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:3.30.70.1430 579 681 9.9E-29 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 575 681 3.14E-26 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.8E-94 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82866 301 499 2.88E-53 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Pfam PF00873 AcrB/AcrD/AcrF family 4 1036 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1040 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 40 134 9.94E-28 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:3.30.70.1430 40 141 3.5E-34 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 682 731 1.78E-26 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 818 867 1.78E-26 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82866 841 1036 1.57E-43 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 138 184 2.2E-26 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82693 277 333 2.2E-26 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:1.10.3850.10 825 1037 1.6E-54 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 Gene3D G3DSA:1.10.3850.10 285 500 1.8E-62 T 06-07-2017 CAK95_RS27665 47fcb991184ec0661fa9e99925626a61 1072 SUPERFAMILY SSF82714 185 274 1.96E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS16350 24667acb3b9d1009f2532cd532337720 321 PIRSF PIRSF017082 2 321 4.3E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16350 24667acb3b9d1009f2532cd532337720 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 317 2.1E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16350 24667acb3b9d1009f2532cd532337720 321 SUPERFAMILY SSF53850 108 285 1.45E-14 T 06-07-2017 CAK95_RS21415 e343fcad14d2c93ec07707036c86db9e 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 142 2.2E-16 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 SUPERFAMILY SSF88659 192 285 1.12E-20 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 SUPERFAMILY SSF88946 13 121 1.31E-38 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PRINTS PR00046 Major sigma-70 factor signature 77 90 1.3E-21 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PRINTS PR00046 Major sigma-70 factor signature 268 279 1.3E-21 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PRINTS PR00046 Major sigma-70 factor signature 101 109 1.3E-21 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PRINTS PR00046 Major sigma-70 factor signature 234 246 1.3E-21 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PRINTS PR00046 Major sigma-70 factor signature 253 268 1.3E-21 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 282 3.8E-32 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Pfam PF04542 Sigma-70 region 2 53 121 1.0E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 285 52.255 T 06-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Pfam PF00140 Sigma-70 factor, region 1.2 17 44 8.3E-6 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 253 279 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 284 6.5E-116 T 06-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 PIRSF PIRSF000770 4 301 5.1E-37 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Pfam PF04545 Sigma-70, region 4 230 281 1.5E-17 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Gene3D G3DSA:1.10.601.10 16 119 2.6E-36 T 06-07-2017 CAK95_RS28090 129476f7ed36eb255745c2d62a3066be 302 Gene3D G3DSA:1.10.10.10 225 286 2.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 Pfam PF00460 Flagella basal body rod protein 7 36 9.3E-7 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 SUPERFAMILY SSF64518 129 366 5.36E-13 T 06-07-2017 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 SUPERFAMILY SSF64518 425 618 5.36E-13 T 06-07-2017 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 3.7E-9 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 3.7E-9 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 3.7E-9 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 558 618 8.8E-8 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAK95_RS18125 2eb8b7972c4ad73f6afa418d8ead9e04 619 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 363 8.2E-72 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAK95_RS07375 11db3e79cce4a7a2a16ec1adb30ddc51 134 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 3 133 1.8E-44 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CAK95_RS07375 11db3e79cce4a7a2a16ec1adb30ddc51 134 Gene3D G3DSA:2.20.25.10 3 40 4.3E-9 T 06-07-2017 CAK95_RS07375 11db3e79cce4a7a2a16ec1adb30ddc51 134 Gene3D G3DSA:3.30.300.20 42 134 5.4E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS07375 11db3e79cce4a7a2a16ec1adb30ddc51 134 SUPERFAMILY SSF82784 2 133 1.28E-38 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS07375 11db3e79cce4a7a2a16ec1adb30ddc51 134 Pfam PF02566 OsmC-like protein 36 131 8.4E-20 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Gene3D G3DSA:2.40.40.20 588 711 9.1E-40 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Gene3D G3DSA:3.40.228.10 142 328 1.2E-54 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 13 31 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Pfam PF01568 Molydopterin dinucleotide binding domain 594 705 3.2E-28 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Gene3D G3DSA:3.40.50.740 329 577 3.4E-87 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Gene3D G3DSA:3.40.50.740 65 141 3.4E-87 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Gene3D G3DSA:2.20.25.90 10 59 1.9E-17 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Pfam PF00384 Molybdopterin oxidoreductase 65 493 3.1E-76 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 SUPERFAMILY SSF53706 9 578 9.16E-183 T 06-07-2017 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 SMART SM00926 8 62 9.1E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 59 5.6E-18 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 Pfam PF04324 BFD-like [2Fe-2S] binding domain 840 889 1.1E-13 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAK95_RS17035 29595fd8220aff418877577e91d62d44 900 SUPERFAMILY SSF50692 566 710 4.07E-42 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS08740 849d0da10e079ac4777d338e316ae77a 100 Gene3D G3DSA:3.30.70.900 1 99 1.0E-25 T 06-07-2017 CAK95_RS08740 849d0da10e079ac4777d338e316ae77a 100 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 93 3.0E-21 T 06-07-2017 IPR009799 EthD domain CAK95_RS08740 849d0da10e079ac4777d338e316ae77a 100 SUPERFAMILY SSF54909 1 97 2.41E-22 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS08740 849d0da10e079ac4777d338e316ae77a 100 Pfam PF07110 EthD domain 13 86 2.7E-8 T 06-07-2017 IPR009799 EthD domain CAK95_RS02060 b47a07dafdce1adc675ee852b0c144fd 354 Pfam PF00296 Luciferase-like monooxygenase 15 312 1.8E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02060 b47a07dafdce1adc675ee852b0c144fd 354 Gene3D G3DSA:3.20.20.30 15 348 7.8E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02060 b47a07dafdce1adc675ee852b0c144fd 354 SUPERFAMILY SSF51679 14 348 1.3E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 498 6.8E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Gene3D G3DSA:3.40.50.980 168 318 2.5E-42 T 06-07-2017 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Pfam PF00501 AMP-binding enzyme 9 414 3.0E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Gene3D G3DSA:2.30.38.10 333 405 4.6E-23 T 06-07-2017 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Gene3D G3DSA:3.40.50.980 3 167 1.9E-41 T 06-07-2017 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 PRINTS PR00154 AMP-binding signature 169 177 5.7E-6 T 06-07-2017 IPR020459 AMP-binding CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 PRINTS PR00154 AMP-binding signature 157 168 5.7E-6 T 06-07-2017 IPR020459 AMP-binding CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 Gene3D G3DSA:3.30.300.30 409 509 3.9E-35 T 06-07-2017 CAK95_RS07180 6a641e7802a0a249f4c786cf5b202fa6 517 SUPERFAMILY SSF56801 3 510 7.46E-158 T 06-07-2017 CAK95_RS16865 abca72034ba597a98133fbd078fa9910 217 Pfam PF06267 Family of unknown function (DUF1028) 2 190 5.3E-61 T 06-07-2017 IPR010430 Protein of unknown function DUF1028 CAK95_RS16865 abca72034ba597a98133fbd078fa9910 217 SUPERFAMILY SSF56235 1 215 2.55E-67 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS16865 abca72034ba597a98133fbd078fa9910 217 Gene3D G3DSA:3.60.20.10 1 209 2.4E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 98 114 8.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 84 98 8.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 SUPERFAMILY SSF46785 56 128 3.06E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 Gene3D G3DSA:1.20.120.530 145 279 1.1E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 Gene3D G3DSA:1.10.10.10 56 126 8.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 SMART SM00345 60 124 6.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 SUPERFAMILY SSF48008 144 278 2.17E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 SMART SM00895 146 271 4.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 Pfam PF00392 Bacterial regulatory proteins, gntR family 57 123 3.2E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27230 2cd4fe444e994ac1f0a97d6baaef537c 287 Pfam PF07729 FCD domain 146 270 1.0E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Pfam PF00732 GMC oxidoreductase 232 332 6.9E-11 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 SUPERFAMILY SSF54373 438 492 5.49E-6 T 06-07-2017 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 SUPERFAMILY SSF51905 8 341 1.8E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 SUPERFAMILY SSF51905 518 578 1.8E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Pfam PF05199 GMC oxidoreductase 447 570 9.4E-21 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Gene3D G3DSA:3.50.50.60 453 466 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Gene3D G3DSA:3.50.50.60 509 575 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Gene3D G3DSA:3.50.50.60 243 349 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14770 29a445759bcc67c3bf166c4d618de815 588 Gene3D G3DSA:3.50.50.60 9 158 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08860 71d8820ca7ce97ac3f4ce3316933b0a1 404 SUPERFAMILY SSF53822 64 390 6.48E-60 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS08860 71d8820ca7ce97ac3f4ce3316933b0a1 404 Gene3D G3DSA:3.40.50.2300 180 324 9.4E-16 T 06-07-2017 CAK95_RS08860 71d8820ca7ce97ac3f4ce3316933b0a1 404 Pfam PF13458 Periplasmic binding protein 65 387 6.4E-34 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS08860 71d8820ca7ce97ac3f4ce3316933b0a1 404 Gene3D G3DSA:3.40.50.2300 62 179 5.7E-19 T 06-07-2017 CAK95_RS08860 71d8820ca7ce97ac3f4ce3316933b0a1 404 Gene3D G3DSA:3.40.50.2300 325 373 5.7E-19 T 06-07-2017 CAK95_RS14750 6c8ca130d23bbff8a098a6de82a8e151 251 Gene3D G3DSA:3.40.50.300 7 198 3.0E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14750 6c8ca130d23bbff8a098a6de82a8e151 251 SMART SM00382 19 199 9.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14750 6c8ca130d23bbff8a098a6de82a8e151 251 SUPERFAMILY SSF52540 9 219 7.14E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14750 6c8ca130d23bbff8a098a6de82a8e151 251 Pfam PF00005 ABC transporter 11 149 1.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14750 6c8ca130d23bbff8a098a6de82a8e151 251 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 Pfam PF03481 Putative GTP-binding controlling metal-binding 202 324 1.0E-21 T 06-07-2017 IPR005145 Putative GTP-binding controlling metal-binding domain CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 Gene3D G3DSA:3.90.870.10 12 206 1.4E-73 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 18 209 1.2E-55 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 PIRSF PIRSF004930 1 329 3.4E-110 T 06-07-2017 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 SUPERFAMILY SSF55821 14 210 1.5E-60 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK95_RS15750 9c0ddd25785eadeaa2b7bcaf52107e30 333 Pfam PF01300 Telomere recombination 23 198 8.8E-55 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAK95_RS10300 0e3026788d4a42f8cf690e76eda95e2a 561 Gene3D G3DSA:2.40.50.100 60 92 5.6E-12 T 06-07-2017 CAK95_RS10300 0e3026788d4a42f8cf690e76eda95e2a 561 Gene3D G3DSA:2.40.50.100 237 265 5.6E-12 T 06-07-2017 CAK95_RS10300 0e3026788d4a42f8cf690e76eda95e2a 561 SUPERFAMILY SSF111369 47 137 5.89E-7 T 06-07-2017 CAK95_RS10300 0e3026788d4a42f8cf690e76eda95e2a 561 SUPERFAMILY SSF111369 190 354 4.71E-11 T 06-07-2017 CAK95_RS10300 0e3026788d4a42f8cf690e76eda95e2a 561 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 47 349 1.2E-14 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 Pfam PF00106 short chain dehydrogenase 7 194 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PIRSF PIRSF000126 1 262 1.2E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 Gene3D G3DSA:3.40.50.720 5 200 4.7E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08355 9074feed47a1a39547830841e2b62c0d 262 SUPERFAMILY SSF51735 3 248 1.67E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 Gene3D G3DSA:3.40.1690.10 219 352 2.6E-56 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 9 352 1.4E-112 T 06-07-2017 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 1.4E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 1.4E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 1.4E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 1.4E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 1.4E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 SUPERFAMILY SSF160544 253 353 5.49E-39 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAK95_RS18300 f2c37e3c0d911b28291a8fdba26b6385 355 Pfam PF01312 FlhB HrpN YscU SpaS Family 9 347 1.2E-118 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 SUPERFAMILY SSF46785 240 311 5.44E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 Gene3D G3DSA:3.90.79.10 14 124 1.3E-11 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 Gene3D G3DSA:3.90.79.10 214 246 1.3E-11 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 PIRSF PIRSF019423 2 321 8.8E-135 T 06-07-2017 IPR011213 Nicotinic acid mononucleotide biosynthesis protein CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 Gene3D G3DSA:1.10.10.10 247 312 3.5E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15665 60f93d70d4ef1d01e7347b6df2fc70bf 321 SUPERFAMILY SSF55811 14 145 7.7E-10 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 136 1.1E-38 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 SUPERFAMILY SSF51735 136 317 2.79E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 SMART SM01002 145 311 2.1E-88 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 169 194 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 Gene3D G3DSA:3.40.50.1770 187 367 2.0E-42 T 06-07-2017 CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 SMART SM01003 4 136 1.7E-55 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 Gene3D G3DSA:3.40.50.1770 2 186 8.9E-56 T 06-07-2017 CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 368 1.9E-73 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK95_RS28405 6c0679de1ad22ec745e53b041b809d9d 377 SUPERFAMILY SSF52283 1 167 1.96E-47 T 06-07-2017 CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 SMART SM00829 10 348 1.8E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 SUPERFAMILY SSF51735 148 313 1.23E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 4.7E-30 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 Gene3D G3DSA:3.40.50.720 185 299 1.4E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 Pfam PF00107 Zinc-binding dehydrogenase 186 312 1.7E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 SUPERFAMILY SSF50129 1 180 2.67E-43 T 06-07-2017 IPR011032 GroES-like CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK95_RS06265 f8dcc2a85b5006c78223a4c33db174cd 351 Gene3D G3DSA:3.90.180.10 1 184 3.9E-46 T 06-07-2017 IPR011032 GroES-like CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Gene3D G3DSA:3.40.50.970 29 207 2.6E-21 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 228 359 2.2E-17 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 SUPERFAMILY SSF52518 411 583 6.63E-29 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 SUPERFAMILY SSF52518 30 213 1.93E-18 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 430 579 6.2E-23 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Gene3D G3DSA:3.40.50.970 422 582 1.8E-26 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Gene3D G3DSA:3.40.50.1220 222 421 1.0E-26 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 30 203 1.8E-16 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS10095 89def9459097bedc3521514cd3af74cb 615 SUPERFAMILY SSF52467 189 387 9.16E-25 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 Pfam PF04542 Sigma-70 region 2 21 79 3.8E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 171 8.1E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 SUPERFAMILY SSF88659 110 171 6.54E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 Gene3D G3DSA:1.10.10.10 110 170 2.5E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 Pfam PF08281 Sigma-70, region 4 118 169 6.7E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 SUPERFAMILY SSF88946 7 88 5.49E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 35 66 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09265 62edf8d75048b62472b9b1bfe756ad2d 419 Gene3D G3DSA:1.10.1740.10 5 81 1.6E-12 T 06-07-2017 CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 Gene3D G3DSA:3.40.710.10 222 550 2.6E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 Pfam PF03717 Penicillin-binding Protein dimerisation domain 75 183 2.7E-10 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 SUPERFAMILY SSF56519 73 198 8.63E-31 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 Gene3D G3DSA:3.90.1310.10 143 198 7.5E-13 T 06-07-2017 CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 SUPERFAMILY SSF56601 223 559 3.64E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS13585 b00d5a9d16a2cb0b1d4b3d87743ed520 577 Pfam PF00905 Penicillin binding protein transpeptidase domain 249 528 2.8E-57 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SUPERFAMILY SSF55073 666 822 9.42E-40 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SMART SM00052 831 1072 5.0E-114 T 06-07-2017 IPR001633 EAL domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.30.450.20 242 350 1.9E-4 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Pfam PF00563 EAL domain 840 1067 4.6E-71 T 06-07-2017 IPR001633 EAL domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SMART SM00091 409 477 5.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SMART SM00091 535 602 1.3E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SUPERFAMILY SSF55785 520 648 6.11E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SUPERFAMILY SSF55785 402 521 1.68E-9 T 06-07-2017 IPR000014 PAS domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SMART SM00267 650 821 3.8E-58 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Pfam PF08448 PAS fold 541 652 1.1E-14 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 657 819 7.9E-36 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.30.450.20 402 521 1.4E-13 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.30.450.20 522 642 1.7E-20 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.30.450.20 162 241 1.2E-10 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Pfam PF12860 PAS fold 415 527 6.5E-31 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.30.70.270 662 827 1.0E-50 T 06-07-2017 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Gene3D G3DSA:3.20.20.450 835 1077 1.2E-94 T 06-07-2017 IPR001633 EAL domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 536 656 2.9E-11 T 06-07-2017 IPR000014 PAS domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 SUPERFAMILY SSF141868 838 1077 5.62E-89 T 06-07-2017 IPR001633 EAL domain CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Pfam PF02743 Cache domain 102 337 2.2E-19 T 06-07-2017 IPR033479 Double Cache domain 1 CAK95_RS18595 83eef1d906e159ead1f9bdd6e54c2374 1091 Pfam PF00990 Diguanylate cyclase, GGDEF domain 661 816 3.0E-39 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Gene3D G3DSA:3.40.50.720 402 470 5.4E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Gene3D G3DSA:3.40.50.720 147 233 5.4E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 453 1.6E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 6.5E-22 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 6.5E-22 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 6.5E-22 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 6.5E-22 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 471 4.9E-207 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Gene3D G3DSA:1.10.1060.10 3 146 1.3E-44 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 131 1.4E-27 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 SUPERFAMILY SSF51971 142 397 2.71E-68 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 Gene3D G3DSA:3.50.50.60 234 397 9.7E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 SUPERFAMILY SSF51971 358 469 1.29E-11 T 06-07-2017 CAK95_RS16435 880e4f667366e4a28b6feb09f3f180c1 472 SUPERFAMILY SSF46548 2 154 9.68E-42 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SMART SM00091 17 85 0.001 T 06-07-2017 IPR000014 PAS domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Gene3D G3DSA:3.30.450.20 20 122 6.1E-15 T 06-07-2017 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 368 9.7E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SUPERFAMILY SSF55874 194 370 1.19E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SUPERFAMILY SSF47384 139 202 1.71E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SMART SM00388 143 207 5.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Pfam PF00989 PAS fold 20 123 4.9E-7 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SMART SM00387 248 370 2.8E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Gene3D G3DSA:1.10.287.130 141 197 5.9E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Gene3D G3DSA:3.30.565.10 207 368 4.6E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 Pfam PF00512 His Kinase A (phospho-acceptor) domain 145 201 2.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 SUPERFAMILY SSF55785 9 117 4.82E-6 T 06-07-2017 IPR000014 PAS domain CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 330 6.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 316 6.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 349 6.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23250 e113be560aa5e3d2f77d7a6545de4ac0 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 6.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS10445 87683ed322d9ea55a5f15ce4b72fa8ba 302 Pfam PF08241 Methyltransferase domain 89 140 1.3E-10 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS10445 87683ed322d9ea55a5f15ce4b72fa8ba 302 Gene3D G3DSA:3.40.50.150 88 265 9.2E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10445 87683ed322d9ea55a5f15ce4b72fa8ba 302 SUPERFAMILY SSF53335 52 217 1.33E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 SUPERFAMILY SSF143724 136 335 5.89E-62 T 06-07-2017 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 SUPERFAMILY SSF56024 340 516 1.61E-51 T 06-07-2017 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 PIRSF PIRSF015589 15 725 4.4E-266 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Gene3D G3DSA:3.30.870.10 523 707 1.6E-71 T 06-07-2017 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Pfam PF13090 Polyphosphate kinase C-terminal domain 353 706 1.1E-148 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 SUPERFAMILY SSF56024 525 707 2.11E-68 T 06-07-2017 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Pfam PF02503 Polyphosphate kinase middle domain 148 343 3.5E-58 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 SUPERFAMILY SSF140356 31 135 4.97E-38 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Gene3D G3DSA:3.30.870.10 341 522 9.5E-71 T 06-07-2017 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 33 708 8.6E-287 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Pfam PF13089 Polyphosphate kinase N-terminal domain 34 138 1.4E-37 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Hamap MF_00347 Polyphosphate kinase [ppk]. 31 710 31.22 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK95_RS25725 4b3506da46a091d41b91cb87311b39d1 733 Gene3D G3DSA:3.30.1840.10 135 322 2.7E-60 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 SUPERFAMILY SSF52540 364 595 3.55E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27400 81e644354a824ba58580e4240437b081 613 SUPERFAMILY SSF52540 4 252 1.52E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Gene3D G3DSA:3.40.50.300 2 254 5.4E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Pfam PF00005 ABC transporter 23 180 3.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Pfam PF00005 ABC transporter 373 522 1.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 575 603 3.8E-7 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 298 8.9E-15 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 Gene3D G3DSA:3.40.50.300 341 599 6.9E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27400 81e644354a824ba58580e4240437b081 613 SMART SM00382 32 230 6.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27400 81e644354a824ba58580e4240437b081 613 SMART SM00382 381 573 4.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27400 81e644354a824ba58580e4240437b081 613 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27400 81e644354a824ba58580e4240437b081 613 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 6.7E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS06990 9a904a3293820b3e7f1cd15671a93aa8 262 Gene3D G3DSA:3.40.50.1980 127 255 5.1E-17 T 06-07-2017 CAK95_RS06990 9a904a3293820b3e7f1cd15671a93aa8 262 Pfam PF01497 Periplasmic binding protein 7 234 4.5E-36 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK95_RS06990 9a904a3293820b3e7f1cd15671a93aa8 262 Gene3D G3DSA:3.40.50.1980 3 122 2.1E-23 T 06-07-2017 CAK95_RS06990 9a904a3293820b3e7f1cd15671a93aa8 262 SUPERFAMILY SSF53807 3 256 3.41E-48 T 06-07-2017 CAK95_RS04560 cc800e3fb0e7f69bbecbf41f28cdf3fd 450 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 448 5.8E-81 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS04560 cc800e3fb0e7f69bbecbf41f28cdf3fd 450 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 442 3.5E-78 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS04560 cc800e3fb0e7f69bbecbf41f28cdf3fd 450 PIRSF PIRSF006066 6 450 3.2E-77 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 3 304 35.157 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 Gene3D G3DSA:3.40.50.170 2 206 3.8E-69 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 SUPERFAMILY SSF53328 3 208 5.63E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 4 302 6.3E-82 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 Pfam PF00551 Formyl transferase 8 182 3.9E-41 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 Gene3D G3DSA:3.10.25.10 209 309 6.5E-32 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 SUPERFAMILY SSF50486 206 309 1.73E-30 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS02840 6366e6691970f4f84f2193df2b83d246 310 Pfam PF02911 Formyl transferase, C-terminal domain 205 301 2.1E-27 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS20175 8d184fec8dd1c54bf8447aeed7078590 94 Gene3D G3DSA:1.10.1200.10 2 91 3.4E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS20175 8d184fec8dd1c54bf8447aeed7078590 94 Pfam PF00550 Phosphopantetheine attachment site 6 59 8.5E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS20175 8d184fec8dd1c54bf8447aeed7078590 94 SUPERFAMILY SSF47336 2 62 3.53E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 19 135 1.7E-30 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 20 37 - T 06-07-2017 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 PIRSF PIRSF003230 7 151 7.6E-42 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 Gene3D G3DSA:3.10.129.10 12 144 2.2E-45 T 06-07-2017 IPR029069 HotDog domain CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 15 141 9.3E-47 T 06-07-2017 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 Pfam PF03061 Thioesterase superfamily 30 119 1.7E-17 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS04035 aab0f5bd1b3548b014e9b95970673877 153 SUPERFAMILY SSF54637 13 144 1.47E-36 T 06-07-2017 IPR029069 HotDog domain CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 SUPERFAMILY SSF64005 15 239 6.8E-84 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 243 9.6E-83 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 Gene3D G3DSA:3.40.1180.10 12 245 4.2E-96 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 243 9.6E-79 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 244 40.531 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK95_RS22975 e667364561f53a9a9e2a004d861ce4d8 250 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 189 206 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAK95_RS01805 a11b14e029f53d802f8004253685e73c 435 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 423 1.2E-79 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS01805 a11b14e029f53d802f8004253685e73c 435 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 429 3.7E-104 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS01805 a11b14e029f53d802f8004253685e73c 435 PIRSF PIRSF006066 5 435 8.7E-81 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS27205 a8bc97ebe81dbfa0e48273039fd5f743 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 38 166 3.9E-18 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS12185 655220e959cc1060036ed0767d6beabb 215 Pfam PF01926 50S ribosome-binding GTPase 40 158 7.5E-19 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS12185 655220e959cc1060036ed0767d6beabb 215 Gene3D G3DSA:3.40.50.300 27 211 4.7E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12185 655220e959cc1060036ed0767d6beabb 215 SUPERFAMILY SSF52540 21 210 3.54E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12185 655220e959cc1060036ed0767d6beabb 215 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 22 206 1.7E-63 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CAK95_RS12185 655220e959cc1060036ed0767d6beabb 215 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 26 210 26.009 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CAK95_RS25625 62216daf1912bafee85f897020c104a0 289 SUPERFAMILY SSF88713 65 251 1.01E-52 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS25625 62216daf1912bafee85f897020c104a0 289 Gene3D G3DSA:3.20.20.370 64 252 1.2E-55 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS25625 62216daf1912bafee85f897020c104a0 289 Pfam PF01522 Polysaccharide deacetylase 68 182 5.8E-27 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS21515 c8a332469ea19eb28756e0f66d2e4301 257 Gene3D G3DSA:1.10.3580.10 89 253 4.2E-51 T 06-07-2017 IPR023335 Orthogonal Bundle domain in ATP12 CAK95_RS21515 c8a332469ea19eb28756e0f66d2e4301 257 SUPERFAMILY SSF160909 8 253 4.45E-79 T 06-07-2017 CAK95_RS21515 c8a332469ea19eb28756e0f66d2e4301 257 Pfam PF07542 ATP12 chaperone protein 30 147 1.4E-33 T 06-07-2017 IPR011419 ATP12, ATPase F1F0-assembly protein GO:0043461 CAK95_RS21515 c8a332469ea19eb28756e0f66d2e4301 257 Gene3D G3DSA:3.30.2180.10 15 87 1.2E-23 T 06-07-2017 CAK95_RS19550 6e2559e99a3a36301d5a256602fe7d82 676 Gene3D G3DSA:3.40.50.300 100 209 1.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19550 6e2559e99a3a36301d5a256602fe7d82 676 Gene3D G3DSA:3.40.50.300 348 551 1.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19550 6e2559e99a3a36301d5a256602fe7d82 676 SUPERFAMILY SSF52540 106 553 7.01E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19550 6e2559e99a3a36301d5a256602fe7d82 676 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 112 554 7.7E-99 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CAK95_RS01050 0d9a1510ac99eb2e80e15b54a0fd793d 411 Gene3D G3DSA:3.40.50.1820 23 408 4.7E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01050 0d9a1510ac99eb2e80e15b54a0fd793d 411 SUPERFAMILY SSF53474 17 173 2.9E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01050 0d9a1510ac99eb2e80e15b54a0fd793d 411 SUPERFAMILY SSF53474 336 408 2.9E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS10605 0c7e9dc04cdfd8e70bba333005e46a99 312 SUPERFAMILY SSF53850 102 274 2.24E-18 T 06-07-2017 CAK95_RS10605 0c7e9dc04cdfd8e70bba333005e46a99 312 Gene3D G3DSA:3.40.190.10 251 271 2.0E-10 T 06-07-2017 CAK95_RS10605 0c7e9dc04cdfd8e70bba333005e46a99 312 Gene3D G3DSA:3.40.190.10 115 217 2.0E-10 T 06-07-2017 CAK95_RS10605 0c7e9dc04cdfd8e70bba333005e46a99 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 35 309 1.1E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10605 0c7e9dc04cdfd8e70bba333005e46a99 312 PIRSF PIRSF017082 4 312 3.2E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 TIGRFAM TIGR00586 mutt: mutator mutT protein 7 130 6.4E-32 T 06-07-2017 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.3E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.3E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 Pfam PF00293 NUDIX domain 8 130 1.5E-22 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 Gene3D G3DSA:3.90.79.10 8 130 1.4E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS10455 37b9a4f08ba36ed6fcbba501466c34dd 134 SUPERFAMILY SSF55811 5 130 2.17E-40 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 SUPERFAMILY SSF81464 37 124 1.23E-18 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 Gene3D G3DSA:2.60.40.420 122 285 1.2E-38 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 PIRSF PIRSF000292 6 298 2.4E-117 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 Gene3D G3DSA:1.10.287.90 36 120 1.8E-27 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 155 223 6.6E-5 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 26 245 3.1E-94 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 SUPERFAMILY SSF49503 129 286 8.52E-47 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS00870 4ffa47999f01f2a8221f0556d2b16fdf 299 Pfam PF06481 COX Aromatic Rich Motif 245 290 1.9E-20 T 06-07-2017 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CAK95_RS22305 191dabdd10874b49ebc98e4abeec76f8 393 Pfam PF13356 Domain of unknown function (DUF4102) 27 95 8.3E-14 T 06-07-2017 IPR025166 Domain of unknown function DUF4102 CAK95_RS22305 191dabdd10874b49ebc98e4abeec76f8 393 Gene3D G3DSA:1.10.150.130 108 197 6.0E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS22305 191dabdd10874b49ebc98e4abeec76f8 393 Pfam PF00589 Phage integrase family 207 367 1.1E-25 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS22305 191dabdd10874b49ebc98e4abeec76f8 393 SUPERFAMILY SSF56349 108 374 2.62E-62 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS22305 191dabdd10874b49ebc98e4abeec76f8 393 Gene3D G3DSA:1.10.443.10 204 378 5.8E-41 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS27630 78cd41545f66159fda6064cf810ebc02 128 Pfam PF07366 SnoaL-like polyketide cyclase 8 128 9.1E-37 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS27630 78cd41545f66159fda6064cf810ebc02 128 SUPERFAMILY SSF54427 5 128 4.99E-31 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS27630 78cd41545f66159fda6064cf810ebc02 128 Gene3D G3DSA:3.10.450.50 8 128 7.2E-19 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 Pfam PF00107 Zinc-binding dehydrogenase 177 304 4.7E-38 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 Gene3D G3DSA:3.40.50.720 171 288 1.9E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 SMART SM00829 5 338 2.8E-30 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 SUPERFAMILY SSF50129 2 167 8.22E-45 T 06-07-2017 IPR011032 GroES-like CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 SUPERFAMILY SSF51735 137 292 1.4E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 Gene3D G3DSA:3.90.180.10 1 170 6.4E-42 T 06-07-2017 IPR011032 GroES-like CAK95_RS20150 dacffd87b1769f83121c60f152460561 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 1.1E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS00070 3810b3c68a497f3efabda4052a911765 264 Gene3D G3DSA:3.20.20.60 5 251 2.0E-63 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS00070 3810b3c68a497f3efabda4052a911765 264 SUPERFAMILY SSF51621 4 250 5.97E-63 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS00070 3810b3c68a497f3efabda4052a911765 264 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 19 239 2.0E-31 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 Gene3D G3DSA:3.30.450.40 192 359 4.7E-34 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 17 350 29.108 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 SUPERFAMILY SSF46785 17 100 2.51E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 PIRSF PIRSF005485 15 361 1.3E-104 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 Pfam PF01628 HrcA protein C terminal domain 120 343 7.8E-54 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 19 356 4.8E-95 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 SUPERFAMILY SSF55781 88 359 2.35E-54 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 17 73 1.2E-4 T 06-07-2017 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CAK95_RS08895 916d73eaf649cf982fe15a8e2fff0878 363 Gene3D G3DSA:1.10.10.10 13 99 5.5E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 Gene3D G3DSA:2.170.130.10 115 231 2.6E-17 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 Gene3D G3DSA:2.170.130.10 67 78 2.6E-17 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 Pfam PF07715 TonB-dependent Receptor Plug Domain 125 229 5.2E-12 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 Gene3D G3DSA:2.40.170.20 232 802 4.9E-67 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 SUPERFAMILY SSF56935 71 76 3.36E-80 T 06-07-2017 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 SUPERFAMILY SSF56935 121 802 3.36E-80 T 06-07-2017 CAK95_RS19330 8455687ce9e93ae7fc69d9da83b0a05d 802 Pfam PF00593 TonB dependent receptor 522 801 3.3E-22 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS25910 c4e374f5b594403cf2133fd57b913e91 163 SUPERFAMILY SSF54995 1 104 1.09E-31 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25910 c4e374f5b594403cf2133fd57b913e91 163 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 19.556 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS25910 c4e374f5b594403cf2133fd57b913e91 163 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 94 5.7E-23 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25910 c4e374f5b594403cf2133fd57b913e91 163 Pfam PF01250 Ribosomal protein S6 4 92 2.4E-25 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25910 c4e374f5b594403cf2133fd57b913e91 163 Gene3D G3DSA:3.30.70.60 1 104 7.3E-33 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CAK95_RS06835 a5872e307ce434e7a0a5cdf185cc7a8a 238 Pfam PF10615 Protein of unknown function (DUF2470) 159 230 1.8E-11 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK95_RS06835 a5872e307ce434e7a0a5cdf185cc7a8a 238 Gene3D G3DSA:3.20.180.10 150 234 9.7E-30 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK95_RS06835 a5872e307ce434e7a0a5cdf185cc7a8a 238 Gene3D G3DSA:2.30.110.10 2 146 2.5E-45 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS06835 a5872e307ce434e7a0a5cdf185cc7a8a 238 SUPERFAMILY SSF50475 11 236 1.41E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS06835 a5872e307ce434e7a0a5cdf185cc7a8a 238 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 98 3.8E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS04050 0a31c5a4efee1f5182ab4fad189c39e1 133 Pfam PF00293 NUDIX domain 8 126 1.8E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS04050 0a31c5a4efee1f5182ab4fad189c39e1 133 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS04050 0a31c5a4efee1f5182ab4fad189c39e1 133 Gene3D G3DSA:3.90.79.10 7 124 5.5E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS04050 0a31c5a4efee1f5182ab4fad189c39e1 133 SUPERFAMILY SSF55811 7 126 1.49E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS08795 82114463148219dc3911488ea295f199 391 Gene3D G3DSA:3.20.20.30 36 378 3.1E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS08795 82114463148219dc3911488ea295f199 391 SUPERFAMILY SSF51679 40 378 1.15E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS08795 82114463148219dc3911488ea295f199 391 Pfam PF00296 Luciferase-like monooxygenase 43 341 2.1E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS20820 70c359cef78901e1058b81f3e0212b53 490 SUPERFAMILY SSF56784 73 165 1.4E-6 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20820 70c359cef78901e1058b81f3e0212b53 490 SUPERFAMILY SSF56784 21 33 1.4E-6 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20820 70c359cef78901e1058b81f3e0212b53 490 Pfam PF01040 UbiA prenyltransferase family 232 457 2.7E-21 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK95_RS14220 6cbe57e3808250077b6121852d2dd6e2 184 SUPERFAMILY SSF55729 3 153 1.82E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS14220 6cbe57e3808250077b6121852d2dd6e2 184 Pfam PF13302 Acetyltransferase (GNAT) domain 8 143 4.4E-20 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS14220 6cbe57e3808250077b6121852d2dd6e2 184 Gene3D G3DSA:3.40.630.30 3 178 1.1E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 SUPERFAMILY SSF46894 132 228 8.5E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 6 229 1.2E-104 T 06-07-2017 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 Gene3D G3DSA:3.40.50.2300 2 129 4.2E-43 T 06-07-2017 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 SMART SM00448 6 119 3.0E-46 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 Gene3D G3DSA:1.10.10.10 133 229 3.0E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 SUPERFAMILY SSF52172 4 129 1.35E-43 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 Pfam PF00072 Response regulator receiver domain 8 120 1.9E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 SMART SM00862 153 228 2.1E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS05865 4ac5a5fe16ca86f6009c993a59964d13 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 1.4E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 SMART SM00646 254 410 1.6E-34 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 Pfam PF11741 AMIN domain 48 148 3.9E-12 T 06-07-2017 IPR021731 AMIN domain CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 Gene3D G3DSA:3.40.630.40 338 414 2.6E-51 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 Gene3D G3DSA:3.40.630.40 192 291 2.6E-51 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 193 410 3.0E-46 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 SUPERFAMILY SSF53187 337 413 2.95E-48 T 06-07-2017 CAK95_RS25065 5c3983232ad1d7d6110f3954f7fb7fb0 428 SUPERFAMILY SSF53187 191 290 2.95E-48 T 06-07-2017 CAK95_RS07205 6340c1cecb0e51796af06a4502551d7e 176 SUPERFAMILY SSF53597 1 175 1.83E-23 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS07205 6340c1cecb0e51796af06a4502551d7e 176 Gene3D G3DSA:3.40.430.10 3 174 1.4E-20 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS07205 6340c1cecb0e51796af06a4502551d7e 176 Pfam PF01872 RibD C-terminal domain 3 168 1.4E-14 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 485 492 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 PIRSF PIRSF000774 1 507 2.4E-148 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 393 412 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 Pfam PF04552 Sigma-54, DNA binding domain 346 505 4.8E-70 T 06-07-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 504 2.0E-130 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 Pfam PF04963 Sigma-54 factor, core binding domain 144 331 2.6E-51 T 06-07-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 2.3E-17 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 PRINTS PR00045 Sigma-54 factor signature 405 417 3.4E-30 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 PRINTS PR00045 Sigma-54 factor signature 217 234 3.4E-30 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 PRINTS PR00045 Sigma-54 factor signature 480 498 3.4E-30 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05240 10744049144ad47e52eb59c1d96bdf17 514 PRINTS PR00045 Sigma-54 factor signature 421 432 3.4E-30 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 Gene3D G3DSA:3.50.50.60 293 319 2.0E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 Gene3D G3DSA:3.50.50.60 3 183 2.0E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 7.9E-19 T 06-07-2017 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 7.9E-19 T 06-07-2017 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 7.9E-19 T 06-07-2017 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 7.9E-19 T 06-07-2017 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 393 1.1E-122 T 06-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 Pfam PF01494 FAD binding domain 6 319 5.4E-30 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 SUPERFAMILY SSF51905 6 180 7.97E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 SUPERFAMILY SSF51905 270 388 7.97E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 Gene3D G3DSA:3.30.9.10 236 292 1.0E-4 T 06-07-2017 CAK95_RS08555 75d4c1c7b0bd2b98eff0d2105bdcd32b 407 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 297 310 - T 06-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 Gene3D G3DSA:1.20.140.10 278 434 6.6E-39 T 06-07-2017 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 393 412 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 SUPERFAMILY SSF56645 57 288 1.96E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 279 434 2.2E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 269 1.9E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 Gene3D G3DSA:2.40.110.10 176 270 1.1E-22 T 06-07-2017 CAK95_RS22095 32c9dabe62f74cd4984710e49a8db8c4 537 SUPERFAMILY SSF47203 277 435 1.13E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 SUPERFAMILY SSF103088 381 491 7.32E-30 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 SUPERFAMILY SSF140804 49 147 3.4E-19 T 06-07-2017 IPR027405 YidB-like CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 Pfam PF06078 Bacterial protein of unknown function (DUF937) 48 143 1.5E-7 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 Pfam PF00691 OmpA family 393 488 9.4E-19 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 Gene3D G3DSA:3.30.1330.60 387 494 3.5E-31 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 Gene3D G3DSA:1.10.10.690 36 147 1.3E-20 T 06-07-2017 IPR027405 YidB-like CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 PRINTS PR01021 OMPA domain signature 439 455 1.1E-6 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS17045 65b9c9a928fdae990cc27aa1ddcfe844 506 PRINTS PR01021 OMPA domain signature 424 439 1.1E-6 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS09315 34ba89937927e6ea7392c2e904e2c1a6 438 SUPERFAMILY SSF103473 24 432 6.28E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS09315 34ba89937927e6ea7392c2e904e2c1a6 438 Gene3D G3DSA:1.20.1250.20 225 436 9.2E-9 T 06-07-2017 CAK95_RS09315 34ba89937927e6ea7392c2e904e2c1a6 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK95_RS09315 34ba89937927e6ea7392c2e904e2c1a6 438 Pfam PF07690 Major Facilitator Superfamily 35 391 1.2E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS09315 34ba89937927e6ea7392c2e904e2c1a6 438 Gene3D G3DSA:1.20.1250.20 37 221 3.0E-14 T 06-07-2017 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 4 245 2.7E-66 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 Gene3D G3DSA:1.20.120.220 79 246 1.5E-49 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 PRINTS PR00123 ATP synthase A subunit signature 87 103 7.0E-30 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 PRINTS PR00123 ATP synthase A subunit signature 148 163 7.0E-30 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 PRINTS PR00123 ATP synthase A subunit signature 168 190 7.0E-30 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 PRINTS PR00123 ATP synthase A subunit signature 228 243 7.0E-30 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 ProSitePatterns PS00449 ATP synthase a subunit signature. 171 180 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 SUPERFAMILY SSF81336 78 242 7.85E-46 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 Pfam PF00119 ATP synthase A chain 32 241 6.3E-53 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS05545 63ebfedbc5d96f72fa3d5b35f7fd05f7 249 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 248 15.957 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 Gene3D G3DSA:3.90.1150.10 136 168 6.1E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 Gene3D G3DSA:3.90.1150.10 428 519 6.1E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 Gene3D G3DSA:3.40.640.10 187 422 1.0E-55 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 337 373 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 SUPERFAMILY SSF53383 134 521 4.45E-65 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 Pfam PF00202 Aminotransferase class-III 134 244 1.5E-11 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS00720 9228591c7f6cdb7255b2b31f4d0afc90 555 Pfam PF00202 Aminotransferase class-III 319 517 2.4E-21 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS02865 b34ea3163660bdb493640d9ac764d76a 206 Pfam PF08857 Putative ParB-like nuclease 12 166 1.6E-55 T 06-07-2017 IPR014956 Putative ParB-like nuclease CAK95_RS02865 b34ea3163660bdb493640d9ac764d76a 206 PIRSF PIRSF029669 1 205 9.0E-86 T 06-07-2017 IPR016932 Uncharacterised conserved protein UCP029669 CAK95_RS02865 b34ea3163660bdb493640d9ac764d76a 206 SUPERFAMILY SSF110849 6 203 5.75E-71 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS02865 b34ea3163660bdb493640d9ac764d76a 206 Gene3D G3DSA:1.10.8.10 135 194 5.5E-20 T 06-07-2017 CAK95_RS02865 b34ea3163660bdb493640d9ac764d76a 206 Gene3D G3DSA:3.90.1530.10 6 134 4.5E-44 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Gene3D G3DSA:3.30.300.30 441 539 3.1E-33 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Gene3D G3DSA:3.40.50.980 20 133 8.0E-32 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Gene3D G3DSA:3.40.50.980 174 198 8.0E-32 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Gene3D G3DSA:2.30.38.10 372 436 5.0E-17 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 SUPERFAMILY SSF56801 15 541 1.18E-137 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Gene3D G3DSA:3.40.50.980 199 346 5.5E-29 T 06-07-2017 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Pfam PF00501 AMP-binding enzyme 26 446 7.0E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS04335 7f412caa395f93566cd8a15f30f27d74 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 529 7.3E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Gene3D G3DSA:3.30.70.260 847 915 1.3E-15 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Gene3D G3DSA:3.30.70.260 739 787 1.7E-5 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 54 918 1.3E-289 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SMART SM00471 495 643 8.5E-5 T 06-07-2017 IPR003607 HD/PDEase domain CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Pfam PF01842 ACT domain 850 898 1.4E-6 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SUPERFAMILY SSF55021 846 921 1.45E-13 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SUPERFAMILY SSF81301 7 206 1.24E-32 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Pfam PF01909 Nucleotidyltransferase domain 105 133 7.6E-5 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Gene3D G3DSA:1.10.3210.10 469 665 5.3E-31 T 06-07-2017 IPR006674 HD domain CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 933 301.677 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Gene3D G3DSA:3.30.460.10 121 198 1.4E-8 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Pfam PF08335 GlnD PII-uridylyltransferase 212 350 2.6E-33 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 PIRSF PIRSF006288 30 929 0.0 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SUPERFAMILY SSF81891 401 643 3.18E-20 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SUPERFAMILY SSF81593 226 343 8.63E-10 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Pfam PF01966 HD domain 500 619 2.5E-11 T 06-07-2017 IPR006674 HD domain CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 Gene3D G3DSA:3.30.460.10 70 120 6.4E-4 T 06-07-2017 CAK95_RS06285 f21d0c4dc1c42613610aa459f2ed70e7 935 SUPERFAMILY SSF55021 737 805 7.08E-9 T 06-07-2017 CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SMART SM00052 339 586 8.1E-85 T 06-07-2017 IPR001633 EAL domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Gene3D G3DSA:3.30.70.270 173 334 1.3E-35 T 06-07-2017 CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Pfam PF00563 EAL domain 345 581 1.5E-66 T 06-07-2017 IPR001633 EAL domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SUPERFAMILY SSF55073 177 329 2.28E-30 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 170 326 6.4E-26 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SUPERFAMILY SSF55781 19 172 3.71E-22 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SMART SM00065 18 169 1.0E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Gene3D G3DSA:3.20.20.450 345 591 3.3E-74 T 06-07-2017 IPR001633 EAL domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Gene3D G3DSA:3.30.450.40 4 171 3.3E-16 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Pfam PF00990 Diguanylate cyclase, GGDEF domain 172 324 5.5E-29 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 Pfam PF13185 GAF domain 19 160 1.8E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SMART SM00267 161 329 1.1E-33 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS19275 0d871512f1e11e60be9fe0caeb103095 646 SUPERFAMILY SSF141868 345 593 4.84E-70 T 06-07-2017 IPR001633 EAL domain CAK95_RS15845 7e1b1db7052fe3ba28601137764b6fd7 209 Gene3D G3DSA:2.30.110.10 25 150 5.2E-19 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS15845 7e1b1db7052fe3ba28601137764b6fd7 209 SUPERFAMILY SSF50475 11 140 7.36E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS15845 7e1b1db7052fe3ba28601137764b6fd7 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 209 1.6E-61 T 06-07-2017 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CAK95_RS15845 7e1b1db7052fe3ba28601137764b6fd7 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 38 124 2.7E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 SUPERFAMILY SSF52029 184 376 3.31E-84 T 06-07-2017 IPR027409 GroEL-like apical domain CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 Gene3D G3DSA:1.10.560.10 3 188 2.7E-47 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 SUPERFAMILY SSF48592 406 522 2.44E-77 T 06-07-2017 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 SUPERFAMILY SSF48592 7 134 2.44E-77 T 06-07-2017 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 Gene3D G3DSA:1.10.560.10 367 519 1.2E-40 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 Gene3D G3DSA:3.50.7.10 189 366 6.3E-101 T 06-07-2017 IPR027409 GroEL-like apical domain CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 528 3.6E-258 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-75 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-75 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-75 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-75 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-75 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 42.305 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 SUPERFAMILY SSF54849 137 204 7.33E-24 T 06-07-2017 CAK95_RS13155 8a0bbe8c3b28635ca8b3350ce5009ec0 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 1.8E-98 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAK95_RS28905 65a9159d5a7d9c1dd3e8747773fa7331 111 Pfam PF07978 NIPSNAP 7 104 8.9E-17 T 06-07-2017 IPR012577 NIPSNAP CAK95_RS28905 65a9159d5a7d9c1dd3e8747773fa7331 111 SUPERFAMILY SSF54909 4 104 6.44E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS28905 65a9159d5a7d9c1dd3e8747773fa7331 111 Gene3D G3DSA:3.30.70.900 4 104 1.6E-10 T 06-07-2017 CAK95_RS27570 bf640fd7c0490d3b636f3bb4a60fc42c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS27570 bf640fd7c0490d3b636f3bb4a60fc42c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS27570 bf640fd7c0490d3b636f3bb4a60fc42c 194 SUPERFAMILY SSF46689 3 85 3.4E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27570 bf640fd7c0490d3b636f3bb4a60fc42c 194 Gene3D G3DSA:1.10.357.10 6 188 2.0E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS27570 bf640fd7c0490d3b636f3bb4a60fc42c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF143517 1010 1160 8.11E-42 T 06-07-2017 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Gene3D G3DSA:3.30.2060.10 141 215 5.5E-14 T 06-07-2017 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF52540 796 1004 5.44E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SMART SM00982 1020 1120 1.3E-43 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1093 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Gene3D G3DSA:3.40.50.300 816 977 1.4E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SMART SM01058 494 590 9.1E-44 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Pfam PF00270 DEAD/DEAH box helicase 619 776 1.5E-15 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Pfam PF03461 TRCF domain 1023 1114 8.2E-27 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Pfam PF00271 Helicase conserved C-terminal domain 819 923 4.3E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Gene3D G3DSA:3.40.50.300 602 800 6.1E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SMART SM00490 837 924 3.0E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF52540 8 357 1.73E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SMART SM00487 614 804 3.4E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 33 1154 28.271 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF141259 486 562 6.54E-21 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF52540 538 798 1.27E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 Pfam PF02559 CarD-like/TRCF domain 495 587 5.8E-25 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS23625 425aaa630c96e2575af6a3fb531807ff 1167 SUPERFAMILY SSF52540 364 485 3.45E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03125 c5ba42b282059fa45bf750c61934af3a 427 Gene3D G3DSA:3.90.226.10 38 165 1.6E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS03125 c5ba42b282059fa45bf750c61934af3a 427 Gene3D G3DSA:3.90.226.10 206 278 1.6E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS03125 c5ba42b282059fa45bf750c61934af3a 427 SUPERFAMILY SSF52096 207 266 1.39E-27 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS03125 c5ba42b282059fa45bf750c61934af3a 427 SUPERFAMILY SSF52096 53 176 1.39E-27 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS03125 c5ba42b282059fa45bf750c61934af3a 427 Pfam PF01343 Peptidase family S49 131 275 5.5E-31 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CAK95_RS08600 57e77e8b73c1739e3076a885d632b0db 258 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 97 251 3.1E-37 T 06-07-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CAK95_RS08600 57e77e8b73c1739e3076a885d632b0db 258 Gene3D G3DSA:2.50.20.10 87 252 2.5E-25 T 06-07-2017 CAK95_RS08600 57e77e8b73c1739e3076a885d632b0db 258 SUPERFAMILY SSF89392 87 252 3.77E-27 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 SUPERFAMILY SSF52540 24 257 2.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 24 270 1.4E-121 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 SMART SM00382 47 246 4.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 Pfam PF00005 ABC transporter 38 194 1.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05875 4c894c3cc8c2338ebb390ce83931924b 270 Gene3D G3DSA:3.40.50.300 18 263 2.6E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 Gene3D G3DSA:3.60.20.10 15 185 8.1E-83 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 14 184 40.2 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 15 184 2.3E-81 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 PIRSF PIRSF039093 8 187 5.3E-83 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 Pfam PF00227 Proteasome subunit 13 183 1.6E-19 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAK95_RS08010 f8ac8538d6ce7555f2110125af2ffc4e 187 SUPERFAMILY SSF56235 11 184 4.27E-56 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Gene3D G3DSA:2.40.110.10 148 245 1.4E-33 T 06-07-2017 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Gene3D G3DSA:1.10.540.10 37 147 2.6E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Gene3D G3DSA:1.20.140.10 246 405 2.4E-55 T 06-07-2017 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 37 145 3.2E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 362 381 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 SUPERFAMILY SSF56645 36 268 1.18E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 SUPERFAMILY SSF47203 254 406 9.18E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 149 243 2.4E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS07165 8e64160ea7d6348bb0d01460cd614a3f 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 255 402 2.0E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 SUPERFAMILY SSF53901 280 401 1.03E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 1.8E-124 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 PIRSF PIRSF000429 1 402 3.2E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 SUPERFAMILY SSF53901 3 279 5.03E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Pfam PF00108 Thiolase, N-terminal domain 11 229 2.0E-46 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Gene3D G3DSA:3.40.47.10 185 285 2.6E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Gene3D G3DSA:3.40.47.10 3 126 2.6E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Pfam PF02803 Thiolase, C-terminal domain 279 401 3.8E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Gene3D G3DSA:3.40.47.10 286 401 3.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS05590 6450cb5ecc21c802db304b119c628d87 402 Gene3D G3DSA:3.40.47.10 144 184 3.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 Gene3D G3DSA:3.90.76.10 42 194 2.3E-34 T 06-07-2017 CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 Gene3D G3DSA:3.40.190.10 195 292 7.6E-25 T 06-07-2017 CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 SUPERFAMILY SSF53850 29 523 5.52E-106 T 06-07-2017 CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 Gene3D G3DSA:3.10.105.10 293 492 1.6E-37 T 06-07-2017 CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 439 4.5E-69 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS11490 72836c5a7d3d2e5ab089833cb98bbc94 526 PIRSF PIRSF002741 2 524 1.3E-76 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.006 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 SUPERFAMILY SSF46946 2 121 2.22E-45 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.8E-31 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 Gene3D G3DSA:4.10.910.10 73 122 2.3E-29 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 PIRSF PIRSF002134 1 122 2.2E-44 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 Gene3D G3DSA:1.10.8.50 2 72 7.9E-28 T 06-07-2017 CAK95_RS21375 d5f101f0797f9f3fd379408ebed38b48 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 3.9E-53 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS13905 0d934986123e6aae4283ebb9a2453f5d 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.894 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK95_RS13905 0d934986123e6aae4283ebb9a2453f5d 176 SUPERFAMILY SSF50324 4 175 1.16E-65 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK95_RS13905 0d934986123e6aae4283ebb9a2453f5d 176 Gene3D G3DSA:3.90.80.10 5 175 4.4E-57 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK95_RS13905 0d934986123e6aae4283ebb9a2453f5d 176 Pfam PF00719 Inorganic pyrophosphatase 18 173 1.2E-52 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 2.1E-165 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 Gene3D G3DSA:3.65.10.10 21 222 2.2E-62 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 44.581 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 Gene3D G3DSA:3.65.10.10 223 418 9.7E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 SUPERFAMILY SSF55205 1 418 3.43E-127 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAK95_RS00760 3b0c8bd43e933d24f0785fe8dce68851 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 2.8E-94 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS24135 ad109dce8f5cfd09cc32faef2624d5ca 126 Gene3D G3DSA:1.20.1290.10 36 123 1.3E-21 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS24135 ad109dce8f5cfd09cc32faef2624d5ca 126 SUPERFAMILY SSF69118 5 121 8.51E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS24135 ad109dce8f5cfd09cc32faef2624d5ca 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 3.1E-22 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 SMART SM00357 3 66 1.6E-24 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-25 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 PIRSF PIRSF002599 1 66 1.1E-22 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 Gene3D G3DSA:2.40.50.140 3 65 2.7E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 PRINTS PR00050 Cold shock protein signature 40 58 1.6E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 SUPERFAMILY SSF50249 2 65 8.57E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04535 5f23cc7d40b38ef4d9a4dd85f8145534 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Pfam PF01938 TRAM domain 376 441 4.0E-6 T 06-07-2017 IPR002792 TRAM domain CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 6 438 1.0E-164 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 SUPERFAMILY SSF102114 120 370 3.92E-47 T 06-07-2017 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Pfam PF04055 Radical SAM superfamily 142 323 5.8E-27 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 SMART SM00729 136 365 1.2E-48 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 440 58.787 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Pfam PF00919 Uncharacterized protein family UPF0004 6 99 2.9E-19 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 7 438 9.6E-100 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Gene3D G3DSA:2.40.50.140 380 441 4.2E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 Gene3D G3DSA:3.80.30.20 134 377 1.0E-68 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS23520 a3f26dbcdc58ea43ff18d76ce76e3433 443 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 140 160 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAK95_RS05050 d88e3623d0e04dd4beda9b1b934737c8 492 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 150 351 1.8E-24 T 06-07-2017 IPR004299 Membrane bound O-acyl transferase, MBOAT CAK95_RS05050 d88e3623d0e04dd4beda9b1b934737c8 492 PIRSF PIRSF500217 1 492 5.7E-148 T 06-07-2017 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CAK95_RS05050 d88e3623d0e04dd4beda9b1b934737c8 492 PIRSF PIRSF016636 1 492 5.4E-147 T 06-07-2017 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CAK95_RS27940 57489f4262e5c761b5435051028eb253 374 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 12 253 6.1E-81 T 06-07-2017 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CAK95_RS27940 57489f4262e5c761b5435051028eb253 374 SUPERFAMILY SSF53850 55 258 1.12E-37 T 06-07-2017 CAK95_RS27940 57489f4262e5c761b5435051028eb253 374 Gene3D G3DSA:3.40.190.10 120 241 1.6E-7 T 06-07-2017 CAK95_RS27940 57489f4262e5c761b5435051028eb253 374 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 36 286 1.4E-59 T 06-07-2017 CAK95_RS27940 57489f4262e5c761b5435051028eb253 374 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 14 298 1.5E-95 T 06-07-2017 IPR017797 Phosphonate ABC transporter, periplasmic substrate-binding protein GO:0015604|GO:0015716|GO:0043190 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 15 373 4.0E-95 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 Gene3D G3DSA:3.40.50.620 10 222 1.9E-79 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 Gene3D G3DSA:2.30.30.280 229 284 1.7E-18 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 SUPERFAMILY SSF52402 13 257 1.19E-51 T 06-07-2017 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 14 374 38.737 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 Gene3D G3DSA:2.40.30.10 288 377 1.1E-17 T 06-07-2017 CAK95_RS15375 306682fb40ae93accc14753d42266a78 397 Pfam PF03054 tRNA methyl transferase 15 373 5.7E-109 T 06-07-2017 CAK95_RS24700 21de567b4598b1ca2d79f580c8a115c7 105 Pfam PF11011 Protein of unknown function (DUF2849) 16 98 3.0E-25 T 06-07-2017 IPR021270 Protein of unknown function DUF2849 CAK95_RS27920 aa7a496b4f226e39fbfacc8336f01c81 199 PIRSF PIRSF020680 1 199 3.4E-63 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAK95_RS27920 aa7a496b4f226e39fbfacc8336f01c81 199 SUPERFAMILY SSF159709 15 196 4.71E-60 T 06-07-2017 CAK95_RS27920 aa7a496b4f226e39fbfacc8336f01c81 199 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 9 194 3.6E-58 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAK95_RS27920 aa7a496b4f226e39fbfacc8336f01c81 199 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 7 196 2.4E-65 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 SUPERFAMILY SSF46689 260 308 2.82E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 Gene3D G3DSA:1.10.10.60 206 261 1.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 SMART SM00342 224 307 1.1E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 3.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 3.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 SUPERFAMILY SSF46689 209 258 4.03E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 Pfam PF12833 Helix-turn-helix domain 230 308 1.1E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS18250 95017d1637f59b37b6ffec1937832d91 312 Gene3D G3DSA:1.10.10.60 262 305 2.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 Gene3D G3DSA:3.40.190.10 190 240 2.5E-6 T 06-07-2017 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 Gene3D G3DSA:3.40.190.10 91 189 4.9E-19 T 06-07-2017 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 Gene3D G3DSA:1.10.10.10 5 85 1.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 SUPERFAMILY SSF53850 92 285 5.12E-28 T 06-07-2017 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 SUPERFAMILY SSF46785 6 113 3.46E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 Pfam PF03466 LysR substrate binding domain 92 282 1.3E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS09430 0b5bdc7e2def2bc9ff1b413852900355 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 6 433 3.4E-162 T 06-07-2017 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 Pfam PF01134 Glucose inhibited division protein A 7 378 1.9E-107 T 06-07-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 7 465 34.693 T 06-07-2017 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 Gene3D G3DSA:3.50.50.60 7 141 9.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 Gene3D G3DSA:3.50.50.60 247 248 9.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 Gene3D G3DSA:3.50.50.60 329 375 9.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 349 372 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CAK95_RS23845 a7ed433f1e11ce5b307991e599eadde1 472 SUPERFAMILY SSF51905 3 374 3.42E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00035 24cd01cc65af3b41825fbf06609faed5 82 Gene3D G3DSA:3.10.450.50 15 71 4.2E-6 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS00035 24cd01cc65af3b41825fbf06609faed5 82 SUPERFAMILY SSF54427 8 74 6.08E-7 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS01490 a33bbd8dac5d59523d78fbec9a2e7b72 76 Pfam PF13358 DDE superfamily endonuclease 3 35 4.5E-8 T 06-07-2017 CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 68 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 3.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 Gene3D G3DSA:1.10.357.10 13 191 7.8E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14865 68394c5e29da338c77df02b4e64a4f55 215 SUPERFAMILY SSF46689 14 94 2.64E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 37 92 1.7E-6 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Pfam PF00501 AMP-binding enzyme 102 525 4.0E-45 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 613 2.5E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 650 3.3E-303 T 06-07-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Gene3D G3DSA:3.40.50.980 275 432 1.9E-15 T 06-07-2017 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 SUPERFAMILY SSF56801 20 641 5.23E-123 T 06-07-2017 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Gene3D G3DSA:3.40.50.980 89 274 1.1E-25 T 06-07-2017 CAK95_RS03815 2a0a2cc51d6d78b9b7c58be0ae19b6ed 651 Gene3D G3DSA:3.30.300.30 526 632 9.3E-17 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Gene3D G3DSA:3.40.50.980 176 323 2.2E-38 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 SUPERFAMILY SSF56801 6 515 6.41E-146 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Gene3D G3DSA:3.40.50.980 6 117 1.7E-34 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Gene3D G3DSA:3.40.50.980 151 175 1.7E-34 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Gene3D G3DSA:2.30.38.10 336 407 2.8E-28 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 502 3.7E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Gene3D G3DSA:3.30.300.30 412 513 5.6E-28 T 06-07-2017 CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS11450 d168fc5b7f22964e98d37bacd71a8883 521 Pfam PF00501 AMP-binding enzyme 11 417 1.2E-103 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 SMART SM00535 83 217 6.4E-45 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 ProSitePatterns PS00517 Ribonuclease III family signature. 105 113 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 Gene3D G3DSA:1.10.1520.10 69 209 5.9E-40 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 Hamap MF_00104 Ribonuclease 3 [rnc]. 71 284 28.696 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 Pfam PF14622 Ribonuclease-III-like 81 207 8.5E-31 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 Gene3D G3DSA:3.30.160.20 220 286 1.6E-25 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 72 286 1.3E-71 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 SUPERFAMILY SSF69065 67 223 1.96E-44 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 SUPERFAMILY SSF54768 178 291 3.64E-28 T 06-07-2017 CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 SMART SM00358 221 288 8.7E-26 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS22350 570c6dc67e3f866b9a1522855603d5e1 293 Pfam PF00035 Double-stranded RNA binding motif 221 285 1.5E-16 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 18 25 - T 06-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 PRINTS PR00107 Phosphocarrier protein signature 58 75 9.1E-12 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 PRINTS PR00107 Phosphocarrier protein signature 43 58 9.1E-12 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 PRINTS PR00107 Phosphocarrier protein signature 18 34 9.1E-12 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 Pfam PF00381 PTS HPr component phosphorylation site 9 86 1.7E-24 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 9 86 4.3E-26 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 SUPERFAMILY SSF55594 9 93 2.49E-25 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS06860 f0ab96ba6cc2e5fd15e25fb2e4a39652 94 Gene3D G3DSA:3.30.1340.10 9 92 1.6E-27 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 Pfam PF00571 CBS domain 192 241 8.8E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 Pfam PF00571 CBS domain 96 152 3.2E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 SUPERFAMILY SSF54631 90 256 2.65E-32 T 06-07-2017 CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 SMART SM01091 257 340 4.5E-18 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 SMART SM00116 193 241 0.27 T 06-07-2017 IPR000644 CBS domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 SMART SM00116 104 153 0.05 T 06-07-2017 IPR000644 CBS domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 Pfam PF03471 Transporter associated domain 258 337 1.3E-16 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 SUPERFAMILY SSF56176 254 340 2.73E-17 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 Gene3D G3DSA:3.10.580.10 83 249 1.2E-17 T 06-07-2017 CAK95_RS09210 e82d085c32d51ac6022a637de7671a15 374 Gene3D G3DSA:3.30.465.10 250 337 5.1E-22 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 Pfam PF00313 'Cold-shock' DNA-binding domain 4 68 1.4E-23 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 Gene3D G3DSA:2.40.50.140 3 68 4.8E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 PRINTS PR00050 Cold shock protein signature 26 35 1.9E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 PRINTS PR00050 Cold shock protein signature 41 59 1.9E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 PRINTS PR00050 Cold shock protein signature 5 20 1.9E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 SMART SM00357 4 70 2.4E-24 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 SUPERFAMILY SSF50249 3 70 8.57E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS01615 fb0c68c9db2be94b061a3a06becfed00 71 PIRSF PIRSF002599 1 71 1.9E-22 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK95_RS03630 898d1482b08501f45f0527a45e762f3d 425 Gene3D G3DSA:3.40.50.1390 16 153 5.4E-35 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03630 898d1482b08501f45f0527a45e762f3d 425 SUPERFAMILY SSF53041 16 170 1.44E-39 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03630 898d1482b08501f45f0527a45e762f3d 425 Pfam PF00239 Resolvase, N terminal domain 18 168 1.4E-39 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03630 898d1482b08501f45f0527a45e762f3d 425 Pfam PF07508 Recombinase 191 276 9.3E-12 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK95_RS03630 898d1482b08501f45f0527a45e762f3d 425 SMART SM00857 17 170 9.2E-62 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS03870 b555114de064b29e7b3cb1ce2cc2ff6d 288 Pfam PF00117 Glutamine amidotransferase class-I 63 206 2.1E-16 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS03870 b555114de064b29e7b3cb1ce2cc2ff6d 288 Gene3D G3DSA:3.40.50.880 61 222 2.9E-32 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS03870 b555114de064b29e7b3cb1ce2cc2ff6d 288 SUPERFAMILY SSF52317 62 219 7.69E-33 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS09270 061672bb3a37e53159373550e503474a 332 Gene3D G3DSA:3.40.1190.20 5 321 9.2E-74 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS09270 061672bb3a37e53159373550e503474a 332 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 274 287 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAK95_RS09270 061672bb3a37e53159373550e503474a 332 Pfam PF00294 pfkB family carbohydrate kinase 56 318 2.7E-51 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK95_RS09270 061672bb3a37e53159373550e503474a 332 SUPERFAMILY SSF53613 5 319 9.35E-82 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS21640 2547a901b64c6cae4060fe19de8dae68 313 Pfam PF04199 Putative cyclase 26 233 8.7E-23 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS21640 2547a901b64c6cae4060fe19de8dae68 313 SUPERFAMILY SSF102198 125 307 5.89E-25 T 06-07-2017 CAK95_RS21640 2547a901b64c6cae4060fe19de8dae68 313 SUPERFAMILY SSF102198 23 94 5.89E-25 T 06-07-2017 CAK95_RS21640 2547a901b64c6cae4060fe19de8dae68 313 Gene3D G3DSA:3.50.30.50 22 95 8.7E-36 T 06-07-2017 CAK95_RS21640 2547a901b64c6cae4060fe19de8dae68 313 Gene3D G3DSA:3.50.30.50 129 308 8.7E-36 T 06-07-2017 CAK95_RS13335 71433fd997e55b6e04fe6f63bb560015 95 Pfam PF01541 GIY-YIG catalytic domain 5 75 4.3E-11 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS13335 71433fd997e55b6e04fe6f63bb560015 95 Gene3D G3DSA:3.40.1440.10 3 39 5.6E-4 T 06-07-2017 IPR027299 GIY-YIG domain CAK95_RS13335 71433fd997e55b6e04fe6f63bb560015 95 SUPERFAMILY SSF82771 3 90 3.53E-17 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SUPERFAMILY SSF54980 400 478 2.27E-22 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SUPERFAMILY SSF52540 7 281 6.64E-109 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SMART SM00889 478 596 4.1E-64 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SUPERFAMILY SSF54211 477 596 1.87E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Pfam PF00679 Elongation factor G C-terminus 598 682 8.5E-29 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.3E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.3E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.3E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.3E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.3E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 688 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Gene3D G3DSA:2.40.30.10 303 403 9.3E-37 T 06-07-2017 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 107.139 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 2.8E-37 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 2.4E-70 T 06-07-2017 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Pfam PF03144 Elongation factor Tu domain 2 322 389 8.1E-17 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Gene3D G3DSA:3.30.70.870 404 478 6.0E-36 T 06-07-2017 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SUPERFAMILY SSF50447 264 402 4.24E-37 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Gene3D G3DSA:3.30.70.240 597 682 1.4E-32 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SMART SM00838 598 685 7.6E-52 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Pfam PF03764 Elongation factor G, domain IV 477 595 1.3E-43 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Gene3D G3DSA:3.30.230.10 482 596 8.7E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Pfam PF14492 Elongation Factor G, domain II 402 475 5.7E-32 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 Gene3D G3DSA:3.40.50.300 7 286 2.3E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21250 1a519aea971e465099302f92d64685e4 690 SUPERFAMILY SSF54980 598 685 1.63E-28 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 Pfam PF06472 ABC transporter transmembrane region 2 8 294 4.6E-56 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 Pfam PF00005 ABC transporter 389 520 3.3E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 SMART SM00382 394 565 4.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 Gene3D G3DSA:3.40.50.300 371 563 2.5E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 SUPERFAMILY SSF52540 371 562 3.65E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 SUPERFAMILY SSF90123 25 341 1.7E-17 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS15915 fb2f99288dd115ee6fcc606edd01f1e4 584 Gene3D G3DSA:1.20.1560.10 17 341 6.7E-8 T 06-07-2017 CAK95_RS25840 e54b41e008e6f233162a7787788d5131 358 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 352 1.4E-60 T 06-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 CAK95_RS25840 e54b41e008e6f233162a7787788d5131 358 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 2 354 2.9E-93 T 06-07-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 CAK95_RS04095 ad82c1f83d6e156c33de1aaed56af335 185 Pfam PF01613 Flavin reductase like domain 20 163 2.4E-21 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS04095 ad82c1f83d6e156c33de1aaed56af335 185 Gene3D G3DSA:2.30.110.10 5 175 2.7E-47 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS04095 ad82c1f83d6e156c33de1aaed56af335 185 SMART SM00903 16 168 5.9E-16 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS04095 ad82c1f83d6e156c33de1aaed56af335 185 SUPERFAMILY SSF50475 3 172 4.27E-41 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS09185 9617d42abf65d12c553c2c8cfb699f5f 363 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 94 350 4.8E-63 T 06-07-2017 IPR019285 Protein of unknown function DUF2336 CAK95_RS28175 254273dab6c6a4c8833ed2dfc87e7ad1 334 PIRSF PIRSF001439 2 334 1.9E-85 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS28175 254273dab6c6a4c8833ed2dfc87e7ad1 334 Gene3D G3DSA:3.30.1780.10 6 145 1.1E-35 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAK95_RS28175 254273dab6c6a4c8833ed2dfc87e7ad1 334 Gene3D G3DSA:3.40.50.720 146 304 4.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28175 254273dab6c6a4c8833ed2dfc87e7ad1 334 SUPERFAMILY SSF51735 5 332 1.81E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28175 254273dab6c6a4c8833ed2dfc87e7ad1 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 10 322 4.4E-59 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS06730 182bbac055f227986afc947686162b59 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 179 2.9E-28 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS06730 182bbac055f227986afc947686162b59 339 Gene3D G3DSA:3.90.25.10 206 294 8.7E-5 T 06-07-2017 CAK95_RS06730 182bbac055f227986afc947686162b59 339 SUPERFAMILY SSF51735 1 295 4.18E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06730 182bbac055f227986afc947686162b59 339 Gene3D G3DSA:3.40.50.720 1 205 3.9E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SUPERFAMILY SSF55874 394 563 1.57E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Pfam PF02743 Cache domain 62 217 5.2E-17 T 06-07-2017 IPR033479 Double Cache domain 1 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Gene3D G3DSA:3.30.565.10 404 563 3.0E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SMART SM00448 585 695 1.2E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SUPERFAMILY SSF52172 586 701 1.99E-27 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SMART SM00388 339 404 2.8E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 1.0E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 1.0E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 522 1.0E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 1.0E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SMART SM00387 445 565 8.4E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 SUPERFAMILY SSF47384 332 402 1.49E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Pfam PF00072 Response regulator receiver domain 587 669 2.6E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Gene3D G3DSA:1.10.287.130 332 400 6.1E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Pfam PF00512 His Kinase A (phospho-acceptor) domain 341 402 1.8E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Gene3D G3DSA:3.30.450.20 86 185 2.6E-8 T 06-07-2017 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Gene3D G3DSA:3.40.50.2300 584 703 2.0E-31 T 06-07-2017 CAK95_RS20785 617cc7085db800aad7e0464cdb6f506f 709 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 563 5.3E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26480 832dba1e1a9b7e786b9028701d35ca80 155 Pfam PF01042 Endoribonuclease L-PSP 35 148 1.2E-16 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS26480 832dba1e1a9b7e786b9028701d35ca80 155 Gene3D G3DSA:3.30.1330.40 27 151 4.5E-25 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS26480 832dba1e1a9b7e786b9028701d35ca80 155 SUPERFAMILY SSF55298 28 151 2.2E-26 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Gene3D G3DSA:3.90.480.10 48 117 2.7E-38 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Gene3D G3DSA:3.90.480.10 321 403 2.7E-38 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 52 110 2.8E-18 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 333 398 1.5E-15 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 SUPERFAMILY SSF56014 120 280 8.51E-48 T 06-07-2017 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 SUPERFAMILY SSF55124 1 126 5.4E-31 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 SUPERFAMILY SSF55124 315 421 3.6E-25 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 SUPERFAMILY SSF55124 252 276 3.6E-25 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 272 1.3E-41 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 548 2.1E-12 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Gene3D G3DSA:3.30.413.10 408 549 2.8E-36 T 06-07-2017 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 Gene3D G3DSA:3.30.413.10 120 272 7.3E-43 T 06-07-2017 CAK95_RS24695 fe71f4a888b1e46002460fc0f08fed7b 552 SUPERFAMILY SSF56014 409 550 5.1E-40 T 06-07-2017 CAK95_RS27410 449314a9319ee1188bced01775abbef5 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 338 1.7E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27410 449314a9319ee1188bced01775abbef5 339 SUPERFAMILY SSF161098 95 163 5.63E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27410 449314a9319ee1188bced01775abbef5 339 SUPERFAMILY SSF161098 201 325 5.63E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27410 449314a9319ee1188bced01775abbef5 339 Gene3D G3DSA:1.10.3720.10 204 333 2.8E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27410 449314a9319ee1188bced01775abbef5 339 Gene3D G3DSA:1.10.3720.10 94 166 2.8E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 454 1.4E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 Gene3D G3DSA:1.10.287.130 243 301 1.9E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 Gene3D G3DSA:3.30.565.10 316 455 1.2E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 SMART SM00387 350 455 5.4E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 SUPERFAMILY SSF47384 231 302 4.51E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09345 dfe21698f0f6b50456baeef36d5a035f 465 SUPERFAMILY SSF55874 321 453 3.54E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 SUPERFAMILY SSF55874 29 231 3.8E-58 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Pfam PF00204 DNA gyrase B 252 422 2.2E-44 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 594 657 2.7E-24 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 SUPERFAMILY SSF56719 425 658 4.45E-75 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 SMART SM00433 58 661 5.4E-280 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Gene3D G3DSA:3.30.565.10 29 231 1.1E-75 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 SMART SM00387 54 200 8.2E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Gene3D G3DSA:3.40.50.670 435 648 9.1E-81 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Pfam PF01751 Toprim domain 450 554 3.0E-17 T 06-07-2017 IPR006171 Toprim domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 27 661 1.8E-233 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 58 73 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 517 533 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 598 614 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 451 465 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 93 106 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 137 151 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 555 567 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 535 552 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR00418 DNA topoisomerase II family signature 301 314 1.1E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 619 631 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 251 273 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 29 39 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 344 360 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 406 426 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 501 510 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 PRINTS PR01159 DNA gyrase subunit B signature 392 406 6.5E-18 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 54 199 1.3E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Gene3D G3DSA:3.30.230.10 251 423 5.6E-45 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 SUPERFAMILY SSF54211 252 423 6.83E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 26 665 41.974 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS24850 e1e5fc79803c7b885c24d4f55378ffa2 670 ProSitePatterns PS00177 DNA topoisomerase II signature. 453 461 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS28785 0dc2aec0d6503cb7eeafd4bc1a56bf6f 251 Pfam PF13358 DDE superfamily endonuclease 120 204 7.6E-13 T 06-07-2017 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 Gene3D G3DSA:2.170.130.10 24 140 1.1E-24 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 30 670 9.3E-105 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 Pfam PF07715 TonB-dependent Receptor Plug Domain 28 121 1.6E-12 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 Pfam PF00593 TonB dependent receptor 433 668 4.8E-27 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 Gene3D G3DSA:2.40.170.20 146 670 2.8E-106 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS05220 4a9f81206a49850566d53f2d4d425893 670 SUPERFAMILY SSF56935 23 670 1.33E-105 T 06-07-2017 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 SUPERFAMILY SSF46785 305 386 2.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Pfam PF03466 LysR substrate binding domain 394 602 2.8E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 334 344 4.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 344 355 4.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 323 334 4.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 SUPERFAMILY SSF46785 1 80 1.41E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Gene3D G3DSA:1.10.10.10 1 79 2.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 5.0E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 308 359 3.3E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Gene3D G3DSA:1.10.10.10 307 386 3.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Gene3D G3DSA:3.40.190.10 503 575 1.8E-13 T 06-07-2017 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 SUPERFAMILY SSF53850 413 603 3.1E-25 T 06-07-2017 CAK95_RS01165 58d3f84db0a755580e96930bf6234698 613 Gene3D G3DSA:3.40.190.10 387 502 3.4E-10 T 06-07-2017 CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 Pfam PF13872 P-loop containing NTP hydrolase pore-1 415 739 2.0E-117 T 06-07-2017 CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 Gene3D G3DSA:3.40.50.300 503 664 1.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 Pfam PF13871 C-terminal domain on Strawberry notch homologue 910 1166 8.0E-85 T 06-07-2017 IPR026937 Strawberry notch, helicase C domain CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 Gene3D G3DSA:3.40.50.150 141 257 8.3E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 SUPERFAMILY SSF52540 409 694 1.29E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19445 170c9ce3a1ab8e61653d9c9eb490a4ac 1444 SUPERFAMILY SSF53335 123 307 8.16E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 598 3.0E-280 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 SUPERFAMILY SSF54980 398 512 6.23E-27 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 SUPERFAMILY SSF54980 301 386 1.92E-12 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Gene3D G3DSA:2.40.30.10 203 301 1.4E-22 T 06-07-2017 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 SUPERFAMILY SSF50447 149 296 5.41E-28 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 SMART SM00838 395 483 0.0073 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Gene3D G3DSA:3.30.70.870 302 401 6.6E-34 T 06-07-2017 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Gene3D G3DSA:3.30.70.240 402 481 1.1E-29 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Pfam PF00009 Elongation factor Tu GTP binding domain 2 194 8.3E-59 T 06-07-2017 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Gene3D G3DSA:2.40.50.250 482 576 8.5E-41 T 06-07-2017 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 145 1.1E-25 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 PRINTS PR00315 GTP-binding elongation factor signature 69 79 4.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 PRINTS PR00315 GTP-binding elongation factor signature 85 96 4.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 PRINTS PR00315 GTP-binding elongation factor signature 121 130 4.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 PRINTS PR00315 GTP-binding elongation factor signature 5 18 4.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Gene3D G3DSA:3.40.50.300 2 202 1.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 SUPERFAMILY SSF52540 3 199 8.07E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Pfam PF00679 Elongation factor G C-terminus 396 480 2.6E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS08715 8dc97ff4906e95c0cc42eab495d883f6 608 Pfam PF03144 Elongation factor Tu domain 2 217 288 9.3E-13 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Gene3D G3DSA:1.10.1040.10 510 606 4.2E-17 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Gene3D G3DSA:1.10.1040.10 645 723 3.4E-14 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 213 7.8E-33 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Gene3D G3DSA:3.40.50.720 321 509 5.0E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 508 605 4.7E-21 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 SUPERFAMILY SSF51735 325 506 2.81E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 SUPERFAMILY SSF52096 4 318 5.81E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 SUPERFAMILY SSF48179 507 627 9.35E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 328 505 1.4E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 Gene3D G3DSA:3.90.226.10 2 215 2.8E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS05585 72dd7ed0453dfd820f1545024fd55066 735 SUPERFAMILY SSF48179 634 723 1.19E-20 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 Pfam PF01678 Diaminopimelate epimerase 9 127 1.6E-15 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 Pfam PF01678 Diaminopimelate epimerase 161 274 7.0E-26 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 69 83 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 SUPERFAMILY SSF54506 148 281 7.46E-49 T 06-07-2017 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 SUPERFAMILY SSF54506 9 134 1.96E-34 T 06-07-2017 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 Gene3D G3DSA:3.10.310.10 6 122 7.2E-36 T 06-07-2017 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 8 280 1.6E-65 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 7 283 32.241 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK95_RS07620 7943f3027d15d9019482bac68c94a8ac 292 Gene3D G3DSA:3.10.310.10 123 271 3.6E-50 T 06-07-2017 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 SUPERFAMILY SSF64288 70 246 3.93E-35 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 SUPERFAMILY SSF46785 14 86 4.55E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 SMART SM00345 23 82 3.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 SMART SM00866 102 242 2.1E-22 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 Gene3D G3DSA:3.40.1410.10 80 246 5.3E-40 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 5.5E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 5.5E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 Gene3D G3DSA:1.10.10.10 14 79 4.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 Pfam PF07702 UTRA domain 107 238 1.8E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS00830 acd0630ca24bb07853d6a4856551ef0c 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 4.4E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 Pfam PF00072 Response regulator receiver domain 18 124 1.4E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 SUPERFAMILY SSF46894 143 234 2.83E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 SMART SM00862 161 233 2.5E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 Gene3D G3DSA:3.40.50.2300 13 134 1.2E-38 T 06-07-2017 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 SUPERFAMILY SSF52172 12 138 1.12E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 Gene3D G3DSA:1.10.10.10 140 234 5.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 SMART SM00448 15 125 2.3E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS01660 12c08221dcdbdeb81f8894c275d97d8c 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 233 7.9E-16 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS23365 4fc93c92bc6020c5f07fec349a7de912 417 Pfam PF05065 Phage capsid family 143 317 4.4E-13 T 06-07-2017 IPR024455 Phage capsid CAK95_RS23365 4fc93c92bc6020c5f07fec349a7de912 417 SUPERFAMILY SSF56563 141 397 1.16E-13 T 06-07-2017 CAK95_RS23365 4fc93c92bc6020c5f07fec349a7de912 417 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 32 296 3.6E-14 T 06-07-2017 IPR006444 Phage major capsid protein, HK97 CAK95_RS02245 fbab2600b0fb44ab25c39c52c0f15c07 184 SMART SM00347 57 157 1.4E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02245 fbab2600b0fb44ab25c39c52c0f15c07 184 Gene3D G3DSA:1.10.10.10 21 172 1.6E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02245 fbab2600b0fb44ab25c39c52c0f15c07 184 Pfam PF01047 MarR family 70 121 8.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02245 fbab2600b0fb44ab25c39c52c0f15c07 184 SUPERFAMILY SSF46785 28 171 1.08E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 Gene3D G3DSA:3.30.70.1300 60 150 8.7E-25 T 06-07-2017 CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 Gene3D G3DSA:3.40.1740.10 151 195 7.3E-31 T 06-07-2017 CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 Gene3D G3DSA:3.40.1740.10 16 56 7.3E-31 T 06-07-2017 CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 Pfam PF02622 Uncharacterized ACR, COG1678 28 193 9.5E-46 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 SUPERFAMILY SSF143456 18 206 8.76E-58 T 06-07-2017 CAK95_RS04250 b7326c1b045dc1ab5a5f673295705a0a 206 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 17 206 34.618 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 SUPERFAMILY SSF52518 381 575 2.95E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Gene3D G3DSA:3.40.50.1220 179 332 6.4E-51 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 324 7.2E-34 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Gene3D G3DSA:3.40.50.970 350 565 2.3E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 2 577 2.6E-293 T 06-07-2017 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 SUPERFAMILY SSF52518 2 179 2.54E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 556 7.7E-30 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Gene3D G3DSA:3.40.50.970 2 176 4.6E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 SUPERFAMILY SSF52467 153 356 1.35E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS09385 b722c2bf1071f5d0ebc806625c9df61f 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 8.0E-40 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 393 417 - T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 Pfam PF01019 Gamma-glutamyltranspeptidase 64 575 3.0E-180 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 572 3.0E-182 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 165 184 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 280 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 294 313 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 71 96 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 145 163 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 458 473 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 482 499 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 393 411 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 417 435 1.9E-79 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS08505 5a92c41fccb761c750e1796a00add169 581 SUPERFAMILY SSF56235 41 578 4.82E-185 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS07025 b312d18e5dea6e0636c8e488a7abc508 599 Pfam PF00999 Sodium/hydrogen exchanger family 11 387 3.1E-76 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK95_RS07025 b312d18e5dea6e0636c8e488a7abc508 599 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 16 297 1.4E-71 T 06-07-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CAK95_RS07025 b312d18e5dea6e0636c8e488a7abc508 599 Pfam PF02254 TrkA-N domain 426 540 4.6E-22 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK95_RS07025 b312d18e5dea6e0636c8e488a7abc508 599 SUPERFAMILY SSF51735 424 550 5.69E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07025 b312d18e5dea6e0636c8e488a7abc508 599 Gene3D G3DSA:3.40.50.720 422 552 3.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26380 f98d62fe2d7b68e58515e336c94b31d1 312 TIGRFAM TIGR03814 Gln_ase: glutaminase A 12 310 9.7E-127 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS26380 f98d62fe2d7b68e58515e336c94b31d1 312 Pfam PF04960 Glutaminase 25 310 4.2E-112 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS26380 f98d62fe2d7b68e58515e336c94b31d1 312 Gene3D G3DSA:3.40.710.10 5 310 8.2E-120 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS26380 f98d62fe2d7b68e58515e336c94b31d1 312 SUPERFAMILY SSF56601 6 310 9.72E-112 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS26380 f98d62fe2d7b68e58515e336c94b31d1 312 Hamap MF_00313 Glutaminase [glsA]. 7 310 45.779 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 285 6.6E-66 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 5.2E-41 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 Gene3D G3DSA:3.40.50.720 139 268 1.1E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 SUPERFAMILY SSF51735 123 284 4.95E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 243 259 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 260 278 1.4E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 287 38.403 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 Gene3D G3DSA:3.40.192.10 7 138 1.4E-50 T 06-07-2017 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 264 272 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS08680 5c3d019abcc3a52f017300930c4780ae 294 SUPERFAMILY SSF53223 1 122 3.55E-41 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Gene3D G3DSA:3.10.150.10 1 121 6.4E-31 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Gene3D G3DSA:3.10.150.10 255 372 3.2E-38 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Gene3D G3DSA:3.10.150.10 126 254 8.0E-39 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 PIRSF PIRSF000804 1 372 4.1E-125 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 7.8E-36 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 371 8.9E-98 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 249 2.5E-35 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 SUPERFAMILY SSF55979 1 119 1.19E-26 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 371 3.7E-31 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 SUPERFAMILY SSF55979 127 250 2.23E-29 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 SUPERFAMILY SSF55979 253 372 2.72E-37 T 06-07-2017 CAK95_RS09450 e1db3ea16f03696a69c3a96a55201343 372 SMART SM00480 17 368 2.0E-132 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS23005 3c8e5a9bc31262976f090ddec2f43d41 153 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 11 152 31.025 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS23005 3c8e5a9bc31262976f090ddec2f43d41 153 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 12 149 5.2E-54 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS23005 3c8e5a9bc31262976f090ddec2f43d41 153 SUPERFAMILY SSF54637 11 150 3.74E-45 T 06-07-2017 IPR029069 HotDog domain CAK95_RS23005 3c8e5a9bc31262976f090ddec2f43d41 153 Pfam PF07977 FabA-like domain 20 145 6.0E-36 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS23005 3c8e5a9bc31262976f090ddec2f43d41 153 Gene3D G3DSA:3.10.129.10 9 151 1.9E-52 T 06-07-2017 IPR029069 HotDog domain CAK95_RS05980 cdbbe93d77bc02128a60400455156f9a 535 Gene3D G3DSA:3.50.50.60 3 123 3.5E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05980 cdbbe93d77bc02128a60400455156f9a 535 Gene3D G3DSA:3.50.50.60 224 306 3.5E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05980 cdbbe93d77bc02128a60400455156f9a 535 SUPERFAMILY SSF51905 8 327 2.82E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05980 cdbbe93d77bc02128a60400455156f9a 535 SUPERFAMILY SSF51905 473 516 2.82E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05980 cdbbe93d77bc02128a60400455156f9a 535 Pfam PF01593 Flavin containing amine oxidoreductase 16 313 1.2E-7 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 Gene3D G3DSA:3.40.50.1980 216 364 4.0E-57 T 06-07-2017 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 SUPERFAMILY SSF53720 20 420 1.71E-68 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 Pfam PF00815 Histidinol dehydrogenase 17 420 4.6E-140 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 Gene3D G3DSA:3.40.50.1980 19 215 1.8E-70 T 06-07-2017 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 9 420 32.873 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 25 49 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PRINTS PR00083 Histidinol dehydrogenase signature 100 127 5.0E-68 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 25 419 5.2E-138 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS16190 548d80cacc476d0a03c3849245163d25 435 PIRSF PIRSF000099 3 423 1.5E-121 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS19785 1937aeaedf863210f5ff48601007e1ed 275 Pfam PF01925 Sulfite exporter TauE/SafE 17 269 2.9E-43 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 249 272 4.8E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 576 589 4.8E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 441 456 4.8E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 55 66 4.8E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 6 984 19.617 T 06-07-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Pfam PF08264 Anticodon-binding domain of tRNA 745 894 5.0E-20 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 62 73 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Gene3D G3DSA:3.40.50.620 446 696 2.5E-130 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Gene3D G3DSA:3.40.50.620 17 212 2.5E-130 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 700 5.2E-180 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 SUPERFAMILY SSF52374 8 214 3.18E-126 T 06-07-2017 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 SUPERFAMILY SSF52374 443 709 3.18E-126 T 06-07-2017 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 SUPERFAMILY SSF47323 712 984 1.02E-56 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 SUPERFAMILY SSF50677 216 443 1.88E-40 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Gene3D G3DSA:3.90.740.10 218 429 8.7E-45 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 Gene3D G3DSA:1.10.730.10 703 881 2.3E-34 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS13305 b0f132b25e2b1a18354459b00fec2195 994 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 19 896 2.1E-234 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 Pfam PF08359 YsiA-like protein, C-terminal region 120 224 3.0E-6 T 06-07-2017 IPR013570 Transcription regulator YsiA, C-terminal CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 SUPERFAMILY SSF48498 137 248 1.18E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 SUPERFAMILY SSF46689 56 134 1.08E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 Gene3D G3DSA:1.10.10.60 60 112 1.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 Gene3D G3DSA:1.10.357.10 113 250 4.5E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 67 80 3.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 88 111 3.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS03325 f84b11950e74ed1a80b032518f2556fe 286 Pfam PF00440 Bacterial regulatory proteins, tetR family 67 111 2.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 325 63.345 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 186 2.9E-31 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 325 2.9E-108 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 SUPERFAMILY SSF53901 8 325 6.25E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 Gene3D G3DSA:3.40.47.10 163 325 1.4E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 Gene3D G3DSA:3.40.47.10 4 162 8.8E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS23025 becfd8d2f5bf7c803fabeea4fc332edc 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 325 1.3E-31 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 Gene3D G3DSA:1.25.50.10 553 878 2.9E-120 T 06-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 Pfam PF01433 Peptidase family M1 22 389 2.7E-66 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 Pfam PF11940 Domain of unknown function (DUF3458) 464 835 5.9E-136 T 06-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 SUPERFAMILY SSF55486 209 453 5.37E-73 T 06-07-2017 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 2.4E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 263 273 2.4E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 2.4E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 2.4E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 SUPERFAMILY SSF63737 5 197 3.01E-45 T 06-07-2017 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 877 0.0 T 06-07-2017 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 CAK95_RS19205 8d8036bcc3bbaaa699e992907d9bdaae 880 Gene3D G3DSA:1.10.390.10 313 453 2.5E-30 T 06-07-2017 CAK95_RS19385 1fae6952c8ad683505efb70c96412188 762 SUPERFAMILY SSF69572 379 489 4.32E-6 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS19385 1fae6952c8ad683505efb70c96412188 762 Pfam PF14464 Prokaryotic homologs of the JAB domain 634 748 8.8E-13 T 06-07-2017 IPR028090 JAB domain, prokaryotic CAK95_RS19385 1fae6952c8ad683505efb70c96412188 762 Gene3D G3DSA:3.40.50.720 379 438 9.7E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS19385 1fae6952c8ad683505efb70c96412188 762 Pfam PF14457 Prokaryotic E2 family A 15 179 1.7E-54 T 06-07-2017 IPR032865 Prokaryotic E2 family A CAK95_RS19385 1fae6952c8ad683505efb70c96412188 762 Pfam PF00899 ThiF family 379 438 3.6E-6 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS02995 2b13c4f2d661ebae8dcac238cb2048e5 209 Pfam PF04542 Sigma-70 region 2 41 91 6.9E-6 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02995 2b13c4f2d661ebae8dcac238cb2048e5 209 Gene3D G3DSA:1.10.1740.10 25 91 6.1E-5 T 06-07-2017 CAK95_RS02995 2b13c4f2d661ebae8dcac238cb2048e5 209 SUPERFAMILY SSF88946 25 92 1.57E-7 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 SUPERFAMILY SSF46689 38 117 5.13E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 Gene3D G3DSA:1.10.10.60 38 85 1.7E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 Gene3D G3DSA:1.10.357.10 101 228 2.9E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 SUPERFAMILY SSF48498 115 239 2.54E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 Gene3D G3DSA:1.10.10.60 86 100 2.8E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 94 1.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 2.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS25265 a1abba47c39a6573c4c4e08ac39f42c1 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 2.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 2.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 2.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 Gene3D G3DSA:1.10.10.10 23 166 2.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 Pfam PF13463 Winged helix DNA-binding domain 56 120 2.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 SUPERFAMILY SSF46785 23 163 6.55E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22420 bedb19fd50ffc48b09d886a11a0cadac 171 SMART SM00347 48 149 1.3E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS21120 105e6d9888ce5c4423aba20b68cc40db 124 Pfam PF00034 Cytochrome c 41 118 4.0E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS21120 105e6d9888ce5c4423aba20b68cc40db 124 Gene3D G3DSA:1.10.760.10 25 119 1.0E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS21120 105e6d9888ce5c4423aba20b68cc40db 124 SUPERFAMILY SSF46626 21 120 6.68E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 SUPERFAMILY SSF52402 1 131 4.94E-29 T 06-07-2017 CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 Gene3D G3DSA:3.40.50.620 129 283 3.7E-33 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 Pfam PF00582 Universal stress protein family 1 130 1.6E-24 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 Pfam PF00582 Universal stress protein family 139 282 1.7E-23 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 Gene3D G3DSA:3.40.50.620 1 128 4.0E-30 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 SUPERFAMILY SSF52402 139 282 3.68E-29 T 06-07-2017 CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 PRINTS PR01438 Universal stress protein signature 260 282 3.5E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 PRINTS PR01438 Universal stress protein signature 1 18 3.5E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS06485 b4e2b6ef216d880ecf150fae0542674c 294 PRINTS PR01438 Universal stress protein signature 242 254 3.5E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS09795 b328ef523be0f8626537c7163d5d9a3e 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 135 1.0E-9 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS09795 b328ef523be0f8626537c7163d5d9a3e 383 Gene3D G3DSA:3.30.360.10 159 374 1.4E-36 T 06-07-2017 CAK95_RS09795 b328ef523be0f8626537c7163d5d9a3e 383 SUPERFAMILY SSF55347 146 330 1.8E-28 T 06-07-2017 CAK95_RS09795 b328ef523be0f8626537c7163d5d9a3e 383 Gene3D G3DSA:3.40.50.720 7 158 4.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09795 b328ef523be0f8626537c7163d5d9a3e 383 SUPERFAMILY SSF51735 50 173 1.01E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 SUPERFAMILY SSF52172 4 130 1.85E-44 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 SUPERFAMILY SSF46894 136 232 1.87E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 SMART SM00862 155 231 2.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 Gene3D G3DSA:3.40.50.2300 5 131 2.3E-44 T 06-07-2017 CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 Pfam PF00072 Response regulator receiver domain 7 116 1.1E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 Gene3D G3DSA:1.10.10.10 134 233 6.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 SMART SM00448 5 115 1.0E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS03570 45453ab83855ecc29913af7e990d598b 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 3.3E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS10830 88769d521a51ec2e32b8a90f37eca184 409 Gene3D G3DSA:3.40.50.2000 223 375 8.4E-24 T 06-07-2017 CAK95_RS10830 88769d521a51ec2e32b8a90f37eca184 409 SUPERFAMILY SSF53756 8 398 4.71E-77 T 06-07-2017 CAK95_RS10830 88769d521a51ec2e32b8a90f37eca184 409 Pfam PF00534 Glycosyl transferases group 1 223 375 1.3E-29 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS10830 88769d521a51ec2e32b8a90f37eca184 409 Pfam PF13439 Glycosyltransferase Family 4 14 220 8.8E-20 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 Gene3D G3DSA:1.10.101.10 433 487 2.2E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 Gene3D G3DSA:1.10.530.10 167 220 6.5E-54 T 06-07-2017 CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 Gene3D G3DSA:1.10.530.10 301 417 6.5E-54 T 06-07-2017 CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 SUPERFAMILY SSF47090 420 488 2.62E-8 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 Pfam PF13406 Transglycosylase SLT domain 119 412 1.7E-103 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 SUPERFAMILY SSF53955 108 417 7.5E-95 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 119 415 2.8E-104 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS15995 cfaab6ac0c84ddf1c042465d961e0d0e 491 Pfam PF01471 Putative peptidoglycan binding domain 433 484 5.7E-6 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS17895 0f0b95e2ea19470cd6310f96bc3d33da 397 Gene3D G3DSA:1.20.1250.20 5 186 9.7E-29 T 06-07-2017 CAK95_RS17895 0f0b95e2ea19470cd6310f96bc3d33da 397 Gene3D G3DSA:1.20.1250.20 201 380 8.9E-12 T 06-07-2017 CAK95_RS17895 0f0b95e2ea19470cd6310f96bc3d33da 397 Pfam PF07690 Major Facilitator Superfamily 9 325 7.2E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS17895 0f0b95e2ea19470cd6310f96bc3d33da 397 SUPERFAMILY SSF103473 3 381 2.62E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS18420 a8b2c0ca9ff2d8e49e076237235eff3e 181 SUPERFAMILY SSF82199 16 128 1.83E-32 T 06-07-2017 CAK95_RS18420 a8b2c0ca9ff2d8e49e076237235eff3e 181 Gene3D G3DSA:2.170.270.10 15 128 9.2E-30 T 06-07-2017 CAK95_RS18420 a8b2c0ca9ff2d8e49e076237235eff3e 181 SMART SM00317 7 116 2.5E-25 T 06-07-2017 IPR001214 SET domain GO:0005515 CAK95_RS18420 a8b2c0ca9ff2d8e49e076237235eff3e 181 Pfam PF00856 SET domain 17 110 1.7E-15 T 06-07-2017 IPR001214 SET domain GO:0005515 CAK95_RS21085 f86220c72ca971db083098b9b2bc07f1 123 Gene3D G3DSA:3.40.50.2300 17 122 1.2E-14 T 06-07-2017 CAK95_RS21085 f86220c72ca971db083098b9b2bc07f1 123 SUPERFAMILY SSF52172 14 123 6.12E-13 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS21085 f86220c72ca971db083098b9b2bc07f1 123 Pfam PF00072 Response regulator receiver domain 17 120 1.6E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 SMART SM00245 191 393 1.1E-6 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 SMART SM00228 137 202 2.5E-6 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 SUPERFAMILY SSF52096 41 112 3.31E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 SUPERFAMILY SSF52096 215 417 3.31E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 Pfam PF13180 PDZ domain 137 210 1.2E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 Pfam PF03572 Peptidase family S41 239 392 2.4E-20 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 SUPERFAMILY SSF50156 131 208 3.94E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 Gene3D G3DSA:2.30.42.10 137 209 6.8E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 Gene3D G3DSA:3.30.750.44 41 136 1.2E-4 T 06-07-2017 CAK95_RS10255 97c85b6a1039aa23ae873b8d9e8f486f 419 Gene3D G3DSA:3.90.226.10 226 416 4.0E-30 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 Gene3D G3DSA:2.30.140.10 4 58 4.3E-18 T 06-07-2017 CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 Pfam PF01564 Spermine/spermidine synthase 16 241 1.3E-70 T 06-07-2017 CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 83 96 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 Gene3D G3DSA:3.40.50.150 59 286 5.1E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 TIGRFAM TIGR00417 speE: spermidine synthase 14 281 5.0E-92 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 287 36.735 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CAK95_RS25670 417ed7921a5c29951ef69670b41f2614 289 SUPERFAMILY SSF53335 6 286 5.45E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:1.20.120.160 4 139 3.3E-31 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:2.30.30.40 657 701 1.5E-19 T 06-07-2017 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:2.30.30.40 570 591 1.5E-19 T 06-07-2017 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SUPERFAMILY SSF47384 323 385 9.42E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SUPERFAMILY SSF47226 4 128 4.06E-27 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Pfam PF01627 Hpt domain 8 91 1.0E-15 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:2.40.50.180 593 656 5.5E-10 T 06-07-2017 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SMART SM01231 321 384 4.8E-12 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Pfam PF01584 CheW-like domain 575 702 5.6E-27 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SUPERFAMILY SSF55874 390 568 1.83E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:1.10.287.560 322 385 1.7E-13 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Gene3D G3DSA:3.30.565.10 389 569 1.2E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SMART SM00387 429 570 1.3E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SUPERFAMILY SSF50341 569 701 1.31E-29 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 548 6.1E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 6.1E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 6.1E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SMART SM00073 3 101 1.1E-27 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 323 384 5.3E-11 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 SMART SM00260 562 702 3.7E-36 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS06045 d5257b8e2a2a36df6e666eccc7ae8e54 725 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 431 569 3.7E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 Pfam PF03308 ArgK protein 23 295 1.0E-112 T 06-07-2017 CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 Gene3D G3DSA:3.40.50.300 56 261 6.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 SUPERFAMILY SSF52540 7 324 3.01E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 Gene3D G3DSA:1.20.5.170 9 55 1.2E-20 T 06-07-2017 CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 Gene3D G3DSA:1.10.287.130 264 323 5.8E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18705 2c442c95dbbc3c06552f30a2fff8f866 328 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 18 323 2.8E-111 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 SUPERFAMILY SSF54665 2 142 3.4E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 455 588 1.8E-40 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 280 355 7.8E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 121 170 7.8E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 613 761 2.4E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 358 454 2.4E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 SMART SM01008 18 132 9.0E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 158 698 5.0E-153 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 132 2.7E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 SUPERFAMILY SSF56003 124 761 6.02E-166 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.30.365.10 171 277 2.8E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27775 65f31377022c7278d1df54fa55b8ae29 768 Gene3D G3DSA:3.90.1170.50 2 120 5.0E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS02885 242f13e04689bc9f52de8cc7dfaa137c 255 Gene3D G3DSA:3.40.50.300 3 230 1.0E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02885 242f13e04689bc9f52de8cc7dfaa137c 255 SUPERFAMILY SSF52540 3 227 3.49E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02885 242f13e04689bc9f52de8cc7dfaa137c 255 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS02885 242f13e04689bc9f52de8cc7dfaa137c 255 SMART SM00382 27 215 1.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02885 242f13e04689bc9f52de8cc7dfaa137c 255 Pfam PF00005 ABC transporter 21 167 2.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS01120 ae0f091377deb8b52ee2bcd9c4df0060 214 SUPERFAMILY SSF51182 109 179 4.45E-5 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 Gene3D G3DSA:3.50.7.10 189 366 1.5E-101 T 06-07-2017 IPR027409 GroEL-like apical domain CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 SUPERFAMILY SSF54849 138 205 1.65E-23 T 06-07-2017 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 PRINTS PR00298 60kDa chaperonin signature 268 291 2.9E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 PRINTS PR00298 60kDa chaperonin signature 83 110 2.9E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 PRINTS PR00298 60kDa chaperonin signature 398 419 2.9E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 PRINTS PR00298 60kDa chaperonin signature 350 375 2.9E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 PRINTS PR00298 60kDa chaperonin signature 27 53 2.9E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 SUPERFAMILY SSF52029 184 376 1.2E-85 T 06-07-2017 IPR027409 GroEL-like apical domain CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 1.8E-262 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 Gene3D G3DSA:1.10.560.10 3 188 3.1E-46 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 3.2E-100 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 SUPERFAMILY SSF48592 406 522 4.43E-79 T 06-07-2017 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 SUPERFAMILY SSF48592 7 134 4.43E-79 T 06-07-2017 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 42.214 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK95_RS20555 bb1fab67a7700b7a772212541be82f98 547 Gene3D G3DSA:1.10.560.10 367 519 2.0E-44 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 310 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 325 344 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 149 163 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 179 198 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 217 236 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 270 286 5.0E-59 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 PIRSF PIRSF001415 26 354 2.5E-150 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 Gene3D G3DSA:3.20.20.70 29 352 2.7E-150 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 SUPERFAMILY SSF51569 28 352 2.93E-144 T 06-07-2017 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 270 282 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 SMART SM01004 29 351 2.1E-240 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS22395 60cb81546059c2d004baea1c431f28a8 354 Pfam PF00490 Delta-aminolevulinic acid dehydratase 32 349 9.8E-144 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 Gene3D G3DSA:3.30.70.260 281 324 4.8E-4 T 06-07-2017 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 SUPERFAMILY SSF55021 343 415 2.62E-20 T 06-07-2017 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 Gene3D G3DSA:3.40.1160.10 1 257 2.4E-71 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 412 8.4E-110 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 4 412 8.3E-124 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 Pfam PF00696 Amino acid kinase family 3 231 2.2E-44 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 SUPERFAMILY SSF53633 3 254 8.64E-68 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 Pfam PF13840 ACT domain 350 410 1.1E-11 T 06-07-2017 IPR027795 GATS-like ACT domain CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 SUPERFAMILY SSF55021 258 337 4.37E-18 T 06-07-2017 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 Pfam PF01842 ACT domain 276 333 1.9E-10 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS10400 bd3fd6ab393f3353daa770b7256830e9 417 PIRSF PIRSF000726 60 417 5.2E-124 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS04735 1dde4b37d193ed3f4dd80670d7970246 182 Pfam PF06041 Bacterial protein of unknown function (DUF924) 11 179 4.5E-62 T 06-07-2017 IPR010323 Protein of unknown function DUF924 CAK95_RS04735 1dde4b37d193ed3f4dd80670d7970246 182 Gene3D G3DSA:1.25.40.10 82 181 1.5E-37 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS04735 1dde4b37d193ed3f4dd80670d7970246 182 Gene3D G3DSA:1.20.58.320 7 80 3.7E-31 T 06-07-2017 CAK95_RS04735 1dde4b37d193ed3f4dd80670d7970246 182 SUPERFAMILY SSF48452 7 178 1.48E-64 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 37 530 8.0E-204 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 SUPERFAMILY SSF81452 587 820 2.88E-6 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 265 319 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 45 492 3.3E-134 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 SUPERFAMILY SSF81442 34 540 1.96E-148 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 Gene3D G3DSA:1.20.210.10 34 557 1.2E-157 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 Gene3D G3DSA:1.20.120.80 661 821 2.4E-6 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 109 133 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 35 60 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 263 284 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 163 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 370 388 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 398 417 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 448 469 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 82 105 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 309 324 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11610 36345cc5f25626968639365c5201c2a2 845 PRINTS PR01165 Cytochrome c oxidase subunit I signature 333 354 1.2E-83 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 Gene3D G3DSA:3.30.450.40 88 266 3.2E-43 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 Pfam PF01614 Bacterial transcriptional regulator 138 261 5.2E-23 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 SMART SM00346 18 108 6.6E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 SUPERFAMILY SSF46785 18 90 1.15E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 Pfam PF09339 IclR helix-turn-helix domain 21 70 4.4E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 Gene3D G3DSA:1.10.10.10 15 87 2.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17100 a27cacb3a5122bfcd43b5c1c4a59378e 267 SUPERFAMILY SSF55781 85 266 1.18E-38 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Gene3D G3DSA:1.10.540.10 21 111 3.0E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 110 3.8E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 166 250 2.1E-11 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 278 394 1.0E-11 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Gene3D G3DSA:1.20.140.10 252 415 1.1E-24 T 06-07-2017 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 SUPERFAMILY SSF47203 267 412 1.11E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 Gene3D G3DSA:2.40.110.10 162 251 3.9E-23 T 06-07-2017 CAK95_RS27065 73445304b19f93c46f333278e632971e 423 SUPERFAMILY SSF56645 21 260 1.16E-43 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PIRSF PIRSF002133 1 123 1.7E-53 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 5.0E-60 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 Gene3D G3DSA:2.40.50.140 1 123 1.1E-64 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.539 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 Pfam PF00164 Ribosomal protein S12/S23 5 123 2.3E-41 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 SUPERFAMILY SSF50249 2 123 8.57E-52 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21240 3ad710da76bdb5598438c0d0a5e780d3 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 4.8E-67 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS04415 caa4475f1eb09faf3d8980e15e0c7946 412 Pfam PF00326 Prolyl oligopeptidase family 231 395 1.3E-10 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK95_RS04415 caa4475f1eb09faf3d8980e15e0c7946 412 Gene3D G3DSA:1.20.1440.110 37 145 2.6E-24 T 06-07-2017 CAK95_RS04415 caa4475f1eb09faf3d8980e15e0c7946 412 SUPERFAMILY SSF53474 37 399 1.51E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS04415 caa4475f1eb09faf3d8980e15e0c7946 412 Gene3D G3DSA:3.40.50.1820 148 397 1.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Gene3D G3DSA:3.30.1600.10 128 175 8.9E-18 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Gene3D G3DSA:3.30.1600.10 39 74 8.9E-18 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Pfam PF02146 Sir2 family 28 206 1.5E-42 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Gene3D G3DSA:3.40.50.1220 88 127 1.7E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Gene3D G3DSA:3.40.50.1220 182 251 1.7E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 Gene3D G3DSA:3.40.50.1220 10 38 1.7E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS24655 5f7eaa015107d1b23259745eb4315a46 253 SUPERFAMILY SSF52467 8 252 6.55E-77 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:2.70.20.10 323 460 2.7E-39 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:2.70.20.10 188 319 2.1E-31 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:3.40.50.140 1 135 1.2E-43 T 06-07-2017 IPR006171 Toprim domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SMART SM00493 1 101 1.2E-29 T 06-07-2017 IPR006171 Toprim domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SMART SM00437 248 521 3.3E-112 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:1.10.460.10 461 573 8.9E-56 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:1.10.460.10 136 187 8.9E-56 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Gene3D G3DSA:3.30.65.10 604 638 9.2E-11 T 06-07-2017 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 285 307 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SMART SM00436 106 194 1.6E-44 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 603 640 9.7E-15 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF01751 Toprim domain 3 115 1.5E-26 T 06-07-2017 IPR006171 Toprim domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 298 307 3.6E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 376 392 3.6E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 75 88 3.6E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 164 182 3.6E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 484 498 3.6E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 728 53.44 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SUPERFAMILY SSF56712 603 612 1.57E-184 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SUPERFAMILY SSF56712 1 572 1.57E-184 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF13368 Topoisomerase C-terminal repeat 716 769 8.9E-19 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF13368 Topoisomerase C-terminal repeat 785 838 6.2E-18 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF13368 Topoisomerase C-terminal repeat 655 713 4.0E-15 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 3 638 2.1E-235 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 Pfam PF01131 DNA topoisomerase 130 558 3.0E-125 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CAK95_RS22065 8900f6c4a7f46c2aa91ffdd0ae83a569 917 SUPERFAMILY SSF57783 602 638 9.52E-9 T 06-07-2017 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 SUPERFAMILY SSF51338 359 398 5.92E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 SUPERFAMILY SSF51338 2 52 5.92E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 Gene3D G3DSA:2.30.40.10 3 57 9.5E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 Gene3D G3DSA:3.20.20.140 58 341 2.7E-99 T 06-07-2017 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 Gene3D G3DSA:2.30.40.10 342 400 2.4E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 53 61 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 Pfam PF07969 Amidohydrolase family 43 128 7.5E-8 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 Pfam PF07969 Amidohydrolase family 155 397 1.3E-23 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS27635 f861797f445c8e506f3d8bd157e0aada 420 SUPERFAMILY SSF51556 52 368 5.0E-84 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 16 147 1.3E-47 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 16 390 8.0E-137 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 SMART SM01097 14 148 1.6E-80 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00096 Glutamine amidotransferase superfamily signature 279 290 9.8E-12 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00096 Glutamine amidotransferase superfamily signature 364 377 9.8E-12 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00096 Glutamine amidotransferase superfamily signature 250 259 9.8E-12 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 Gene3D G3DSA:3.40.50.880 171 393 1.6E-79 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 SUPERFAMILY SSF52021 15 164 9.94E-52 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 Pfam PF00117 Glutamine amidotransferase class-I 210 387 1.4E-48 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 247 261 2.6E-36 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 295 2.6E-36 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 208 222 2.6E-36 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 321 332 2.6E-36 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 296 313 2.6E-36 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00097 Anthranilate synthase component II signature 250 259 4.5E-6 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00097 Anthranilate synthase component II signature 364 377 4.5E-6 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 PRINTS PR00097 Anthranilate synthase component II signature 279 290 4.5E-6 T 06-07-2017 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 SUPERFAMILY SSF52317 184 393 3.21E-63 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 14 393 47.732 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13835 4d13be867b3173313b5cc325bcdad930 397 Gene3D G3DSA:3.50.30.20 15 163 1.0E-54 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS28755 acd55c2ec497c7f63aa763d7c1a099c7 280 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28755 acd55c2ec497c7f63aa763d7c1a099c7 280 SUPERFAMILY SSF52540 27 256 1.42E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28755 acd55c2ec497c7f63aa763d7c1a099c7 280 SMART SM00382 56 237 2.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28755 acd55c2ec497c7f63aa763d7c1a099c7 280 Pfam PF00005 ABC transporter 49 186 4.5E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28755 acd55c2ec497c7f63aa763d7c1a099c7 280 Gene3D G3DSA:3.40.50.300 24 245 5.5E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 Gene3D G3DSA:3.90.25.10 172 215 4.9E-42 T 06-07-2017 CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 Gene3D G3DSA:3.90.25.10 255 323 4.9E-42 T 06-07-2017 CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 SUPERFAMILY SSF51735 1 323 2.39E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 1.4E-51 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 325 3.7E-133 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 Gene3D G3DSA:3.40.50.720 1 171 3.8E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17545 7bfc65533599ce0e1b71550c528f7fdd 328 Gene3D G3DSA:3.40.50.720 216 254 3.8E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.4E-20 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.4E-20 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-20 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 1.4E-20 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.4E-20 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 SUPERFAMILY SSF51905 2 168 6.6E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 SUPERFAMILY SSF51905 266 371 6.6E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 SUPERFAMILY SSF54373 172 272 7.85E-16 T 06-07-2017 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 Pfam PF01494 FAD binding domain 3 339 5.8E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 Gene3D G3DSA:3.50.50.60 266 347 9.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12380 2146dadc39226ef11828add3729c7ad7 404 Gene3D G3DSA:3.50.50.60 2 174 9.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00265 885a626e84e06b3147f9a40f4d8b8cbf 467 Pfam PF00171 Aldehyde dehydrogenase family 2 454 2.6E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS00265 885a626e84e06b3147f9a40f4d8b8cbf 467 SUPERFAMILY SSF53720 3 459 1.44E-151 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS00265 885a626e84e06b3147f9a40f4d8b8cbf 467 Gene3D G3DSA:3.40.309.10 246 429 6.4E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS00265 885a626e84e06b3147f9a40f4d8b8cbf 467 Gene3D G3DSA:3.40.605.10 2 245 1.8E-78 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 SUPERFAMILY SSF69287 1 70 4.84E-12 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 PIRSF PIRSF036402 2 161 8.5E-40 T 06-07-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 SMART SM00988 3 68 7.0E-16 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 142 21.405 T 06-07-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 Gene3D G3DSA:2.60.260.20 17 70 7.5E-11 T 06-07-2017 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 SUPERFAMILY SSF69737 74 138 7.06E-20 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 Pfam PF02814 UreE urease accessory protein, N-terminal domain 16 68 1.1E-13 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 Pfam PF05194 UreE urease accessory protein, C-terminal domain 75 162 1.1E-25 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS17345 93d04d994cf2f6378345a19c1428531a 165 Gene3D G3DSA:3.30.70.790 75 142 5.9E-26 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 Gene3D G3DSA:3.30.70.260 325 389 4.0E-7 T 06-07-2017 CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 301 2.0E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 Gene3D G3DSA:3.40.50.1100 69 317 3.4E-69 T 06-07-2017 CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 395 1.4E-123 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 SUPERFAMILY SSF53686 4 309 1.28E-89 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS22390 af2b7551d0141450ee9b5202473def79 406 SUPERFAMILY SSF55021 326 389 2.01E-6 T 06-07-2017 CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 Pfam PF02706 Chain length determinant protein 32 201 4.5E-17 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 580 749 2.0E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 566 751 5.5E-35 T 06-07-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 SUPERFAMILY SSF52540 569 754 1.4E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 Gene3D G3DSA:3.40.50.300 567 754 1.2E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27505 35a9d470106b94651b571510d447dff7 771 Pfam PF13807 G-rich domain on putative tyrosine kinase 400 472 6.8E-9 T 06-07-2017 IPR032807 Tyrosine kinase, G-rich domain CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 SUPERFAMILY SSF55816 311 508 3.66E-56 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 SUPERFAMILY SSF56300 33 307 1.74E-56 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 Pfam PF00149 Calcineurin-like phosphoesterase 35 237 6.1E-7 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 Pfam PF02872 5'-nucleotidase, C-terminal domain 314 470 4.3E-47 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 PRINTS PR01607 Apyrase family signature 444 463 3.9E-13 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 PRINTS PR01607 Apyrase family signature 202 219 3.9E-13 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 PRINTS PR01607 Apyrase family signature 371 394 3.9E-13 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 Gene3D G3DSA:3.60.21.10 28 308 1.1E-58 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS16405 87bf20f57565e4c6a685c9e8f08171e9 509 Gene3D G3DSA:3.90.780.10 314 508 1.1E-53 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS21115 e7308cfcb8f923061dafce3f12cbdd66 306 SUPERFAMILY SSF117892 50 186 3.27E-11 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS21115 e7308cfcb8f923061dafce3f12cbdd66 306 Pfam PF01145 SPFH domain / Band 7 family 23 197 6.0E-23 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS21115 e7308cfcb8f923061dafce3f12cbdd66 306 SMART SM00244 19 181 2.3E-7 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS19440 e58976b45f13172e5db6f92f8e22b090 703 SUPERFAMILY SSF109709 110 205 2.49E-18 T 06-07-2017 CAK95_RS19440 e58976b45f13172e5db6f92f8e22b090 703 SMART SM00470 14 115 1.6E-5 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS19440 e58976b45f13172e5db6f92f8e22b090 703 Pfam PF02195 ParB-like nuclease domain 16 114 1.8E-6 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS19440 e58976b45f13172e5db6f92f8e22b090 703 SUPERFAMILY SSF110849 15 105 4.01E-11 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS19440 e58976b45f13172e5db6f92f8e22b090 703 Gene3D G3DSA:3.90.1530.10 13 108 5.7E-10 T 06-07-2017 CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 Pfam PF00106 short chain dehydrogenase 7 177 2.1E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 SUPERFAMILY SSF51735 5 217 7.22E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 Gene3D G3DSA:3.40.50.720 5 220 4.8E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21845 0b09e1b9cf361eca51f559515ffb4d46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15570 8f5e47f61ce11a7d63771a981b02d814 399 Gene3D G3DSA:3.40.50.2300 160 313 2.2E-24 T 06-07-2017 CAK95_RS15570 8f5e47f61ce11a7d63771a981b02d814 399 Pfam PF13458 Periplasmic binding protein 27 380 1.9E-57 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS15570 8f5e47f61ce11a7d63771a981b02d814 399 SUPERFAMILY SSF53822 27 390 4.37E-70 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS15570 8f5e47f61ce11a7d63771a981b02d814 399 Gene3D G3DSA:3.40.50.2300 22 155 1.1E-35 T 06-07-2017 CAK95_RS15570 8f5e47f61ce11a7d63771a981b02d814 399 Gene3D G3DSA:3.40.50.2300 314 365 1.1E-35 T 06-07-2017 CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 SUPERFAMILY SSF48179 195 299 4.34E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 Gene3D G3DSA:1.10.1040.10 198 296 2.8E-21 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 196 295 1.3E-19 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 SUPERFAMILY SSF51735 2 192 4.56E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 Gene3D G3DSA:3.40.50.720 3 197 3.0E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 PIRSF PIRSF000105 1 323 1.1E-76 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAK95_RS27080 ff382f6b97310bd35159923af737c019 326 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 192 6.5E-47 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 Pfam PF00472 RF-1 domain 193 302 2.0E-38 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 Gene3D G3DSA:3.30.160.20 192 270 1.8E-34 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 SMART SM00937 49 159 9.6E-52 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 SUPERFAMILY SSF75620 2 328 2.35E-124 T 06-07-2017 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 329 5.2E-147 T 06-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 209 225 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 Pfam PF03462 PCRF domain 2 184 1.3E-56 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK95_RS25055 cc0a1b2a3fd5fc9e748215d0e86d8fdf 342 Gene3D G3DSA:1.20.58.410 1 80 5.4E-19 T 06-07-2017 CAK95_RS13090 911b850790c8f45974b54ed5eb1a0366 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 158 5.1E-24 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS01420 f84f47e3a721b64ed8d4a508b151a74a 73 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 19 38 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CAK95_RS01420 f84f47e3a721b64ed8d4a508b151a74a 73 SUPERFAMILY SSF54593 2 60 5.93E-10 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS01420 f84f47e3a721b64ed8d4a508b151a74a 73 Gene3D G3DSA:3.10.180.10 2 60 2.8E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS07505 47f7e72e8649ff69799c01a4d565fba6 193 Pfam PF00583 Acetyltransferase (GNAT) family 68 143 8.3E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS07505 47f7e72e8649ff69799c01a4d565fba6 193 SUPERFAMILY SSF55729 13 142 2.7E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS07505 47f7e72e8649ff69799c01a4d565fba6 193 Gene3D G3DSA:3.40.630.30 13 141 4.4E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Gene3D G3DSA:1.10.10.200 1 80 1.8E-35 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.3E-93 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Gene3D G3DSA:3.30.70.980 134 204 1.1E-22 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Gene3D G3DSA:3.30.1270.10 211 246 8.6E-41 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Gene3D G3DSA:3.30.1270.10 81 133 8.6E-41 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 SUPERFAMILY SSF75625 3 245 2.22E-92 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Pfam PF01709 Transcriptional regulator 5 236 1.8E-92 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS04090 38d73df72893b089be1de9acde9758df 248 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 34.097 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 Pfam PF00578 AhpC/TSA family 5 143 4.1E-30 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 Gene3D G3DSA:3.30.1020.10 165 219 2.5E-27 T 06-07-2017 CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 Gene3D G3DSA:3.40.30.10 3 164 2.4E-60 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 SUPERFAMILY SSF52833 3 217 3.12E-70 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 165 204 1.5E-14 T 06-07-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS21680 b99c8056937f6fdafc74db91defe0d20 219 PIRSF PIRSF000239 1 217 1.2E-75 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS12330 4ee694c85931f1390cfa53c83d7b8252 335 SUPERFAMILY SSF53850 123 294 4.83E-10 T 06-07-2017 CAK95_RS12330 4ee694c85931f1390cfa53c83d7b8252 335 PIRSF PIRSF017082 5 335 1.6E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12330 4ee694c85931f1390cfa53c83d7b8252 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 330 1.5E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00465 e583db8bbef5078c62f184c69d27da10 417 Gene3D G3DSA:1.20.1250.20 223 410 2.2E-18 T 06-07-2017 CAK95_RS00465 e583db8bbef5078c62f184c69d27da10 417 Gene3D G3DSA:1.20.1250.20 19 202 6.1E-21 T 06-07-2017 CAK95_RS00465 e583db8bbef5078c62f184c69d27da10 417 SUPERFAMILY SSF103473 9 406 1.7E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS00465 e583db8bbef5078c62f184c69d27da10 417 Pfam PF07690 Major Facilitator Superfamily 26 367 1.4E-33 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 Pfam PF13437 HlyD family secretion protein 288 391 2.7E-17 T 06-07-2017 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 Gene3D G3DSA:2.40.50.100 285 320 5.7E-15 T 06-07-2017 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 Gene3D G3DSA:2.40.50.100 58 89 5.7E-15 T 06-07-2017 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 Pfam PF13533 Biotin-lipoyl like 58 101 8.2E-6 T 06-07-2017 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 20 436 5.6E-121 T 06-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 357 380 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 25 48 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 300 321 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 333 357 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 415 435 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 67 87 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS07855 aeb122620446198e032a7ef00b8c7ccd 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 400 415 1.9E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 SUPERFAMILY SSF75516 10 173 2.75E-40 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 Gene3D G3DSA:3.30.450.80 12 183 3.8E-36 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 233 5.1E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 SMART SM00421 178 235 1.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 Gene3D G3DSA:1.10.10.10 184 239 2.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 223 2.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 211 2.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 195 2.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 Pfam PF03472 Autoinducer binding domain 25 166 3.1E-33 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS24640 d6cfce92ecac6a78d09ac0719b96695c 243 SUPERFAMILY SSF46894 164 240 6.12E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS28275 5ca1b06f09202a154b2fe6c6c1cacbc8 346 PIRSF PIRSF017082 13 344 4.5E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28275 5ca1b06f09202a154b2fe6c6c1cacbc8 346 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 70 338 2.2E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28275 5ca1b06f09202a154b2fe6c6c1cacbc8 346 SUPERFAMILY SSF53850 136 300 6.42E-12 T 06-07-2017 CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 SUPERFAMILY SSF55447 181 282 2.22E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 280 8.6E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 Gene3D G3DSA:3.30.43.10 1 53 1.5E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 Gene3D G3DSA:3.30.390.50 180 286 7.8E-23 T 06-07-2017 CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 SUPERFAMILY SSF56176 1 173 1.74E-48 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 Gene3D G3DSA:3.30.465.10 57 173 1.5E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 SMART SM01092 181 281 1.3E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28900 ca2a69525cf1983e237eb34da2d97e80 298 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 4.0E-44 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 Gene3D G3DSA:2.30.33.40 5 97 2.2E-40 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 SUPERFAMILY SSF50129 4 97 2.12E-36 T 06-07-2017 IPR011032 GroES-like CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 Hamap MF_00580 10 kDa chaperonin [groS]. 5 98 27.384 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 97 6.4E-37 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 PRINTS PR00297 10kDa chaperonin signature 28 49 3.8E-34 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 PRINTS PR00297 10kDa chaperonin signature 6 21 3.8E-34 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 PRINTS PR00297 10kDa chaperonin signature 63 75 3.8E-34 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 PRINTS PR00297 10kDa chaperonin signature 84 97 3.8E-34 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 SMART SM00883 5 97 9.6E-62 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS13160 8802f67c53099f8225c49e26ffb2e4f2 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 SUPERFAMILY SSF51120 553 728 1.78E-24 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1421 1439 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 648 665 6.5E-4 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1425 1441 0.0056 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1442 1458 0.005 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1352 1369 0.0028 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1211 1227 2.9 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1247 1263 0.25 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 81 95 3.3 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 62 78 0.0048 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 613 629 9.0E-4 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1388 1405 0.037 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1286 1302 34.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1407 1423 2.1 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 671 682 17.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 107 116 28.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1228 1245 0.0093 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 630 647 0.055 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 43 60 0.099 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1264 1281 0.0033 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1370 1387 0.031 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1194 1209 0.24 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 SUPERFAMILY SSF51120 1196 1287 1.66E-21 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1234 1252 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 SUPERFAMILY SSF51120 1376 1533 1.57E-29 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1207 1225 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1358 1376 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1367 1385 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 618 636 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 58 76 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 PRINTS PR00313 NodO calcium binding signature 50 61 2.2E-9 T 06-07-2017 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 PRINTS PR00313 NodO calcium binding signature 613 621 2.2E-9 T 06-07-2017 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 PRINTS PR00313 NodO calcium binding signature 71 79 2.2E-9 T 06-07-2017 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 PRINTS PR00313 NodO calcium binding signature 658 667 2.2E-9 T 06-07-2017 CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Gene3D G3DSA:2.150.10.10 1117 1323 1.7E-28 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Gene3D G3DSA:2.150.10.10 531 741 7.0E-24 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Gene3D G3DSA:2.150.10.10 33 176 3.1E-9 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 Gene3D G3DSA:2.150.10.10 1334 1519 4.2E-43 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1225 1243 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1376 1394 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1430 1448 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 SUPERFAMILY SSF51120 1285 1402 1.96E-20 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1252 1270 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 SUPERFAMILY SSF51120 14 168 8.76E-19 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1403 1421 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 636 654 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 645 663 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1394 1412 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21050 c08be79a89f424455941c4029fc656a9 1557 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1439 1457 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 SUPERFAMILY SSF52518 153 576 1.47E-92 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Pfam PF00676 Dehydrogenase E1 component 243 562 1.9E-59 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 SUPERFAMILY SSF52518 616 831 3.24E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 94 983 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 830 984 6.3E-51 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 13 52 7.7E-19 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Gene3D G3DSA:3.40.50.970 632 829 1.3E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Gene3D G3DSA:3.40.50.970 192 576 3.8E-78 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 Pfam PF02779 Transketolase, pyrimidine binding domain 631 826 2.0E-66 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 SMART SM00861 632 825 2.8E-60 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS07475 d075f79d69bdf8456a11d99f767e5b23 985 PIRSF PIRSF000157 1 985 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK95_RS22730 c957ad250352257d24c961960c9d41d5 263 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 198 262 4.5E-13 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS22730 c957ad250352257d24c961960c9d41d5 263 Gene3D G3DSA:3.30.1150.10 168 263 2.3E-19 T 06-07-2017 CAK95_RS22730 c957ad250352257d24c961960c9d41d5 263 Pfam PF13103 TonB C terminal 180 251 2.5E-11 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS22730 c957ad250352257d24c961960c9d41d5 263 SUPERFAMILY SSF74653 129 136 4.84E-17 T 06-07-2017 CAK95_RS22730 c957ad250352257d24c961960c9d41d5 263 SUPERFAMILY SSF74653 168 262 4.84E-17 T 06-07-2017 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 7.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 7.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 Gene3D G3DSA:1.10.10.60 13 67 6.2E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 69 5.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 Gene3D G3DSA:1.10.357.10 68 195 1.6E-12 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS08655 5d7997ab1f8cc0acac72ca42e6a98fa8 200 SUPERFAMILY SSF46689 12 84 7.48E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS18765 3a62c349ebe14ed5ba52cf5458d606ae 577 Pfam PF05872 Bacterial protein of unknown function (DUF853) 63 574 1.6E-217 T 06-07-2017 IPR033186 Helicase HerA-like C-terminal CAK95_RS18765 3a62c349ebe14ed5ba52cf5458d606ae 577 Gene3D G3DSA:3.40.50.300 43 159 1.1E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18765 3a62c349ebe14ed5ba52cf5458d606ae 577 Gene3D G3DSA:3.40.50.300 272 450 1.1E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18765 3a62c349ebe14ed5ba52cf5458d606ae 577 SUPERFAMILY SSF52540 45 451 5.06E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13805 6b5612addba1fcee25db288bc69d90f1 121 Pfam PF13788 Domain of unknown function (DUF4180) 10 119 9.8E-40 T 06-07-2017 IPR025438 Domain of unknown function DUF4180 CAK95_RS10160 78b3a0720c4eedc570b71a70108ebf77 334 Gene3D G3DSA:3.40.190.10 121 196 2.1E-16 T 06-07-2017 CAK95_RS10160 78b3a0720c4eedc570b71a70108ebf77 334 Pfam PF13379 NMT1-like family 23 264 1.1E-14 T 06-07-2017 CAK95_RS10160 78b3a0720c4eedc570b71a70108ebf77 334 SUPERFAMILY SSF53850 25 258 2.13E-27 T 06-07-2017 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 SMART SM00984 314 415 4.2E-35 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 SUPERFAMILY SSF48179 200 290 2.21E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 409 1.0E-119 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 PIRSF PIRSF000124 5 422 9.1E-58 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 315 415 1.2E-23 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 289 1.8E-25 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 PIRSF PIRSF500136 1 427 1.9E-143 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 SUPERFAMILY SSF52413 307 416 4.71E-25 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 176 8.7E-35 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 Gene3D G3DSA:3.40.50.720 3 221 2.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 269 3.5E-5 T 06-07-2017 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 31 3.5E-5 T 06-07-2017 CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 SUPERFAMILY SSF51735 5 192 6.22E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17755 cc1a32342bdcf94e366f75182a4db711 427 Gene3D G3DSA:3.40.50.720 231 416 7.6E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 Pfam PF00920 Dehydratase family 33 550 3.1E-193 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 461 472 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 16 553 4.5E-198 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 SUPERFAMILY SSF52016 375 553 6.28E-58 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 3 553 43.672 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01860 b3b598b5c1c4ec22c9fd601a22af7316 562 SUPERFAMILY SSF143975 2 374 4.71E-122 T 06-07-2017 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SMART SM00091 38 107 2.4 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SMART SM00091 159 229 4.8 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Gene3D G3DSA:3.30.450.20 50 153 2.3E-21 T 06-07-2017 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Gene3D G3DSA:3.30.450.20 172 274 1.6E-20 T 06-07-2017 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 503 532 1.8E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 455 484 1.8E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 349 378 1.8E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 426 453 1.8E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SUPERFAMILY SSF55785 49 151 3.66E-22 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SMART SM00086 112 154 0.0013 T 06-07-2017 IPR001610 PAC motif CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SMART SM00086 234 276 0.15 T 06-07-2017 IPR001610 PAC motif CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SUPERFAMILY SSF58104 294 576 2.79E-72 T 06-07-2017 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Pfam PF13426 PAS domain 177 274 9.6E-11 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Gene3D G3DSA:1.10.287.950 342 547 3.8E-61 T 06-07-2017 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 391 574 2.8E-57 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 50 156 2.8E-12 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 170 282 1.1E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 Pfam PF08448 PAS fold 50 154 5.2E-13 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SMART SM00283 328 575 2.2E-92 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS25175 f0b0eb211c145b0e1df767390322e59d 624 SUPERFAMILY SSF55785 172 273 2.44E-23 T 06-07-2017 IPR000014 PAS domain CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 175 4.2E-43 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 Gene3D G3DSA:3.30.43.10 1 54 4.9E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 SMART SM01092 181 283 4.0E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 181 281 1.1E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 Gene3D G3DSA:3.30.465.10 59 174 5.6E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 Gene3D G3DSA:3.30.390.50 179 286 1.3E-29 T 06-07-2017 CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 SUPERFAMILY SSF55447 180 283 4.32E-25 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS14270 eadd303d75e2fe128ddc2f19ca933a87 288 SUPERFAMILY SSF56176 1 175 1.17E-52 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 203 0.0014 T 06-07-2017 CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 2.9E-64 T 06-07-2017 CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 SUPERFAMILY SSF51735 5 249 4.31E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 Gene3D G3DSA:3.40.50.720 2 249 3.2E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00405 b9af884f1f5d2a667c878d0dd1dc1c24 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 SMART SM00922 160 257 4.0E-20 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 SUPERFAMILY SSF54826 1 136 1.04E-23 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 Pfam PF13378 Enolase C-terminal domain-like 164 373 8.9E-43 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 207 238 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 Gene3D G3DSA:3.30.390.10 1 121 5.5E-31 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 SUPERFAMILY SSF51604 122 374 4.45E-50 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS27555 41130457320afa278c24ccb234e327c0 386 Gene3D G3DSA:3.20.20.120 122 374 1.0E-55 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 5.1E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 5.1E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 222 232 5.1E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 5.1E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 284 295 5.1E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 Gene3D G3DSA:3.40.50.1370 145 292 2.1E-64 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 SUPERFAMILY SSF53671 2 306 2.88E-106 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 303 6.7E-52 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 4.3E-48 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.2E-30 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 4.2E-30 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 4.2E-30 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 267 4.2E-30 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 305 1.7E-116 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 306 77.768 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 Gene3D G3DSA:3.40.50.1370 3 144 7.6E-55 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS05850 796e562b6a37682a5810227849165ca4 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 SMART SM00382 348 535 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 Gene3D G3DSA:3.40.50.300 322 548 1.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 Pfam PF00664 ABC transporter transmembrane region 15 271 6.3E-12 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 Gene3D G3DSA:1.20.1560.10 14 303 1.4E-33 T 06-07-2017 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 15 548 6.9E-182 T 06-07-2017 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 SUPERFAMILY SSF90123 14 307 2.88E-37 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 SUPERFAMILY SSF52540 313 546 3.26E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21055 bfd28a91b964bb6ca18db41076d379fc 566 Pfam PF00005 ABC transporter 340 487 2.6E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13180 534e8f186c544c6e98840ecc4c123f1d 400 Gene3D G3DSA:1.20.1250.20 12 195 3.7E-9 T 06-07-2017 CAK95_RS13180 534e8f186c544c6e98840ecc4c123f1d 400 SUPERFAMILY SSF103473 12 396 3.79E-21 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82866 792 1021 5.36E-42 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Gene3D G3DSA:1.10.3850.10 800 1020 8.2E-44 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Gene3D G3DSA:1.10.3850.10 277 498 6.4E-51 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Pfam PF00873 AcrB/AcrD/AcrF family 7 1015 2.8E-239 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Gene3D G3DSA:3.30.2090.10 711 797 2.3E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82714 711 795 3.01E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Gene3D G3DSA:3.30.70.1430 45 143 8.5E-23 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82714 184 265 1.96E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 2.9E-34 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82693 45 129 4.19E-19 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1020 2.1E-228 T 06-07-2017 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82693 139 183 6.02E-16 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82693 269 319 6.02E-16 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 SUPERFAMILY SSF82866 293 498 2.09E-37 T 06-07-2017 CAK95_RS12605 d4500c500c9bdeb9735c6494d44706d9 1046 Gene3D G3DSA:3.30.2090.10 184 265 4.7E-12 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Gene3D G3DSA:3.40.190.10 252 324 9.9E-22 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Gene3D G3DSA:3.40.190.10 109 126 9.9E-22 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 359 1.8E-46 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 SUPERFAMILY SSF53850 245 361 6.92E-48 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 SUPERFAMILY SSF53850 1 132 6.92E-48 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Gene3D G3DSA:1.10.287.70 154 251 7.7E-7 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Gene3D G3DSA:3.40.190.10 325 361 5.6E-30 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 Gene3D G3DSA:3.40.190.10 33 108 5.6E-30 T 06-07-2017 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 SMART SM00079 33 360 4.1E-7 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAK95_RS27995 4b72ad23b2205745251489c4b2f3252e 362 SMART SM00062 33 361 4.1E-14 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS20075 3ebfd70e05869d699c0b8a94bb794c91 232 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 42 221 2.0E-59 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAK95_RS20075 3ebfd70e05869d699c0b8a94bb794c91 232 Pfam PF02666 Phosphatidylserine decarboxylase 48 217 2.9E-31 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAK95_RS20075 3ebfd70e05869d699c0b8a94bb794c91 232 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 13 221 38.501 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 SUPERFAMILY SSF46689 15 96 8.25E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 SUPERFAMILY SSF48498 92 206 1.96E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 Gene3D G3DSA:1.10.357.10 71 207 4.2E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 Gene3D G3DSA:1.10.10.60 21 70 2.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 7.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04380 d9458007495e0d14079456be191da2e5 225 Pfam PF08359 YsiA-like protein, C-terminal region 78 180 8.2E-7 T 06-07-2017 IPR013570 Transcription regulator YsiA, C-terminal CAK95_RS17285 8bf7b5fcbd5d66a945e9320408df75a7 289 Gene3D G3DSA:3.40.190.10 101 197 3.2E-8 T 06-07-2017 CAK95_RS17285 8bf7b5fcbd5d66a945e9320408df75a7 289 SUPERFAMILY SSF53850 7 288 3.53E-19 T 06-07-2017 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 70 1.4E-33 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 Pfam PF01197 Ribosomal protein L31 1 69 3.2E-26 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 PRINTS PR01249 Ribosomal protein L31 signature 50 68 1.2E-8 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.2E-8 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 72 26.053 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 SUPERFAMILY SSF143800 1 71 2.04E-21 T 06-07-2017 CAK95_RS04215 7bb867740c655f4818ca7ddca4f81457 77 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 60 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04085 f948fdee1f8d8a460f83d4039cf32457 404 Pfam PF02417 Chromate transporter 232 398 6.9E-40 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS04085 f948fdee1f8d8a460f83d4039cf32457 404 Pfam PF02417 Chromate transporter 17 181 1.2E-34 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS04085 f948fdee1f8d8a460f83d4039cf32457 404 PIRSF PIRSF004810 2 404 2.7E-131 T 06-07-2017 IPR014047 Chromate transporter, long chain CAK95_RS04085 f948fdee1f8d8a460f83d4039cf32457 404 TIGRFAM TIGR00937 2A51: chromate efflux transporter 22 398 8.8E-104 T 06-07-2017 IPR014047 Chromate transporter, long chain CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 Gene3D G3DSA:3.40.50.2300 7 135 5.1E-37 T 06-07-2017 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 Gene3D G3DSA:3.40.50.2300 289 350 5.1E-37 T 06-07-2017 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 Pfam PF13458 Periplasmic binding protein 12 362 1.8E-64 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 SUPERFAMILY SSF53822 12 366 1.15E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 Gene3D G3DSA:3.40.50.2300 153 288 2.9E-20 T 06-07-2017 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 35 51 4.1E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 72 4.1E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 331 346 4.1E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16135 d7af9d96a52d22fdb22492eada0a1dcc 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 13 29 4.1E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS05755 a39c2adc7729760e3ee44d4c66677074 385 Gene3D G3DSA:3.40.50.2300 142 295 2.5E-25 T 06-07-2017 CAK95_RS05755 a39c2adc7729760e3ee44d4c66677074 385 Pfam PF13458 Periplasmic binding protein 19 358 2.2E-69 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS05755 a39c2adc7729760e3ee44d4c66677074 385 Gene3D G3DSA:3.40.50.2300 296 346 2.6E-37 T 06-07-2017 CAK95_RS05755 a39c2adc7729760e3ee44d4c66677074 385 Gene3D G3DSA:3.40.50.2300 14 141 2.6E-37 T 06-07-2017 CAK95_RS05755 a39c2adc7729760e3ee44d4c66677074 385 SUPERFAMILY SSF53822 19 366 1.1E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS10130 4d67b355e667c149afaa1bc029cf3848 395 Pfam PF13458 Periplasmic binding protein 13 349 9.4E-65 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS10130 4d67b355e667c149afaa1bc029cf3848 395 Gene3D G3DSA:3.40.50.2300 8 135 2.6E-31 T 06-07-2017 CAK95_RS10130 4d67b355e667c149afaa1bc029cf3848 395 Gene3D G3DSA:3.40.50.2300 285 338 2.6E-31 T 06-07-2017 CAK95_RS10130 4d67b355e667c149afaa1bc029cf3848 395 SUPERFAMILY SSF53822 13 376 6.39E-71 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS10130 4d67b355e667c149afaa1bc029cf3848 395 Gene3D G3DSA:3.40.50.2300 138 284 1.1E-22 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 PRINTS PR00154 AMP-binding signature 162 170 3.8E-5 T 06-07-2017 IPR020459 AMP-binding CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 PRINTS PR00154 AMP-binding signature 150 161 3.8E-5 T 06-07-2017 IPR020459 AMP-binding CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Gene3D G3DSA:2.30.38.10 321 403 6.2E-18 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 495 1.1E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Pfam PF00501 AMP-binding enzyme 17 412 2.3E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Gene3D G3DSA:3.30.300.30 407 503 2.2E-23 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Gene3D G3DSA:3.40.50.980 162 320 2.9E-36 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 Gene3D G3DSA:3.40.50.980 8 161 2.1E-41 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 SUPERFAMILY SSF56801 5 505 1.96E-139 T 06-07-2017 CAK95_RS11890 3ba4348f00ac95eafe4faacb31df5bf6 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 Gene3D G3DSA:3.50.50.60 3 125 1.3E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 Gene3D G3DSA:3.50.50.60 247 292 1.3E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 Gene3D G3DSA:3.50.50.60 126 222 4.6E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 284 2.4E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 3.1E-13 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 276 3.1E-13 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 3.1E-13 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.1E-13 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 SUPERFAMILY SSF51905 3 290 4.63E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.3E-12 T 06-07-2017 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 7.3E-12 T 06-07-2017 CAK95_RS26265 82a3a5e8469f9959f2bf05ac3be8f0a4 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 7.3E-12 T 06-07-2017 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 Pfam PF00561 alpha/beta hydrolase fold 32 146 5.7E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 SUPERFAMILY SSF53474 6 298 6.06E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 5.7E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 5.7E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 5.7E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 Gene3D G3DSA:3.40.50.1820 8 297 3.4E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00412 Epoxide hydrolase signature 106 119 6.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00412 Epoxide hydrolase signature 38 56 6.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS13375 2b370d14c491f219768e30c4c5a6667c 299 PRINTS PR00412 Epoxide hydrolase signature 274 296 6.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 142 172 2.0E-9 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 PRINTS PR00502 NUDIX hydrolase family signature 203 217 7.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 PRINTS PR00502 NUDIX hydrolase family signature 217 232 7.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 ProSitePatterns PS00893 Nudix box signature. 208 229 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 54 140 1.5E-6 T 06-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 SUPERFAMILY SSF55811 129 308 4.06E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 Gene3D G3DSA:3.90.79.10 138 311 2.3E-53 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS06610 df5081973b671a7118cf7317726af391 318 Pfam PF00293 NUDIX domain 178 283 4.2E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS08155 f130b67811bac3131d93614eeb1c375c 292 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 33 201 5.2E-57 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CAK95_RS08155 f130b67811bac3131d93614eeb1c375c 292 SUPERFAMILY SSF110849 36 177 3.82E-34 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS08155 f130b67811bac3131d93614eeb1c375c 292 Pfam PF02195 ParB-like nuclease domain 37 127 1.5E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS08155 f130b67811bac3131d93614eeb1c375c 292 SMART SM00470 35 127 5.1E-32 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS08155 f130b67811bac3131d93614eeb1c375c 292 Gene3D G3DSA:3.90.1530.10 30 133 7.7E-37 T 06-07-2017 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 SUPERFAMILY SSF53223 6 107 4.95E-32 T 06-07-2017 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 Gene3D G3DSA:3.40.50.720 112 270 3.4E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 Gene3D G3DSA:3.40.192.10 8 111 1.6E-38 T 06-07-2017 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 SUPERFAMILY SSF51735 108 270 4.26E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 1.3E-25 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 274 3.6E-72 T 06-07-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 278 32.883 T 06-07-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAK95_RS10050 0c30e7e7d5c3513d3011755a442890f4 280 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 129 198 1.5E-7 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CAK95_RS17300 ba99311090a61a3a1fd6ea0b9aac91aa 386 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 345 1.9E-39 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS17300 ba99311090a61a3a1fd6ea0b9aac91aa 386 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 355 3.6E-134 T 06-07-2017 IPR017778 ABC transporter, urea, permease protein, UrtC CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Pfam PF00873 AcrB/AcrD/AcrF family 4 1015 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:3.30.2090.10 709 798 3.2E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:1.20.1640.10 285 501 1.4E-58 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82693 40 135 8.02E-23 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:3.30.2090.10 184 265 8.4E-16 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82714 710 795 8.5E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:3.30.70.1430 40 141 2.5E-28 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82693 560 658 1.54E-14 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:3.30.70.1430 563 656 4.2E-9 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82866 290 490 1.7E-47 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82693 135 182 3.14E-22 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82693 268 324 3.14E-22 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 614 628 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 8.6E-77 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 Gene3D G3DSA:1.10.3850.10 802 1017 1.0E-52 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82866 795 1017 1.31E-43 T 06-07-2017 CAK95_RS23970 5aae12cf4ef413bbc99b8f80fd6e67f6 1045 SUPERFAMILY SSF82714 184 266 4.97E-15 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS28230 f216234ae79892a719ac9ac15ce6cc63 322 PIRSF PIRSF017082 1 321 4.5E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28230 f216234ae79892a719ac9ac15ce6cc63 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 1.0E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28230 f216234ae79892a719ac9ac15ce6cc63 322 SUPERFAMILY SSF53850 108 287 8.2E-9 T 06-07-2017 CAK95_RS05205 fdfe067bc77ec8e78b55f724b6788156 325 PIRSF PIRSF017082 1 325 2.1E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05205 fdfe067bc77ec8e78b55f724b6788156 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 3.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05205 fdfe067bc77ec8e78b55f724b6788156 325 SUPERFAMILY SSF53850 90 284 5.97E-10 T 06-07-2017 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 Pfam PF00453 Ribosomal protein L20 3 108 1.8E-46 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 Gene3D G3DSA:1.10.1900.20 55 117 8.0E-28 T 06-07-2017 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 PRINTS PR00062 Ribosomal protein L20 signature 12 41 4.5E-36 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 PRINTS PR00062 Ribosomal protein L20 signature 42 71 4.5E-36 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 PRINTS PR00062 Ribosomal protein L20 signature 75 101 4.5E-36 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.529 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.2E-47 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 SUPERFAMILY SSF74731 3 117 1.57E-47 T 06-07-2017 CAK95_RS09030 c4a39f9e0a9056ba9f69b70f3e869c34 121 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 6.0E-11 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Pfam PF12838 4Fe-4S dicluster domain 501 575 1.4E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:3.30.70.20 510 591 1.1E-14 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:3.50.50.60 343 418 5.1E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 561 572 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 SUPERFAMILY SSF46548 402 518 5.75E-11 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 SUPERFAMILY SSF46548 17 119 6.28E-18 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:3.50.50.60 204 342 3.7E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 501 512 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:3.50.50.60 110 203 1.7E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 SUPERFAMILY SSF51971 107 350 1.35E-47 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 PRINTS PR00419 Adrenodoxin reductase family signature 241 255 2.2E-14 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 PRINTS PR00419 Adrenodoxin reductase family signature 110 132 2.2E-14 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 PRINTS PR00419 Adrenodoxin reductase family signature 133 146 2.2E-14 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 109 405 1.6E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 17 93 1.6E-16 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 SUPERFAMILY SSF54862 499 586 9.42E-15 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:1.10.1060.10 17 109 5.6E-27 T 06-07-2017 CAK95_RS21505 9ff178e66083f9ac8ea50cceee410222 600 Gene3D G3DSA:3.30.70.20 482 509 9.2E-7 T 06-07-2017 CAK95_RS02970 419e0d1c4a0f1c479c6aae83cba521ca 440 Pfam PF00239 Resolvase, N terminal domain 12 163 1.9E-38 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02970 419e0d1c4a0f1c479c6aae83cba521ca 440 SUPERFAMILY SSF53041 10 164 4.05E-39 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02970 419e0d1c4a0f1c479c6aae83cba521ca 440 Gene3D G3DSA:3.40.50.1390 10 147 1.5E-34 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02970 419e0d1c4a0f1c479c6aae83cba521ca 440 SMART SM00857 11 164 5.5E-61 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02970 419e0d1c4a0f1c479c6aae83cba521ca 440 Pfam PF07508 Recombinase 185 270 2.0E-12 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 SUPERFAMILY SSF52402 139 282 8.37E-30 T 06-07-2017 CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 Gene3D G3DSA:3.40.50.620 1 127 1.3E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 Pfam PF00582 Universal stress protein family 1 130 7.2E-27 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 Pfam PF00582 Universal stress protein family 139 282 3.2E-24 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 PRINTS PR01438 Universal stress protein signature 242 254 3.0E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 PRINTS PR01438 Universal stress protein signature 139 157 3.0E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 PRINTS PR01438 Universal stress protein signature 260 282 3.0E-16 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 SUPERFAMILY SSF52402 1 131 1.4E-31 T 06-07-2017 CAK95_RS09100 9f0e066b3e38b03ad8c61ea12839bb7b 292 Gene3D G3DSA:3.40.50.620 128 282 8.4E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 5.4E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 SUPERFAMILY SSF52172 4 132 2.99E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 SUPERFAMILY SSF46894 133 234 6.52E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 Gene3D G3DSA:1.10.10.10 133 236 8.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 Pfam PF00072 Response regulator receiver domain 8 118 2.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 SMART SM00448 6 117 2.0E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 Gene3D G3DSA:3.40.50.2300 5 129 3.2E-40 T 06-07-2017 CAK95_RS05020 4b9cad597c13070fbcfd544e38127fb8 243 SMART SM00862 156 232 3.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 Gene3D G3DSA:3.40.640.10 43 290 5.1E-89 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 224 243 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 SUPERFAMILY SSF53383 10 408 8.78E-129 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 PIRSF PIRSF005572 29 412 6.5E-51 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 Pfam PF00266 Aminotransferase class-V 32 401 1.7E-148 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 Gene3D G3DSA:3.90.1150.10 291 406 4.5E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS24985 cd634b5feef4eecb7bd477f2641b6fba 413 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 14 413 5.1E-180 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK95_RS27305 46e3636fb17592bebbcdc395edef7bc3 207 Gene3D G3DSA:1.20.1290.10 30 177 1.2E-39 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS27305 46e3636fb17592bebbcdc395edef7bc3 207 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 124 1.0E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS27305 46e3636fb17592bebbcdc395edef7bc3 207 SUPERFAMILY SSF69118 1 176 8.11E-49 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS27305 46e3636fb17592bebbcdc395edef7bc3 207 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 4 171 6.8E-24 T 06-07-2017 IPR010195 Uncharacterised peroxidase-related CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:1.10.287.610 11 80 7.0E-25 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:3.30.470.30 136 268 2.2E-52 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Pfam PF12826 Helix-hairpin-helix motif 547 620 8.1E-12 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Hamap MF_01588 DNA ligase [ligA]. 17 712 48.267 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SUPERFAMILY SSF52113 636 711 3.36E-18 T 06-07-2017 IPR001357 BRCT domain CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:2.40.50.140 336 418 3.9E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 642 709 2.2E-11 T 06-07-2017 IPR001357 BRCT domain CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:3.40.50.10190 637 712 3.8E-23 T 06-07-2017 IPR001357 BRCT domain CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SUPERFAMILY SSF47781 430 625 2.85E-43 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 132 161 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SUPERFAMILY SSF56091 15 331 3.6E-118 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SMART SM00532 18 481 4.9E-230 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 347 362 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 19 334 1.1E-125 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:1.10.150.20 468 539 3.5E-21 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Gene3D G3DSA:1.10.150.20 541 626 7.0E-24 T 06-07-2017 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 26 708 9.3E-232 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SUPERFAMILY SSF50249 334 428 1.56E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 SMART SM00292 638 714 4.2E-8 T 06-07-2017 IPR001357 BRCT domain CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 PIRSF PIRSF001604 11 714 2.5E-224 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK95_RS01735 b62d12e5b99c08820749c29751763464 714 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 338 425 2.9E-31 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 SUPERFAMILY SSF51905 9 164 1.55E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 SUPERFAMILY SSF51905 257 351 1.55E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 Pfam PF01494 FAD binding domain 9 304 3.4E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 Gene3D G3DSA:3.50.50.60 9 169 7.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 Gene3D G3DSA:3.50.50.60 258 333 7.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.6E-16 T 06-07-2017 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 5.6E-16 T 06-07-2017 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 5.6E-16 T 06-07-2017 CAK95_RS27340 87b4dc54dc36bdc5cd13c2051ef26d22 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 5.6E-16 T 06-07-2017 CAK95_RS04470 d0b1424b4aafc3cdb7383c3f942a311d 515 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 26 467 3.9E-88 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS04470 d0b1424b4aafc3cdb7383c3f942a311d 515 Gene3D G3DSA:3.40.1670.10 353 466 1.3E-27 T 06-07-2017 CAK95_RS04470 d0b1424b4aafc3cdb7383c3f942a311d 515 SUPERFAMILY SSF143968 334 498 1.09E-38 T 06-07-2017 CAK95_RS04470 d0b1424b4aafc3cdb7383c3f942a311d 515 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 30 440 3.3E-116 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS04470 d0b1424b4aafc3cdb7383c3f942a311d 515 SUPERFAMILY SSF50475 23 325 2.63E-80 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS09605 372d5a167e2ee6752973dd8e066f00fa 99 Pfam PF01541 GIY-YIG catalytic domain 4 44 6.2E-6 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS09605 372d5a167e2ee6752973dd8e066f00fa 99 SUPERFAMILY SSF82771 3 46 3.14E-7 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 ProSitePatterns PS00934 Glyoxalase I signature 1. 169 190 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 Gene3D G3DSA:3.10.180.10 2 146 1.1E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 Gene3D G3DSA:3.10.180.10 161 306 1.6E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 SUPERFAMILY SSF54593 163 306 1.25E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 SUPERFAMILY SSF54593 1 194 1.22E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 167 302 1.8E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS00860 aeb5c75ba45831c90bf092b5383069b7 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 144 4.6E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 Pfam PF00005 ABC transporter 354 502 2.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 SMART SM00382 363 550 3.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 Pfam PF00664 ABC transporter transmembrane region 28 286 1.7E-17 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 SUPERFAMILY SSF90123 18 326 3.27E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 Gene3D G3DSA:3.40.50.300 337 553 1.6E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 Gene3D G3DSA:1.20.1560.10 20 319 5.5E-39 T 06-07-2017 CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 SUPERFAMILY SSF52540 327 552 1.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09845 0f668912082b14a6f4af45e9175f3d1e 584 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 19 564 4.0E-222 T 06-07-2017 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Pfam PF02310 B12 binding domain 760 849 4.0E-18 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SMART SM01018 664 747 3.1E-44 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Gene3D G3DSA:3.20.20.330 14 372 3.3E-122 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SUPERFAMILY SSF47644 659 746 2.48E-28 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Pfam PF02607 B12 binding domain 668 739 4.8E-24 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Pfam PF02574 Homocysteine S-methyltransferase 27 334 4.7E-88 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Gene3D G3DSA:3.20.20.20 373 645 2.9E-113 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 PIRSF PIRSF000381 11 1208 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SUPERFAMILY SSF52242 754 906 3.92E-44 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Gene3D G3DSA:3.10.196.10 971 1246 4.1E-111 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SUPERFAMILY SSF82282 18 408 3.14E-114 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 952 1221 1.4E-123 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Pfam PF00809 Pterin binding enzyme 369 607 9.2E-60 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Gene3D G3DSA:3.40.50.280 757 907 2.0E-61 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 Gene3D G3DSA:1.10.1240.10 658 744 2.7E-38 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SUPERFAMILY SSF51717 365 639 3.01E-90 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 TIGRFAM TIGR02082 metH: methionine synthase 23 1205 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS01840 b5147cbab4f52c90a063b290afe95642 1252 SUPERFAMILY SSF56507 915 1239 1.18E-128 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Pfam PF12838 4Fe-4S dicluster domain 561 620 1.8E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 996 1061 8.0E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Gene3D G3DSA:3.30.70.20 561 619 8.2E-9 T 06-07-2017 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 SUPERFAMILY SSF54292 966 1072 1.7E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 561 572 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 1023 1031 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 SUPERFAMILY SSF52343 856 974 1.7E-23 T 06-07-2017 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 SUPERFAMILY SSF54862 558 648 2.02E-13 T 06-07-2017 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Pfam PF13486 Reductive dehalogenase subunit 443 546 3.2E-7 T 06-07-2017 IPR028894 Reductive dehalogenase domain CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Gene3D G3DSA:3.10.20.30 972 1070 7.7E-21 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Gene3D G3DSA:3.40.50.80 857 971 1.0E-21 T 06-07-2017 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 867 886 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 845 859 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 892 901 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 944 952 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 795 807 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 807 821 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 785 795 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 PRINTS PR00409 Phthalate dioxygenase reductase family signature 831 845 1.9E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 SUPERFAMILY SSF63380 757 855 7.35E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS28565 c314434907f7360156c4d10deabb73ae 1074 Gene3D G3DSA:2.40.30.10 760 856 2.6E-26 T 06-07-2017 CAK95_RS26545 dafe88c9059b0bf9279d5f9ad17f084a 409 Gene3D G3DSA:3.40.1280.10 18 176 1.8E-32 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS26545 dafe88c9059b0bf9279d5f9ad17f084a 409 Pfam PF00588 SpoU rRNA Methylase family 19 169 4.7E-31 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK95_RS26545 dafe88c9059b0bf9279d5f9ad17f084a 409 SUPERFAMILY SSF75217 17 176 1.05E-32 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS26545 dafe88c9059b0bf9279d5f9ad17f084a 409 Pfam PF04480 Protein of unknown function (DUF559) 293 396 2.4E-16 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK95_RS26545 dafe88c9059b0bf9279d5f9ad17f084a 409 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 20 249 2.2E-53 T 06-07-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Gene3D G3DSA:2.170.130.10 147 259 9.8E-23 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SMART SM00965 65 116 2.3E-12 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Pfam PF00593 TonB dependent receptor 636 906 1.6E-27 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SUPERFAMILY SSF56925 932 1140 1.8E-21 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SUPERFAMILY SSF56925 1168 1184 1.8E-21 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Gene3D G3DSA:2.40.170.20 330 363 2.1E-72 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Gene3D G3DSA:2.40.170.20 260 283 2.1E-72 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Gene3D G3DSA:2.40.170.20 395 909 2.1E-72 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Gene3D G3DSA:2.40.160.20 932 1184 3.9E-28 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Pfam PF07660 Secretin and TonB N terminus short domain 67 114 2.0E-7 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Pfam PF07715 TonB-dependent Receptor Plug Domain 147 250 1.2E-11 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SUPERFAMILY SSF56935 321 360 5.49E-80 T 06-07-2017 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SUPERFAMILY SSF56935 121 280 5.49E-80 T 06-07-2017 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 SUPERFAMILY SSF56935 413 909 5.49E-80 T 06-07-2017 CAK95_RS04835 45bb552a2c2e9b92888d09c4019d3f28 1184 Pfam PF13505 Outer membrane protein beta-barrel domain 916 1147 1.3E-15 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 Gene3D G3DSA:1.10.3480.10 71 257 5.8E-43 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 SUPERFAMILY SSF47413 6 59 1.97E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 Pfam PF02613 Nitrate reductase delta subunit 106 224 3.3E-25 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 Gene3D G3DSA:1.10.260.40 6 60 2.4E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 SUPERFAMILY SSF89155 71 255 7.46E-47 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone CAK95_RS27840 b9db8272953cb7d2d44166ad594ef14b 258 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 6 60 1.2E-16 T 06-07-2017 IPR031856 Putative bacterial antitoxin YdaS CAK95_RS02150 026f4b91db921701525228d5768be940 272 SUPERFAMILY SSF55781 87 267 1.11E-31 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS02150 026f4b91db921701525228d5768be940 272 Gene3D G3DSA:1.10.10.10 18 89 7.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02150 026f4b91db921701525228d5768be940 272 SUPERFAMILY SSF46785 22 95 1.67E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02150 026f4b91db921701525228d5768be940 272 Gene3D G3DSA:3.30.450.40 90 267 2.1E-37 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS02150 026f4b91db921701525228d5768be940 272 Pfam PF09339 IclR helix-turn-helix domain 24 74 1.9E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS02150 026f4b91db921701525228d5768be940 272 Pfam PF01614 Bacterial transcriptional regulator 138 264 9.0E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS02150 026f4b91db921701525228d5768be940 272 SMART SM00346 22 111 1.6E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 SUPERFAMILY SSF46785 1 86 6.21E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 Gene3D G3DSA:3.40.190.10 175 263 4.7E-22 T 06-07-2017 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 SUPERFAMILY SSF53850 90 294 1.63E-38 T 06-07-2017 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 Gene3D G3DSA:3.40.190.10 90 174 2.1E-16 T 06-07-2017 CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 Pfam PF03466 LysR substrate binding domain 88 293 1.9E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS15535 49680cb23fe62004cf6754af68334303 303 Gene3D G3DSA:1.10.10.10 1 86 9.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00290 c1cbcf8d86e2201a7a4b1bc0f05c3def 395 Pfam PF13458 Periplasmic binding protein 23 371 9.2E-54 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS00290 c1cbcf8d86e2201a7a4b1bc0f05c3def 395 SUPERFAMILY SSF53822 23 374 3.66E-65 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS00290 c1cbcf8d86e2201a7a4b1bc0f05c3def 395 Gene3D G3DSA:3.40.50.2300 18 154 8.7E-34 T 06-07-2017 CAK95_RS00290 c1cbcf8d86e2201a7a4b1bc0f05c3def 395 Gene3D G3DSA:3.40.50.2300 309 358 8.7E-34 T 06-07-2017 CAK95_RS00290 c1cbcf8d86e2201a7a4b1bc0f05c3def 395 Gene3D G3DSA:3.40.50.2300 171 308 4.4E-20 T 06-07-2017 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Gene3D G3DSA:3.30.43.10 19 89 6.6E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 SUPERFAMILY SSF56194 198 303 6.67E-36 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 SUPERFAMILY SSF56176 26 212 9.81E-40 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 300 2.6E-28 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 94.513 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 27 302 1.7E-51 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Gene3D G3DSA:3.90.78.10 230 302 3.7E-30 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Pfam PF01565 FAD binding domain 40 167 3.6E-18 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS01780 f75561fd25131637f083d5a1bfbe785d 305 Gene3D G3DSA:3.30.465.10 92 229 5.6E-35 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS04320 86562b9c9a655c62204923dfebd896c9 254 Pfam PF01925 Sulfite exporter TauE/SafE 14 242 8.1E-26 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Gene3D G3DSA:3.30.450.40 11 164 1.8E-40 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 625 643 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 SUPERFAMILY SSF52009 302 421 5.76E-30 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Gene3D G3DSA:1.10.274.10 200 310 5.6E-32 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 SUPERFAMILY SSF47831 200 320 1.07E-28 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Pfam PF00391 PEP-utilising enzyme, mobile domain 330 403 7.2E-19 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 429 716 2.6E-83 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 183 723 8.8E-125 T 06-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Gene3D G3DSA:3.20.20.60 433 735 2.0E-84 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 678 690 9.5E-16 T 06-07-2017 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 625 640 9.5E-16 T 06-07-2017 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 471 490 9.5E-16 T 06-07-2017 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 642 657 9.5E-16 T 06-07-2017 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Pfam PF01590 GAF domain 26 157 2.4E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 SUPERFAMILY SSF55781 12 160 7.41E-25 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Pfam PF05524 PEP-utilising enzyme, N-terminal 185 303 1.1E-23 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 Gene3D G3DSA:3.50.30.10 311 432 7.0E-35 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 SMART SM00065 24 170 8.2E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK95_RS10390 6b2623935a237bcfac510f8d9768f257 755 SUPERFAMILY SSF51621 427 723 2.54E-88 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 SUPERFAMILY SSF51905 246 340 9.62E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 SUPERFAMILY SSF51905 2 150 9.62E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Gene3D G3DSA:3.50.50.60 96 157 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Gene3D G3DSA:3.50.50.60 249 371 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Gene3D G3DSA:3.50.50.60 1 42 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 SUPERFAMILY SSF51395 392 750 1.64E-119 T 06-07-2017 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.6E-7 T 06-07-2017 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 3.6E-7 T 06-07-2017 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 290 3.6E-7 T 06-07-2017 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 396 727 1.2E-68 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Gene3D G3DSA:3.20.20.70 389 741 6.0E-127 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS09905 74870d9552b6fbff0b3495d2ed34105e 781 Pfam PF01494 FAD binding domain 2 320 6.1E-11 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 SUPERFAMILY SSF55681 118 417 7.08E-98 T 06-07-2017 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 SUPERFAMILY SSF46589 1 114 9.42E-28 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 39.813 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 1.3E-157 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 Gene3D G3DSA:3.30.930.10 107 420 5.5E-141 T 06-07-2017 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 1.8E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 1.8E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 1.8E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 1.8E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 1.8E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 Gene3D G3DSA:1.10.287.40 1 106 2.1E-28 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 PIRSF PIRSF001529 1 425 4.9E-166 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 399 2.6E-36 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23900 4fc029d8e64bf14578412d2935a049f4 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 2.8E-30 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 128 1.9E-15 T 06-07-2017 IPR000014 PAS domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 Gene3D G3DSA:3.30.450.20 9 125 7.2E-23 T 06-07-2017 CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 SMART SM00091 7 73 3.6E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 301 2.6E-52 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 SUPERFAMILY SSF55073 139 300 4.87E-47 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 SMART SM00086 80 123 7.5E-6 T 06-07-2017 IPR001610 PAC motif CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 SMART SM00267 123 303 3.6E-61 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 Gene3D G3DSA:3.30.70.270 136 301 2.1E-54 T 06-07-2017 CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 Pfam PF00990 Diguanylate cyclase, GGDEF domain 134 299 1.9E-49 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 SUPERFAMILY SSF55785 12 125 3.54E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS23525 098a67649b3f4ceabd007436878102db 315 Pfam PF08447 PAS fold 30 115 3.0E-9 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 258 274 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 Gene3D G3DSA:3.40.50.720 152 325 2.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 Gene3D G3DSA:3.40.50.720 63 151 1.7E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 63 347 1.0E-9 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 148 323 7.1E-53 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 SUPERFAMILY SSF51735 140 324 1.03E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17690 db43427f81ac4b6f06a247b758d59e46 350 SUPERFAMILY SSF52283 63 174 1.4E-16 T 06-07-2017 CAK95_RS06030 cb009482ff2b1291fe4ecfb03c936e6c 170 Gene3D G3DSA:1.20.120.160 47 127 1.4E-5 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS06030 cb009482ff2b1291fe4ecfb03c936e6c 170 SUPERFAMILY SSF47226 46 137 1.47E-5 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS18525 0023d159c871395b140ddbfd07ee7ed8 163 Gene3D G3DSA:1.20.1260.10 2 163 6.8E-66 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS18525 0023d159c871395b140ddbfd07ee7ed8 163 Pfam PF05974 Domain of unknown function (DUF892) 7 163 3.9E-62 T 06-07-2017 IPR010287 Domain of unknown function DUF892 CAK95_RS18525 0023d159c871395b140ddbfd07ee7ed8 163 SUPERFAMILY SSF47240 3 155 1.68E-55 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 Gene3D G3DSA:1.10.101.10 331 390 7.4E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 SUPERFAMILY SSF47090 323 390 3.45E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 Pfam PF13406 Transglycosylase SLT domain 23 314 3.5E-99 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 SUPERFAMILY SSF53955 10 319 2.06E-91 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 Gene3D G3DSA:1.10.530.10 206 318 5.8E-57 T 06-07-2017 CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 Gene3D G3DSA:1.10.530.10 67 124 5.8E-57 T 06-07-2017 CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 Pfam PF01471 Putative peptidoglycan binding domain 339 390 3.7E-9 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS05030 92b7d171922530254d636bd11382a96f 393 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 23 318 4.3E-102 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 SUPERFAMILY SSF48008 78 222 2.88E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 SUPERFAMILY SSF46785 3 100 1.03E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 3.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 3.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 Gene3D G3DSA:1.10.10.10 2 72 1.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 SMART SM00345 13 71 8.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 Pfam PF07729 FCD domain 81 215 9.3E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 Gene3D G3DSA:1.20.120.530 77 228 6.0E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 71 1.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28540 f66aa524be76c9515662f526d534de05 243 SMART SM00895 81 216 1.1E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS11840 debe746965caada157fc384747600169 261 SUPERFAMILY SSF55874 87 254 2.88E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11840 debe746965caada157fc384747600169 261 PRINTS PR00344 Bacterial sensor protein C-terminal signature 218 236 2.6E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11840 debe746965caada157fc384747600169 261 PRINTS PR00344 Bacterial sensor protein C-terminal signature 242 255 2.6E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11840 debe746965caada157fc384747600169 261 PRINTS PR00344 Bacterial sensor protein C-terminal signature 201 211 2.6E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11840 debe746965caada157fc384747600169 261 PRINTS PR00344 Bacterial sensor protein C-terminal signature 183 197 2.6E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11840 debe746965caada157fc384747600169 261 SMART SM00387 142 258 5.9E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11840 debe746965caada157fc384747600169 261 SUPERFAMILY SSF47384 24 94 4.71E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11840 debe746965caada157fc384747600169 261 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 142 256 1.4E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11840 debe746965caada157fc384747600169 261 Gene3D G3DSA:1.10.287.130 25 81 1.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11840 debe746965caada157fc384747600169 261 SMART SM00388 30 95 1.2E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11840 debe746965caada157fc384747600169 261 Pfam PF00512 His Kinase A (phospho-acceptor) domain 34 94 4.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11840 debe746965caada157fc384747600169 261 Gene3D G3DSA:3.30.565.10 98 258 4.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 SUPERFAMILY SSF56003 17 204 1.24E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Gene3D G3DSA:3.30.365.10 525 699 1.2E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Gene3D G3DSA:3.30.365.10 17 138 9.7E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 PIRSF PIRSF036389 2 698 5.6E-163 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 562 644 3.8E-14 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 287 419 3.0E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 21 148 1.4E-16 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Gene3D G3DSA:3.90.1170.50 145 214 5.0E-8 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 Gene3D G3DSA:3.30.365.10 342 524 3.0E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00090 8d8def8c808f8cbb519b2e3188bb844f 701 SUPERFAMILY SSF56003 287 699 1.16E-97 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Gene3D G3DSA:3.40.50.300 5 228 8.0E-127 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Gene3D G3DSA:3.40.50.300 356 403 8.0E-127 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SMART SM00957 6 389 1.6E-299 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Pfam PF07517 SecA DEAD-like domain 7 388 3.0E-131 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Pfam PF07516 SecA Wing and Scaffold domain 635 845 8.0E-63 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Pfam PF02810 SEC-C motif 912 930 5.4E-10 T 06-07-2017 IPR004027 SEC-C motif CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF81767 227 355 4.45E-44 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF81886 908 920 5.1E-80 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF81886 637 856 5.1E-80 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Gene3D G3DSA:3.40.50.300 404 635 5.4E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF52540 7 228 2.66E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF52540 355 402 2.66E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SUPERFAMILY SSF52540 403 635 9.12E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 ProSitePatterns PS01312 SecA family signature. 512 527 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Gene3D G3DSA:1.10.3060.10 665 847 4.3E-54 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 460 1.7E-206 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Pfam PF01043 SecA preprotein cross-linking domain 232 345 3.1E-40 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 SMART SM00958 228 345 1.6E-75 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Gene3D G3DSA:3.90.1440.10 231 355 1.9E-46 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 848 20.186 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 363 380 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 400 413 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 170 190 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 101 115 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 117 127 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 63 87 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS10470 d583186d056022bdecd42dc5edf02b43 932 PRINTS PR00906 SecA protein signature 326 348 4.0E-69 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK95_RS02790 2b486bc136aeafe6821dc64be6919c60 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 29 205 3.9E-11 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS02790 2b486bc136aeafe6821dc64be6919c60 244 SUPERFAMILY SSF56784 22 240 1.77E-31 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS02790 2b486bc136aeafe6821dc64be6919c60 244 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 26 205 1.0E-65 T 06-07-2017 IPR010237 Pyrimidine 5-nucleotidase CAK95_RS02790 2b486bc136aeafe6821dc64be6919c60 244 Gene3D G3DSA:3.40.50.1000 25 228 1.6E-25 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS02790 2b486bc136aeafe6821dc64be6919c60 244 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 66 205 8.7E-11 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 SUPERFAMILY SSF51905 6 170 1.7E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 SUPERFAMILY SSF51905 268 356 1.7E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 6.8E-20 T 06-07-2017 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 6.8E-20 T 06-07-2017 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 6.8E-20 T 06-07-2017 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 6.8E-20 T 06-07-2017 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 SUPERFAMILY SSF54373 175 274 4.12E-18 T 06-07-2017 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 Gene3D G3DSA:3.50.50.60 7 175 4.8E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 Gene3D G3DSA:3.50.50.60 268 349 4.8E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27615 819c5cbb47c54b929a958869950f75cd 395 Pfam PF01494 FAD binding domain 8 342 9.8E-27 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS05490 fb983d568551d4f0d0ae7fbc19b87633 202 Gene3D G3DSA:2.60.370.10 61 190 1.6E-46 T 06-07-2017 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05490 fb983d568551d4f0d0ae7fbc19b87633 202 Hamap MF_00155 Cytochrome c oxidase assembly protein CtaG [ctaG]. 1 187 39.804 T 06-07-2017 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 CAK95_RS05490 fb983d568551d4f0d0ae7fbc19b87633 202 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 36 180 6.8E-50 T 06-07-2017 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 CAK95_RS05490 fb983d568551d4f0d0ae7fbc19b87633 202 SUPERFAMILY SSF110111 61 184 1.7E-43 T 06-07-2017 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05490 fb983d568551d4f0d0ae7fbc19b87633 202 PIRSF PIRSF005413 2 197 4.1E-64 T 06-07-2017 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 Gene3D G3DSA:3.40.50.720 3 245 3.5E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 0.0073 T 06-07-2017 CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 243 3.3E-59 T 06-07-2017 CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 SUPERFAMILY SSF51735 7 245 3.18E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01485 869fe11c41d9d92c9bd2dd5c2b597a9b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 1.0E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 1.0E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 46 1.0E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 SMART SM00418 29 107 3.6E-27 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 Gene3D G3DSA:1.10.10.10 17 111 7.1E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 Pfam PF01022 Bacterial regulatory protein, arsR family 37 82 2.2E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS23425 b915c589efccc1586030b3761ebd3822 115 SUPERFAMILY SSF46785 25 110 1.04E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 SUPERFAMILY SSF53850 92 296 2.17E-43 T 06-07-2017 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 SUPERFAMILY SSF46785 7 86 1.05E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 65 1.4E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Pfam PF03466 LysR substrate binding domain 97 297 1.9E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Gene3D G3DSA:3.40.190.10 174 269 2.5E-30 T 06-07-2017 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Gene3D G3DSA:1.10.10.10 4 87 6.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Gene3D G3DSA:3.40.190.10 274 302 2.5E-27 T 06-07-2017 CAK95_RS23095 5ace304c0a13cd9ecc45f954cc2aaba5 325 Gene3D G3DSA:3.40.190.10 92 173 2.5E-27 T 06-07-2017 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 SUPERFAMILY SSF53659 5 740 0.0 T 06-07-2017 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 PIRSF PIRSF009407 1 740 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 6 737 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 Gene3D G3DSA:3.40.718.10 538 645 8.8E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 Gene3D G3DSA:3.40.718.10 339 362 8.8E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 Gene3D G3DSA:3.40.718.10 173 287 8.8E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26555 a260ccb6139ec045af68ef3488c55be4 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 4 740 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 SUPERFAMILY SSF53850 122 324 3.1E-26 T 06-07-2017 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 SUPERFAMILY SSF46785 32 134 1.07E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 Gene3D G3DSA:1.10.10.10 32 117 4.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 38 93 2.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 Pfam PF03466 LysR substrate binding domain 119 323 1.1E-27 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 5.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 70 81 5.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 70 5.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 Gene3D G3DSA:3.40.190.10 206 291 8.4E-14 T 06-07-2017 CAK95_RS19580 b9fbc3bcc30a31a6f1ad30ac8143507e 336 Gene3D G3DSA:3.40.190.10 119 205 1.1E-16 T 06-07-2017 CAK95_RS05150 41c50776ad68b5562afce91bf0067a54 298 Pfam PF09955 Predicted integral membrane protein (DUF2189) 72 198 4.0E-41 T 06-07-2017 IPR018692 Predicted integral membrane protein DUF2189 CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 Gene3D G3DSA:3.40.30.10 14 94 9.4E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 SUPERFAMILY SSF52833 9 87 3.48E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 Pfam PF13417 Glutathione S-transferase, N-terminal domain 16 82 3.5E-7 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 SUPERFAMILY SSF47616 85 203 3.27E-18 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 Gene3D G3DSA:1.20.1050.10 95 208 3.2E-40 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS25185 b9ff3a31735866e52df15448ea1f50a6 218 Pfam PF13410 Glutathione S-transferase, C-terminal domain 130 203 7.6E-8 T 06-07-2017 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 Pfam PF00171 Aldehyde dehydrogenase family 23 488 2.7E-161 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 Gene3D G3DSA:3.40.309.10 273 461 3.7E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 Gene3D G3DSA:3.40.605.10 13 272 1.5E-92 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS12475 81c39b13daa3bceaa10ee6f4ccd52319 492 SUPERFAMILY SSF53720 9 491 8.51E-153 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS00545 28f3306b5c87015a6c14e55d57d59026 739 SUPERFAMILY SSF53335 468 659 1.14E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00545 28f3306b5c87015a6c14e55d57d59026 739 Gene3D G3DSA:3.40.50.150 469 729 5.0E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00545 28f3306b5c87015a6c14e55d57d59026 739 SUPERFAMILY SSF103473 9 363 4.32E-7 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 4 526 7.7E-207 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Gene3D G3DSA:3.30.70.260 448 524 1.7E-16 T 06-07-2017 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 SUPERFAMILY SSF143548 321 450 3.4E-38 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Gene3D G3DSA:3.40.50.720 2 109 1.9E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Gene3D G3DSA:3.40.50.720 110 284 6.1E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Pfam PF01842 ACT domain 456 518 1.0E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 315 1.7E-37 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 SUPERFAMILY SSF51735 100 284 8.39E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Gene3D G3DSA:3.30.1330.90 320 447 1.2E-47 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 283 1.7E-62 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 SUPERFAMILY SSF52283 3 129 3.21E-38 T 06-07-2017 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 SUPERFAMILY SSF55021 445 525 2.46E-15 T 06-07-2017 CAK95_RS28135 1d401b49dacf66274d4119ae0c1848af 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 Gene3D G3DSA:3.40.50.300 5 255 9.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 Gene3D G3DSA:2.40.50.140 297 358 4.2E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 Pfam PF08402 TOBE domain 294 366 2.9E-6 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 SUPERFAMILY SSF52540 4 259 4.82E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 Pfam PF00005 ABC transporter 20 178 6.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 SUPERFAMILY SSF50331 254 374 1.42E-15 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS00975 230c0d5c91645583ec6317e0c04ac928 383 SMART SM00382 28 228 2.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10930 526f34310979cb42332874349b79d7dd 212 Gene3D G3DSA:3.40.50.300 2 203 1.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10930 526f34310979cb42332874349b79d7dd 212 Pfam PF02224 Cytidylate kinase 3 202 8.1E-55 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK95_RS10930 526f34310979cb42332874349b79d7dd 212 SUPERFAMILY SSF52540 2 204 4.21E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10930 526f34310979cb42332874349b79d7dd 212 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 200 5.1E-51 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK95_RS10930 526f34310979cb42332874349b79d7dd 212 Hamap MF_00238 Cytidylate kinase [cmk]. 1 206 30.376 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 Gene3D G3DSA:1.20.1080.10 1 224 3.4E-60 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 ProSitePatterns PS00221 MIP family signature. 61 69 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 Pfam PF00230 Major intrinsic protein 2 224 6.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 SUPERFAMILY SSF81338 1 224 6.93E-56 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 165 187 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 43 67 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 80 99 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 135 153 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS20205 a84ddea02503918199b0917a40dadc1a 234 PRINTS PR00783 Major intrinsic protein family signature 207 227 1.1E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 SMART SM00382 36 219 6.5E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 42 356 2.4E-108 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 Pfam PF08402 TOBE domain 288 363 6.9E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 Gene3D G3DSA:3.40.50.300 9 242 3.4E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 Pfam PF00005 ABC transporter 29 169 2.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 SUPERFAMILY SSF50331 249 366 4.82E-11 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS16870 5ce7cebc0d6c71c2b53f1351e79922d7 368 SUPERFAMILY SSF52540 12 248 4.9E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 Gene3D G3DSA:1.10.10.10 3 82 2.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 Gene3D G3DSA:3.40.190.10 168 239 6.3E-9 T 06-07-2017 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 SUPERFAMILY SSF53850 92 257 9.93E-27 T 06-07-2017 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 Pfam PF03466 LysR substrate binding domain 91 239 3.9E-24 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 SUPERFAMILY SSF46785 6 112 4.48E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 Gene3D G3DSA:3.40.190.10 93 167 2.7E-13 T 06-07-2017 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04710 e21ad4fbb59b761e0e6c14327ef616d7 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10585 47dbc496e08a1576d75041ba2c5caa3c 332 Pfam PF12710 haloacid dehalogenase-like hydrolase 63 268 2.4E-23 T 06-07-2017 CAK95_RS10585 47dbc496e08a1576d75041ba2c5caa3c 332 SUPERFAMILY SSF56784 60 309 1.23E-24 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS10585 47dbc496e08a1576d75041ba2c5caa3c 332 Gene3D G3DSA:3.40.50.1000 159 299 3.6E-14 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS10585 47dbc496e08a1576d75041ba2c5caa3c 332 Gene3D G3DSA:3.40.50.1000 61 76 3.6E-14 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 38 440 4.5E-160 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 Gene3D G3DSA:3.40.640.10 87 348 4.1E-89 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 Pfam PF00202 Aminotransferase class-III 44 440 7.8E-114 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 SUPERFAMILY SSF53383 35 442 1.58E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 Gene3D G3DSA:3.90.1150.10 351 442 2.5E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS12825 23de6c501f6e1e8fd2cf2629b5f8b888 444 Gene3D G3DSA:3.90.1150.10 35 86 2.5E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 210 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 PIRSF PIRSF000105 2 293 3.9E-81 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 184 1.8E-59 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 Gene3D G3DSA:3.40.50.720 3 190 1.2E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 SUPERFAMILY SSF48179 187 289 9.35E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 284 1.8E-33 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 Gene3D G3DSA:1.10.1040.10 191 285 6.9E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS11950 4fcf90f2372ddb32a57126b8274ac1de 293 SUPERFAMILY SSF51735 4 187 7.03E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07335 193c735e05cd091ce2e7a420003d395d 160 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 28.112 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS07335 193c735e05cd091ce2e7a420003d395d 160 PIRSF PIRSF004505 1 159 1.3E-46 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS07335 193c735e05cd091ce2e7a420003d395d 160 Gene3D G3DSA:3.40.1280.10 1 159 1.8E-54 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS07335 193c735e05cd091ce2e7a420003d395d 160 SUPERFAMILY SSF75217 1 157 1.83E-44 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS07335 193c735e05cd091ce2e7a420003d395d 160 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 9.1E-47 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Gene3D G3DSA:3.40.50.980 3 160 4.9E-38 T 06-07-2017 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Gene3D G3DSA:3.30.300.30 403 496 1.9E-27 T 06-07-2017 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Gene3D G3DSA:3.40.50.980 161 310 1.9E-26 T 06-07-2017 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 488 8.8E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 SUPERFAMILY SSF56801 2 500 2.88E-129 T 06-07-2017 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Pfam PF00501 AMP-binding enzyme 10 408 7.0E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS08370 0a9ae06ca28467f7cf0b47fa1ced785e 506 Gene3D G3DSA:2.30.38.10 326 398 9.9E-23 T 06-07-2017 CAK95_RS23830 a5ef71352e28a64178232e7597005c6e 232 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 204 1.9E-40 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CAK95_RS23830 a5ef71352e28a64178232e7597005c6e 232 SUPERFAMILY SSF56784 3 207 6.81E-39 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS23830 a5ef71352e28a64178232e7597005c6e 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 106 196 7.7E-8 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS23830 a5ef71352e28a64178232e7597005c6e 232 Gene3D G3DSA:3.40.50.1000 2 224 7.6E-29 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS23830 a5ef71352e28a64178232e7597005c6e 232 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 6 189 1.2E-17 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 SMART SM00471 64 225 2.1E-9 T 06-07-2017 IPR003607 HD/PDEase domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Pfam PF13286 Phosphohydrolase-associated domain 302 392 2.7E-23 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 394 5.8E-97 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Pfam PF01966 HD domain 68 182 7.2E-13 T 06-07-2017 IPR006674 HD domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 SUPERFAMILY SSF109604 196 397 8.05E-89 T 06-07-2017 CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 SUPERFAMILY SSF109604 19 164 8.05E-89 T 06-07-2017 CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Gene3D G3DSA:1.10.3210.10 291 397 6.8E-77 T 06-07-2017 IPR006674 HD domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Gene3D G3DSA:1.10.3210.10 197 234 6.8E-77 T 06-07-2017 IPR006674 HD domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Gene3D G3DSA:1.10.3210.10 29 164 6.8E-77 T 06-07-2017 IPR006674 HD domain CAK95_RS23950 d942bc1c43d57a1dcf93210b2457c8f7 401 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 8 394 37.985 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 CAK95_RS17005 7487a37624e48a2688541f55e6293e90 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 291 8.5E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17005 7487a37624e48a2688541f55e6293e90 296 SUPERFAMILY SSF161098 100 281 3.01E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17005 7487a37624e48a2688541f55e6293e90 296 Gene3D G3DSA:1.10.3720.10 98 285 2.7E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17005 7487a37624e48a2688541f55e6293e90 296 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 84 285 2.9E-96 T 06-07-2017 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CAK95_RS03260 9f432f7f9e8130523cecf27d97eb6a2b 251 Gene3D G3DSA:3.40.50.300 5 242 2.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03260 9f432f7f9e8130523cecf27d97eb6a2b 251 SUPERFAMILY SSF52540 6 246 1.25E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03260 9f432f7f9e8130523cecf27d97eb6a2b 251 Pfam PF00005 ABC transporter 22 176 4.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS03260 9f432f7f9e8130523cecf27d97eb6a2b 251 SMART SM00382 30 224 7.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 SUPERFAMILY SSF47384 326 402 5.89E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 Gene3D G3DSA:3.30.565.10 405 557 7.0E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 555 1.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 536 1.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 1.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 517 1.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 Pfam PF05231 MASE1 31 306 6.7E-18 T 06-07-2017 IPR007895 MASE1 CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 SMART SM00387 446 558 2.3E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 557 4.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS07085 4aa6b7705a93ab8109557d1871fee269 563 SUPERFAMILY SSF55874 397 557 7.2E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15365 ea6ecb3255053106d87fde2a0e66a3de 241 Pfam PF13860 FlgD Ig-like domain 111 177 1.1E-12 T 06-07-2017 IPR025965 FlgD Ig-like domain CAK95_RS15365 ea6ecb3255053106d87fde2a0e66a3de 241 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 77 3.1E-17 T 06-07-2017 IPR005648 Flagellar hook capping protein CAK95_RS15365 ea6ecb3255053106d87fde2a0e66a3de 241 Pfam PF13861 FlgD Tudor-like domain 87 217 5.6E-12 T 06-07-2017 IPR025963 FlgD Tudor-like domain CAK95_RS02895 268d47b4232f71e972a649bbd0e5f3bf 338 Gene3D G3DSA:3.40.50.1980 176 304 3.2E-26 T 06-07-2017 CAK95_RS02895 268d47b4232f71e972a649bbd0e5f3bf 338 SUPERFAMILY SSF53807 25 334 1.77E-50 T 06-07-2017 CAK95_RS02895 268d47b4232f71e972a649bbd0e5f3bf 338 Gene3D G3DSA:3.40.50.1980 22 154 4.5E-11 T 06-07-2017 CAK95_RS02895 268d47b4232f71e972a649bbd0e5f3bf 338 Pfam PF01497 Periplasmic binding protein 89 274 2.7E-20 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK95_RS28560 90ea10faba4fc2c8e75bd40655156893 388 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 111 382 1.7E-63 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28560 90ea10faba4fc2c8e75bd40655156893 388 SUPERFAMILY SSF53850 179 339 1.99E-7 T 06-07-2017 CAK95_RS03340 1482dfcc8e027279244a850aa2cc1557 392 Gene3D G3DSA:3.40.50.720 193 353 9.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03340 1482dfcc8e027279244a850aa2cc1557 392 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 153 374 1.5E-29 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS03340 1482dfcc8e027279244a850aa2cc1557 392 Gene3D G3DSA:3.30.1780.10 14 192 1.0E-17 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAK95_RS03340 1482dfcc8e027279244a850aa2cc1557 392 SUPERFAMILY SSF51735 130 383 4.32E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20490 33173c1140de9f5eff2557232f324406 196 SMART SM00100 51 167 6.3E-6 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS20490 33173c1140de9f5eff2557232f324406 196 SUPERFAMILY SSF51206 63 177 2.09E-22 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS20490 33173c1140de9f5eff2557232f324406 196 Pfam PF00027 Cyclic nucleotide-binding domain 75 154 1.3E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS20490 33173c1140de9f5eff2557232f324406 196 Gene3D G3DSA:2.60.120.10 68 175 4.6E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20490 33173c1140de9f5eff2557232f324406 196 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 116 134 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 Gene3D G3DSA:3.40.710.10 309 674 1.4E-114 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 SUPERFAMILY SSF53955 123 333 9.28E-73 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 Pfam PF00905 Penicillin binding protein transpeptidase domain 395 656 2.7E-33 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 SUPERFAMILY SSF56601 337 670 4.86E-119 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 SUPERFAMILY SSF56601 288 310 4.86E-119 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 Gene3D G3DSA:1.10.3810.10 145 308 9.5E-72 T 06-07-2017 CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 Pfam PF00912 Transglycosylase 142 306 6.3E-65 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK95_RS06305 8c9af3d1cf40aa46fb9268836376ab9e 730 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 145 662 3.8E-190 T 06-07-2017 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 SUPERFAMILY SSF46785 3 84 1.72E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Pfam PF03466 LysR substrate binding domain 95 299 3.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Gene3D G3DSA:3.40.190.10 174 271 2.4E-20 T 06-07-2017 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 68 4.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 SUPERFAMILY SSF53850 91 300 2.53E-42 T 06-07-2017 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Gene3D G3DSA:3.40.190.10 91 173 5.1E-27 T 06-07-2017 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Gene3D G3DSA:3.40.190.10 276 303 5.1E-27 T 06-07-2017 CAK95_RS22280 3e7a1b32d2e2903ec5ffe05bc869b079 304 Gene3D G3DSA:1.10.10.10 2 85 7.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12680 93c1f6181357d647f6179442ca693de9 162 Gene3D G3DSA:2.60.120.10 28 141 1.3E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS12680 93c1f6181357d647f6179442ca693de9 162 Pfam PF07883 Cupin domain 75 141 6.9E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS12680 93c1f6181357d647f6179442ca693de9 162 SUPERFAMILY SSF51182 58 151 2.82E-23 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 SUPERFAMILY SSF54665 5 155 1.7E-34 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 25 133 1.1E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 628 777 3.4E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 369 456 3.4E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.90.1170.50 5 122 7.8E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 178 282 3.3E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 149 713 1.8E-150 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 457 606 8.7E-40 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 SUPERFAMILY SSF56003 125 776 3.01E-181 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 SMART SM01008 24 133 1.3E-31 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 285 362 1.2E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00425 130692784fdc2cfaa41ae871c3e98644 784 Gene3D G3DSA:3.30.365.10 123 177 1.2E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21510 62820a577a3cdfd8d0b94ea3874eafd2 225 Gene3D G3DSA:3.40.50.1000 67 217 3.2E-44 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21510 62820a577a3cdfd8d0b94ea3874eafd2 225 SUPERFAMILY SSF56784 1 217 6.14E-60 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21510 62820a577a3cdfd8d0b94ea3874eafd2 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 180 1.9E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21510 62820a577a3cdfd8d0b94ea3874eafd2 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 186 1.7E-34 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21510 62820a577a3cdfd8d0b94ea3874eafd2 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 186 7.1E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 289 364 1.8E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 126 179 1.8E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 367 463 1.1E-51 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 605 755 1.1E-51 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 SUPERFAMILY SSF54665 5 156 3.79E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 690 7.7E-149 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 SMART SM01008 22 137 1.1E-47 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 238 251 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 180 286 3.1E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.90.1170.50 5 125 7.0E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Gene3D G3DSA:3.30.365.10 464 578 8.5E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 SUPERFAMILY SSF56003 130 756 4.19E-167 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14280 74b4405f45e9677a410527c1f990adda 763 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 137 1.3E-24 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 SUPERFAMILY SSF52540 41 290 7.88E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 269 353 8.8E-23 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 615 702 5.9E-25 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 ProSitePatterns PS00211 ABC transporters family signature. 192 206 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Pfam PF00005 ABC transporter 413 564 8.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Pfam PF00005 ABC transporter 62 219 4.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 SMART SM00382 421 614 1.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 SMART SM00382 70 269 1.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Gene3D G3DSA:3.40.50.300 385 638 9.2E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Gene3D G3DSA:3.40.50.300 40 293 1.7E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 ProSitePatterns PS00211 ABC transporters family signature. 537 551 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 616 683 8.0E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 271 336 3.7E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS11470 b6f5f9c52a0ba9847a8b210a35fe5765 704 SUPERFAMILY SSF52540 386 635 1.39E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 353 444 3.2E-82 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 611 766 3.2E-82 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 131 8.6E-29 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 169 275 2.1E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 277 352 5.4E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 140 168 5.4E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.90.1170.50 14 131 5.7E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 149 696 1.7E-201 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 SMART SM01008 26 133 2.6E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 SUPERFAMILY SSF56003 137 767 3.93E-202 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 SUPERFAMILY SSF54665 13 134 6.67E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 13 767 0.0 T 06-07-2017 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 CAK95_RS10030 6c45313baac702d673391b3a654d1632 774 Gene3D G3DSA:3.30.365.10 445 601 2.2E-53 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR01900 YidC translocation/secretion protein signature 522 537 2.6E-22 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR01900 YidC translocation/secretion protein signature 368 384 2.6E-22 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR01900 YidC translocation/secretion protein signature 541 565 2.6E-22 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 Pfam PF02096 60Kd inner membrane protein 383 586 6.0E-59 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 381 7.1E-98 T 06-07-2017 IPR028053 Membrane insertase YidC, N-terminal CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR00701 60kDa inner membrane protein signature 272 287 1.9E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR00701 60kDa inner membrane protein signature 444 467 1.9E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR00701 60kDa inner membrane protein signature 3 24 1.9E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 PRINTS PR00701 60kDa inner membrane protein signature 353 373 1.9E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 382 586 3.6E-68 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 Pfam PF14849 YidC periplasmic domain 91 372 8.9E-86 T 06-07-2017 IPR028053 Membrane insertase YidC, N-terminal CAK95_RS12190 4922bcd4c5a8dc5bf913f12d24bfdaf4 612 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 588 23.279 T 06-07-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 CAK95_RS13225 fd87c9d07992c0bf3df085d84cb24529 469 TIGRFAM TIGR03173 pbuX: xanthine permease 24 447 3.6E-158 T 06-07-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CAK95_RS13225 fd87c9d07992c0bf3df085d84cb24529 469 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 444 6.0E-115 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CAK95_RS13225 fd87c9d07992c0bf3df085d84cb24529 469 Pfam PF00860 Permease family 21 412 8.3E-98 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK95_RS24895 22e9528a8459f44a0b1e0b902ea955c1 340 Gene3D G3DSA:3.40.190.10 148 252 2.9E-4 T 06-07-2017 CAK95_RS24895 22e9528a8459f44a0b1e0b902ea955c1 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 333 1.7E-49 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS24895 22e9528a8459f44a0b1e0b902ea955c1 340 SUPERFAMILY SSF53850 126 299 7.76E-9 T 06-07-2017 CAK95_RS24895 22e9528a8459f44a0b1e0b902ea955c1 340 PIRSF PIRSF017082 9 338 6.1E-63 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 SUPERFAMILY SSF56059 1 393 3.3E-148 T 06-07-2017 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 530 885 8.5E-89 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:3.30.470.20 247 356 1.3E-38 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:1.20.80.30 115 201 7.1E-36 T 06-07-2017 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:1.10.189.10 357 414 9.3E-31 T 06-07-2017 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 887 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 PIRSF PIRSF000853 1 895 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 777 795 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Pfam PF00391 PEP-utilising enzyme, mobile domain 435 516 2.4E-28 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:3.30.1490.20 203 246 1.0E-57 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:3.30.1490.20 3 114 1.0E-57 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 463 474 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:3.20.20.60 545 887 1.0E-135 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Gene3D G3DSA:3.50.30.10 415 519 2.4E-43 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 370 2.0E-64 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 SUPERFAMILY SSF51621 524 887 4.32E-127 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS00505 b90e5ff8c0065906c7b3b64329eef276 895 SUPERFAMILY SSF52009 402 525 2.88E-39 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82866 288 488 5.23E-42 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:3.30.2090.10 699 776 1.9E-6 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82714 699 777 2.88E-6 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82714 183 263 6.02E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:1.10.3850.10 787 1015 1.5E-50 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82693 266 322 8.11E-16 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82693 138 180 8.11E-16 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:3.30.70.1430 41 141 6.2E-21 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82866 784 1017 2.49E-38 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82693 551 647 2.82E-6 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:3.30.70.1430 553 645 7.5E-5 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 7.9E-28 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 SUPERFAMILY SSF82693 41 134 1.75E-20 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Pfam PF00873 AcrB/AcrD/AcrF family 5 1014 4.6E-171 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:1.20.1640.10 283 492 2.9E-50 T 06-07-2017 CAK95_RS10045 1877d800e3a0d0a2626a8cca617fc7ca 1041 Gene3D G3DSA:3.30.2090.10 182 263 1.9E-10 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS27690 b35d442b032d4e97162c017c74dbd293 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 9.2E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27690 b35d442b032d4e97162c017c74dbd293 327 SUPERFAMILY SSF53850 114 296 1.57E-15 T 06-07-2017 CAK95_RS27690 b35d442b032d4e97162c017c74dbd293 327 PIRSF PIRSF017082 1 327 2.9E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27690 b35d442b032d4e97162c017c74dbd293 327 Gene3D G3DSA:3.40.190.10 128 232 1.4E-4 T 06-07-2017 CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 Gene3D G3DSA:1.10.10.10 5 86 1.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 Gene3D G3DSA:3.40.190.10 178 245 3.8E-8 T 06-07-2017 CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 Pfam PF03466 LysR substrate binding domain 90 285 4.1E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 SUPERFAMILY SSF53850 91 291 3.44E-35 T 06-07-2017 CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.7E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 SUPERFAMILY SSF46785 5 113 5.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15315 db18fe4fd1dcd044b6ddc0c8803e75bf 297 Gene3D G3DSA:3.40.190.10 93 177 1.5E-22 T 06-07-2017 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Pfam PF00501 AMP-binding enzyme 11 409 1.2E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Gene3D G3DSA:3.30.300.30 404 500 1.2E-29 T 06-07-2017 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 SUPERFAMILY SSF56801 6 503 7.72E-120 T 06-07-2017 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 492 9.7E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Gene3D G3DSA:3.40.50.980 8 166 3.3E-28 T 06-07-2017 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Gene3D G3DSA:3.40.50.980 167 316 8.0E-32 T 06-07-2017 CAK95_RS25425 dae121486bc99df6dd062330f39d66ad 516 Gene3D G3DSA:2.30.38.10 320 400 8.7E-15 T 06-07-2017 CAK95_RS23875 a94f4a4faee8603082ca3ad782733825 114 SMART SM01323 16 99 1.9E-41 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK95_RS23875 a94f4a4faee8603082ca3ad782733825 114 Pfam PF02699 Preprotein translocase subunit 20 96 5.9E-28 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK95_RS23875 a94f4a4faee8603082ca3ad782733825 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 18 38 6.3E-18 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK95_RS23875 a94f4a4faee8603082ca3ad782733825 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 56 74 6.3E-18 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK95_RS23875 a94f4a4faee8603082ca3ad782733825 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 17 98 3.9E-28 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 317 2.4E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SMART SM00388 250 320 2.2E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Gene3D G3DSA:1.10.287.130 249 316 8.4E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SMART SM00091 114 181 9.2E-6 T 06-07-2017 IPR000014 PAS domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SUPERFAMILY SSF55874 325 470 1.31E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SUPERFAMILY SSF55785 134 235 4.66E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SUPERFAMILY SSF47384 243 317 1.16E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Pfam PF08448 PAS fold 135 228 6.8E-12 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SMART SM00387 362 473 5.2E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Gene3D G3DSA:3.30.565.10 319 471 2.8E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Gene3D G3DSA:3.30.450.20 114 226 7.5E-20 T 06-07-2017 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 234 2.0E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 7.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 7.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 7.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 7.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 471 2.0E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS15440 49cea9ffe5fd1feeae21ffb1be8bd2fb 485 SMART SM00086 186 228 0.0018 T 06-07-2017 IPR001610 PAC motif CAK95_RS23060 98ac3b6eabe7bb5643e50ad969470ebf 764 Pfam PF13567 Domain of unknown function (DUF4131) 69 232 1.4E-14 T 06-07-2017 IPR025405 Domain of unknown function DUF4131 CAK95_RS23060 98ac3b6eabe7bb5643e50ad969470ebf 764 Pfam PF03772 Competence protein 279 564 3.7E-61 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAK95_RS23060 98ac3b6eabe7bb5643e50ad969470ebf 764 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 300 496 1.0E-20 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAK95_RS13825 5170950b375e7c2cc1578ba81f4ebf74 173 SUPERFAMILY SSF51182 8 135 5.24E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS13825 5170950b375e7c2cc1578ba81f4ebf74 173 Gene3D G3DSA:2.60.120.10 59 134 2.5E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS13825 5170950b375e7c2cc1578ba81f4ebf74 173 Pfam PF07883 Cupin domain 67 118 2.9E-7 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS13825 5170950b375e7c2cc1578ba81f4ebf74 173 PIRSF PIRSF019307 2 173 2.0E-67 T 06-07-2017 IPR014500 Uncharacterised conserved protein UCP019307, cupin-type CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82693 563 653 8.11E-13 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Pfam PF00873 AcrB/AcrD/AcrF family 3 1018 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82866 796 1020 2.22E-44 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82693 136 182 5.49E-21 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82693 268 324 5.49E-21 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82866 291 490 5.49E-49 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:3.30.70.1430 41 141 3.4E-25 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82714 713 798 2.09E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:3.30.2090.10 713 798 5.6E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82714 184 266 3.27E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 SUPERFAMILY SSF82693 41 125 8.89E-20 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 617 631 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:3.30.2090.10 184 268 3.0E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:1.20.1640.10 285 498 6.3E-59 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:3.30.70.1430 566 633 7.6E-9 T 06-07-2017 CAK95_RS16045 0f821fe229c2b8bb1adec834e1bc6c70 1044 Gene3D G3DSA:1.10.3850.10 806 1020 9.0E-54 T 06-07-2017 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 311 2.2E-121 T 06-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Gene3D G3DSA:3.30.470.20 192 297 2.3E-41 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 120 1.2E-42 T 06-07-2017 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 295 4.0E-68 T 06-07-2017 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Gene3D G3DSA:3.30.1490.20 137 191 6.7E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 SUPERFAMILY SSF52440 3 122 2.04E-42 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 SUPERFAMILY SSF56059 124 310 4.42E-53 T 06-07-2017 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Hamap MF_00162 Glutathione synthetase [gshB]. 1 315 153.099 T 06-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAK95_RS08840 1212464379ff94e39594f18989152fe0 315 Gene3D G3DSA:3.40.50.20 3 129 8.6E-52 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 Gene3D G3DSA:3.30.390.10 1 128 4.0E-26 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 SUPERFAMILY SSF54826 4 127 1.03E-18 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 SUPERFAMILY SSF51604 113 349 7.86E-49 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 Gene3D G3DSA:3.20.20.120 129 349 4.3E-49 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 Pfam PF13378 Enolase C-terminal domain-like 149 349 3.8E-42 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 SMART SM00922 145 240 1.1E-14 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS02075 b59f7d5ce8aebfd0acf03b2405e76451 351 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 29 125 6.7E-10 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 188 236 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 117 237 2.9E-16 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 Gene3D G3DSA:2.60.40.420 108 264 6.1E-40 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 SUPERFAMILY SSF81464 23 105 3.43E-5 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 SUPERFAMILY SSF49503 111 256 3.66E-42 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS05175 b882055c682f43cc5281b08c33fb9766 277 Gene3D G3DSA:1.10.287.90 35 84 2.7E-5 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS01625 62ac8f211371d3b5d275d28a650c72f4 205 SUPERFAMILY SSF56925 39 205 6.54E-32 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS01625 62ac8f211371d3b5d275d28a650c72f4 205 Pfam PF13505 Outer membrane protein beta-barrel domain 14 205 4.5E-27 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS01625 62ac8f211371d3b5d275d28a650c72f4 205 Gene3D G3DSA:2.40.160.20 13 205 2.6E-36 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 Pfam PF00294 pfkB family carbohydrate kinase 12 295 1.8E-46 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 309 3.0E-91 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 Gene3D G3DSA:3.40.1190.20 35 311 4.6E-73 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 SUPERFAMILY SSF53613 4 295 9.82E-67 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS03805 dd789cab8ed7738a9aa69a72204b259e 312 PIRSF PIRSF000535 1 312 8.5E-89 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 SMART SM00347 48 151 1.1E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 Gene3D G3DSA:1.10.10.10 14 165 2.8E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 Pfam PF12802 MarR family 60 115 4.1E-8 T 06-07-2017 CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 SUPERFAMILY SSF46785 17 164 6.52E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 9.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 9.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS08320 7b462afcb1c7071077a8e5e4f8e8a88c 195 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 9.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82714 183 262 7.32E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:1.10.3850.10 273 492 1.5E-58 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:1.10.3850.10 803 1015 6.9E-47 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:3.30.70.1430 559 650 2.2E-11 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82866 824 1016 3.14E-38 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 667 708 2.22E-12 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 797 841 2.22E-12 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:3.30.70.1430 40 142 5.2E-29 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:3.30.2090.10 709 793 5.4E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:3.30.2090.10 182 262 1.6E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 555 656 2.96E-14 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Pfam PF00873 AcrB/AcrD/AcrF family 5 1015 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 Gene3D G3DSA:3.30.70.1440 673 707 3.6E-7 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 138 182 4.34E-22 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 268 324 4.34E-22 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 612 626 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.1E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82693 40 130 2.88E-23 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82866 290 491 1.44E-48 T 06-07-2017 CAK95_RS19575 d8d9d01bfcd5f667349a58aa7282f688 1016 SUPERFAMILY SSF82714 709 793 9.94E-16 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 255 274 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 349 367 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 40 65 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 373 391 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 419 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 226 242 1.2E-34 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 18 519 5.8E-111 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 SUPERFAMILY SSF56235 3 527 2.32E-164 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS10325 284e6066b172a739d3044832d28fde31 527 Pfam PF01019 Gamma-glutamyltranspeptidase 33 522 4.7E-145 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 22 468 7.8E-150 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 SUPERFAMILY SSF53271 256 476 1.52E-75 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 Pfam PF13537 Glutamine amidotransferase domain 103 219 6.5E-17 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 Pfam PF00156 Phosphoribosyl transferase domain 282 392 1.2E-9 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 21 469 45.934 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 Gene3D G3DSA:3.60.20.10 22 264 1.2E-59 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 PIRSF PIRSF000485 18 483 6.2E-164 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 SUPERFAMILY SSF56235 22 248 1.12E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS25965 c7b57a5cde09ec6e07ff15291cae0c04 491 Gene3D G3DSA:3.40.50.2020 277 444 1.6E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 Pfam PF01321 Creatinase/Prolidase N-terminal domain 98 247 2.2E-4 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 Gene3D G3DSA:3.40.350.10 88 244 1.1E-10 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 Pfam PF00557 Metallopeptidase family M24 257 447 1.7E-22 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 SUPERFAMILY SSF55920 248 475 8.37E-37 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 Gene3D G3DSA:3.90.230.10 249 474 8.7E-31 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS10185 ce81d2a401c0a1eb981e0160aabc754d 476 SUPERFAMILY SSF53092 86 245 7.32E-11 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAK95_RS04530 71d51ac5a03be910b8b00e2de76e3aa1 468 Gene3D G3DSA:3.90.1150.10 311 440 9.4E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS04530 71d51ac5a03be910b8b00e2de76e3aa1 468 Gene3D G3DSA:3.40.640.10 98 310 1.6E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS04530 71d51ac5a03be910b8b00e2de76e3aa1 468 SUPERFAMILY SSF53383 41 439 5.84E-112 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS04530 71d51ac5a03be910b8b00e2de76e3aa1 468 Pfam PF00202 Aminotransferase class-III 46 437 2.3E-96 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS04530 71d51ac5a03be910b8b00e2de76e3aa1 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 Pfam PF05194 UreE urease accessory protein, C-terminal domain 75 147 1.8E-15 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 Pfam PF02814 UreE urease accessory protein, N-terminal domain 16 68 3.8E-9 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 Gene3D G3DSA:2.60.260.20 18 72 8.9E-9 T 06-07-2017 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 SUPERFAMILY SSF69737 74 141 2.09E-14 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 SMART SM00988 5 68 2.1E-5 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 PIRSF PIRSF036402 2 148 2.7E-28 T 06-07-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 Gene3D G3DSA:3.30.70.790 75 145 1.4E-17 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 SUPERFAMILY SSF69287 17 74 2.35E-9 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAK95_RS20085 bcf111455f07694c2d59af29bbd84694 148 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 142 18.346 T 06-07-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 PIRSF PIRSF000103 1 296 2.6E-67 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 Gene3D G3DSA:3.40.50.720 2 165 8.9E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24140 8916612eac36db9c99982de88579710d 299 SUPERFAMILY SSF48179 167 291 7.14E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 Gene3D G3DSA:1.10.1040.10 168 292 4.7E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 SUPERFAMILY SSF51735 3 166 7.62E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24140 8916612eac36db9c99982de88579710d 299 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 8.5E-36 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS24140 8916612eac36db9c99982de88579710d 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 164 3.3E-45 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 SMART SM00732 19 119 2.1E-33 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 Gene3D G3DSA:3.30.420.140 19 157 7.4E-48 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 SUPERFAMILY SSF53098 19 153 5.92E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 19 154 23.552 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 22 151 5.3E-34 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK95_RS22105 d1096187accb0a87f1e2eecab89b7eba 162 Pfam PF03652 Holliday junction resolvase 21 151 3.1E-40 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK95_RS27390 23fe043fbb778f84672e48860f44f420 359 Pfam PF00296 Luciferase-like monooxygenase 11 328 9.4E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS27390 23fe043fbb778f84672e48860f44f420 359 Gene3D G3DSA:3.20.20.30 7 358 1.4E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS27390 23fe043fbb778f84672e48860f44f420 359 SUPERFAMILY SSF51679 7 357 1.06E-79 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 PIRSF PIRSF000124 6 417 4.1E-77 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 SMART SM00984 320 418 7.9E-25 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 190 3.4E-48 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 Gene3D G3DSA:3.40.50.720 242 417 4.8E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 SUPERFAMILY SSF52413 307 417 5.36E-25 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 SUPERFAMILY SSF48179 210 302 1.7E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 417 1.0E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 SUPERFAMILY SSF51735 8 203 9.98E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 PIRSF PIRSF500136 1 418 9.8E-141 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 414 1.4E-117 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 Gene3D G3DSA:3.40.50.720 4 231 1.8E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27480 f2203c62e1c92414ebee0c21cfaab55c 418 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 297 6.0E-28 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 SUPERFAMILY SSF54292 215 320 7.73E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 107 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 115 134 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 79 93 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 43 55 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 33 43 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 55 69 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 195 203 3.0E-42 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 272 280 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 SUPERFAMILY SSF52343 105 223 2.62E-27 T 06-07-2017 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Pfam PF00175 Oxidoreductase NAD-binding domain 116 209 8.3E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Gene3D G3DSA:3.10.20.30 222 315 1.9E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 312 7.3E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Gene3D G3DSA:2.40.30.10 10 103 1.1E-30 T 06-07-2017 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Gene3D G3DSA:3.40.50.80 106 221 2.1E-28 T 06-07-2017 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 Pfam PF00970 Oxidoreductase FAD-binding domain 11 103 1.5E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS05915 fa11275f44f3fcdc7088585405b52600 321 SUPERFAMILY SSF63380 9 102 3.05E-27 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 PRINTS PR00481 Cytosol aminopeptidase signature 221 238 2.9E-42 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 PRINTS PR00481 Cytosol aminopeptidase signature 280 301 2.9E-42 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 PRINTS PR00481 Cytosol aminopeptidase signature 243 264 2.9E-42 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 PRINTS PR00481 Cytosol aminopeptidase signature 330 345 2.9E-42 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 PRINTS PR00481 Cytosol aminopeptidase signature 302 322 2.9E-42 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 306 313 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 SUPERFAMILY SSF53187 141 455 5.34E-103 T 06-07-2017 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 147 434 1.3E-97 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK95_RS06690 991517f5295d78b5e004bcc964a0733e 457 Gene3D G3DSA:3.40.630.10 135 453 1.4E-110 T 06-07-2017 CAK95_RS23075 e5a61772d2de80986096219c8aaa547c 160 Gene3D G3DSA:3.30.70.640 4 158 1.1E-67 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK95_RS23075 e5a61772d2de80986096219c8aaa547c 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 5 153 1.7E-61 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CAK95_RS23075 e5a61772d2de80986096219c8aaa547c 160 Pfam PF01967 MoaC family 16 151 2.3E-56 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK95_RS23075 e5a61772d2de80986096219c8aaa547c 160 SUPERFAMILY SSF55040 12 156 5.23E-61 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK95_RS23075 e5a61772d2de80986096219c8aaa547c 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 3 159 36.551 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 CAK95_RS20925 c139376149e0f75461b08083c135ebfe 710 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 157 1.1E-20 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS20925 c139376149e0f75461b08083c135ebfe 710 Gene3D G3DSA:2.170.130.10 50 158 1.2E-29 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS20925 c139376149e0f75461b08083c135ebfe 710 Gene3D G3DSA:2.40.170.20 159 710 8.1E-70 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS20925 c139376149e0f75461b08083c135ebfe 710 SUPERFAMILY SSF56935 49 710 5.04E-92 T 06-07-2017 CAK95_RS20925 c139376149e0f75461b08083c135ebfe 710 Pfam PF00593 TonB dependent receptor 459 708 1.3E-20 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:1.10.3850.10 819 1032 1.5E-51 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:1.10.3850.10 282 502 6.4E-54 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Pfam PF00873 AcrB/AcrD/AcrF family 2 1030 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 39 132 3.61E-26 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 674 724 2.67E-22 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 811 860 2.67E-22 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 137 183 9.68E-26 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 278 334 9.68E-26 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:3.30.70.1430 569 673 4.1E-28 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 624 638 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 554 571 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 7.6E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1043 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82693 567 673 5.49E-26 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:3.30.70.1430 39 140 5.1E-32 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82714 184 276 1.06E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82866 300 501 5.62E-45 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82714 725 811 2.88E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 SUPERFAMILY SSF82866 834 1030 1.44E-43 T 06-07-2017 CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:3.30.2090.10 725 813 2.1E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS03980 9e8becf0bcfe0064e3121110aa216c41 1051 Gene3D G3DSA:3.30.2090.10 183 279 1.5E-24 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS06330 54596c1afb1f1d80049135bc555e9f2e 252 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS06330 54596c1afb1f1d80049135bc555e9f2e 252 SMART SM00382 32 214 2.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06330 54596c1afb1f1d80049135bc555e9f2e 252 SUPERFAMILY SSF52540 5 230 3.55E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06330 54596c1afb1f1d80049135bc555e9f2e 252 Pfam PF00005 ABC transporter 24 165 1.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS06330 54596c1afb1f1d80049135bc555e9f2e 252 Gene3D G3DSA:3.40.50.300 3 231 4.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04555 c4b0b422bc099b60a0070c6674715a70 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 33 161 1.2E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 448 465 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 SUPERFAMILY SSF53706 11 604 9.03E-160 T 06-07-2017 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Gene3D G3DSA:2.40.40.20 594 753 5.5E-53 T 06-07-2017 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Pfam PF00384 Molybdopterin oxidoreductase 52 503 4.2E-74 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Pfam PF01568 Molydopterin dinucleotide binding domain 620 735 6.5E-24 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Gene3D G3DSA:3.40.50.740 343 585 1.4E-70 T 06-07-2017 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Gene3D G3DSA:3.40.50.740 52 140 1.4E-70 T 06-07-2017 CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 SUPERFAMILY SSF50692 613 759 2.24E-38 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS05190 31aa4b676cf08c59c0950ca2392bb262 773 Gene3D G3DSA:3.40.228.10 141 342 4.3E-48 T 06-07-2017 CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 PIRSF PIRSF003128 1 556 2.2E-150 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 Gene3D G3DSA:3.40.50.300 1 206 4.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 Gene3D G3DSA:3.40.50.300 421 507 1.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 SUPERFAMILY SSF52540 298 507 1.93E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 SUPERFAMILY SSF52540 2 50 1.93E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 SUPERFAMILY SSF52540 1 215 1.71E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 506 1.4E-13 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 25 38 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK95_RS01740 3832866f3fa772975a5d38dc3a8db769 556 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 3.3E-137 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 76 96 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 25 50 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 142 168 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 55 70 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 97 117 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 1.1E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 SUPERFAMILY SSF50022 10 155 1.7E-44 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 SUPERFAMILY SSF55961 158 442 7.85E-52 T 06-07-2017 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 Pfam PF00355 Rieske [2Fe-2S] domain 41 123 1.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 Gene3D G3DSA:3.90.380.10 150 447 5.0E-63 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 Gene3D G3DSA:2.102.10.10 23 149 4.7E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27365 d03e71a86f3cb20781b1f05baa406467 452 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 437 2.8E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS22035 b455f67c52e7341ea52edf8110d22f94 288 Gene3D G3DSA:3.60.15.10 2 281 1.1E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22035 b455f67c52e7341ea52edf8110d22f94 288 SUPERFAMILY SSF56281 3 280 3.43E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22035 b455f67c52e7341ea52edf8110d22f94 288 SMART SM00849 57 261 8.3E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22035 b455f67c52e7341ea52edf8110d22f94 288 Pfam PF00753 Metallo-beta-lactamase superfamily 55 261 2.7E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 PIRSF PIRSF005499 1 719 4.8E-299 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 321 6.2E-21 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF55666 138 231 9.4E-29 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF00013 KH domain 557 614 2.2E-10 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF46915 238 322 4.97E-18 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Gene3D G3DSA:2.40.50.140 620 696 2.2E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SMART SM00316 621 691 1.2E-23 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Gene3D G3DSA:3.30.1370.10 552 619 5.7E-25 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SMART SM00322 553 618 1.9E-11 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF55666 451 549 4.64E-25 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Gene3D G3DSA:3.30.230.70 314 542 6.9E-86 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Gene3D G3DSA:3.30.230.70 8 225 1.1E-82 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 694 30.752 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF54211 295 489 8.1E-49 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF54211 4 144 6.07E-51 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 692 0.0 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 8.7E-22 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 1.2E-22 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF50249 621 704 5.38E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 SUPERFAMILY SSF54791 555 641 9.48E-23 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF03725 3' exoribonuclease family, domain 2 147 209 5.0E-11 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Gene3D G3DSA:1.10.10.400 238 313 1.3E-22 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK95_RS09145 b5a1939fd819c447d29b153e686593a8 719 Pfam PF00575 S1 RNA binding domain 620 691 2.6E-19 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 Pfam PF00625 Guanylate kinase 21 194 8.4E-7 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 17 193 29.593 T 06-07-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 18 193 5.0E-52 T 06-07-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 SMART SM00072 17 196 3.4E-5 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 Gene3D G3DSA:3.40.50.300 12 40 6.6E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 Gene3D G3DSA:3.40.50.300 89 165 6.6E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27890 5a11f421a18611d46d118d2f0ec91ce6 202 SUPERFAMILY SSF52540 14 198 1.32E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 Gene3D G3DSA:1.25.40.10 730 897 3.7E-52 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 Pfam PF08238 Sel1 repeat 848 883 4.8E-7 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 Pfam PF08238 Sel1 repeat 740 774 6.7E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 Pfam PF08238 Sel1 repeat 812 846 7.1E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 Pfam PF08238 Sel1 repeat 777 811 6.9E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 SUPERFAMILY SSF81901 730 887 2.35E-39 T 06-07-2017 CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 SMART SM00671 740 775 8.3E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 SMART SM00671 776 811 4.9E-7 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 SMART SM00671 848 883 6.7E-10 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS05620 4d50d18c580541bad5b6f6a3f4b6c76a 956 SMART SM00671 812 847 5.9E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 SMART SM00448 5 115 3.7E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 SUPERFAMILY SSF46894 131 233 6.52E-25 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 SUPERFAMILY SSF52172 5 132 1.32E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 232 3.4E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 Pfam PF00072 Response regulator receiver domain 7 116 1.7E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 Gene3D G3DSA:1.10.10.10 134 235 4.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 Gene3D G3DSA:3.40.50.2300 5 128 3.3E-41 T 06-07-2017 CAK95_RS11790 3442f1c44d2ac078b950b617f95d9667 239 SMART SM00862 156 232 4.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS08315 4f01fd9c0c4de7aaa266b4711c70c9ed 265 SUPERFAMILY SSF52540 13 241 1.67E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08315 4f01fd9c0c4de7aaa266b4711c70c9ed 265 Pfam PF00005 ABC transporter 30 171 5.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS08315 4f01fd9c0c4de7aaa266b4711c70c9ed 265 Gene3D G3DSA:3.40.50.300 12 231 4.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08315 4f01fd9c0c4de7aaa266b4711c70c9ed 265 SMART SM00382 39 221 2.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS08315 4f01fd9c0c4de7aaa266b4711c70c9ed 265 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 3.0E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 Gene3D G3DSA:1.10.357.10 24 219 3.0E-46 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 SUPERFAMILY SSF48498 97 217 5.82E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS00055 87671ed57b0f06ae8d0f49829cf1512a 251 SUPERFAMILY SSF46689 22 88 7.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Gene3D G3DSA:3.40.50.300 22 179 1.7E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 SUPERFAMILY SSF46785 259 332 1.48E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 PRINTS PR00819 CbxX/CfqX superfamily signature 169 188 6.7E-5 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 PRINTS PR00819 CbxX/CfqX superfamily signature 56 71 6.7E-5 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 330 5.0E-34 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Gene3D G3DSA:1.10.10.10 259 329 1.8E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 349 169.488 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Gene3D G3DSA:1.10.8.60 185 257 8.2E-31 T 06-07-2017 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 SMART SM00382 53 180 1.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 3.6E-32 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 SUPERFAMILY SSF52540 22 252 2.27E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 10 237 3.1E-114 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CAK95_RS04055 5a9d52e7801c647551681fb6543cbcf2 349 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 328 2.8E-138 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 4.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 Gene3D G3DSA:3.40.190.10 93 202 2.0E-18 T 06-07-2017 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 Gene3D G3DSA:1.10.10.10 12 92 2.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 Pfam PF03466 LysR substrate binding domain 100 302 8.8E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 Gene3D G3DSA:3.40.190.10 203 270 4.4E-10 T 06-07-2017 CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 SUPERFAMILY SSF46785 11 122 5.28E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12790 97eb0c6ea6dd2aac714874e1930cebb2 318 SUPERFAMILY SSF53850 100 306 3.88E-30 T 06-07-2017 CAK95_RS09200 0bf8844dc673159f29a4391c80d1bce3 135 Gene3D G3DSA:1.10.260.40 13 77 2.3E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS09200 0bf8844dc673159f29a4391c80d1bce3 135 SUPERFAMILY SSF47413 2 77 5.38E-29 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS09200 0bf8844dc673159f29a4391c80d1bce3 135 SMART SM00530 16 71 5.1E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS09200 0bf8844dc673159f29a4391c80d1bce3 135 Pfam PF01381 Helix-turn-helix 18 70 1.4E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS25495 d300117ecfa1f357e618fe4f12f67d79 163 Pfam PF00866 Ring hydroxylating beta subunit 22 155 7.5E-17 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAK95_RS25495 d300117ecfa1f357e618fe4f12f67d79 163 SUPERFAMILY SSF54427 7 159 3.22E-41 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25495 d300117ecfa1f357e618fe4f12f67d79 163 Gene3D G3DSA:3.10.450.50 10 153 1.4E-30 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS20275 e19bbe668dbeb4433b56ecc45699ff13 256 Gene3D G3DSA:3.40.50.150 43 245 1.8E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS20275 e19bbe668dbeb4433b56ecc45699ff13 256 Pfam PF08241 Methyltransferase domain 93 190 3.0E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS20275 e19bbe668dbeb4433b56ecc45699ff13 256 SUPERFAMILY SSF53335 72 246 4.03E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03825 1c07662ab5a652e23309b8115facd8fd 480 Pfam PF05170 AsmA family 144 329 6.3E-21 T 06-07-2017 IPR007844 AsmA CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 Gene3D G3DSA:3.40.50.970 222 364 2.2E-5 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 44 159 1.8E-16 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 Gene3D G3DSA:3.40.50.970 44 174 4.4E-20 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 SUPERFAMILY SSF52518 222 366 3.29E-12 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 SUPERFAMILY SSF52518 6 166 2.95E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04805 5ee7d5f02801fb5d0ea9a013b03d088d 385 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 56 75 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK95_RS07980 b943aacd781bc5c85b005738c3f8f4fb 212 Gene3D G3DSA:3.40.30.10 6 193 6.8E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS07980 b943aacd781bc5c85b005738c3f8f4fb 212 PIRSF PIRSF006386 1 208 3.0E-48 T 06-07-2017 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 CAK95_RS07980 b943aacd781bc5c85b005738c3f8f4fb 212 SUPERFAMILY SSF52833 6 205 4.47E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS07980 b943aacd781bc5c85b005738c3f8f4fb 212 Pfam PF01323 DSBA-like thioredoxin domain 7 193 1.6E-32 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAK95_RS01090 db636b7c35900c81136c0f367fc41b39 303 Gene3D G3DSA:3.30.1780.10 1 128 4.5E-16 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAK95_RS01090 db636b7c35900c81136c0f367fc41b39 303 PIRSF PIRSF001439 1 303 1.6E-44 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS01090 db636b7c35900c81136c0f367fc41b39 303 SUPERFAMILY SSF51735 1 300 2.08E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01090 db636b7c35900c81136c0f367fc41b39 303 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 76 300 4.5E-35 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS01090 db636b7c35900c81136c0f367fc41b39 303 Gene3D G3DSA:3.40.50.720 129 279 4.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20010 66db274b60e1fa8e7179546701e930b0 339 Gene3D G3DSA:3.90.850.10 305 317 3.7E-38 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20010 66db274b60e1fa8e7179546701e930b0 339 Gene3D G3DSA:3.90.850.10 65 268 3.7E-38 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20010 66db274b60e1fa8e7179546701e930b0 339 SUPERFAMILY SSF56529 75 334 1.57E-52 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20010 66db274b60e1fa8e7179546701e930b0 339 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 83 332 2.6E-38 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 36 263 5.0E-51 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 SMART SM00967 37 110 3.1E-13 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 Gene3D G3DSA:3.30.1330.30 34 106 1.1E-8 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 SUPERFAMILY SSF55315 35 107 1.18E-10 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 Gene3D G3DSA:3.40.1280.10 117 263 2.3E-45 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 Pfam PF00588 SpoU rRNA Methylase family 120 260 4.0E-36 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 37 108 7.6E-11 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK95_RS21015 f6d4ca54cbe0c69fd9974b94d1e253bb 268 SUPERFAMILY SSF75217 99 263 9.16E-43 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 Gene3D G3DSA:1.10.10.10 1 86 1.5E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 SUPERFAMILY SSF46785 1 111 7.57E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 Pfam PF03466 LysR substrate binding domain 88 291 2.8E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 Gene3D G3DSA:3.40.190.10 90 172 9.2E-18 T 06-07-2017 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 Gene3D G3DSA:3.40.190.10 173 264 5.2E-19 T 06-07-2017 CAK95_RS03365 3891d4189c95d2903c48d575a9333850 300 SUPERFAMILY SSF53850 90 293 6.81E-41 T 06-07-2017 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 SUPERFAMILY SSF50249 413 542 8.74E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Gene3D G3DSA:3.30.470.30 230 346 3.5E-23 T 06-07-2017 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Gene3D G3DSA:2.40.50.140 413 542 2.1E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 3 541 2.4E-247 T 06-07-2017 IPR026333 ATP-dependent DNA ligase, PP_1105 family CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Gene3D G3DSA:3.30.1490.70 358 409 1.7E-16 T 06-07-2017 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Gene3D G3DSA:3.30.1490.70 196 229 1.7E-16 T 06-07-2017 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Pfam PF01068 ATP dependent DNA ligase domain 204 408 1.4E-22 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 Pfam PF04679 ATP dependent DNA ligase C terminal region 429 526 1.7E-9 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAK95_RS05655 e9e3e7b20cd851afa9897cfaef1eec4e 556 SUPERFAMILY SSF56091 160 410 1.53E-47 T 06-07-2017 CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 4 282 41.307 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 Gene3D G3DSA:3.30.230.20 5 128 3.8E-41 T 06-07-2017 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 6 278 4.8E-98 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 291 1.3E-91 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 SUPERFAMILY SSF54211 5 127 4.63E-37 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 SUPERFAMILY SSF54211 137 281 5.69E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS01750 ca1a8caa7371f0ea20cbae1ae55a0b2d 314 Gene3D G3DSA:3.30.1700.10 132 284 1.7E-49 T 06-07-2017 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK95_RS09680 a2344e7a0813932f354b768256636baa 136 Pfam PF03960 ArsC family 6 113 4.1E-21 T 06-07-2017 IPR006660 Arsenate reductase-like CAK95_RS09680 a2344e7a0813932f354b768256636baa 136 Gene3D G3DSA:3.40.30.10 1 131 1.3E-57 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS09680 a2344e7a0813932f354b768256636baa 136 SUPERFAMILY SSF52833 2 131 2.03E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS09680 a2344e7a0813932f354b768256636baa 136 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 1.0E-40 T 06-07-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CAK95_RS19565 d502d18f687bdd696ca257c453eed161 124 Pfam PF07883 Cupin domain 38 106 1.4E-17 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS19565 d502d18f687bdd696ca257c453eed161 124 Gene3D G3DSA:2.60.120.10 19 110 3.6E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS19565 d502d18f687bdd696ca257c453eed161 124 SUPERFAMILY SSF51182 23 108 6.62E-23 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Gene3D G3DSA:1.10.166.10 4 72 3.6E-27 T 06-07-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 170 1.1E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 3 281 55.74 T 06-07-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 179 214 1.6E-12 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Gene3D G3DSA:2.160.10.10 93 263 9.5E-55 T 06-07-2017 CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 71 1.2E-22 T 06-07-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 SUPERFAMILY SSF51161 17 265 1.8E-66 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS02800 c21178e5728ed96e2d9736c1755e6f93 281 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 280 1.3E-125 T 06-07-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CAK95_RS18485 e5a8c967893d81745b0b160c021280c2 257 Pfam PF09836 Putative DNA-binding domain 4 95 5.6E-25 T 06-07-2017 IPR018640 Putative DNA-binding domain, bacteria CAK95_RS05800 a816a5de75da62a00bfb921bfd4ee703 93 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 1.0E-19 T 06-07-2017 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CAK95_RS05800 a816a5de75da62a00bfb921bfd4ee703 93 PIRSF PIRSF001486 1 93 7.9E-46 T 06-07-2017 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CAK95_RS05800 a816a5de75da62a00bfb921bfd4ee703 93 Pfam PF02426 Muconolactone delta-isomerase 1 89 3.3E-41 T 06-07-2017 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CAK95_RS05800 a816a5de75da62a00bfb921bfd4ee703 93 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 1.3E-45 T 06-07-2017 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CAK95_RS05800 a816a5de75da62a00bfb921bfd4ee703 93 SUPERFAMILY SSF54909 1 91 6.43E-39 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS10750 b33d6420c93f15f7a5da73b0a7b563f4 217 Pfam PF08241 Methyltransferase domain 70 126 3.3E-6 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS10750 b33d6420c93f15f7a5da73b0a7b563f4 217 SUPERFAMILY SSF53335 10 208 1.03E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10750 b33d6420c93f15f7a5da73b0a7b563f4 217 Gene3D G3DSA:3.40.50.150 20 196 2.2E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 PIRSF PIRSF001365 2 305 6.9E-59 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 SMART SM01130 6 297 9.3E-71 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 4.2E-9 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 4.2E-9 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 4.2E-9 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 Gene3D G3DSA:3.20.20.70 2 298 3.3E-74 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 SUPERFAMILY SSF51569 3 298 5.02E-69 T 06-07-2017 CAK95_RS05195 94240aef770321fc47f20ac0555a1fe6 314 Pfam PF00701 Dihydrodipicolinate synthetase family 8 290 4.5E-50 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS00300 756e411ef35f18ba0590bb5aa90a77c9 425 PIRSF PIRSF006066 1 424 2.3E-128 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS00300 756e411ef35f18ba0590bb5aa90a77c9 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 415 8.8E-105 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS00300 756e411ef35f18ba0590bb5aa90a77c9 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 418 1.7E-123 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 Hamap MF_00268 Protein RecA [recA]. 16 341 51.92 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 139 168 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 177 206 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 309 326 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 222 250 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 255 284 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 PRINTS PR00142 RecA protein signature 105 134 4.3E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 SMART SM00382 69 240 7.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 Gene3D G3DSA:3.30.250.10 280 337 5.9E-26 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 Gene3D G3DSA:3.40.50.300 43 279 3.7E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 SUPERFAMILY SSF52540 17 279 3.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 15 336 5.9E-175 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 Pfam PF00154 recA bacterial DNA recombination protein 18 280 2.7E-148 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 SUPERFAMILY SSF54752 280 337 5.23E-21 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAK95_RS26600 d89f4560e57f6f37bc45706b9b4a44cd 361 ProSitePatterns PS00321 recA signature. 225 233 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 Gene3D G3DSA:3.90.550.10 451 694 2.1E-31 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 Pfam PF13641 Glycosyltransferase like family 2 451 680 1.3E-30 T 06-07-2017 CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 SUPERFAMILY SSF53448 446 697 1.9E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 Gene3D G3DSA:3.20.20.80 53 138 2.9E-24 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 Gene3D G3DSA:3.20.20.80 173 327 2.9E-24 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 SUPERFAMILY SSF51445 173 328 1.21E-44 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS23680 82bafc40b3515df60dfb9170a2d1944c 931 SUPERFAMILY SSF51445 38 139 1.21E-44 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 3 255 41.08 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 172 255 1.6E-25 T 06-07-2017 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 Pfam PF00753 Metallo-beta-lactamase superfamily 21 171 6.5E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 PIRSF PIRSF005457 1 255 7.2E-99 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 255 1.4E-93 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 SUPERFAMILY SSF56281 5 255 4.6E-67 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 SMART SM00849 13 171 1.5E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10365 34e8199b0a7ba9d958937e6bc09ea615 255 Gene3D G3DSA:3.60.15.10 6 255 3.1E-80 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS11460 42dc2a9b916435a5876615e5c2fbda56 261 Gene3D G3DSA:1.10.12.10 205 260 1.7E-14 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS11460 42dc2a9b916435a5876615e5c2fbda56 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 260 1.9E-45 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS11460 42dc2a9b916435a5876615e5c2fbda56 261 SUPERFAMILY SSF52096 15 260 1.57E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11460 42dc2a9b916435a5876615e5c2fbda56 261 Gene3D G3DSA:3.90.226.10 15 203 2.4E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25855 47b773e300d5190c9aa62ba566c7b631 344 Gene3D G3DSA:3.40.718.10 4 337 2.7E-122 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS25855 47b773e300d5190c9aa62ba566c7b631 344 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 330 2.3E-99 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK95_RS25855 47b773e300d5190c9aa62ba566c7b631 344 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 334 33.287 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK95_RS25855 47b773e300d5190c9aa62ba566c7b631 344 SUPERFAMILY SSF53659 7 335 2.02E-104 T 06-07-2017 CAK95_RS25855 47b773e300d5190c9aa62ba566c7b631 344 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 334 2.1E-121 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 SUPERFAMILY SSF54427 192 294 2.67E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 Gene3D G3DSA:1.10.10.10 127 177 5.5E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 Pfam PF08281 Sigma-70, region 4 129 174 3.7E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 SUPERFAMILY SSF88659 114 177 3.71E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 Gene3D G3DSA:3.10.450.50 188 290 6.5E-13 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 Pfam PF04542 Sigma-70 region 2 21 90 4.0E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 SUPERFAMILY SSF88946 20 110 1.73E-17 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 2.3E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05440 b50b0f1897689893da41a7b386d8d6ec 314 Gene3D G3DSA:1.10.1740.10 20 112 6.0E-20 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 Gene3D G3DSA:3.50.50.60 137 329 2.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 Gene3D G3DSA:3.30.390.30 339 454 3.5E-45 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 9.6E-34 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 SUPERFAMILY SSF55424 336 454 1.41E-36 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 SUPERFAMILY SSF51905 6 373 1.51E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.8E-68 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 449 3.1E-199 T 06-07-2017 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PIRSF PIRSF000350 2 456 3.7E-89 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 Gene3D G3DSA:3.50.50.60 5 136 3.0E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 320 1.0E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 4.2E-27 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 4.2E-27 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.2E-27 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 4.2E-27 T 06-07-2017 CAK95_RS19940 5dc30d99790c413c4813075c1214ad53 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 4.2E-27 T 06-07-2017 CAK95_RS14535 57545e8d99eb4d0ea45f61da62b224dd 243 Gene3D G3DSA:3.40.50.1820 2 236 1.7E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14535 57545e8d99eb4d0ea45f61da62b224dd 243 SUPERFAMILY SSF53474 2 237 1.02E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14535 57545e8d99eb4d0ea45f61da62b224dd 243 Pfam PF01738 Dienelactone hydrolase family 24 237 8.6E-33 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK95_RS13530 43c17f0c80401c7ae6bb22b3b73e63e7 166 Pfam PF10722 Putative bacterial sensory transduction regulator 14 143 8.5E-31 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN CAK95_RS00270 d11a79bb0df68953fb4874ee583f0db8 440 Pfam PF00005 ABC transporter 17 163 4.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS00270 d11a79bb0df68953fb4874ee583f0db8 440 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00270 d11a79bb0df68953fb4874ee583f0db8 440 SMART SM00382 26 253 7.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00270 d11a79bb0df68953fb4874ee583f0db8 440 SUPERFAMILY SSF52540 2 234 6.35E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00270 d11a79bb0df68953fb4874ee583f0db8 440 Gene3D G3DSA:3.40.50.300 1 229 4.1E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Pfam PF12860 PAS fold 649 761 7.9E-33 T 06-07-2017 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Gene3D G3DSA:3.30.450.20 634 755 9.3E-9 T 06-07-2017 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SMART SM00388 795 860 1.5E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Gene3D G3DSA:3.40.50.2300 1031 1151 5.6E-17 T 06-07-2017 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SUPERFAMILY SSF52172 1034 1151 6.83E-18 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SUPERFAMILY SSF47384 780 860 3.14E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SMART SM00387 904 1014 5.3E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SMART SM00448 1035 1148 2.1E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Gene3D G3DSA:3.30.565.10 862 1015 3.7E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 905 1012 5.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Gene3D G3DSA:1.10.287.130 789 856 5.8E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SUPERFAMILY SSF55874 851 1012 1.44E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 940 954 1.4E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 998 1011 1.4E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 974 992 1.4E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 SUPERFAMILY SSF55785 634 755 2.2E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Pfam PF00512 His Kinase A (phospho-acceptor) domain 795 860 4.0E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05570 e8ffefc7299e71b1e12a840ccd06819f 1159 Pfam PF00072 Response regulator receiver domain 1037 1148 5.1E-11 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 Gene3D G3DSA:3.40.50.10490 64 209 2.8E-27 T 06-07-2017 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 412 429 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 SUPERFAMILY SSF53697 37 437 1.48E-84 T 06-07-2017 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 Gene3D G3DSA:3.40.50.10490 210 421 6.4E-62 T 06-07-2017 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 Pfam PF00342 Phosphoglucose isomerase 74 299 2.3E-14 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 380 398 3.1E-11 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 277 298 3.1E-11 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 3.1E-11 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 412 425 3.1E-11 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS13330 1d0decc8162491cd236c5541f37be801 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 200 218 3.1E-11 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 136 148 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 157 177 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 254 271 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 340 352 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 6.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SUPERFAMILY SSF50156 419 508 9.6E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SUPERFAMILY SSF50156 285 390 1.89E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SUPERFAMILY SSF50494 124 309 3.0E-66 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SUPERFAMILY SSF50494 18 58 3.0E-66 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Gene3D G3DSA:2.40.10.10 193 301 6.5E-47 T 06-07-2017 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Gene3D G3DSA:2.40.10.10 28 58 3.0E-34 T 06-07-2017 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Gene3D G3DSA:2.40.10.10 114 192 3.0E-34 T 06-07-2017 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Pfam PF13180 PDZ domain 300 391 7.2E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SMART SM00228 300 382 5.9E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 SMART SM00228 419 503 7.9E-6 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Pfam PF13365 Trypsin-like peptidase domain 127 261 2.6E-36 T 06-07-2017 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 39 502 3.5E-147 T 06-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Gene3D G3DSA:2.30.42.10 302 396 5.1E-27 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14630 c7e530d19307db4743b4cad3b3ada90c 515 Gene3D G3DSA:2.30.42.10 420 512 1.2E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14265 c61964d071ae23b56a9fa3abaa25b3d7 177 Gene3D G3DSA:2.60.120.10 26 170 1.8E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS14265 c61964d071ae23b56a9fa3abaa25b3d7 177 SUPERFAMILY SSF51182 56 170 2.19E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS14265 c61964d071ae23b56a9fa3abaa25b3d7 177 Pfam PF07883 Cupin domain 77 146 2.5E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 Gene3D G3DSA:3.40.50.2300 32 234 4.4E-52 T 06-07-2017 CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 75 93 7.5E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 304 317 7.5E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 56 72 7.5E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 34 50 7.5E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 SUPERFAMILY SSF53822 34 385 1.34E-75 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS27650 579a41e2fe41c9445e426184527da3b4 394 Pfam PF13458 Periplasmic binding protein 33 363 1.8E-57 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 SUPERFAMILY SSF54292 2 99 1.21E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 Gene3D G3DSA:3.10.20.30 2 99 1.5E-31 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 38 48 - T 06-07-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 88 6.4E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 PRINTS PR00355 Adrenodoxin signature 38 48 3.8E-7 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 PRINTS PR00355 Adrenodoxin signature 80 88 3.8E-7 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS03720 7cc8ad431b5b566b8171b004b2262387 105 PRINTS PR00355 Adrenodoxin signature 57 71 3.8E-7 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Pfam PF08447 PAS fold 269 354 2.1E-13 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SUPERFAMILY SSF55785 257 363 2.09E-15 T 06-07-2017 IPR000014 PAS domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 751 7.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 732 7.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 693 7.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Pfam PF12860 PAS fold 380 484 6.6E-10 T 06-07-2017 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Gene3D G3DSA:3.30.450.20 362 424 1.1E-6 T 06-07-2017 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 269 368 1.1E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SMART SM00086 320 362 1.4E-5 T 06-07-2017 IPR001610 PAC motif CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SUPERFAMILY SSF55874 586 750 1.83E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Gene3D G3DSA:3.30.450.20 246 361 8.2E-20 T 06-07-2017 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Gene3D G3DSA:1.10.287.130 533 583 6.3E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Gene3D G3DSA:3.30.565.10 584 752 6.6E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SUPERFAMILY SSF47384 513 598 6.28E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Pfam PF00512 His Kinase A (phospho-acceptor) domain 528 597 5.4E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SMART SM00091 374 440 2.5 T 06-07-2017 IPR000014 PAS domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SMART SM00091 246 316 3.9 T 06-07-2017 IPR000014 PAS domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SMART SM00387 642 754 4.3E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Gene3D G3DSA:3.30.450.20 464 532 2.4E-5 T 06-07-2017 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SMART SM00388 528 597 1.4E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 SUPERFAMILY SSF55785 358 414 8.76E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS19200 66fb9bb531dde6d622bc36e3b05aacd7 762 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 643 752 1.5E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Pfam PF00563 EAL domain 543 772 2.0E-70 T 06-07-2017 IPR001633 EAL domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 SUPERFAMILY SSF55073 370 527 3.69E-45 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 SMART SM00267 354 526 3.2E-61 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Gene3D G3DSA:3.30.70.270 366 533 2.9E-52 T 06-07-2017 CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Gene3D G3DSA:3.20.20.450 540 785 4.5E-92 T 06-07-2017 IPR001633 EAL domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 521 1.0E-45 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 SMART SM00052 536 778 2.6E-108 T 06-07-2017 IPR001633 EAL domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Pfam PF03707 Bacterial signalling protein N terminal repeat 58 109 1.5E-14 T 06-07-2017 IPR005330 MHYT domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 164 6.6E-10 T 06-07-2017 IPR005330 MHYT domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Pfam PF13188 PAS domain 251 296 1.8E-4 T 06-07-2017 IPR000014 PAS domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 524 4.6E-39 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 SUPERFAMILY SSF55785 269 362 3.81E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 258 360 4.1E-8 T 06-07-2017 IPR000014 PAS domain CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 Gene3D G3DSA:3.30.450.20 250 350 1.9E-8 T 06-07-2017 CAK95_RS26470 3e97c33f2e768d18d0ef6fd8a2208995 808 SUPERFAMILY SSF141868 541 785 1.31E-87 T 06-07-2017 IPR001633 EAL domain CAK95_RS21435 b24a79a3b1e5c5c7091343b3ae730fcb 394 SUPERFAMILY SSF55073 220 372 1.73E-44 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS21435 b24a79a3b1e5c5c7091343b3ae730fcb 394 Gene3D G3DSA:3.30.70.270 217 375 1.6E-49 T 06-07-2017 CAK95_RS21435 b24a79a3b1e5c5c7091343b3ae730fcb 394 Pfam PF00990 Diguanylate cyclase, GGDEF domain 217 369 3.9E-42 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS21435 b24a79a3b1e5c5c7091343b3ae730fcb 394 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 216 372 1.8E-42 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS21435 b24a79a3b1e5c5c7091343b3ae730fcb 394 SMART SM00267 204 373 4.4E-49 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS28045 146f2a53ab0f7fe19dbcd8db9a880569 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 11 314 6.3E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28045 146f2a53ab0f7fe19dbcd8db9a880569 339 SUPERFAMILY SSF51735 7 321 1.5E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28045 146f2a53ab0f7fe19dbcd8db9a880569 339 Gene3D G3DSA:3.90.25.10 197 322 5.7E-30 T 06-07-2017 CAK95_RS28045 146f2a53ab0f7fe19dbcd8db9a880569 339 Gene3D G3DSA:3.40.50.720 9 196 1.5E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14595 3bded40f66a0cb54a22b10bfe6e9f5ab 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 1.8E-147 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS26805 92d9aa41fff3bbbdae8d202d4cd64b45 453 SUPERFAMILY SSF53383 76 439 4.89E-103 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS26805 92d9aa41fff3bbbdae8d202d4cd64b45 453 Gene3D G3DSA:3.40.640.10 107 324 2.1E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS26805 92d9aa41fff3bbbdae8d202d4cd64b45 453 Gene3D G3DSA:3.90.1150.10 325 431 1.3E-22 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS26805 92d9aa41fff3bbbdae8d202d4cd64b45 453 Pfam PF00155 Aminotransferase class I and II 90 431 4.7E-54 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS27285 8df7d1cea24621ec1bd8e7a8f5b103f6 327 Pfam PF00701 Dihydrodipicolinate synthetase family 16 311 4.3E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS27285 8df7d1cea24621ec1bd8e7a8f5b103f6 327 Gene3D G3DSA:3.20.20.70 11 317 1.4E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS27285 8df7d1cea24621ec1bd8e7a8f5b103f6 327 SUPERFAMILY SSF51569 16 314 9.84E-57 T 06-07-2017 CAK95_RS27285 8df7d1cea24621ec1bd8e7a8f5b103f6 327 SMART SM01130 15 315 7.0E-41 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS27285 8df7d1cea24621ec1bd8e7a8f5b103f6 327 PIRSF PIRSF001365 12 326 1.8E-42 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS20885 355fb8a9e7021ec3b01a0eafac10d5bf 197 SUPERFAMILY SSF47226 53 151 8.64E-12 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS20885 355fb8a9e7021ec3b01a0eafac10d5bf 197 Gene3D G3DSA:1.20.120.160 53 127 6.3E-7 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS20885 355fb8a9e7021ec3b01a0eafac10d5bf 197 Pfam PF01627 Hpt domain 70 144 3.4E-6 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS05825 73d9f436ee2bef14928b2f008dc758eb 390 Pfam PF10129 OpgC protein 23 378 1.1E-130 T 06-07-2017 IPR014550 Uncharacterised conserved protein UCP028704, OpgC CAK95_RS05825 73d9f436ee2bef14928b2f008dc758eb 390 PIRSF PIRSF028704 6 389 1.3E-147 T 06-07-2017 IPR014550 Uncharacterised conserved protein UCP028704, OpgC CAK95_RS28340 3e4e43ee86450f71044f091d43a18b40 465 SUPERFAMILY SSF53850 108 332 8.24E-36 T 06-07-2017 CAK95_RS28340 3e4e43ee86450f71044f091d43a18b40 465 Gene3D G3DSA:3.40.190.10 214 335 3.4E-11 T 06-07-2017 CAK95_RS28340 3e4e43ee86450f71044f091d43a18b40 465 Pfam PF13379 NMT1-like family 107 344 2.7E-79 T 06-07-2017 CAK95_RS11050 576b158506063064aa42660ee73b618c 523 Gene3D G3DSA:3.90.1200.10 109 127 4.9E-11 T 06-07-2017 CAK95_RS11050 576b158506063064aa42660ee73b618c 523 Gene3D G3DSA:3.90.1200.10 251 313 4.9E-11 T 06-07-2017 CAK95_RS11050 576b158506063064aa42660ee73b618c 523 SUPERFAMILY SSF56112 195 435 1.48E-43 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS11050 576b158506063064aa42660ee73b618c 523 SUPERFAMILY SSF56112 95 160 1.48E-43 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS11050 576b158506063064aa42660ee73b618c 523 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 10 440 8.1E-163 T 06-07-2017 IPR010232 Probable protein kinase UbiB GO:0006744 CAK95_RS11050 576b158506063064aa42660ee73b618c 523 Pfam PF03109 ABC1 family 114 232 6.2E-29 T 06-07-2017 IPR004147 UbiB domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Pfam PF00072 Response regulator receiver domain 588 699 8.9E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00448 586 699 2.9E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Pfam PF08448 PAS fold 216 322 9.7E-13 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00086 159 197 100.0 T 06-07-2017 IPR001610 PAC motif CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00086 280 322 0.022 T 06-07-2017 IPR001610 PAC motif CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SUPERFAMILY SSF52172 585 704 2.56E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Pfam PF08447 PAS fold 111 179 1.2E-10 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Gene3D G3DSA:3.40.50.2300 585 704 1.1E-32 T 06-07-2017 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Pfam PF00512 His Kinase A (phospho-acceptor) domain 339 401 2.4E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00091 87 153 1.2E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00091 209 274 4.1E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 565 3.3E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Gene3D G3DSA:3.30.450.20 210 320 7.8E-24 T 06-07-2017 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Gene3D G3DSA:3.30.565.10 390 566 7.7E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00387 444 567 6.1E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SMART SM00388 337 403 2.3E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Gene3D G3DSA:3.30.450.20 87 209 1.7E-24 T 06-07-2017 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 Gene3D G3DSA:1.10.287.130 331 389 1.9E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SUPERFAMILY SSF55785 193 312 6.94E-23 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SUPERFAMILY SSF55785 92 199 4.06E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 564 3.9E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 524 3.9E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 3.9E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 510 3.9E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS20650 884ad455d550409c16e891482457f1be 705 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 205 329 1.6E-20 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 90 203 7.0E-17 T 06-07-2017 IPR000014 PAS domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SUPERFAMILY SSF55874 394 567 4.45E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20650 884ad455d550409c16e891482457f1be 705 SUPERFAMILY SSF47384 327 400 1.8E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08930 a490828b1d7e31414bb6f24974299f83 193 Gene3D G3DSA:3.40.50.360 2 190 2.1E-48 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS08930 a490828b1d7e31414bb6f24974299f83 193 Pfam PF03358 NADPH-dependent FMN reductase 4 159 2.2E-32 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS08930 a490828b1d7e31414bb6f24974299f83 193 SUPERFAMILY SSF52218 4 189 1.76E-37 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS10865 cb1c9258df9df866ef4aff20c66eb77b 324 SUPERFAMILY SSF81345 2 317 5.89E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS10865 cb1c9258df9df866ef4aff20c66eb77b 324 Pfam PF01032 FecCD transport family 2 317 1.9E-88 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAK95_RS10865 cb1c9258df9df866ef4aff20c66eb77b 324 Gene3D G3DSA:1.10.3470.10 2 319 2.8E-98 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Gene3D G3DSA:2.60.40.420 80 195 2.8E-28 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Pfam PF07732 Multicopper oxidase 94 197 2.3E-32 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Gene3D G3DSA:2.60.40.420 196 312 6.7E-17 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Gene3D G3DSA:2.60.40.420 414 493 3.8E-13 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Pfam PF00394 Multicopper oxidase 231 313 1.4E-7 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 SUPERFAMILY SSF49503 98 220 1.24E-33 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 SUPERFAMILY SSF49503 199 315 2.24E-16 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 SUPERFAMILY SSF49503 396 487 8.57E-16 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS22690 52e5eb4f753501298fe00f79bb3f4068 507 Pfam PF07731 Multicopper oxidase 405 488 1.2E-10 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 Pfam PF07702 UTRA domain 99 237 1.8E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 Gene3D G3DSA:3.40.1410.10 73 244 2.0E-38 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 SUPERFAMILY SSF64288 64 244 1.73E-39 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 SMART SM00345 17 76 4.1E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 SMART SM00866 96 238 1.0E-24 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 Gene3D G3DSA:1.10.10.10 8 72 3.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26565 7892792dfdf6461db9dd689765688428 244 SUPERFAMILY SSF46785 6 80 3.85E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 SUPERFAMILY SSF51905 369 408 1.44E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 SUPERFAMILY SSF51905 3 290 1.44E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 5 408 1.9E-117 T 06-07-2017 IPR017830 Squalene-associated FAD-dependent desaturase CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 Gene3D G3DSA:3.50.50.60 204 283 6.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 Gene3D G3DSA:3.50.50.60 3 41 6.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 Gene3D G3DSA:3.50.50.60 369 408 6.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 Pfam PF01593 Flavin containing amine oxidoreductase 12 281 4.2E-23 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS04490 7cea76a9a2d38e3cf0c4169f770d8313 411 Pfam PF01593 Flavin containing amine oxidoreductase 316 406 2.5E-12 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Pfam PF00501 AMP-binding enzyme 107 509 1.1E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Pfam PF13193 AMP-binding enzyme C-terminal domain 518 596 4.2E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Gene3D G3DSA:3.40.50.980 105 262 1.2E-36 T 06-07-2017 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Gene3D G3DSA:3.30.300.30 505 605 1.5E-26 T 06-07-2017 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Gene3D G3DSA:3.40.50.980 263 427 8.0E-33 T 06-07-2017 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 Gene3D G3DSA:2.30.38.10 429 503 2.2E-18 T 06-07-2017 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 95 604 1.0E-151 T 06-07-2017 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CAK95_RS03280 e48a67e6cdc4656ccb49af7885826927 612 SUPERFAMILY SSF56801 88 604 6.54E-142 T 06-07-2017 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 Gene3D G3DSA:3.40.190.10 94 186 1.6E-21 T 06-07-2017 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 Gene3D G3DSA:1.10.10.10 3 85 2.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 SUPERFAMILY SSF53850 90 295 1.35E-45 T 06-07-2017 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 Gene3D G3DSA:3.40.190.10 187 253 1.7E-4 T 06-07-2017 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 7.5E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 Pfam PF03466 LysR substrate binding domain 89 291 8.6E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS08750 42c8abe52ffc149c497d6032a0ccf6fa 297 SUPERFAMILY SSF46785 3 112 1.68E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23785 af2049ec6923b5cd061f7c2db2508772 153 Pfam PF07883 Cupin domain 46 117 8.3E-21 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS23785 af2049ec6923b5cd061f7c2db2508772 153 SUPERFAMILY SSF51182 23 120 2.25E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS23785 af2049ec6923b5cd061f7c2db2508772 153 Gene3D G3DSA:2.60.120.10 2 118 5.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 4.8E-46 T 06-07-2017 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 Gene3D G3DSA:1.10.1660.10 1 55 1.5E-25 T 06-07-2017 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 SUPERFAMILY SSF46955 1 126 2.12E-35 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 Gene3D G3DSA:1.10.1660.10 56 130 1.2E-25 T 06-07-2017 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 SMART SM00422 1 70 3.8E-29 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 Pfam PF00376 MerR family regulatory protein 2 39 2.2E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19640 74e59c906c5d5b2ca90c554aaa98cbc3 150 Pfam PF09278 MerR, DNA binding 44 108 2.0E-17 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 Gene3D G3DSA:3.40.190.10 177 261 4.4E-25 T 06-07-2017 CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 SUPERFAMILY SSF53850 89 297 3.98E-41 T 06-07-2017 CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 Gene3D G3DSA:1.10.10.10 3 84 2.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.9E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 Gene3D G3DSA:3.40.190.10 92 176 2.1E-5 T 06-07-2017 CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 Pfam PF03466 LysR substrate binding domain 89 294 4.5E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS23820 47c4d54d9b875f111cc28278661d5e71 299 SUPERFAMILY SSF46785 4 84 3.27E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10305 929c1106990556671fe78a423ceb1872 310 Gene3D G3DSA:1.10.600.10 8 308 4.0E-87 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS10305 929c1106990556671fe78a423ceb1872 310 Pfam PF00348 Polyprenyl synthetase 43 273 9.3E-51 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK95_RS10305 929c1106990556671fe78a423ceb1872 310 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 108 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK95_RS10305 929c1106990556671fe78a423ceb1872 310 SUPERFAMILY SSF48576 17 300 7.52E-79 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS10305 929c1106990556671fe78a423ceb1872 310 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 229 241 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK95_RS26485 ee9b1794146e4c10c154b0dd7c6b5db8 78 Gene3D G3DSA:3.30.300.90 1 77 1.8E-21 T 06-07-2017 IPR002634 BolA protein CAK95_RS26485 ee9b1794146e4c10c154b0dd7c6b5db8 78 PIRSF PIRSF003113 1 78 3.4E-18 T 06-07-2017 IPR002634 BolA protein CAK95_RS26485 ee9b1794146e4c10c154b0dd7c6b5db8 78 SUPERFAMILY SSF82657 1 77 1.28E-22 T 06-07-2017 IPR002634 BolA protein CAK95_RS26485 ee9b1794146e4c10c154b0dd7c6b5db8 78 Pfam PF01722 BolA-like protein 27 76 4.2E-14 T 06-07-2017 IPR002634 BolA protein CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 Gene3D G3DSA:3.40.50.20 22 101 8.8E-5 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 SUPERFAMILY SSF56059 114 326 1.1E-29 T 06-07-2017 CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 Gene3D G3DSA:3.30.470.20 197 336 7.0E-30 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 Pfam PF07478 D-ala D-ala ligase C-terminus 141 327 1.7E-24 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 SUPERFAMILY SSF52440 22 110 1.73E-8 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS24905 6319281cb10cec8c4e003fa1273f9d2c 338 Gene3D G3DSA:3.30.1490.20 111 196 6.3E-6 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 Gene3D G3DSA:2.60.120.280 14 105 2.0E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 SUPERFAMILY SSF46689 211 259 4.08E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 240 2.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 256 2.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 SMART SM00342 174 256 1.2E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 Pfam PF12833 Helix-turn-helix domain 180 257 2.1E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 252 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 SUPERFAMILY SSF51182 17 183 1.69E-10 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 Gene3D G3DSA:1.10.10.60 153 211 5.8E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 Gene3D G3DSA:1.10.10.60 212 258 1.7E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15840 caa18ed8b7648bde7b194eb36e0cc6ce 268 Pfam PF02311 AraC-like ligand binding domain 26 103 1.3E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS08180 6698a455a7422aeeb21c3f3cd55e39dc 223 SUPERFAMILY SSF51419 4 220 2.76E-68 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS08180 6698a455a7422aeeb21c3f3cd55e39dc 223 PIRSF PIRSF004848 1 223 2.6E-60 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAK95_RS08180 6698a455a7422aeeb21c3f3cd55e39dc 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 8 222 2.5E-49 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAK95_RS08180 6698a455a7422aeeb21c3f3cd55e39dc 223 Gene3D G3DSA:3.20.20.10 3 222 1.1E-74 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS08180 6698a455a7422aeeb21c3f3cd55e39dc 223 Pfam PF01168 Alanine racemase, N-terminal domain 13 222 1.8E-18 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS21145 9f3acb0a51fdcf0fd65208d29e871e2c 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 212 2.6E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21145 9f3acb0a51fdcf0fd65208d29e871e2c 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 3.4E-29 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS21145 9f3acb0a51fdcf0fd65208d29e871e2c 220 Gene3D G3DSA:1.10.3720.10 12 214 1.8E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21145 9f3acb0a51fdcf0fd65208d29e871e2c 220 SUPERFAMILY SSF161098 14 202 8.9E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Gene3D G3DSA:2.40.170.20 296 841 2.2E-69 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Pfam PF13505 Outer membrane protein beta-barrel domain 862 1121 1.1E-17 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 249 4.0E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Pfam PF07660 Secretin and TonB N terminus short domain 60 109 1.6E-9 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Gene3D G3DSA:2.40.160.20 863 1058 1.9E-33 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Gene3D G3DSA:2.40.160.20 1103 1121 1.9E-33 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 SUPERFAMILY SSF56925 863 1060 4.71E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 SUPERFAMILY SSF56925 1105 1121 4.71E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Gene3D G3DSA:2.170.130.10 143 264 4.3E-30 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 Pfam PF00593 TonB dependent receptor 576 838 4.6E-27 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 SUPERFAMILY SSF56935 363 841 8.55E-78 T 06-07-2017 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 SUPERFAMILY SSF56935 120 334 8.55E-78 T 06-07-2017 CAK95_RS07875 b86e8e8f31bc3a95a9fae07fe3e121cc 1121 SMART SM00965 59 110 4.2E-14 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 SUPERFAMILY SSF51735 112 291 4.81E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 Gene3D G3DSA:3.40.50.720 12 124 5.5E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 Gene3D G3DSA:3.40.50.720 125 291 5.8E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 49 322 7.6E-22 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 291 2.9E-48 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS10180 b426487e8311cc55b951353494530ea4 324 SUPERFAMILY SSF52283 11 145 5.48E-29 T 06-07-2017 CAK95_RS13505 c56b8fe0f4478ed7805139dea55c18f3 276 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 269 3.3E-71 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK95_RS13505 c56b8fe0f4478ed7805139dea55c18f3 276 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 147 159 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK95_RS13505 c56b8fe0f4478ed7805139dea55c18f3 276 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 264 9.0E-77 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK95_RS13505 c56b8fe0f4478ed7805139dea55c18f3 276 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 269 19.036 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK95_RS04980 f6dde4176164169b7eca8a83574dd51d 530 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 5 420 4.7E-90 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS04980 f6dde4176164169b7eca8a83574dd51d 530 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 9 392 3.9E-101 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS04980 f6dde4176164169b7eca8a83574dd51d 530 SUPERFAMILY SSF143968 291 436 4.58E-34 T 06-07-2017 CAK95_RS04980 f6dde4176164169b7eca8a83574dd51d 530 SUPERFAMILY SSF50475 3 287 1.28E-72 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS04980 f6dde4176164169b7eca8a83574dd51d 530 Gene3D G3DSA:3.40.1670.10 306 420 2.7E-30 T 06-07-2017 CAK95_RS23730 9d5810f377fcedcc27528c5759a1ba31 505 SUPERFAMILY SSF56935 75 228 4.76E-6 T 06-07-2017 CAK95_RS23730 9d5810f377fcedcc27528c5759a1ba31 505 SUPERFAMILY SSF56935 371 402 4.76E-6 T 06-07-2017 CAK95_RS23730 9d5810f377fcedcc27528c5759a1ba31 505 SUPERFAMILY SSF56935 435 484 4.76E-6 T 06-07-2017 CAK95_RS23730 9d5810f377fcedcc27528c5759a1ba31 505 SUPERFAMILY SSF56935 300 341 4.76E-6 T 06-07-2017 CAK95_RS23730 9d5810f377fcedcc27528c5759a1ba31 505 Pfam PF02530 Porin subfamily 55 468 1.3E-66 T 06-07-2017 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 CAK95_RS13880 2570a931ffafb72bea389453ac580062 313 SUPERFAMILY SSF51569 3 307 3.56E-67 T 06-07-2017 CAK95_RS13880 2570a931ffafb72bea389453ac580062 313 SMART SM01130 4 306 2.6E-63 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS13880 2570a931ffafb72bea389453ac580062 313 Gene3D G3DSA:3.20.20.70 5 310 2.9E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS13880 2570a931ffafb72bea389453ac580062 313 Pfam PF00701 Dihydrodipicolinate synthetase family 5 288 1.7E-44 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS13880 2570a931ffafb72bea389453ac580062 313 PIRSF PIRSF001365 1 313 6.4E-59 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 183 236 3.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 SUPERFAMILY SSF46894 173 244 1.33E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 SUPERFAMILY SSF75516 14 173 6.41E-28 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 Pfam PF03472 Autoinducer binding domain 26 162 7.9E-22 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 Gene3D G3DSA:1.10.10.10 187 244 6.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 Gene3D G3DSA:3.30.450.80 13 186 4.8E-27 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 SMART SM00421 181 238 4.8E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 198 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 226 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03680 48ab0e5655a75bc081f3d1c20e26669b 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 214 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS24940 39ec66ac0bfe1933664c4e0497ae77df 231 SUPERFAMILY SSF52540 3 226 1.18E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24940 39ec66ac0bfe1933664c4e0497ae77df 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS24940 39ec66ac0bfe1933664c4e0497ae77df 231 SMART SM00382 32 222 6.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS24940 39ec66ac0bfe1933664c4e0497ae77df 231 Pfam PF00005 ABC transporter 23 174 1.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS24940 39ec66ac0bfe1933664c4e0497ae77df 231 Gene3D G3DSA:3.40.50.300 2 225 6.2E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06850 9ba2e1a6b7ce0ff46aa829610880ba0a 152 Pfam PF07475 HPr Serine kinase C-terminal domain 5 81 1.6E-12 T 06-07-2017 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CAK95_RS06850 9ba2e1a6b7ce0ff46aa829610880ba0a 152 SUPERFAMILY SSF53795 3 96 1.13E-15 T 06-07-2017 CAK95_RS06850 9ba2e1a6b7ce0ff46aa829610880ba0a 152 Gene3D G3DSA:3.40.50.300 4 138 3.7E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01095 0f158ccf7b7bc7bd21b4bd664d0c1514 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 6.1E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01095 0f158ccf7b7bc7bd21b4bd664d0c1514 321 PIRSF PIRSF017082 1 321 1.3E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01095 0f158ccf7b7bc7bd21b4bd664d0c1514 321 SUPERFAMILY SSF53850 111 282 7.42E-12 T 06-07-2017 CAK95_RS26475 4e564debde4c931041659b2c98dd2d24 112 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 99 2.0E-45 T 06-07-2017 IPR004480 Monothiol glutaredoxin-related CAK95_RS26475 4e564debde4c931041659b2c98dd2d24 112 SUPERFAMILY SSF52833 2 102 4.28E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS26475 4e564debde4c931041659b2c98dd2d24 112 PIRSF PIRSF005894 1 107 6.5E-50 T 06-07-2017 IPR014434 Monothiol glutaredoxin CAK95_RS26475 4e564debde4c931041659b2c98dd2d24 112 Gene3D G3DSA:3.40.30.10 7 99 1.1E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS26475 4e564debde4c931041659b2c98dd2d24 112 Pfam PF00462 Glutaredoxin 16 80 1.1E-17 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 4 86 3.0E-14 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 105 8.6E-18 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 47 61 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 SUPERFAMILY SSF54211 2 106 9.36E-25 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 108 13.505 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 Pfam PF00825 Ribonuclease P 2 104 6.9E-23 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK95_RS12195 7891b69b926bb7f48aca4078cc788b1e 119 Gene3D G3DSA:3.30.230.10 1 109 2.2E-29 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Gene3D G3DSA:2.30.38.10 319 394 1.6E-25 T 06-07-2017 CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 487 9.3E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Pfam PF00501 AMP-binding enzyme 14 403 8.1E-101 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 SUPERFAMILY SSF56801 11 498 3.79E-144 T 06-07-2017 CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Gene3D G3DSA:3.40.50.980 12 164 5.0E-36 T 06-07-2017 CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Gene3D G3DSA:3.40.50.980 165 314 1.1E-41 T 06-07-2017 CAK95_RS13690 1fa000c07fc9bf191b44e1e09c6cb800 502 Gene3D G3DSA:3.30.300.30 398 496 1.1E-29 T 06-07-2017 CAK95_RS06995 0ee26e3f4b17bf88dec8e122920f5db9 293 Gene3D G3DSA:3.40.50.1980 148 256 2.3E-11 T 06-07-2017 CAK95_RS06995 0ee26e3f4b17bf88dec8e122920f5db9 293 Pfam PF01497 Periplasmic binding protein 48 247 1.2E-14 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK95_RS06995 0ee26e3f4b17bf88dec8e122920f5db9 293 SUPERFAMILY SSF53807 40 288 7.46E-26 T 06-07-2017 CAK95_RS06995 0ee26e3f4b17bf88dec8e122920f5db9 293 Gene3D G3DSA:3.40.50.1980 41 147 1.8E-8 T 06-07-2017 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 Gene3D G3DSA:1.10.10.10 9 149 2.0E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00410 d264298730665cd9a9e9590030240311 161 Pfam PF01047 MarR family 44 99 1.3E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 7.1E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 7.1E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 7.1E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 SMART SM00347 36 136 2.3E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00410 d264298730665cd9a9e9590030240311 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS00410 d264298730665cd9a9e9590030240311 161 SUPERFAMILY SSF46785 10 151 5.04E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 SMART SM00062 5 225 1.3E-38 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 6 223 1.3E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 Gene3D G3DSA:3.40.190.10 3 91 3.9E-34 T 06-07-2017 CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 Gene3D G3DSA:3.40.190.10 184 225 3.9E-34 T 06-07-2017 CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 Gene3D G3DSA:3.40.190.10 101 172 4.3E-12 T 06-07-2017 CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 SUPERFAMILY SSF53850 2 224 2.65E-52 T 06-07-2017 CAK95_RS21150 bb8553d123ad406bfe91cfec93d7cecd 230 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 28 41 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAK95_RS01570 aec9a097fd84fcd22df8395495540d05 200 Gene3D G3DSA:3.40.50.720 1 185 2.8E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01570 aec9a097fd84fcd22df8395495540d05 200 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 9.2E-19 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAK95_RS01570 aec9a097fd84fcd22df8395495540d05 200 SUPERFAMILY SSF51735 1 185 6.35E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 245 367 3.6E-13 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 Gene3D G3DSA:2.40.50.100 290 323 3.4E-15 T 06-07-2017 CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 Gene3D G3DSA:2.40.50.100 127 159 3.4E-15 T 06-07-2017 CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 Pfam PF13533 Biotin-lipoyl like 127 174 2.2E-18 T 06-07-2017 CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 SUPERFAMILY SSF111369 241 374 2.35E-10 T 06-07-2017 CAK95_RS15430 9c7be2b875193f5e48864ed27b3dabae 433 SUPERFAMILY SSF111369 125 211 9.29E-12 T 06-07-2017 CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 SUPERFAMILY SSF52540 24 257 2.99E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 Gene3D G3DSA:3.40.50.300 23 258 1.7E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 Pfam PF00005 ABC transporter 39 187 2.1E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 PIRSF PIRSF039085 20 263 8.3E-107 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAK95_RS01245 2b5a6129fa251e30721b4e71e210ea8c 263 SMART SM00382 48 235 1.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26685 9f83a858a3de3b0d1a8b9f36defaa656 344 SUPERFAMILY SSF51197 56 312 1.37E-27 T 06-07-2017 CAK95_RS26685 9f83a858a3de3b0d1a8b9f36defaa656 344 Gene3D G3DSA:2.60.120.620 58 211 4.4E-13 T 06-07-2017 CAK95_RS26685 9f83a858a3de3b0d1a8b9f36defaa656 344 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 68 229 1.0E-10 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK95_RS28145 285e2ccf2d62b11db698e9fba545f712 317 SUPERFAMILY SSF56925 72 231 8.63E-20 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS28145 285e2ccf2d62b11db698e9fba545f712 317 SUPERFAMILY SSF56925 263 317 8.63E-20 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS28145 285e2ccf2d62b11db698e9fba545f712 317 Gene3D G3DSA:2.40.160.20 72 233 5.2E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS28145 285e2ccf2d62b11db698e9fba545f712 317 Gene3D G3DSA:2.40.160.20 265 317 5.2E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS28145 285e2ccf2d62b11db698e9fba545f712 317 Pfam PF13505 Outer membrane protein beta-barrel domain 66 317 3.0E-12 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 SUPERFAMILY SSF51735 3 246 4.89E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 Gene3D G3DSA:3.40.50.720 3 247 1.9E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 7.5E-65 T 06-07-2017 CAK95_RS27135 df2040399da310b82ab32c1c2b572527 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS16565 4b34aa1054c3ecdb8df75d402bff019d 97 Pfam PF06844 Protein of unknown function (DUF1244) 27 93 2.0E-38 T 06-07-2017 IPR023163 SMc04008-like domain CAK95_RS16565 4b34aa1054c3ecdb8df75d402bff019d 97 SUPERFAMILY SSF158757 1 77 1.01E-38 T 06-07-2017 IPR023163 SMc04008-like domain CAK95_RS16565 4b34aa1054c3ecdb8df75d402bff019d 97 Gene3D G3DSA:1.10.3340.10 1 84 3.5E-44 T 06-07-2017 IPR023163 SMc04008-like domain CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SUPERFAMILY SSF50249 36 197 2.86E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:3.30.56.20 404 476 1.3E-22 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:3.30.70.380 713 804 1.5E-28 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:2.40.50.140 45 226 7.3E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 804 3.0E-209 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SMART SM00874 404 472 4.9E-24 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SMART SM00873 216 388 3.2E-86 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:3.30.56.10 1 38 4.5E-24 T 06-07-2017 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:3.50.40.10 227 396 4.7E-81 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SUPERFAMILY SSF46955 405 476 1.74E-16 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 798 40.338 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Pfam PF03484 tRNA synthetase B5 domain 407 471 2.5E-16 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SUPERFAMILY SSF56037 213 399 1.31E-72 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SMART SM00896 711 804 5.1E-41 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Gene3D G3DSA:3.30.930.10 491 696 2.3E-52 T 06-07-2017 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SUPERFAMILY SSF54991 708 804 1.83E-27 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Pfam PF03483 B3/4 domain 217 388 8.1E-65 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 SUPERFAMILY SSF55681 468 695 7.95E-38 T 06-07-2017 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 711 804 7.4E-26 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK95_RS09015 c52ea39cc56f0c125394a7c389ca71f5 805 Pfam PF01588 Putative tRNA binding domain 46 146 9.2E-23 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CAK95_RS21550 2a8be7a5497126666c01f5e4ec6b1784 145 Pfam PF00106 short chain dehydrogenase 11 99 4.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21550 2a8be7a5497126666c01f5e4ec6b1784 145 Gene3D G3DSA:3.40.50.720 5 99 7.5E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21550 2a8be7a5497126666c01f5e4ec6b1784 145 SUPERFAMILY SSF51735 9 110 1.62E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 SUPERFAMILY SSF51246 317 365 4.0E-13 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 Gene3D G3DSA:3.30.470.20 189 361 1.8E-60 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 Gene3D G3DSA:3.30.1490.20 125 188 1.0E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 SUPERFAMILY SSF52440 6 107 4.75E-26 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 Pfam PF02222 ATP-grasp domain 119 291 9.9E-56 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 365 41.195 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 363 1.5E-115 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 Gene3D G3DSA:3.40.50.20 10 117 9.6E-31 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS04375 857c8996a4bc2296280a1447d06aca5b 367 SUPERFAMILY SSF56059 110 310 2.12E-63 T 06-07-2017 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 SUPERFAMILY SSF53671 27 332 7.86E-67 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 287 296 2.2E-17 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 71 90 2.2E-17 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 2.2E-17 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 157 168 2.2E-17 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 Gene3D G3DSA:3.40.50.1370 167 318 9.7E-30 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 29 169 9.7E-36 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 177 328 2.0E-12 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 Gene3D G3DSA:3.40.50.1370 28 166 9.7E-40 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 313 327 7.5E-22 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 102 111 7.5E-22 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 61 83 7.5E-22 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 156 173 7.5E-22 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS06010 3d107457241c09dfac650d95868d2dcc 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 296 7.5E-22 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 SUPERFAMILY SSF47446 328 431 1.8E-35 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 1.2E-66 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 SMART SM00382 99 246 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Gene3D G3DSA:1.10.260.30 328 431 3.2E-38 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 SMART SM00963 1 86 6.0E-32 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 5.9E-20 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 SMART SM00962 100 296 1.5E-101 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Pfam PF02978 Signal peptide binding domain 328 427 7.0E-32 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 461 32.232 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 428 8.0E-176 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Gene3D G3DSA:1.20.120.140 2 88 7.9E-32 T 06-07-2017 CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 SUPERFAMILY SSF52540 42 354 5.84E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07645 5d3605831d160f0f5a803c27b8a2ad6a 511 Gene3D G3DSA:3.40.50.300 95 297 6.7E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 Gene3D G3DSA:3.40.30.10 4 90 6.9E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 SUPERFAMILY SSF52833 3 86 1.19E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 213 1.4E-79 T 06-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 SUPERFAMILY SSF47616 82 212 1.25E-31 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 82 8.3E-17 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 Pfam PF14497 Glutathione S-transferase, C-terminal domain 121 196 1.9E-6 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS25480 ec2be46443dec10394cab40688762db6 214 Gene3D G3DSA:1.20.1050.10 91 213 1.7E-49 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Gene3D G3DSA:3.40.50.300 133 303 3.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Pfam PF11638 DnaA N-terminal domain 11 72 2.0E-19 T 06-07-2017 IPR024633 DnaA N-terminal domain CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 ProSitePatterns PS01008 DnaA protein signature. 440 459 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Pfam PF00308 Bacterial dnaA protein 140 362 5.4E-73 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 SMART SM00760 390 459 2.0E-41 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Gene3D G3DSA:1.10.8.60 309 380 1.5E-19 T 06-07-2017 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 13 480 1.9E-147 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Gene3D G3DSA:1.10.1750.10 381 482 1.3E-40 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 SMART SM00382 175 301 4.1E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 SUPERFAMILY SSF52540 139 357 1.05E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 481 28.418 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 391 459 5.1E-31 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 SUPERFAMILY SSF48295 377 481 1.96E-36 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 440 459 1.1E-44 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 253 1.1E-44 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 221 1.1E-44 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 1.1E-44 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK95_RS09455 bf8f10e78a627bea762d37d4e03911db 482 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 272 299 1.1E-44 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 SUPERFAMILY SSF54373 270 360 1.44E-15 T 06-07-2017 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Pfam PF01266 FAD dependent oxidoreductase 2 398 5.9E-58 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Gene3D G3DSA:3.40.50.720 1 96 1.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Gene3D G3DSA:3.40.50.720 194 270 1.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Gene3D G3DSA:3.40.50.720 354 412 1.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 SUPERFAMILY SSF51905 1 54 5.31E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 SUPERFAMILY SSF51905 360 413 5.31E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 SUPERFAMILY SSF51905 107 270 5.31E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Gene3D G3DSA:3.30.9.10 271 353 2.3E-13 T 06-07-2017 CAK95_RS05210 b97acb45dff2a2f0c46762dae5d8da98 418 Gene3D G3DSA:3.30.9.10 135 193 2.3E-13 T 06-07-2017 CAK95_RS24675 2d8252250bcca388c0c2c661abc676ce 151 Gene3D G3DSA:3.10.180.10 2 133 1.8E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS24675 2d8252250bcca388c0c2c661abc676ce 151 SUPERFAMILY SSF54593 1 133 9.53E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS24675 2d8252250bcca388c0c2c661abc676ce 151 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAK95_RS24675 2d8252250bcca388c0c2c661abc676ce 151 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 128 5.0E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 SMART SM00347 43 143 2.8E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 4.1E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 4.1E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 4.1E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 4.1E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 SUPERFAMILY SSF46785 19 154 2.73E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 Pfam PF01047 MarR family 50 108 2.5E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14155 6ef206658a57450287227ae099f1371a 156 Gene3D G3DSA:1.10.10.10 20 153 1.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 Pfam PF00027 Cyclic nucleotide-binding domain 28 111 3.6E-22 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 SUPERFAMILY SSF51206 24 140 4.19E-29 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 Gene3D G3DSA:1.10.10.10 143 208 1.8E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 Pfam PF13545 Crp-like helix-turn-helix domain 146 208 2.4E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 SUPERFAMILY SSF46785 143 205 2.03E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 Gene3D G3DSA:2.60.120.10 25 137 1.1E-27 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS14385 914c6f0b4ce130ed001bb4a386873dce 224 SMART SM00100 9 125 6.0E-19 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 Pfam PF07729 FCD domain 91 210 1.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 SUPERFAMILY SSF48008 87 219 2.12E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 SMART SM00895 91 212 2.3E-12 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 Gene3D G3DSA:1.10.10.10 14 83 1.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 SUPERFAMILY SSF46785 17 85 9.63E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 Gene3D G3DSA:1.20.120.530 84 223 2.0E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 SMART SM00345 23 81 8.6E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS01230 db50a9631c4ccc27d6e38704823b5708 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 4.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 Gene3D G3DSA:2.130.10.120 78 408 2.5E-99 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 SUPERFAMILY SSF50993 3 412 3.4E-91 T 06-07-2017 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 Gene3D G3DSA:3.40.50.1820 420 661 5.5E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 SUPERFAMILY SSF53474 416 658 1.98E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 5 404 3.5E-94 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 448 466 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 502 521 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 532 552 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 609 631 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 591 606 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 474 498 2.9E-42 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK95_RS25700 9524ef0924300e94c3793494d290e857 692 Pfam PF00326 Prolyl oligopeptidase family 463 680 5.0E-63 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK95_RS15075 5194f030a8b3b57c8c61919df45c5e99 184 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 10 170 1.7E-71 T 06-07-2017 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CAK95_RS15075 5194f030a8b3b57c8c61919df45c5e99 184 SUPERFAMILY SSF51182 7 175 1.71E-52 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS15075 5194f030a8b3b57c8c61919df45c5e99 184 Gene3D G3DSA:2.60.120.10 7 114 2.6E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15075 5194f030a8b3b57c8c61919df45c5e99 184 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 6 175 33.759 T 06-07-2017 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CAK95_RS15075 5194f030a8b3b57c8c61919df45c5e99 184 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 8 157 2.8E-51 T 06-07-2017 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 Gene3D G3DSA:3.20.20.70 2 251 1.1E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 Gene3D G3DSA:3.90.1210.10 267 329 3.2E-13 T 06-07-2017 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 Pfam PF08666 SAF domain 279 319 1.2E-4 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 SUPERFAMILY SSF51269 266 328 4.97E-11 T 06-07-2017 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 Pfam PF03102 NeuB family 20 251 2.6E-64 T 06-07-2017 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CAK95_RS17705 6afc29bc6067f9bd67667642f3eaeb84 330 SUPERFAMILY SSF51569 1 254 1.47E-62 T 06-07-2017 CAK95_RS01745 1444b02420bfb7610253b62c9a45128f 290 Gene3D G3DSA:1.25.40.10 47 244 1.2E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS01745 1444b02420bfb7610253b62c9a45128f 290 Pfam PF13525 Outer membrane lipoprotein 47 245 2.9E-52 T 06-07-2017 CAK95_RS01745 1444b02420bfb7610253b62c9a45128f 290 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 24 258 2.3E-85 T 06-07-2017 IPR017689 Outer membrane protein assembly factor BamD CAK95_RS01745 1444b02420bfb7610253b62c9a45128f 290 SUPERFAMILY SSF48452 70 257 5.52E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS01745 1444b02420bfb7610253b62c9a45128f 290 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 21 252 35.726 T 06-07-2017 IPR017689 Outer membrane protein assembly factor BamD CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 SMART SM00876 243 340 2.2E-43 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 243 338 7.2E-19 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 TIGRFAM TIGR00433 bioB: biotin synthase 39 338 1.8E-121 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 SMART SM00729 66 277 1.9E-37 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 SUPERFAMILY SSF102114 28 340 3.66E-91 T 06-07-2017 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 Hamap MF_01694 Biotin synthase [bioB]. 28 341 42.612 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 Pfam PF04055 Radical SAM superfamily 73 227 2.0E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 Gene3D G3DSA:3.20.20.70 28 340 1.7E-101 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS12820 49950c27840fa8c32d8cfbd79df51f70 343 PIRSF PIRSF001619 12 343 1.3E-137 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 144 157 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 399 419 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 566 586 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 609 638 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 248 263 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 742 768 3.5E-54 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 SUPERFAMILY SSF51621 22 915 4.39E-288 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 568 580 - T 06-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 Gene3D G3DSA:1.20.1440.90 277 402 3.1E-23 T 06-07-2017 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 Pfam PF00311 Phosphoenolpyruvate carboxylase 142 915 1.2E-280 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 145 156 - T 06-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS02810 50a9342e208b2a8f7df38a9d94e8283d 915 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 13 915 18.908 T 06-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 Gene3D G3DSA:3.30.43.10 1 51 6.5E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 166 7.0E-44 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 Gene3D G3DSA:3.30.390.50 171 264 5.5E-17 T 06-07-2017 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 SUPERFAMILY SSF55447 171 265 3.92E-18 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 Gene3D G3DSA:3.30.465.10 58 166 8.8E-31 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 263 8.1E-5 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 SUPERFAMILY SSF56176 1 167 1.75E-48 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS20385 86d58117e6f3a727f822ea56c088120b 273 SMART SM01092 171 264 8.0E-21 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS01480 767f15479adfd98f2dd1823b7626cd98 262 SUPERFAMILY SSF56529 4 260 4.58E-65 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS01480 767f15479adfd98f2dd1823b7626cd98 262 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 85 257 2.1E-5 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS01480 767f15479adfd98f2dd1823b7626cd98 262 Gene3D G3DSA:3.90.850.10 1 260 4.7E-74 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS13020 0a116f8e49c08014c3e3055a7f257335 442 Gene3D G3DSA:3.40.50.2300 167 300 4.7E-11 T 06-07-2017 CAK95_RS13020 0a116f8e49c08014c3e3055a7f257335 442 SUPERFAMILY SSF53822 28 403 1.48E-45 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS13020 0a116f8e49c08014c3e3055a7f257335 442 Gene3D G3DSA:3.40.50.2300 301 357 4.0E-16 T 06-07-2017 CAK95_RS13020 0a116f8e49c08014c3e3055a7f257335 442 Gene3D G3DSA:3.40.50.2300 23 152 4.0E-16 T 06-07-2017 CAK95_RS13020 0a116f8e49c08014c3e3055a7f257335 442 Pfam PF13458 Periplasmic binding protein 28 397 2.4E-67 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS23100 9ae98c20ce95f09791c711f2d6083d4e 291 Pfam PF13460 NAD(P)H-binding 6 186 1.1E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23100 9ae98c20ce95f09791c711f2d6083d4e 291 Gene3D G3DSA:3.40.50.720 3 222 7.7E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23100 9ae98c20ce95f09791c711f2d6083d4e 291 SUPERFAMILY SSF51735 3 260 2.14E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20955 625722641af62ce8c7dffdb6203cd3dd 364 Gene3D G3DSA:3.60.110.10 6 309 1.2E-61 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS20955 625722641af62ce8c7dffdb6203cd3dd 364 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 06-07-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CAK95_RS20955 625722641af62ce8c7dffdb6203cd3dd 364 Pfam PF00795 Carbon-nitrogen hydrolase 8 287 5.3E-41 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS20955 625722641af62ce8c7dffdb6203cd3dd 364 SUPERFAMILY SSF56317 6 310 3.14E-65 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 SMART SM00357 37 101 2.5E-7 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 SMART SM00357 129 193 8.9E-11 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 SUPERFAMILY SSF50249 36 100 6.21E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 Pfam PF00313 'Cold-shock' DNA-binding domain 129 191 4.2E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 Pfam PF00313 'Cold-shock' DNA-binding domain 37 94 9.7E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 SUPERFAMILY SSF50249 128 192 3.86E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 Gene3D G3DSA:2.40.50.140 37 98 5.9E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 Gene3D G3DSA:2.40.50.140 131 191 4.7E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 PRINTS PR00050 Cold shock protein signature 74 92 2.9E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 PRINTS PR00050 Cold shock protein signature 38 53 2.9E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS24650 198231a79103b2a81945f84ab2ea87f5 202 PRINTS PR00050 Cold shock protein signature 59 68 2.9E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS22405 3e8b80acaa3dbd0c2785a31636bd1f98 353 Gene3D G3DSA:3.90.226.10 4 200 9.9E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22405 3e8b80acaa3dbd0c2785a31636bd1f98 353 Gene3D G3DSA:3.90.226.10 257 325 9.9E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22405 3e8b80acaa3dbd0c2785a31636bd1f98 353 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 342 5.1E-124 T 06-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CAK95_RS22405 3e8b80acaa3dbd0c2785a31636bd1f98 353 SUPERFAMILY SSF52096 252 328 3.25E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22405 3e8b80acaa3dbd0c2785a31636bd1f98 353 SUPERFAMILY SSF52096 3 189 3.25E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 SUPERFAMILY SSF49503 402 515 2.09E-29 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 SUPERFAMILY SSF49503 181 322 2.84E-30 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 SUPERFAMILY SSF49503 42 176 1.77E-26 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Pfam PF00394 Multicopper oxidase 240 298 6.3E-7 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Pfam PF07732 Multicopper oxidase 62 174 2.3E-25 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Pfam PF07731 Multicopper oxidase 407 515 4.9E-26 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Gene3D G3DSA:2.60.40.420 179 323 4.5E-34 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Gene3D G3DSA:2.60.40.420 39 178 5.2E-28 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 ProSitePatterns PS00080 Multicopper oxidases signature 2. 498 509 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS03560 f9083091ee30ecfb851a69b84a1c3ca2 516 Gene3D G3DSA:2.60.40.420 349 515 9.4E-33 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS27005 46be88e603d8d1fc3428fb99763002f1 158 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 13 140 1.1E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:3.40.50.300 227 275 1.5E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:3.40.50.300 39 144 1.5E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:3.40.50.300 342 387 1.5E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 SUPERFAMILY SSF52540 40 276 7.99E-168 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 SUPERFAMILY SSF52540 343 736 7.99E-168 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:1.10.486.10 490 634 1.6E-47 T 06-07-2017 CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:3.40.50.300 388 489 1.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:3.40.50.300 644 737 1.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Pfam PF00580 UvrD/REP helicase N-terminal domain 43 272 1.8E-54 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Pfam PF00580 UvrD/REP helicase N-terminal domain 341 374 1.1E-9 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Pfam PF13361 UvrD-like helicase C-terminal domain 379 703 1.9E-60 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK95_RS14530 e516ce6b58336a0d6f1c9e456e0562b6 915 Gene3D G3DSA:1.10.10.160 148 226 6.7E-20 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAK95_RS01160 2518388d4159e5e630fe488c1f1f2587 434 PIRSF PIRSF006066 6 434 1.3E-75 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS01160 2518388d4159e5e630fe488c1f1f2587 434 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 430 3.1E-82 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS01160 2518388d4159e5e630fe488c1f1f2587 434 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 425 2.5E-73 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS06740 62360ae71c91321dec1a79ee07ff25a0 245 SUPERFAMILY SSF53448 6 244 1.31E-55 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS06740 62360ae71c91321dec1a79ee07ff25a0 245 Gene3D G3DSA:3.90.550.10 6 245 2.3E-68 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS06740 62360ae71c91321dec1a79ee07ff25a0 245 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 4 244 34.681 T 06-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CAK95_RS06740 62360ae71c91321dec1a79ee07ff25a0 245 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 6 237 4.3E-62 T 06-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CAK95_RS06740 62360ae71c91321dec1a79ee07ff25a0 245 Pfam PF02348 Cytidylyltransferase 8 218 2.8E-41 T 06-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 Gene3D G3DSA:3.40.50.2300 23 151 8.0E-54 T 06-07-2017 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 Gene3D G3DSA:3.40.50.2300 290 355 8.0E-54 T 06-07-2017 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 283 296 1.9E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 1.9E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 27 43 1.9E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 86 1.9E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 SUPERFAMILY SSF53822 26 374 2.32E-95 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS25435 94fd5a4c5f433beba76391444ead9014 390 Pfam PF13458 Periplasmic binding protein 26 369 4.9E-78 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS04840 eed87c1a9231c14a64d0d64dc6f1a7a3 317 Pfam PF16220 Domain of unknown function (DUF4880) 16 57 8.8E-14 T 06-07-2017 IPR032623 FecR, N-terminal CAK95_RS04840 eed87c1a9231c14a64d0d64dc6f1a7a3 317 Pfam PF16344 Domain of unknown function (DUF4974) 218 306 6.8E-9 T 06-07-2017 IPR032508 Protein FecR, C-terminal CAK95_RS04840 eed87c1a9231c14a64d0d64dc6f1a7a3 317 PIRSF PIRSF018266 5 317 2.7E-84 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAK95_RS04840 eed87c1a9231c14a64d0d64dc6f1a7a3 317 Pfam PF04773 FecR protein 111 202 1.0E-21 T 06-07-2017 IPR006860 FecR protein CAK95_RS01885 16c5a983c361e697591196cd8f18165c 268 SMART SM00062 42 261 4.2E-23 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS01885 16c5a983c361e697591196cd8f18165c 268 Gene3D G3DSA:3.40.190.10 147 209 4.2E-8 T 06-07-2017 CAK95_RS01885 16c5a983c361e697591196cd8f18165c 268 SUPERFAMILY SSF53850 43 248 7.65E-36 T 06-07-2017 CAK95_RS01885 16c5a983c361e697591196cd8f18165c 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 235 3.5E-28 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS01885 16c5a983c361e697591196cd8f18165c 268 Gene3D G3DSA:3.40.190.10 22 146 1.0E-18 T 06-07-2017 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 85 99 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Gene3D G3DSA:3.40.50.720 238 393 1.4E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 469 47.845 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 258 275 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SUPERFAMILY SSF51735 236 395 4.83E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SMART SM00997 236 395 2.5E-107 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 469 7.4E-177 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 PIRSF PIRSF001109 1 477 1.4E-185 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Gene3D G3DSA:3.40.50.1480 396 477 4.8E-145 T 06-07-2017 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Gene3D G3DSA:3.40.50.1480 13 237 4.8E-145 T 06-07-2017 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 476 4.7E-145 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SMART SM00996 13 476 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 236 395 2.1E-79 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SUPERFAMILY SSF52283 188 235 7.37E-114 T 06-07-2017 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SUPERFAMILY SSF52283 396 477 7.37E-114 T 06-07-2017 CAK95_RS06885 94e2a6d20cb48a9279ad268b421da93f 477 SUPERFAMILY SSF52283 11 150 7.37E-114 T 06-07-2017 CAK95_RS18555 18892c35b51619cb563756bca9733755 369 SUPERFAMILY SSF51726 11 367 1.44E-77 T 06-07-2017 CAK95_RS18555 18892c35b51619cb563756bca9733755 369 Gene3D G3DSA:3.20.20.210 5 368 3.1E-103 T 06-07-2017 CAK95_RS18555 18892c35b51619cb563756bca9733755 369 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 363 1.2E-14 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Gene3D G3DSA:3.20.20.450 334 572 3.8E-90 T 06-07-2017 IPR001633 EAL domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Gene3D G3DSA:3.30.450.20 36 149 3.0E-14 T 06-07-2017 CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 39 156 6.6E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SMART SM00267 151 320 4.3E-55 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 314 4.7E-47 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Gene3D G3DSA:3.30.70.270 163 324 7.1E-54 T 06-07-2017 CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SMART SM00091 36 101 8.1E-6 T 06-07-2017 IPR000014 PAS domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SUPERFAMILY SSF141868 335 573 1.57E-86 T 06-07-2017 IPR001633 EAL domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SUPERFAMILY SSF55785 36 149 3.49E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SUPERFAMILY SSF55073 167 322 8.63E-47 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Pfam PF08448 PAS fold 43 153 7.4E-9 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 Pfam PF00563 EAL domain 337 567 2.7E-74 T 06-07-2017 IPR001633 EAL domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 SMART SM00052 330 572 3.3E-101 T 06-07-2017 IPR001633 EAL domain CAK95_RS12580 c83a17541d4a210ed116cd18ab6fffaa 590 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 160 316 1.4E-43 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Gene3D G3DSA:3.90.226.10 4 281 6.5E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Gene3D G3DSA:1.10.1040.10 481 566 3.9E-17 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 299 475 2.0E-60 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 SUPERFAMILY SSF52096 4 290 3.32E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 479 565 4.1E-20 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 601 687 6.1E-10 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 92 112 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Gene3D G3DSA:3.40.50.720 292 480 1.2E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 194 7.2E-45 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 SUPERFAMILY SSF48179 597 689 2.64E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 SUPERFAMILY SSF51735 295 475 2.02E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 Gene3D G3DSA:1.10.1040.10 606 689 2.0E-19 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS17190 8786604fdf26bd69e92046504598f4a6 696 SUPERFAMILY SSF48179 479 574 8.33E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Gene3D G3DSA:1.20.140.10 219 383 9.3E-57 T 06-07-2017 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Gene3D G3DSA:1.10.540.10 4 114 4.6E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Gene3D G3DSA:2.40.110.10 118 218 1.3E-32 T 06-07-2017 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.2E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 9.5E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 SUPERFAMILY SSF47203 227 382 3.54E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 SUPERFAMILY SSF56645 3 239 1.31E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 216 4.9E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS10220 95d1d8effa990cbb43302bed5f18fb15 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 120 132 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 SUPERFAMILY SSF51735 132 312 4.51E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 Gene3D G3DSA:3.40.50.720 162 285 4.5E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 SUPERFAMILY SSF50129 2 161 8.52E-38 T 06-07-2017 IPR011032 GroES-like CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 Pfam PF00107 Zinc-binding dehydrogenase 167 300 9.0E-31 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 Gene3D G3DSA:3.90.180.10 3 161 3.5E-42 T 06-07-2017 IPR011032 GroES-like CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 97 7.3E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS05005 ab065a0821181e5ab41b6bfbf9992c63 338 SMART SM00829 14 336 1.0E-45 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 SUPERFAMILY SSF47090 89 144 6.67E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 Pfam PF01471 Putative peptidoglycan binding domain 90 143 3.7E-6 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 Pfam PF13365 Trypsin-like peptidase domain 301 427 5.0E-7 T 06-07-2017 CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 Gene3D G3DSA:1.10.101.10 93 150 4.4E-9 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 SUPERFAMILY SSF50494 294 447 9.27E-13 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS09070 60be1dcc4212729f172e914ddf87e8c1 475 Gene3D G3DSA:2.40.10.10 282 362 2.4E-6 T 06-07-2017 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 Gene3D G3DSA:3.40.50.620 2 163 7.4E-45 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 163 4.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 164 30.713 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 Pfam PF01467 Cytidylyltransferase-like 6 139 1.7E-14 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 58 3.6E-17 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 118 140 1.2E-27 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.2E-27 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.2E-27 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 91 107 1.2E-27 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK95_RS22255 734e04c5a7bfdeabbc991bd25c1999a1 165 SUPERFAMILY SSF52374 3 161 4.29E-37 T 06-07-2017 CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 Gene3D G3DSA:3.40.50.300 2 234 1.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 SMART SM00382 27 222 2.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 Pfam PF00005 ABC transporter 20 173 1.7E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 2 241 5.4E-90 T 06-07-2017 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CAK95_RS23720 215d3d08821f4d92eee4d05fee273969 251 SUPERFAMILY SSF52540 2 233 5.21E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 300 320 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 364 380 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 245 273 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 223 238 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 169 182 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PRINTS PR00143 Citrate synthase signature 384 398 4.3E-56 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 Pfam PF00285 Citrate synthase, C-terminal domain 50 416 1.8E-135 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 ProSitePatterns PS00480 Citrate synthase signature. 307 319 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 SUPERFAMILY SSF48256 9 433 2.62E-168 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 Gene3D G3DSA:1.10.230.10 285 378 1.7E-42 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 Gene3D G3DSA:1.10.580.10 56 284 2.6E-99 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 427 8.0E-244 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CAK95_RS23045 baf2bc4768711b1fb8bd9d1bf55b2cc1 435 PIRSF PIRSF001369 41 434 1.0E-169 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type CAK95_RS03040 c755284f119ebc7bb3750600e12d22d2 846 Pfam PF05272 Virulence-associated protein E 526 718 4.4E-67 T 06-07-2017 IPR007936 Virulence-associated E CAK95_RS03040 c755284f119ebc7bb3750600e12d22d2 846 Gene3D G3DSA:3.40.1360.10 231 326 1.1E-4 T 06-07-2017 CAK95_RS03040 c755284f119ebc7bb3750600e12d22d2 846 Pfam PF13362 Toprim domain 235 321 3.6E-24 T 06-07-2017 IPR006171 Toprim domain CAK95_RS02325 9248c99d2df9994c1a14ac578e5830b4 229 SUPERFAMILY SSF54427 94 228 7.01E-28 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS02325 9248c99d2df9994c1a14ac578e5830b4 229 Pfam PF04335 VirB8 protein 23 226 1.1E-70 T 06-07-2017 IPR007430 Bacterial virulence protein VirB8 GO:0016020 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 50 63 4.2E-52 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 65 90 4.2E-52 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 259 282 4.2E-52 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 472 498 4.2E-52 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 24 46 4.2E-52 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 SUPERFAMILY SSF48113 422 722 8.99E-111 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 SUPERFAMILY SSF48113 18 421 2.21E-151 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00458 Haem peroxidase superfamily signature 166 178 5.2E-20 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00458 Haem peroxidase superfamily signature 251 266 5.2E-20 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00458 Haem peroxidase superfamily signature 88 102 5.2E-20 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00458 Haem peroxidase superfamily signature 310 325 5.2E-20 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 PRINTS PR00458 Haem peroxidase superfamily signature 148 165 5.2E-20 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Pfam PF00141 Peroxidase 394 695 7.0E-38 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Pfam PF00141 Peroxidase 75 387 6.0E-49 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.520.10 231 243 4.1E-74 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.520.10 45 198 4.1E-74 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.520.10 424 574 6.0E-65 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.520.10 701 723 6.0E-65 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 ProSitePatterns PS00436 Peroxidases active site signature. 88 99 - T 06-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Hamap MF_01961 Catalase-peroxidase [katG]. 8 723 41.377 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.420.10 244 266 8.9E-45 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.420.10 302 399 8.9E-45 T 06-07-2017 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 12 723 0.0 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 251 261 - T 06-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CAK95_RS09135 5123e1378c3a3542db35c7315dd21447 732 Gene3D G3DSA:1.10.420.10 575 697 9.7E-44 T 06-07-2017 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 372 5.4E-74 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 379 502 2.3E-48 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 9.6E-20 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 509 51.372 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 SUPERFAMILY SSF50615 10 94 1.65E-30 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 SUPERFAMILY SSF52540 96 378 6.25E-102 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Gene3D G3DSA:2.40.30.20 1 92 5.8E-42 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 SUPERFAMILY SSF47917 380 508 4.19E-48 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 363 372 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 PIRSF PIRSF039088 1 509 6.6E-282 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Gene3D G3DSA:3.40.50.300 95 379 1.9E-123 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 508 2.6E-250 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS07385 4a244e535952dbde19aadbda74ac1395 509 Gene3D G3DSA:1.20.150.20 380 508 4.6E-55 T 06-07-2017 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 Pfam PF00085 Thioredoxin 4 104 4.8E-34 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 PRINTS PR00421 Thioredoxin family signature 30 39 2.0E-9 T 06-07-2017 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 PRINTS PR00421 Thioredoxin family signature 22 30 2.0E-9 T 06-07-2017 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 PRINTS PR00421 Thioredoxin family signature 70 81 2.0E-9 T 06-07-2017 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 PIRSF PIRSF000077 1 106 1.1E-43 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 SUPERFAMILY SSF52833 5 105 2.71E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 Gene3D G3DSA:3.40.30.10 3 104 6.2E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11005 f2fc9c7814cb811e27a72a00d69c61c7 106 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 104 4.4E-40 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK95_RS17630 e6b7d79a09a1d971347253986bfc0a81 357 Gene3D G3DSA:3.40.50.2000 142 333 5.1E-43 T 06-07-2017 CAK95_RS17630 e6b7d79a09a1d971347253986bfc0a81 357 Gene3D G3DSA:3.40.50.2000 1 134 2.0E-21 T 06-07-2017 CAK95_RS17630 e6b7d79a09a1d971347253986bfc0a81 357 SUPERFAMILY SSF53756 1 332 2.51E-59 T 06-07-2017 CAK95_RS17630 e6b7d79a09a1d971347253986bfc0a81 357 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 149 268 1.6E-23 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 PIRSF PIRSF001263 1 148 7.9E-41 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 SUPERFAMILY SSF55234 80 148 3.53E-28 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 SMART SM01116 76 148 4.4E-44 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 Hamap MF_00535 Cyanate hydratase [cynS]. 1 162 81.025 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 Gene3D G3DSA:3.30.1160.10 82 147 7.1E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 SUPERFAMILY SSF47413 1 75 2.08E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 Gene3D G3DSA:1.10.260.40 1 80 3.0E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 PRINTS PR01693 Cyanase signature 133 143 2.9E-19 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 PRINTS PR01693 Cyanase signature 84 98 2.9E-19 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 PRINTS PR01693 Cyanase signature 14 29 2.9E-19 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 PRINTS PR01693 Cyanase signature 102 118 2.9E-19 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 Pfam PF02560 Cyanate lyase C-terminal domain 79 146 1.2E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28325 477b7eb8242de9b21eb64952438ca3f8 162 TIGRFAM TIGR00673 cynS: cyanase 4 148 1.0E-38 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS08060 926629025e1faf7a497fe7479d429398 198 SUPERFAMILY SSF52540 1 192 2.47E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08060 926629025e1faf7a497fe7479d429398 198 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 182 3.5E-36 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK95_RS08060 926629025e1faf7a497fe7479d429398 198 Gene3D G3DSA:3.40.50.300 1 193 3.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08060 926629025e1faf7a497fe7479d429398 198 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 194 25.259 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK95_RS08060 926629025e1faf7a497fe7479d429398 198 Pfam PF01121 Dephospho-CoA kinase 3 173 2.4E-38 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK95_RS28265 f074200cfd4f7da5f0431acf677711c5 70 Gene3D G3DSA:3.30.429.20 1 58 2.7E-8 T 06-07-2017 CAK95_RS28265 f074200cfd4f7da5f0431acf677711c5 70 SUPERFAMILY SSF55331 2 62 1.02E-8 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK95_RS28265 f074200cfd4f7da5f0431acf677711c5 70 Pfam PF01361 Tautomerase enzyme 2 61 5.3E-15 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 SMART SM01130 6 293 1.5E-141 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 Pfam PF00701 Dihydrodipicolinate synthetase family 6 288 3.1E-90 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 PIRSF PIRSF001365 3 296 5.1E-92 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 42 59 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 6 291 62.381 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 Gene3D G3DSA:3.20.20.70 6 295 5.7E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 289 4.2E-94 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 SUPERFAMILY SSF51569 6 293 2.83E-103 T 06-07-2017 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 8.8E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 8.8E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 8.8E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS23745 6a3047a5f52ff1ecea8d69aca7eeedc2 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 8.8E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS13205 05af86ada4a19a37facddb33b796f41f 278 Pfam PF04794 YdjC-like protein 6 270 1.5E-48 T 06-07-2017 IPR006879 Chitooligosaccharide deacetylase ChbG-like CAK95_RS13205 05af86ada4a19a37facddb33b796f41f 278 SUPERFAMILY SSF88713 5 277 1.18E-57 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS13205 05af86ada4a19a37facddb33b796f41f 278 Gene3D G3DSA:3.20.20.370 5 277 1.3E-61 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS12595 0efa460f4da9d41059b8f523a78a02a4 446 Gene3D G3DSA:3.10.350.10 394 441 6.5E-5 T 06-07-2017 IPR018392 LysM domain CAK95_RS12595 0efa460f4da9d41059b8f523a78a02a4 446 SMART SM00257 392 441 4.1E-4 T 06-07-2017 IPR018392 LysM domain CAK95_RS12595 0efa460f4da9d41059b8f523a78a02a4 446 Gene3D G3DSA:2.60.40.10 100 155 3.6E-4 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 Gene3D G3DSA:3.40.190.10 91 178 2.7E-20 T 06-07-2017 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 Gene3D G3DSA:3.40.190.10 179 264 1.7E-21 T 06-07-2017 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 SUPERFAMILY SSF53850 92 298 7.1E-48 T 06-07-2017 CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 Pfam PF03466 LysR substrate binding domain 89 295 1.6E-47 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 SUPERFAMILY SSF46785 3 113 9.99E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 Gene3D G3DSA:1.10.10.10 1 82 4.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27295 a71f4f4c2c83c4d3773a8c81c8a9f372 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.1E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS20400 576dba9d5cf401876f78948998c57246 408 SUPERFAMILY SSF53300 221 349 3.81E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS20400 576dba9d5cf401876f78948998c57246 408 Pfam PF05762 VWA domain containing CoxE-like protein 164 383 4.8E-78 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like CAK95_RS20400 576dba9d5cf401876f78948998c57246 408 Gene3D G3DSA:3.40.50.410 221 326 3.5E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS20400 576dba9d5cf401876f78948998c57246 408 PIRSF PIRSF010256 2 393 5.3E-138 T 06-07-2017 IPR011195 Uncharacterised conserved protein UCP010256 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 Pfam PF03466 LysR substrate binding domain 87 291 5.9E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 Gene3D G3DSA:3.40.190.10 88 175 4.7E-22 T 06-07-2017 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 Gene3D G3DSA:1.10.10.10 1 85 1.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 Gene3D G3DSA:3.40.190.10 176 266 2.6E-27 T 06-07-2017 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 SUPERFAMILY SSF53850 88 293 4.71E-33 T 06-07-2017 CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 SUPERFAMILY SSF46785 1 87 1.38E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14020 bd4bff44646a72e3c0dc11fec6cb091b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.4E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 SUPERFAMILY SSF53448 10 287 2.13E-62 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 SUPERFAMILY SSF51182 193 474 1.11E-76 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 Gene3D G3DSA:2.60.120.10 364 474 1.1E-45 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 10 474 1.6E-186 T 06-07-2017 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 Gene3D G3DSA:3.90.550.10 9 276 2.8E-80 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 Pfam PF01050 Mannose-6-phosphate isomerase 321 470 3.9E-66 T 06-07-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CAK95_RS17765 c27fa9bb70ca20decda64dc9881d74b6 475 Pfam PF00483 Nucleotidyl transferase 12 291 2.0E-55 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK95_RS20190 ff189e0462e3961e57288d7241489fee 244 Gene3D G3DSA:3.40.50.1820 54 116 7.9E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20190 ff189e0462e3961e57288d7241489fee 244 SUPERFAMILY SSF53474 52 138 2.93E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS21270 a7cee5967bc0f409e006b06b10ab7bd9 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.125 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21270 a7cee5967bc0f409e006b06b10ab7bd9 206 Gene3D G3DSA:3.40.1370.10 58 205 9.8E-52 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAK95_RS21270 a7cee5967bc0f409e006b06b10ab7bd9 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 202 3.3E-67 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21270 a7cee5967bc0f409e006b06b10ab7bd9 206 Pfam PF00573 Ribosomal protein L4/L1 family 16 203 8.2E-61 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CAK95_RS21270 a7cee5967bc0f409e006b06b10ab7bd9 206 SUPERFAMILY SSF52166 1 205 4.84E-70 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 SUPERFAMILY SSF63380 233 316 5.2E-14 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 Pfam PF01794 Ferric reductase like transmembrane component 44 177 2.1E-18 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 Gene3D G3DSA:2.40.30.10 241 307 8.2E-12 T 06-07-2017 CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 Pfam PF00970 Oxidoreductase FAD-binding domain 250 317 3.1E-5 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 SUPERFAMILY SSF52343 312 449 3.8E-17 T 06-07-2017 CAK95_RS23405 2cb3a58dcc0b835bc1d60c565c411aca 450 Gene3D G3DSA:3.40.50.80 308 437 9.7E-16 T 06-07-2017 CAK95_RS02200 0c728424c218631ebd5858c01d9384ff 328 Pfam PF09084 NMT1/THI5 like 88 140 2.1E-5 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS02200 0c728424c218631ebd5858c01d9384ff 328 Gene3D G3DSA:3.40.190.10 88 243 1.3E-13 T 06-07-2017 CAK95_RS02200 0c728424c218631ebd5858c01d9384ff 328 SUPERFAMILY SSF53850 6 134 4.04E-33 T 06-07-2017 CAK95_RS02200 0c728424c218631ebd5858c01d9384ff 328 SUPERFAMILY SSF53850 163 318 4.04E-33 T 06-07-2017 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Gene3D G3DSA:3.90.700.10 262 367 1.4E-42 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Gene3D G3DSA:1.20.58.100 451 557 5.2E-36 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Pfam PF00890 FAD binding domain 29 423 2.7E-126 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 SUPERFAMILY SSF56425 255 373 1.38E-41 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 PIRSF PIRSF000171 19 602 1.3E-41 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 SUPERFAMILY SSF46977 470 612 2.62E-49 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 26 612 3.2E-294 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Gene3D G3DSA:4.10.80.40 558 612 5.8E-32 T 06-07-2017 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 SUPERFAMILY SSF51905 377 448 6.28E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 SUPERFAMILY SSF51905 18 278 6.28E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Gene3D G3DSA:3.50.50.60 19 261 5.1E-125 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Gene3D G3DSA:3.50.50.60 369 445 5.1E-125 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 63 72 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 Pfam PF02910 Fumarate reductase flavoprotein C-term 478 612 8.8E-45 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07840 2c28b803d4b4fd61c77ab54b797760fb 612 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 29 612 9.7E-245 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS14845 42a748b58b49413bcc77d9ad5bd8dde8 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS14845 42a748b58b49413bcc77d9ad5bd8dde8 235 Gene3D G3DSA:3.40.50.300 3 227 1.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14845 42a748b58b49413bcc77d9ad5bd8dde8 235 SMART SM00382 31 212 1.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14845 42a748b58b49413bcc77d9ad5bd8dde8 235 SUPERFAMILY SSF52540 5 224 2.77E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14845 42a748b58b49413bcc77d9ad5bd8dde8 235 Pfam PF00005 ABC transporter 24 162 3.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28155 8b5b1aa008c7bdca4825c5aa3cab61ff 287 SUPERFAMILY SSF56925 38 213 1.02E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS28155 8b5b1aa008c7bdca4825c5aa3cab61ff 287 Pfam PF13505 Outer membrane protein beta-barrel domain 13 225 2.8E-18 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS28155 8b5b1aa008c7bdca4825c5aa3cab61ff 287 Gene3D G3DSA:2.40.160.20 40 245 9.5E-31 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 PIRSF PIRSF039085 17 260 4.3E-108 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 SUPERFAMILY SSF52540 21 254 2.66E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 SMART SM00382 45 232 2.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 Gene3D G3DSA:3.40.50.300 20 256 3.4E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS24200 2f4b3b63773e81a302d7367589b56e76 260 Pfam PF00005 ABC transporter 36 184 7.5E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 Pfam PF01430 Hsp33 protein 20 325 2.2E-79 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 Gene3D G3DSA:3.55.30.10 19 279 9.1E-76 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 PIRSF PIRSF005261 10 334 8.4E-81 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 Gene3D G3DSA:3.90.1280.10 280 330 9.5E-19 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 SUPERFAMILY SSF118352 280 331 4.19E-15 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CAK95_RS05845 6694343227a765e9928d36a445bbd381 338 SUPERFAMILY SSF64397 19 288 4.71E-65 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CAK95_RS17455 1a2a8e7704bb29e8b3679dec37fc3af6 412 SUPERFAMILY SSF53822 41 392 4.87E-56 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS17455 1a2a8e7704bb29e8b3679dec37fc3af6 412 Gene3D G3DSA:3.40.50.2300 305 373 4.5E-26 T 06-07-2017 CAK95_RS17455 1a2a8e7704bb29e8b3679dec37fc3af6 412 Gene3D G3DSA:3.40.50.2300 38 160 4.5E-26 T 06-07-2017 CAK95_RS17455 1a2a8e7704bb29e8b3679dec37fc3af6 412 Gene3D G3DSA:3.40.50.2300 178 294 1.1E-12 T 06-07-2017 CAK95_RS17455 1a2a8e7704bb29e8b3679dec37fc3af6 412 Pfam PF13458 Periplasmic binding protein 41 374 3.5E-43 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 461 1.3E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SMART SM00304 184 237 8.7E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SMART SM00304 248 304 53.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SUPERFAMILY SSF47384 221 305 1.12E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SUPERFAMILY SSF158472 184 235 2.22E-8 T 06-07-2017 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 Gene3D G3DSA:1.10.287.130 228 300 1.0E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 Pfam PF00672 HAMP domain 167 233 1.8E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 Gene3D G3DSA:3.30.565.10 309 463 5.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 304 1.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SMART SM00388 238 304 4.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SUPERFAMILY SSF55874 293 466 3.8E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 SMART SM00387 349 465 6.2E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.3E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19190 134c38975ceab921b6f1b912a77ecdea 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.3E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 140 7.8E-21 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 373 473 4.0E-65 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 637 774 4.0E-65 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 SUPERFAMILY SSF54665 3 163 6.67E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 295 370 6.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 129 186 6.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 SUPERFAMILY SSF56003 132 774 2.09E-187 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 158 710 2.1E-160 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.90.1170.50 3 128 5.2E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 SMART SM01008 20 140 2.5E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 187 293 2.1E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18565 30a44348ebec6f960e14c33b68f76aaa 780 Gene3D G3DSA:3.30.365.10 474 636 2.7E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Gene3D G3DSA:1.10.601.10 146 215 4.5E-131 T 06-07-2017 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Gene3D G3DSA:1.10.601.10 11 145 7.7E-4 T 06-07-2017 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Gene3D G3DSA:1.10.601.10 250 526 4.5E-131 T 06-07-2017 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Gene3D G3DSA:1.10.10.10 619 690 2.0E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 453 689 3.0E-120 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 SUPERFAMILY SSF88659 587 689 4.71E-26 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 SUPERFAMILY SSF88946 247 524 4.4E-96 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 SUPERFAMILY SSF88946 146 209 4.4E-96 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 SUPERFAMILY SSF88659 530 603 6.1E-22 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF03979 Sigma-70 factor, region 1.1 33 102 4.8E-22 T 06-07-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF04542 Sigma-70 region 2 457 526 2.0E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 453 678 4.3E-38 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 650 676 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Gene3D G3DSA:1.10.10.10 530 581 2.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 19 690 45.223 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF04545 Sigma-70, region 4 625 678 1.5E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF04546 Sigma-70, non-essential region 171 424 1.4E-45 T 06-07-2017 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 PRINTS PR00046 Major sigma-70 factor signature 481 494 6.9E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 PRINTS PR00046 Major sigma-70 factor signature 629 641 6.9E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 PRINTS PR00046 Major sigma-70 factor signature 505 513 6.9E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 PRINTS PR00046 Major sigma-70 factor signature 650 665 6.9E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 PRINTS PR00046 Major sigma-70 factor signature 665 676 6.9E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF04539 Sigma-70 region 3 536 611 7.5E-30 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 481 494 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS13960 d7b1b3b74978ca281032b52a90983dfb 691 Pfam PF00140 Sigma-70 factor, region 1.2 129 162 4.5E-14 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 646 0.0 T 06-07-2017 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 502 8.9E-137 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 Gene3D G3DSA:1.20.210.10 40 587 6.2E-182 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 279 333 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 SUPERFAMILY SSF81442 43 558 5.89E-173 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 410 429 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 400 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 226 245 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 460 481 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 119 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 123 147 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 368 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 338 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 197 215 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 277 298 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00875 f0921998dac750eef598ce55b54e8896 677 PRINTS PR01165 Cytochrome c oxidase subunit I signature 165 177 1.1E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS02900 42c97dc4ee00f256ecb5f10b5a704258 69 Pfam PF03459 TOBE domain 4 66 2.9E-18 T 06-07-2017 IPR005116 Transport-associated OB, type 1 CAK95_RS02900 42c97dc4ee00f256ecb5f10b5a704258 69 Gene3D G3DSA:2.40.50.100 1 69 1.3E-26 T 06-07-2017 CAK95_RS02900 42c97dc4ee00f256ecb5f10b5a704258 69 SUPERFAMILY SSF50331 1 69 6.07E-22 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS02900 42c97dc4ee00f256ecb5f10b5a704258 69 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 4.2E-25 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 Gene3D G3DSA:1.10.10.10 16 85 3.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 Pfam PF07729 FCD domain 94 216 2.0E-28 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 SUPERFAMILY SSF48008 91 223 2.62E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 SMART SM00895 94 218 7.3E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 84 9.2E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 SMART SM00345 26 84 2.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 Gene3D G3DSA:1.20.120.530 90 227 8.8E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04775 7d18d2bed248c6245c49518dc531a642 231 SUPERFAMILY SSF46785 18 107 1.82E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 5.5E-18 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 Gene3D G3DSA:1.20.58.110 1 86 4.9E-23 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 SUPERFAMILY SSF46992 3 86 7.98E-23 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.342 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 Pfam PF01649 Ribosomal protein S20 2 83 7.4E-21 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09465 358cc1067b2014895be218b833a1dac2 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 6.0E-19 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS08460 cb421d4fb8de9704e733f005735f3776 138 Gene3D G3DSA:3.10.590.10 1 135 7.6E-29 T 06-07-2017 IPR002740 EVE domain CAK95_RS08460 cb421d4fb8de9704e733f005735f3776 138 Pfam PF01878 EVE domain 2 135 1.1E-45 T 06-07-2017 IPR002740 EVE domain CAK95_RS08460 cb421d4fb8de9704e733f005735f3776 138 SUPERFAMILY SSF88697 1 137 9.94E-54 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 SUPERFAMILY SSF48029 143 350 2.09E-60 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 33 49 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 141 164 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 298 324 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 221 246 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 62 88 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PRINTS PR00954 Flagellar motor switch protein FliG signature 274 294 5.1E-57 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Pfam PF14842 FliG N-terminal domain 32 134 2.5E-21 T 06-07-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Gene3D G3DSA:1.10.220.30 131 216 8.0E-26 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Gene3D G3DSA:1.10.220.30 35 98 3.2E-9 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 SUPERFAMILY SSF48029 34 140 2.22E-18 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Pfam PF14841 FliG middle domain 143 215 3.4E-25 T 06-07-2017 IPR032779 Flagellar motor switch protein FliG, middle domain CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Pfam PF01706 FliG C-terminal domain 244 350 9.8E-37 T 06-07-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 Gene3D G3DSA:1.10.220.30 223 357 2.3E-38 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 30 359 4.3E-74 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS15345 ae8e63822bd779f9d3b17ae00e8936af 361 PIRSF PIRSF003161 27 360 2.7E-112 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 Gene3D G3DSA:3.40.50.150 110 259 2.0E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 Gene3D G3DSA:3.40.50.300 504 658 2.4E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 Pfam PF13872 P-loop containing NTP hydrolase pore-1 417 741 4.8E-118 T 06-07-2017 CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 Pfam PF13871 C-terminal domain on Strawberry notch homologue 912 1168 3.2E-85 T 06-07-2017 IPR026937 Strawberry notch, helicase C domain CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 SUPERFAMILY SSF52540 412 696 8.69E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02575 31255a29600dcade5d79003861e7390b 1446 SUPERFAMILY SSF53335 120 308 2.36E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.5E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.5E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 SMART SM00345 17 76 4.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 SUPERFAMILY SSF48008 98 230 2.17E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 Pfam PF07729 FCD domain 100 223 1.0E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 SMART SM00895 100 225 4.9E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 Gene3D G3DSA:1.10.10.10 19 81 2.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 76 3.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 Gene3D G3DSA:1.20.120.530 99 230 3.7E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS23990 bbbd51a53de57da7e9974b1f5956e2fc 233 SUPERFAMILY SSF46785 11 80 6.45E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 SUPERFAMILY SSF51206 43 180 2.49E-23 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 Gene3D G3DSA:2.60.120.10 40 186 9.7E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 Pfam PF00027 Cyclic nucleotide-binding domain 69 150 4.8E-8 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 SMART SM00419 205 253 3.5E-17 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 SMART SM00100 50 165 3.0E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 227 242 1.7E-10 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 211 227 1.7E-10 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 SUPERFAMILY SSF46785 183 261 6.09E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 Gene3D G3DSA:1.10.10.10 187 261 9.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11175 949fb11a8bb984883e9f64ddd0728cc2 262 Pfam PF13545 Crp-like helix-turn-helix domain 185 260 2.3E-16 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS24460 48b1d6489496af6382f784a217dbded0 441 Pfam PF05065 Phage capsid family 151 438 2.1E-84 T 06-07-2017 IPR024455 Phage capsid CAK95_RS24460 48b1d6489496af6382f784a217dbded0 441 SUPERFAMILY SSF56563 144 439 9.55E-73 T 06-07-2017 CAK95_RS24460 48b1d6489496af6382f784a217dbded0 441 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 41 438 5.6E-114 T 06-07-2017 IPR006444 Phage major capsid protein, HK97 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Gene3D G3DSA:3.40.50.980 32 205 9.2E-23 T 06-07-2017 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Gene3D G3DSA:3.40.50.980 206 359 1.8E-24 T 06-07-2017 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Gene3D G3DSA:3.30.300.30 442 546 1.3E-24 T 06-07-2017 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 SUPERFAMILY SSF56801 26 543 1.7E-108 T 06-07-2017 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Gene3D G3DSA:2.30.38.10 361 426 3.6E-18 T 06-07-2017 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Pfam PF00501 AMP-binding enzyme 37 447 2.4E-58 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS01000 808d97bb1777f41d93b034678f068719 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 2.4E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.1E-25 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 PIRSF PIRSF002599 1 67 9.9E-23 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 SMART SM00357 3 67 8.2E-25 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 SUPERFAMILY SSF50249 1 65 3.43E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK95_RS25755 59d23dd6a21a54bdbd717685cfdb2d89 67 Gene3D G3DSA:2.40.50.140 1 66 4.8E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 Gene3D G3DSA:3.40.190.10 177 260 5.6E-17 T 06-07-2017 CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 SUPERFAMILY SSF53850 72 302 3.41E-52 T 06-07-2017 CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 300 6.7E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 SMART SM00062 75 303 2.8E-45 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 Gene3D G3DSA:3.40.190.10 262 301 2.2E-33 T 06-07-2017 CAK95_RS05680 056b8b550ff13f2d213cddd8ef6ae952 305 Gene3D G3DSA:3.40.190.10 75 161 2.2E-33 T 06-07-2017 CAK95_RS08345 026dfa4d62d1d91976fb56317ce477c7 150 SUPERFAMILY SSF55298 16 148 5.97E-29 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS08345 026dfa4d62d1d91976fb56317ce477c7 150 Gene3D G3DSA:3.30.1330.40 17 148 3.0E-31 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS08345 026dfa4d62d1d91976fb56317ce477c7 150 Pfam PF01042 Endoribonuclease L-PSP 27 146 1.4E-21 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS27475 72cdf105073250a954429b7e865a111e 157 SUPERFAMILY SSF47413 30 101 3.49E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27475 72cdf105073250a954429b7e865a111e 157 Gene3D G3DSA:1.10.260.40 37 99 5.3E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27475 72cdf105073250a954429b7e865a111e 157 Pfam PF01381 Helix-turn-helix 42 93 1.3E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS27475 72cdf105073250a954429b7e865a111e 157 SMART SM00530 40 95 1.2E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 345 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 21 43 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 345 361 3.3E-36 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 Pfam PF01494 FAD binding domain 21 356 3.1E-58 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 SUPERFAMILY SSF51905 21 190 5.52E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 SUPERFAMILY SSF51905 281 393 5.52E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 Gene3D G3DSA:3.30.9.10 182 287 5.0E-10 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 Gene3D G3DSA:3.30.9.10 342 372 5.0E-10 T 06-07-2017 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 Gene3D G3DSA:3.50.50.60 20 181 6.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20020 d71134f18d1fbb1b8de3bd1c7b6fe93f 526 Gene3D G3DSA:3.50.50.60 292 332 6.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 SUPERFAMILY SSF52540 450 648 3.18E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 SMART SM00490 503 586 4.1E-17 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Pfam PF17191 RecG wedge domain 16 181 9.6E-10 T 06-07-2017 IPR033454 RecG, wedge domain CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Gene3D G3DSA:3.40.50.300 259 452 1.6E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 SMART SM00487 268 458 1.5E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Pfam PF00270 DEAD/DEAH box helicase 294 428 5.4E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Gene3D G3DSA:3.40.50.300 453 635 7.6E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 SUPERFAMILY SSF52540 186 451 1.22E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 SUPERFAMILY SSF50249 9 182 2.91E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Gene3D G3DSA:2.40.50.140 53 142 4.3E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS23635 590218c0d7a1a2a0b56e44c18ac8e6bd 699 Pfam PF00271 Helicase conserved C-terminal domain 476 585 5.0E-17 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS14815 83caf8c70902b37bdf88fa7acd50e4aa 397 Gene3D G3DSA:3.40.190.10 83 165 2.0E-19 T 06-07-2017 CAK95_RS14815 83caf8c70902b37bdf88fa7acd50e4aa 397 Gene3D G3DSA:3.40.190.10 306 383 2.0E-19 T 06-07-2017 CAK95_RS14815 83caf8c70902b37bdf88fa7acd50e4aa 397 Gene3D G3DSA:3.40.190.10 186 288 9.7E-5 T 06-07-2017 CAK95_RS14815 83caf8c70902b37bdf88fa7acd50e4aa 397 Pfam PF16868 NMT1-like family 97 382 5.5E-17 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS14815 83caf8c70902b37bdf88fa7acd50e4aa 397 SUPERFAMILY SSF53850 84 383 7.22E-27 T 06-07-2017 CAK95_RS14725 0aa94161c223a704bf86334346ae0ac1 258 Gene3D G3DSA:3.40.50.300 1 239 3.2E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14725 0aa94161c223a704bf86334346ae0ac1 258 SMART SM00382 28 215 9.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14725 0aa94161c223a704bf86334346ae0ac1 258 Pfam PF00005 ABC transporter 19 165 8.1E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14725 0aa94161c223a704bf86334346ae0ac1 258 SUPERFAMILY SSF52540 1 241 5.32E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14725 0aa94161c223a704bf86334346ae0ac1 258 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 SUPERFAMILY SSF52283 6 137 7.44E-17 T 06-07-2017 CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 206 228 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 157 185 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 296 7.0E-55 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 Gene3D G3DSA:3.40.50.720 122 297 7.6E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 SUPERFAMILY SSF51735 112 297 1.37E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 328 1.6E-17 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS02195 91d732c6edbf9d712449c90071828051 352 Gene3D G3DSA:3.40.50.720 6 121 2.2E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15055 e68c8f5448e71b6e9628d177d5a2f349 204 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 13 192 2.6E-75 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAK95_RS15055 e68c8f5448e71b6e9628d177d5a2f349 204 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 11 194 37.275 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAK95_RS15055 e68c8f5448e71b6e9628d177d5a2f349 204 Pfam PF02441 Flavoprotein 13 135 6.5E-27 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS15055 e68c8f5448e71b6e9628d177d5a2f349 204 SUPERFAMILY SSF52507 13 194 2.75E-61 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS15055 e68c8f5448e71b6e9628d177d5a2f349 204 Gene3D G3DSA:3.40.50.1950 13 195 1.3E-78 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 SUPERFAMILY SSF56059 116 332 1.03E-64 T 06-07-2017 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 SUPERFAMILY SSF51230 568 644 1.7E-17 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 327 2.2E-72 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Pfam PF02785 Biotin carboxylase C-terminal domain 341 447 2.9E-38 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 SUPERFAMILY SSF52440 1 113 3.67E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Gene3D G3DSA:3.30.1490.20 130 202 7.4E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Gene3D G3DSA:3.40.50.20 1 129 3.4E-51 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Pfam PF00364 Biotin-requiring enzyme 577 642 1.1E-13 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Gene3D G3DSA:3.30.470.20 204 452 3.8E-99 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 SUPERFAMILY SSF51246 336 452 3.66E-41 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 SMART SM00878 341 447 8.5E-60 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.7E-43 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21885 2f0675288f295350be0461752ffda41a 651 Gene3D G3DSA:2.40.50.100 572 644 2.2E-19 T 06-07-2017 CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 Gene3D G3DSA:3.40.50.720 2 244 6.2E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 SUPERFAMILY SSF51735 6 245 2.86E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09945 03e6c57299f573530ac133194aef5ab8 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 1.0E-54 T 06-07-2017 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 SMART SM01092 186 286 3.3E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 Gene3D G3DSA:3.30.465.10 60 177 1.6E-29 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 SUPERFAMILY SSF56176 6 177 2.48E-38 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 Gene3D G3DSA:3.30.390.50 184 291 8.8E-21 T 06-07-2017 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 Gene3D G3DSA:3.30.43.10 6 43 5.6E-6 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 7 177 2.7E-38 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 187 283 2.9E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS10070 e0c7b5b6d2ef41d25516da44fcc07e68 306 SUPERFAMILY SSF55447 188 289 1.16E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF56784 539 787 8.25E-60 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF56784 480 500 8.25E-60 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF81653 283 380 3.4E-25 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Gene3D G3DSA:2.70.150.10 208 380 1.3E-27 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 206 790 9.6E-191 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 496 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 638 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 617 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 704 716 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 700 5.0E-30 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 403 417 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 269 287 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 191 210 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 465 480 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 754 768 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 249 268 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 PRINTS PR00943 Copper-transporting ATPase signature 658 675 5.3E-13 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SMART SM00746 39 77 1.8E-9 T 06-07-2017 IPR011017 TRASH domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Pfam PF00122 E1-E2 ATPase 250 473 4.7E-65 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 187 791 1.5E-181 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 478 695 1.9E-45 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 251 761 1.9E-87 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Gene3D G3DSA:3.40.50.1000 609 749 3.5E-56 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Gene3D G3DSA:3.40.50.1000 453 495 3.5E-56 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF47240 24 91 5.95E-10 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF81665 247 283 3.53E-12 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF81665 381 476 3.53E-12 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 SUPERFAMILY SSF81665 730 752 3.53E-12 T 06-07-2017 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Gene3D G3DSA:3.40.1110.10 496 608 3.7E-25 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 Pfam PF04945 YHS domain 37 82 1.9E-18 T 06-07-2017 IPR007029 YHS domain CAK95_RS19705 a0e24892940db05bdb4b0b1226d97c39 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 484 490 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Gene3D G3DSA:3.40.50.1220 218 368 5.6E-18 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 225 308 6.2E-11 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 SUPERFAMILY SSF52467 186 368 1.21E-17 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 SUPERFAMILY SSF52518 393 586 3.22E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Gene3D G3DSA:3.40.50.970 390 580 2.9E-31 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 SUPERFAMILY SSF52518 27 211 8.83E-35 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 426 576 6.5E-20 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 28 202 2.5E-36 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS24730 1beadacb49c45aa65a12092771f606e7 595 Gene3D G3DSA:3.40.50.970 28 205 5.6E-38 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 SMART SM00267 207 378 2.4E-48 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 SUPERFAMILY SSF55073 223 380 2.67E-41 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 SMART SM00052 388 631 5.4E-99 T 06-07-2017 IPR001633 EAL domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 Pfam PF00990 Diguanylate cyclase, GGDEF domain 218 373 6.0E-39 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 Pfam PF00563 EAL domain 394 626 1.2E-71 T 06-07-2017 IPR001633 EAL domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 377 1.6E-33 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 SUPERFAMILY SSF141868 393 639 4.71E-83 T 06-07-2017 IPR001633 EAL domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 Gene3D G3DSA:3.20.20.450 392 638 9.0E-86 T 06-07-2017 IPR001633 EAL domain CAK95_RS06015 f55023e0b7181b306b61566f3bb443cc 667 Gene3D G3DSA:3.30.70.270 220 384 1.1E-46 T 06-07-2017 CAK95_RS24835 057f82e3c4ed1ab728bbf819a8bec5fb 335 Pfam PF00753 Metallo-beta-lactamase superfamily 102 299 8.0E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24835 057f82e3c4ed1ab728bbf819a8bec5fb 335 Gene3D G3DSA:3.60.15.10 38 325 3.9E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24835 057f82e3c4ed1ab728bbf819a8bec5fb 335 SMART SM00849 97 307 1.9E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24835 057f82e3c4ed1ab728bbf819a8bec5fb 335 SUPERFAMILY SSF56281 35 327 9.04E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 SUPERFAMILY SSF49493 150 228 2.09E-17 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 Gene3D G3DSA:2.60.260.20 222 298 7.0E-20 T 06-07-2017 CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 Gene3D G3DSA:2.60.260.20 149 220 1.8E-14 T 06-07-2017 CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 PRINTS PR00625 DnaJ domain signature 40 60 1.2E-16 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 PRINTS PR00625 DnaJ domain signature 5 23 1.2E-16 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 PRINTS PR00625 DnaJ domain signature 23 38 1.2E-16 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 Pfam PF01556 DnaJ C terminal domain 156 297 2.3E-34 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 SUPERFAMILY SSF49493 224 303 2.62E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 SMART SM00271 2 60 2.6E-25 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 06-07-2017 IPR018253 DnaJ domain, conserved site CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 Gene3D G3DSA:1.10.287.110 2 87 1.8E-25 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 SUPERFAMILY SSF46565 1 99 4.71E-26 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS15865 d81de0b2294007f6a7e3126504add3a1 324 Pfam PF00226 DnaJ domain 3 65 4.0E-23 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 Gene3D G3DSA:3.10.20.80 9 85 3.0E-33 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 7 175 28.781 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 Gene3D G3DSA:3.30.110.10 86 174 1.1E-38 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 14 175 1.8E-67 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 90 174 1.3E-37 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 14 83 2.4E-28 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 ProSitePatterns PS00938 Initiation factor 3 signature. 65 78 - T 06-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 SUPERFAMILY SSF55200 91 174 3.53E-32 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09050 aada5d6bbdd6334e16b37d266336f2ca 175 SUPERFAMILY SSF54364 11 85 1.83E-27 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 SMART SM00418 12 94 4.2E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 Gene3D G3DSA:3.40.50.150 119 301 1.4E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 Pfam PF01022 Bacterial regulatory protein, arsR family 21 64 1.3E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 SUPERFAMILY SSF46785 8 137 2.04E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 44 1.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 1.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 SUPERFAMILY SSF53335 120 305 1.59E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 Gene3D G3DSA:1.10.10.10 7 86 2.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01850 fd8d368cec76f1778df19e77d858e79f 330 Pfam PF08241 Methyltransferase domain 159 255 5.0E-20 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 SUPERFAMILY SSF54631 202 337 8.17E-23 T 06-07-2017 CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 Gene3D G3DSA:3.10.580.10 200 342 5.4E-12 T 06-07-2017 CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 Pfam PF01595 Domain of unknown function DUF21 9 200 1.5E-45 T 06-07-2017 IPR002550 Domain of unknown function DUF21 CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 Pfam PF03471 Transporter associated domain 351 424 1.3E-18 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 Pfam PF00571 CBS domain 287 334 3.3E-6 T 06-07-2017 IPR000644 CBS domain CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 SUPERFAMILY SSF56176 347 430 3.0E-20 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 SMART SM01091 350 428 2.5E-26 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS08220 a18217f06994f03ea5b3be872b692cf3 433 Gene3D G3DSA:3.30.465.10 343 426 1.1E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS18990 52a6475c444062ab16560f5fa6c4e26a 188 Gene3D G3DSA:3.20.16.10 25 112 2.8E-5 T 06-07-2017 CAK95_RS18990 52a6475c444062ab16560f5fa6c4e26a 188 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 24 159 1.3E-31 T 06-07-2017 IPR006433 Prohead protease CAK95_RS18990 52a6475c444062ab16560f5fa6c4e26a 188 SUPERFAMILY SSF50789 25 144 1.18E-7 T 06-07-2017 CAK95_RS18990 52a6475c444062ab16560f5fa6c4e26a 188 Pfam PF04586 Caudovirus prohead serine protease 24 158 6.0E-38 T 06-07-2017 IPR006433 Prohead protease CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 Hamap MF_00367 GTPase Era [era]. 14 304 31.972 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 19 39 8.4E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 95 110 8.4E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 SUPERFAMILY SSF52540 19 213 6.79E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 SUPERFAMILY SSF54814 189 305 9.16E-41 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 Pfam PF07650 KH domain 218 292 1.4E-18 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 Pfam PF01926 50S ribosome-binding GTPase 19 133 3.4E-21 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 Gene3D G3DSA:3.40.50.300 5 177 4.8E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 172 6.1E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 Gene3D G3DSA:3.30.300.20 196 300 4.1E-39 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS22355 fc2255e641f6a18132b469ff0fd13413 311 TIGRFAM TIGR00436 era: GTP-binding protein Era 17 287 7.0E-74 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 240 6.2E-115 T 06-07-2017 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 Gene3D G3DSA:3.40.50.720 3 240 2.1E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 237 5.6E-63 T 06-07-2017 CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 178 3.7E-4 T 06-07-2017 CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 SUPERFAMILY SSF51735 3 240 1.79E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10350 97cd7cd1d919f040e4b4a2afd63ca510 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.2E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 Pfam PF12840 Helix-turn-helix domain 14 71 7.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 5.5E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 5.5E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 5.5E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 SUPERFAMILY SSF46785 10 104 8.93E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 SMART SM00418 13 87 3.2E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS26150 a8f7024b31bf6f35a22bfa38eab0e0bb 114 Gene3D G3DSA:1.10.10.10 8 112 7.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04205 6c48d11f9ef76572c62621cf2a15f328 152 Gene3D G3DSA:3.40.630.30 5 151 5.7E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04205 6c48d11f9ef76572c62621cf2a15f328 152 Pfam PF00583 Acetyltransferase (GNAT) family 65 130 2.6E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS04205 6c48d11f9ef76572c62621cf2a15f328 152 SUPERFAMILY SSF55729 5 150 7.26E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 Pfam PF00535 Glycosyl transferase family 2 6 113 4.5E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 Gene3D G3DSA:3.90.550.10 176 271 3.3E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 Gene3D G3DSA:3.90.550.10 5 140 3.3E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 SUPERFAMILY SSF53448 175 247 3.38E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 SUPERFAMILY SSF53448 4 125 3.38E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17620 239f16f8bc1913314a3f2047b4b0f204 282 Pfam PF02709 N-terminal domain of galactosyltransferase 174 237 5.5E-12 T 06-07-2017 IPR027791 Galactosyltransferase, C-terminal CAK95_RS14795 fa2ed87713c9c1b2acd62bb1801d976b 308 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 8 280 4.7E-112 T 06-07-2017 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CAK95_RS14795 fa2ed87713c9c1b2acd62bb1801d976b 308 PIRSF PIRSF028756 5 296 1.7E-81 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAK95_RS14795 fa2ed87713c9c1b2acd62bb1801d976b 308 Gene3D G3DSA:3.40.50.300 6 287 3.3E-95 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14795 fa2ed87713c9c1b2acd62bb1801d976b 308 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 33 265 3.2E-62 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAK95_RS14795 fa2ed87713c9c1b2acd62bb1801d976b 308 SUPERFAMILY SSF52540 119 252 1.46E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 SMART SM00448 3 116 4.4E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Gene3D G3DSA:3.40.50.2300 3 128 1.5E-35 T 06-07-2017 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 SMART SM00382 162 303 1.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 436 5.9E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 456 5.9E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Gene3D G3DSA:3.40.50.300 140 311 2.1E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Pfam PF00072 Response regulator receiver domain 5 113 2.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Gene3D G3DSA:1.10.10.60 406 455 4.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 SUPERFAMILY SSF46689 353 455 1.48E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Gene3D G3DSA:1.10.8.60 313 388 6.9E-23 T 06-07-2017 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Pfam PF00158 Sigma-54 interaction domain 142 306 3.6E-54 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 SUPERFAMILY SSF52540 142 374 8.38E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 SUPERFAMILY SSF52172 4 187 1.85E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS23265 c688d23bcf5b85b50d1e01613bd89905 456 Pfam PF02954 Bacterial regulatory protein, Fis family 413 452 1.8E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 Pfam PF01180 Dihydroorotate dehydrogenase 45 338 1.1E-88 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 291 311 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 SUPERFAMILY SSF51395 10 354 1.28E-98 T 06-07-2017 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 17 354 4.8E-107 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAK95_RS05665 e23b02be761fee23794e6972c632d70e 365 Gene3D G3DSA:3.20.20.70 5 354 1.8E-123 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS07700 cff6dec82bdaa1ec029577283f21a085 120 Gene3D G3DSA:3.40.390.10 85 111 3.6E-5 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK95_RS07700 cff6dec82bdaa1ec029577283f21a085 120 SUPERFAMILY SSF55486 2 116 4.02E-33 T 06-07-2017 CAK95_RS07700 cff6dec82bdaa1ec029577283f21a085 120 Pfam PF06262 Zinicin-like metallopeptidase 20 116 9.0E-35 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 SUPERFAMILY SSF51717 18 278 9.81E-88 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 24 275 3.4E-86 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 Pfam PF00809 Pterin binding enzyme 26 261 1.0E-74 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 25 40 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 Gene3D G3DSA:3.20.20.20 17 278 1.6E-97 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS18750 4b9ca452d551473820dda72fb7ceb2e6 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 59 72 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK95_RS25560 55f9070d9b0bebbf603572b28d6b2f3b 417 Gene3D G3DSA:3.40.630.30 189 340 5.2E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS25560 55f9070d9b0bebbf603572b28d6b2f3b 417 SUPERFAMILY SSF55729 193 359 1.92E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS25560 55f9070d9b0bebbf603572b28d6b2f3b 417 Pfam PF13480 Acetyltransferase (GNAT) domain 205 332 3.6E-16 T 06-07-2017 CAK95_RS06430 138d81c6361d8412b7ebba55f58f98b1 295 Gene3D G3DSA:3.40.50.720 3 223 1.1E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06430 138d81c6361d8412b7ebba55f58f98b1 295 Pfam PF13460 NAD(P)H-binding 8 199 8.8E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06430 138d81c6361d8412b7ebba55f58f98b1 295 SUPERFAMILY SSF51735 4 261 5.84E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 SUPERFAMILY SSF52210 123 292 6.41E-54 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 Pfam PF00549 CoA-ligase 151 274 6.7E-22 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 SMART SM00881 4 100 4.0E-36 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 PIRSF PIRSF001553 1 294 2.3E-130 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 SUPERFAMILY SSF51735 1 122 9.11E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 Gene3D G3DSA:3.40.50.261 120 291 4.9E-72 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.6E-40 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.6E-40 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.6E-40 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.6E-40 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 Pfam PF02629 CoA binding domain 6 99 7.0E-31 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 Gene3D G3DSA:3.40.50.720 2 119 9.0E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07480 f38168a3c40256c525a96509b4bd3ed4 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 292 1.8E-137 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 Pfam PF02107 Flagellar L-ring protein 69 251 9.0E-55 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 PRINTS PR01008 Flagellar L-ring protein signature 166 181 5.5E-26 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 PRINTS PR01008 Flagellar L-ring protein signature 229 243 5.5E-26 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 PRINTS PR01008 Flagellar L-ring protein signature 89 101 5.5E-26 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 PRINTS PR01008 Flagellar L-ring protein signature 192 208 5.5E-26 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 PRINTS PR01008 Flagellar L-ring protein signature 213 227 5.5E-26 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS18195 fcb9df13a0df145727924d12f2b74e0e 252 Hamap MF_00415 Flagellar L-ring protein [flgH]. 10 250 24.006 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAK95_RS24965 7a114012d886dd9404f60a700e51b97e 165 SUPERFAMILY SSF159894 2 103 1.96E-24 T 06-07-2017 CAK95_RS24965 7a114012d886dd9404f60a700e51b97e 165 Pfam PF04993 TfoX N-terminal domain 8 102 7.1E-27 T 06-07-2017 IPR007076 TfoX, N-terminal CAK95_RS24965 7a114012d886dd9404f60a700e51b97e 165 Gene3D G3DSA:3.30.1460.30 2 103 3.0E-28 T 06-07-2017 IPR007076 TfoX, N-terminal CAK95_RS23935 c601f1e501de8b590ecf95dbd0df4fd4 342 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 15 296 2.1E-48 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAK95_RS23935 c601f1e501de8b590ecf95dbd0df4fd4 342 SUPERFAMILY SSF51445 5 290 6.0E-68 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS23935 c601f1e501de8b590ecf95dbd0df4fd4 342 Gene3D G3DSA:3.20.20.300 6 291 6.4E-68 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 Pfam PF00672 HAMP domain 203 270 1.4E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 Gene3D G3DSA:1.10.287.950 371 575 2.2E-59 T 06-07-2017 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 SUPERFAMILY SSF158472 222 270 1.44E-9 T 06-07-2017 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 416 602 9.8E-55 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 SUPERFAMILY SSF58104 323 604 3.53E-70 T 06-07-2017 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 SMART SM00304 303 355 2.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 SMART SM00304 222 275 1.3E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS12570 e9ebef85326649ace77f59459c6677da 624 SMART SM00283 356 603 2.7E-94 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 SUPERFAMILY SSF54631 269 326 3.25E-10 T 06-07-2017 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 Pfam PF00571 CBS domain 210 264 1.4E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 Pfam PF00571 CBS domain 274 325 9.4E-10 T 06-07-2017 IPR000644 CBS domain CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 Pfam PF01380 SIS domain 52 181 4.9E-28 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 54 319 3.7E-91 T 06-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 SMART SM00116 218 266 0.34 T 06-07-2017 IPR000644 CBS domain CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 SMART SM00116 281 328 5.9E-4 T 06-07-2017 IPR000644 CBS domain CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 SUPERFAMILY SSF53697 33 269 4.23E-57 T 06-07-2017 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 Gene3D G3DSA:3.10.580.10 205 325 1.3E-33 T 06-07-2017 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 PIRSF PIRSF004692 1 329 3.6E-121 T 06-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CAK95_RS17650 5e5492d1fc06856357b5591d3ea697a8 329 Gene3D G3DSA:3.40.50.10490 42 200 2.7E-43 T 06-07-2017 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 80 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 SUPERFAMILY SSF53335 17 279 3.32E-80 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 Pfam PF00398 Ribosomal RNA adenine dimethylase 22 278 9.1E-48 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 Gene3D G3DSA:1.10.8.100 215 278 7.7E-20 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 279 53.823 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 SMART SM00650 36 212 8.3E-74 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 276 1.2E-70 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAK95_RS25860 4f91a5ad8b6b6d0dd77f4fe3b5958851 284 Gene3D G3DSA:3.40.50.150 7 212 2.8E-70 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS19585 0ba5786342666587b57883ad4bf0a73d 332 Gene3D G3DSA:3.30.450.90 26 118 9.2E-13 T 06-07-2017 CAK95_RS19585 0ba5786342666587b57883ad4bf0a73d 332 SUPERFAMILY SSF52540 28 287 6.45E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19585 0ba5786342666587b57883ad4bf0a73d 332 Gene3D G3DSA:3.40.50.300 123 289 1.3E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19585 0ba5786342666587b57883ad4bf0a73d 332 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 13 314 1.1E-131 T 06-07-2017 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 CAK95_RS19585 0ba5786342666587b57883ad4bf0a73d 332 Pfam PF00437 Type II/IV secretion system protein 27 290 4.9E-82 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAK95_RS03945 dde2bb0793d412c394e7aa6266675b5d 368 SUPERFAMILY SSF51556 62 363 1.7E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS03945 dde2bb0793d412c394e7aa6266675b5d 368 Pfam PF04909 Amidohydrolase 63 363 3.5E-28 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS03945 dde2bb0793d412c394e7aa6266675b5d 368 Gene3D G3DSA:3.20.20.140 62 363 1.3E-81 T 06-07-2017 CAK95_RS05060 5647b598eb2cd3440780b7693febc623 196 Gene3D G3DSA:3.40.50.1820 6 185 7.9E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS05060 5647b598eb2cd3440780b7693febc623 196 SUPERFAMILY SSF53474 28 183 1.96E-10 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS05060 5647b598eb2cd3440780b7693febc623 196 Pfam PF06821 Serine hydrolase 29 144 2.0E-6 T 06-07-2017 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CAK95_RS16060 665f4daea0b1cdc24dcfee7585463081 297 SUPERFAMILY SSF56281 4 297 1.01E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS16060 665f4daea0b1cdc24dcfee7585463081 297 Pfam PF12706 Beta-lactamase superfamily domain 50 264 1.9E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS16060 665f4daea0b1cdc24dcfee7585463081 297 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 297 132.386 T 06-07-2017 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 CAK95_RS16060 665f4daea0b1cdc24dcfee7585463081 297 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 4 297 1.4E-110 T 06-07-2017 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 CAK95_RS16060 665f4daea0b1cdc24dcfee7585463081 297 Gene3D G3DSA:3.60.15.10 4 297 2.2E-94 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 SUPERFAMILY SSF48008 104 251 7.32E-17 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 SUPERFAMILY SSF46785 33 121 1.73E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 SMART SM00895 108 246 5.2E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 Pfam PF07729 FCD domain 109 245 9.0E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 Gene3D G3DSA:1.20.120.530 101 255 1.1E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 Gene3D G3DSA:1.10.10.10 25 100 2.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 SMART SM00345 40 98 2.7E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS20960 bc101e6441433c5736d7c2e935bd3057 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 37 98 1.6E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 Pfam PF01047 MarR family 45 102 1.9E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 Gene3D G3DSA:1.10.10.10 9 153 6.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 SMART SM00347 38 138 4.3E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 SUPERFAMILY SSF46785 13 153 7.26E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 1.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 1.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 1.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS14740 ef296dda388137ed452eb4933dcb9ee3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 1.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS01815 fc284f857a8dfded2f6d921c4da90913 1216 Pfam PF01968 Hydantoinase/oxoprolinase 206 509 1.6E-117 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS01815 fc284f857a8dfded2f6d921c4da90913 1216 Pfam PF02538 Hydantoinase B/oxoprolinase 707 1213 8.9E-200 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS01815 fc284f857a8dfded2f6d921c4da90913 1216 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 8 187 5.2E-62 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS22660 4f98a1d13c45b206b7c3ad99d89bf975 159 ProSitePatterns PS00360 Ribosomal protein S9 signature. 98 116 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CAK95_RS22660 4f98a1d13c45b206b7c3ad99d89bf975 159 Pfam PF00380 Ribosomal protein S9/S16 39 159 3.8E-47 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22660 4f98a1d13c45b206b7c3ad99d89bf975 159 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 30 159 32.178 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid CAK95_RS22660 4f98a1d13c45b206b7c3ad99d89bf975 159 Gene3D G3DSA:3.30.230.10 33 159 1.4E-51 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS22660 4f98a1d13c45b206b7c3ad99d89bf975 159 SUPERFAMILY SSF54211 34 159 6.83E-48 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS10690 083fa0e8ea8768352da6dbdaf3e444f5 238 SMART SM00382 26 212 1.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10690 083fa0e8ea8768352da6dbdaf3e444f5 238 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS10690 083fa0e8ea8768352da6dbdaf3e444f5 238 SUPERFAMILY SSF52540 2 230 7.62E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10690 083fa0e8ea8768352da6dbdaf3e444f5 238 Gene3D G3DSA:3.40.50.300 1 227 1.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10690 083fa0e8ea8768352da6dbdaf3e444f5 238 Pfam PF00005 ABC transporter 18 161 2.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 SUPERFAMILY SSF51735 6 250 2.64E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 Gene3D G3DSA:3.40.50.720 2 251 8.9E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 250 4.2E-64 T 06-07-2017 CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.9E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08245 aef05192ae94076e7dd3f8b53828701d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 Pfam PF00034 Cytochrome c 75 171 9.6E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 PRINTS PR00604 Class IA and IB cytochrome C signature 145 155 1.1E-13 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 PRINTS PR00604 Class IA and IB cytochrome C signature 162 170 1.1E-13 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 PRINTS PR00604 Class IA and IB cytochrome C signature 126 142 1.1E-13 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 PRINTS PR00604 Class IA and IB cytochrome C signature 82 89 1.1E-13 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 PRINTS PR00604 Class IA and IB cytochrome C signature 95 110 1.1E-13 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 Gene3D G3DSA:1.10.760.10 70 174 4.4E-35 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS06735 c7c74c4ab2b1f8aaf3af23be5d0ca141 195 SUPERFAMILY SSF46626 70 174 5.96E-30 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 4 268 30.704 T 06-07-2017 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 Pfam PF01958 Domain of unknown function DUF108 169 256 2.3E-30 T 06-07-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 122 2.1E-13 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 Gene3D G3DSA:3.30.360.10 131 239 5.3E-32 T 06-07-2017 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 Gene3D G3DSA:3.40.50.720 1 130 2.6E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 SUPERFAMILY SSF51735 4 154 1.58E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 SUPERFAMILY SSF55347 125 238 5.89E-27 T 06-07-2017 CAK95_RS27325 386cae2271ba190e6e9caf420ef94f71 268 PIRSF PIRSF005227 2 268 4.3E-64 T 06-07-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 Gene3D G3DSA:3.65.10.10 26 211 2.1E-46 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 ProSitePatterns PS00104 EPSP synthase signature 1. 95 109 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 ProSitePatterns PS00885 EPSP synthase signature 2. 353 371 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 20 442 5.7E-123 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 16 443 31.716 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 PIRSF PIRSF000505 6 445 1.7E-127 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 16 435 4.8E-101 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 SUPERFAMILY SSF55205 16 443 3.76E-121 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAK95_RS10915 ee4841e4f64697efeee4aae14bd4e27a 446 Gene3D G3DSA:3.65.10.10 212 444 5.5E-55 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 SMART SM00332 1 237 1.3E-13 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 Pfam PF13672 Protein phosphatase 2C 16 196 1.6E-14 T 06-07-2017 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 SMART SM00331 24 239 1.0E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 SUPERFAMILY SSF81606 6 240 4.19E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 Pfam PF00069 Protein kinase domain 280 522 1.8E-37 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 Gene3D G3DSA:3.60.40.10 4 239 2.0E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 391 403 - T 06-07-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 Gene3D G3DSA:3.30.200.20 268 369 6.3E-13 T 06-07-2017 CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 SUPERFAMILY SSF56112 251 535 5.93E-59 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS12530 c1b1a7642938ba1d155284c3afb948a2 576 Gene3D G3DSA:1.10.510.10 370 526 8.9E-37 T 06-07-2017 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 148 6.5E-27 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 SUPERFAMILY SSF51735 4 182 4.0E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 166 323 3.1E-18 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 Gene3D G3DSA:3.30.360.10 165 320 1.5E-57 T 06-07-2017 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 SUPERFAMILY SSF55347 156 320 7.2E-54 T 06-07-2017 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 Gene3D G3DSA:3.40.50.720 3 164 1.4E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 6 352 3.6E-126 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 5 346 40.351 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS24825 edf64cf9cee91aef1b48127d6189ba94 352 SMART SM00859 6 148 4.5E-50 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK95_RS24335 4d41199afead5c7cba504248a6b5ffab 240 Gene3D G3DSA:3.90.75.10 72 124 1.3E-5 T 06-07-2017 CAK95_RS24335 4d41199afead5c7cba504248a6b5ffab 240 SUPERFAMILY SSF54060 53 173 1.88E-19 T 06-07-2017 CAK95_RS24335 4d41199afead5c7cba504248a6b5ffab 240 Gene3D G3DSA:1.10.10.60 149 178 3.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Pfam PF13426 PAS domain 171 278 8.0E-15 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Gene3D G3DSA:3.40.50.300 317 492 1.9E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SMART SM00382 340 484 4.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 125 1.3E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 164 286 4.1E-20 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 533 542 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 344 357 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 406 421 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SUPERFAMILY SSF55785 9 124 5.06E-12 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Gene3D G3DSA:1.10.10.60 546 627 1.1E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Gene3D G3DSA:1.10.8.60 493 545 9.1E-22 T 06-07-2017 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Gene3D G3DSA:3.30.450.20 159 277 1.5E-27 T 06-07-2017 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Gene3D G3DSA:3.30.450.20 9 124 1.6E-11 T 06-07-2017 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SMART SM00091 160 226 1.5E-8 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SMART SM00091 16 82 0.0057 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Pfam PF00158 Sigma-54 interaction domain 320 486 4.1E-69 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 Pfam PF13188 PAS domain 21 62 5.3E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SUPERFAMILY SSF52540 319 557 2.03E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28345 0dc57a64aee53cadef2083b899098e6c 640 SUPERFAMILY SSF55785 171 287 1.01E-25 T 06-07-2017 IPR000014 PAS domain CAK95_RS15235 e1b4682f1f93a794e3ad4e17f1f3cede 91 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 37 2.0E-4 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK95_RS15235 e1b4682f1f93a794e3ad4e17f1f3cede 91 SUPERFAMILY SSF47598 3 43 4.2E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK95_RS15235 e1b4682f1f93a794e3ad4e17f1f3cede 91 Gene3D G3DSA:1.10.1220.10 3 42 2.3E-5 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 206 216 1.1E-25 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 1.1E-25 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 17 33 1.1E-25 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 1.1E-25 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 341 5.0E-94 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 Pfam PF00579 tRNA synthetases class I (W and Y) 7 272 5.8E-74 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 Gene3D G3DSA:1.10.240.10 217 336 1.4E-16 T 06-07-2017 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 4 342 39.598 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 SUPERFAMILY SSF52374 7 341 1.09E-89 T 06-07-2017 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS09255 0e280d31245729d4999828e51bdc73e2 344 Gene3D G3DSA:3.40.50.620 6 216 1.3E-85 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS21645 6c6b3b6578575304faa256956acdf522 257 Pfam PF07486 Cell Wall Hydrolase 89 204 3.4E-10 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 CAK95_RS04300 ece116134edfa85b245e06e0f0d796ac 297 Hamap MF_01818 Ribonuclease BN [rbn]. 1 297 21.441 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CAK95_RS04300 ece116134edfa85b245e06e0f0d796ac 297 Pfam PF12706 Beta-lactamase superfamily domain 30 243 6.2E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04300 ece116134edfa85b245e06e0f0d796ac 297 Gene3D G3DSA:3.60.15.10 1 297 1.0E-59 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04300 ece116134edfa85b245e06e0f0d796ac 297 SMART SM00849 18 209 0.0041 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04300 ece116134edfa85b245e06e0f0d796ac 297 SUPERFAMILY SSF56281 1 297 1.24E-56 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Gene3D G3DSA:3.40.50.1000 541 689 3.1E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Gene3D G3DSA:3.40.50.1000 412 454 3.1E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 652 677 1.0E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 621 637 1.0E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF81653 244 337 1.1E-24 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 176 722 4.2E-154 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Gene3D G3DSA:3.30.70.100 22 101 1.7E-16 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 157 724 3.3E-158 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 288 302 1.9E-15 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 438 452 1.9E-15 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 640 1.9E-15 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 578 1.9E-15 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 656 1.9E-15 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Gene3D G3DSA:2.70.150.10 197 337 1.4E-26 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Pfam PF00403 Heavy-metal-associated domain 27 85 6.6E-10 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Pfam PF00122 E1-E2 ATPase 208 429 5.8E-59 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 704 2.6E-67 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 202 723 6.5E-102 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF56784 487 721 1.08E-39 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF56784 438 456 1.08E-39 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 Pfam PF00702 haloacid dehalogenase-like hydrolase 436 635 5.2E-31 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF55008 18 89 4.06E-16 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 440 446 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF81665 670 699 8.76E-12 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF81665 199 241 8.76E-12 T 06-07-2017 CAK95_RS16695 afd9884c976d1806a9868736300b8ff9 745 SUPERFAMILY SSF81665 339 432 8.76E-12 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Gene3D G3DSA:2.70.150.10 135 250 4.4E-41 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Gene3D G3DSA:2.70.150.10 46 80 4.4E-41 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SMART SM00831 29 102 9.4E-36 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Pfam PF00702 haloacid dehalogenase-like hydrolase 347 669 2.6E-25 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Pfam PF00689 Cation transporting ATPase, C-terminus 740 912 9.3E-38 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 655 671 9.4E-20 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 627 643 9.4E-20 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 687 712 9.4E-20 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 512 530 9.4E-20 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 108 371 2.5E-42 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 621 745 9.0E-36 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 350 364 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 691 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 674 2.6E-42 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF81653 139 249 2.48E-31 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF81665 250 344 7.59E-121 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF81665 28 140 7.59E-121 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF81665 705 915 7.59E-121 T 06-07-2017 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 352 358 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Pfam PF00122 E1-E2 ATPase 108 341 2.0E-67 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Pfam PF00690 Cation transporter/ATPase, N-terminus 30 97 4.1E-19 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF56784 509 758 3.05E-62 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF56784 348 368 3.05E-62 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Gene3D G3DSA:1.20.1110.10 624 914 4.7E-105 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Gene3D G3DSA:1.20.1110.10 81 134 4.7E-105 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 SUPERFAMILY SSF81660 357 558 9.16E-51 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS06500 377e300aad89846b20c7fbed9b68547f 934 Gene3D G3DSA:3.40.1110.10 340 561 1.2E-57 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS27120 8bcc34a06dc395a53ba852dfa2acf475 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 238 7.3E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27120 8bcc34a06dc395a53ba852dfa2acf475 260 SUPERFAMILY SSF161098 52 240 6.67E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27120 8bcc34a06dc395a53ba852dfa2acf475 260 Gene3D G3DSA:1.10.3720.10 51 242 8.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SMART SM00091 390 455 5.8E-6 T 06-07-2017 IPR000014 PAS domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SUPERFAMILY SSF158472 324 373 2.88E-9 T 06-07-2017 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Gene3D G3DSA:3.30.565.10 579 737 1.9E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Gene3D G3DSA:1.10.287.130 505 573 8.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 688 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 660 674 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 707 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Pfam PF00672 HAMP domain 305 372 4.8E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 619 729 4.3E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Pfam PF00512 His Kinase A (phospho-acceptor) domain 509 574 8.6E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SMART SM00304 323 376 1.6E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 396 503 1.1E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SUPERFAMILY SSF47384 502 575 1.22E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SUPERFAMILY SSF55874 579 733 2.62E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 PIRSF PIRSF037532 9 738 9.1E-251 T 06-07-2017 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SMART SM00387 617 734 3.0E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SMART SM00388 506 577 4.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Gene3D G3DSA:3.30.450.20 388 496 7.6E-17 T 06-07-2017 CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 SUPERFAMILY SSF55785 380 496 6.98E-11 T 06-07-2017 IPR000014 PAS domain CAK95_RS23260 02dec672c216aac97b5b634977f962ee 756 Pfam PF00989 PAS fold 393 495 1.4E-14 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:2.40.50.140 134 203 8.4E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF50249 137 204 3.58E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:3.30.300.20 284 351 3.7E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Pfam PF00575 S1 RNA binding domain 137 198 9.7E-7 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:3.30.1480.10 8 131 5.1E-47 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Pfam PF08529 NusA N-terminal domain 10 130 2.0E-35 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Pfam PF14520 Helix-hairpin-helix domain 438 473 0.0013 T 06-07-2017 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Pfam PF14520 Helix-hairpin-helix domain 371 417 3.6E-6 T 06-07-2017 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF54814 284 347 1.37E-16 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:1.10.150.20 437 508 2.4E-14 T 06-07-2017 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF69705 9 131 1.16E-39 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SMART SM00322 308 379 0.069 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SMART SM00322 235 307 0.56 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 10 347 9.5E-136 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF54814 205 282 1.18E-31 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 8 415 31.087 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF47794 435 507 2.98E-5 T 06-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SMART SM00316 139 205 7.1E-10 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:3.30.300.20 204 282 9.9E-38 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 370 419 1.8E-19 T 06-07-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Pfam PF13184 NusA-like KH domain 235 301 4.2E-29 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 Gene3D G3DSA:1.10.150.20 359 423 1.3E-19 T 06-07-2017 CAK95_RS09175 db58646ae090e840f26ede8d8b313c29 533 SUPERFAMILY SSF47794 358 419 1.51E-16 T 06-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 Gene3D G3DSA:3.40.50.1980 26 210 6.3E-30 T 06-07-2017 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 Gene3D G3DSA:3.40.50.1980 211 320 6.6E-18 T 06-07-2017 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00690 Adhesin family signature 36 54 7.1E-5 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00690 Adhesin family signature 210 231 7.1E-5 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00690 Adhesin family signature 67 80 7.1E-5 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00690 Adhesin family signature 263 281 7.1E-5 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 SUPERFAMILY SSF53807 32 319 1.42E-56 T 06-07-2017 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 318 1.1E-46 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00691 Adhesin B signature 36 57 4.0E-5 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00691 Adhesin B signature 61 79 4.0E-5 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13135 9adda32e76184cc2ca9b9527d902dd0c 324 PRINTS PR00691 Adhesin B signature 259 276 4.0E-5 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Pfam PF03129 Anticodon binding domain 381 490 1.6E-6 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 8 490 25.285 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 SUPERFAMILY SSF55681 10 365 4.21E-71 T 06-07-2017 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Gene3D G3DSA:3.40.50.800 379 491 5.3E-23 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Gene3D G3DSA:3.30.930.10 9 206 1.2E-79 T 06-07-2017 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Gene3D G3DSA:3.30.930.10 271 366 1.2E-79 T 06-07-2017 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 Pfam PF13393 Histidyl-tRNA synthetase 15 361 1.5E-43 T 06-07-2017 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 PIRSF PIRSF001549 6 498 1.1E-121 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 SUPERFAMILY SSF52954 380 457 1.8E-14 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS13260 ffeb8273e5ccd794457ad165ff8f3c78 502 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 12 457 1.1E-115 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 SUPERFAMILY SSF53822 33 382 1.71E-71 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 Pfam PF13458 Periplasmic binding protein 33 381 9.5E-67 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 75 93 7.9E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 350 365 7.9E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 34 50 7.9E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 56 72 7.9E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS06120 4c569dc4911f082fd57da18a3278b7da 418 Gene3D G3DSA:3.40.50.2300 32 234 2.8E-46 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 40 134 8.37E-26 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:3.30.2090.10 729 814 2.4E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:3.30.2090.10 200 277 1.6E-25 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 680 729 3.49E-28 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 816 865 3.49E-28 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:3.30.70.1320 139 199 1.1E-14 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82866 300 499 2.09E-50 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:1.20.1640.10 294 508 4.8E-61 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:1.10.3850.10 823 1034 1.3E-57 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:3.30.70.1430 40 138 1.4E-31 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 572 679 5.02E-23 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82714 730 814 1.83E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 137 184 6.1E-25 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82693 276 332 6.1E-25 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82866 840 1033 2.75E-44 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 SUPERFAMILY SSF82714 186 273 2.22E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Pfam PF00873 AcrB/AcrD/AcrF family 3 1035 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1053 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 Gene3D G3DSA:3.30.70.1430 575 679 1.2E-26 T 06-07-2017 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 628 642 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 559 576 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS17795 9136a9e8edae9b0da2fd7ac3be2805de 1057 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.4E-88 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 3.8E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 Gene3D G3DSA:3.40.50.300 3 244 1.3E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 SMART SM00382 30 224 1.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 Pfam PF00005 ABC transporter 21 177 2.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 SUPERFAMILY SSF52540 4 245 3.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25450 003d193fc17b00c19b20b9b1ede6afcd 248 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17925 aac90498cd54d3ec7b66cc2543530a78 274 Gene3D G3DSA:3.40.50.300 22 256 1.5E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17925 aac90498cd54d3ec7b66cc2543530a78 274 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17925 aac90498cd54d3ec7b66cc2543530a78 274 SUPERFAMILY SSF52540 26 254 1.59E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17925 aac90498cd54d3ec7b66cc2543530a78 274 Pfam PF00005 ABC transporter 42 192 1.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17925 aac90498cd54d3ec7b66cc2543530a78 274 SMART SM00382 51 240 1.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04400 48a5484a44793e33645552746017f001 99 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 10 55 12.879 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS04400 48a5484a44793e33645552746017f001 99 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 1 56 3.4E-21 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS04400 48a5484a44793e33645552746017f001 99 Pfam PF01165 Ribosomal protein S21 2 55 6.1E-20 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS04400 48a5484a44793e33645552746017f001 99 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 46 9.0E-12 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS04400 48a5484a44793e33645552746017f001 99 ProSitePatterns PS01181 Ribosomal protein S21 signature. 11 23 - T 06-07-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 538 564 0.017 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 268 5.5E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Pfam PF00005 ABC transporter 27 184 5.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Pfam PF00005 ABC transporter 333 487 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 SUPERFAMILY SSF52540 6 256 5.67E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 SUPERFAMILY SSF52540 327 558 8.68E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Gene3D G3DSA:3.40.50.300 5 258 3.4E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 SMART SM00382 341 544 2.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 SMART SM00382 35 234 5.3E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16960 ca2360cccbbee6221e53cc246b6b9748 567 Gene3D G3DSA:3.40.50.300 286 565 6.4E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25735 b73e54d2dc27548f4947ce1dfbb5e1c9 355 Pfam PF01594 Domain of unknown function DUF20 13 337 5.1E-63 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 Gene3D G3DSA:3.30.450.20 38 158 1.1E-12 T 06-07-2017 CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 SUPERFAMILY SSF58104 201 448 1.83E-56 T 06-07-2017 CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 SUPERFAMILY SSF55785 35 156 5.41E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 Pfam PF12860 PAS fold 50 162 7.3E-30 T 06-07-2017 CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 264 448 8.9E-32 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 SMART SM00283 195 449 2.2E-36 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 SMART SM00091 44 112 0.0051 T 06-07-2017 IPR000014 PAS domain CAK95_RS00500 47f6bddeadfddac7d9bcd8b0694630fb 454 Gene3D G3DSA:1.10.287.950 213 419 9.9E-46 T 06-07-2017 CAK95_RS04640 1f0d13da17028bab392fa9ce638670e5 156 Pfam PF04073 Aminoacyl-tRNA editing domain 23 141 2.6E-24 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS04640 1f0d13da17028bab392fa9ce638670e5 156 SUPERFAMILY SSF55826 7 147 1.57E-32 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS04640 1f0d13da17028bab392fa9ce638670e5 156 Gene3D G3DSA:3.90.960.10 7 146 4.4E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 694 2.9E-163 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 SUPERFAMILY SSF54665 4 156 7.2E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 180 287 1.1E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 134 1.3E-19 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 122 179 2.1E-43 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 289 364 2.1E-43 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 367 458 7.1E-64 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 610 758 7.1E-64 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 SUPERFAMILY SSF56003 126 760 1.07E-188 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.30.365.10 459 609 2.4E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 SMART SM01008 19 134 5.6E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS17800 4850a3ae02509351e08d5ac6a7df606b 768 Gene3D G3DSA:3.90.1170.50 5 121 4.6E-33 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Pfam PF09371 Tex-like protein N-terminal domain 15 197 6.6E-66 T 06-07-2017 IPR018974 Tex-like protein, N-terminal CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Pfam PF16921 Tex protein YqgF-like domain 328 453 1.8E-50 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SUPERFAMILY SSF47781 563 634 8.45E-20 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Pfam PF00575 S1 RNA binding domain 651 722 1.3E-18 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Pfam PF12836 Helix-hairpin-helix motif 493 557 7.7E-28 T 06-07-2017 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:1.10.10.650 8 115 3.9E-42 T 06-07-2017 IPR023319 Tex-like protein, HTH domain CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SMART SM00732 327 426 3.7E-35 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SMART SM00316 651 722 7.9E-25 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SUPERFAMILY SSF158832 8 322 6.15E-112 T 06-07-2017 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SUPERFAMILY SSF50249 639 727 5.45E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:3.30.420.140 327 452 3.4E-50 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:2.40.50.140 635 724 1.1E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:1.10.3500.10 453 500 6.9E-94 T 06-07-2017 IPR023323 Tex-like domain CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:1.10.3500.10 116 323 6.9E-94 T 06-07-2017 IPR023323 Tex-like domain CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 Gene3D G3DSA:1.10.150.310 501 632 4.0E-45 T 06-07-2017 IPR023097 Tex RuvX-like domain CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SUPERFAMILY SSF53098 323 471 7.21E-48 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS00740 b6fbd8389334fb5aa72470b3015fca7f 775 SUPERFAMILY SSF47781 472 560 4.45E-27 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS20965 bc7a73ec8177dcdd3f6ef79ed5c59919 299 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 87 296 1.5E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20965 bc7a73ec8177dcdd3f6ef79ed5c59919 299 SUPERFAMILY SSF56529 82 298 1.13E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20965 bc7a73ec8177dcdd3f6ef79ed5c59919 299 Gene3D G3DSA:3.90.850.10 79 298 5.3E-85 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS16505 5f56cea96f86b1797351b2df2470b53a 119 SUPERFAMILY SSF52172 2 118 9.25E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS16505 5f56cea96f86b1797351b2df2470b53a 119 Pfam PF00072 Response regulator receiver domain 4 113 3.7E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS16505 5f56cea96f86b1797351b2df2470b53a 119 SMART SM00448 2 113 1.8E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS16505 5f56cea96f86b1797351b2df2470b53a 119 Gene3D G3DSA:3.40.50.2300 3 118 2.1E-32 T 06-07-2017 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 302 8.1E-17 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 8.1E-17 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 181 8.1E-17 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 8.1E-17 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 SUPERFAMILY SSF51905 12 322 1.13E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 Gene3D G3DSA:3.50.50.60 255 334 5.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 Gene3D G3DSA:3.50.50.60 10 132 5.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 296 2.9E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 Hamap MF_01685 Ferredoxin--NADP reductase. 11 337 39.818 T 06-07-2017 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 Gene3D G3DSA:3.50.50.60 134 251 2.5E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 4.5E-11 T 06-07-2017 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 4.5E-11 T 06-07-2017 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 4.5E-11 T 06-07-2017 CAK95_RS17990 57a95b81c88ced62c0c3c88bec61ccd3 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 4.5E-11 T 06-07-2017 CAK95_RS12460 a75c0a589865e5a718f34a0548f21fea 109 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 86 1.0E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12460 a75c0a589865e5a718f34a0548f21fea 109 Gene3D G3DSA:3.10.20.30 9 95 5.1E-13 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS12460 a75c0a589865e5a718f34a0548f21fea 109 SUPERFAMILY SSF54292 5 94 4.58E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 Gene3D G3DSA:2.40.50.100 212 245 7.0E-14 T 06-07-2017 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 Gene3D G3DSA:2.40.50.100 49 81 7.0E-14 T 06-07-2017 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 SUPERFAMILY SSF111369 42 111 9.42E-9 T 06-07-2017 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 299 2.1E-14 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 SUPERFAMILY SSF111369 186 264 2.62E-6 T 06-07-2017 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 SUPERFAMILY SSF111369 120 177 2.22E-6 T 06-07-2017 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 328 343 3.1E-6 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS16790 c397ceea8e53aa91c70bb97a98d59dc6 356 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 59 79 3.1E-6 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 TIGRFAM TIGR01224 hutI: imidazolonepropionase 28 398 1.0E-137 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 Pfam PF01979 Amidohydrolase family 62 376 5.6E-13 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 399 39.676 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 Gene3D G3DSA:3.20.20.140 73 342 3.8E-37 T 06-07-2017 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 Gene3D G3DSA:2.30.40.10 27 72 4.6E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 SUPERFAMILY SSF51338 363 399 1.98E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 SUPERFAMILY SSF51338 3 64 1.98E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 Gene3D G3DSA:2.30.40.10 343 398 9.7E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS06095 8501efbdc519ebb423675ccbb1e8b399 399 SUPERFAMILY SSF51556 64 362 2.17E-80 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS25460 9ddbfdd818420b19937bae9301e29d1d 325 SUPERFAMILY SSF53850 111 287 4.43E-12 T 06-07-2017 CAK95_RS25460 9ddbfdd818420b19937bae9301e29d1d 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 1.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25460 9ddbfdd818420b19937bae9301e29d1d 325 PIRSF PIRSF017082 1 324 1.6E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20410 4a4f5bc5198fbbfd5116a37eeb0bdd0c 251 Pfam PF13478 XdhC Rossmann domain 77 218 1.1E-44 T 06-07-2017 IPR027051 XdhC Rossmann domain CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 Gene3D G3DSA:3.40.640.10 12 259 2.2E-75 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 14 390 1.7E-167 T 06-07-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 SUPERFAMILY SSF53383 45 389 3.34E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 388 7.5E-103 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 Gene3D G3DSA:3.90.1150.10 260 391 6.4E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS24220 24026e2b6a2a2d7268b1d943fd3eae7e 393 PIRSF PIRSF001434 1 392 1.3E-122 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS25750 8b85e2e72082cfb75f0fd061c467aa83 222 Pfam PF00551 Formyl transferase 4 185 7.4E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS25750 8b85e2e72082cfb75f0fd061c467aa83 222 SUPERFAMILY SSF53328 4 211 4.32E-62 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS25750 8b85e2e72082cfb75f0fd061c467aa83 222 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 4 195 2.7E-70 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAK95_RS25750 8b85e2e72082cfb75f0fd061c467aa83 222 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 5 191 31.097 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAK95_RS25750 8b85e2e72082cfb75f0fd061c467aa83 222 Gene3D G3DSA:3.40.50.170 3 197 1.1E-68 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 Gene3D G3DSA:3.40.50.300 19 137 2.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 Gene3D G3DSA:1.10.8.60 145 224 8.0E-11 T 06-07-2017 CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 Gene3D G3DSA:1.20.272.20 225 309 5.3E-4 T 06-07-2017 CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 SUPERFAMILY SSF48019 216 335 4.08E-11 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 Pfam PF06144 DNA polymerase III, delta subunit 24 190 2.3E-13 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 SUPERFAMILY SSF52540 18 210 8.14E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08160 13b6d1a2827d6fa9cf5f450c706fbcd0 342 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 335 7.0E-54 T 06-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 SUPERFAMILY SSF50249 36 136 8.39E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 Pfam PF00106 short chain dehydrogenase 171 362 7.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 132 1.3E-6 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 343 360 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 322 341 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 253 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 Gene3D G3DSA:3.40.50.720 172 385 5.7E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 SUPERFAMILY SSF51735 163 396 7.48E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27430 3cd4ab17b4f4502a5d11b727a4715f09 415 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 67 4.4E-10 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAK95_RS11135 8ad0c529c734daf2f37795efc14d0924 261 Gene3D G3DSA:3.40.50.150 32 245 2.3E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11135 8ad0c529c734daf2f37795efc14d0924 261 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 123 129 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK95_RS11135 8ad0c529c734daf2f37795efc14d0924 261 Pfam PF05175 Methyltransferase small domain 35 141 1.6E-12 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAK95_RS11135 8ad0c529c734daf2f37795efc14d0924 261 SUPERFAMILY SSF53335 4 176 1.13E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 Gene3D G3DSA:3.30.450.40 83 257 8.8E-44 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 SUPERFAMILY SSF46785 10 80 5.65E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 SMART SM00346 10 99 2.8E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 Pfam PF01614 Bacterial transcriptional regulator 130 251 3.1E-24 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 Gene3D G3DSA:1.10.10.10 8 80 8.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 SUPERFAMILY SSF55781 84 255 5.3E-37 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS15590 33c1b2bc0cf2b7abdc0916803758e34c 283 Pfam PF09339 IclR helix-turn-helix domain 12 62 1.1E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 SMART SM00926 69 123 1.3E-12 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 SUPERFAMILY SSF53706 68 627 7.2E-187 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Pfam PF01568 Molydopterin dinucleotide binding domain 856 983 4.3E-21 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 SUPERFAMILY SSF50692 851 988 7.23E-37 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 SUPERFAMILY SSF50692 787 817 7.23E-37 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:3.40.228.10 199 378 5.3E-62 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:2.40.40.20 661 685 1.7E-52 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:2.40.40.20 850 988 1.7E-52 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:2.40.40.20 803 814 1.7E-52 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:3.40.50.740 455 660 2.9E-33 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:3.40.50.740 379 406 2.9E-33 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 71 122 1.8E-10 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Gene3D G3DSA:2.20.25.90 69 123 7.7E-15 T 06-07-2017 CAK95_RS27830 f07a5db90f0466e84a80e31b4c82e4db 990 Pfam PF00384 Molybdopterin oxidoreductase 126 580 1.9E-54 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 313 6.8E-36 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 293 1.3E-99 T 06-07-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 Gene3D G3DSA:3.30.70.250 128 199 8.5E-25 T 06-07-2017 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 SUPERFAMILY SSF52151 193 311 1.54E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 SUPERFAMILY SSF52151 3 125 1.54E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 PIRSF PIRSF000446 1 312 6.5E-94 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 Pfam PF00698 Acyl transferase domain 5 278 8.1E-37 T 06-07-2017 IPR014043 Acyl transferase CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 SUPERFAMILY SSF55048 131 200 7.59E-16 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 Gene3D G3DSA:3.40.366.10 4 125 3.3E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK95_RS25900 b6af0255b6e7efea136ac2a5a4b0a16e 318 Gene3D G3DSA:3.40.366.10 200 304 3.3E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 Gene3D G3DSA:3.30.830.10 252 435 2.1E-34 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 SUPERFAMILY SSF63411 27 238 4.46E-39 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 Pfam PF00675 Insulinase (Peptidase family M16) 45 179 3.0E-5 T 06-07-2017 IPR011765 Peptidase M16, N-terminal CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 SUPERFAMILY SSF63411 255 436 1.2E-44 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 Pfam PF05193 Peptidase M16 inactive domain 195 368 1.4E-29 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAK95_RS13325 3d0c5ef8aeb6d0674b0ce5a5d018aca1 444 Gene3D G3DSA:3.30.830.10 29 240 3.8E-38 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS14125 5b0a974af65320d6a617f645edd1bd44 206 Pfam PF01464 Transglycosylase SLT domain 41 139 1.9E-16 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS14125 5b0a974af65320d6a617f645edd1bd44 206 SUPERFAMILY SSF53955 28 138 5.33E-27 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS14125 5b0a974af65320d6a617f645edd1bd44 206 Gene3D G3DSA:1.10.530.10 33 137 5.7E-25 T 06-07-2017 CAK95_RS04455 16fcfea6f36623b9590bd31541114f7c 251 Pfam PF00005 ABC transporter 22 176 5.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04455 16fcfea6f36623b9590bd31541114f7c 251 SUPERFAMILY SSF52540 4 246 3.85E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04455 16fcfea6f36623b9590bd31541114f7c 251 SMART SM00382 30 224 9.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04455 16fcfea6f36623b9590bd31541114f7c 251 Gene3D G3DSA:3.40.50.300 3 244 5.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25825 b93caaa90195a3bbe939c965361f7460 486 Gene3D G3DSA:3.40.50.1820 48 444 2.5E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25825 b93caaa90195a3bbe939c965361f7460 486 Pfam PF00450 Serine carboxypeptidase 82 443 5.1E-12 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 CAK95_RS25825 b93caaa90195a3bbe939c965361f7460 486 SUPERFAMILY SSF53474 72 469 2.77E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14045 adf68e374c087b3a8ea30f65ad399a61 529 SUPERFAMILY SSF55073 283 471 4.08E-56 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS14045 adf68e374c087b3a8ea30f65ad399a61 529 Gene3D G3DSA:3.30.70.1230 285 470 9.3E-48 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS14045 adf68e374c087b3a8ea30f65ad399a61 529 Pfam PF11845 Protein of unknown function (DUF3365) 24 202 9.1E-22 T 06-07-2017 IPR021796 Protein of unknown function DUF3365 CAK95_RS14045 adf68e374c087b3a8ea30f65ad399a61 529 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 287 468 4.4E-32 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS14045 adf68e374c087b3a8ea30f65ad399a61 529 SMART SM00044 257 452 8.7E-16 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 Pfam PF00175 Oxidoreductase NAD-binding domain 124 230 4.3E-20 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 Gene3D G3DSA:2.40.30.10 14 102 1.5E-23 T 06-07-2017 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 Pfam PF00970 Oxidoreductase FAD-binding domain 29 111 2.6E-13 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 Gene3D G3DSA:3.40.50.80 103 242 4.0E-37 T 06-07-2017 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 SUPERFAMILY SSF52343 103 246 6.42E-34 T 06-07-2017 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 SUPERFAMILY SSF63380 12 113 4.11E-24 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00406 Cytochrome B5 reductase signature 99 113 2.6E-10 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00406 Cytochrome B5 reductase signature 160 171 2.6E-10 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00406 Cytochrome B5 reductase signature 216 224 2.6E-10 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00406 Cytochrome B5 reductase signature 123 142 2.6E-10 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00406 Cytochrome B5 reductase signature 63 70 2.6E-10 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 157 1.1E-11 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 43 53 1.1E-11 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 63 70 1.1E-11 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 123 142 1.1E-11 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17250 f70408893832532d659730eaf37d7b9f 253 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 160 171 1.1E-11 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 10 292 9.1E-115 T 06-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 PIRSF PIRSF000006 1 292 2.1E-110 T 06-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 208 285 1.1E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 114 196 8.9E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Gene3D G3DSA:1.10.760.10 38 60 8.5E-27 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Gene3D G3DSA:1.10.760.10 103 200 8.5E-27 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 PRINTS PR00605 Class IC cytochrome C signature 263 285 3.9E-7 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 PRINTS PR00605 Class IC cytochrome C signature 122 133 3.9E-7 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 SUPERFAMILY SSF46626 205 291 2.12E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Gene3D G3DSA:1.10.760.10 209 292 1.4E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 SUPERFAMILY SSF46626 33 67 8.13E-29 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 SUPERFAMILY SSF46626 103 201 8.13E-29 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16710 095deb5b76429d34e5535779d1b814be 293 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 15 59 1.2E-25 T 06-07-2017 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 2.4E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 SUPERFAMILY SSF46785 1 75 5.22E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 Pfam PF03466 LysR substrate binding domain 83 288 3.6E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 SUPERFAMILY SSF53850 84 290 5.27E-47 T 06-07-2017 CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 Gene3D G3DSA:1.10.10.10 1 77 4.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 Gene3D G3DSA:3.40.190.10 86 168 4.1E-26 T 06-07-2017 CAK95_RS27680 112a9ed5bbb4d8c172b8ea91ab3bf3bb 297 Gene3D G3DSA:3.40.190.10 169 256 1.7E-17 T 06-07-2017 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 2.7E-42 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 SUPERFAMILY SSF54570 3 84 5.36E-34 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 PIRSF PIRSF002144 1 93 1.2E-33 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.674 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 Gene3D G3DSA:3.30.860.10 1 90 9.7E-41 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 Pfam PF00203 Ribosomal protein S19 3 83 2.7E-36 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.0E-21 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.0E-21 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21285 45f212a41953e73478baf80741c24978 95 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.0E-21 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.9E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 3.9E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 3.9E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 3.9E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Pfam PF00206 Lyase 12 342 2.6E-118 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Gene3D G3DSA:1.10.275.10 3 138 3.0E-62 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Gene3D G3DSA:1.10.40.30 405 463 1.1E-29 T 06-07-2017 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 5 460 7.2E-227 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Gene3D G3DSA:1.20.200.10 139 402 7.0E-104 T 06-07-2017 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 89.906 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 SUPERFAMILY SSF48557 4 462 1.54E-154 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK95_RS14565 59837c720d132e850561d01cda9a1a49 463 Pfam PF10415 Fumarase C C-terminus 408 461 1.0E-22 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 4.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 4.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 5.1E-86 T 06-07-2017 CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 PIRSF PIRSF000094 5 262 6.3E-113 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 SUPERFAMILY SSF51735 9 258 4.83E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15880 3a9138654ad1379a94ea553079b0def5 272 Gene3D G3DSA:3.40.50.720 10 204 3.4E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25270 f1bbb4523664aa5aa2c6e9dca59056a9 350 SUPERFAMILY SSF55961 105 338 1.21E-37 T 06-07-2017 CAK95_RS25270 f1bbb4523664aa5aa2c6e9dca59056a9 350 Gene3D G3DSA:2.102.10.10 6 119 1.6E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25270 f1bbb4523664aa5aa2c6e9dca59056a9 350 SUPERFAMILY SSF50022 1 119 8.9E-33 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25270 f1bbb4523664aa5aa2c6e9dca59056a9 350 Pfam PF00355 Rieske [2Fe-2S] domain 9 88 6.7E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 SUPERFAMILY SSF63380 1 97 1.28E-20 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 Pfam PF00677 Lumazine binding domain 104 188 9.7E-20 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 Pfam PF00677 Lumazine binding domain 3 90 2.6E-17 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 199 5.6E-50 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 SUPERFAMILY SSF63380 97 199 4.25E-31 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 PIRSF PIRSF000498 1 201 4.6E-67 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 Gene3D G3DSA:2.40.30.20 109 199 1.9E-28 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS22445 23f3985313610bd9a10fc045b36c8087 201 Gene3D G3DSA:2.40.30.20 5 108 5.0E-26 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK95_RS02400 40496d58aaea65abed92d932438da1fb 100 Pfam PF11604 Copper binding periplasmic protein CusF 32 97 9.0E-26 T 06-07-2017 IPR021647 Copper binding periplasmic protein CusF CAK95_RS14660 195a1aec366ab4e92337519d40108ada 280 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 59 227 1.5E-21 T 06-07-2017 IPR003734 Domain of unknown function DUF155 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 4.5E-31 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 Gene3D G3DSA:3.30.590.10 107 456 7.9E-134 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 SMART SM01230 103 379 1.9E-138 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 468 8.1E-200 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 SUPERFAMILY SSF54368 3 102 1.15E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 SUPERFAMILY SSF55931 104 468 1.86E-135 T 06-07-2017 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 Pfam PF00120 Glutamine synthetase, catalytic domain 104 466 2.1E-138 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 Gene3D G3DSA:3.10.20.70 3 106 6.5E-42 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS22675 260ad7a55a3f04845ed3e34a2510a823 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 26 153 1.0E-22 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 SUPERFAMILY SSF47090 185 247 1.84E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 SMART SM00644 16 153 2.8E-34 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 Pfam PF01471 Putative peptidoglycan binding domain 187 240 5.5E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 SUPERFAMILY SSF55846 11 169 5.1E-51 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 Gene3D G3DSA:3.40.80.10 11 171 3.6E-53 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK95_RS13560 e9b2d6dfa819f282effdd2b08f16f7cf 265 Gene3D G3DSA:1.10.101.10 176 247 8.7E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 SUPERFAMILY SSF53137 14 129 7.19E-50 T 06-07-2017 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 9.0E-59 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 Gene3D G3DSA:3.30.420.80 6 129 4.7E-57 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.082 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 Pfam PF00411 Ribosomal protein S11 19 128 3.4E-51 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 PIRSF PIRSF002131 1 129 1.0E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21380 87216ec2fc00f5f7bd0acf0c7abae657 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 Pfam PF02547 Queuosine biosynthesis protein 4 355 5.3E-124 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 355 1.5E-109 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 Gene3D G3DSA:3.40.1780.10 193 355 1.6E-92 T 06-07-2017 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 Gene3D G3DSA:3.40.1780.10 1 63 1.6E-92 T 06-07-2017 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 356 43.225 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 SUPERFAMILY SSF111337 1 355 3.92E-128 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAK95_RS22270 e4e9bd290d514cab07b20f51377d91ae 361 Gene3D G3DSA:2.40.10.240 65 149 1.4E-20 T 06-07-2017 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR01959 SuhB family inositol monophosphatase signature 158 184 2.5E-18 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR01959 SuhB family inositol monophosphatase signature 200 212 2.5E-18 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR01959 SuhB family inositol monophosphatase signature 19 41 2.5E-18 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR01959 SuhB family inositol monophosphatase signature 106 125 2.5E-18 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 SUPERFAMILY SSF56655 5 260 6.02E-84 T 06-07-2017 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 132 155 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 Gene3D G3DSA:3.40.190.80 154 261 2.1E-34 T 06-07-2017 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 Gene3D G3DSA:3.30.540.10 5 153 3.2E-51 T 06-07-2017 CAK95_RS04190 027156d5becc4c314edbe1ec88542333 266 Pfam PF00459 Inositol monophosphatase family 6 259 7.5E-62 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 PRINTS PR00127 Clp protease catalytic subunit P signature 108 125 4.1E-11 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 PRINTS PR00127 Clp protease catalytic subunit P signature 77 97 4.1E-11 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 PRINTS PR00127 Clp protease catalytic subunit P signature 184 203 4.1E-11 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 SUPERFAMILY SSF52096 40 206 1.16E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 Pfam PF00574 Clp protease 74 206 2.6E-28 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAK95_RS24465 ff72fe13f4b12820993b97096a9f9f4d 283 Gene3D G3DSA:3.90.226.10 41 206 3.8E-38 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06795 daf8b12cf63ae585643379da0e8068b6 187 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 187 25.953 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS06795 daf8b12cf63ae585643379da0e8068b6 187 SUPERFAMILY SSF53271 10 185 1.01E-35 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS06795 daf8b12cf63ae585643379da0e8068b6 187 Pfam PF00156 Phosphoribosyl transferase domain 47 164 4.3E-15 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS06795 daf8b12cf63ae585643379da0e8068b6 187 Gene3D G3DSA:3.40.50.2020 6 185 1.6E-49 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS06795 daf8b12cf63ae585643379da0e8068b6 187 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 20 183 1.1E-40 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 SUPERFAMILY SSF53383 5 378 2.96E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 376 3.7E-134 T 06-07-2017 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 Gene3D G3DSA:3.40.640.10 58 274 3.1E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 Gene3D G3DSA:3.90.1150.10 275 377 9.8E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS12835 d78bb776217fa1e8596b877e4898e971 385 Pfam PF00155 Aminotransferase class I and II 42 375 7.0E-55 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 SUPERFAMILY SSF56784 43 273 3.03E-39 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 41 273 9.1E-44 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 Gene3D G3DSA:3.40.50.1000 42 117 3.6E-37 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 Gene3D G3DSA:3.40.50.1000 194 275 3.6E-37 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 43 238 2.4E-18 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAK95_RS09785 b8071ee7e2ae981640f573f4bf7e4fba 281 Pfam PF02358 Trehalose-phosphatase 45 243 4.5E-33 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAK95_RS13925 8cb7e87f31444520a6e5bd8415ef40d2 285 Pfam PF03567 Sulfotransferase family 49 280 3.9E-22 T 06-07-2017 IPR005331 Sulfotransferase GO:0008146|GO:0016021 CAK95_RS13925 8cb7e87f31444520a6e5bd8415ef40d2 285 SUPERFAMILY SSF52540 55 279 1.49E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09825 32cf9ea1688fe301be78a70e50de4f16 216 Pfam PF00027 Cyclic nucleotide-binding domain 95 174 1.1E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS09825 32cf9ea1688fe301be78a70e50de4f16 216 Gene3D G3DSA:2.60.120.10 68 198 2.1E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS09825 32cf9ea1688fe301be78a70e50de4f16 216 SMART SM00100 82 187 1.2E-6 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS09825 32cf9ea1688fe301be78a70e50de4f16 216 SUPERFAMILY SSF51206 81 198 4.32E-22 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS17655 4c4ae0f3c9717081e1105787a280d5db 455 TIGRFAM TIGR04396 surf_polysacc: surface carbohydrate biosynthesis protein 6 327 6.8E-108 T 06-07-2017 IPR030906 Surface carbohydrate biosynthesis protein CAK95_RS17655 4c4ae0f3c9717081e1105787a280d5db 455 SUPERFAMILY SSF53756 207 368 2.95E-5 T 06-07-2017 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Gene3D G3DSA:1.10.286.20 203 244 1.5E-16 T 06-07-2017 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Gene3D G3DSA:1.10.8.10 2 55 1.3E-28 T 06-07-2017 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 303 7.7E-92 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Pfam PF00889 Elongation factor TS 71 287 1.7E-67 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 SUPERFAMILY SSF54713 148 305 1.57E-44 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 SUPERFAMILY SSF54713 56 143 1.7E-19 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 SUPERFAMILY SSF46934 4 55 1.09E-19 T 06-07-2017 IPR009060 UBA-like GO:0005515 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Gene3D G3DSA:3.30.479.20 150 196 5.4E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Gene3D G3DSA:3.30.479.20 245 286 5.4E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Gene3D G3DSA:3.30.479.20 57 149 3.3E-15 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS22960 51637e92698837c97922a14d78d40b1c 307 Hamap MF_00050 Elongation factor Ts [tsf]. 1 304 77.518 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS09110 906e2a9ec8e157677d98d0fda8033128 175 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 171 48.762 T 06-07-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS09110 906e2a9ec8e157677d98d0fda8033128 175 SUPERFAMILY SSF54637 4 168 6.99E-50 T 06-07-2017 IPR029069 HotDog domain CAK95_RS09110 906e2a9ec8e157677d98d0fda8033128 175 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 168 2.4E-85 T 06-07-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS09110 906e2a9ec8e157677d98d0fda8033128 175 Pfam PF07977 FabA-like domain 28 157 1.1E-48 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS09110 906e2a9ec8e157677d98d0fda8033128 175 Gene3D G3DSA:3.10.129.10 2 167 3.6E-55 T 06-07-2017 IPR029069 HotDog domain CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 SMART SM00419 192 240 5.2E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 Pfam PF13545 Crp-like helix-turn-helix domain 175 246 6.7E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 SMART SM00100 36 154 5.2E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 Gene3D G3DSA:2.60.120.10 31 168 1.6E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 Gene3D G3DSA:1.10.10.10 171 249 1.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 SUPERFAMILY SSF46785 171 248 1.17E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 SUPERFAMILY SSF51206 29 166 1.19E-26 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS17125 21df78653527eca6318429ee5bf0ee66 264 Pfam PF00027 Cyclic nucleotide-binding domain 55 142 5.0E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 Pfam PF00557 Metallopeptidase family M24 28 254 1.8E-50 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 262 1.7E-90 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 Hamap MF_01974 Methionine aminopeptidase [map]. 17 263 39.113 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 SUPERFAMILY SSF55920 22 267 1.7E-86 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 82 95 7.7E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 7.7E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 120 7.7E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 174 186 7.7E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 180 198 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK95_RS08260 b45910b04555ccad07f7c4a630090712 277 Gene3D G3DSA:3.90.230.10 19 266 4.3E-91 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 Gene3D G3DSA:2.30.22.10 134 191 4.7E-26 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 Hamap MF_01151 Protein GrpE [grpE]. 2 190 20.644 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 Gene3D G3DSA:3.90.20.20 44 133 6.5E-29 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 Pfam PF01025 GrpE 19 190 1.7E-52 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 SUPERFAMILY SSF58014 44 134 2.88E-25 T 06-07-2017 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 ProSitePatterns PS01071 grpE protein signature. 145 188 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 PRINTS PR00773 GrpE protein signature 169 188 9.7E-28 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 PRINTS PR00773 GrpE protein signature 142 157 9.7E-28 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 PRINTS PR00773 GrpE protein signature 54 70 9.7E-28 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 PRINTS PR00773 GrpE protein signature 82 97 9.7E-28 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK95_RS08900 1fd60713338a7a561e23067df494cf91 210 SUPERFAMILY SSF51064 136 191 2.35E-19 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 Pfam PF08359 YsiA-like protein, C-terminal region 104 199 1.4E-4 T 06-07-2017 IPR013570 Transcription regulator YsiA, C-terminal CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 Gene3D G3DSA:1.10.10.60 38 86 2.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 Gene3D G3DSA:1.10.357.10 87 228 3.0E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 SUPERFAMILY SSF48498 115 227 1.28E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 SUPERFAMILY SSF46689 38 120 7.77E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16030 1b20c90b2c889aa8a7d7422d557caa1f 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 88 1.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 Gene3D G3DSA:3.10.20.30 10 83 1.4E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 62 3.8E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 SUPERFAMILY SSF47741 94 164 6.67E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 SUPERFAMILY SSF54292 10 87 1.97E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 Pfam PF01799 [2Fe-2S] binding domain 82 155 1.3E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS25420 d3396cf9b5cc9b2e5f4c8935ac6ae27b 169 Gene3D G3DSA:1.10.150.120 84 165 1.3E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 Gene3D G3DSA:1.10.275.10 13 107 2.1E-33 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 SMART SM00998 368 447 3.1E-20 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 369 445 9.9E-15 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 Gene3D G3DSA:1.10.40.30 375 446 9.7E-23 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 3.8E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.8E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 3.8E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 3.8E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 Pfam PF00206 Lyase 19 297 4.9E-50 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 Gene3D G3DSA:1.20.200.10 108 374 4.7E-82 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 8.3E-7 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 8.3E-7 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 8.3E-7 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 8.3E-7 T 06-07-2017 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 11 353 2.1E-121 T 06-07-2017 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 SUPERFAMILY SSF48557 9 448 1.19E-103 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK95_RS20340 5b24a0d8cc2ba42a1bc290849cf1846a 454 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK95_RS24715 e77d14b17cffd1c2f430011eccfa12b9 574 Gene3D G3DSA:2.70.70.10 359 484 4.5E-9 T 06-07-2017 CAK95_RS24715 e77d14b17cffd1c2f430011eccfa12b9 574 Pfam PF01551 Peptidase family M23 387 468 2.9E-5 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS24715 e77d14b17cffd1c2f430011eccfa12b9 574 SUPERFAMILY SSF51261 360 484 2.09E-7 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 SUPERFAMILY SSF51621 10 268 1.14E-97 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 Gene3D G3DSA:3.20.20.60 7 268 1.1E-109 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 15 268 1.3E-90 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 263 3.8E-105 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 268 40.729 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK95_RS26050 5fcf944ef303598c352421db7f587cd3 275 PIRSF PIRSF000388 1 271 4.5E-106 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 Gene3D G3DSA:1.10.196.20 4 27 1.0E-7 T 06-07-2017 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 Pfam PF01642 Methylmalonyl-CoA mutase 60 522 4.1E-103 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 Gene3D G3DSA:3.20.20.240 37 474 4.1E-110 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 Gene3D G3DSA:3.40.50.280 479 606 1.1E-44 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 SUPERFAMILY SSF51703 5 516 1.46E-136 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18725 ea9a084d612afad359736b8a021cde60 607 SUPERFAMILY SSF52242 457 606 2.59E-36 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS15030 20cd1b2111c708da0c1c27088a5c8224 208 Gene3D G3DSA:3.40.50.150 35 125 3.4E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15030 20cd1b2111c708da0c1c27088a5c8224 208 SUPERFAMILY SSF53335 14 191 3.41E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17660 d2f55d18a8c0002eb14b85340a0f8ed5 392 SUPERFAMILY SSF53756 224 308 1.63E-7 T 06-07-2017 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 SUPERFAMILY SSF46689 24 91 4.36E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 Gene3D G3DSA:1.10.357.10 20 219 5.3E-53 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 165 217 2.6E-5 T 06-07-2017 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 SUPERFAMILY SSF48498 98 218 1.43E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 81 8.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00365 dd62dd3dfb0e133c435caccb78ae54d9 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 SUPERFAMILY SSF46689 20 87 3.49E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 SUPERFAMILY SSF48498 108 201 9.58E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 Pfam PF13977 Bacterial transcriptional repressor 110 196 1.3E-9 T 06-07-2017 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 Gene3D G3DSA:1.10.357.10 22 202 2.3E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 8.4E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS10035 d5509ee45d9d1125343acc56a98c5bb9 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS15795 7655f4552ff98e4a40a7a0d870a30769 290 Pfam PF07386 Protein of unknown function (DUF1499) 111 251 1.6E-29 T 06-07-2017 IPR010865 Protein of unknown function DUF1499 CAK95_RS02635 ac8997214ba40f06643117c3f60c4b49 709 Gene3D G3DSA:3.90.1530.10 13 123 1.3E-11 T 06-07-2017 CAK95_RS02635 ac8997214ba40f06643117c3f60c4b49 709 Pfam PF02195 ParB-like nuclease domain 16 117 3.7E-6 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS02635 ac8997214ba40f06643117c3f60c4b49 709 SMART SM00470 14 118 0.0013 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS02635 ac8997214ba40f06643117c3f60c4b49 709 SUPERFAMILY SSF110849 15 120 5.41E-12 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS02635 ac8997214ba40f06643117c3f60c4b49 709 SUPERFAMILY SSF109709 111 208 1.44E-20 T 06-07-2017 CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 Pfam PF02735 Ku70/Ku80 beta-barrel domain 15 179 2.2E-37 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 Gene3D G3DSA:2.40.290.10 5 175 5.5E-14 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 SUPERFAMILY SSF100939 4 258 1.8E-47 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 PIRSF PIRSF006493 1 299 1.2E-91 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 TIGRFAM TIGR02772 Ku_bact: Ku protein 4 259 9.7E-90 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 SMART SM00559 54 185 1.1E-22 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAK95_RS22225 4ce42cf50979face03edca6960ed30a7 303 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 3 258 30.841 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 SUPERFAMILY SSF55073 341 484 2.35E-31 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Gene3D G3DSA:3.30.450.20 49 163 2.8E-4 T 06-07-2017 CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Gene3D G3DSA:3.30.70.270 337 485 2.6E-34 T 06-07-2017 CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 SUPERFAMILY SSF55785 230 332 2.97E-9 T 06-07-2017 IPR000014 PAS domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 SMART SM00267 325 499 4.8E-37 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Pfam PF00990 Diguanylate cyclase, GGDEF domain 337 484 3.7E-32 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 SUPERFAMILY SSF55785 72 172 1.92E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Pfam PF13188 PAS domain 181 277 2.2E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Pfam PF13188 PAS domain 22 116 0.049 T 06-07-2017 IPR000014 PAS domain CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Gene3D G3DSA:3.30.450.20 232 323 5.8E-8 T 06-07-2017 CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 Gene3D G3DSA:3.30.450.20 164 197 5.8E-8 T 06-07-2017 CAK95_RS16265 b7e2db8e419e8d60687469f8d9389b95 506 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 332 483 4.0E-29 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 175 286 6.0E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 248 266 3.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 285 3.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 213 227 3.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 231 241 3.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SUPERFAMILY SSF52172 308 426 1.85E-33 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SUPERFAMILY SSF55874 115 285 9.95E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Gene3D G3DSA:3.30.565.10 113 285 5.4E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SUPERFAMILY SSF52172 432 535 3.27E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SMART SM00448 430 545 3.9E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SMART SM00448 310 420 1.7E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SMART SM00388 58 126 1.3E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Gene3D G3DSA:3.40.50.2300 308 428 2.9E-35 T 06-07-2017 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SMART SM00387 172 288 6.3E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Pfam PF00512 His Kinase A (phospho-acceptor) domain 59 126 8.2E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Gene3D G3DSA:1.10.287.130 51 112 1.7E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Pfam PF00072 Response regulator receiver domain 432 534 1.2E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Pfam PF00072 Response regulator receiver domain 312 420 4.3E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 SUPERFAMILY SSF47384 46 127 5.69E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04660 8b2b070f3b6fb2caeb8b660fe6b5517e 557 Gene3D G3DSA:3.40.50.2300 429 550 7.1E-27 T 06-07-2017 CAK95_RS11755 94c32c16a9549e112ccb10cf9143cc00 504 SUPERFAMILY SSF53649 5 439 1.45E-100 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS11755 94c32c16a9549e112ccb10cf9143cc00 504 Pfam PF00884 Sulfatase 5 344 4.3E-50 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS11755 94c32c16a9549e112ccb10cf9143cc00 504 Gene3D G3DSA:3.40.720.10 5 361 2.9E-79 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS11755 94c32c16a9549e112ccb10cf9143cc00 504 Gene3D G3DSA:3.30.1120.10 374 440 3.9E-13 T 06-07-2017 CAK95_RS05065 fa9ca55eba32ee48d6866c63c5b29aad 169 SMART SM00287 35 98 1.9E-5 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type CAK95_RS05065 fa9ca55eba32ee48d6866c63c5b29aad 169 SMART SM00287 101 164 0.49 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type CAK95_RS05065 fa9ca55eba32ee48d6866c63c5b29aad 169 Pfam PF06347 Bacterial SH3 domain 110 162 4.7E-14 T 06-07-2017 IPR010466 Protein of unknown function DUF1058 CAK95_RS05065 fa9ca55eba32ee48d6866c63c5b29aad 169 Pfam PF06347 Bacterial SH3 domain 41 97 1.8E-15 T 06-07-2017 IPR010466 Protein of unknown function DUF1058 CAK95_RS27250 c95e9ad45433cadf7a5ba966258d5c80 233 SUPERFAMILY SSF52540 2 224 2.72E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27250 c95e9ad45433cadf7a5ba966258d5c80 233 Pfam PF00005 ABC transporter 19 161 4.9E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27250 c95e9ad45433cadf7a5ba966258d5c80 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27250 c95e9ad45433cadf7a5ba966258d5c80 233 SMART SM00382 26 210 8.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27250 c95e9ad45433cadf7a5ba966258d5c80 233 Gene3D G3DSA:3.40.50.300 1 222 7.0E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 Hamap MF_00301 Homoserine kinase [thrB]. 1 325 167.856 T 06-07-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 Gene3D G3DSA:3.30.200.20 2 104 1.5E-38 T 06-07-2017 CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 Pfam PF01636 Phosphotransferase enzyme family 28 257 7.5E-35 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 Gene3D G3DSA:3.90.1200.10 106 312 8.2E-71 T 06-07-2017 CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 SUPERFAMILY SSF56112 5 310 3.95E-82 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS04270 f103452308cd64b7d4c906543b250fc5 325 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 2 307 4.6E-122 T 06-07-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAK95_RS17915 039e122996c2881e54cfe1b44a9f8bea 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 1.0E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17915 039e122996c2881e54cfe1b44a9f8bea 324 PIRSF PIRSF017082 1 323 1.0E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17915 039e122996c2881e54cfe1b44a9f8bea 324 SUPERFAMILY SSF53850 100 287 4.7E-8 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.30.70.20 137 203 9.6E-14 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:2.40.40.20 800 919 1.7E-38 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.40.50.740 560 786 1.3E-90 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.40.50.740 285 376 1.3E-90 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.10.20.30 11 68 1.5E-9 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 SUPERFAMILY SSF54292 11 133 4.11E-31 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:2.20.25.90 242 283 4.3E-22 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 SUPERFAMILY SSF53706 226 762 1.7E-201 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.40.228.10 377 559 1.7E-68 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Pfam PF01568 Molydopterin dinucleotide binding domain 809 915 9.1E-26 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Gene3D G3DSA:3.40.50.1780 204 241 1.6E-4 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Pfam PF00384 Molybdopterin oxidoreductase 285 724 3.9E-93 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 230 282 8.5E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 669 686 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 235 918 3.9E-227 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Pfam PF13187 4Fe-4S dicluster domain 153 211 1.9E-6 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 PIRSF PIRSF036643 6 928 0.0 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 10 87 1.3E-19 T 06-07-2017 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 SMART SM00926 229 282 3.6E-18 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 SUPERFAMILY SSF50692 775 919 2.87E-40 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS12785 df223fb9a68213dd77fcf7790000fe66 928 SUPERFAMILY SSF46548 116 215 6.28E-17 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 Gene3D G3DSA:1.10.520.20 9 113 6.6E-26 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 Hamap MF_01416 ATP synthase subunit delta [atpD]. 7 184 19.859 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 Pfam PF00213 ATP synthase delta (OSCP) subunit 11 182 1.8E-49 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 PRINTS PR00125 ATP synthase delta subunit signature 11 30 2.5E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 PRINTS PR00125 ATP synthase delta subunit signature 92 106 2.5E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 PRINTS PR00125 ATP synthase delta subunit signature 142 157 2.5E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 PRINTS PR00125 ATP synthase delta subunit signature 157 175 2.5E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 PRINTS PR00125 ATP synthase delta subunit signature 81 92 2.5E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 144 163 - T 06-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 SUPERFAMILY SSF47928 8 113 5.49E-25 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAK95_RS07390 fb5ed6fef5f2b442db5cb2a867218874 186 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 11 180 4.9E-37 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 SUPERFAMILY SSF48498 90 207 8.15E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 SUPERFAMILY SSF46689 14 89 1.95E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 Gene3D G3DSA:1.10.357.10 69 208 6.3E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 Gene3D G3DSA:1.10.10.60 15 68 4.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12090 3e6ff96f5597d757e3744e42d0357de7 212 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 168 206 1.0E-5 T 06-07-2017 CAK95_RS24480 c247bc709624c2d6cfb31bed40684123 190 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 41 147 2.2E-21 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS24480 c247bc709624c2d6cfb31bed40684123 190 Pfam PF05119 Phage terminase, small subunit 52 147 4.6E-22 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS25890 3d944447732915387870345dd6dba796 79 Gene3D G3DSA:1.10.1200.10 3 76 3.0E-33 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS25890 3d944447732915387870345dd6dba796 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 3.1E-33 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25890 3d944447732915387870345dd6dba796 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK95_RS25890 3d944447732915387870345dd6dba796 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 1.0E-13 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25890 3d944447732915387870345dd6dba796 79 Pfam PF00550 Phosphopantetheine attachment site 6 72 6.6E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS25890 3d944447732915387870345dd6dba796 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.279 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25890 3d944447732915387870345dd6dba796 79 SUPERFAMILY SSF47336 2 76 2.09E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 PRINTS PR00061 Ribosomal protein L19 signature 92 117 6.9E-35 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 PRINTS PR00061 Ribosomal protein L19 signature 8 37 6.9E-35 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 PRINTS PR00061 Ribosomal protein L19 signature 38 67 6.9E-35 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 SUPERFAMILY SSF50104 1 119 9.33E-46 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.772 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 3.4E-47 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 PIRSF PIRSF002191 1 132 1.5E-54 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS07665 eee386a8cb1e1b90d4472d53103c612a 133 Pfam PF01245 Ribosomal protein L19 2 116 5.3E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09290 97f962a10c602d725777cab63acd3f96 437 SUPERFAMILY SSF55961 139 391 1.06E-44 T 06-07-2017 CAK95_RS09290 97f962a10c602d725777cab63acd3f96 437 SUPERFAMILY SSF50022 21 137 9.3E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS09290 97f962a10c602d725777cab63acd3f96 437 Gene3D G3DSA:2.102.10.10 24 141 3.4E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS09290 97f962a10c602d725777cab63acd3f96 437 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 69 91 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAK95_RS09290 97f962a10c602d725777cab63acd3f96 437 Pfam PF00355 Rieske [2Fe-2S] domain 27 109 4.2E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Pfam PF02151 UvrB/uvrC motif 248 276 3.0E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SUPERFAMILY SSF46600 228 281 2.22E-10 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SUPERFAMILY SSF47781 581 669 5.72E-22 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Gene3D G3DSA:4.10.860.10 220 281 6.7E-15 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 47 494 4.7E-133 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 420 602 1.6E-52 T 06-07-2017 IPR001162 UvrC family homology region CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Hamap MF_00203 UvrABC system protein C [uvrC]. 42 667 28.105 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Gene3D G3DSA:3.40.1440.10 56 136 4.2E-7 T 06-07-2017 IPR027299 GIY-YIG domain CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SUPERFAMILY SSF82771 55 138 2.62E-20 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Pfam PF14520 Helix-hairpin-helix domain 618 665 2.3E-11 T 06-07-2017 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SMART SM00465 55 136 9.7E-16 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Pfam PF01541 GIY-YIG catalytic domain 57 129 6.6E-9 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 Gene3D G3DSA:1.10.150.20 618 669 4.9E-23 T 06-07-2017 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SMART SM00278 616 635 33.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK95_RS01630 dd4c86dfa3bd645d4075608f53033b30 673 SMART SM00278 648 667 3.6 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK95_RS06180 7ebfb8e7150bc1ad67f76adcb4ad5937 152 Pfam PF11578 Protein of unknown function (DUF3237) 6 151 7.5E-42 T 06-07-2017 IPR020915 Uncharacterised protein family UPF0311 CAK95_RS06180 7ebfb8e7150bc1ad67f76adcb4ad5937 152 Gene3D G3DSA:2.40.160.20 2 151 3.1E-50 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Gene3D G3DSA:3.90.190.20 318 452 6.0E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Gene3D G3DSA:3.40.50.720 7 89 5.3E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Pfam PF08245 Mur ligase middle domain 119 297 2.9E-29 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 SUPERFAMILY SSF53623 110 314 5.76E-51 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 455 31.75 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 SUPERFAMILY SSF51984 6 97 2.82E-11 T 06-07-2017 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Gene3D G3DSA:3.40.1190.10 98 316 7.0E-61 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 SUPERFAMILY SSF53244 316 455 1.24E-36 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 453 2.8E-109 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 117 140 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAK95_RS14505 b91de107374c72703b3698cb055b5282 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 360 2.9E-6 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS21805 203acf7a56cbf7b600bd685a7c95e3b0 216 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 81 1.6E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS21805 203acf7a56cbf7b600bd685a7c95e3b0 216 SUPERFAMILY SSF52833 4 87 5.28E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21805 203acf7a56cbf7b600bd685a7c95e3b0 216 Gene3D G3DSA:1.20.1050.10 93 207 1.3E-39 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS21805 203acf7a56cbf7b600bd685a7c95e3b0 216 Gene3D G3DSA:3.40.30.10 11 92 1.5E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21805 203acf7a56cbf7b600bd685a7c95e3b0 216 SUPERFAMILY SSF47616 81 209 6.66E-15 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 SUPERFAMILY SSF56091 7 203 1.15E-34 T 06-07-2017 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 321 5.2E-16 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Gene3D G3DSA:3.30.1490.70 162 203 2.6E-11 T 06-07-2017 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Gene3D G3DSA:3.30.1490.70 4 33 2.6E-11 T 06-07-2017 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Gene3D G3DSA:3.30.470.30 34 146 2.7E-22 T 06-07-2017 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Pfam PF01068 ATP dependent DNA ligase domain 23 203 1.7E-25 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 SUPERFAMILY SSF50249 206 327 7.71E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS11000 fab97c454ff75160815e0d154e30387b 343 Gene3D G3DSA:2.40.50.140 206 327 1.5E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.2E-10 T 06-07-2017 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 1.2E-10 T 06-07-2017 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 SUPERFAMILY SSF46977 435 578 1.1E-36 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 SUPERFAMILY SSF51905 10 265 2.6E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 SUPERFAMILY SSF51905 361 417 2.6E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.7E-5 T 06-07-2017 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 1.7E-5 T 06-07-2017 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Pfam PF02910 Fumarate reductase flavoprotein C-term 448 563 2.3E-12 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Gene3D G3DSA:1.20.58.100 418 528 1.7E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 PIRSF PIRSF000171 4 567 8.7E-221 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Pfam PF00890 FAD binding domain 14 386 2.6E-35 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Gene3D G3DSA:4.10.80.40 529 555 6.4E-5 T 06-07-2017 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Gene3D G3DSA:3.50.50.60 11 282 5.5E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03740 9079d29b846cf3f488fbe31e00bf720b 582 Gene3D G3DSA:3.50.50.60 361 417 5.5E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 SUPERFAMILY SSF51905 284 364 2.07E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 SUPERFAMILY SSF51905 1 173 2.07E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 Pfam PF01494 FAD binding domain 271 326 7.0E-5 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 Gene3D G3DSA:3.50.50.60 275 355 5.6E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 Gene3D G3DSA:3.50.50.60 1 178 5.6E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 6.0E-12 T 06-07-2017 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 6.0E-12 T 06-07-2017 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 6.0E-12 T 06-07-2017 CAK95_RS16650 972ecb3d5ade3fd6865ca76a7dd29d18 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 6.0E-12 T 06-07-2017 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 SUPERFAMILY SSF54909 62 142 1.88E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 SUPERFAMILY SSF46785 2 91 3.81E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 Gene3D G3DSA:3.30.70.920 54 136 2.2E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 1.9E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 SMART SM00344 1 110 5.8E-38 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 3.2E-18 T 06-07-2017 CAK95_RS05180 39a22df61c9753ae7950d3c37bb8a5d8 155 Gene3D G3DSA:1.10.10.10 2 53 6.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 SUPERFAMILY SSF46785 14 123 4.79E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 8.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 8.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 8.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 Pfam PF03466 LysR substrate binding domain 101 311 7.0E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 SUPERFAMILY SSF53850 101 314 3.71E-30 T 06-07-2017 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 Gene3D G3DSA:3.40.190.10 198 248 1.8E-11 T 06-07-2017 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 Gene3D G3DSA:1.10.10.10 16 101 5.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 76 2.1E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12535 cdf4ea5b607e2eb88636500dd920a233 330 Gene3D G3DSA:3.40.190.10 102 197 1.5E-15 T 06-07-2017 CAK95_RS04945 e17ebb90d347b22831d7cddbc22d607d 415 SUPERFAMILY SSF53850 164 391 1.07E-7 T 06-07-2017 CAK95_RS04945 e17ebb90d347b22831d7cddbc22d607d 415 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 136 411 1.2E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10175 73dcade3152ca947d03147ed0bbc4887 264 Gene3D G3DSA:3.40.50.300 3 220 4.1E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10175 73dcade3152ca947d03147ed0bbc4887 264 SUPERFAMILY SSF52540 8 228 8.57E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10175 73dcade3152ca947d03147ed0bbc4887 264 Pfam PF00005 ABC transporter 27 166 4.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10175 73dcade3152ca947d03147ed0bbc4887 264 SMART SM00382 36 229 8.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02365 db91b4ff08a558c755043b8d5475f9a4 138 Pfam PF01292 Prokaryotic cytochrome b561 22 130 1.4E-7 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAK95_RS02365 db91b4ff08a558c755043b8d5475f9a4 138 SUPERFAMILY SSF81342 18 132 8.63E-16 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Pfam PF02769 AIR synthase related protein, C-terminal domain 568 704 3.2E-20 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Pfam PF02769 AIR synthase related protein, C-terminal domain 201 350 6.4E-34 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 SUPERFAMILY SSF55326 13 193 1.94E-49 T 06-07-2017 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 737 333.042 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 SUPERFAMILY SSF55326 396 560 6.98E-56 T 06-07-2017 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 PIRSF PIRSF001587 2 733 1.9E-284 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 17 730 2.6E-285 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 SUPERFAMILY SSF56042 564 721 1.24E-36 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Pfam PF00586 AIR synthase related protein, N-terminal domain 437 553 4.9E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Pfam PF00586 AIR synthase related protein, N-terminal domain 86 187 3.6E-23 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 SUPERFAMILY SSF56042 200 422 1.23E-57 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Gene3D G3DSA:3.30.1330.10 49 191 3.4E-48 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS26505 4f296e70e213a477174f1cfc4d164274 737 Gene3D G3DSA:3.30.1330.10 411 557 7.0E-57 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 Pfam PF00263 Bacterial type II and III secretion system protein 270 438 1.6E-41 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 Pfam PF04972 BON domain 120 169 4.0E-8 T 06-07-2017 IPR007055 BON domain CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 Pfam PF13629 Pilus formation protein N terminal region 46 115 1.2E-18 T 06-07-2017 IPR032789 Pilus formation protein, N-terminal CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 PRINTS PR00811 Bacterial general secretion pathway protein D signature 402 420 2.3E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 PRINTS PR00811 Bacterial general secretion pathway protein D signature 266 290 2.3E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 PRINTS PR00811 Bacterial general secretion pathway protein D signature 193 203 2.3E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAK95_RS06655 004abd5272b1a2e24f6371f2fbb71af3 491 PRINTS PR00811 Bacterial general secretion pathway protein D signature 425 439 2.3E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 Gene3D G3DSA:3.90.180.10 1 149 1.9E-36 T 06-07-2017 IPR011032 GroES-like CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 Gene3D G3DSA:3.40.50.720 150 233 5.9E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 SMART SM00829 10 304 1.0E-20 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 SUPERFAMILY SSF51735 117 249 1.2E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 SUPERFAMILY SSF50129 1 142 7.15E-29 T 06-07-2017 IPR011032 GroES-like CAK95_RS27420 58b35233a0e05659a3febfe5420db2a8 315 Pfam PF13602 Zinc-binding dehydrogenase 187 303 1.2E-18 T 06-07-2017 CAK95_RS05310 9fc9127caf5d42b16e0a99c92354d027 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 4.3E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05310 9fc9127caf5d42b16e0a99c92354d027 327 SUPERFAMILY SSF53850 125 285 1.27E-6 T 06-07-2017 CAK95_RS05310 9fc9127caf5d42b16e0a99c92354d027 327 PIRSF PIRSF017082 1 327 1.4E-62 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 SUPERFAMILY SSF50129 325 375 3.91E-12 T 06-07-2017 IPR011032 GroES-like CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 Pfam PF00107 Zinc-binding dehydrogenase 197 326 6.8E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 Gene3D G3DSA:3.40.50.720 191 315 1.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 SUPERFAMILY SSF51735 160 340 4.44E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 SUPERFAMILY SSF50129 1 186 7.91E-68 T 06-07-2017 IPR011032 GroES-like CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3 375 1.7E-178 T 06-07-2017 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|Reactome: R-HSA-71384 CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 Gene3D G3DSA:3.90.180.10 2 190 4.7E-60 T 06-07-2017 IPR011032 GroES-like CAK95_RS21660 520a24b90fa8e55a40cf2aef00cff54c 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 112 1.9E-23 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 Gene3D G3DSA:3.90.226.10 274 496 6.8E-8 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 15 562 4.0E-286 T 06-07-2017 IPR017633 Benzoyl-CoA-dihydrodiol lyase MetaCyc: PWY-1361 CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 SUPERFAMILY SSF52096 23 244 5.89E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 Gene3D G3DSA:3.90.226.10 17 244 1.3E-35 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 Pfam PF00378 Enoyl-CoA hydratase/isomerase 56 244 6.4E-18 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS09730 8e65e01926fad9af6b7bcfa745a6ce40 562 SUPERFAMILY SSF52096 275 551 4.77E-15 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06515 140eceb8c54a3618ee6b99d95228e7ca 123 Pfam PF04248 Domain of unknown function (DUF427) 19 110 2.7E-34 T 06-07-2017 IPR007361 Domain of unknown function DUF427 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Gene3D G3DSA:2.40.50.140 1 114 1.2E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 SUPERFAMILY SSF50104 126 271 5.96E-61 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 7.2E-33 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.5E-56 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 SMART SM01382 124 252 2.4E-90 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.089 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 9.6E-126 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Gene3D G3DSA:4.10.950.10 196 273 1.3E-32 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 SUPERFAMILY SSF50249 2 125 3.77E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 PIRSF PIRSF002158 3 275 1.3E-98 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 Gene3D G3DSA:2.30.30.30 118 195 4.0E-34 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK95_RS21280 89f0b5bf6f82e770372c9a9bff7634bc 279 SMART SM01383 42 118 2.0E-44 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS12240 7568d9830783bc473b7ce68f77a466b0 255 Gene3D G3DSA:3.40.50.300 3 251 8.2E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12240 7568d9830783bc473b7ce68f77a466b0 255 Pfam PF00005 ABC transporter 20 182 4.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12240 7568d9830783bc473b7ce68f77a466b0 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 253 7.4E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS12240 7568d9830783bc473b7ce68f77a466b0 255 SUPERFAMILY SSF52540 4 252 4.71E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12240 7568d9830783bc473b7ce68f77a466b0 255 SMART SM00382 29 230 1.0E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26820 5402d1cee1d5f561af75b23ebd2a9db6 275 Gene3D G3DSA:3.40.50.150 73 251 2.6E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26820 5402d1cee1d5f561af75b23ebd2a9db6 275 SUPERFAMILY SSF53335 146 257 1.95E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26820 5402d1cee1d5f561af75b23ebd2a9db6 275 SUPERFAMILY SSF53335 47 110 1.95E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 PIRSF PIRSF000094 2 259 2.7E-106 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 Gene3D G3DSA:3.40.50.720 7 200 3.3E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 SUPERFAMILY SSF51735 6 253 3.49E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09125 5b5787902c77df50b18e0994ee6457f3 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 1.6E-82 T 06-07-2017 CAK95_RS23590 503560b029b434b903b3e6cf636bb943 348 SUPERFAMILY SSF55073 160 341 2.98E-55 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS23590 503560b029b434b903b3e6cf636bb943 348 SMART SM00044 136 325 1.6E-47 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS23590 503560b029b434b903b3e6cf636bb943 348 Gene3D G3DSA:3.30.70.1230 161 343 9.3E-59 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS23590 503560b029b434b903b3e6cf636bb943 348 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 168 343 1.9E-49 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS00040 623a85cc681accf9bb0c9a5665a45d0f 155 SUPERFAMILY SSF55961 4 148 9.34E-27 T 06-07-2017 CAK95_RS00040 623a85cc681accf9bb0c9a5665a45d0f 155 Gene3D G3DSA:3.30.530.20 8 150 7.3E-31 T 06-07-2017 IPR023393 START-like domain CAK95_RS00040 623a85cc681accf9bb0c9a5665a45d0f 155 Pfam PF08982 Domain of unknown function (DUF1857) 8 149 1.2E-31 T 06-07-2017 IPR015075 Protein of unknown function DUF1857 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 273 291 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 1.3E-75 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 Gene3D G3DSA:3.50.50.60 4 122 1.0E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 Gene3D G3DSA:3.50.50.60 230 306 5.7E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 SUPERFAMILY SSF51905 1 309 1.17E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 310 1.5E-123 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.5E-38 T 06-07-2017 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.5E-38 T 06-07-2017 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.5E-38 T 06-07-2017 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.5E-38 T 06-07-2017 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 1.5E-38 T 06-07-2017 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 299 6.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13755 a50eb545cf78b5b29e5aaf6d5cf6e40d 321 Gene3D G3DSA:3.50.50.60 123 229 4.0E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 38 101 1.5E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 PIRSF PIRSF000005 3 197 2.7E-38 T 06-07-2017 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 SUPERFAMILY SSF46626 114 196 1.72E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 SUPERFAMILY SSF46626 38 105 2.9E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Gene3D G3DSA:1.10.760.10 140 196 2.2E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Gene3D G3DSA:1.10.760.10 44 105 6.7E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Pfam PF00034 Cytochrome c 119 193 1.2E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Gene3D G3DSA:1.10.3820.10 7 43 1.1E-5 T 06-07-2017 CAK95_RS16085 cb5406b7df3b4c8221adc32b82ca28a8 197 Gene3D G3DSA:1.10.3820.10 112 139 1.1E-5 T 06-07-2017 CAK95_RS05200 24db1f78a11566f026675565548a6886 259 Gene3D G3DSA:3.40.50.720 5 254 8.7E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05200 24db1f78a11566f026675565548a6886 259 SUPERFAMILY SSF51735 7 254 2.05E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05200 24db1f78a11566f026675565548a6886 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 7.3E-36 T 06-07-2017 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 46 110 4.5E-15 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 PRINTS PR01183 Ribonucleotide reductase large chain signature 186 205 1.1E-14 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 PRINTS PR01183 Ribonucleotide reductase large chain signature 439 466 1.1E-14 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 398 1.1E-14 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 SUPERFAMILY SSF48168 38 109 3.14E-17 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 SUPERFAMILY SSF51998 520 591 5.8E-136 T 06-07-2017 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 SUPERFAMILY SSF51998 112 489 5.8E-136 T 06-07-2017 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 Pfam PF02867 Ribonucleotide reductase, barrel domain 441 586 1.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 Pfam PF02867 Ribonucleotide reductase, barrel domain 114 432 2.5E-73 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 Gene3D G3DSA:3.20.70.20 546 584 9.8E-55 T 06-07-2017 CAK95_RS07785 9b8f942a369413d336d015ddaa42a981 626 Gene3D G3DSA:3.20.70.20 40 485 9.8E-55 T 06-07-2017 CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 Pfam PF00675 Insulinase (Peptidase family M16) 51 192 5.4E-26 T 06-07-2017 IPR011765 Peptidase M16, N-terminal CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 SUPERFAMILY SSF63411 34 245 1.23E-60 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 Gene3D G3DSA:3.30.830.10 265 443 4.0E-29 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 SUPERFAMILY SSF63411 265 449 4.62E-34 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 Gene3D G3DSA:3.30.830.10 30 252 6.0E-57 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 Pfam PF05193 Peptidase M16 inactive domain 200 383 4.3E-32 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAK95_RS13320 02f963673d79f08807e8f3913205cebd 460 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 67 90 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 SUPERFAMILY SSF46689 34 105 8.21E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 SUPERFAMILY SSF48498 107 232 1.33E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS05990 23eda367a823a3505e818c881289d730 241 Gene3D G3DSA:1.10.357.10 88 218 7.2E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 5.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 5.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 Gene3D G3DSA:1.10.10.60 36 87 1.4E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05990 23eda367a823a3505e818c881289d730 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 87 1.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS23180 69e5b2c0a73fa490da36c3a29af819e5 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 1.7E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS23180 69e5b2c0a73fa490da36c3a29af819e5 331 SUPERFAMILY SSF53850 119 290 5.76E-8 T 06-07-2017 CAK95_RS23180 69e5b2c0a73fa490da36c3a29af819e5 331 PIRSF PIRSF017082 2 331 8.2E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 Pfam PF12848 ABC transporter 214 289 7.0E-24 T 06-07-2017 IPR032781 ABC-transporter extension domain CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 SUPERFAMILY SSF52540 2 81 2.78E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 SUPERFAMILY SSF52540 116 237 2.78E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 Gene3D G3DSA:3.40.50.300 308 514 5.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 Gene3D G3DSA:3.40.50.300 3 272 1.2E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 SMART SM00382 336 503 5.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 SMART SM00382 26 220 3.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 Pfam PF00005 ABC transporter 327 458 3.0E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 Pfam PF00005 ABC transporter 17 175 5.7E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS25805 a7302409ab5f81cae6d2a7ba50486b72 625 SUPERFAMILY SSF52540 296 509 6.07E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.3E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.3E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.3E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 Gene3D G3DSA:2.40.50.100 20 84 2.0E-31 T 06-07-2017 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 85 4.0E-19 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 4.6E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 27.719 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 Pfam PF01016 Ribosomal L27 protein 2 81 2.9E-37 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07260 163397f2b41b10dc0ff6d1b3b04ce121 89 SUPERFAMILY SSF110324 2 83 8.55E-34 T 06-07-2017 CAK95_RS06945 9188a7720a32656ff8d309f3170bfa99 163 SUPERFAMILY SSF141523 10 116 3.4E-24 T 06-07-2017 CAK95_RS06945 9188a7720a32656ff8d309f3170bfa99 163 Pfam PF03734 L,D-transpeptidase catalytic domain 14 117 1.1E-16 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS06945 9188a7720a32656ff8d309f3170bfa99 163 Gene3D G3DSA:2.40.440.10 12 116 9.9E-22 T 06-07-2017 CAK95_RS12020 61f5526d32f33d01cf19bbe36a4e6d98 265 Gene3D G3DSA:3.40.30.10 87 199 7.6E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12020 61f5526d32f33d01cf19bbe36a4e6d98 265 SUPERFAMILY SSF52833 58 158 2.04E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12020 61f5526d32f33d01cf19bbe36a4e6d98 265 Pfam PF05988 Bacterial protein of unknown function (DUF899) 8 240 3.3E-88 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like CAK95_RS20745 11c88a6356c368cb4f473d93f963a2b4 196 Pfam PF07310 PAS domain 2 135 4.8E-36 T 06-07-2017 IPR009922 Protein of unknown function DUF1457 CAK95_RS20745 11c88a6356c368cb4f473d93f963a2b4 196 PIRSF PIRSF031878 1 180 3.4E-44 T 06-07-2017 IPR009922 Protein of unknown function DUF1457 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 Pfam PF01266 FAD dependent oxidoreductase 3 359 8.0E-64 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 Gene3D G3DSA:3.50.50.60 320 363 6.8E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 Gene3D G3DSA:3.50.50.60 133 217 6.8E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 Gene3D G3DSA:3.50.50.60 1 81 6.8E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 SUPERFAMILY SSF51905 334 365 4.14E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06805 c8975f6dee81b5ba0f982be68650643b 366 SUPERFAMILY SSF51905 1 218 4.14E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS28185 250ab42fcc14f4e82731683bac2a8aef 170 SUPERFAMILY SSF88723 38 159 7.57E-20 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS28185 250ab42fcc14f4e82731683bac2a8aef 170 Pfam PF01850 PIN domain 38 159 3.1E-13 T 06-07-2017 IPR002716 PIN domain CAK95_RS28185 250ab42fcc14f4e82731683bac2a8aef 170 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 37 165 10.19 T 06-07-2017 IPR022907 VapC family GO:0004540 CAK95_RS28185 250ab42fcc14f4e82731683bac2a8aef 170 Gene3D G3DSA:3.40.50.1010 38 167 4.3E-14 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 358 378 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 SUPERFAMILY SSF53067 250 491 1.6E-76 T 06-07-2017 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 PIRSF PIRSF000538 2 493 6.1E-166 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 Gene3D G3DSA:3.30.420.40 250 491 3.2E-90 T 06-07-2017 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 448 7.4E-55 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 491 5.8E-205 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 Hamap MF_00186 Glycerol kinase [glpK]. 2 494 53.17 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 SUPERFAMILY SSF53067 5 251 3.61E-90 T 06-07-2017 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 248 1.4E-66 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAK95_RS03860 faf22a4b5ce2d7db213ec56208983d4c 494 Gene3D G3DSA:3.30.420.40 3 249 3.1E-94 T 06-07-2017 CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 114 356 5.4E-102 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 SUPERFAMILY SSF52540 111 340 1.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 Hamap MF_02040 Iron-sulfur cluster carrier protein. 109 357 38.261 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 SUPERFAMILY SSF117916 3 85 1.5E-13 T 06-07-2017 CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 Gene3D G3DSA:3.40.50.300 109 356 3.5E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 Pfam PF01883 Domain of unknown function DUF59 5 74 5.8E-17 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAK95_RS19825 91d503013ef208e3d3fe815bf28e1693 376 ProSitePatterns PS01215 Mrp family signature. 220 236 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 CAK95_RS05235 112c268042baf8e109ea3cf544b2412e 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 11 146 3.9E-34 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAK95_RS05235 112c268042baf8e109ea3cf544b2412e 153 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAK95_RS05235 112c268042baf8e109ea3cf544b2412e 153 Gene3D G3DSA:3.40.930.10 1 146 6.3E-44 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAK95_RS05235 112c268042baf8e109ea3cf544b2412e 153 SUPERFAMILY SSF55804 1 145 3.79E-42 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CAK95_RS05235 112c268042baf8e109ea3cf544b2412e 153 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 146 1.1E-46 T 06-07-2017 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 SUPERFAMILY SSF54373 291 474 2.85E-57 T 06-07-2017 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 Gene3D G3DSA:3.50.50.60 188 314 7.0E-123 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 Gene3D G3DSA:3.50.50.60 467 534 7.0E-123 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 Gene3D G3DSA:3.50.50.60 3 127 7.0E-123 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 Pfam PF00732 GMC oxidoreductase 6 296 5.8E-81 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 SUPERFAMILY SSF51905 470 533 2.3E-89 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 SUPERFAMILY SSF51905 4 284 2.3E-89 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 Pfam PF05199 GMC oxidoreductase 388 526 4.5E-39 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS12280 59fd770c137837d8bbaa3e708bd75258 536 PIRSF PIRSF000137 1 536 2.4E-151 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Gene3D G3DSA:2.40.30.10 102 195 1.3E-22 T 06-07-2017 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Pfam PF00175 Oxidoreductase NAD-binding domain 206 309 6.2E-24 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Gene3D G3DSA:3.10.20.30 1 87 6.2E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 SUPERFAMILY SSF63380 101 195 1.15E-20 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 81 4.0E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Pfam PF00970 Oxidoreductase FAD-binding domain 104 195 2.4E-11 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 SUPERFAMILY SSF52343 200 328 3.8E-39 T 06-07-2017 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 Gene3D G3DSA:3.40.50.80 200 329 2.1E-38 T 06-07-2017 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 242 253 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 295 303 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 230 239 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 205 224 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 130 140 3.4E-12 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 189 198 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 295 303 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 205 224 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 230 239 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 4.0E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS12485 a35c30a26d39e9b924212279864834a4 337 SUPERFAMILY SSF54292 1 87 2.49E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Pfam PF02803 Thiolase, C-terminal domain 271 391 2.3E-51 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 390 8.1E-142 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 SUPERFAMILY SSF53901 4 268 1.03E-86 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Gene3D G3DSA:3.40.47.10 276 391 4.2E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Gene3D G3DSA:3.40.47.10 142 193 4.2E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Gene3D G3DSA:3.40.47.10 4 124 2.7E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Gene3D G3DSA:3.40.47.10 194 275 2.7E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 3.9E-107 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 PIRSF PIRSF000429 1 392 1.7E-121 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 SUPERFAMILY SSF53901 271 391 2.02E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10345 48b0200dbb543cc5832b7271be3e5d58 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 SUPERFAMILY SSF54373 179 287 1.29E-25 T 06-07-2017 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 Pfam PF01494 FAD binding domain 2 171 1.7E-17 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 Pfam PF01494 FAD binding domain 293 357 1.1E-8 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 SUPERFAMILY SSF51905 1 174 1.38E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 SUPERFAMILY SSF51905 283 361 1.38E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 7.2E-20 T 06-07-2017 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.2E-20 T 06-07-2017 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 7.2E-20 T 06-07-2017 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 7.2E-20 T 06-07-2017 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 Gene3D G3DSA:3.50.50.60 283 358 3.4E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09855 3e74f6a5d0ab37e7c1f5a06519dcd7d7 418 Gene3D G3DSA:3.50.50.60 2 179 3.4E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11270 80d5b27dd0a3fef25df1eff45dec68c6 571 Pfam PF02690 Na+/Pi-cotransporter 19 154 1.7E-36 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CAK95_RS11270 80d5b27dd0a3fef25df1eff45dec68c6 571 Pfam PF02690 Na+/Pi-cotransporter 184 265 1.5E-14 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CAK95_RS13360 5e2bfc223c83b19ce3a1d721d0338d9c 148 Pfam PF14437 MafB19-like deaminase 2 148 2.7E-30 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAK95_RS13360 5e2bfc223c83b19ce3a1d721d0338d9c 148 Gene3D G3DSA:3.40.140.10 3 146 8.1E-56 T 06-07-2017 CAK95_RS13360 5e2bfc223c83b19ce3a1d721d0338d9c 148 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 46.766 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAK95_RS13360 5e2bfc223c83b19ce3a1d721d0338d9c 148 SUPERFAMILY SSF53927 5 147 1.1E-51 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS13360 5e2bfc223c83b19ce3a1d721d0338d9c 148 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAK95_RS01400 4d9c92c8da15aa9be1ae9233d336f1b9 246 Gene3D G3DSA:3.90.226.10 5 226 5.0E-36 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS01400 4d9c92c8da15aa9be1ae9233d336f1b9 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 216 1.6E-25 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS01400 4d9c92c8da15aa9be1ae9233d336f1b9 246 SUPERFAMILY SSF52096 5 233 2.93E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07075 31f7c1fcba6eaa86d793136c6fa830a1 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 124 2.8E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS07075 31f7c1fcba6eaa86d793136c6fa830a1 131 SUPERFAMILY SSF54593 1 127 6.44E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS07075 31f7c1fcba6eaa86d793136c6fa830a1 131 Gene3D G3DSA:3.10.180.10 1 127 5.7E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS16330 35f1d90729af795777d848ab8b4654c9 281 Pfam PF12697 Alpha/beta hydrolase family 51 274 5.1E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16330 35f1d90729af795777d848ab8b4654c9 281 Gene3D G3DSA:3.40.50.1820 47 280 3.0E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16330 35f1d90729af795777d848ab8b4654c9 281 SUPERFAMILY SSF53474 46 279 3.12E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16415 79c9b267662e06b670f32509fe69e8ee 510 Gene3D G3DSA:2.40.160.20 451 507 9.7E-4 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS16415 79c9b267662e06b670f32509fe69e8ee 510 Gene3D G3DSA:2.40.160.20 302 338 9.7E-4 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS16415 79c9b267662e06b670f32509fe69e8ee 510 Pfam PF10082 Putative beta-barrel porin 2 134 509 6.6E-125 T 06-07-2017 IPR018759 Putative beta-barrel porin 2 CAK95_RS19145 f79ca943bacc2c3c8708a538f9aff88f 455 SUPERFAMILY SSF47384 226 293 7.06E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19145 f79ca943bacc2c3c8708a538f9aff88f 455 SMART SM00387 345 455 1.0E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19145 f79ca943bacc2c3c8708a538f9aff88f 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 453 2.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19145 f79ca943bacc2c3c8708a538f9aff88f 455 SUPERFAMILY SSF55874 309 453 5.89E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19145 f79ca943bacc2c3c8708a538f9aff88f 455 Gene3D G3DSA:3.30.565.10 310 454 2.0E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 Pfam PF13408 Recombinase zinc beta ribbon domain 310 360 2.1E-8 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 Pfam PF00239 Resolvase, N terminal domain 3 143 1.1E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 SMART SM00857 3 144 6.7E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 SUPERFAMILY SSF53041 1 143 2.22E-27 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 Gene3D G3DSA:3.40.50.1390 1 108 1.3E-21 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK95_RS02695 87573914254a29dd22bb630cce6b3526 552 Pfam PF07508 Recombinase 173 286 7.1E-23 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK95_RS05450 596a4a1988b2cc52d65295ee1091c5eb 252 Pfam PF00106 short chain dehydrogenase 6 177 2.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS05450 596a4a1988b2cc52d65295ee1091c5eb 252 Gene3D G3DSA:3.40.50.720 1 199 1.2E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05450 596a4a1988b2cc52d65295ee1091c5eb 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 179 0.0019 T 06-07-2017 CAK95_RS05450 596a4a1988b2cc52d65295ee1091c5eb 252 SUPERFAMILY SSF51735 1 185 3.73E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16395 7a6542a9b2f0cb462e2780fcbf64cf92 401 Pfam PF00155 Aminotransferase class I and II 32 393 3.2E-82 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS16395 7a6542a9b2f0cb462e2780fcbf64cf92 401 Gene3D G3DSA:3.90.1150.10 277 400 1.1E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS16395 7a6542a9b2f0cb462e2780fcbf64cf92 401 Gene3D G3DSA:3.40.640.10 45 276 1.2E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS16395 7a6542a9b2f0cb462e2780fcbf64cf92 401 SUPERFAMILY SSF53383 1 399 2.89E-115 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 Gene3D G3DSA:1.10.10.10 3 71 1.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 SMART SM00895 79 209 4.2E-14 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 SUPERFAMILY SSF48008 76 215 1.99E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 SUPERFAMILY SSF46785 4 73 3.02E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 4.5E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 SMART SM00345 11 69 8.0E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 Pfam PF07729 FCD domain 79 207 9.0E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS01215 dc0d2f036c8a5f260f68dce6984242f9 234 Gene3D G3DSA:1.20.120.530 72 215 6.4E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 283 299 8.2E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 268 283 8.2E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 SUPERFAMILY SSF46689 200 250 1.09E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 Pfam PF12833 Helix-turn-helix domain 222 300 7.4E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 SMART SM00342 216 299 4.8E-30 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 SUPERFAMILY SSF46689 252 300 5.38E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 Gene3D G3DSA:1.10.10.60 198 252 6.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 Gene3D G3DSA:1.10.10.60 253 300 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 SUPERFAMILY SSF51182 34 80 4.75E-5 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 Pfam PF12852 Cupin 2 183 5.8E-39 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAK95_RS11545 49626ee851d8ef557d7809d2524d7bba 325 Gene3D G3DSA:2.60.120.10 29 78 5.2E-4 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 Gene3D G3DSA:1.10.357.10 17 202 1.3E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.3E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 SUPERFAMILY SSF46689 11 81 4.89E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03890 0ed5a0fd23091e0dd340400a6c5cb6e2 225 SUPERFAMILY SSF48498 88 190 4.45E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 183 82.917 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 156 1.1E-16 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 SUPERFAMILY SSF69118 3 174 1.22E-45 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 Pfam PF02627 Carboxymuconolactone decarboxylase family 101 175 7.7E-14 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 3 175 1.1E-68 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS10920 4d69bf11e539dd54711901031c079f93 183 Gene3D G3DSA:1.20.1290.10 3 174 4.7E-53 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 Gene3D G3DSA:3.40.190.10 94 180 1.1E-16 T 06-07-2017 CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 Gene3D G3DSA:3.40.190.10 181 265 2.3E-14 T 06-07-2017 CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 Pfam PF03466 LysR substrate binding domain 90 296 1.2E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 SUPERFAMILY SSF46785 4 113 1.14E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 9.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 SUPERFAMILY SSF53850 91 295 3.8E-37 T 06-07-2017 CAK95_RS26185 e293d3ba7acf20dc10c8710b523af08d 298 Gene3D G3DSA:1.10.10.10 4 89 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 PIRSF PIRSF002122 2 156 1.5E-62 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 5.4E-70 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 SUPERFAMILY SSF47973 4 149 6.54E-65 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.6E-69 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 Gene3D G3DSA:1.10.455.10 7 156 2.0E-70 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21245 9eb182ae80b001c7c995500b4f2ff537 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.935 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 7.0E-22 T 06-07-2017 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 7.0E-22 T 06-07-2017 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 7.0E-22 T 06-07-2017 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 7.0E-22 T 06-07-2017 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 7.0E-22 T 06-07-2017 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 SUPERFAMILY SSF51905 11 177 9.29E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 SUPERFAMILY SSF51905 278 365 9.29E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 Gene3D G3DSA:3.50.50.60 11 182 1.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 Gene3D G3DSA:3.50.50.60 278 361 1.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 Pfam PF01494 FAD binding domain 11 331 3.4E-30 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS14180 abd1f6a3296a51f140628fa33a3d1cf8 404 SUPERFAMILY SSF54373 183 280 1.35E-16 T 06-07-2017 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 Pfam PF03702 Uncharacterised protein family (UPF0075) 6 370 2.0E-92 T 06-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 SUPERFAMILY SSF53067 74 119 6.47E-18 T 06-07-2017 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 SUPERFAMILY SSF53067 6 37 6.47E-18 T 06-07-2017 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 SUPERFAMILY SSF53067 149 343 6.47E-18 T 06-07-2017 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 5 374 37.065 T 06-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAK95_RS25030 d267cf9665cd763d2949cb5a2245aee1 383 Gene3D G3DSA:3.30.420.40 5 204 1.1E-64 T 06-07-2017 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 267 309 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 Pfam PF12852 Cupin 2 196 3.7E-36 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 Gene3D G3DSA:1.10.10.60 210 267 1.8E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 Gene3D G3DSA:1.10.10.60 268 315 2.4E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 SUPERFAMILY SSF46689 266 315 3.58E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 SMART SM00342 230 313 4.7E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 SUPERFAMILY SSF46689 213 263 1.25E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 Pfam PF12833 Helix-turn-helix domain 236 314 1.1E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 7.1E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS09595 c4e478e8d28673dde2eff231e06115cc 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 7.1E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS23895 cdee03fc7ecb53fef899577f7e8a01bc 254 SUPERFAMILY SSF64167 2 252 3.4E-74 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAK95_RS23895 cdee03fc7ecb53fef899577f7e8a01bc 254 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 241 2.2E-59 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAK95_RS23895 cdee03fc7ecb53fef899577f7e8a01bc 254 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 254 33.436 T 06-07-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAK95_RS23895 cdee03fc7ecb53fef899577f7e8a01bc 254 Gene3D G3DSA:3.40.1210.10 2 251 2.9E-76 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAK95_RS23895 cdee03fc7ecb53fef899577f7e8a01bc 254 Pfam PF01975 Survival protein SurE 3 187 7.2E-53 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAK95_RS07150 57d8006ac74ff76e9a659f62ccab6347 381 Pfam PF02515 CoA-transferase family III 5 368 2.0E-112 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS07150 57d8006ac74ff76e9a659f62ccab6347 381 Gene3D G3DSA:3.40.50.10540 3 212 1.5E-98 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS07150 57d8006ac74ff76e9a659f62ccab6347 381 Gene3D G3DSA:3.40.50.10540 301 369 1.5E-98 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS07150 57d8006ac74ff76e9a659f62ccab6347 381 Gene3D G3DSA:3.30.1540.10 228 300 1.6E-21 T 06-07-2017 CAK95_RS07150 57d8006ac74ff76e9a659f62ccab6347 381 SUPERFAMILY SSF89796 2 370 5.36E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS02510 691ba897f10c5d87c8a646c91944231a 173 Gene3D G3DSA:1.10.10.10 96 149 7.7E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02510 691ba897f10c5d87c8a646c91944231a 173 SUPERFAMILY SSF46955 95 150 4.39E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS02510 691ba897f10c5d87c8a646c91944231a 173 Pfam PF12728 Helix-turn-helix domain 96 146 2.5E-7 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 Gene3D G3DSA:3.40.190.10 3 89 1.6E-27 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 156 178 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 SUPERFAMILY SSF53850 5 186 1.29E-59 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 Gene3D G3DSA:3.30.70.260 191 273 1.3E-25 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 SUPERFAMILY SSF55021 175 274 2.71E-25 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 Gene3D G3DSA:3.40.190.10 90 168 9.5E-27 T 06-07-2017 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 Pfam PF00800 Prephenate dehydratase 6 182 4.8E-55 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK95_RS06745 e08dafaf11f3c11d992c5f7068c6dfd9 285 PIRSF PIRSF001500 1 275 1.4E-63 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 Gene3D G3DSA:3.40.190.10 177 257 8.8E-22 T 06-07-2017 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 Gene3D G3DSA:1.10.10.10 1 87 6.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 Gene3D G3DSA:3.40.190.10 95 176 4.3E-22 T 06-07-2017 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 SUPERFAMILY SSF53850 95 293 1.59E-31 T 06-07-2017 CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 SUPERFAMILY SSF46785 2 86 1.98E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19560 0515b836c6260690e2b30189c9796d62 318 Pfam PF03466 LysR substrate binding domain 95 290 1.8E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 SUPERFAMILY SSF56014 439 582 2.49E-31 T 06-07-2017 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Gene3D G3DSA:3.90.480.10 353 431 1.0E-38 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Gene3D G3DSA:3.90.480.10 107 175 1.0E-38 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 178 336 9.9E-33 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 441 556 2.4E-8 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 PRINTS PR00397 Sirohaem Fe-binding site signature 438 456 3.9E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 PRINTS PR00397 Sirohaem Fe-binding site signature 482 500 3.9E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Gene3D G3DSA:3.30.413.10 437 579 1.0E-31 T 06-07-2017 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 SUPERFAMILY SSF55124 60 184 1.08E-19 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 SUPERFAMILY SSF56014 179 341 4.49E-38 T 06-07-2017 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Gene3D G3DSA:3.30.413.10 178 338 5.3E-35 T 06-07-2017 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 109 167 1.8E-13 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 360 426 6.3E-20 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 482 498 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 87 502 3.8E-130 T 06-07-2017 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like CAK95_RS17025 af10d3dad1bb1e322ba76af5368d0570 586 SUPERFAMILY SSF55124 314 449 1.16E-24 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 SUPERFAMILY SSF51735 13 270 1.0E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 1.8E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 203 0.0036 T 06-07-2017 CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 6.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 6.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 6.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 Gene3D G3DSA:3.40.50.720 12 270 1.0E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17055 82528ac6387435ce355c2faf0b4c6d08 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 269 2.1E-45 T 06-07-2017 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 102 7.1E-6 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Pfam PF07724 AAA domain (Cdc48 subfamily) 202 320 5.0E-36 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Gene3D G3DSA:1.10.8.60 325 434 3.0E-34 T 06-07-2017 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 434 5.5E-180 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 326 394 1.7E-6 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Gene3D G3DSA:3.40.50.300 236 322 3.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Gene3D G3DSA:3.40.50.300 5 110 3.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Gene3D G3DSA:1.10.8.10 111 166 9.5E-23 T 06-07-2017 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Gene3D G3DSA:1.10.8.10 204 231 9.5E-23 T 06-07-2017 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 434 41.187 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 SMART SM01086 326 420 1.3E-19 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 SMART SM00382 49 323 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS08020 31e84aeb605cd86908d7d06c1cab992e 434 SUPERFAMILY SSF52540 6 432 1.4E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 PIRSF PIRSF000103 9 304 5.7E-60 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 SUPERFAMILY SSF48179 175 300 5.21E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 SUPERFAMILY SSF51735 12 174 9.15E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 Gene3D G3DSA:1.10.1040.10 176 298 3.0E-27 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 Gene3D G3DSA:3.40.50.720 12 174 6.5E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 16 29 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 173 1.3E-41 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS11455 2700d40b032f9a6b805967d0dde69aee 312 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 176 297 6.4E-29 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS15290 af3ca2f3526769b6b5a210c65427c3e7 414 Gene3D G3DSA:1.20.1250.20 213 399 6.2E-9 T 06-07-2017 CAK95_RS15290 af3ca2f3526769b6b5a210c65427c3e7 414 Gene3D G3DSA:1.20.1250.20 14 200 6.4E-20 T 06-07-2017 CAK95_RS15290 af3ca2f3526769b6b5a210c65427c3e7 414 Pfam PF07690 Major Facilitator Superfamily 24 321 2.5E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS15290 af3ca2f3526769b6b5a210c65427c3e7 414 TIGRFAM TIGR02718 sider_RhtX_FptX: siderophore transporter, RhtX/FptX family 15 394 2.2E-110 T 06-07-2017 IPR014090 Siderophore transporter, RhtX/FptX family CAK95_RS15290 af3ca2f3526769b6b5a210c65427c3e7 414 SUPERFAMILY SSF103473 4 400 6.41E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 Gene3D G3DSA:3.40.190.10 97 186 1.1E-16 T 06-07-2017 CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 SUPERFAMILY SSF53850 94 294 5.07E-37 T 06-07-2017 CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 Pfam PF03466 LysR substrate binding domain 94 291 1.3E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 Gene3D G3DSA:1.10.10.10 7 92 3.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 Gene3D G3DSA:3.40.190.10 187 249 6.7E-7 T 06-07-2017 CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.7E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28725 3fc26f76de4aee7a4733991aee56a865 301 SUPERFAMILY SSF46785 7 114 4.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 Pfam PF06863 Protein of unknown function (DUF1254) 78 209 2.5E-40 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 Gene3D G3DSA:2.60.120.600 301 480 9.0E-59 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 Pfam PF06742 Protein of unknown function (DUF1214) 347 458 1.3E-37 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 SUPERFAMILY SSF160935 21 480 6.28E-124 T 06-07-2017 CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 Gene3D G3DSA:1.10.3360.10 212 275 1.1E-4 T 06-07-2017 IPR023289 VPA0735-like domain CAK95_RS05090 2334fc7812823de69343fcd569c8c42a 480 Gene3D G3DSA:2.60.40.1610 91 211 1.8E-21 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 Gene3D G3DSA:1.10.10.10 4 144 1.8E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 SUPERFAMILY SSF46785 5 146 2.92E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 Pfam PF12802 MarR family 33 92 1.5E-9 T 06-07-2017 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 7.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 7.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 7.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 7.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00320 beeb64933e68eadbeada668b13639978 177 SMART SM00347 28 128 7.6E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 ProSitePatterns PS00802 Transketolase signature 2. 424 440 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Gene3D G3DSA:3.40.50.970 334 495 3.2E-34 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 SUPERFAMILY SSF52922 491 626 2.75E-36 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 SMART SM00861 318 483 2.8E-65 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Gene3D G3DSA:3.40.50.920 496 626 8.6E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 SUPERFAMILY SSF52518 4 196 1.11E-79 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 SUPERFAMILY SSF52518 241 380 1.11E-79 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 ProSitePatterns PS00801 Transketolase signature 1. 33 52 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Pfam PF02779 Transketolase, pyrimidine binding domain 318 478 3.0E-38 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Pfam PF02780 Transketolase, C-terminal domain 495 618 6.4E-31 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Gene3D G3DSA:3.40.50.970 24 198 7.4E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Gene3D G3DSA:3.40.50.970 240 333 7.4E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 10 623 1.1E-251 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 7 627 45.27 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 8 281 2.7E-120 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04515 a94efd3e824f6cf23d03efb2bf8d71dc 638 SUPERFAMILY SSF52518 316 504 2.03E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02555 51018d46113c2f5276c30ba4366c7363 155 Gene3D G3DSA:1.20.1260.10 31 154 3.2E-22 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS02555 51018d46113c2f5276c30ba4366c7363 155 Pfam PF03713 Domain of unknown function (DUF305) 101 152 1.9E-14 T 06-07-2017 IPR005183 Domain of unknown function DUF305 CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 SMART SM00382 25 379 0.0087 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 SUPERFAMILY SSF52540 6 202 4.43E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 SUPERFAMILY SSF52540 240 377 4.43E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 ProSitePatterns PS00618 RecF protein signature 2. 320 338 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 Gene3D G3DSA:3.40.50.300 6 176 2.0E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 Gene3D G3DSA:3.40.50.300 246 375 2.0E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 373 4.4E-21 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 ProSitePatterns PS00617 RecF protein signature 1. 127 147 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 6 375 2.5E-52 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAK95_RS09445 e9362b102d7c765a819de27155bec0e1 380 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 380 87.586 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAK95_RS03800 8ab627b9f37fd1f67756c539e5661b65 319 Hamap MF_00524 Glucokinase [glk]. 4 319 37.063 T 06-07-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAK95_RS03800 8ab627b9f37fd1f67756c539e5661b65 319 Pfam PF02685 Glucokinase 8 317 8.6E-109 T 06-07-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAK95_RS03800 8ab627b9f37fd1f67756c539e5661b65 319 TIGRFAM TIGR00749 glk: glucokinase 8 313 2.9E-93 T 06-07-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAK95_RS03800 8ab627b9f37fd1f67756c539e5661b65 319 SUPERFAMILY SSF53067 8 316 1.04E-58 T 06-07-2017 CAK95_RS03800 8ab627b9f37fd1f67756c539e5661b65 319 Gene3D G3DSA:3.40.367.20 103 302 2.8E-72 T 06-07-2017 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 SUPERFAMILY SSF81330 13 134 1.57E-29 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 137 1.3E-38 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 06-07-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 139 2.0E-36 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 90 98 8.7E-10 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 99 108 8.7E-10 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 8.7E-10 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS05575 be5db7bd5b38b133a4188e61645f856c 141 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 141 24.159 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK95_RS09090 4fa5db4ec7cd257ff42013376e65457b 179 Pfam PF06347 Bacterial SH3 domain 119 171 5.3E-13 T 06-07-2017 IPR010466 Protein of unknown function DUF1058 CAK95_RS09090 4fa5db4ec7cd257ff42013376e65457b 179 Pfam PF06347 Bacterial SH3 domain 50 106 1.2E-22 T 06-07-2017 IPR010466 Protein of unknown function DUF1058 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 6.5E-38 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 Pfam PF00312 Ribosomal protein S15 8 88 5.3E-36 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 Gene3D G3DSA:1.10.287.10 3 89 2.4E-37 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 SUPERFAMILY SSF47060 5 89 1.97E-33 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-33 T 06-07-2017 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 89 21.508 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09150 f123f2c8be5f7e61973708daa622bd0a 89 SMART SM01387 8 88 8.5E-52 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS04105 2251f9bf1553a256f52759deacec121a 393 SUPERFAMILY SSF53474 48 279 8.47E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS04105 2251f9bf1553a256f52759deacec121a 393 Pfam PF12146 Serine aminopeptidase, S33 98 206 3.0E-9 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK95_RS04105 2251f9bf1553a256f52759deacec121a 393 Gene3D G3DSA:3.40.50.1820 55 293 5.1E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Gene3D G3DSA:1.20.140.10 224 386 6.7E-58 T 06-07-2017 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Gene3D G3DSA:2.40.110.10 127 223 7.0E-32 T 06-07-2017 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 SUPERFAMILY SSF47203 233 386 4.35E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 SUPERFAMILY SSF56645 11 245 2.62E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 222 7.9E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 383 1.1E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 123 5.1E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS09925 ca3bb302d201e963415ac2568a675279 394 Gene3D G3DSA:1.10.540.10 12 124 2.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 Gene3D G3DSA:3.30.70.920 58 140 4.7E-23 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 SMART SM00344 5 114 7.8E-43 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 6.2E-22 T 06-07-2017 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.7E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.7E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.7E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 Pfam PF01037 Lrp/AsnC ligand binding domain 72 143 4.5E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 SUPERFAMILY SSF54909 65 152 8.04E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 SUPERFAMILY SSF46785 4 65 8.57E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 Gene3D G3DSA:1.10.10.10 6 57 7.2E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13760 a7cabba8b4c94144f13124b4d98fbb39 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK95_RS18145 a8af2e0d723f098a1f75ccbae8b9751e 597 SUPERFAMILY SSF64518 3 290 7.06E-16 T 06-07-2017 CAK95_RS18145 a8af2e0d723f098a1f75ccbae8b9751e 597 Pfam PF00700 Bacterial flagellin C-terminal helical region 512 596 6.4E-6 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS18145 a8af2e0d723f098a1f75ccbae8b9751e 597 Gene3D G3DSA:1.20.1330.10 427 548 5.5E-9 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS18145 a8af2e0d723f098a1f75ccbae8b9751e 597 SUPERFAMILY SSF64518 286 596 1.7E-20 T 06-07-2017 CAK95_RS18145 a8af2e0d723f098a1f75ccbae8b9751e 597 Pfam PF00669 Bacterial flagellin N-terminal helical region 15 104 1.6E-5 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS16110 4f136a98ea9740824390c42ffa6e407a 100 SUPERFAMILY SSF54909 1 85 1.72E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS16110 4f136a98ea9740824390c42ffa6e407a 100 Gene3D G3DSA:3.30.70.900 1 86 2.6E-27 T 06-07-2017 CAK95_RS16110 4f136a98ea9740824390c42ffa6e407a 100 Pfam PF07045 Domain of unknown function (DUF1330) 2 94 4.7E-27 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SUPERFAMILY SSF117281 68 198 8.63E-25 T 06-07-2017 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Pfam PF01344 Kelch motif 228 274 7.9E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Pfam PF01344 Kelch motif 276 321 5.6E-8 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Pfam PF01344 Kelch motif 178 225 1.1E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Pfam PF01344 Kelch motif 130 173 5.1E-7 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Gene3D G3DSA:2.120.10.80 209 342 1.3E-35 T 06-07-2017 IPR015915 Kelch-type beta propeller GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 Gene3D G3DSA:2.120.10.80 66 199 2.4E-23 T 06-07-2017 IPR015915 Kelch-type beta propeller GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SMART SM00612 140 186 0.013 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SMART SM00612 92 139 5.0 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SMART SM00612 239 287 4.4E-4 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SMART SM00612 187 238 0.02 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SMART SM00612 288 334 0.001 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 CAK95_RS12815 88ab3fdf6922c4314db8ac1cec2f4691 360 SUPERFAMILY SSF117281 166 345 6.02E-46 T 06-07-2017 CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 SUPERFAMILY SSF52518 17 228 1.24E-14 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 SUPERFAMILY SSF53323 713 954 1.96E-32 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 SUPERFAMILY SSF52922 276 390 5.16E-8 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 Gene3D G3DSA:3.40.50.970 417 479 3.6E-4 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 Gene3D G3DSA:3.40.50.970 488 612 1.2E-7 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 722 909 8.4E-26 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 451 537 3.4E-6 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 SUPERFAMILY SSF52518 431 617 3.46E-14 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12990 2935a8decf7baf1806f7dbcdc2f2cc7b 1157 Gene3D G3DSA:3.40.920.10 716 912 1.2E-21 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS26870 a456b0b71384f7f8301f11c3b2325ac4 798 Gene3D G3DSA:3.90.550.10 185 432 5.7E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26870 a456b0b71384f7f8301f11c3b2325ac4 798 SUPERFAMILY SSF53448 184 420 1.69E-47 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26870 a456b0b71384f7f8301f11c3b2325ac4 798 Pfam PF00535 Glycosyl transferase family 2 187 303 1.8E-25 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS26870 a456b0b71384f7f8301f11c3b2325ac4 798 Pfam PF13524 Glycosyl transferases group 1 699 777 3.9E-9 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 414 433 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.3E-42 T 06-07-2017 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 113 5.3E-10 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 Pfam PF00361 Proton-conducting membrane transporter 126 410 3.1E-65 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 792 914 1.6E-34 T 06-07-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CAK95_RS06445 eb76e385d9e046113f4343fdb4f0453f 938 Pfam PF13244 Domain of unknown function (DUF4040) 610 675 1.0E-18 T 06-07-2017 IPR025383 Domain of unknown function DUF4040 CAK95_RS21345 691e78f1fd387be7eb89240804e2f8cf 119 Gene3D G3DSA:3.30.420.100 24 119 1.0E-38 T 06-07-2017 CAK95_RS21345 691e78f1fd387be7eb89240804e2f8cf 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 119 27.885 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21345 691e78f1fd387be7eb89240804e2f8cf 119 SUPERFAMILY SSF53137 8 117 2.01E-48 T 06-07-2017 CAK95_RS21345 691e78f1fd387be7eb89240804e2f8cf 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 119 2.2E-41 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21345 691e78f1fd387be7eb89240804e2f8cf 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 119 4.7E-39 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS26780 851f2dd749d26fb5bca6f2ece59c87bc 397 Pfam PF13506 Glycosyl transferase family 21 101 252 3.1E-14 T 06-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 CAK95_RS26780 851f2dd749d26fb5bca6f2ece59c87bc 397 SUPERFAMILY SSF53448 48 271 1.13E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26780 851f2dd749d26fb5bca6f2ece59c87bc 397 Gene3D G3DSA:3.90.550.10 59 243 5.6E-10 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS09520 72a1ad6117333a6b95fcef28aafaff03 376 Pfam PF03734 L,D-transpeptidase catalytic domain 232 359 5.9E-17 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS09520 72a1ad6117333a6b95fcef28aafaff03 376 SUPERFAMILY SSF141523 226 360 8.37E-32 T 06-07-2017 CAK95_RS09520 72a1ad6117333a6b95fcef28aafaff03 376 Gene3D G3DSA:2.40.440.10 226 360 2.0E-33 T 06-07-2017 CAK95_RS25315 fa015fd3577fd5d863ab3e8a5108e5fb 374 SUPERFAMILY SSF51679 12 364 6.04E-80 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS25315 fa015fd3577fd5d863ab3e8a5108e5fb 374 Gene3D G3DSA:3.20.20.30 8 364 1.8E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS25315 fa015fd3577fd5d863ab3e8a5108e5fb 374 Pfam PF00296 Luciferase-like monooxygenase 16 334 1.8E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 Gene3D G3DSA:1.10.10.10 30 100 8.7E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 Pfam PF01614 Bacterial transcriptional regulator 162 275 2.7E-18 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 Gene3D G3DSA:3.30.450.40 101 279 6.0E-36 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 SUPERFAMILY SSF46785 33 103 3.28E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 SMART SM00346 31 121 2.0E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 Pfam PF09339 IclR helix-turn-helix domain 33 83 1.6E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS01055 be071d49e8d24db1d2b5673271386dbb 286 SUPERFAMILY SSF55781 105 279 1.96E-35 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 PIRSF PIRSF006443 1 168 1.3E-61 T 06-07-2017 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 74 87 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 Gene3D G3DSA:3.40.980.10 5 158 1.6E-50 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 153 2.6E-35 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 SUPERFAMILY SSF53218 7 171 1.07E-47 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 SMART SM00852 16 160 2.8E-33 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 9 171 8.5E-79 T 06-07-2017 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 CAK95_RS11230 ac1d37247efd826f8b1ca1553cfdd5f1 184 Pfam PF00994 Probable molybdopterin binding domain 16 157 7.2E-37 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.568 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 Gene3D G3DSA:2.30.33.40 1 95 7.1E-41 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 PRINTS PR00297 10kDa chaperonin signature 3 18 8.4E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 PRINTS PR00297 10kDa chaperonin signature 81 94 8.4E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 PRINTS PR00297 10kDa chaperonin signature 25 46 8.4E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 PRINTS PR00297 10kDa chaperonin signature 60 72 8.4E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 SUPERFAMILY SSF50129 1 94 9.14E-37 T 06-07-2017 IPR011032 GroES-like CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 3.5E-37 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS20560 e25f75b22c99da0be76a745f09e58892 104 SMART SM00883 2 94 5.6E-62 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK95_RS12730 e310bfd380f7546a509ff4810497939e 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 331 1.1E-31 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12730 e310bfd380f7546a509ff4810497939e 336 PIRSF PIRSF017082 1 334 6.7E-101 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02710 a8ac7c277c6d704d774de412862094c8 166 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 146 5.4E-8 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS02710 a8ac7c277c6d704d774de412862094c8 166 Gene3D G3DSA:3.40.50.970 2 75 6.4E-6 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02710 a8ac7c277c6d704d774de412862094c8 166 SUPERFAMILY SSF52518 6 148 2.11E-13 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS13715 35fe00bfc08b25c01c8e4cb5bde82562 276 Gene3D G3DSA:3.40.50.620 1 144 8.5E-9 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS13715 35fe00bfc08b25c01c8e4cb5bde82562 276 SUPERFAMILY SSF52402 153 274 4.86E-18 T 06-07-2017 CAK95_RS13715 35fe00bfc08b25c01c8e4cb5bde82562 276 Pfam PF00582 Universal stress protein family 206 274 1.4E-8 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS13715 35fe00bfc08b25c01c8e4cb5bde82562 276 SUPERFAMILY SSF52402 1 144 4.1E-10 T 06-07-2017 CAK95_RS13715 35fe00bfc08b25c01c8e4cb5bde82562 276 Gene3D G3DSA:3.40.50.620 156 274 8.7E-14 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 287 2.8E-60 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 Gene3D G3DSA:3.40.50.720 2 115 7.0E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 4.2E-27 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 SUPERFAMILY SSF51735 102 288 2.07E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 Gene3D G3DSA:3.40.50.720 116 289 4.0E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16175 759ecd36a16e4d4def2c8529809ddda6 327 SUPERFAMILY SSF52283 1 135 2.55E-29 T 06-07-2017 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 SUPERFAMILY SSF53850 89 279 9.95E-19 T 06-07-2017 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 8.5E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 Pfam PF03466 LysR substrate binding domain 88 263 1.2E-19 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 Gene3D G3DSA:3.40.190.10 84 186 1.3E-11 T 06-07-2017 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 Gene3D G3DSA:3.40.190.10 187 238 2.4E-4 T 06-07-2017 CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 Gene3D G3DSA:1.10.10.10 4 83 1.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25715 bed9e4e7429951df55c70e33df39f563 283 SUPERFAMILY SSF46785 5 86 7.07E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01295 acf351411e82770c777934dc13319133 280 Gene3D G3DSA:1.20.144.10 84 246 3.1E-24 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS01295 acf351411e82770c777934dc13319133 280 SUPERFAMILY SSF48317 45 249 8.5E-25 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS01295 acf351411e82770c777934dc13319133 280 Pfam PF01569 PAP2 superfamily 117 246 1.3E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS01295 acf351411e82770c777934dc13319133 280 SMART SM00014 113 240 4.2E-9 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS23020 42cc5693c635e3bd113aa2a53776c51e 386 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 4 349 1.7E-72 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS23020 42cc5693c635e3bd113aa2a53776c51e 386 SUPERFAMILY SSF53756 1 378 2.11E-32 T 06-07-2017 CAK95_RS23020 42cc5693c635e3bd113aa2a53776c51e 386 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 1 380 32.57 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS23020 42cc5693c635e3bd113aa2a53776c51e 386 Pfam PF02684 Lipid-A-disaccharide synthetase 3 351 3.0E-93 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS23020 42cc5693c635e3bd113aa2a53776c51e 386 Gene3D G3DSA:3.40.50.2000 159 348 3.1E-10 T 06-07-2017 CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 SUPERFAMILY SSF46785 9 80 6.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 SMART SM00346 9 98 5.6E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 Gene3D G3DSA:1.10.10.10 3 79 6.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 Pfam PF09339 IclR helix-turn-helix domain 11 61 9.0E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 Gene3D G3DSA:3.30.450.40 84 251 1.2E-45 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 Pfam PF01614 Bacterial transcriptional regulator 126 246 7.4E-29 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS04575 039902e3bc74200d8c026bf3c3911398 252 SUPERFAMILY SSF55781 67 251 1.18E-39 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19890 9bc1609ed3b895ce11b36da44ebeed0e 536 PIRSF PIRSF006060 1 447 2.4E-65 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS19890 9bc1609ed3b895ce11b36da44ebeed0e 536 Pfam PF13520 Amino acid permease 5 416 2.8E-47 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 18 155 3.3E-39 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 Pfam PF02556 Preprotein translocase subunit SecB 18 156 1.4E-51 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 SUPERFAMILY SSF54611 13 153 9.59E-47 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 85 105 3.1E-27 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 25 42 3.1E-27 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 135 153 3.1E-27 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 109 131 3.1E-27 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 Gene3D G3DSA:3.10.420.10 17 161 1.3E-55 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS08050 2e5b9a0e4cc5b0f397b0991fb66bbe33 166 Hamap MF_00821 Protein-export protein SecB [secB]. 1 157 30.822 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 PIRSF PIRSF036382 1 194 3.2E-62 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 Gene3D G3DSA:3.40.50.2300 5 124 2.0E-12 T 06-07-2017 CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 Pfam PF00072 Response regulator receiver domain 7 116 2.1E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 Pfam PF03861 ANTAR domain 135 187 6.8E-21 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 Gene3D G3DSA:1.10.10.10 136 193 2.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 SMART SM01012 132 187 7.6E-25 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK95_RS16990 2d148af51cbf164194d82ff431759074 194 SUPERFAMILY SSF52172 4 187 1.85E-46 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS24890 fac6837b072b350a62f622da4ceb8ce3 498 SUPERFAMILY SSF52129 21 257 1.17E-39 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS24890 fac6837b072b350a62f622da4ceb8ce3 498 Pfam PF00656 Caspase domain 25 249 2.9E-28 T 06-07-2017 CAK95_RS24890 fac6837b072b350a62f622da4ceb8ce3 498 Gene3D G3DSA:3.40.50.1460 23 159 2.8E-18 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS13565 a02c3243f0b0277b94c744c1226bf8cd 182 Pfam PF05239 PRC-barrel domain 57 108 3.5E-10 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS13565 a02c3243f0b0277b94c744c1226bf8cd 182 Gene3D G3DSA:2.30.30.240 58 109 2.5E-9 T 06-07-2017 CAK95_RS13565 a02c3243f0b0277b94c744c1226bf8cd 182 SUPERFAMILY SSF50346 56 115 2.16E-11 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 4.1E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 4.1E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 Gene3D G3DSA:1.10.10.60 245 292 1.3E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 Gene3D G3DSA:2.60.120.280 36 174 2.4E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 Pfam PF12833 Helix-turn-helix domain 213 291 1.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 SUPERFAMILY SSF51215 36 173 2.35E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 SUPERFAMILY SSF46689 245 291 9.41E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20315 1e39587b093b0d947ac315002a8ed148 295 SMART SM00342 207 290 1.5E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 SUPERFAMILY SSF55120 288 523 3.2E-59 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 Gene3D G3DSA:3.10.290.10 218 267 1.1E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 SUPERFAMILY SSF55174 218 269 4.32E-8 T 06-07-2017 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 341 355 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 SMART SM00363 219 286 7.8E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 Pfam PF00849 RNA pseudouridylate synthase 301 455 2.4E-33 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 216 513 2.9E-61 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS21445 cf0d78025cfc51c7553865ae96fbc007 532 Pfam PF01479 S4 domain 219 263 2.7E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Gene3D G3DSA:3.90.226.10 9 195 1.7E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Gene3D G3DSA:3.90.226.10 228 286 1.7E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 SUPERFAMILY SSF48179 490 595 4.0E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 SUPERFAMILY SSF51735 309 487 2.54E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 311 487 1.9E-55 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 490 587 9.4E-16 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Gene3D G3DSA:3.40.50.720 296 491 1.3E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Gene3D G3DSA:1.10.1040.10 492 588 8.3E-15 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 SUPERFAMILY SSF48179 613 703 1.62E-19 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 195 3.9E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 SUPERFAMILY SSF52096 7 293 3.25E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11505 80bb460d01897ca30eaac0d2b54cbe6c 704 Gene3D G3DSA:1.10.1040.10 624 701 9.7E-14 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS28495 e917bf364705ffb510fecefdb3686124 229 SMART SM00382 26 208 5.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28495 e917bf364705ffb510fecefdb3686124 229 Gene3D G3DSA:3.40.50.300 2 220 2.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28495 e917bf364705ffb510fecefdb3686124 229 SUPERFAMILY SSF52540 2 218 6.63E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28495 e917bf364705ffb510fecefdb3686124 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 229 9.4E-99 T 06-07-2017 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CAK95_RS28495 e917bf364705ffb510fecefdb3686124 229 Pfam PF00005 ABC transporter 17 158 1.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Gene3D G3DSA:3.30.470.20 205 450 1.1E-95 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.1E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 SUPERFAMILY SSF51246 332 450 1.46E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 SUPERFAMILY SSF56059 83 348 2.47E-68 T 06-07-2017 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 SUPERFAMILY SSF52440 1 113 2.95E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Pfam PF02785 Biotin carboxylase C-terminal domain 336 447 6.6E-34 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 4.5E-81 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 624 641 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Gene3D G3DSA:3.30.1490.20 130 202 4.6E-32 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Gene3D G3DSA:3.40.50.20 1 129 5.8E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 SMART SM00878 336 447 1.9E-52 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 SUPERFAMILY SSF51230 590 667 8.11E-21 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Gene3D G3DSA:2.40.50.100 598 667 1.7E-22 T 06-07-2017 CAK95_RS21690 7204f1a6edea33ab33330008d2825edb 668 Pfam PF00364 Biotin-requiring enzyme 605 666 7.3E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 580 1.2E-203 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 722 24.765 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 Gene3D G3DSA:1.10.730.10 614 711 6.0E-5 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 722 8.4E-184 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 399 418 6.9E-31 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 48 60 6.9E-31 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 6.9E-31 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 250 265 6.9E-31 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 323 339 6.9E-31 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 Gene3D G3DSA:1.10.3210.10 372 524 3.1E-4 T 06-07-2017 IPR006674 HD domain CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 SUPERFAMILY SSF109604 346 496 6.28E-17 T 06-07-2017 CAK95_RS00515 94f00a6cdefa77f4ca8daf19d0524aa3 724 Pfam PF05746 DALR anticodon binding domain 611 711 7.5E-9 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 Gene3D G3DSA:2.30.330.10 3 78 6.0E-20 T 06-07-2017 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 4 72 1.7E-18 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 PRINTS PR00956 Flagellar motor switch protein FliN signature 36 49 8.4E-10 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 PRINTS PR00956 Flagellar motor switch protein FliN signature 20 36 8.4E-10 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 64 8.4E-10 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 PRINTS PR00956 Flagellar motor switch protein FliN signature 3 19 8.4E-10 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS21715 56feafb7d11067cd8be6d8c270aeb696 80 SUPERFAMILY SSF101801 3 78 1.44E-17 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 SUPERFAMILY SSF54637 15 153 1.27E-43 T 06-07-2017 IPR029069 HotDog domain CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 Pfam PF01515 Phosphate acetyl/butaryl transferase 250 459 1.0E-37 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 SUPERFAMILY SSF53659 174 464 4.03E-62 T 06-07-2017 CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 Gene3D G3DSA:3.40.50.10750 280 436 1.1E-49 T 06-07-2017 CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 Gene3D G3DSA:3.10.129.10 18 150 2.0E-48 T 06-07-2017 IPR029069 HotDog domain CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 Pfam PF01575 MaoC like domain 35 125 7.3E-22 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 PRINTS PR01483 Fatty acid synthase signature 58 79 3.7E-5 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK95_RS16770 fb954b8c681bc52ff38e57a4bfb208f1 474 PRINTS PR01483 Fatty acid synthase signature 36 58 3.7E-5 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK95_RS03225 90b7259d5ca0744ac4a9c8b1306191d0 175 SUPERFAMILY SSF53474 36 105 3.21E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS03225 90b7259d5ca0744ac4a9c8b1306191d0 175 Gene3D G3DSA:3.40.50.1820 51 171 6.3E-8 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16820 d82107a09d06c0b1f8a40b78a4909c08 340 Pfam PF00676 Dehydrogenase E1 component 31 321 3.8E-74 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAK95_RS16820 d82107a09d06c0b1f8a40b78a4909c08 340 Gene3D G3DSA:3.40.50.970 8 333 3.7E-117 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS16820 d82107a09d06c0b1f8a40b78a4909c08 340 SUPERFAMILY SSF52518 12 333 4.21E-94 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS25005 2e7ceb677afde6c4f74fe4a4c2a747d5 492 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 18 483 2.6E-191 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CAK95_RS25005 2e7ceb677afde6c4f74fe4a4c2a747d5 492 SUPERFAMILY SSF101960 39 489 1.14E-137 T 06-07-2017 CAK95_RS25005 2e7ceb677afde6c4f74fe4a4c2a747d5 492 Pfam PF01458 Uncharacterized protein family (UPF0051) 230 463 3.9E-67 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAK95_RS03835 bfa46e09bb9390636635065b70ae7e5c 354 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 160 173 - T 06-07-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CAK95_RS03835 bfa46e09bb9390636635065b70ae7e5c 354 Gene3D G3DSA:3.60.110.10 5 308 5.3E-56 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS03835 bfa46e09bb9390636635065b70ae7e5c 354 SUPERFAMILY SSF56317 6 308 4.97E-76 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS03835 bfa46e09bb9390636635065b70ae7e5c 354 Pfam PF00795 Carbon-nitrogen hydrolase 9 288 1.5E-57 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS03835 bfa46e09bb9390636635065b70ae7e5c 354 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 40 55 - T 06-07-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CAK95_RS25970 0dbc79518f56ccbf9a52541d4386363a 215 Pfam PF04299 Putative FMN-binding domain 3 168 8.2E-55 T 06-07-2017 IPR007396 Transcriptional regulator PAI 2-type CAK95_RS25970 0dbc79518f56ccbf9a52541d4386363a 215 Gene3D G3DSA:2.30.110.10 2 209 1.6E-69 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS25970 0dbc79518f56ccbf9a52541d4386363a 215 SUPERFAMILY SSF50475 11 192 2.27E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS25970 0dbc79518f56ccbf9a52541d4386363a 215 PIRSF PIRSF010372 2 213 3.0E-67 T 06-07-2017 IPR007396 Transcriptional regulator PAI 2-type CAK95_RS18960 c25f5a7acf2a7885de0534c926a03f39 169 SUPERFAMILY SSF51182 2 163 4.0E-37 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS18960 c25f5a7acf2a7885de0534c926a03f39 169 Pfam PF06172 Cupin superfamily (DUF985) 7 143 3.2E-33 T 06-07-2017 IPR009327 Cupin domain of unknown function DUF985 CAK95_RS18960 c25f5a7acf2a7885de0534c926a03f39 169 Gene3D G3DSA:2.60.120.10 2 162 1.4E-36 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 Gene3D G3DSA:1.10.287.90 29 119 3.9E-32 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 40 254 6.6E-60 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 123 142 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 209 226 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 101 121 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 189 209 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 89 101 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 165 186 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 PRINTS PR01166 Cytochrome c oxidase subunit II signature 227 244 1.1E-46 T 06-07-2017 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 190 238 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 Gene3D G3DSA:2.60.40.420 126 257 1.1E-53 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 127 245 7.8E-50 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 29 115 1.3E-29 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 SUPERFAMILY SSF81464 20 118 8.5E-31 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05470 44a04ac1dc2e57ae4ba4741f09e544d9 281 SUPERFAMILY SSF49503 123 260 1.03E-53 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS00805 f234395256497b58393726cf35d26a72 413 SUPERFAMILY SSF51395 246 395 2.35E-77 T 06-07-2017 CAK95_RS00805 f234395256497b58393726cf35d26a72 413 SUPERFAMILY SSF51395 25 217 2.35E-77 T 06-07-2017 CAK95_RS00805 f234395256497b58393726cf35d26a72 413 Pfam PF01070 FMN-dependent dehydrogenase 35 395 9.6E-108 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK95_RS00805 f234395256497b58393726cf35d26a72 413 PIRSF PIRSF000138 9 403 1.1E-102 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAK95_RS00805 f234395256497b58393726cf35d26a72 413 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 296 302 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAK95_RS00805 f234395256497b58393726cf35d26a72 413 Gene3D G3DSA:3.20.20.70 28 397 5.5E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 Pfam PF14461 Prokaryotic E2 family B 26 124 6.8E-13 T 06-07-2017 IPR032701 Prokaryotic E2 family B CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 Gene3D G3DSA:3.10.110.10 51 133 6.0E-5 T 06-07-2017 IPR016135 Ubiquitin-conjugating enzyme/RWD-like CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 Gene3D G3DSA:3.40.50.720 285 429 2.9E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 SUPERFAMILY SSF54495 49 119 4.94E-9 T 06-07-2017 IPR016135 Ubiquitin-conjugating enzyme/RWD-like CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 Pfam PF00899 ThiF family 281 420 2.1E-17 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS11735 5a71db43f3dad82b7321554574e49a9e 574 SUPERFAMILY SSF69572 283 429 1.57E-23 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS08205 0900cef705400c99aacb2057a252c5ff 154 SMART SM00100 15 134 6.0E-4 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS08205 0900cef705400c99aacb2057a252c5ff 154 SUPERFAMILY SSF51206 3 133 2.88E-23 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS08205 0900cef705400c99aacb2057a252c5ff 154 Pfam PF00027 Cyclic nucleotide-binding domain 34 118 1.0E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS08205 0900cef705400c99aacb2057a252c5ff 154 Gene3D G3DSA:2.60.120.10 8 142 3.4E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS10170 f3e35d017d5cc1e54885e3994a843504 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 242 6.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10170 f3e35d017d5cc1e54885e3994a843504 246 SUPERFAMILY SSF161098 48 234 2.35E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10170 f3e35d017d5cc1e54885e3994a843504 246 Gene3D G3DSA:1.10.3720.10 49 242 4.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 5 334 2.5E-86 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 157 312 2.5E-16 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 Gene3D G3DSA:3.30.1330.10 3 146 4.3E-35 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 PIRSF PIRSF005303 1 334 4.3E-75 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 331 27.584 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 SUPERFAMILY SSF56042 150 315 8.07E-35 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 Gene3D G3DSA:3.90.650.10 152 334 1.6E-40 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 143 1.2E-20 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS22460 8a32eb0b7e617ece8186e1416a3a1603 334 SUPERFAMILY SSF55326 6 144 2.84E-27 T 06-07-2017 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:3.30.565.10 728 899 3.4E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:3.40.50.620 250 382 7.6E-15 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SMART SM00388 674 742 2.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 789 895 4.9E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF00582 Universal stress protein family 257 374 1.2E-9 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SMART SM00387 786 898 1.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF13493 Domain of unknown function (DUF4118) 411 515 1.4E-25 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:1.10.287.130 667 727 6.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF13492 GAF domain 537 655 1.2E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF00512 His Kinase A (phospho-acceptor) domain 675 742 2.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SUPERFAMILY SSF55781 518 670 1.57E-7 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SUPERFAMILY SSF52402 258 381 4.27E-14 T 06-07-2017 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:1.20.120.620 407 511 4.6E-28 T 06-07-2017 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 882 895 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 857 875 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 823 837 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 851 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 29 236 1.8E-100 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SUPERFAMILY SSF47384 663 742 3.53E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:3.30.450.40 517 666 6.6E-5 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 Gene3D G3DSA:3.40.50.300 28 235 1.8E-102 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27585 ee7f73d3bc2d082cb52811ec0080b2d9 906 SUPERFAMILY SSF55874 732 899 1.83E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS21800 88607f11fd5cd99791f83fbdb08148d1 135 Gene3D G3DSA:3.40.250.10 8 129 7.8E-30 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21800 88607f11fd5cd99791f83fbdb08148d1 135 SUPERFAMILY SSF52821 12 129 1.96E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21800 88607f11fd5cd99791f83fbdb08148d1 135 SMART SM00450 23 127 2.4E-16 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21800 88607f11fd5cd99791f83fbdb08148d1 135 Pfam PF00581 Rhodanese-like domain 26 123 5.1E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 SUPERFAMILY SSF47616 72 202 5.01E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 Gene3D G3DSA:1.20.1050.10 82 202 6.8E-26 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 75 4.7E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 SUPERFAMILY SSF52833 1 84 2.69E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 Gene3D G3DSA:3.40.30.10 1 80 5.5E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08550 e5cf27ad756cf4e45f0caa30690b2bd4 207 Pfam PF13410 Glutathione S-transferase, C-terminal domain 126 189 1.3E-6 T 06-07-2017 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 SUPERFAMILY SSF55447 179 277 8.77E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 SUPERFAMILY SSF56176 3 174 4.67E-50 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 Gene3D G3DSA:3.30.390.50 180 279 2.1E-23 T 06-07-2017 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 Gene3D G3DSA:3.30.465.10 59 174 1.6E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 8.9E-44 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 275 3.2E-16 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 Gene3D G3DSA:3.30.43.10 2 54 2.1E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS16225 0fcdbec26b22b5f56e6b299cbe3bc4b5 282 SMART SM01092 181 277 9.6E-18 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS12500 b3e1cd1243465359c172b5b9257b87ae 270 Gene3D G3DSA:3.40.50.300 10 227 2.6E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12500 b3e1cd1243465359c172b5b9257b87ae 270 Pfam PF00005 ABC transporter 34 173 1.0E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12500 b3e1cd1243465359c172b5b9257b87ae 270 SMART SM00382 43 224 7.9E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12500 b3e1cd1243465359c172b5b9257b87ae 270 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12500 b3e1cd1243465359c172b5b9257b87ae 270 SUPERFAMILY SSF52540 15 230 3.03E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 Gene3D G3DSA:3.30.1280.10 1 78 3.3E-34 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 78 1.1E-25 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 21.72 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 SUPERFAMILY SSF82697 1 78 2.09E-27 T 06-07-2017 CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 78 4.7E-32 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26525 464e90050d4b71ea0061b37f487b7c20 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 78 1.0E-18 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 PIRSF PIRSF000429 7 372 2.0E-7 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 Gene3D G3DSA:3.40.47.10 26 115 4.4E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 Gene3D G3DSA:3.40.47.10 197 227 4.4E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 SUPERFAMILY SSF53901 183 371 1.07E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 SUPERFAMILY SSF53901 25 120 1.07E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS27425 24b6cdd8c1965a3595f9faf296b69a63 389 Gene3D G3DSA:3.40.47.10 266 366 9.7E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10770 35c34c3a750855edaf88e9ee69a28152 282 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 257 6.4E-124 T 06-07-2017 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 CAK95_RS10770 35c34c3a750855edaf88e9ee69a28152 282 SUPERFAMILY SSF53448 1 258 6.47E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS10770 35c34c3a750855edaf88e9ee69a28152 282 Pfam PF00483 Nucleotidyl transferase 2 213 1.5E-14 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK95_RS10770 35c34c3a750855edaf88e9ee69a28152 282 Gene3D G3DSA:3.90.550.10 1 254 2.4E-61 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS14295 9cdc6a29cadd4063a4f83de27c24342e 305 Gene3D G3DSA:3.40.50.1820 51 303 4.8E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14295 9cdc6a29cadd4063a4f83de27c24342e 305 SUPERFAMILY SSF53474 35 283 1.74E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14295 9cdc6a29cadd4063a4f83de27c24342e 305 Pfam PF07859 alpha/beta hydrolase fold 84 215 3.7E-19 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS07880 e2dfbb8264122a113f3bfaae60bc0ea2 310 Pfam PF16220 Domain of unknown function (DUF4880) 12 52 4.2E-11 T 06-07-2017 IPR032623 FecR, N-terminal CAK95_RS07880 e2dfbb8264122a113f3bfaae60bc0ea2 310 Pfam PF16344 Domain of unknown function (DUF4974) 212 296 9.4E-9 T 06-07-2017 IPR032508 Protein FecR, C-terminal CAK95_RS07880 e2dfbb8264122a113f3bfaae60bc0ea2 310 PIRSF PIRSF018266 3 309 8.5E-73 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAK95_RS07880 e2dfbb8264122a113f3bfaae60bc0ea2 310 Pfam PF04773 FecR protein 104 194 2.7E-17 T 06-07-2017 IPR006860 FecR protein CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 Pfam PF00027 Cyclic nucleotide-binding domain 44 128 3.6E-23 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 SUPERFAMILY SSF51206 18 155 1.09E-37 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 SMART SM00100 25 143 8.2E-22 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 SMART SM00419 179 226 1.1E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 Pfam PF13545 Crp-like helix-turn-helix domain 163 231 1.9E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 Gene3D G3DSA:1.10.10.10 160 235 5.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 93 110 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 SUPERFAMILY SSF46785 162 232 1.34E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12410 109c315aa7ba19bb0907c48ca2e3bb9e 238 Gene3D G3DSA:2.60.120.10 18 157 4.0E-38 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 342 8.1E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 Gene3D G3DSA:3.30.565.10 195 350 1.2E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 SUPERFAMILY SSF55874 189 347 1.44E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 SUPERFAMILY SSF47384 115 188 2.75E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 Gene3D G3DSA:1.10.287.130 118 184 4.5E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 286 2.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 323 2.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 300 2.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 342 2.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 SMART SM00387 235 345 1.8E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS09625 a414687be77bbf0498c2bfead402f462 360 SMART SM00388 127 193 0.0017 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS10260 cbaa5448e7e78a3ec807837ca0562b86 190 SUPERFAMILY SSF52949 3 185 8.75E-59 T 06-07-2017 CAK95_RS10260 cbaa5448e7e78a3ec807837ca0562b86 190 SMART SM00506 14 149 5.8E-42 T 06-07-2017 IPR002589 Macro domain CAK95_RS10260 cbaa5448e7e78a3ec807837ca0562b86 190 Pfam PF01661 Macro domain 31 149 2.1E-39 T 06-07-2017 IPR002589 Macro domain CAK95_RS10260 cbaa5448e7e78a3ec807837ca0562b86 190 Gene3D G3DSA:3.40.220.10 15 185 2.2E-62 T 06-07-2017 CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 PIRSF PIRSF015753 5 323 8.4E-135 T 06-07-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 3.9E-23 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 Gene3D G3DSA:3.40.30.10 41 177 1.2E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 Gene3D G3DSA:1.20.1050.10 178 289 6.7E-28 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 SUPERFAMILY SSF52833 42 160 3.43E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 274 3.3E-14 T 06-07-2017 CAK95_RS00640 65401cb4510879898cbadf4e24daffc4 326 SUPERFAMILY SSF47616 174 322 1.34E-37 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 Gene3D G3DSA:3.40.50.720 1 252 1.5E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 SUPERFAMILY SSF51735 5 252 1.58E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07460 4d7ebe283afc942c3fa5ba9e36b1f178 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 1.2E-60 T 06-07-2017 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 7 258 5.5E-100 T 06-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 Gene3D G3DSA:3.30.540.10 6 154 7.1E-41 T 06-07-2017 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 Gene3D G3DSA:3.40.190.80 155 258 4.8E-21 T 06-07-2017 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 Pfam PF00459 Inositol monophosphatase family 7 256 5.9E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 SUPERFAMILY SSF56655 6 258 3.93E-71 T 06-07-2017 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 6.9E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 6.9E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 6.9E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 178 199 6.9E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS16490 2562f1dec9a83fd75f28cca894fcc1fa 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 6.9E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS00980 a6ae549b8a1c8d70449a7afe1778783d 309 SUPERFAMILY SSF161098 69 296 8.5E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00980 a6ae549b8a1c8d70449a7afe1778783d 309 SUPERFAMILY SSF160964 29 59 1.11E-6 T 06-07-2017 CAK95_RS00980 a6ae549b8a1c8d70449a7afe1778783d 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 307 1.7E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00980 a6ae549b8a1c8d70449a7afe1778783d 309 Gene3D G3DSA:1.10.3720.10 75 305 3.6E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00980 a6ae549b8a1c8d70449a7afe1778783d 309 Gene3D G3DSA:1.20.58.370 30 58 2.7E-4 T 06-07-2017 CAK95_RS18605 629fa378c516c4d9d426134873495f15 344 SUPERFAMILY SSF46626 181 289 2.22E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS18605 629fa378c516c4d9d426134873495f15 344 SUPERFAMILY SSF46626 86 167 5.27E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS18605 629fa378c516c4d9d426134873495f15 344 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 191 279 7.4E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS18605 629fa378c516c4d9d426134873495f15 344 Gene3D G3DSA:1.10.760.10 54 169 2.7E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS18605 629fa378c516c4d9d426134873495f15 344 Gene3D G3DSA:1.10.760.10 186 283 2.8E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 70 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 SMART SM00411 6 95 1.9E-33 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 Gene3D G3DSA:4.10.520.10 5 96 7.3E-30 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 PRINTS PR01727 Prokaryotic integration host factor signature 79 93 2.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 2.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 2.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 5 97 8.8E-39 T 06-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 SUPERFAMILY SSF47729 6 98 1.0E-28 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 Pfam PF00216 Bacterial DNA-binding protein 6 95 1.1E-28 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22520 4dbc4482f899a28c15ef78a380ffc059 109 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 4 100 27.992 T 06-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CAK95_RS14665 75838e4786e059e8364f06c8c9b8b504 95 Gene3D G3DSA:1.10.1470.10 32 94 7.8E-22 T 06-07-2017 IPR008462 CsbD-like CAK95_RS14665 75838e4786e059e8364f06c8c9b8b504 95 SUPERFAMILY SSF69047 31 94 3.53E-19 T 06-07-2017 IPR008462 CsbD-like CAK95_RS14665 75838e4786e059e8364f06c8c9b8b504 95 Pfam PF05532 CsbD-like 33 84 2.3E-14 T 06-07-2017 IPR008462 CsbD-like CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1083 1095 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF04563 RNA polymerase beta subunit 27 505 8.5E-34 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:3.90.1100.10 453 599 3.1E-149 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:3.90.1100.10 19 157 3.1E-149 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:3.90.1100.10 667 721 3.1E-149 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.30.150.10 600 664 1.2E-28 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF04565 RNA polymerase Rpb2, domain 3 521 589 3.7E-32 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF00562 RNA polymerase Rpb2, domain 6 726 1281 4.0E-168 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:3.90.1110.10 159 236 1.2E-69 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:3.90.1110.10 354 452 1.2E-69 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1359 12.46 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF04561 RNA polymerase Rpb2, domain 2 362 462 1.0E-18 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF04561 RNA polymerase Rpb2, domain 2 158 229 6.0E-6 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF10385 RNA polymerase beta subunit external 1 domain 599 664 6.5E-26 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.40.50.100 723 799 1.0E-30 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.40.270.10 800 827 1.2E-88 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.40.270.10 1080 1259 1.2E-88 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.40.50.150 834 944 2.6E-58 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Gene3D G3DSA:2.40.50.150 1065 1079 2.6E-58 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 SUPERFAMILY SSF64484 12 232 0.0 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 SUPERFAMILY SSF64484 1059 1360 0.0 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 SUPERFAMILY SSF64484 351 946 0.0 T 06-07-2017 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1355 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21220 e0e65cbed928995965647e4cc5a79356 1372 Pfam PF04560 RNA polymerase Rpb2, domain 7 1283 1357 1.9E-26 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS12075 6c37f2460ffda46c633b1f99feff2bbe 96 Pfam PF13627 Prokaryotic lipoprotein-attachment site 25 46 1.2E-7 T 06-07-2017 IPR032831 Prokaryotic lipoprotein-attachment site CAK95_RS16315 f1d019435f850b907c095e45bc892e09 230 SUPERFAMILY SSF53850 15 217 1.36E-26 T 06-07-2017 CAK95_RS16315 f1d019435f850b907c095e45bc892e09 230 Gene3D G3DSA:3.40.190.10 106 177 6.5E-6 T 06-07-2017 CAK95_RS16315 f1d019435f850b907c095e45bc892e09 230 SMART SM00062 8 223 4.8E-16 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS16315 f1d019435f850b907c095e45bc892e09 230 Gene3D G3DSA:3.40.190.10 15 105 3.1E-9 T 06-07-2017 CAK95_RS16315 f1d019435f850b907c095e45bc892e09 230 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 15 212 1.1E-14 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS13290 c513d37e4f830a2a827eb744527ddc5b 132 Gene3D G3DSA:3.40.50.2300 7 129 1.0E-36 T 06-07-2017 CAK95_RS13290 c513d37e4f830a2a827eb744527ddc5b 132 SUPERFAMILY SSF52172 7 126 4.84E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS13290 c513d37e4f830a2a827eb744527ddc5b 132 SMART SM00448 7 121 4.9E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS13290 c513d37e4f830a2a827eb744527ddc5b 132 Pfam PF00072 Response regulator receiver domain 9 122 1.8E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04355 028a9b8ca95b8a222268a7d2cb8377a1 326 PIRSF PIRSF017082 1 326 5.9E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS04355 028a9b8ca95b8a222268a7d2cb8377a1 326 Gene3D G3DSA:3.40.190.10 129 219 5.2E-5 T 06-07-2017 CAK95_RS04355 028a9b8ca95b8a222268a7d2cb8377a1 326 SUPERFAMILY SSF53850 113 286 6.03E-15 T 06-07-2017 CAK95_RS04355 028a9b8ca95b8a222268a7d2cb8377a1 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 5.5E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17090 8febc78734156d88313c7712cbc4574c 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 264 2.7E-70 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS17090 8febc78734156d88313c7712cbc4574c 265 SUPERFAMILY SSF52096 7 265 5.83E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS17090 8febc78734156d88313c7712cbc4574c 265 Gene3D G3DSA:3.90.226.10 8 206 7.7E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS17090 8febc78734156d88313c7712cbc4574c 265 Gene3D G3DSA:1.10.12.10 207 265 4.0E-22 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS17090 8febc78734156d88313c7712cbc4574c 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 PIRSF PIRSF005227 1 268 1.1E-78 T 06-07-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 Gene3D G3DSA:3.40.50.720 4 136 1.8E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 3 266 31.943 T 06-07-2017 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 Pfam PF01958 Domain of unknown function DUF108 168 254 1.8E-30 T 06-07-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 119 1.1E-14 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 SUPERFAMILY SSF51735 4 151 3.11E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 SUPERFAMILY SSF55347 122 237 1.05E-27 T 06-07-2017 CAK95_RS26450 7ed52086f3ad449fb48bf0a417de1a3a 268 Gene3D G3DSA:3.30.360.10 137 237 2.5E-35 T 06-07-2017 CAK95_RS01430 f4f0b9f33bd2a8bba883a220663c2f00 67 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 57 2.0E-12 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK95_RS01430 f4f0b9f33bd2a8bba883a220663c2f00 67 Pfam PF12728 Helix-turn-helix domain 12 57 3.2E-11 T 06-07-2017 CAK95_RS01430 f4f0b9f33bd2a8bba883a220663c2f00 67 Gene3D G3DSA:1.10.10.60 15 35 9.0E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27260 784a09046f587013d54ab245040f53a9 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 324 6.7E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 Gene3D G3DSA:3.40.50.300 3 243 1.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 SUPERFAMILY SSF52540 4 245 1.49E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 Pfam PF00005 ABC transporter 21 175 5.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 SMART SM00382 29 222 1.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00910 88a50d835be8bee3e711306884d68376 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 245 1.2E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS01915 66b7ea0ac090f8ec9f92798498d86edb 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 192 9.7E-45 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS01915 66b7ea0ac090f8ec9f92798498d86edb 205 SUPERFAMILY SSF51391 4 198 2.75E-61 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS01915 66b7ea0ac090f8ec9f92798498d86edb 205 Pfam PF02581 Thiamine monophosphate synthase/TENI 13 181 1.7E-49 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS01915 66b7ea0ac090f8ec9f92798498d86edb 205 Gene3D G3DSA:3.20.20.70 6 199 9.7E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 Pfam PF00696 Amino acid kinase family 26 267 1.1E-49 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 Gene3D G3DSA:3.40.1160.10 24 290 9.0E-105 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 SUPERFAMILY SSF53633 3 290 1.7E-90 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 PIRSF PIRSF000728 10 291 1.3E-107 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 Hamap MF_00082_B Acetylglutamate kinase [argB]. 23 291 36.004 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS12175 fd4aeb4b18203a229a6044d7edb806f2 291 TIGRFAM TIGR00761 argB: acetylglutamate kinase 26 266 4.3E-76 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS24770 6eb61a9d68da548388b33445cd52a521 344 Gene3D G3DSA:3.20.20.210 151 326 3.6E-7 T 06-07-2017 CAK95_RS24770 6eb61a9d68da548388b33445cd52a521 344 SUPERFAMILY SSF51726 18 334 1.15E-10 T 06-07-2017 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 ProDom PD019076 METALLOTHIONEIN METALLOTHIONEIN ZINC METAL-BINDING CADMIUM CLUSTER MT METAL-THIOLATE COPPER SMTA 6 55 2.0E-10 T 06-07-2017 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 Gene3D G3DSA:2.30.170.10 5 57 9.6E-20 T 06-07-2017 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 Pfam PF02069 Prokaryotic metallothionein 6 55 1.6E-18 T 06-07-2017 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 PRINTS PR00859 Prokaryote metallothionein signature 4 20 1.2E-6 T 06-07-2017 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 PRINTS PR00859 Prokaryote metallothionein signature 22 38 1.2E-6 T 06-07-2017 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 CAK95_RS25190 a69403b367250b872d70ddffe8727810 57 SUPERFAMILY SSF57868 7 57 4.47E-14 T 06-07-2017 IPR017854 Metallothionein domain GO:0046872 CAK95_RS02145 155cd03d2c1a791d18484550a82551ab 336 Gene3D G3DSA:3.20.20.30 1 327 6.6E-87 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02145 155cd03d2c1a791d18484550a82551ab 336 Pfam PF00296 Luciferase-like monooxygenase 7 297 9.9E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02145 155cd03d2c1a791d18484550a82551ab 336 SUPERFAMILY SSF51679 1 328 1.18E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS19150 506238c44f3a9864c386d3ca9c1cd6c3 159 Pfam PF16998 17 kDa outer membrane surface antigen 81 156 2.1E-8 T 06-07-2017 IPR032635 Surface antigen domain CAK95_RS19150 506238c44f3a9864c386d3ca9c1cd6c3 159 Pfam PF05433 Glycine zipper 2TM domain 31 73 1.7E-8 T 06-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 CAK95_RS19150 506238c44f3a9864c386d3ca9c1cd6c3 159 PIRSF PIRSF002721 2 159 1.2E-47 T 06-07-2017 IPR016364 Surface antigen, Rickettsia type CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 Pfam PF09130 Domain of unknown function (DUF1932) 193 263 8.2E-17 T 06-07-2017 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 Gene3D G3DSA:3.40.50.720 4 172 1.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 SUPERFAMILY SSF51735 4 164 8.56E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 SUPERFAMILY SSF48179 166 271 5.19E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 Gene3D G3DSA:1.10.1040.10 173 270 2.3E-35 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS17210 0d28108adf97b4c0e7ab403f6414fe70 296 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 1.7E-9 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAK95_RS16040 a1c1dff8985b5d4e18ceb721758367f6 408 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 296 8.8E-14 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS16040 a1c1dff8985b5d4e18ceb721758367f6 408 SUPERFAMILY SSF111369 66 301 1.23E-55 T 06-07-2017 CAK95_RS16040 a1c1dff8985b5d4e18ceb721758367f6 408 Gene3D G3DSA:2.40.50.100 182 216 1.7E-16 T 06-07-2017 CAK95_RS16040 a1c1dff8985b5d4e18ceb721758367f6 408 Gene3D G3DSA:2.40.50.100 75 107 1.7E-16 T 06-07-2017 CAK95_RS16040 a1c1dff8985b5d4e18ceb721758367f6 408 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 376 2.9E-81 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS09875 471e75502b8e6c32fb993d7de11da341 150 Gene3D G3DSA:2.60.120.10 11 127 6.9E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS09875 471e75502b8e6c32fb993d7de11da341 150 SUPERFAMILY SSF51182 21 112 5.06E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS09875 471e75502b8e6c32fb993d7de11da341 150 Pfam PF07883 Cupin domain 40 107 1.5E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS16630 618b0e7753f4bd1ef103cb203fa13e42 277 SUPERFAMILY SSF52540 30 252 2.78E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16630 618b0e7753f4bd1ef103cb203fa13e42 277 Pfam PF00005 ABC transporter 45 184 4.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16630 618b0e7753f4bd1ef103cb203fa13e42 277 SMART SM00382 54 234 1.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16630 618b0e7753f4bd1ef103cb203fa13e42 277 Gene3D G3DSA:3.40.50.300 28 232 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23030 d12da4699cafc130840ddad3b878c80b 95 Pfam PF04226 Transglycosylase associated protein 38 83 1.8E-6 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 8.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 SUPERFAMILY SSF52172 5 187 9.96E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 Gene3D G3DSA:1.10.10.10 128 227 2.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 Pfam PF00072 Response regulator receiver domain 8 116 9.3E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 SMART SM00448 6 116 1.8E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 SMART SM00862 151 225 2.2E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS27580 546d6478cbc86c03f5ea16576eb809f8 229 Gene3D G3DSA:3.40.50.2300 4 126 5.8E-40 T 06-07-2017 CAK95_RS20460 49c130d6ccbb76c7139a7774114f83fc 251 Pfam PF13505 Outer membrane protein beta-barrel domain 14 251 6.0E-20 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS20460 49c130d6ccbb76c7139a7774114f83fc 251 Gene3D G3DSA:2.40.160.20 26 251 1.1E-39 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS20460 49c130d6ccbb76c7139a7774114f83fc 251 SUPERFAMILY SSF56925 26 251 1.53E-31 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 Gene3D G3DSA:1.10.10.10 144 221 6.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 Gene3D G3DSA:2.60.120.10 35 112 1.5E-9 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 SUPERFAMILY SSF51206 35 111 5.89E-14 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 SMART SM00419 163 212 1.2E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 169 185 2.2E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 200 2.2E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 Pfam PF13545 Crp-like helix-turn-helix domain 144 218 2.3E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS10790 01ebce0783d5da3335ee1bb3761342f2 222 SUPERFAMILY SSF46785 144 221 6.49E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 16 108 1.1E-14 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 14 277 25.226 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 SUPERFAMILY SSF48179 170 277 1.53E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 PIRSF PIRSF000193 14 279 3.6E-61 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 16 277 6.1E-75 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 Gene3D G3DSA:3.40.50.720 16 168 9.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 Gene3D G3DSA:1.10.3730.10 170 277 1.2E-34 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 SUPERFAMILY SSF51735 17 168 7.89E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13535 dfddc471e7fe84e066ba2ae37d4c7e7d 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 171 277 9.9E-34 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAK95_RS21205 404797b2c1e6c40447e45780d41be151 399 SUPERFAMILY SSF51726 9 388 3.4E-51 T 06-07-2017 CAK95_RS21205 404797b2c1e6c40447e45780d41be151 399 Gene3D G3DSA:3.20.20.210 7 393 8.8E-72 T 06-07-2017 CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 Gene3D G3DSA:3.30.450.40 82 252 3.9E-20 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 Gene3D G3DSA:1.10.10.10 4 75 3.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 Pfam PF01614 Bacterial transcriptional regulator 135 249 2.6E-8 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 SUPERFAMILY SSF46785 10 75 2.73E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 SUPERFAMILY SSF55781 86 251 8.5E-20 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 Pfam PF09339 IclR helix-turn-helix domain 12 60 4.9E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS28555 f47898eb9c9e03fa12eb5c50b81ec7b7 258 SMART SM00346 10 98 8.6E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Pfam PF13087 AAA domain 924 1102 1.9E-26 T 06-07-2017 CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Pfam PF12705 PD-(D/E)XK nuclease superfamily 110 226 1.8E-4 T 06-07-2017 CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Pfam PF13482 RNase_H superfamily 322 505 5.4E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Pfam PF13604 AAA domain 750 896 1.3E-10 T 06-07-2017 CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 11 505 9.1E-73 T 06-07-2017 IPR019993 RecB family nuclease, TM0106, putative CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 SUPERFAMILY SSF52540 748 1107 6.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Gene3D G3DSA:3.40.50.300 944 1103 2.5E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19355 e1449d5b3f5ac00c48dd32c1db73ce90 1131 Gene3D G3DSA:3.40.50.300 750 943 1.4E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21580 741052d5a03dc4d85c7ab94e3b994f29 80 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 39 3.2E-7 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK95_RS21580 741052d5a03dc4d85c7ab94e3b994f29 80 SUPERFAMILY SSF47598 3 57 5.56E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK95_RS04015 f13954a256f6686716aa9c0ac3e17478 148 Pfam PF11014 Protein of unknown function (DUF2852) 7 135 3.6E-48 T 06-07-2017 IPR021273 Protein of unknown function DUF2852 CAK95_RS14895 a2626b0f6c7c7b4f56ba9c81c1d10da5 350 Gene3D G3DSA:3.20.20.210 122 328 1.0E-12 T 06-07-2017 CAK95_RS14895 a2626b0f6c7c7b4f56ba9c81c1d10da5 350 SUPERFAMILY SSF51726 25 329 1.8E-16 T 06-07-2017 CAK95_RS04430 2f5378651f32aa4b21d9a4b84d7be69d 234 Gene3D G3DSA:3.90.850.10 23 231 2.1E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS04430 2f5378651f32aa4b21d9a4b84d7be69d 234 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 223 3.9E-55 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS04430 2f5378651f32aa4b21d9a4b84d7be69d 234 SUPERFAMILY SSF56529 24 229 1.57E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Pfam PF00501 AMP-binding enzyme 21 440 2.8E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Gene3D G3DSA:3.30.300.30 435 534 2.7E-26 T 06-07-2017 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Gene3D G3DSA:3.40.50.980 188 341 5.0E-36 T 06-07-2017 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Gene3D G3DSA:2.30.38.10 360 434 2.2E-14 T 06-07-2017 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Gene3D G3DSA:3.40.50.980 12 187 3.0E-28 T 06-07-2017 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 SUPERFAMILY SSF56801 7 538 6.41E-131 T 06-07-2017 CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS15810 86dd18517132171459b21c2e3265358c 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 524 1.4E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 SUPERFAMILY SSF52518 1 182 4.91E-43 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 519 2.4E-35 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 SUPERFAMILY SSF52518 350 532 5.18E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 316 2.2E-21 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Gene3D G3DSA:3.40.50.1220 184 364 9.5E-36 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 1.9E-42 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Gene3D G3DSA:3.40.50.970 1 170 2.2E-43 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 SUPERFAMILY SSF52467 184 348 8.39E-33 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS25690 471c02de8b5846da39fbe3a2a7ba3249 538 Gene3D G3DSA:3.40.50.970 365 528 5.6E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 SUPERFAMILY SSF88946 6 89 9.81E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 32 63 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 Gene3D G3DSA:1.10.10.10 101 160 1.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 SUPERFAMILY SSF88659 98 159 3.92E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 Gene3D G3DSA:1.10.1740.10 6 78 3.1E-22 T 06-07-2017 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 Pfam PF08281 Sigma-70, region 4 103 155 1.3E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 158 2.1E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11075 20ae80ac5f7277379a9552d2a3bbfadb 182 Pfam PF04542 Sigma-70 region 2 15 77 3.9E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07950 a290a7e765d233966ef63894c6d68857 526 Gene3D G3DSA:3.60.21.10 227 518 2.1E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS07950 a290a7e765d233966ef63894c6d68857 526 Gene3D G3DSA:3.60.21.10 145 192 2.1E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS07950 a290a7e765d233966ef63894c6d68857 526 SUPERFAMILY SSF56300 145 511 8.85E-32 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS07950 a290a7e765d233966ef63894c6d68857 526 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 47 138 2.0E-17 T 06-07-2017 IPR032093 Phospholipase D, N-terminal CAK95_RS07950 a290a7e765d233966ef63894c6d68857 526 Pfam PF09423 PhoD-like phosphatase 154 496 4.9E-75 T 06-07-2017 IPR018946 Alkaline phosphatase D-related CAK95_RS12130 a2900cef3d270c3e040441f53bf4c43e 247 Pfam PF01553 Acyltransferase 59 182 2.2E-17 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK95_RS12130 a2900cef3d270c3e040441f53bf4c43e 247 SUPERFAMILY SSF69593 7 228 2.09E-37 T 06-07-2017 CAK95_RS12130 a2900cef3d270c3e040441f53bf4c43e 247 Gene3D G3DSA:3.40.1130.10 64 210 9.1E-16 T 06-07-2017 CAK95_RS12130 a2900cef3d270c3e040441f53bf4c43e 247 SMART SM00563 71 185 1.0E-27 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 Pfam PF01546 Peptidase family M20/M25/M40 91 415 1.1E-36 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 Gene3D G3DSA:3.40.630.10 361 420 2.1E-116 T 06-07-2017 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 Gene3D G3DSA:3.40.630.10 14 235 2.1E-116 T 06-07-2017 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 SUPERFAMILY SSF55031 223 339 5.41E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 20 417 8.7E-138 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 PIRSF PIRSF001235 16 423 7.3E-136 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 SUPERFAMILY SSF53187 13 233 1.74E-94 T 06-07-2017 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 SUPERFAMILY SSF53187 346 418 1.74E-94 T 06-07-2017 CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 Gene3D G3DSA:3.30.70.360 236 335 2.2E-35 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS26730 11bf2397dce2f9281562027a941ac683 426 Pfam PF07687 Peptidase dimerisation domain 220 320 3.5E-7 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Gene3D G3DSA:2.40.50.140 1 66 8.4E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.2E-14 T 06-07-2017 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 SUPERFAMILY SSF46929 157 204 8.5E-9 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 SMART SM00278 108 127 130.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 SMART SM00278 73 92 13.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 204 29.469 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 SUPERFAMILY SSF50249 1 63 4.45E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Gene3D G3DSA:1.10.150.20 68 140 6.3E-28 T 06-07-2017 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 SUPERFAMILY SSF47781 66 134 3.24E-20 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Pfam PF07499 RuvA, C-terminal domain 159 203 3.8E-10 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Gene3D G3DSA:1.10.8.10 156 204 1.3E-10 T 06-07-2017 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 186 1.0E-40 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAK95_RS04065 f282dadb4880bffb23836425c779906b 205 Pfam PF01330 RuvA N terminal domain 1 62 2.7E-20 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK95_RS09880 ad70a2b1286d9924ddc1838254c09d36 392 Gene3D G3DSA:3.40.50.2300 28 221 5.1E-47 T 06-07-2017 CAK95_RS09880 ad70a2b1286d9924ddc1838254c09d36 392 SUPERFAMILY SSF53822 29 391 1.15E-91 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS09880 ad70a2b1286d9924ddc1838254c09d36 392 Pfam PF13458 Periplasmic binding protein 29 366 6.7E-77 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS07290 2ce62d30e6e0b1b248f9b8a8755fe369 701 Gene3D G3DSA:2.40.170.20 177 701 1.2E-75 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS07290 2ce62d30e6e0b1b248f9b8a8755fe369 701 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 176 6.2E-18 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS07290 2ce62d30e6e0b1b248f9b8a8755fe369 701 SUPERFAMILY SSF56935 26 701 1.13E-97 T 06-07-2017 CAK95_RS07290 2ce62d30e6e0b1b248f9b8a8755fe369 701 Pfam PF00593 TonB dependent receptor 446 700 3.6E-25 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS07290 2ce62d30e6e0b1b248f9b8a8755fe369 701 Gene3D G3DSA:2.170.130.10 26 176 7.3E-27 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS01435 5acc89edf5a4940e6e526480df74e145 210 Pfam PF13730 Helix-turn-helix domain 29 75 1.4E-8 T 06-07-2017 CAK95_RS01435 5acc89edf5a4940e6e526480df74e145 210 Gene3D G3DSA:1.10.10.10 10 78 2.4E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01435 5acc89edf5a4940e6e526480df74e145 210 SUPERFAMILY SSF46785 10 90 1.3E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11295 ef4e6a75c4e8f362f395937a1f209c2d 218 Pfam PF13462 Thioredoxin 51 213 5.2E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11295 ef4e6a75c4e8f362f395937a1f209c2d 218 SUPERFAMILY SSF52833 42 213 3.06E-43 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11295 ef4e6a75c4e8f362f395937a1f209c2d 218 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 35 7.3E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS11295 ef4e6a75c4e8f362f395937a1f209c2d 218 Gene3D G3DSA:3.40.30.10 147 210 1.3E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11295 ef4e6a75c4e8f362f395937a1f209c2d 218 Gene3D G3DSA:3.40.30.10 40 137 7.1E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS13980 61221a30547f1d05fead7885a96e6080 311 Pfam PF05675 Protein of unknown function (DUF817) 46 282 4.4E-102 T 06-07-2017 IPR008535 Protein of unknown function DUF817 CAK95_RS13980 61221a30547f1d05fead7885a96e6080 311 PIRSF PIRSF009141 35 302 7.6E-101 T 06-07-2017 IPR008535 Protein of unknown function DUF817 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 Hamap MF_01685 Ferredoxin--NADP reductase. 7 332 39.143 T 06-07-2017 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 SUPERFAMILY SSF51905 8 311 1.46E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 Gene3D G3DSA:3.50.50.60 250 327 3.3E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 Gene3D G3DSA:3.50.50.60 6 128 3.3E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 291 4.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.4E-12 T 06-07-2017 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 2.4E-12 T 06-07-2017 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.4E-12 T 06-07-2017 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 3.5E-15 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 3.5E-15 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 3.5E-15 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 3.5E-15 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS03725 cf1a23fcd44fcafd9a12281fdae54d57 342 Gene3D G3DSA:3.50.50.60 130 222 9.9E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26140 c045b9db821a8c9ed12c9c6df6e4bc26 335 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 176 9.8E-25 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CAK95_RS11640 c7671095f75b530fca32fbfb2b5f1d3c 272 SUPERFAMILY SSF51197 1 258 4.12E-58 T 06-07-2017 CAK95_RS11640 c7671095f75b530fca32fbfb2b5f1d3c 272 Gene3D G3DSA:2.60.120.620 4 216 1.8E-52 T 06-07-2017 CAK95_RS11640 c7671095f75b530fca32fbfb2b5f1d3c 272 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 13 203 1.6E-26 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK95_RS11040 ba8ab58062860c9f661f9f02fbd1d860 161 Pfam PF00692 dUTPase 21 153 1.4E-31 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAK95_RS11040 ba8ab58062860c9f661f9f02fbd1d860 161 Gene3D G3DSA:2.70.40.10 11 155 3.6E-53 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS11040 ba8ab58062860c9f661f9f02fbd1d860 161 SUPERFAMILY SSF51283 10 154 2.22E-50 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS11040 ba8ab58062860c9f661f9f02fbd1d860 161 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 7 154 33.732 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAK95_RS11040 ba8ab58062860c9f661f9f02fbd1d860 161 TIGRFAM TIGR00576 dut: dUTP diphosphatase 16 153 1.3E-54 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAK95_RS12260 729e645da4ff2912e8d0a79018092b81 151 SUPERFAMILY SSF54637 8 149 1.87E-15 T 06-07-2017 IPR029069 HotDog domain CAK95_RS12260 729e645da4ff2912e8d0a79018092b81 151 Gene3D G3DSA:3.10.129.10 8 149 1.2E-15 T 06-07-2017 IPR029069 HotDog domain CAK95_RS12260 729e645da4ff2912e8d0a79018092b81 151 Pfam PF01575 MaoC like domain 50 116 2.2E-5 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS02815 9831683f72fbbac17182e48ac07b982b 156 Pfam PF08592 Domain of unknown function (DUF1772) 18 140 5.1E-21 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 Gene3D G3DSA:1.10.10.10 11 81 1.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 SMART SM00895 90 214 1.8E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.2E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.2E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 SUPERFAMILY SSF46785 14 110 1.16E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 SMART SM00345 22 80 2.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 Gene3D G3DSA:1.20.120.530 84 224 8.9E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 3.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 Pfam PF07729 FCD domain 91 212 2.6E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS16980 9a2faa8c19cb4e551999e0a63a279c6f 226 SUPERFAMILY SSF48008 87 220 1.41E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 Pfam PF13671 AAA domain 341 482 2.0E-22 T 06-07-2017 CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 SUPERFAMILY SSF56112 7 301 4.25E-23 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 Gene3D G3DSA:3.90.1200.10 131 289 1.8E-7 T 06-07-2017 CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 Pfam PF01636 Phosphotransferase enzyme family 106 288 9.3E-10 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 Gene3D G3DSA:3.40.50.300 339 482 1.2E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03905 0dd31391cd7771a5c4bd3c46afaa3a77 513 SUPERFAMILY SSF52540 336 486 1.97E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 2.5E-52 T 06-07-2017 CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 SUPERFAMILY SSF51735 11 251 9.81E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 9.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15850 82aff25996c231c08120bac255f47a1b 251 Gene3D G3DSA:3.40.50.720 11 250 4.3E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09940 75e2e74203e9d8aa6c985b278d9c2d1a 211 Gene3D G3DSA:1.10.10.60 8 70 3.6E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09940 75e2e74203e9d8aa6c985b278d9c2d1a 211 Gene3D G3DSA:1.10.357.10 75 204 2.3E-47 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS09940 75e2e74203e9d8aa6c985b278d9c2d1a 211 SUPERFAMILY SSF46689 8 90 6.67E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09940 75e2e74203e9d8aa6c985b278d9c2d1a 211 SUPERFAMILY SSF48498 86 200 1.37E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS09940 75e2e74203e9d8aa6c985b278d9c2d1a 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.4E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS06725 1371ae15a5d23256c9bb7b1f56de7d30 633 SUPERFAMILY SSF53850 70 621 5.97E-113 T 06-07-2017 CAK95_RS06725 1371ae15a5d23256c9bb7b1f56de7d30 633 PIRSF PIRSF002741 21 625 7.3E-92 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS06725 1371ae15a5d23256c9bb7b1f56de7d30 633 Gene3D G3DSA:3.10.105.10 350 590 1.0E-45 T 06-07-2017 CAK95_RS06725 1371ae15a5d23256c9bb7b1f56de7d30 633 Gene3D G3DSA:3.40.190.10 181 349 5.1E-32 T 06-07-2017 CAK95_RS06725 1371ae15a5d23256c9bb7b1f56de7d30 633 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 122 535 9.2E-76 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS17505 ef15259d8493b9b1b256b75546ab239e 324 SUPERFAMILY SSF53850 111 288 1.32E-14 T 06-07-2017 CAK95_RS17505 ef15259d8493b9b1b256b75546ab239e 324 PIRSF PIRSF017082 2 324 3.0E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17505 ef15259d8493b9b1b256b75546ab239e 324 Gene3D G3DSA:3.40.190.10 127 249 3.3E-9 T 06-07-2017 CAK95_RS17505 ef15259d8493b9b1b256b75546ab239e 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 8.2E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 Gene3D G3DSA:3.40.50.720 1 162 4.0E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 9.7E-40 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 PIRSF PIRSF000103 1 295 6.9E-71 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 SUPERFAMILY SSF48179 162 289 4.19E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 SUPERFAMILY SSF51735 1 163 2.71E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 283 3.0E-15 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS10135 251847bd8d36ea576e1bfb19b5bda1fc 295 Gene3D G3DSA:1.10.1040.10 164 293 1.8E-24 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS24390 c9f301530c6825b5216b4607a37ee38d 149 SUPERFAMILY SSF55166 40 126 4.71E-6 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS24390 c9f301530c6825b5216b4607a37ee38d 149 Gene3D G3DSA:3.30.1380.10 49 129 7.6E-6 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 SUPERFAMILY SSF56645 11 258 1.23E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Gene3D G3DSA:1.10.540.10 5 130 2.8E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 SUPERFAMILY SSF47203 243 398 9.99E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 393 4.5E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Gene3D G3DSA:1.20.140.10 235 400 4.8E-51 T 06-07-2017 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Gene3D G3DSA:2.40.110.10 131 234 1.6E-43 T 06-07-2017 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 128 6.8E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS17185 62ac198ea5e86eca47e97ec4cc6a9c18 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 227 3.6E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 Pfam PF07729 FCD domain 90 219 4.7E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 SMART SM00345 22 80 2.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 SUPERFAMILY SSF48008 86 225 5.49E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 Gene3D G3DSA:1.20.120.530 84 224 1.7E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 SMART SM00895 90 220 4.1E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.1E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 SUPERFAMILY SSF46785 17 84 6.36E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14910 4a827ef8a110b07955c801f2d94fdbcb 239 Gene3D G3DSA:1.10.10.10 13 81 1.5E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10140 4464ab00984f51dd0952228b9900881c 147 Pfam PF03928 Haem-degrading 4 133 2.4E-25 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS10140 4464ab00984f51dd0952228b9900881c 147 SUPERFAMILY SSF143744 2 137 5.49E-35 T 06-07-2017 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 Pfam PF13458 Periplasmic binding protein 24 356 1.5E-67 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 Gene3D G3DSA:3.40.50.2300 24 223 2.1E-68 T 06-07-2017 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 SUPERFAMILY SSF53822 24 358 9.42E-97 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 276 289 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 328 343 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 253 271 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 66 84 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20285 b1cb85fc547aca042f541faa6c8df002 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 87 97 4.3E-28 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS20170 9fccc7c1b943139654af6cc4e059074c 161 SUPERFAMILY SSF54637 5 128 3.86E-28 T 06-07-2017 IPR029069 HotDog domain CAK95_RS20170 9fccc7c1b943139654af6cc4e059074c 161 Pfam PF07977 FabA-like domain 4 122 2.7E-19 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS20170 9fccc7c1b943139654af6cc4e059074c 161 Gene3D G3DSA:3.10.129.10 6 126 1.6E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS00065 116c43f705713c8f2dcca8007aec5142 338 SUPERFAMILY SSF53850 126 299 4.89E-15 T 06-07-2017 CAK95_RS00065 116c43f705713c8f2dcca8007aec5142 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 335 2.8E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00065 116c43f705713c8f2dcca8007aec5142 338 PIRSF PIRSF017082 8 338 8.0E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 SUPERFAMILY SSF52304 3 146 9.29E-63 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 69.929 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 Pfam PF01220 Dehydroquinase class II 4 139 2.0E-60 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 142 4.0E-50 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 PIRSF PIRSF001399 1 147 7.1E-65 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 Gene3D G3DSA:3.40.50.9100 3 145 6.8E-67 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS25240 c444e3f00ff8be73ea14e713c2e0f481 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 2.3E-59 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS11990 e12d852a4dabfaac766e741e1158816f 151 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 151 1.3E-30 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS11990 e12d852a4dabfaac766e741e1158816f 151 Gene3D G3DSA:3.30.530.20 5 151 6.8E-49 T 06-07-2017 IPR023393 START-like domain CAK95_RS11990 e12d852a4dabfaac766e741e1158816f 151 SUPERFAMILY SSF55961 12 151 2.04E-43 T 06-07-2017 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01181 Diaminopimelate decarboxylase signature 194 203 2.3E-11 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01181 Diaminopimelate decarboxylase signature 106 123 2.3E-11 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01181 Diaminopimelate decarboxylase signature 425 447 2.3E-11 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01181 Diaminopimelate decarboxylase signature 337 355 2.3E-11 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 Gene3D G3DSA:3.20.20.10 68 308 7.5E-69 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 68 319 5.7E-39 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 39 450 2.8E-90 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 SUPERFAMILY SSF50621 297 451 1.21E-40 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 SUPERFAMILY SSF51419 58 320 2.13E-62 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 325 435 7.1E-14 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 220 233 5.1E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 108 120 5.1E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 88 106 5.1E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 309 328 5.1E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS11885 6361f828854ce2f6e6b8b448c892f640 454 Gene3D G3DSA:2.40.37.10 309 450 2.9E-38 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS16420 d6f585231ccb2355a798051e76abfb9d 291 Gene3D G3DSA:3.90.550.10 5 276 8.8E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS16420 d6f585231ccb2355a798051e76abfb9d 291 SUPERFAMILY SSF53448 5 278 8.79E-62 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS16420 d6f585231ccb2355a798051e76abfb9d 291 Pfam PF00483 Nucleotidyl transferase 11 271 3.6E-26 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK95_RS16420 d6f585231ccb2355a798051e76abfb9d 291 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 267 4.8E-106 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 Pfam PF01715 IPP transferase 39 283 6.7E-65 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 Gene3D G3DSA:3.40.50.300 2 170 8.8E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 Gene3D G3DSA:3.40.50.300 171 211 7.6E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 303 27.12 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 SUPERFAMILY SSF52540 7 146 1.8E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 Gene3D G3DSA:1.10.287.890 212 283 8.0E-27 T 06-07-2017 CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 SUPERFAMILY SSF52540 130 230 7.54E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 SUPERFAMILY SSF52540 7 38 7.54E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14650 54119232634110fe86ed81aa05deb5dd 304 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 283 2.7E-73 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 SUPERFAMILY SSF54292 4 79 8.52E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 SUPERFAMILY SSF47741 74 152 8.11E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 Gene3D G3DSA:1.10.150.120 76 152 6.8E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 Pfam PF01799 [2Fe-2S] binding domain 74 145 2.3E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 61 2.6E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 Gene3D G3DSA:3.10.20.30 3 75 2.2E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS21185 b678b349da8d63a4983deae771c3917c 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 SUPERFAMILY SSF53822 28 362 4.91E-77 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 Pfam PF13458 Periplasmic binding protein 29 376 3.1E-68 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 Gene3D G3DSA:3.40.50.2300 28 228 2.4E-57 T 06-07-2017 CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 4.7E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 89 4.7E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00395 ef2ea5d2f770ba521c0b1b3d03677d95 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 4.7E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 SUPERFAMILY SSF51730 182 523 1.73E-106 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 821 832 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Gene3D G3DSA:3.20.20.220 182 522 2.4E-96 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Pfam PF00171 Aldehyde dehydrogenase family 563 1017 1.5E-114 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 515 1016 4.1E-186 T 06-07-2017 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Gene3D G3DSA:1.10.2060.10 67 180 1.8E-38 T 06-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 SUPERFAMILY SSF81935 21 180 3.01E-45 T 06-07-2017 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 SUPERFAMILY SSF53720 547 1023 3.4E-124 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Pfam PF01619 Proline dehydrogenase 190 479 1.5E-87 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Gene3D G3DSA:3.40.605.10 555 808 1.1E-73 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 70 179 3.1E-37 T 06-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 Gene3D G3DSA:3.40.309.10 809 999 6.5E-43 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS04690 b805033b8ecb16a5fe2962b8d8cae83e 1038 PIRSF PIRSF000197 9 1035 0.0 T 06-07-2017 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Gene3D G3DSA:1.10.8.60 512 604 1.7E-31 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 TIGRFAM TIGR00763 lon: endopeptidase La 32 790 3.0E-275 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 723 742 1.1E-49 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 746 764 1.1E-49 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 615 631 1.1E-49 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 376 395 1.1E-49 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 693 712 1.1E-49 T 06-07-2017 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Hamap MF_01973 Lon protease [lon]. 30 792 66.485 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 SUPERFAMILY SSF88697 32 219 2.21E-38 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 32 220 1.7E-29 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 SUPERFAMILY SSF52540 334 604 9.49E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 SMART SM00382 368 513 9.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 PIRSF PIRSF001174 11 794 4.2E-282 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Gene3D G3DSA:3.30.230.10 613 791 1.6E-67 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Gene3D G3DSA:3.40.50.300 332 509 3.1E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 590 791 4.5E-84 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 696 704 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 SMART SM00464 29 221 7.4E-41 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 SUPERFAMILY SSF54211 615 790 2.28E-52 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS27090 2bec1c8599f88247e1739d4d7ec18bc4 799 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 372 509 1.9E-20 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS03385 bf7009ba10b9a9f894631c41f06368ff 531 SUPERFAMILY SSF103473 11 400 2.49E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS03385 bf7009ba10b9a9f894631c41f06368ff 531 Gene3D G3DSA:1.20.1250.20 221 397 1.5E-10 T 06-07-2017 CAK95_RS03385 bf7009ba10b9a9f894631c41f06368ff 531 Gene3D G3DSA:1.20.1250.20 8 205 1.4E-19 T 06-07-2017 CAK95_RS03385 bf7009ba10b9a9f894631c41f06368ff 531 Pfam PF05977 Transmembrane secretion effector 5 525 6.0E-168 T 06-07-2017 IPR010290 Transmembrane secretion effector CAK95_RS18785 e4290fea25aab161b31795448ca52f9e 434 SUPERFAMILY SSF103473 29 426 6.28E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS18785 e4290fea25aab161b31795448ca52f9e 434 Pfam PF07690 Major Facilitator Superfamily 49 262 1.4E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS18785 e4290fea25aab161b31795448ca52f9e 434 Gene3D G3DSA:1.20.1250.20 42 217 2.9E-22 T 06-07-2017 CAK95_RS18785 e4290fea25aab161b31795448ca52f9e 434 Gene3D G3DSA:1.20.1250.20 247 433 5.3E-19 T 06-07-2017 CAK95_RS12245 e0045e507a4c3b363a88e356bf46e118 315 Pfam PF00753 Metallo-beta-lactamase superfamily 76 289 1.3E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS12245 e0045e507a4c3b363a88e356bf46e118 315 SMART SM00849 76 289 4.6E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS12245 e0045e507a4c3b363a88e356bf46e118 315 SUPERFAMILY SSF56281 25 300 2.23E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS12245 e0045e507a4c3b363a88e356bf46e118 315 Gene3D G3DSA:3.60.15.10 24 305 3.0E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS17140 ef6668264b2407d7df750c0853f9d1d6 253 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17140 ef6668264b2407d7df750c0853f9d1d6 253 Pfam PF00005 ABC transporter 24 164 1.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17140 ef6668264b2407d7df750c0853f9d1d6 253 SUPERFAMILY SSF52540 4 242 4.2E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17140 ef6668264b2407d7df750c0853f9d1d6 253 SMART SM00382 32 214 3.3E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17140 ef6668264b2407d7df750c0853f9d1d6 253 Gene3D G3DSA:3.40.50.300 4 217 1.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 Gene3D G3DSA:3.40.50.2020 4 161 2.1E-75 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 7 316 48.056 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 316 2.1E-114 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 Gene3D G3DSA:3.40.50.2020 162 289 2.6E-49 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 123 1.3E-49 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 SMART SM01400 7 123 3.1E-79 T 06-07-2017 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 315 5.0E-25 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK95_RS13525 de4efd370500ed0d639280ea3addcf3b 316 SUPERFAMILY SSF53271 72 306 6.63E-62 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS19130 f8b94a139e16e94c3a32f80f863c41ec 225 Pfam PF00881 Nitroreductase family 8 197 1.6E-27 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK95_RS19130 f8b94a139e16e94c3a32f80f863c41ec 225 SUPERFAMILY SSF55469 123 224 1.96E-43 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS19130 f8b94a139e16e94c3a32f80f863c41ec 225 SUPERFAMILY SSF55469 1 62 1.96E-43 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS19130 f8b94a139e16e94c3a32f80f863c41ec 225 Gene3D G3DSA:3.40.109.10 1 62 9.8E-44 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS19130 f8b94a139e16e94c3a32f80f863c41ec 225 Gene3D G3DSA:3.40.109.10 108 221 9.8E-44 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 Gene3D G3DSA:3.40.50.2300 4 124 1.7E-39 T 06-07-2017 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 SUPERFAMILY SSF46894 123 223 1.3E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 Gene3D G3DSA:1.10.10.10 125 225 7.6E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 Pfam PF00072 Response regulator receiver domain 5 113 4.9E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 SUPERFAMILY SSF52172 4 126 1.02E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 SMART SM00862 147 223 6.0E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 SMART SM00448 3 113 5.6E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28250 2345e46061d4c382e834ad7a33c5dd97 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 7.9E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 2.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 271 6.7E-55 T 06-07-2017 CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 Gene3D G3DSA:3.40.50.720 12 271 1.4E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 18 273 2.7E-112 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 7.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 SUPERFAMILY SSF51735 16 272 3.33E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01325 ce44cdbd29ab671d5aa320544fd581b2 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 Gene3D G3DSA:3.40.50.2300 1 122 5.2E-35 T 06-07-2017 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 SMART SM00448 1 112 5.1E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 2.8E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 SMART SM00862 145 221 8.0E-19 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 Gene3D G3DSA:1.10.10.10 123 224 6.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 Pfam PF00072 Response regulator receiver domain 3 112 3.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15220 4d9f47737319f27ba7803bb023ad172e 233 SUPERFAMILY SSF52172 1 174 3.56E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 Gene3D G3DSA:3.40.50.720 5 224 2.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 210 1.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 SUPERFAMILY SSF51735 2 225 3.71E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03875 30ba2bfa4115a9fe3f1bbdabe7b1d066 226 Pfam PF00106 short chain dehydrogenase 7 187 4.0E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 Pfam PF12838 4Fe-4S dicluster domain 61 116 9.2E-13 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 Gene3D G3DSA:1.10.1060.10 14 138 2.8E-24 T 06-07-2017 CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 4.2E-49 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 SUPERFAMILY SSF54862 35 146 1.76E-28 T 06-07-2017 CAK95_RS22870 a0ffe0259a0fedccbe51e35f7b90d019 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 9 159 28.031 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 533 46.415 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 PRINTS PR00702 Acriflavin resistance protein family signature 422 446 1.9E-6 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 PRINTS PR00702 Acriflavin resistance protein family signature 497 520 1.9E-6 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 PRINTS PR00702 Acriflavin resistance protein family signature 394 415 1.9E-6 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 SUPERFAMILY SSF82866 330 528 7.59E-48 T 06-07-2017 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 283 513 3.0E-81 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 46 520 2.4E-152 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 Pfam PF02355 Protein export membrane protein 354 521 3.7E-15 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 Gene3D G3DSA:1.20.1640.10 329 530 1.2E-29 T 06-07-2017 CAK95_RS23870 7cc4d9f0ee0fd3bd9c6a251c7a975f75 534 Pfam PF07549 SecD/SecF GG Motif 40 63 1.7E-5 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 253 387 4.5E-28 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 Gene3D G3DSA:2.40.110.10 132 215 5.1E-21 T 06-07-2017 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 PIRSF PIRSF016578 6 406 6.8E-108 T 06-07-2017 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 Gene3D G3DSA:1.10.540.10 15 122 2.6E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 SUPERFAMILY SSF56645 17 220 2.23E-29 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 Gene3D G3DSA:1.20.140.10 216 405 3.6E-41 T 06-07-2017 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 SUPERFAMILY SSF47203 248 383 1.9E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS00050 1039f066271453a9e6409d2a895ebb7b 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 116 1.4E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 283 325 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 Gene3D G3DSA:1.10.10.60 235 282 8.5E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 313 329 6.3E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 298 313 6.3E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 Pfam PF12833 Helix-turn-helix domain 252 330 2.1E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 SUPERFAMILY SSF46689 282 331 1.52E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 SMART SM00342 246 329 4.6E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 SUPERFAMILY SSF46689 233 279 1.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15480 71b4fdda341ef67cd510cecd6f173d54 333 Gene3D G3DSA:1.10.10.60 283 331 2.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 Gene3D G3DSA:3.40.190.80 167 266 1.8E-35 T 06-07-2017 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 Gene3D G3DSA:3.30.540.10 12 166 4.2E-36 T 06-07-2017 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 12 265 3.6E-71 T 06-07-2017 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 Pfam PF00459 Inositol monophosphatase family 14 253 2.2E-47 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 SUPERFAMILY SSF56655 12 268 1.3E-62 T 06-07-2017 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 225 239 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 6.8E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 6.8E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 6.8E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS15130 6aaf836dfd1f44ccc3efec5193d638f9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 6.8E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS11745 dcba4054d9034e6997e03de34c133e79 310 SMART SM00100 25 142 2.0E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS11745 dcba4054d9034e6997e03de34c133e79 310 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 157 275 7.4E-27 T 06-07-2017 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain CAK95_RS11745 dcba4054d9034e6997e03de34c133e79 310 SUPERFAMILY SSF51206 14 143 1.44E-22 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS11745 dcba4054d9034e6997e03de34c133e79 310 Pfam PF00027 Cyclic nucleotide-binding domain 44 127 5.7E-16 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS11745 dcba4054d9034e6997e03de34c133e79 310 Gene3D G3DSA:2.60.120.10 14 146 8.3E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS24085 69ead9f95abbe1cd02c2cdec9c9071fc 469 Gene3D G3DSA:1.20.1600.10 25 435 7.8E-78 T 06-07-2017 CAK95_RS24085 69ead9f95abbe1cd02c2cdec9c9071fc 469 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 24 447 1.9E-106 T 06-07-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 CAK95_RS24085 69ead9f95abbe1cd02c2cdec9c9071fc 469 SUPERFAMILY SSF56954 8 436 1.31E-88 T 06-07-2017 CAK95_RS24085 69ead9f95abbe1cd02c2cdec9c9071fc 469 Pfam PF02321 Outer membrane efflux protein 249 433 8.9E-29 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS24085 69ead9f95abbe1cd02c2cdec9c9071fc 469 Pfam PF02321 Outer membrane efflux protein 30 229 2.5E-32 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS21705 5bbe46001bbb90439458307d5e363a82 99 SUPERFAMILY SSF54975 4 81 8.29E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK95_RS21705 5bbe46001bbb90439458307d5e363a82 99 Pfam PF00708 Acylphosphatase 8 85 2.3E-22 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK95_RS21705 5bbe46001bbb90439458307d5e363a82 99 Gene3D G3DSA:3.30.70.100 7 84 8.9E-25 T 06-07-2017 CAK95_RS21705 5bbe46001bbb90439458307d5e363a82 99 ProSitePatterns PS00151 Acylphosphatase signature 2. 35 51 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 Pfam PF06426 Serine acetyltransferase, N-terminal 18 120 4.1E-34 T 06-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 211 239 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 SMART SM00971 18 122 3.6E-49 T 06-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 91 251 7.7E-69 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 202 236 5.7E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 SUPERFAMILY SSF51161 15 253 1.66E-60 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 Gene3D G3DSA:2.160.10.10 152 255 2.7E-29 T 06-07-2017 CAK95_RS20710 854781479e6eb96ebe71cf62fe4a7eb7 273 Gene3D G3DSA:1.10.3130.10 15 150 8.5E-44 T 06-07-2017 CAK95_RS08165 bc265b852d788eb0701f56cda015c05b 189 Pfam PF04390 Lipopolysaccharide-assembly 21 181 1.4E-12 T 06-07-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 34 48 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 Gene3D G3DSA:3.20.20.70 4 219 2.6E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 SUPERFAMILY SSF51366 5 216 8.24E-75 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 213 1.6E-84 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 201 7.8E-80 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 PIRSF PIRSF001461 1 225 5.4E-87 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK95_RS20230 01a78d7358b0b4486a2f570029e9eba2 227 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SUPERFAMILY SSF47384 255 326 5.1E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 272 327 5.9E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 3.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 3.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 3.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 3.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SMART SM00388 271 329 1.1E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 473 1.4E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SMART SM00387 368 476 9.5E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 Gene3D G3DSA:3.30.565.10 316 475 7.9E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 Pfam PF00672 HAMP domain 199 267 1.4E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SUPERFAMILY SSF158472 218 268 1.57E-5 T 06-07-2017 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 Gene3D G3DSA:1.10.287.130 261 315 1.7E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SUPERFAMILY SSF55874 323 475 2.49E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11795 3f3d499d61069aec3aebd7c7e20681d2 504 SMART SM00304 218 270 9.3E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 Gene3D G3DSA:3.90.180.10 1 145 2.8E-47 T 06-07-2017 IPR011032 GroES-like CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 SUPERFAMILY SSF50129 1 137 6.7E-40 T 06-07-2017 IPR011032 GroES-like CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 Gene3D G3DSA:3.40.50.720 146 262 1.5E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 SUPERFAMILY SSF51735 111 273 7.89E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 Pfam PF00107 Zinc-binding dehydrogenase 151 272 9.9E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 SMART SM00829 10 322 4.5E-38 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS08760 ae60561f4dfa5cdee0d60fd848c0e2cd 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 5.8E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 SUPERFAMILY SSF51419 36 260 1.34E-55 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 SUPERFAMILY SSF50621 253 392 1.4E-41 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 90 108 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 151 163 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 293 308 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 222 249 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 373 386 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 276 291 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 54 70 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 PRINTS PR00992 Alanine racemase signature 184 195 8.8E-41 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 Pfam PF00842 Alanine racemase, C-terminal domain 260 390 4.1E-35 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 Hamap MF_01201 Alanine racemase. 29 391 28.583 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 59 69 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 TIGRFAM TIGR00492 alr: alanine racemase 34 390 4.6E-72 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 SMART SM01005 260 391 4.8E-54 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 Gene3D G3DSA:2.40.37.10 242 392 1.6E-50 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 Gene3D G3DSA:3.20.20.10 38 241 9.1E-56 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS25945 4c521b8fd81cf3ec095ecfc9ef8d9b75 393 Pfam PF01168 Alanine racemase, N-terminal domain 36 249 2.2E-51 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 SUPERFAMILY SSF55347 139 304 9.81E-51 T 06-07-2017 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Gene3D G3DSA:3.30.360.10 151 300 2.3E-54 T 06-07-2017 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Pfam PF00742 Homoserine dehydrogenase 139 316 1.1E-60 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Pfam PF01842 ACT domain 350 388 3.2E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Gene3D G3DSA:3.40.50.720 4 150 1.5E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 1.4E-13 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 Gene3D G3DSA:3.30.70.260 350 384 3.8E-4 T 06-07-2017 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 SUPERFAMILY SSF51735 4 142 5.91E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 SUPERFAMILY SSF55021 348 420 5.89E-6 T 06-07-2017 CAK95_RS24780 ca3f9d0920f6f02620f11bef2abfcd02 440 PIRSF PIRSF000098 2 439 1.0E-156 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 409 2.5E-71 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 Gene3D G3DSA:1.20.1250.20 250 451 3.6E-17 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 1.1E-7 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 1.1E-7 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 1.1E-7 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 380 399 1.1E-7 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 Pfam PF07690 Major Facilitator Superfamily 11 375 6.7E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 Gene3D G3DSA:1.20.1250.20 10 190 3.8E-29 T 06-07-2017 CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 SUPERFAMILY SSF103473 3 190 1.07E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS26325 60599939892dafc49ff0df39d8a990b9 485 SUPERFAMILY SSF103473 241 449 1.07E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 Pfam PF01494 FAD binding domain 15 346 1.1E-55 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 3.2E-21 T 06-07-2017 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 3.2E-21 T 06-07-2017 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.2E-21 T 06-07-2017 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 3.2E-21 T 06-07-2017 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 Gene3D G3DSA:3.50.50.60 277 356 1.1E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 Gene3D G3DSA:3.50.50.60 13 189 1.1E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 SUPERFAMILY SSF51905 276 386 2.25E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16920 d3bf2cc889f7b63fd3dcd77840d4db98 414 SUPERFAMILY SSF51905 14 184 2.25E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19070 f99bfd5ec44671fa60e46d1ea8caa282 77 Gene3D G3DSA:2.30.170.10 40 67 3.6E-4 T 06-07-2017 CAK95_RS08990 b133a62a392264c60d126c96b60b0208 215 Gene3D G3DSA:3.40.50.620 2 138 8.6E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS08990 b133a62a392264c60d126c96b60b0208 215 Gene3D G3DSA:3.90.1490.10 142 210 1.3E-14 T 06-07-2017 CAK95_RS08990 b133a62a392264c60d126c96b60b0208 215 SUPERFAMILY SSF52402 2 212 8.72E-58 T 06-07-2017 CAK95_RS08990 b133a62a392264c60d126c96b60b0208 215 Pfam PF01902 Diphthamide synthase 3 205 9.6E-22 T 06-07-2017 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CAK95_RS11570 a221c6586f382e62b7ab9ce795a0e4be 247 Gene3D G3DSA:1.10.3720.10 1 235 1.4E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11570 a221c6586f382e62b7ab9ce795a0e4be 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 63 236 8.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11570 a221c6586f382e62b7ab9ce795a0e4be 247 SUPERFAMILY SSF161098 1 242 1.19E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 Gene3D G3DSA:1.10.45.10 432 471 4.0E-12 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 Pfam PF02913 FAD linked oxidases, C-terminal domain 230 470 5.2E-64 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 SUPERFAMILY SSF55103 235 474 1.96E-68 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 SUPERFAMILY SSF56176 19 231 1.26E-68 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 Gene3D G3DSA:3.30.465.10 113 231 1.7E-44 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 Gene3D G3DSA:3.30.43.10 15 112 2.8E-30 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS14545 8d681f693089a034fe2891d7728715c8 475 Pfam PF01565 FAD binding domain 57 193 1.1E-39 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS13920 9927b010282da289427f0291545bab39 308 Gene3D G3DSA:3.40.190.10 92 173 8.0E-20 T 06-07-2017 CAK95_RS13920 9927b010282da289427f0291545bab39 308 SUPERFAMILY SSF53850 88 297 2.71E-39 T 06-07-2017 CAK95_RS13920 9927b010282da289427f0291545bab39 308 Gene3D G3DSA:3.40.190.10 174 262 1.5E-17 T 06-07-2017 CAK95_RS13920 9927b010282da289427f0291545bab39 308 SUPERFAMILY SSF46785 4 83 2.57E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13920 9927b010282da289427f0291545bab39 308 Pfam PF03466 LysR substrate binding domain 87 294 1.0E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS13920 9927b010282da289427f0291545bab39 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13920 9927b010282da289427f0291545bab39 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13920 9927b010282da289427f0291545bab39 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13920 9927b010282da289427f0291545bab39 308 Gene3D G3DSA:1.10.10.10 3 81 1.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13920 9927b010282da289427f0291545bab39 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 SUPERFAMILY SSF75615 121 193 7.32E-20 T 06-07-2017 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Pfam PF13241 Putative NAD(P)-binding 9 121 6.6E-18 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Gene3D G3DSA:3.40.50.720 7 117 2.9E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Gene3D G3DSA:3.30.950.10 338 458 5.1E-31 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Gene3D G3DSA:3.40.1010.10 221 337 5.4E-45 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 224 435 1.1E-48 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Gene3D G3DSA:1.10.8.210 158 188 1.9E-4 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Pfam PF10414 Sirohaem synthase dimerisation region 158 189 1.4E-4 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 PIRSF PIRSF036426 4 472 2.1E-148 T 06-07-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 SUPERFAMILY SSF53790 220 454 4.45E-72 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Pfam PF14824 Sirohaem biosynthesis protein central 126 152 1.7E-6 T 06-07-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 7 194 1.1E-56 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 Gene3D G3DSA:3.30.160.110 119 154 1.8E-16 T 06-07-2017 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 227 241 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 222 454 3.7E-77 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS17040 8aa1648c0b0fdc423f46a4358e2a4933 474 SUPERFAMILY SSF51735 5 118 8.67E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25485 537c97b695f0daee0bf665a03d3e7dd0 122 SUPERFAMILY SSF54909 12 97 2.37E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS25485 537c97b695f0daee0bf665a03d3e7dd0 122 Pfam PF03992 Antibiotic biosynthesis monooxygenase 17 79 9.1E-5 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 297 1.3E-54 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 328 1.8E-31 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 SUPERFAMILY SSF52283 6 132 1.21E-34 T 06-07-2017 CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 155 182 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 SUPERFAMILY SSF51735 106 298 1.36E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 Gene3D G3DSA:3.40.50.720 6 115 3.3E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09085 ec1e6d54e7b21db8a83013d07f115913 333 Gene3D G3DSA:3.40.50.720 116 298 4.1E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11965 6692821dab6547b1023fe5a79bda84ab 215 Gene3D G3DSA:3.40.430.10 9 207 1.9E-40 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS11965 6692821dab6547b1023fe5a79bda84ab 215 Pfam PF01872 RibD C-terminal domain 9 208 1.5E-18 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAK95_RS11965 6692821dab6547b1023fe5a79bda84ab 215 SUPERFAMILY SSF53597 9 201 9.16E-28 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS24920 8c2a72488902788cb1d5a9e92cf791f5 251 PIRSF PIRSF018982 2 250 1.8E-89 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK95_RS24920 8c2a72488902788cb1d5a9e92cf791f5 251 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 9 240 1.1E-88 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 SUPERFAMILY SSF55447 179 270 4.19E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 Gene3D G3DSA:3.30.390.50 179 271 1.5E-14 T 06-07-2017 CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 Gene3D G3DSA:3.30.43.10 1 54 3.4E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 262 7.5E-6 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 2.8E-46 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 SMART SM01092 181 270 8.4E-13 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 Gene3D G3DSA:3.30.465.10 58 174 5.7E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS25415 8f0960333cbdf93443b22a65513c7788 275 SUPERFAMILY SSF56176 1 174 5.45E-51 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 Gene3D G3DSA:3.50.50.60 248 373 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 Gene3D G3DSA:3.50.50.60 96 156 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 Gene3D G3DSA:3.50.50.60 1 42 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 Pfam PF01494 FAD binding domain 3 55 6.4E-6 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 Pfam PF01494 FAD binding domain 111 321 5.5E-14 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 289 9.5E-20 T 06-07-2017 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 258 273 9.5E-20 T 06-07-2017 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 9.5E-20 T 06-07-2017 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 9.5E-20 T 06-07-2017 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 9.5E-20 T 06-07-2017 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 SUPERFAMILY SSF51905 1 149 3.89E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14970 105f69b6b5e8b909c42697f620fd3bbf 378 SUPERFAMILY SSF51905 245 350 3.89E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 148 1.5E-45 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 102 114 4.1E-9 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 115 130 4.1E-9 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 48 60 4.1E-9 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 PIRSF PIRSF001467 2 154 1.7E-30 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 Gene3D G3DSA:2.40.100.10 5 150 2.8E-46 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK95_RS22265 b76d1e1189a22b28c2bbe1b8e011e714 154 SUPERFAMILY SSF50891 10 152 2.78E-50 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK95_RS17350 a6813303f67e2c50590a708975c8efef 217 PIRSF PIRSF009467 1 217 1.3E-62 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAK95_RS17350 a6813303f67e2c50590a708975c8efef 217 Pfam PF01730 UreF 28 174 1.3E-34 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAK95_RS17350 a6813303f67e2c50590a708975c8efef 217 Hamap MF_01385 Urease accessory protein UreF [ureF]. 1 217 28.255 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAK95_RS20065 ae22c313c89e7ac93406ecc205a7c8ed 201 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 6 178 2.3E-54 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAK95_RS20065 ae22c313c89e7ac93406ecc205a7c8ed 201 Pfam PF03641 Possible lysine decarboxylase 49 178 6.1E-38 T 06-07-2017 IPR031100 LOG family CAK95_RS20065 ae22c313c89e7ac93406ecc205a7c8ed 201 SUPERFAMILY SSF102405 2 180 1.13E-58 T 06-07-2017 CAK95_RS20065 ae22c313c89e7ac93406ecc205a7c8ed 201 Gene3D G3DSA:3.40.50.450 1 188 6.7E-64 T 06-07-2017 CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 Gene3D G3DSA:1.20.1050.10 98 210 9.1E-45 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 SUPERFAMILY SSF47616 84 209 1.23E-29 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 209 1.2E-82 T 06-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 Gene3D G3DSA:3.40.30.10 1 97 1.3E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 SUPERFAMILY SSF52833 2 92 2.6E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 82 4.7E-16 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS19980 809170c11237883b72b381d07110b1ab 210 Pfam PF13410 Glutathione S-transferase, C-terminal domain 136 186 3.6E-7 T 06-07-2017 CAK95_RS22535 b64cba570383bc4502a4c17ad57d998d 318 SMART SM00558 104 237 5.0E-4 T 06-07-2017 IPR003347 JmjC domain CAK95_RS22535 b64cba570383bc4502a4c17ad57d998d 318 Gene3D G3DSA:2.60.120.650 42 232 2.7E-19 T 06-07-2017 CAK95_RS22535 b64cba570383bc4502a4c17ad57d998d 318 Pfam PF13621 Cupin-like domain 130 231 9.4E-8 T 06-07-2017 CAK95_RS22535 b64cba570383bc4502a4c17ad57d998d 318 SUPERFAMILY SSF51197 12 293 9.75E-30 T 06-07-2017 CAK95_RS00550 a6330ee5f3152880ed6463f5785ceb0c 291 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 6 243 3.0E-89 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAK95_RS00550 a6330ee5f3152880ed6463f5785ceb0c 291 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 271 40.966 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAK95_RS00550 a6330ee5f3152880ed6463f5785ceb0c 291 Pfam PF01048 Phosphorylase superfamily 6 243 1.3E-38 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS00550 a6330ee5f3152880ed6463f5785ceb0c 291 Gene3D G3DSA:3.40.50.1580 6 264 6.6E-86 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS00550 a6330ee5f3152880ed6463f5785ceb0c 291 SUPERFAMILY SSF53167 6 271 5.29E-88 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 325 70.391 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 Gene3D G3DSA:3.40.47.10 164 324 6.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 Gene3D G3DSA:3.40.47.10 5 163 6.2E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 2.7E-33 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 192 1.9E-32 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 SUPERFAMILY SSF53901 8 324 1.87E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS22515 2057bd59eb177c4d3a6dedac51ebe36b 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 325 4.0E-123 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK95_RS15240 d3214fdb1791c48e3231c5595f1824be 141 Pfam PF01850 PIN domain 2 133 1.7E-15 T 06-07-2017 IPR002716 PIN domain CAK95_RS15240 d3214fdb1791c48e3231c5595f1824be 141 Gene3D G3DSA:3.40.50.1010 1 132 2.8E-7 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS15240 d3214fdb1791c48e3231c5595f1824be 141 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 140 7.7E-37 T 06-07-2017 IPR006226 PIN domain toxin GO:0016788 CAK95_RS15240 d3214fdb1791c48e3231c5595f1824be 141 SUPERFAMILY SSF88723 1 138 9.53E-24 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS15240 d3214fdb1791c48e3231c5595f1824be 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 14.092 T 06-07-2017 IPR022907 VapC family GO:0004540 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 1.6E-43 T 06-07-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.357 T 06-07-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 SMART SM00411 1 91 8.4E-39 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 Gene3D G3DSA:4.10.520.10 1 92 3.1E-33 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 SUPERFAMILY SSF47729 1 92 7.21E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.7E-18 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.7E-18 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.7E-18 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS10945 f4dd66fe131c5736b808d8edb8f64195 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 2.3E-30 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS15305 7009939ffdbbb7f6b53435364e5e2034 216 Gene3D G3DSA:1.20.1050.10 95 206 1.9E-14 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS15305 7009939ffdbbb7f6b53435364e5e2034 216 SUPERFAMILY SSF47616 83 205 2.37E-23 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS15305 7009939ffdbbb7f6b53435364e5e2034 216 Gene3D G3DSA:3.40.30.10 22 94 6.3E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS15305 7009939ffdbbb7f6b53435364e5e2034 216 SUPERFAMILY SSF52833 22 83 5.04E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS15305 7009939ffdbbb7f6b53435364e5e2034 216 Pfam PF02798 Glutathione S-transferase, N-terminal domain 20 81 4.6E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS21410 9f45f5d6e73e7963e7461d88080b3ed9 504 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 22 442 3.1E-150 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Pfam PF00994 Probable molybdopterin binding domain 235 373 8.6E-25 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 SUPERFAMILY SSF63882 52 231 1.15E-47 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Gene3D G3DSA:3.40.980.10 218 387 2.1E-57 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 308 343 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Pfam PF12727 PBP superfamily domain 483 665 5.0E-50 T 06-07-2017 IPR024370 PBP domain CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Gene3D G3DSA:3.90.105.10 187 217 6.9E-21 T 06-07-2017 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Pfam PF03453 MoeA N-terminal region (domain I and II) 53 222 4.9E-32 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 SUPERFAMILY SSF53850 484 682 1.55E-9 T 06-07-2017 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 SMART SM00852 235 374 2.8E-36 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Gene3D G3DSA:2.170.190.11 95 186 1.7E-23 T 06-07-2017 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Gene3D G3DSA:2.40.340.10 388 458 3.6E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 SUPERFAMILY SSF53218 232 378 1.57E-38 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 SUPERFAMILY SSF63867 383 457 5.36E-11 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 Pfam PF03454 MoeA C-terminal region (domain IV) 388 456 8.3E-9 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06565 fc7d0b55f5a629ef381ecf1bf1baa7bc 683 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 231 370 1.4E-29 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS25985 0faeb9e2825d2f23e764120ad9bcc05a 273 Pfam PF12697 Alpha/beta hydrolase family 64 264 5.1E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS25985 0faeb9e2825d2f23e764120ad9bcc05a 273 SUPERFAMILY SSF53474 83 271 2.76E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25985 0faeb9e2825d2f23e764120ad9bcc05a 273 Gene3D G3DSA:3.40.50.1820 84 270 2.6E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22905 92ab0ca3fb407c7c839c98f2bfad5df0 537 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 337 393 2.7E-6 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CAK95_RS22905 92ab0ca3fb407c7c839c98f2bfad5df0 537 Pfam PF00753 Metallo-beta-lactamase superfamily 14 241 3.2E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22905 92ab0ca3fb407c7c839c98f2bfad5df0 537 SUPERFAMILY SSF56281 14 406 1.6E-73 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22905 92ab0ca3fb407c7c839c98f2bfad5df0 537 SMART SM00849 2 200 4.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS22905 92ab0ca3fb407c7c839c98f2bfad5df0 537 Gene3D G3DSA:3.60.15.10 11 241 3.1E-60 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 SUPERFAMILY SSF52402 2 140 8.37E-28 T 06-07-2017 CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 PRINTS PR01438 Universal stress protein signature 118 140 6.2E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 PRINTS PR01438 Universal stress protein signature 101 113 6.2E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 PRINTS PR01438 Universal stress protein signature 2 20 6.2E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 Pfam PF00582 Universal stress protein family 1 140 1.9E-25 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS18100 96aba1abed1139cacdb77ce350be9f34 141 Gene3D G3DSA:3.40.50.620 2 140 1.5E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 Gene3D G3DSA:3.40.50.2300 65 184 3.8E-39 T 06-07-2017 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 Gene3D G3DSA:1.10.260.40 12 64 3.9E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 60 3.7E-9 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 SMART SM00354 11 83 1.5E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 SUPERFAMILY SSF47413 10 71 1.03E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 Gene3D G3DSA:3.40.50.2300 185 322 1.1E-45 T 06-07-2017 CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 SUPERFAMILY SSF53822 74 345 1.49E-73 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS16805 5cd5d63ec412af1dc447a9ed1d119c40 355 Pfam PF13377 Periplasmic binding protein-like domain 180 341 2.6E-37 T 06-07-2017 CAK95_RS21490 888fd18e8626f8a1135346c98ef7079c 304 Pfam PF02274 Amidinotransferase 11 279 4.2E-22 T 06-07-2017 CAK95_RS21490 888fd18e8626f8a1135346c98ef7079c 304 SUPERFAMILY SSF55909 8 281 9.38E-46 T 06-07-2017 CAK95_RS21490 888fd18e8626f8a1135346c98ef7079c 304 Gene3D G3DSA:3.75.10.10 8 281 5.1E-54 T 06-07-2017 CAK95_RS17675 69e140590ec735b18c0745b05fe4d7e4 237 Gene3D G3DSA:3.90.550.10 6 233 1.1E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17675 69e140590ec735b18c0745b05fe4d7e4 237 SUPERFAMILY SSF53448 6 234 6.57E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17675 69e140590ec735b18c0745b05fe4d7e4 237 Pfam PF02348 Cytidylyltransferase 9 133 2.3E-13 T 06-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 478 1.1E-133 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Pfam PF08245 Mur ligase middle domain 106 308 1.0E-45 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Gene3D G3DSA:3.40.1190.10 99 332 2.3E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Gene3D G3DSA:3.40.1390.10 16 96 1.3E-23 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 SUPERFAMILY SSF63418 1 96 3.92E-21 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 412 9.7E-22 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Pfam PF01225 Mur ligase family, catalytic domain 22 94 2.2E-10 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 SUPERFAMILY SSF53244 330 480 3.14E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 SUPERFAMILY SSF53623 97 328 1.26E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Gene3D G3DSA:3.90.190.20 333 471 1.3E-48 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14485 fc25d32fc30182bf8468291c6a6c4a59 493 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 478 30.71 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAK95_RS13510 0d07e3e573d1b9f42cca8359cc4837b1 365 SUPERFAMILY SSF53335 4 362 5.65E-107 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13510 0d07e3e573d1b9f42cca8359cc4837b1 365 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 63 297 5.6E-64 T 06-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 SUPERFAMILY SSF53597 141 353 1.35E-55 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 92 3.3E-15 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 351 1.6E-96 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 PIRSF PIRSF006769 1 357 1.9E-121 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 Gene3D G3DSA:3.40.430.10 120 352 3.4E-71 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 Gene3D G3DSA:3.40.140.10 1 119 9.7E-30 T 06-07-2017 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 351 4.2E-48 T 06-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 82 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 Pfam PF01872 RibD C-terminal domain 141 351 6.1E-44 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAK95_RS22440 f67b9c18bba78993f3c71cb3f480af76 357 SUPERFAMILY SSF53927 1 135 2.8E-44 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS01680 ddbeb3887a7f663b46d5ff6cb2072ee5 268 Gene3D G3DSA:2.40.440.10 22 137 7.9E-27 T 06-07-2017 CAK95_RS01680 ddbeb3887a7f663b46d5ff6cb2072ee5 268 SUPERFAMILY SSF141523 23 129 5.75E-29 T 06-07-2017 CAK95_RS01680 ddbeb3887a7f663b46d5ff6cb2072ee5 268 Pfam PF03734 L,D-transpeptidase catalytic domain 26 133 3.5E-20 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS06295 edfcdd05a7b3bc4dd8f225c4167988c3 349 SUPERFAMILY SSF53335 152 281 1.7E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06295 edfcdd05a7b3bc4dd8f225c4167988c3 349 Gene3D G3DSA:3.40.50.150 164 330 1.9E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06295 edfcdd05a7b3bc4dd8f225c4167988c3 349 Gene3D G3DSA:1.10.10.10 21 89 9.5E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06295 edfcdd05a7b3bc4dd8f225c4167988c3 349 SUPERFAMILY SSF46785 22 96 2.3E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06295 edfcdd05a7b3bc4dd8f225c4167988c3 349 Pfam PF13847 Methyltransferase domain 171 281 5.1E-22 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 SUPERFAMILY SSF55205 1 428 4.06E-132 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 Gene3D G3DSA:3.65.10.10 231 427 2.1E-59 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 426 2.7E-165 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 417 4.4E-91 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 Gene3D G3DSA:3.65.10.10 21 230 1.4E-64 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK95_RS05320 bf16c67621aa2bedefa4f773526b3fa8 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 427 44.035 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 Gene3D G3DSA:2.40.10.10 33 136 6.8E-29 T 06-07-2017 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 Gene3D G3DSA:2.30.42.10 246 340 6.7E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 Gene3D G3DSA:2.40.10.10 137 245 2.9E-39 T 06-07-2017 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 SUPERFAMILY SSF50494 39 241 5.35E-56 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 SMART SM00228 244 328 1.0E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 80 92 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 101 121 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 179 196 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 142 166 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 201 218 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 PRINTS PR00834 HtrA/DegQ protease family signature 286 298 3.7E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 Pfam PF13365 Trypsin-like peptidase domain 71 208 2.4E-34 T 06-07-2017 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 Pfam PF13180 PDZ domain 266 335 1.1E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS25205 19bc887922f584b21fd0e5aaa7a1dee9 351 SUPERFAMILY SSF50156 216 338 1.08E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 148 266 1.0E-18 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 Gene3D G3DSA:3.10.180.10 148 286 6.3E-45 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 244 265 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 Gene3D G3DSA:3.10.180.10 7 128 7.7E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 SUPERFAMILY SSF54593 6 309 9.77E-44 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28390 5609e88d8d2b08bb3ea389e9b03b33f3 327 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 13 307 4.8E-126 T 06-07-2017 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 PRINTS PR00502 NUDIX hydrolase family signature 53 68 7.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 PRINTS PR00502 NUDIX hydrolase family signature 39 53 7.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 SUPERFAMILY SSF55811 6 144 1.35E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 Pfam PF00293 NUDIX domain 14 128 1.5E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 Gene3D G3DSA:3.90.79.10 10 144 1.7E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS15720 a6cda556ab19ededb9fa314a913743a0 152 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS19875 42882f49177d21d942a9c50220705152 299 SUPERFAMILY SSF103481 44 145 9.81E-8 T 06-07-2017 CAK95_RS19875 42882f49177d21d942a9c50220705152 299 SUPERFAMILY SSF103481 195 284 7.19E-10 T 06-07-2017 CAK95_RS19875 42882f49177d21d942a9c50220705152 299 Pfam PF00892 EamA-like transporter family 10 141 1.1E-7 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS19875 42882f49177d21d942a9c50220705152 299 Pfam PF00892 EamA-like transporter family 151 278 6.1E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS06085 6a29921f5863785a3ca5e7a957c9e18a 208 Pfam PF02230 Phospholipase/Carboxylesterase 15 204 7.7E-11 T 06-07-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CAK95_RS06085 6a29921f5863785a3ca5e7a957c9e18a 208 SUPERFAMILY SSF53474 9 204 8.04E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06085 6a29921f5863785a3ca5e7a957c9e18a 208 Gene3D G3DSA:3.40.50.1820 3 206 6.8E-69 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS03845 2a894468a9e5f4f74a3261eca1473793 270 SUPERFAMILY SSF161098 6 256 1.59E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03845 2a894468a9e5f4f74a3261eca1473793 270 Gene3D G3DSA:1.10.3720.10 8 257 8.5E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03845 2a894468a9e5f4f74a3261eca1473793 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 253 2.1E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 Gene3D G3DSA:3.30.420.40 1 162 1.2E-40 T 06-07-2017 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 272 281 7.2E-43 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 322 2.1E-118 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 Pfam PF00814 Glycoprotease family 27 316 3.4E-91 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 315 3.0E-94 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 SUPERFAMILY SSF53067 108 318 3.33E-39 T 06-07-2017 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 340 61.458 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK95_RS08450 bf2e7ae384f6c6f4096a25b1b0598349 354 SUPERFAMILY SSF53067 3 127 3.37E-28 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Gene3D G3DSA:3.30.420.40 4 65 7.0E-24 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Gene3D G3DSA:3.30.420.40 98 181 7.0E-24 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Pfam PF06723 MreB/Mbl protein 137 222 5.9E-6 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Pfam PF00012 Hsp70 protein 292 387 9.5E-6 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 SUPERFAMILY SSF53067 172 240 1.3E-28 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 SUPERFAMILY SSF53067 290 412 1.3E-28 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 SUPERFAMILY SSF53067 4 166 6.47E-29 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Gene3D G3DSA:3.30.420.40 182 218 2.4E-13 T 06-07-2017 CAK95_RS25390 32477fa18249c9011e1a7756801aead8 420 Gene3D G3DSA:3.30.420.40 350 389 2.4E-13 T 06-07-2017 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 SUPERFAMILY SSF56645 19 216 1.57E-23 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 248 378 2.1E-21 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 Gene3D G3DSA:1.20.140.10 210 396 2.6E-37 T 06-07-2017 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 Gene3D G3DSA:2.40.110.10 123 209 1.1E-21 T 06-07-2017 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 SUPERFAMILY SSF47203 247 377 2.42E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 Gene3D G3DSA:1.10.540.10 6 121 3.5E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 PIRSF PIRSF016578 6 402 5.6E-107 T 06-07-2017 CAK95_RS01195 eea64a1a3cf46cb3a94735b21258a5c9 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 29 100 1.1E-4 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 144 157 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 206 221 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 SMART SM00448 1 110 0.0071 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 333 342 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Pfam PF02954 Bacterial regulatory protein, Fis family 397 437 8.3E-15 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Gene3D G3DSA:1.10.10.60 347 437 1.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 SUPERFAMILY SSF52172 4 164 5.13E-14 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Gene3D G3DSA:1.10.8.60 293 346 1.7E-19 T 06-07-2017 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 403 420 6.1E-7 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 440 6.1E-7 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Pfam PF00158 Sigma-54 interaction domain 122 286 2.6E-67 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Gene3D G3DSA:3.40.50.2300 2 118 2.0E-9 T 06-07-2017 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 SUPERFAMILY SSF52540 120 361 9.54E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15330 0d29596e85005c216208154a5081d916 456 SMART SM00382 140 283 2.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15330 0d29596e85005c216208154a5081d916 456 SUPERFAMILY SSF46689 363 437 5.38E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Pfam PF00072 Response regulator receiver domain 11 107 3.7E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15330 0d29596e85005c216208154a5081d916 456 Gene3D G3DSA:3.40.50.300 119 292 3.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 Gene3D G3DSA:3.40.50.720 1 163 1.0E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 SUPERFAMILY SSF48179 186 358 3.74E-44 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 101 9.3E-7 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 184 329 1.2E-26 T 06-07-2017 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 Gene3D G3DSA:1.10.1040.10 194 347 2.9E-39 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS27075 013a7b7af77d801318d64ef13df2688e 362 SUPERFAMILY SSF51735 1 173 4.42E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 Hamap MF_00577 Urocanate hydratase [hutU]. 2 553 50.08 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 ProSitePatterns PS01233 Urocanase signature. 441 456 - T 06-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 PIRSF PIRSF001423 2 554 1.1E-292 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 Gene3D G3DSA:3.40.50.10730 141 348 3.8E-95 T 06-07-2017 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 Pfam PF01175 Urocanase 11 546 7.3E-263 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 TIGRFAM TIGR01228 hutU: urocanate hydratase 10 552 4.3E-290 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 SUPERFAMILY SSF111326 5 553 1.1E-261 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 Gene3D G3DSA:3.40.1770.10 359 553 3.5E-160 T 06-07-2017 CAK95_RS06105 ea7009dfa593a903aed592ee347844b7 554 Gene3D G3DSA:3.40.1770.10 9 140 3.5E-160 T 06-07-2017 CAK95_RS28615 97702625f9333d314fef661563ff9ecf 364 Pfam PF02653 Branched-chain amino acid transport system / permease component 78 349 2.4E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS08385 5b8058ec72eaf02f2e44b5026f5ccde4 555 SMART SM01079 84 263 1.7E-7 T 06-07-2017 IPR006189 CHASE domain CAK95_RS08385 5b8058ec72eaf02f2e44b5026f5ccde4 555 SMART SM00911 356 434 7.8E-25 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS08385 5b8058ec72eaf02f2e44b5026f5ccde4 555 Pfam PF03924 CHASE domain 100 251 2.9E-17 T 06-07-2017 IPR006189 CHASE domain CAK95_RS08385 5b8058ec72eaf02f2e44b5026f5ccde4 555 Pfam PF07536 HWE histidine kinase 356 434 1.4E-18 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.0E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 SUPERFAMILY SSF53850 88 294 2.17E-40 T 06-07-2017 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 Gene3D G3DSA:1.10.10.10 1 84 7.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 SUPERFAMILY SSF46785 1 86 4.36E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 Gene3D G3DSA:3.40.190.10 175 264 1.3E-38 T 06-07-2017 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 Gene3D G3DSA:3.40.190.10 88 174 1.3E-30 T 06-07-2017 CAK95_RS26250 1f4978a1a83fb3bd27d492b37ab90e7f 318 Pfam PF03466 LysR substrate binding domain 87 291 1.3E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 234 251 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 277 295 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 50 68 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 69 88 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 185 202 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 256 274 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 25 46 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00691 Adhesin B signature 127 146 3.5E-32 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 Gene3D G3DSA:3.40.50.1980 178 299 1.1E-46 T 06-07-2017 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 Gene3D G3DSA:3.40.50.1980 18 177 1.9E-57 T 06-07-2017 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 56 69 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 69 86 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 185 206 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 264 283 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 25 43 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 PRINTS PR00690 Adhesin family signature 238 256 6.9E-31 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 SUPERFAMILY SSF53807 19 299 1.13E-91 T 06-07-2017 CAK95_RS12890 926f70dcb47479facd65acf31e4b978f 300 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 296 4.4E-88 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAK95_RS08815 ca1a71d0ee2740db7c0b1e08daf01864 309 SUPERFAMILY SSF55729 53 275 4.24E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08815 ca1a71d0ee2740db7c0b1e08daf01864 309 Pfam PF13444 Acetyltransferase (GNAT) domain 70 180 3.1E-31 T 06-07-2017 CAK95_RS08815 ca1a71d0ee2740db7c0b1e08daf01864 309 Gene3D G3DSA:3.40.630.30 55 200 5.6E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 Gene3D G3DSA:3.20.20.140 72 418 4.1E-119 T 06-07-2017 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 ProSitePatterns PS00482 Dihydroorotase signature 1. 61 69 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 TIGRFAM TIGR03178 allantoinase: allantoinase 6 443 5.7E-116 T 06-07-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 ProSitePatterns PS00483 Dihydroorotase signature 2. 311 322 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 Gene3D G3DSA:2.30.40.10 6 71 2.1E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 Pfam PF01979 Amidohydrolase family 55 431 1.8E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 434 9.0E-103 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 SUPERFAMILY SSF51338 5 57 5.05E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 SUPERFAMILY SSF51338 377 439 5.05E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS07915 047b05b6ba46e988f00b5655e63e76cf 480 SUPERFAMILY SSF51556 58 377 1.99E-106 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS17305 f318d67b515dc6a20c8d1bab0da6ad2e 250 Gene3D G3DSA:3.40.50.300 7 247 1.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17305 f318d67b515dc6a20c8d1bab0da6ad2e 250 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 9 250 2.6E-113 T 06-07-2017 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CAK95_RS17305 f318d67b515dc6a20c8d1bab0da6ad2e 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 249 2.5E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS17305 f318d67b515dc6a20c8d1bab0da6ad2e 250 SUPERFAMILY SSF52540 9 248 1.78E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17305 f318d67b515dc6a20c8d1bab0da6ad2e 250 Pfam PF00005 ABC transporter 25 180 2.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 SUPERFAMILY SSF52922 337 472 4.58E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Gene3D G3DSA:2.40.50.100 1 89 1.3E-32 T 06-07-2017 CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Gene3D G3DSA:3.40.50.920 344 472 1.7E-47 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 SUPERFAMILY SSF52518 153 342 7.85E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Pfam PF02779 Transketolase, pyrimidine binding domain 154 328 2.1E-49 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Pfam PF00364 Biotin-requiring enzyme 4 77 5.8E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Gene3D G3DSA:3.40.50.970 152 343 9.2E-93 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 SMART SM00861 153 328 3.3E-61 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 SUPERFAMILY SSF51230 1 88 2.22E-27 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS23170 d637f577736e832e28811474aaaa81a5 475 Pfam PF02780 Transketolase, C-terminal domain 343 465 1.0E-42 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK95_RS27380 08bd3b4f9e5e965cbfc7691b4030a7cf 243 SUPERFAMILY SSF54909 128 225 3.22E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS27380 08bd3b4f9e5e965cbfc7691b4030a7cf 243 Gene3D G3DSA:3.30.70.900 128 219 5.7E-17 T 06-07-2017 CAK95_RS27380 08bd3b4f9e5e965cbfc7691b4030a7cf 243 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 130 217 1.5E-9 T 06-07-2017 IPR009799 EthD domain CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 193 198 - T 06-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 SUPERFAMILY SSF47781 35 103 4.82E-6 T 06-07-2017 IPR010994 RuvA domain 2-like CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 Pfam PF04002 RadC-like JAB domain 124 240 1.1E-44 T 06-07-2017 IPR025657 RadC-like JAB domain CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 TIGRFAM TIGR00608 radc: DNA repair protein RadC 31 239 2.2E-70 T 06-07-2017 IPR001405 RadC protein CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 Gene3D G3DSA:3.40.140.10 120 240 3.4E-49 T 06-07-2017 CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 SUPERFAMILY SSF102712 169 214 3.66E-6 T 06-07-2017 CAK95_RS08265 d8d0df2046c0bd7718bfc47542e2e806 244 Gene3D G3DSA:1.10.150.20 66 103 1.4E-4 T 06-07-2017 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Gene3D G3DSA:1.10.287.130 340 394 3.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Pfam PF00512 His Kinase A (phospho-acceptor) domain 346 407 2.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 SUPERFAMILY SSF55874 398 577 2.75E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 SMART SM00304 287 342 1.0E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 SMART SM00388 343 408 6.2E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 SUPERFAMILY SSF47384 328 407 1.9E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Pfam PF00672 HAMP domain 270 335 2.0E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 SMART SM00387 457 578 2.7E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 576 1.5E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Pfam PF13755 Sensor N-terminal transmembrane domain 26 94 4.8E-26 T 06-07-2017 IPR025908 Sensor N-terminal transmembrane domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Pfam PF13756 Stimulus-sensing domain 119 227 9.7E-38 T 06-07-2017 IPR025919 Stimulus-sensing domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 Gene3D G3DSA:3.30.565.10 395 577 1.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 522 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS06845 3390551628eb75dfc6eb61df3a48b478 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 546 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 SMART SM00382 449 622 2.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 SUPERFAMILY SSF52540 419 618 3.29E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 Gene3D G3DSA:1.20.1560.10 80 396 1.7E-14 T 06-07-2017 CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 Pfam PF00005 ABC transporter 441 575 1.5E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 Gene3D G3DSA:3.40.50.300 423 610 3.6E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 ProSitePatterns PS00211 ABC transporters family signature. 547 561 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 SUPERFAMILY SSF90123 79 396 1.44E-23 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS25025 358491e9461cae4c80367041c381d5af 656 Pfam PF06472 ABC transporter transmembrane region 2 81 348 1.3E-42 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 Pfam PF01019 Gamma-glutamyltranspeptidase 27 525 5.5E-118 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 368 386 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 224 240 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 33 58 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 344 362 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 272 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 399 414 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 126 145 3.1E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12960 4c486f0f09583bbdd5dbf6beb8123bc2 531 SUPERFAMILY SSF56235 6 529 7.91E-139 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 535 2.0E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Pfam PF00501 AMP-binding enzyme 37 449 1.4E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Gene3D G3DSA:3.40.50.980 207 368 1.7E-32 T 06-07-2017 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Gene3D G3DSA:3.30.300.30 443 545 1.8E-22 T 06-07-2017 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 24 542 1.0E-230 T 06-07-2017 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Gene3D G3DSA:3.40.50.980 37 206 7.0E-39 T 06-07-2017 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 SUPERFAMILY SSF56801 20 544 6.93E-141 T 06-07-2017 CAK95_RS09645 18a28d9dfd600b13a65b0de55bc82000 548 Gene3D G3DSA:2.30.38.10 369 438 1.4E-20 T 06-07-2017 CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 SUPERFAMILY SSF50129 1 160 2.67E-40 T 06-07-2017 IPR011032 GroES-like CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 Gene3D G3DSA:3.90.180.10 1 160 5.3E-48 T 06-07-2017 IPR011032 GroES-like CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 SMART SM00829 10 333 2.6E-36 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 SUPERFAMILY SSF51735 131 308 1.15E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 122 6.3E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 Pfam PF00107 Zinc-binding dehydrogenase 167 297 4.0E-29 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS19295 ca4a13b957ad16c54fc0c4dbb76d8160 335 Gene3D G3DSA:3.40.50.720 161 282 4.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Pfam PF12848 ABC transporter 229 309 1.3E-26 T 06-07-2017 IPR032781 ABC-transporter extension domain CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Gene3D G3DSA:3.40.50.300 1 88 1.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Gene3D G3DSA:3.40.50.300 323 532 5.4E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Gene3D G3DSA:3.40.50.300 123 277 1.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Pfam PF00005 ABC transporter 21 190 2.5E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 Pfam PF00005 ABC transporter 341 471 1.7E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 SUPERFAMILY SSF52540 304 524 2.99E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 SUPERFAMILY SSF52540 131 255 2.56E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 SUPERFAMILY SSF52540 2 92 2.56E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 SMART SM00382 26 235 2.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09310 a43bf458da01137fb0e1a12941af92f9 540 SMART SM00382 349 516 2.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10955 e40df50117d3f6e9302818e1a6cb02c4 333 Gene3D G3DSA:3.30.1780.10 1 155 2.3E-45 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAK95_RS10955 e40df50117d3f6e9302818e1a6cb02c4 333 PIRSF PIRSF001439 1 332 7.6E-73 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS10955 e40df50117d3f6e9302818e1a6cb02c4 333 Gene3D G3DSA:3.40.50.720 156 315 5.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10955 e40df50117d3f6e9302818e1a6cb02c4 333 SUPERFAMILY SSF51735 1 329 1.22E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10955 e40df50117d3f6e9302818e1a6cb02c4 333 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 79 329 2.5E-64 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 Gene3D G3DSA:1.10.10.10 5 72 2.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 SUPERFAMILY SSF46785 5 76 6.67E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 Pfam PF07729 FCD domain 82 206 1.1E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 6.0E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 SUPERFAMILY SSF48008 78 210 2.28E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 SMART SM00345 14 72 1.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 SMART SM00895 82 206 1.4E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27710 7bdc3b82a7867d3f1bee202f87985a2d 218 Gene3D G3DSA:1.20.120.530 76 217 9.9E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS10685 bc3f1db5cdc1ae75f683c06f1d2cdc85 198 SMART SM00347 68 168 8.6E-4 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10685 bc3f1db5cdc1ae75f683c06f1d2cdc85 198 SUPERFAMILY SSF46785 64 183 6.43E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10685 bc3f1db5cdc1ae75f683c06f1d2cdc85 198 Pfam PF12802 MarR family 71 132 1.4E-6 T 06-07-2017 CAK95_RS10685 bc3f1db5cdc1ae75f683c06f1d2cdc85 198 Gene3D G3DSA:1.10.10.10 74 181 1.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02585 843ed8c57f07ba008cdaad313e9ace95 88 SUPERFAMILY SSF47413 14 84 2.51E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02585 843ed8c57f07ba008cdaad313e9ace95 88 SMART SM00530 27 83 1.2E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS02585 843ed8c57f07ba008cdaad313e9ace95 88 Gene3D G3DSA:1.10.260.40 13 77 3.1E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02585 843ed8c57f07ba008cdaad313e9ace95 88 Pfam PF13744 Helix-turn-helix domain 5 78 1.3E-19 T 06-07-2017 CAK95_RS02490 1019b43a718bc59bdb2a4eddb4ea76c6 181 Pfam PF10502 Signal peptidase, peptidase S26 29 166 6.3E-50 T 06-07-2017 IPR019533 Peptidase S26 CAK95_RS02490 1019b43a718bc59bdb2a4eddb4ea76c6 181 SUPERFAMILY SSF51306 31 178 1.78E-25 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS02490 1019b43a718bc59bdb2a4eddb4ea76c6 181 Gene3D G3DSA:2.10.109.10 128 174 2.1E-11 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS02490 1019b43a718bc59bdb2a4eddb4ea76c6 181 Gene3D G3DSA:2.10.109.10 34 90 2.1E-11 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS09725 fadcf787d80e9976586470d62790dc77 271 Gene3D G3DSA:3.40.50.1820 10 256 6.8E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09725 fadcf787d80e9976586470d62790dc77 271 SUPERFAMILY SSF53474 11 256 9.7E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09725 fadcf787d80e9976586470d62790dc77 271 Pfam PF00561 alpha/beta hydrolase fold 30 145 2.3E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 162 3.2E-55 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 PRINTS PR01576 Peptide deformylase signature 33 62 4.9E-38 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 PRINTS PR01576 Peptide deformylase signature 104 122 4.9E-38 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 PRINTS PR01576 Peptide deformylase signature 123 152 4.9E-38 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 PRINTS PR01576 Peptide deformylase signature 92 103 4.9E-38 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 SUPERFAMILY SSF56420 2 167 9.16E-64 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 Pfam PF01327 Polypeptide deformylase 4 155 1.5E-54 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 Hamap MF_00163 Peptide deformylase [def]. 2 165 30.817 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 Gene3D G3DSA:3.90.45.10 5 168 1.2E-66 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS02845 397dd3ab8e97aa2d272a2f3631b876c3 171 PIRSF PIRSF004749 1 171 2.6E-57 T 06-07-2017 IPR023635 Peptide deformylase CAK95_RS08745 177e922192078bbaba7856fa5bcd0cfb 417 Gene3D G3DSA:3.40.50.720 5 195 1.8E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08745 177e922192078bbaba7856fa5bcd0cfb 417 SUPERFAMILY SSF51905 4 149 3.63E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08745 177e922192078bbaba7856fa5bcd0cfb 417 SUPERFAMILY SSF51905 282 357 3.63E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08745 177e922192078bbaba7856fa5bcd0cfb 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 9.3E-7 T 06-07-2017 CAK95_RS08745 177e922192078bbaba7856fa5bcd0cfb 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 9.3E-7 T 06-07-2017 CAK95_RS15575 dde0691cf86acde8249632ea8855e0fc 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 7.4E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15575 dde0691cf86acde8249632ea8855e0fc 328 SUPERFAMILY SSF53850 117 288 1.41E-10 T 06-07-2017 CAK95_RS15575 dde0691cf86acde8249632ea8855e0fc 328 PIRSF PIRSF017082 2 327 8.7E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS04890 3718a7598bda684d440439f6644e6b19 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 264 2.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04890 3718a7598bda684d440439f6644e6b19 276 Gene3D G3DSA:1.10.3720.10 79 261 1.8E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04890 3718a7598bda684d440439f6644e6b19 276 SUPERFAMILY SSF161098 78 259 1.7E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24760 f06a0132a1992cf563eafc37a3aeef95 611 Pfam PF01368 DHH family 107 208 4.7E-11 T 06-07-2017 IPR001667 DDH domain CAK95_RS24760 f06a0132a1992cf563eafc37a3aeef95 611 SUPERFAMILY SSF64182 81 484 7.59E-111 T 06-07-2017 CAK95_RS24760 f06a0132a1992cf563eafc37a3aeef95 611 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 53 601 1.9E-156 T 06-07-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CAK95_RS24760 f06a0132a1992cf563eafc37a3aeef95 611 Pfam PF02272 DHHA1 domain 411 476 9.0E-11 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 248 3.4E-50 T 06-07-2017 CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 SUPERFAMILY SSF51735 3 249 4.44E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 192 0.0024 T 06-07-2017 CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 Gene3D G3DSA:3.40.50.720 3 249 1.2E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 9.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27620 6482babcfc00a3c372ac7089a88d8b6a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 9.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 Pfam PF01494 FAD binding domain 5 349 8.1E-28 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 Gene3D G3DSA:3.50.50.60 275 358 9.9E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 Gene3D G3DSA:3.50.50.60 3 179 9.9E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 SUPERFAMILY SSF51905 275 363 6.76E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 SUPERFAMILY SSF51905 4 174 6.76E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 9.3E-16 T 06-07-2017 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 9.3E-16 T 06-07-2017 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 9.3E-16 T 06-07-2017 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 9.3E-16 T 06-07-2017 CAK95_RS07105 2c959d0c30d13f20795a186d64cb79a5 394 SUPERFAMILY SSF54373 179 275 1.79E-15 T 06-07-2017 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 317 557 1.1E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 613 677 5.3E-13 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 51 194 6.5E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Gene3D G3DSA:3.30.365.10 556 722 7.4E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Gene3D G3DSA:3.30.365.10 392 555 2.5E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 SMART SM01008 218 296 7.7E-13 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 SUPERFAMILY SSF56003 319 722 6.15E-107 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Gene3D G3DSA:3.90.1170.50 184 266 3.5E-17 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 Gene3D G3DSA:3.30.365.10 51 183 9.0E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 PIRSF PIRSF036389 1 727 9.0E-239 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAK95_RS21190 2557aee81ee223513b678ef45c74bae2 727 SUPERFAMILY SSF56003 48 251 3.0E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01410 87040fa66d6e02c8933800423b655af2 528 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 35 413 7.5E-95 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS01410 87040fa66d6e02c8933800423b655af2 528 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 19 439 5.0E-88 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS01410 87040fa66d6e02c8933800423b655af2 528 Gene3D G3DSA:3.40.1670.10 327 438 2.3E-26 T 06-07-2017 CAK95_RS01410 87040fa66d6e02c8933800423b655af2 528 SUPERFAMILY SSF143968 315 447 1.09E-32 T 06-07-2017 CAK95_RS01410 87040fa66d6e02c8933800423b655af2 528 SUPERFAMILY SSF50475 19 302 1.18E-71 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 ProSitePatterns PS00056 Ribosomal protein S17 signature. 54 66 - T 06-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 1 79 22.885 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 SUPERFAMILY SSF50249 3 79 1.63E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 1.1E-8 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 1.1E-8 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 1.1E-8 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 Gene3D G3DSA:2.40.50.140 1 79 5.8E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 Pfam PF00366 Ribosomal protein S17 8 74 2.9E-28 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 73 2.0E-27 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21310 6b83b79acd733c89209031a24836f208 83 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 9.5E-33 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS28060 f23456d39370f31b82e62499209edcfa 101 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 13 98 2.2E-34 T 06-07-2017 IPR014543 Uncharacterised conserved protein UCP028291 CAK95_RS28060 f23456d39370f31b82e62499209edcfa 101 PIRSF PIRSF028291 1 101 1.1E-32 T 06-07-2017 IPR014543 Uncharacterised conserved protein UCP028291 CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 Gene3D G3DSA:3.10.129.10 1 143 2.1E-44 T 06-07-2017 IPR029069 HotDog domain CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 SUPERFAMILY SSF54637 10 155 2.7E-38 T 06-07-2017 IPR029069 HotDog domain CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 Pfam PF13452 N-terminal half of MaoC dehydratase 48 137 2.0E-10 T 06-07-2017 CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 SUPERFAMILY SSF54637 162 275 1.82E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 Pfam PF01575 MaoC like domain 163 274 9.5E-25 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS10215 3522e38275bfc5185ea7df56e12a1ddf 284 Gene3D G3DSA:3.10.129.10 144 277 6.7E-38 T 06-07-2017 IPR029069 HotDog domain CAK95_RS03910 135cf9d83ae3df6663994543e6d1993d 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 10 99 1.4E-16 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD CAK95_RS18280 993d7b1d35a2214d4073f8c2865268e2 136 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 71 132 3.2E-12 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAK95_RS18280 993d7b1d35a2214d4073f8c2865268e2 136 Pfam PF00460 Flagella basal body rod protein 9 34 9.2E-6 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAK95_RS18280 993d7b1d35a2214d4073f8c2865268e2 136 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 135 9.5E-42 T 06-07-2017 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 Pfam PF14579 Helix-hairpin-helix motif 806 892 1.4E-24 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 Gene3D G3DSA:1.10.150.280 831 879 1.0E-6 T 06-07-2017 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 SUPERFAMILY SSF89550 6 271 5.23E-10 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 Gene3D G3DSA:3.20.20.140 6 267 1.3E-16 T 06-07-2017 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 SMART SM00481 7 74 1.2E-20 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1025 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 Pfam PF02811 PHP domain 8 182 1.1E-31 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 302 732 1.2E-173 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS22950 6a4c37c486ed3cddacc2cc1154bdbf0c 1143 SUPERFAMILY SSF160975 827 879 1.83E-7 T 06-07-2017 CAK95_RS17965 e286abe3b351f5924f4398f32bbb618a 324 Gene3D G3DSA:3.40.50.1100 72 321 8.7E-66 T 06-07-2017 CAK95_RS17965 e286abe3b351f5924f4398f32bbb618a 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 310 3.5E-76 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS17965 e286abe3b351f5924f4398f32bbb618a 324 SUPERFAMILY SSF53686 5 320 1.31E-91 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS22235 6dd40e52760caaed77631297da9aa268 163 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 36.179 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK95_RS22235 6dd40e52760caaed77631297da9aa268 163 SUPERFAMILY SSF50249 4 163 4.11E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22235 6dd40e52760caaed77631297da9aa268 163 Pfam PF00436 Single-strand binding protein family 5 105 1.6E-39 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAK95_RS22235 6dd40e52760caaed77631297da9aa268 163 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 163 2.4E-45 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK95_RS22235 6dd40e52760caaed77631297da9aa268 163 Gene3D G3DSA:2.40.50.140 2 163 2.2E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS01945 31f0ba7d94567af1d18ca5a6f12912b2 141 SMART SM00422 4 72 5.2E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS01945 31f0ba7d94567af1d18ca5a6f12912b2 141 Gene3D G3DSA:1.10.1660.10 58 123 7.8E-11 T 06-07-2017 CAK95_RS01945 31f0ba7d94567af1d18ca5a6f12912b2 141 Gene3D G3DSA:1.10.1660.10 3 57 2.3E-16 T 06-07-2017 CAK95_RS01945 31f0ba7d94567af1d18ca5a6f12912b2 141 SUPERFAMILY SSF46955 4 123 6.59E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS01945 31f0ba7d94567af1d18ca5a6f12912b2 141 Pfam PF13411 MerR HTH family regulatory protein 4 69 1.0E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 163 184 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 366 385 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 268 294 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 58 74 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 418 435 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 139 163 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PRINTS PR01806 Virulence factor MviN signature 39 58 8.4E-55 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 Pfam PF03023 MviN-like protein 34 472 7.6E-90 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 9 511 6.8E-105 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS09260 ae1245c815e6b68e5382b49d5594d96f 524 PIRSF PIRSF002869 5 523 2.9E-119 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 471 500 2.1E-21 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 423 452 2.1E-21 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 421 2.1E-21 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 3 28 2.1E-21 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 SUPERFAMILY SSF58104 302 549 1.11E-55 T 06-07-2017 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 SUPERFAMILY SSF58104 236 262 1.11E-55 T 06-07-2017 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 SMART SM00283 285 550 3.1E-36 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 371 549 3.7E-36 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 Gene3D G3DSA:1.10.287.950 313 518 2.5E-45 T 06-07-2017 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 SMART SM00304 207 260 4.3E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS08845 3dda0cedfb13d00de0bafc9cc62e29ed 556 Pfam PF00672 HAMP domain 188 256 5.8E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS02295 93420249a6de74eabe121420c1769c01 498 Gene3D G3DSA:3.40.309.10 276 455 2.0E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS02295 93420249a6de74eabe121420c1769c01 498 Gene3D G3DSA:3.40.605.10 21 275 2.3E-85 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS02295 93420249a6de74eabe121420c1769c01 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS02295 93420249a6de74eabe121420c1769c01 498 SUPERFAMILY SSF53720 17 493 2.23E-154 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS02295 93420249a6de74eabe121420c1769c01 498 Pfam PF00171 Aldehyde dehydrogenase family 29 490 2.9E-151 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 80 1.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 SUPERFAMILY SSF48008 111 237 1.46E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 Gene3D G3DSA:1.10.10.10 21 90 1.8E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 3.5E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 3.5E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 Pfam PF07729 FCD domain 113 230 1.3E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 SUPERFAMILY SSF46785 14 84 1.96E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 SMART SM00345 21 80 4.9E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 Gene3D G3DSA:1.20.120.530 108 239 1.5E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS11400 6adddd421d9a41b22711922938f7fba8 260 SMART SM00895 110 232 1.6E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS25325 bad5bb751458e0720c305cfa0e50dd64 378 Pfam PF07690 Major Facilitator Superfamily 5 228 2.4E-17 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS25325 bad5bb751458e0720c305cfa0e50dd64 378 Gene3D G3DSA:1.20.1250.20 3 176 7.4E-20 T 06-07-2017 CAK95_RS25325 bad5bb751458e0720c305cfa0e50dd64 378 Gene3D G3DSA:1.20.1250.20 197 368 1.7E-24 T 06-07-2017 CAK95_RS25325 bad5bb751458e0720c305cfa0e50dd64 378 SUPERFAMILY SSF103473 6 370 3.92E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS25325 bad5bb751458e0720c305cfa0e50dd64 378 ProSitePatterns PS00216 Sugar transport proteins signature 1. 248 264 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK95_RS10195 c8dcd59d8931e0639a478b06957dd665 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 253 3.2E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10195 c8dcd59d8931e0639a478b06957dd665 257 SUPERFAMILY SSF161098 63 244 1.7E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10195 c8dcd59d8931e0639a478b06957dd665 257 Gene3D G3DSA:1.10.3720.10 62 251 2.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27265 6af4059a38d822e72f5f4cb9b93d3700 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 291 2.0E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Gene3D G3DSA:3.10.50.40 162 224 2.2E-10 T 06-07-2017 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 PIRSF PIRSF003095 1 449 9.7E-121 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 TIGRFAM TIGR00115 tig: trigger factor 11 427 4.5E-126 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 167 245 2.1E-13 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 270 427 8.2E-42 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 SUPERFAMILY SSF54534 110 246 1.73E-29 T 06-07-2017 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Pfam PF05697 Bacterial trigger factor protein (TF) 1 151 9.4E-33 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 SUPERFAMILY SSF102735 1 137 5.49E-29 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Gene3D G3DSA:1.10.3120.10 225 401 1.9E-52 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Gene3D G3DSA:3.30.70.1050 1 125 1.3E-27 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 Hamap MF_00303 Trigger factor [tig]. 1 433 20.127 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK95_RS22700 8233308db5ab90a489d27cfa6ac8d0e3 451 SUPERFAMILY SSF109998 258 443 2.09E-47 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 Gene3D G3DSA:3.40.50.1000 87 241 1.5E-36 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 3 194 7.3E-65 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 87 191 3.7E-15 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 SUPERFAMILY SSF56784 2 243 1.62E-52 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 Gene3D G3DSA:1.10.150.240 18 86 3.5E-28 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 5 184 8.0E-34 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 43 56 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 29 42 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS21075 d5fc2e0ca9147bb4dbcdb3d20779ca51 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 193 2.2E-40 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 SUPERFAMILY SSF46785 6 112 5.27E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 SUPERFAMILY SSF53850 95 300 8.69E-41 T 06-07-2017 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 Gene3D G3DSA:3.40.190.10 179 265 3.1E-17 T 06-07-2017 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 Pfam PF03466 LysR substrate binding domain 92 296 8.0E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 Gene3D G3DSA:1.10.10.10 7 91 2.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.3E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07630 d7e9d3a0125be701d8f1c73ed1f3d08b 308 Gene3D G3DSA:3.40.190.10 94 178 3.0E-6 T 06-07-2017 CAK95_RS18115 5afc0260cbdb63c2f7cb6d67fece1a3c 283 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 31 177 5.6E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS18115 5afc0260cbdb63c2f7cb6d67fece1a3c 283 SUPERFAMILY SSF52540 11 239 8.2E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18115 5afc0260cbdb63c2f7cb6d67fece1a3c 283 Gene3D G3DSA:3.40.50.300 14 203 2.1E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18115 5afc0260cbdb63c2f7cb6d67fece1a3c 283 SMART SM00382 27 185 5.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 166 187 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 Gene3D G3DSA:3.40.190.10 137 197 8.4E-23 T 06-07-2017 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 4 310 25.566 T 06-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 SUPERFAMILY SSF53850 5 231 3.04E-48 T 06-07-2017 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 Gene3D G3DSA:3.40.190.10 5 136 2.2E-25 T 06-07-2017 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 209 5.9E-53 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK95_RS13240 e006edd1bdf48dffa7eca0be49b6db1e 323 Pfam PF01634 ATP phosphoribosyltransferase 56 231 2.1E-37 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Gene3D G3DSA:1.10.8.60 313 388 2.3E-20 T 06-07-2017 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Gene3D G3DSA:3.40.50.2300 5 146 3.7E-32 T 06-07-2017 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 SUPERFAMILY SSF52172 4 184 1.57E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 SUPERFAMILY SSF52540 140 380 6.27E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 SMART SM00382 160 307 1.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Gene3D G3DSA:1.10.10.60 404 472 6.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 453 473 3.2E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 453 3.2E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Gene3D G3DSA:3.40.50.300 147 312 1.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Pfam PF00072 Response regulator receiver domain 6 113 1.9E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 470 5.6E-218 T 06-07-2017 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 SMART SM00448 4 115 7.1E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 SUPERFAMILY SSF46689 406 472 4.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Pfam PF02954 Bacterial regulatory protein, Fis family 430 468 2.2E-13 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS23255 4d84766d23527d3831c992f6664c7b45 479 Pfam PF00158 Sigma-54 interaction domain 140 306 3.6E-69 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAK95_RS14550 f3b2cb11e14a0d879a63541de43c1c1e 1244 Pfam PF05170 AsmA family 30 177 1.7E-13 T 06-07-2017 IPR007844 AsmA CAK95_RS14550 f3b2cb11e14a0d879a63541de43c1c1e 1244 Pfam PF13502 AsmA-like C-terminal region 885 1079 3.5E-16 T 06-07-2017 IPR032712 AsmA-like, C-terminal CAK95_RS22670 09eccc3cb7eb598f42eec1bbcf954568 367 SUPERFAMILY SSF53850 151 326 3.77E-14 T 06-07-2017 CAK95_RS22670 09eccc3cb7eb598f42eec1bbcf954568 367 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 88 363 1.7E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS22670 09eccc3cb7eb598f42eec1bbcf954568 367 PIRSF PIRSF017082 39 367 2.7E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17220 2bba3d05239a393feb4e9ca94bdb1852 318 Pfam PF09084 NMT1/THI5 like 46 249 3.1E-19 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS17220 2bba3d05239a393feb4e9ca94bdb1852 318 SUPERFAMILY SSF53850 29 250 4.59E-29 T 06-07-2017 CAK95_RS17220 2bba3d05239a393feb4e9ca94bdb1852 318 Gene3D G3DSA:3.40.190.10 112 236 3.5E-12 T 06-07-2017 CAK95_RS07195 1e7a432352519d5deca720bfa61362fa 338 PIRSF PIRSF017082 3 338 2.3E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07195 1e7a432352519d5deca720bfa61362fa 338 SUPERFAMILY SSF53850 127 301 2.34E-12 T 06-07-2017 CAK95_RS07195 1e7a432352519d5deca720bfa61362fa 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 332 5.0E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS22790 96b017076d7d1b0c329b6a898d751a3b 345 Pfam PF07728 AAA domain (dynein-related subfamily) 31 154 1.6E-6 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAK95_RS22790 96b017076d7d1b0c329b6a898d751a3b 345 Gene3D G3DSA:3.40.50.300 19 163 6.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22790 96b017076d7d1b0c329b6a898d751a3b 345 SUPERFAMILY SSF52540 12 176 1.76E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04920 d355009efbb44cd52805e84216555501 277 SMART SM01092 175 275 0.0035 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS04920 d355009efbb44cd52805e84216555501 277 Gene3D G3DSA:3.30.43.10 13 52 8.9E-7 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS04920 d355009efbb44cd52805e84216555501 277 Gene3D G3DSA:3.30.465.10 65 160 3.2E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS04920 d355009efbb44cd52805e84216555501 277 SUPERFAMILY SSF56176 13 174 4.03E-36 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS04920 d355009efbb44cd52805e84216555501 277 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 14 161 3.7E-34 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS04920 d355009efbb44cd52805e84216555501 277 Gene3D G3DSA:3.30.390.50 189 274 1.1E-7 T 06-07-2017 CAK95_RS04920 d355009efbb44cd52805e84216555501 277 SUPERFAMILY SSF55447 187 274 1.57E-8 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS25675 b2cccaf9632359c45c911a950bdded8a 159 Pfam PF02675 S-adenosylmethionine decarboxylase 52 156 8.7E-36 T 06-07-2017 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CAK95_RS25675 b2cccaf9632359c45c911a950bdded8a 159 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 48 156 8.0E-39 T 06-07-2017 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CAK95_RS25675 b2cccaf9632359c45c911a950bdded8a 159 Gene3D G3DSA:3.60.90.10 37 157 8.2E-42 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CAK95_RS25675 b2cccaf9632359c45c911a950bdded8a 159 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 46 157 25.56 T 06-07-2017 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CAK95_RS25675 b2cccaf9632359c45c911a950bdded8a 159 SUPERFAMILY SSF56276 49 157 9.02E-33 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CAK95_RS25020 6cab84b6320234e27ffba034243403f8 159 Gene3D G3DSA:2.60.120.10 13 149 3.9E-27 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS25020 6cab84b6320234e27ffba034243403f8 159 SUPERFAMILY SSF51182 13 134 5.94E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS25020 6cab84b6320234e27ffba034243403f8 159 Pfam PF07883 Cupin domain 38 101 5.6E-17 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 Gene3D G3DSA:3.40.190.10 177 261 7.0E-18 T 06-07-2017 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 SUPERFAMILY SSF46785 3 109 2.26E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 SUPERFAMILY SSF53850 91 294 2.85E-31 T 06-07-2017 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.0E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 Gene3D G3DSA:3.40.190.10 91 176 5.7E-17 T 06-07-2017 CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 Gene3D G3DSA:1.10.10.10 3 88 6.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07895 c5379cc0a668d745d887cdd07615b814 307 Pfam PF03466 LysR substrate binding domain 90 293 1.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS04785 eb65a337ce7128b9d7c4517f8c8ae9b2 269 Pfam PF00005 ABC transporter 30 172 2.0E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04785 eb65a337ce7128b9d7c4517f8c8ae9b2 269 Gene3D G3DSA:3.40.50.300 7 221 1.2E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04785 eb65a337ce7128b9d7c4517f8c8ae9b2 269 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS04785 eb65a337ce7128b9d7c4517f8c8ae9b2 269 SUPERFAMILY SSF52540 9 227 6.76E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04785 eb65a337ce7128b9d7c4517f8c8ae9b2 269 SMART SM00382 39 222 3.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12030 628893cc8793c34a49263dcfbb495e50 126 Gene3D G3DSA:3.10.180.10 7 122 5.3E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS12030 628893cc8793c34a49263dcfbb495e50 126 SUPERFAMILY SSF54593 4 119 1.75E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS03600 ec40c0206be7560da96e73a76d14bc64 377 Gene3D G3DSA:2.120.10.30 1 376 7.6E-75 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS03600 ec40c0206be7560da96e73a76d14bc64 377 SUPERFAMILY SSF50952 1 370 7.19E-30 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK95_RS03600 ec40c0206be7560da96e73a76d14bc64 377 Pfam PF07995 Glucose / Sorbosone dehydrogenase 1 370 2.2E-59 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAK95_RS16095 224ff312335fe736aa2cd7b0cb4d69d7 155 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 148 9.0E-17 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS11020 1a6a6f569177348d26d70a4db2b9ba04 232 Gene3D G3DSA:3.90.550.10 1 229 2.7E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS11020 1a6a6f569177348d26d70a4db2b9ba04 232 Pfam PF12804 MobA-like NTP transferase domain 2 135 6.0E-15 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK95_RS11020 1a6a6f569177348d26d70a4db2b9ba04 232 SUPERFAMILY SSF53448 1 227 4.28E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS10555 ea7533cfda552671b076eb8198a05d06 1106 Pfam PF00271 Helicase conserved C-terminal domain 177 278 3.6E-9 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS10555 ea7533cfda552671b076eb8198a05d06 1106 SUPERFAMILY SSF52540 22 144 7.35E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10555 ea7533cfda552671b076eb8198a05d06 1106 SMART SM00490 190 279 2.8E-13 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS10555 ea7533cfda552671b076eb8198a05d06 1106 Gene3D G3DSA:3.40.50.300 178 283 5.9E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10555 ea7533cfda552671b076eb8198a05d06 1106 SUPERFAMILY SSF52540 154 405 2.3E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 Gene3D G3DSA:1.10.10.10 7 140 1.8E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 Pfam PF01047 MarR family 34 91 5.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 SMART SM00347 27 127 4.4E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09970 7b15bbc42fd63627c2fc30526535b243 156 SUPERFAMILY SSF46785 3 143 6.23E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 Pfam PF03705 CheR methyltransferase, all-alpha domain 26 77 2.5E-14 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 Pfam PF01739 CheR methyltransferase, SAM binding domain 91 286 1.4E-59 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 SUPERFAMILY SSF47757 17 90 9.68E-18 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 SMART SM00138 25 291 1.8E-94 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 SUPERFAMILY SSF53335 91 288 1.29E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 Gene3D G3DSA:3.40.50.150 90 289 1.5E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PIRSF PIRSF000410 11 292 9.6E-96 T 06-07-2017 IPR026024 Chemotaxis protein methyltransferase CheR CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 Gene3D G3DSA:1.10.155.10 17 88 7.1E-24 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 160 176 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 47 60 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 125 145 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 231 245 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 84 96 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS06065 431a8a8122be2d454562beaffaa21653 292 PRINTS PR00996 Glutamate methyltransferase family signature 250 273 4.0E-44 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAK95_RS25580 544b6cba91b492c648d484c870ff86d5 137 Gene3D G3DSA:2.170.150.20 7 136 1.8E-58 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS25580 544b6cba91b492c648d484c870ff86d5 137 SUPERFAMILY SSF51316 12 136 5.93E-57 T 06-07-2017 IPR011057 Mss4-like CAK95_RS25580 544b6cba91b492c648d484c870ff86d5 137 Pfam PF01641 SelR domain 17 135 3.8E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS25580 544b6cba91b492c648d484c870ff86d5 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 136 7.7E-49 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 PIRSF PIRSF006076 8 799 3.1E-251 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Pfam PF01103 Surface antigen 455 799 1.5E-93 T 06-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 23 799 23.238 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 43 799 8.8E-219 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Gene3D G3DSA:2.40.160.50 392 785 1.8E-19 T 06-07-2017 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Pfam PF07244 Surface antigen variable number repeat 273 352 3.9E-9 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Pfam PF07244 Surface antigen variable number repeat 356 427 4.5E-14 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Pfam PF07244 Surface antigen variable number repeat 184 270 7.6E-15 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAK95_RS22995 7648655393e42a31f2a53956be27f3fd 799 Pfam PF07244 Surface antigen variable number repeat 102 179 1.5E-13 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Pfam PF07687 Peptidase dimerisation domain 182 282 1.1E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Gene3D G3DSA:3.30.70.360 195 282 3.5E-25 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 3 385 47.829 T 06-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 SUPERFAMILY SSF55031 186 282 3.44E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Gene3D G3DSA:3.40.630.10 327 384 9.6E-72 T 06-07-2017 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Gene3D G3DSA:3.40.630.10 4 194 9.6E-72 T 06-07-2017 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 SUPERFAMILY SSF53187 4 185 1.81E-62 T 06-07-2017 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 SUPERFAMILY SSF53187 303 383 1.81E-62 T 06-07-2017 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 142 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 382 7.2E-121 T 06-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAK95_RS02805 eec38fde6b42ba947d546f6bde5b2b55 385 Pfam PF01546 Peptidase family M20/M25/M40 68 381 2.2E-44 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 571 704 4.4E-27 T 06-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Gene3D G3DSA:3.10.580.10 237 364 3.0E-20 T 06-07-2017 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 SMART SM00116 318 366 1.1E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 SMART SM00116 245 300 6.3 T 06-07-2017 IPR000644 CBS domain CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Pfam PF00929 Exonuclease 16 173 3.1E-32 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 16 180 5.4E-22 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Pfam PF00571 CBS domain 311 365 7.8E-7 T 06-07-2017 IPR000644 CBS domain CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Pfam PF00571 CBS domain 238 300 2.0E-6 T 06-07-2017 IPR000644 CBS domain CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 SUPERFAMILY SSF54631 236 372 1.02E-22 T 06-07-2017 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 SMART SM00479 14 182 2.8E-51 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 SUPERFAMILY SSF53098 15 187 1.39E-50 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Gene3D G3DSA:3.30.420.10 8 185 4.0E-54 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS13655 30607a808ac5fc5679ffdc0aed13d5b5 711 Pfam PF03445 Putative nucleotidyltransferase DUF294 391 532 1.4E-35 T 06-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 Pfam PF00120 Glutamine synthetase, catalytic domain 143 473 3.8E-77 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 SMART SM01230 141 405 2.1E-69 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 Gene3D G3DSA:3.10.20.70 27 142 6.9E-16 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 SUPERFAMILY SSF55931 141 491 7.95E-83 T 06-07-2017 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 Gene3D G3DSA:3.30.590.10 144 472 2.2E-77 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK95_RS09295 052dcccc59ed9eabb7d9737e5fa1687f 493 SUPERFAMILY SSF54368 27 140 2.35E-16 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 5 877 22.36 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 SUPERFAMILY SSF50677 227 418 1.47E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 SUPERFAMILY SSF52374 5 227 1.95E-147 T 06-07-2017 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 SUPERFAMILY SSF52374 430 678 1.95E-147 T 06-07-2017 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 501 519 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 540 562 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 573 583 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 216 235 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 154 170 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 128 145 2.0E-45 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Gene3D G3DSA:3.40.50.620 629 658 2.0E-150 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Gene3D G3DSA:3.40.50.620 5 223 2.0E-150 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Gene3D G3DSA:3.40.50.620 439 589 2.0E-150 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 SUPERFAMILY SSF47323 674 876 3.92E-30 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 222 413 9.1E-66 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Pfam PF09334 tRNA synthetases class I (M) 38 172 1.4E-18 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Pfam PF08264 Anticodon-binding domain of tRNA 716 837 8.5E-18 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Gene3D G3DSA:1.10.730.10 659 811 4.3E-39 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Gene3D G3DSA:3.90.740.10 224 438 4.7E-47 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 432 592 5.6E-9 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 629 668 1.5E-6 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS08170 306ae63853f7dec8d3dcaf5a768fd741 877 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 876 0.0 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 Pfam PF12697 Alpha/beta hydrolase family 26 246 4.3E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.1E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.1E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 2.1E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.1E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 SUPERFAMILY SSF53474 5 255 2.66E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28820 e6301444ae0092c0042d4df28bf9761f 259 Gene3D G3DSA:3.40.50.1820 10 255 1.6E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 Gene3D G3DSA:3.20.20.450 500 741 1.9E-96 T 06-07-2017 IPR001633 EAL domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 Pfam PF00563 EAL domain 504 733 1.7E-74 T 06-07-2017 IPR001633 EAL domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 323 485 1.4E-39 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 Gene3D G3DSA:3.30.70.270 327 493 1.8E-55 T 06-07-2017 CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 SUPERFAMILY SSF55073 330 488 2.28E-46 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 Pfam PF05228 CHASE4 domain 71 244 2.9E-13 T 06-07-2017 IPR007892 CHASE4 CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 Pfam PF00990 Diguanylate cyclase, GGDEF domain 325 483 1.1E-44 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 SUPERFAMILY SSF141868 502 737 8.24E-88 T 06-07-2017 IPR001633 EAL domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 SMART SM00052 497 738 2.2E-109 T 06-07-2017 IPR001633 EAL domain CAK95_RS20605 40ec2dcb12c080241a0b455709e891a6 761 SMART SM00267 314 487 5.9E-59 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 SMART SM00862 151 226 3.9E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 SUPERFAMILY SSF46894 126 227 5.95E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 SMART SM00448 5 117 1.7E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 Pfam PF00072 Response regulator receiver domain 7 118 1.3E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.7E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 SUPERFAMILY SSF52172 5 134 3.27E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 Gene3D G3DSA:1.10.10.10 128 227 2.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08200 4a09c02447efa40d90bbf9202b844b31 228 Gene3D G3DSA:3.40.50.2300 5 127 1.2E-34 T 06-07-2017 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 Gene3D G3DSA:3.40.50.300 343 570 5.5E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 SMART SM00382 368 553 6.4E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 Pfam PF00005 ABC transporter 360 507 7.0E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 SUPERFAMILY SSF52540 332 577 1.3E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 Gene3D G3DSA:1.20.1560.10 16 314 9.9E-35 T 06-07-2017 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 Pfam PF00664 ABC transporter transmembrane region 29 290 2.6E-18 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 SUPERFAMILY SSF90123 483 492 1.57E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 SUPERFAMILY SSF90123 16 307 1.57E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS10975 928bd4d1b3675f27315edd6999e1316c 600 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 4.9E-14 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 Pfam PF16912 Glucose dehydrogenase C-terminus 147 347 1.7E-61 T 06-07-2017 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 SUPERFAMILY SSF51735 146 283 2.73E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 Gene3D G3DSA:3.40.50.720 190 279 9.6E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 Gene3D G3DSA:3.90.180.10 10 189 5.8E-32 T 06-07-2017 IPR011032 GroES-like CAK95_RS11110 a7448ac859aab2183b49e280a8fd60a6 350 SUPERFAMILY SSF50129 11 184 5.17E-32 T 06-07-2017 IPR011032 GroES-like CAK95_RS08455 955657526c729142d95be64235e28151 331 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 321 34.252 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 SUPERFAMILY SSF48179 179 330 1.84E-47 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS08455 955657526c729142d95be64235e28151 331 Gene3D G3DSA:1.10.1040.10 184 325 1.8E-47 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS08455 955657526c729142d95be64235e28151 331 PIRSF PIRSF000114 1 331 9.6E-87 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 SUPERFAMILY SSF51735 2 180 2.9E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08455 955657526c729142d95be64235e28151 331 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 319 3.6E-44 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 2.1E-31 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS08455 955657526c729142d95be64235e28151 331 Gene3D G3DSA:3.40.50.720 2 183 5.8E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08455 955657526c729142d95be64235e28151 331 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 160 2.8E-39 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF81665 649 688 5.89E-15 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF81665 154 206 5.89E-15 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF81665 303 397 5.89E-15 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 175 677 6.2E-84 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 170 702 7.5E-125 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF81653 205 302 1.22E-24 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 405 411 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 152 495 2.6E-98 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Gene3D G3DSA:3.40.1110.10 418 528 9.0E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Pfam PF00122 E1-E2 ATPase 174 394 4.8E-65 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 152 702 2.4E-182 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Pfam PF00403 Heavy-metal-associated domain 10 69 8.9E-8 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 537 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 403 417 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 548 558 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 619 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 252 266 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 635 1.9E-28 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 21 42 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 10 19 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 268 284 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 287 301 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 207 223 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 PRINTS PR00941 Cadmium-transporting ATPase signature 187 207 3.6E-14 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Gene3D G3DSA:3.30.70.100 9 72 3.4E-16 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF56784 401 421 5.0E-51 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF56784 498 700 5.0E-51 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Gene3D G3DSA:2.70.150.10 169 303 6.1E-27 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 SUPERFAMILY SSF55008 6 73 1.96E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Pfam PF00702 haloacid dehalogenase-like hydrolase 400 614 6.8E-41 T 06-07-2017 CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Gene3D G3DSA:3.40.50.1000 378 417 1.1E-42 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19750 f20f0ca90d5ba1f6566a597d943d4ca2 716 Gene3D G3DSA:3.40.50.1000 529 668 1.1E-42 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS28875 f70c94eb7fe4f4db3928b9fde1190f14 177 SUPERFAMILY SSF53474 8 155 3.16E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28875 f70c94eb7fe4f4db3928b9fde1190f14 177 Gene3D G3DSA:3.40.50.1820 7 148 1.5E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28875 f70c94eb7fe4f4db3928b9fde1190f14 177 Pfam PF00561 alpha/beta hydrolase fold 28 141 4.5E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02440 07ef43fd03e999a55eb0dc75068104e0 251 Pfam PF06532 Protein of unknown function (DUF1109) 63 250 7.4E-36 T 06-07-2017 IPR009495 Protein of unknown function DUF1109 CAK95_RS06465 2e934a95cb3749cd82ba4fc9d693da83 89 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 82 7.0E-21 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CAK95_RS06465 2e934a95cb3749cd82ba4fc9d693da83 89 PIRSF PIRSF028784 1 89 2.1E-26 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CAK95_RS22080 e3bbce1c2cd0b72a3879e7554365e1b2 199 SMART SM01207 10 185 1.2E-82 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAK95_RS22080 e3bbce1c2cd0b72a3879e7554365e1b2 199 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 194 7.1E-56 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAK95_RS22080 e3bbce1c2cd0b72a3879e7554365e1b2 199 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 184 1.4E-51 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAK95_RS22080 e3bbce1c2cd0b72a3879e7554365e1b2 199 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 20.713 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAK95_RS02090 06dc1858e516caf21cbe07d5e62d6ae8 324 PIRSF PIRSF017082 1 323 1.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02090 06dc1858e516caf21cbe07d5e62d6ae8 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 316 1.3E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02090 06dc1858e516caf21cbe07d5e62d6ae8 324 SUPERFAMILY SSF53850 112 285 9.05E-12 T 06-07-2017 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF55961 712 960 7.46E-42 T 06-07-2017 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 735 959 8.0E-18 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF51905 128 314 3.2E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF50022 1 104 2.75E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF55424 442 522 6.45E-12 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:3.90.380.10 701 960 4.5E-48 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 131 428 6.4E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF50022 555 707 2.1E-42 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 733 755 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 573 598 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 625 645 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 646 666 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 604 619 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 694 720 1.2E-26 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Pfam PF14759 Reductase C-terminal 448 522 3.8E-10 T 06-07-2017 IPR028202 Reductase, C-terminal CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 SUPERFAMILY SSF51905 272 437 2.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:3.50.50.60 127 236 1.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:3.50.50.60 237 437 2.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:2.102.10.10 1 104 3.9E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 632 655 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:3.30.390.30 448 522 1.9E-12 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Gene3D G3DSA:2.102.10.10 589 700 8.4E-22 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Pfam PF00355 Rieske [2Fe-2S] domain 589 672 2.6E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS25490 81aa320229c5708e58757f3f6c314de9 961 Pfam PF00355 Rieske [2Fe-2S] domain 3 88 1.2E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS26245 48aa6deca420658e4e35936255bf2799 474 Pfam PF08309 LVIVD repeat 337 348 1.2 T 06-07-2017 IPR013211 LVIVD CAK95_RS26245 48aa6deca420658e4e35936255bf2799 474 Pfam PF08309 LVIVD repeat 387 418 0.03 T 06-07-2017 IPR013211 LVIVD CAK95_RS26245 48aa6deca420658e4e35936255bf2799 474 Pfam PF08309 LVIVD repeat 263 293 0.098 T 06-07-2017 IPR013211 LVIVD CAK95_RS26245 48aa6deca420658e4e35936255bf2799 474 Pfam PF08309 LVIVD repeat 185 204 0.019 T 06-07-2017 IPR013211 LVIVD CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 SMART SM00938 4 105 6.3E-66 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.2E-42 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 PIRSF PIRSF039144 1 112 1.5E-54 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 SUPERFAMILY SSF54913 1 112 6.35E-46 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 PRINTS PR00340 P-II protein signature 2 17 3.8E-45 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 PRINTS PR00340 P-II protein signature 52 75 3.8E-45 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 PRINTS PR00340 P-II protein signature 23 41 3.8E-45 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 PRINTS PR00340 P-II protein signature 83 103 3.8E-45 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS22680 fae213e683af8dd81993d1c78814630d 112 Gene3D G3DSA:3.30.70.120 1 112 5.8E-51 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 Gene3D G3DSA:1.10.1270.20 160 229 7.4E-28 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 SUPERFAMILY SSF75217 2 229 1.64E-90 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 Gene3D G3DSA:3.40.1280.10 3 159 5.1E-63 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 PIRSF PIRSF000386 3 236 5.6E-91 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 237 102.518 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 25 220 1.8E-52 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK95_RS07660 39d4e5e97531ebf770a7548319637e0d 237 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 6 231 1.3E-78 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK95_RS04295 320208c4da0572d903e4200f0ec0d421 324 SUPERFAMILY SSF53850 116 279 1.48E-9 T 06-07-2017 CAK95_RS04295 320208c4da0572d903e4200f0ec0d421 324 PIRSF PIRSF017082 1 322 6.3E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS04295 320208c4da0572d903e4200f0ec0d421 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 1.8E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SMART SM00889 474 591 4.6E-58 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SUPERFAMILY SSF50447 272 386 2.26E-12 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Gene3D G3DSA:3.30.70.870 400 474 8.0E-24 T 06-07-2017 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SUPERFAMILY SSF54211 473 592 3.29E-37 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Gene3D G3DSA:3.30.70.240 591 687 2.4E-17 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Pfam PF00009 Elongation factor Tu GTP binding domain 21 285 2.0E-31 T 06-07-2017 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SMART SM00838 593 683 1.6E-14 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Gene3D G3DSA:3.30.230.10 478 590 1.3E-41 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SUPERFAMILY SSF54980 596 687 2.11E-18 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Gene3D G3DSA:3.40.50.300 18 287 1.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 156 2.1E-13 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Gene3D G3DSA:2.40.30.10 304 388 1.1E-13 T 06-07-2017 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Pfam PF03764 Elongation factor G, domain IV 473 589 1.2E-38 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Pfam PF00679 Elongation factor G C-terminus 593 682 1.2E-19 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 Pfam PF14492 Elongation Factor G, domain II 400 469 1.7E-21 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SUPERFAMILY SSF52540 18 287 4.49E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13740 627357f4642c164eef535f30bcb93e7d 691 SUPERFAMILY SSF54980 400 475 1.29E-17 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS05385 334497a4e69fff2204ca2c9204485fc9 456 PIRSF PIRSF017901 1 456 3.3E-186 T 06-07-2017 CAK95_RS05385 334497a4e69fff2204ca2c9204485fc9 456 SUPERFAMILY SSF55931 23 267 1.28E-71 T 06-07-2017 CAK95_RS05385 334497a4e69fff2204ca2c9204485fc9 456 SUPERFAMILY SSF55931 306 454 1.28E-71 T 06-07-2017 CAK95_RS05385 334497a4e69fff2204ca2c9204485fc9 456 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 50 360 1.2E-107 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK95_RS05385 334497a4e69fff2204ca2c9204485fc9 456 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 10 456 2.6E-208 T 06-07-2017 IPR011556 Glutamate--cysteine ligase, plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK95_RS14705 69cfc8037639cbf677b1762f16bcd991 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 283 2.7E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14705 69cfc8037639cbf677b1762f16bcd991 292 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 30 286 8.0E-122 T 06-07-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CAK95_RS14705 69cfc8037639cbf677b1762f16bcd991 292 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 31 285 6.0E-97 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAK95_RS14705 69cfc8037639cbf677b1762f16bcd991 292 Gene3D G3DSA:1.10.3720.10 32 286 3.4E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14705 69cfc8037639cbf677b1762f16bcd991 292 SUPERFAMILY SSF161098 30 280 3.4E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 SUPERFAMILY SSF50974 35 368 1.15E-68 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 155 193 1.6E-9 T 06-07-2017 IPR011964 YVTN beta-propeller repeat CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 197 237 1.4E-10 T 06-07-2017 IPR011964 YVTN beta-propeller repeat CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 329 368 5.5E-11 T 06-07-2017 IPR011964 YVTN beta-propeller repeat CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 Gene3D G3DSA:2.130.10.10 53 371 4.8E-68 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS02385 6b51cc5876afe58cff738be6e8eb51d2 373 Pfam PF10282 Lactonase, 7-bladed beta-propeller 136 259 1.2E-8 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 Pfam PF01979 Amidohydrolase family 50 442 1.4E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 SUPERFAMILY SSF51338 356 462 2.73E-38 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 Gene3D G3DSA:2.30.40.10 382 460 8.0E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 Gene3D G3DSA:3.20.20.140 69 381 8.8E-112 T 06-07-2017 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 SUPERFAMILY SSF51556 54 388 3.09E-103 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 Gene3D G3DSA:2.30.40.10 4 68 9.4E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 SUPERFAMILY SSF51338 3 82 1.46E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS18585 c41ebacbe3b99b7b9454878b10a57ec7 471 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 460 6.8E-167 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CAK95_RS03255 f383e4d465c177614e66afadca6985e1 238 Gene3D G3DSA:3.40.50.300 4 229 1.0E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03255 f383e4d465c177614e66afadca6985e1 238 SUPERFAMILY SSF52540 6 232 8.72E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03255 f383e4d465c177614e66afadca6985e1 238 Pfam PF00005 ABC transporter 22 166 2.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS03255 f383e4d465c177614e66afadca6985e1 238 SMART SM00382 31 215 4.3E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS03255 f383e4d465c177614e66afadca6985e1 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.30.365.10 332 490 2.3E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 SUPERFAMILY SSF56003 628 723 9.29E-104 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 SUPERFAMILY SSF56003 255 600 9.29E-104 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 SUPERFAMILY SSF56003 774 939 9.29E-104 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.30.365.10 806 939 3.4E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.30.365.10 530 548 3.4E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.90.1170.50 49 173 1.1E-4 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 SUPERFAMILY SSF54665 49 174 2.79E-12 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.30.365.10 549 714 1.8E-18 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Gene3D G3DSA:3.30.365.10 789 805 1.8E-18 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27990 27a08409286e755f287f42cdaa6f7f81 940 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 260 878 1.2E-67 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26990 420fca8b81337d997b44b803b8ed2ea5 501 Gene3D G3DSA:3.40.50.150 45 199 8.3E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26990 420fca8b81337d997b44b803b8ed2ea5 501 SUPERFAMILY SSF53335 9 193 9.4E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26990 420fca8b81337d997b44b803b8ed2ea5 501 Pfam PF13704 Glycosyl transferase family 2 249 332 1.0E-8 T 06-07-2017 CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 255 4.6E-74 T 06-07-2017 CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 212 223 - T 06-07-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 1.8E-20 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 SUPERFAMILY SSF56219 2 255 5.63E-78 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 Gene3D G3DSA:3.60.10.10 2 255 1.5E-79 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 255 2.2E-70 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAK95_RS06440 8badc08fc629b9030c1bbecca3b7e206 277 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 06-07-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CAK95_RS12810 dfc7a2434dcb045cce54558b0d167842 82 Pfam PF11730 Protein of unknown function (DUF3297) 6 76 1.4E-40 T 06-07-2017 IPR021724 Protein of unknown function DUF3297 CAK95_RS18200 42b8a07e54680d548ce62ef41ee5a03f 330 Pfam PF13144 Chaperone for flagella basal body P-ring formation 152 303 1.1E-38 T 06-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CAK95_RS18200 42b8a07e54680d548ce62ef41ee5a03f 330 SMART SM00858 180 242 8.1E-11 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS18200 42b8a07e54680d548ce62ef41ee5a03f 330 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 171 303 1.5E-36 T 06-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CAK95_RS18200 42b8a07e54680d548ce62ef41ee5a03f 330 SUPERFAMILY SSF51269 180 239 7.69E-5 T 06-07-2017 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 SUPERFAMILY SSF53254 5 197 7.35E-64 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 SMART SM00855 5 166 2.1E-24 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 124 1.4E-52 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 185 4.6E-41 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 205 38.422 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 Gene3D G3DSA:3.40.50.1240 3 197 5.0E-77 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK95_RS08955 b062da3012edea535547dc8d1a3baa23 207 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAK95_RS16875 c8f7350186c0b7df8e853e13abcce100 272 SUPERFAMILY SSF161098 8 260 1.57E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16875 c8f7350186c0b7df8e853e13abcce100 272 Gene3D G3DSA:1.10.3720.10 12 260 1.6E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16875 c8f7350186c0b7df8e853e13abcce100 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 258 4.1E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10840 a6277a65ffdc2ff30358edb9c7abcca7 413 Pfam PF00534 Glycosyl transferases group 1 190 339 1.5E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS10840 a6277a65ffdc2ff30358edb9c7abcca7 413 Pfam PF13439 Glycosyltransferase Family 4 22 180 1.4E-20 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS10840 a6277a65ffdc2ff30358edb9c7abcca7 413 SUPERFAMILY SSF53756 14 374 6.28E-70 T 06-07-2017 CAK95_RS10840 a6277a65ffdc2ff30358edb9c7abcca7 413 Gene3D G3DSA:3.40.50.2000 191 346 5.6E-21 T 06-07-2017 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 PIRSF PIRSF000484 11 426 3.4E-61 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 21 424 6.2E-84 T 06-07-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 Gene3D G3DSA:3.20.140.10 3 410 9.4E-142 T 06-07-2017 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 191 426 8.2E-68 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 SUPERFAMILY SSF51690 140 425 9.22E-83 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 SUPERFAMILY SSF54675 4 158 7.06E-46 T 06-07-2017 CAK95_RS14050 3722637e5ae85599424cacf3af891909 435 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 18 428 38.316 T 06-07-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK95_RS26965 be327908397633845888823124157042 206 Gene3D G3DSA:3.40.50.150 37 117 5.1E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26965 be327908397633845888823124157042 206 SUPERFAMILY SSF53335 33 126 2.69E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26965 be327908397633845888823124157042 206 Pfam PF13578 Methyltransferase domain 44 146 9.9E-11 T 06-07-2017 CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 Gene3D G3DSA:3.10.580.10 238 350 1.5E-21 T 06-07-2017 CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 Pfam PF00571 CBS domain 298 345 5.3E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 Pfam PF00571 CBS domain 241 290 1.1E-7 T 06-07-2017 IPR000644 CBS domain CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 SUPERFAMILY SSF54631 240 351 6.32E-22 T 06-07-2017 CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 SMART SM00116 305 353 9.9 T 06-07-2017 IPR000644 CBS domain CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 SMART SM00116 242 290 2.9E-6 T 06-07-2017 IPR000644 CBS domain CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 PIRSF PIRSF006404 1 361 6.2E-109 T 06-07-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 Pfam PF02163 Peptidase family M50 47 118 1.0E-6 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAK95_RS08730 5a97cfcccb85cba5f2f661b4b93c2e1f 377 Pfam PF02163 Peptidase family M50 130 194 1.4E-7 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAK95_RS25015 92364f2b92a6231b9c26f5bac330ab9c 221 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 17 138 6.9E-8 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK95_RS25015 92364f2b92a6231b9c26f5bac330ab9c 221 Gene3D G3DSA:3.40.50.1820 3 212 7.1E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25015 92364f2b92a6231b9c26f5bac330ab9c 221 SUPERFAMILY SSF53474 4 212 1.1E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01285 8f7a1ba526157d3fa35c3cbbe869cd86 105 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 31 99 4.0E-24 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS01285 8f7a1ba526157d3fa35c3cbbe869cd86 105 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 27 97 7.6E-32 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS01285 8f7a1ba526157d3fa35c3cbbe869cd86 105 SMART SM01259 27 98 3.1E-43 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS01285 8f7a1ba526157d3fa35c3cbbe869cd86 105 PIRSF PIRSF028440 2 105 9.9E-40 T 06-07-2017 IPR014546 Uncharacterised conserved protein, lipid A biosynthesis CAK95_RS22910 17a8096b21fbe6f84e1eacc065522922 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 133 5.2E-51 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 CAK95_RS22910 17a8096b21fbe6f84e1eacc065522922 134 SUPERFAMILY SSF54593 1 133 3.62E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS22910 17a8096b21fbe6f84e1eacc065522922 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 1.0E-20 T 06-07-2017 CAK95_RS22910 17a8096b21fbe6f84e1eacc065522922 134 Gene3D G3DSA:3.10.180.10 1 133 1.0E-46 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Gene3D G3DSA:3.20.19.10 646 899 2.2E-82 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 SUPERFAMILY SSF53732 4 634 2.88E-223 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 ProSitePatterns PS00450 Aconitase family signature 1. 435 451 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Gene3D G3DSA:3.30.499.10 22 258 3.9E-81 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Pfam PF00694 Aconitase C-terminal domain 700 827 7.1E-46 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 899 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 SUPERFAMILY SSF52016 639 899 2.75E-90 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Pfam PF00330 Aconitase family (aconitate hydratase) 70 570 7.5E-188 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Gene3D G3DSA:3.30.499.10 379 583 4.0E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 ProSitePatterns PS01244 Aconitase family signature 2. 501 514 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 Gene3D G3DSA:3.40.1060.10 259 377 7.2E-36 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 212 225 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 501 514 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 439 450 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 226 241 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 382 396 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 302 315 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 288 301 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 171 179 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07560 143fa1e9e695fa0bc13c9232ad07d1d2 901 PRINTS PR00415 Aconitase family signature 147 160 7.7E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS22045 3bbc56a0fd111bdf131f5386e7c33caf 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 12.503 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS22045 3bbc56a0fd111bdf131f5386e7c33caf 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.0E-17 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS22045 3bbc56a0fd111bdf131f5386e7c33caf 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22045 3bbc56a0fd111bdf131f5386e7c33caf 55 SUPERFAMILY SSF57829 1 53 9.77E-17 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAK95_RS22045 3bbc56a0fd111bdf131f5386e7c33caf 55 Pfam PF00471 Ribosomal protein L33 7 53 2.4E-14 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 Gene3D G3DSA:3.40.50.2300 12 128 1.4E-28 T 06-07-2017 CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 Gene3D G3DSA:1.10.10.60 129 180 4.7E-29 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 SUPERFAMILY SSF52172 12 169 2.28E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 Pfam PF02954 Bacterial regulatory protein, Fis family 147 174 9.0E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 SMART SM00448 11 122 1.5E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06340 44c57626c50fa49204f9e8ffd1dd69ad 182 Pfam PF00072 Response regulator receiver domain 14 122 2.8E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 Gene3D G3DSA:2.30.40.10 360 374 1.4E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 Gene3D G3DSA:2.30.40.10 16 67 1.4E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 SUPERFAMILY SSF51338 360 388 2.81E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 SUPERFAMILY SSF51338 15 66 2.81E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 Gene3D G3DSA:3.20.20.140 68 359 1.8E-95 T 06-07-2017 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 PIRSF PIRSF038994 15 390 3.0E-101 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 SUPERFAMILY SSF51556 67 360 2.67E-92 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 Pfam PF01979 Amidohydrolase family 63 386 5.2E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS00765 2e6d5c56508b87790b456b65200beac7 395 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 20 386 2.2E-93 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 35 90 2.4E-12 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 SUPERFAMILY SSF46785 28 134 4.08E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 Gene3D G3DSA:3.40.190.10 115 201 4.2E-13 T 06-07-2017 CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 Pfam PF03466 LysR substrate binding domain 115 311 1.2E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 SUPERFAMILY SSF53850 115 315 3.67E-28 T 06-07-2017 CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 Gene3D G3DSA:1.10.10.10 29 107 1.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23700 d73f787e99e06f50697b85b74815c6f7 317 Gene3D G3DSA:3.40.190.10 202 283 7.6E-16 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 Pfam PF00206 Lyase 7 287 8.5E-50 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 7.2E-5 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00145 Argininosuccinate lyase family signature 264 280 7.2E-5 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00145 Argininosuccinate lyase family signature 219 243 7.2E-5 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 Gene3D G3DSA:1.20.200.10 94 359 2.3E-87 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 ProSitePatterns PS00163 Fumarate lyases signature. 264 273 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00149 Fumarate lyase superfamily signature 219 246 1.7E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 1.7E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00149 Fumarate lyase superfamily signature 264 280 1.7E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.7E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 SUPERFAMILY SSF48557 3 432 7.38E-129 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 SMART SM00998 352 432 2.1E-38 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 Gene3D G3DSA:1.10.40.30 360 432 2.2E-34 T 06-07-2017 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 353 431 1.8E-26 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 432 1.2E-153 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS20215 160af5577fedb7e9179743047edaba34 435 Gene3D G3DSA:1.10.275.10 2 93 1.0E-32 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Gene3D G3DSA:3.30.300.10 268 293 2.5E-50 T 06-07-2017 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Gene3D G3DSA:3.30.300.10 12 130 2.5E-50 T 06-07-2017 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 421 3.6E-136 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 269 411 1.3E-64 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Gene3D G3DSA:3.30.300.10 160 267 2.5E-25 T 06-07-2017 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 295 303 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 SUPERFAMILY SSF55973 269 422 1.84E-65 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 PIRSF PIRSF000497 1 423 2.6E-143 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 SUPERFAMILY SSF55973 4 131 2.98E-28 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 SUPERFAMILY SSF55973 135 268 3.92E-34 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Pfam PF02772 S-adenosylmethionine synthetase, central domain 140 267 5.1E-32 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Gene3D G3DSA:3.30.300.10 294 422 2.4E-66 T 06-07-2017 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 141 151 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS09195 5236ced750b310a7d003234afc9011a4 423 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 123 4.4E-29 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK95_RS11035 7763f51a6fce83866f45cbcc0dff46f7 138 Pfam PF02082 Transcriptional regulator 4 83 4.9E-19 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS11035 7763f51a6fce83866f45cbcc0dff46f7 138 SUPERFAMILY SSF46785 5 132 1.15E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11035 7763f51a6fce83866f45cbcc0dff46f7 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 4 130 3.0E-22 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS11035 7763f51a6fce83866f45cbcc0dff46f7 138 Gene3D G3DSA:1.10.10.10 5 134 1.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF81665 227 329 3.92E-82 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF81665 629 834 3.92E-82 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF81665 26 130 3.92E-82 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Pfam PF00122 E1-E2 ATPase 98 326 2.1E-60 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 39 796 1.3E-282 T 06-07-2017 IPR006534 P-type ATPase, subfamily IIIA GO:0006754|GO:0016021|GO:0016887 KEGG: 00190+3.6.3.6 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF81653 130 227 3.14E-28 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:2.70.150.10 125 227 4.0E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:2.70.150.10 37 72 4.0E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 546 660 7.8E-28 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 102 523 1.7E-57 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Pfam PF00690 Cation transporter/ATPase, N-terminus 25 87 6.9E-14 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 611 636 1.6E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 552 568 1.6E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 751 772 1.6E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 447 465 1.6E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 580 596 1.6E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:3.40.1110.10 350 468 1.3E-17 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 603 615 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 488 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 599 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 509 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 177 191 1.8E-38 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF56784 333 353 2.62E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SUPERFAMILY SSF56784 426 673 2.62E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 SMART SM00831 20 92 3.4E-17 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 594 7.2E-25 T 06-07-2017 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:1.20.1110.10 549 831 6.5E-90 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:1.20.1110.10 73 124 6.5E-90 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK95_RS26755 379e777af039c808227d2bdb22f3817b 851 Gene3D G3DSA:3.40.1110.10 325 349 1.5E-6 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS04625 7cde976ea5a3abc33f9dca9acbd1bcc0 262 Pfam PF13489 Methyltransferase domain 52 216 8.9E-9 T 06-07-2017 CAK95_RS04625 7cde976ea5a3abc33f9dca9acbd1bcc0 262 SUPERFAMILY SSF53335 50 220 3.71E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS04625 7cde976ea5a3abc33f9dca9acbd1bcc0 262 Gene3D G3DSA:3.40.50.150 52 254 7.0E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 SUPERFAMILY SSF81442 22 538 7.19E-220 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 35 485 3.1E-157 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 365 383 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 412 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 306 321 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 102 126 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 180 198 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 351 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 443 464 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 228 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 260 281 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 262 316 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 27 537 1.9E-219 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS05475 03305ad06177a22048595fefdf641d75 539 Gene3D G3DSA:1.20.210.10 38 506 1.6E-234 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 ProSitePatterns PS01176 Initiation factor 2 signature. 820 842 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 SUPERFAMILY SSF50447 771 867 1.3E-31 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 SUPERFAMILY SSF52156 653 776 2.35E-36 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 290 340 4.0E-12 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Pfam PF00009 Elongation factor Tu GTP binding domain 370 526 7.4E-33 T 06-07-2017 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Gene3D G3DSA:2.40.30.10 771 867 1.4E-36 T 06-07-2017 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Gene3D G3DSA:3.40.50.10050 670 748 2.8E-24 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 9 867 16.992 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 SUPERFAMILY SSF50447 540 623 9.03E-26 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 283 869 6.6E-240 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 16 53 3.7E-10 T 06-07-2017 IPR013575 Initiation factor 2 associated domain, bacterial CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 SUPERFAMILY SSF52540 363 538 2.02E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Pfam PF03144 Elongation factor Tu domain 2 790 857 4.3E-7 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 369 523 1.2E-30 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Pfam PF11987 Translation-initiation factor 2 654 759 4.3E-37 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Gene3D G3DSA:3.40.50.300 364 526 5.9E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09165 c3ac5894f9e34ee9ed8455b6fbf59361 869 Gene3D G3DSA:2.40.30.10 538 631 1.3E-24 T 06-07-2017 CAK95_RS12370 87208cc26114acc888eeb36f040d6b60 262 SUPERFAMILY SSF52540 9 258 3.48E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12370 87208cc26114acc888eeb36f040d6b60 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 3.0E-11 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS12370 87208cc26114acc888eeb36f040d6b60 262 Gene3D G3DSA:3.40.50.300 7 258 1.6E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12370 87208cc26114acc888eeb36f040d6b60 262 Pfam PF00005 ABC transporter 27 186 4.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12370 87208cc26114acc888eeb36f040d6b60 262 SMART SM00382 35 235 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23235 c1b2df3ba521ddb72e35993c09617f19 173 Gene3D G3DSA:3.90.950.20 3 163 5.9E-57 T 06-07-2017 IPR008136 CinA, C-terminal CAK95_RS23235 c1b2df3ba521ddb72e35993c09617f19 173 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 16 158 2.0E-46 T 06-07-2017 IPR008136 CinA, C-terminal CAK95_RS23235 c1b2df3ba521ddb72e35993c09617f19 173 Pfam PF02464 Competence-damaged protein 9 160 3.8E-54 T 06-07-2017 IPR008136 CinA, C-terminal CAK95_RS23235 c1b2df3ba521ddb72e35993c09617f19 173 SUPERFAMILY SSF142433 3 161 1.44E-54 T 06-07-2017 IPR008136 CinA, C-terminal CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 SUPERFAMILY SSF52540 403 714 7.65E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 SMART SM00382 459 664 8.0E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 Pfam PF09397 Ftsk gamma domain 748 807 8.1E-27 T 06-07-2017 IPR018541 FtsK gamma domain CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 SUPERFAMILY SSF46785 747 809 7.89E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 Gene3D G3DSA:3.40.50.300 401 708 5.1E-96 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 25 178 5.7E-28 T 06-07-2017 IPR025199 DNA translocase FtsK, 4TM region CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 SMART SM00843 746 810 5.3E-35 T 06-07-2017 IPR018541 FtsK gamma domain CAK95_RS08595 b8f84daf2c2e3d47c4f90badd93e73c7 815 Pfam PF01580 FtsK/SpoIIIE family 425 643 6.3E-65 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK95_RS24180 852f3cce0ca1d5eb2152b7d98952c3bb 412 Gene3D G3DSA:3.30.70.270 223 382 3.0E-49 T 06-07-2017 CAK95_RS24180 852f3cce0ca1d5eb2152b7d98952c3bb 412 SMART SM00267 209 382 1.5E-50 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS24180 852f3cce0ca1d5eb2152b7d98952c3bb 412 SUPERFAMILY SSF55073 226 381 2.75E-43 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS24180 852f3cce0ca1d5eb2152b7d98952c3bb 412 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 380 1.6E-43 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS24180 852f3cce0ca1d5eb2152b7d98952c3bb 412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 377 3.3E-41 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 198 0.0046 T 06-07-2017 CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 SUPERFAMILY SSF51735 13 257 5.03E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 Pfam PF00106 short chain dehydrogenase 13 204 2.1E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS26765 2c7e94a6d5c88a7c767fd38b5af072cf 267 Gene3D G3DSA:3.40.50.720 13 229 1.2E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 SUPERFAMILY SSF52540 5 224 6.83E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 Pfam PF00005 ABC transporter 22 160 1.5E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 Gene3D G3DSA:3.40.50.300 22 224 3.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 SMART SM00382 22 209 9.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 2 222 5.9E-90 T 06-07-2017 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 CAK95_RS06985 93ffe450f440c4cee6f5392e2c783ccb 228 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 392 646 1.1E-32 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 368 5.8E-38 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 592 663 1.8E-17 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 SUPERFAMILY SSF117143 83 186 8.24E-44 T 06-07-2017 CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 SUPERFAMILY SSF117143 422 625 8.24E-44 T 06-07-2017 CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 Pfam PF07196 Flagellin hook IN motif 244 292 2.1E-9 T 06-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 CAK95_RS18120 1621d8e0600481969ea5de63f2d8ccb8 665 Pfam PF00460 Flagella basal body rod protein 7 37 5.7E-6 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 Gene3D G3DSA:3.40.190.10 93 178 1.2E-18 T 06-07-2017 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 SUPERFAMILY SSF53850 94 300 3.1E-35 T 06-07-2017 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.4E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 SUPERFAMILY SSF46785 5 115 3.06E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 Gene3D G3DSA:1.10.10.10 8 91 6.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 Pfam PF03466 LysR substrate binding domain 91 295 6.4E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS13220 2579f241fb57a6b1328d26c0f555eed9 310 Gene3D G3DSA:3.40.190.10 179 265 8.8E-15 T 06-07-2017 CAK95_RS08375 3ea5e5a497ef0de81045bdf0001d609e 335 Pfam PF09084 NMT1/THI5 like 39 238 6.8E-23 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS08375 3ea5e5a497ef0de81045bdf0001d609e 335 Gene3D G3DSA:3.40.190.10 111 237 1.2E-5 T 06-07-2017 CAK95_RS08375 3ea5e5a497ef0de81045bdf0001d609e 335 SUPERFAMILY SSF53850 26 255 7.06E-21 T 06-07-2017 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 SMART SM00382 36 236 4.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 SMART SM00382 313 505 7.3E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Pfam PF00005 ABC transporter 305 456 2.3E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Pfam PF00005 ABC transporter 28 186 3.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 268 1.0E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 507 536 0.0022 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 SUPERFAMILY SSF52540 7 258 1.61E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Gene3D G3DSA:3.40.50.300 5 261 2.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 Gene3D G3DSA:3.40.50.300 277 528 1.2E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06705 39980c1719cf919e3e8c7159452e1d34 539 SUPERFAMILY SSF52540 277 527 1.22E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22900 be31136073215504ae370c56b3534596 283 Gene3D G3DSA:2.30.30.100 227 269 3.2E-7 T 06-07-2017 CAK95_RS22900 be31136073215504ae370c56b3534596 283 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 16 270 3.3E-36 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS22900 be31136073215504ae370c56b3534596 283 SUPERFAMILY SSF55681 10 223 1.17E-40 T 06-07-2017 CAK95_RS22900 be31136073215504ae370c56b3534596 283 SUPERFAMILY SSF50037 227 271 1.05E-7 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal CAK95_RS22900 be31136073215504ae370c56b3534596 283 Pfam PF03099 Biotin/lipoate A/B protein ligase family 21 164 7.2E-9 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAK95_RS22900 be31136073215504ae370c56b3534596 283 Gene3D G3DSA:3.30.930.10 8 222 2.7E-47 T 06-07-2017 CAK95_RS22900 be31136073215504ae370c56b3534596 283 Pfam PF02237 Biotin protein ligase C terminal domain 227 272 5.1E-5 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS00495 0fa1323f758a00b535117614e1b9ff97 673 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 39 634 7.0E-168 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein CAK95_RS00495 0fa1323f758a00b535117614e1b9ff97 673 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 134 554 3.5E-71 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS25820 217119d59c34e3d92257eb2c1cab9ddf 150 Gene3D G3DSA:3.40.50.10110 2 139 6.3E-40 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAK95_RS25820 217119d59c34e3d92257eb2c1cab9ddf 150 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 134 6.0E-36 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAK95_RS25820 217119d59c34e3d92257eb2c1cab9ddf 150 SUPERFAMILY SSF102400 2 139 1.57E-41 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAK95_RS12155 2b4a140a7c56e4528407c301c5688963 280 SMART SM00830 16 96 1.2E-17 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK95_RS12155 2b4a140a7c56e4528407c301c5688963 280 Pfam PF01817 Chorismate mutase type II 16 93 1.4E-14 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK95_RS12155 2b4a140a7c56e4528407c301c5688963 280 SUPERFAMILY SSF48600 9 95 1.07E-15 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK95_RS12155 2b4a140a7c56e4528407c301c5688963 280 Gene3D G3DSA:1.20.59.10 4 94 4.0E-13 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK95_RS02875 910a7e6c15793f56088703a6de6a7f61 226 SUPERFAMILY SSF53335 41 209 5.45E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02875 910a7e6c15793f56088703a6de6a7f61 226 Pfam PF13578 Methyltransferase domain 66 185 4.8E-21 T 06-07-2017 CAK95_RS02875 910a7e6c15793f56088703a6de6a7f61 226 Gene3D G3DSA:3.40.50.150 55 188 1.0E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 Gene3D G3DSA:3.40.50.10730 133 339 1.8E-79 T 06-07-2017 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 PIRSF PIRSF001423 1 548 1.1E-241 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 Gene3D G3DSA:3.40.1770.10 351 542 5.9E-113 T 06-07-2017 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 Gene3D G3DSA:3.40.1770.10 4 132 5.9E-113 T 06-07-2017 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 SUPERFAMILY SSF111326 3 544 3.79E-220 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 542 1.1E-209 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 Hamap MF_00577 Urocanate hydratase [hutU]. 1 547 42.75 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS01175 464f030fe1f2256f9bc2d53df2945220 549 Pfam PF01175 Urocanase 9 537 1.7E-220 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 102 116 1.2E-9 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 186 198 1.2E-9 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 46 61 1.2E-9 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 SUPERFAMILY SSF50494 19 244 7.93E-36 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 56 61 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 Pfam PF00089 Trypsin 26 239 4.0E-25 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 Gene3D G3DSA:2.40.10.10 33 108 2.0E-12 T 06-07-2017 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 Gene3D G3DSA:2.40.10.10 109 244 7.6E-15 T 06-07-2017 CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 187 198 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site CAK95_RS19025 a115476325e31ab524591206a6385ce6 251 SMART SM00020 20 239 1.9E-12 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAK95_RS00605 057227ef72d210fb3d462c6b318edf07 221 Gene3D G3DSA:3.90.79.10 56 219 6.0E-43 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS00605 057227ef72d210fb3d462c6b318edf07 221 Pfam PF00293 NUDIX domain 61 173 1.4E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS00605 057227ef72d210fb3d462c6b318edf07 221 SUPERFAMILY SSF55811 55 211 2.03E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 Gene3D G3DSA:3.30.390.50 180 284 4.3E-30 T 06-07-2017 CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 SUPERFAMILY SSF55447 182 284 1.23E-24 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 185 282 1.3E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 SMART SM01092 182 283 3.1E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 Gene3D G3DSA:3.30.43.10 1 55 1.1E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 Gene3D G3DSA:3.30.465.10 61 175 4.9E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 175 3.7E-37 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS27790 73eb8e83f6f14f24341fbf97ff27ddd1 285 SUPERFAMILY SSF56176 1 175 5.14E-43 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS13930 8620bf77d5b3f453da25448319d15105 263 Pfam PF05013 N-formylglutamate amidohydrolase 24 231 1.1E-43 T 06-07-2017 IPR007709 N-formylglutamate amidohydrolase CAK95_RS13930 8620bf77d5b3f453da25448319d15105 263 PIRSF PIRSF029730 2 259 3.8E-93 T 06-07-2017 IPR011227 Uncharacterised conserved protein UCP029730 CAK95_RS13930 8620bf77d5b3f453da25448319d15105 263 Gene3D G3DSA:3.40.630.40 15 251 7.0E-79 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS13930 8620bf77d5b3f453da25448319d15105 263 SUPERFAMILY SSF53187 10 250 3.77E-72 T 06-07-2017 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 SUPERFAMILY SSF55347 153 315 3.74E-71 T 06-07-2017 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 5.0E-129 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 SMART SM00846 3 153 6.8E-94 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 SUPERFAMILY SSF51735 1 180 7.32E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 2.0E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.0E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.0E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.0E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.0E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 3.8E-66 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 Gene3D G3DSA:3.30.360.10 162 316 7.9E-76 T 06-07-2017 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 PIRSF PIRSF000149 1 335 2.1E-137 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 2.8E-56 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04145 86cf77d27afff03e7098aaafd9d7cd64 335 Gene3D G3DSA:3.40.50.720 1 161 7.6E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 Pfam PF06463 Molybdenum Cofactor Synthesis C 199 325 2.7E-37 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 SUPERFAMILY SSF102114 17 291 1.14E-73 T 06-07-2017 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 Gene3D G3DSA:3.20.20.70 17 322 4.2E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 Pfam PF13353 4Fe-4S single cluster domain 34 139 4.5E-9 T 06-07-2017 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 18 346 39.258 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 Pfam PF04055 Radical SAM superfamily 31 193 1.5E-25 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 33 44 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 18 346 2.3E-108 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS19880 29ecd6d5bc51cdf73ce854803de4a2d3 346 SMART SM00729 27 228 4.7E-4 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 SUPERFAMILY SSF53901 1 261 8.3E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 SUPERFAMILY SSF53901 222 417 2.65E-70 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 SMART SM00825 Beta-ketoacyl synthase 4 418 7.0E-16 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 Gene3D G3DSA:3.40.47.10 270 417 2.4E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 375 1.1E-35 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 416 3.8E-190 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 Gene3D G3DSA:3.40.47.10 1 267 6.9E-77 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 254 6.5E-60 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK95_RS25885 3f0a34f0a7125ccb5562584af61f0a6f 418 PIRSF PIRSF000447 1 418 2.2E-192 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAK95_RS16690 61d8f0ef44194cca13cc235890da5fe5 57 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 1.7E-20 T 06-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type CAK95_RS16690 61d8f0ef44194cca13cc235890da5fe5 57 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 1.3E-23 T 06-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type CAK95_RS08335 ad73d8e7b96a93d28a515628830b1803 275 Gene3D G3DSA:3.40.50.300 7 234 1.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08335 ad73d8e7b96a93d28a515628830b1803 275 Pfam PF00005 ABC transporter 28 174 5.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS08335 ad73d8e7b96a93d28a515628830b1803 275 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS08335 ad73d8e7b96a93d28a515628830b1803 275 SUPERFAMILY SSF52540 8 249 4.26E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08335 ad73d8e7b96a93d28a515628830b1803 275 SMART SM00382 37 225 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS18450 d27c499deca2688903687472929feef0 235 SUPERFAMILY SSF46689 33 112 1.08E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS18450 d27c499deca2688903687472929feef0 235 Gene3D G3DSA:1.10.357.10 38 209 6.3E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS18450 d27c499deca2688903687472929feef0 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS18450 d27c499deca2688903687472929feef0 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS18450 d27c499deca2688903687472929feef0 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 93 4.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17310 42a1e9079fd216cf8301c563c13b7f98 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 230 7.5E-101 T 06-07-2017 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CAK95_RS17310 42a1e9079fd216cf8301c563c13b7f98 231 Pfam PF00005 ABC transporter 17 160 1.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17310 42a1e9079fd216cf8301c563c13b7f98 231 Gene3D G3DSA:3.40.50.300 1 222 1.0E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17310 42a1e9079fd216cf8301c563c13b7f98 231 SMART SM00382 26 210 4.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17310 42a1e9079fd216cf8301c563c13b7f98 231 SUPERFAMILY SSF52540 2 220 1.36E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00230 4dced2555f89497a8c93177708e57b34 321 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 42 299 1.1E-29 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS01265 193ba86c95a444e7b99dffc1152de42e 415 Pfam PF01734 Patatin-like phospholipase 85 267 7.4E-17 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS01265 193ba86c95a444e7b99dffc1152de42e 415 SUPERFAMILY SSF52151 82 300 3.66E-34 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS01265 193ba86c95a444e7b99dffc1152de42e 415 Gene3D G3DSA:3.40.1090.10 73 267 3.0E-15 T 06-07-2017 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 Pfam PF00034 Cytochrome c 27 102 2.5E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 SUPERFAMILY SSF46626 29 102 1.65E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 PRINTS PR00606 Class ID cytochrome C signature 27 40 5.3E-20 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 PRINTS PR00606 Class ID cytochrome C signature 65 78 5.3E-20 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 PRINTS PR00606 Class ID cytochrome C signature 42 55 5.3E-20 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 PRINTS PR00606 Class ID cytochrome C signature 92 102 5.3E-20 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 PRINTS PR00606 Class ID cytochrome C signature 80 90 5.3E-20 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAK95_RS03595 cd7332ccc1de1e6b096a568b429c32e3 104 Gene3D G3DSA:1.10.760.10 26 103 4.6E-29 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 Pfam PF03466 LysR substrate binding domain 89 293 2.5E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 Gene3D G3DSA:3.40.190.10 91 176 1.9E-16 T 06-07-2017 CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 Gene3D G3DSA:1.10.10.10 3 88 3.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 SUPERFAMILY SSF53850 91 295 3.73E-34 T 06-07-2017 CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 SUPERFAMILY SSF46785 2 112 5.99E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28660 e064cb9b3e8d72d3cd2f096103013d75 300 Gene3D G3DSA:3.40.190.10 177 261 2.7E-14 T 06-07-2017 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 123 4.9E-30 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 10 34 - T 06-07-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 SUPERFAMILY SSF81343 6 126 2.78E-34 T 06-07-2017 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 85 98 - T 06-07-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 127 7.5E-40 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 Gene3D G3DSA:1.20.1300.10 7 127 9.9E-42 T 06-07-2017 CAK95_RS07830 fa45ddd64b0ce828c61224a5fda01fd4 136 PIRSF PIRSF000178 1 129 1.9E-39 T 06-07-2017 CAK95_RS26070 90f2b5f13f164a7561a8794398e2cf42 375 Pfam PF01168 Alanine racemase, N-terminal domain 13 237 1.8E-33 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK95_RS26070 90f2b5f13f164a7561a8794398e2cf42 375 Pfam PF14031 Putative serine dehydratase domain 253 359 1.5E-19 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAK95_RS26070 90f2b5f13f164a7561a8794398e2cf42 375 SUPERFAMILY SSF51419 13 246 4.09E-36 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS26070 90f2b5f13f164a7561a8794398e2cf42 375 Gene3D G3DSA:3.20.20.10 17 234 2.1E-23 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS26070 90f2b5f13f164a7561a8794398e2cf42 375 SMART SM01119 253 362 9.5E-39 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 SUPERFAMILY SSF51735 2 249 3.0E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 Pfam PF00106 short chain dehydrogenase 6 203 5.2E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 Gene3D G3DSA:3.40.50.720 2 249 1.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS06200 4ab79f6e0e02737930f8926545b321d0 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 0.0019 T 06-07-2017 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 309 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 1.4E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 1.4E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 Gene3D G3DSA:1.10.10.60 214 265 1.5E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 Pfam PF12833 Helix-turn-helix domain 237 313 4.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 SUPERFAMILY SSF46689 265 314 5.38E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 Gene3D G3DSA:1.10.10.60 266 314 1.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 SMART SM00342 230 313 7.9E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS21230 35f0e08c6b488f1120d8e794161be928 317 Pfam PF14525 AraC-binding-like domain 18 192 2.7E-11 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS13005 d25828f6f8624ff518f5ffe2d1e29059 266 SUPERFAMILY SSF52540 14 262 4.35E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13005 d25828f6f8624ff518f5ffe2d1e29059 266 SMART SM00382 40 241 8.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13005 d25828f6f8624ff518f5ffe2d1e29059 266 Pfam PF00005 ABC transporter 32 192 1.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13005 d25828f6f8624ff518f5ffe2d1e29059 266 Gene3D G3DSA:3.40.50.300 13 262 1.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13005 d25828f6f8624ff518f5ffe2d1e29059 266 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 242 263 1.1E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 Pfam PF13174 Tetratricopeptide repeat 322 354 2.6E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 247 360 1.9E-36 T 06-07-2017 IPR014162 Tol-Pal system, YbgF CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 Pfam PF13432 Tetratricopeptide repeat 252 308 2.0E-10 T 06-07-2017 CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 SUPERFAMILY SSF48452 245 357 1.16E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 Gene3D G3DSA:1.25.40.10 240 354 1.3E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS03975 440c4f646fceb601de15cf81d1b3c5ce 371 Pfam PF16331 TolA binding protein trimerisation 18 71 6.8E-7 T 06-07-2017 IPR032519 YbgF, trimerisation domain GO:0070206 CAK95_RS24205 41624739323317f92ae8b4276beec570 383 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 167 265 3.1E-18 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS24205 41624739323317f92ae8b4276beec570 383 SUPERFAMILY SSF161098 167 356 1.22E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24205 41624739323317f92ae8b4276beec570 383 Gene3D G3DSA:1.10.3720.10 167 375 2.1E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24205 41624739323317f92ae8b4276beec570 383 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 187 374 1.6E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 206 224 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 77 95 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 SUPERFAMILY SSF51120 275 433 2.75E-22 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 SUPERFAMILY SSF51120 31 131 8.76E-18 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 SUPERFAMILY SSF51120 147 256 8.76E-14 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 PRINTS PR00313 NodO calcium binding signature 298 306 5.6E-10 T 06-07-2017 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 PRINTS PR00313 NodO calcium binding signature 210 218 5.6E-10 T 06-07-2017 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 PRINTS PR00313 NodO calcium binding signature 96 107 5.6E-10 T 06-07-2017 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 PRINTS PR00313 NodO calcium binding signature 316 325 5.6E-10 T 06-07-2017 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 218 234 0.096 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 54 69 61.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 71 88 0.011 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 279 291 2.5 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 179 193 11.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 90 105 0.074 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 203 217 0.0031 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 316 332 0.23 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 297 314 0.043 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 215 233 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Gene3D G3DSA:2.150.10.10 278 384 5.7E-19 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Gene3D G3DSA:2.150.10.10 30 127 1.9E-17 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS20995 79f2e8af9d7cb20035a17a48afb7d941 436 Gene3D G3DSA:2.150.10.10 134 256 4.9E-16 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS27515 16c53d777404bda44da2d08d92d1bee8 192 Pfam PF02563 Polysaccharide biosynthesis/export protein 39 112 6.6E-20 T 06-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CAK95_RS27515 16c53d777404bda44da2d08d92d1bee8 192 Pfam PF10531 SLBB domain 120 169 3.5E-8 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS27515 16c53d777404bda44da2d08d92d1bee8 192 Gene3D G3DSA:3.10.560.10 110 167 5.2E-9 T 06-07-2017 CAK95_RS27515 16c53d777404bda44da2d08d92d1bee8 192 Gene3D G3DSA:3.30.1950.10 46 109 3.7E-18 T 06-07-2017 CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 Pfam PF13406 Transglycosylase SLT domain 33 240 8.1E-77 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 32 239 3.5E-81 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 Gene3D G3DSA:1.10.530.10 239 270 9.5E-5 T 06-07-2017 CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 Gene3D G3DSA:1.10.530.10 78 134 6.0E-25 T 06-07-2017 CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 Gene3D G3DSA:1.10.530.10 215 238 6.0E-25 T 06-07-2017 CAK95_RS14010 1d377159cea90e93be599435eee0865c 271 SUPERFAMILY SSF53955 22 270 7.65E-75 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS12100 0befa375f3107ad694d2b8566b1793c9 321 Pfam PF09084 NMT1/THI5 like 24 233 5.2E-17 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS12100 0befa375f3107ad694d2b8566b1793c9 321 SUPERFAMILY SSF53850 16 240 8.51E-28 T 06-07-2017 CAK95_RS12100 0befa375f3107ad694d2b8566b1793c9 321 Gene3D G3DSA:3.40.190.10 108 186 4.9E-9 T 06-07-2017 CAK95_RS21105 157e35a90621dd20f99f8afb84e01453 180 Pfam PF02566 OsmC-like protein 71 178 9.1E-21 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS21105 157e35a90621dd20f99f8afb84e01453 180 Gene3D G3DSA:3.30.300.20 9 171 1.4E-38 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS21105 157e35a90621dd20f99f8afb84e01453 180 SUPERFAMILY SSF82784 15 178 1.1E-31 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 SUPERFAMILY SSF51905 11 179 7.13E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 SUPERFAMILY SSF51905 277 369 7.13E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 Pfam PF01494 FAD binding domain 10 343 5.9E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 1.1E-12 T 06-07-2017 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.1E-12 T 06-07-2017 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.1E-12 T 06-07-2017 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 SUPERFAMILY SSF54373 184 283 3.73E-17 T 06-07-2017 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 Gene3D G3DSA:3.50.50.60 277 357 2.8E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS22300 9fd41ca25f9757f62bf623700570a6d6 394 Gene3D G3DSA:3.50.50.60 12 185 2.8E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 312 5.0E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 Pfam PF00005 ABC transporter 46 195 5.4E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 333 3.2E-26 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 SMART SM00382 55 245 1.2E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 Gene3D G3DSA:3.40.50.300 17 275 1.1E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26705 fd8e39426a32126fa352b232985f842d 353 SUPERFAMILY SSF52540 20 266 2.79E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 SUPERFAMILY SSF52821 2 175 7.73E-32 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 SUPERFAMILY SSF52821 151 282 1.02E-30 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 Gene3D G3DSA:3.40.250.10 145 287 2.8E-30 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 Gene3D G3DSA:3.40.250.10 3 138 1.7E-30 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 Pfam PF00581 Rhodanese-like domain 155 271 6.0E-16 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 Pfam PF00581 Rhodanese-like domain 7 120 4.7E-20 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 SMART SM00450 6 124 2.2E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 SMART SM00450 148 275 3.3E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS21095 21aa4431fb6ac66e772147c1dee2112c 293 ProSitePatterns PS00380 Rhodanese signature 1. 31 42 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 Gene3D G3DSA:2.40.170.20 300 836 2.4E-153 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 Gene3D G3DSA:2.170.130.10 178 296 2.8E-40 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 Gene3D G3DSA:2.170.130.10 125 135 2.8E-40 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 Pfam PF00593 TonB dependent receptor 599 835 7.0E-30 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 Pfam PF07715 TonB-dependent Receptor Plug Domain 188 286 9.7E-24 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 188 834 2.0E-127 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 SUPERFAMILY SSF56935 178 836 1.9E-141 T 06-07-2017 CAK95_RS18255 77e8bbf1e92066431bcbc197a861fe43 836 SUPERFAMILY SSF56935 123 135 1.9E-141 T 06-07-2017 CAK95_RS11195 dc1e1398666198fdd0207dba3c8554d5 233 SUPERFAMILY SSF53098 25 215 2.58E-64 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS11195 dc1e1398666198fdd0207dba3c8554d5 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 34 212 33.593 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 CAK95_RS11195 dc1e1398666198fdd0207dba3c8554d5 233 Gene3D G3DSA:3.30.420.10 35 172 2.2E-43 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS11195 dc1e1398666198fdd0207dba3c8554d5 233 Pfam PF01351 Ribonuclease HII 36 211 1.1E-36 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain CAK95_RS15135 86a5f5870d6c89150475c68a21b19312 214 Pfam PF10090 Histidine phosphotransferase 31 211 1.5E-64 T 06-07-2017 IPR018762 Histidine phosphotransferase CAK95_RS24090 152e7b780858a738c4a0aba91f02cf2f 216 SUPERFAMILY SSF53335 1 179 5.12E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24090 152e7b780858a738c4a0aba91f02cf2f 216 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 192 6.8E-30 T 06-07-2017 CAK95_RS24090 152e7b780858a738c4a0aba91f02cf2f 216 Gene3D G3DSA:3.40.50.150 11 211 3.7E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 SMART SM00911 132 208 8.0E-15 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 Pfam PF07536 HWE histidine kinase 132 207 6.7E-13 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 Gene3D G3DSA:1.20.120.620 19 122 8.6E-4 T 06-07-2017 CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 Pfam PF13493 Domain of unknown function (DUF4118) 23 126 9.6E-8 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 SUPERFAMILY SSF55874 207 307 1.51E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18520 fb6b1f206f1cb731d06c3342180e5a17 318 Gene3D G3DSA:3.30.565.10 187 272 2.9E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS04745 c5ee13f43b8fe1aa943c9360b991b6e2 169 SUPERFAMILY SSF55729 1 148 1.17E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04745 c5ee13f43b8fe1aa943c9360b991b6e2 169 Gene3D G3DSA:3.40.630.30 8 146 7.6E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04745 c5ee13f43b8fe1aa943c9360b991b6e2 169 Pfam PF00583 Acetyltransferase (GNAT) family 52 142 5.7E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 SUPERFAMILY SSF52172 2 118 5.98E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 SUPERFAMILY SSF46894 118 217 6.8E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 SMART SM00862 145 216 1.5E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 SMART SM00448 1 112 2.1E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 Gene3D G3DSA:1.10.10.10 123 218 3.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 Gene3D G3DSA:3.40.50.2300 2 119 1.5E-37 T 06-07-2017 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.7E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS19140 416d96525eebe7bce80db586fe61d8e7 222 Pfam PF00072 Response regulator receiver domain 4 112 4.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 SUPERFAMILY SSF53187 76 345 1.8E-33 T 06-07-2017 CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 Pfam PF16221 winged helix-turn-helix 341 415 1.3E-25 T 06-07-2017 IPR032622 UCP01524, winged helix-turn-helix domain CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 Gene3D G3DSA:3.40.630.10 177 322 4.0E-7 T 06-07-2017 CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 Pfam PF16254 Domain of unknown function (DUF4910) 2 339 6.9E-111 T 06-07-2017 IPR032589 Domain of unknown function DUF4910 CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 PIRSF PIRSF015244 1 417 7.3E-185 T 06-07-2017 IPR012353 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like CAK95_RS10815 a49eb1a5cde1a5f95db061b718038bec 421 Pfam PF09940 Domain of unknown function (DUF2172) 52 143 4.3E-39 T 06-07-2017 IPR032610 Domain of unknown function DUF2172 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 SUPERFAMILY SSF46689 281 332 2.33E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 Gene3D G3DSA:1.10.10.60 236 281 2.9E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 Gene3D G3DSA:1.10.10.60 282 331 2.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 Pfam PF12833 Helix-turn-helix domain 252 329 5.4E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 3.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 3.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 Gene3D G3DSA:3.40.50.880 7 235 8.4E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 282 324 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 SUPERFAMILY SSF46689 230 279 1.61E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 SMART SM00342 245 328 1.1E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 SUPERFAMILY SSF52317 5 211 2.55E-36 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS06290 3e2ab1bce851038db6d6e0ae6006ed5c 348 Pfam PF01965 DJ-1/PfpI family 50 144 7.6E-9 T 06-07-2017 IPR002818 DJ-1/PfpI CAK95_RS17075 e0d10a043fa09dc8b3ec47f93c42def4 338 SUPERFAMILY SSF51556 20 334 5.11E-78 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS17075 e0d10a043fa09dc8b3ec47f93c42def4 338 Pfam PF04909 Amidohydrolase 83 334 1.9E-42 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS17075 e0d10a043fa09dc8b3ec47f93c42def4 338 Gene3D G3DSA:3.20.20.140 20 333 3.9E-85 T 06-07-2017 CAK95_RS17400 663b71ae8b5e891b3fba75ac062cb269 131 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 9 120 2.1E-48 T 06-07-2017 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 CAK95_RS17400 663b71ae8b5e891b3fba75ac062cb269 131 Gene3D G3DSA:3.10.129.10 1 123 4.2E-42 T 06-07-2017 IPR029069 HotDog domain CAK95_RS17400 663b71ae8b5e891b3fba75ac062cb269 131 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 117 1.6E-19 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS17400 663b71ae8b5e891b3fba75ac062cb269 131 Pfam PF03061 Thioesterase superfamily 37 111 3.3E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS17400 663b71ae8b5e891b3fba75ac062cb269 131 SUPERFAMILY SSF54637 2 116 8.82E-30 T 06-07-2017 IPR029069 HotDog domain CAK95_RS03170 fe74b47d2ca6595e03a6a7da508b1528 167 SUPERFAMILY SSF54171 113 165 1.31E-12 T 06-07-2017 IPR016177 DNA-binding domain GO:0003677 CAK95_RS03170 fe74b47d2ca6595e03a6a7da508b1528 167 Pfam PF00847 AP2 domain 114 161 1.5E-6 T 06-07-2017 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 CAK95_RS03170 fe74b47d2ca6595e03a6a7da508b1528 167 Pfam PF13392 HNH endonuclease 59 101 5.5E-16 T 06-07-2017 IPR003615 HNH nuclease CAK95_RS03170 fe74b47d2ca6595e03a6a7da508b1528 167 Gene3D G3DSA:3.30.730.10 115 165 8.1E-6 T 06-07-2017 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 CAK95_RS03170 fe74b47d2ca6595e03a6a7da508b1528 167 SUPERFAMILY SSF54060 11 108 1.88E-23 T 06-07-2017 CAK95_RS19715 c994fb263285c3ab241d5060dd6c96b5 188 Pfam PF01124 MAPEG family 56 178 2.2E-7 T 06-07-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CAK95_RS19715 c994fb263285c3ab241d5060dd6c96b5 188 SUPERFAMILY SSF161084 61 185 9.42E-8 T 06-07-2017 CAK95_RS19715 c994fb263285c3ab241d5060dd6c96b5 188 Gene3D G3DSA:1.20.120.550 66 186 4.3E-5 T 06-07-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 Pfam PF00672 HAMP domain 138 205 3.8E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 Gene3D G3DSA:3.30.565.10 284 411 1.5E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SMART SM00388 210 271 2.3E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SUPERFAMILY SSF47384 193 269 2.35E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SUPERFAMILY SSF158472 157 208 7.06E-8 T 06-07-2017 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 Gene3D G3DSA:1.10.287.130 201 267 1.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SMART SM00304 157 209 1.8E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SUPERFAMILY SSF55874 260 411 2.36E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 Pfam PF00512 His Kinase A (phospho-acceptor) domain 212 269 7.5E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 410 4.8E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28255 a79e322fb042829ec967ab40c58131bf 412 SMART SM00387 307 412 1.9E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26630 226591c788fb48c1b468675b37af25cc 283 Gene3D G3DSA:2.30.260.10 189 275 3.3E-29 T 06-07-2017 IPR023360 Putative xylanase-like C-terminal CAK95_RS26630 226591c788fb48c1b468675b37af25cc 283 Pfam PF07313 Protein of unknown function (DUF1460) 69 266 9.0E-75 T 06-07-2017 IPR010846 Protein of unknown function DUF1460 CAK95_RS26630 226591c788fb48c1b468675b37af25cc 283 SUPERFAMILY SSF54001 40 274 1.01E-75 T 06-07-2017 CAK95_RS26630 226591c788fb48c1b468675b37af25cc 283 Gene3D G3DSA:1.10.3670.10 61 188 2.4E-42 T 06-07-2017 CAK95_RS15675 d1716da7a3b4e3bbc9cb7d0d9606f2a6 210 SUPERFAMILY SSF109604 19 209 1.26E-55 T 06-07-2017 CAK95_RS15675 d1716da7a3b4e3bbc9cb7d0d9606f2a6 210 Gene3D G3DSA:1.10.3210.10 17 209 8.0E-65 T 06-07-2017 IPR006674 HD domain CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 172 1.3E-8 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 Pfam PF12833 Helix-turn-helix domain 251 328 1.0E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 SUPERFAMILY SSF46689 280 331 2.69E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 311 327 8.7E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 311 8.7E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 SMART SM00342 245 327 1.4E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS05110 e676af589f212a1ee9bc1bd2b46ee80b 333 Gene3D G3DSA:1.10.10.60 280 330 2.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SUPERFAMILY SSF47384 584 668 1.9E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Gene3D G3DSA:3.30.565.10 655 826 9.4E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SMART SM00091 467 534 2.3 T 06-07-2017 IPR000014 PAS domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SMART SM00091 339 409 66.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SMART SM00091 224 290 1.9 T 06-07-2017 IPR000014 PAS domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SMART SM00387 714 824 7.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 715 822 4.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SMART SM00388 600 668 1.3E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Pfam PF00512 His Kinase A (phospho-acceptor) domain 603 667 3.0E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Pfam PF12860 PAS fold 473 584 8.9E-15 T 06-07-2017 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Pfam PF12860 PAS fold 345 458 2.2E-11 T 06-07-2017 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SUPERFAMILY SSF55874 657 823 1.15E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 808 821 1.8E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 751 765 1.8E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 784 802 1.8E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SUPERFAMILY SSF55785 215 298 1.1E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Gene3D G3DSA:1.10.287.130 595 654 1.7E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Pfam PF13188 PAS domain 226 254 0.11 T 06-07-2017 IPR000014 PAS domain CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Gene3D G3DSA:3.30.450.20 341 455 2.2E-5 T 06-07-2017 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Gene3D G3DSA:3.30.450.20 472 579 5.6E-11 T 06-07-2017 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 Gene3D G3DSA:3.30.450.20 220 326 3.0E-7 T 06-07-2017 CAK95_RS11030 7a2bed07f3c5734b8cafdcce3ed6fcbe 832 SUPERFAMILY SSF55785 451 568 7.15E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS10650 beb46c7baa9301313de183703ec7768c 132 Pfam PF01042 Endoribonuclease L-PSP 12 128 7.0E-26 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS10650 beb46c7baa9301313de183703ec7768c 132 SUPERFAMILY SSF55298 1 131 1.07E-36 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS10650 beb46c7baa9301313de183703ec7768c 132 Gene3D G3DSA:3.30.1330.40 1 131 6.7E-43 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 SUPERFAMILY SSF46785 4 84 3.73E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 SUPERFAMILY SSF53850 90 297 3.62E-41 T 06-07-2017 CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.7E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 Gene3D G3DSA:3.40.190.10 93 191 2.2E-21 T 06-07-2017 CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 Pfam PF03466 LysR substrate binding domain 90 293 1.5E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS13865 200a03748cd5c81af59cd8a458f2263f 300 Gene3D G3DSA:1.10.10.10 3 84 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 Gene3D G3DSA:1.20.120.530 91 227 2.1E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 SMART SM00345 29 87 1.1E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 2.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 Pfam PF07729 FCD domain 97 220 1.1E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 SMART SM00895 97 221 2.8E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 SUPERFAMILY SSF48008 93 227 2.09E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 Gene3D G3DSA:1.10.10.10 28 88 1.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04985 2e45719d5cc990cbdc524b85c6bfabbb 259 SUPERFAMILY SSF46785 27 91 4.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20990 829cb7656f3ea4c92dc8b003f206ae4f 351 SUPERFAMILY SSF53474 129 293 1.8E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20990 829cb7656f3ea4c92dc8b003f206ae4f 351 Gene3D G3DSA:3.40.50.1820 130 339 1.3E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20990 829cb7656f3ea4c92dc8b003f206ae4f 351 PIRSF PIRSF033909 7 349 2.6E-79 T 06-07-2017 IPR014586 Uncharacterised conserved protein UCP033909 CAK95_RS20990 829cb7656f3ea4c92dc8b003f206ae4f 351 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 128 332 9.7E-59 T 06-07-2017 IPR010297 Protein of unknown function DUF900, hydrolase-like CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 SUPERFAMILY SSF52943 2 293 6.02E-88 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 293 2.5E-102 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 PRINTS PR00126 ATP synthase gamma subunit signature 240 259 1.6E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 PRINTS PR00126 ATP synthase gamma subunit signature 271 292 1.6E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.6E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 1.6E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 PIRSF PIRSF039089 1 293 3.8E-104 T 06-07-2017 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Gene3D G3DSA:3.40.1380.10 75 195 9.0E-34 T 06-07-2017 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Gene3D G3DSA:1.10.287.80 243 288 2.6E-28 T 06-07-2017 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 279 292 - T 06-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Pfam PF00231 ATP synthase 3 293 1.3E-89 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 293 33.097 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Gene3D G3DSA:1.10.287.80 208 242 1.2E-33 T 06-07-2017 CAK95_RS07380 c3ef850cef09fb373eb0f3a25d6b92d1 293 Gene3D G3DSA:1.10.287.80 19 60 1.2E-33 T 06-07-2017 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 PIRSF PIRSF006294 4 534 1.4E-217 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 15 534 2.8E-189 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 Gene3D G3DSA:3.90.228.20 342 532 7.4E-116 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 Gene3D G3DSA:3.90.228.20 218 280 7.4E-116 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 SUPERFAMILY SSF53795 218 534 1.03E-132 T 06-07-2017 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 Gene3D G3DSA:3.40.449.10 23 216 6.5E-67 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 SUPERFAMILY SSF68923 10 217 1.67E-72 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 17 534 53.07 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CAK95_RS06825 de4eb6885e4a884f1690efa3cc15638b 539 Pfam PF01293 Phosphoenolpyruvate carboxykinase 23 485 3.2E-202 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 TIGRFAM TIGR03498 FliI_clade3: flagellar protein export ATPase FliI 18 434 2.6E-199 T 06-07-2017 IPR022426 Flagellum-specific ATP synthase FliI, clade 3 GO:0009288|GO:0016887|GO:0030257|GO:0044781 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 354 1.1E-73 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 Gene3D G3DSA:3.40.50.300 126 402 1.9E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 SMART SM00382 156 339 7.6E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 20 81 3.3E-6 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 SUPERFAMILY SSF52540 91 358 5.32E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 4 434 8.8E-163 T 06-07-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS15225 f443382654f2049331a6d9b21fb33869 441 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 SMART SM00833 254 348 3.1E-16 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 347 2.4E-25 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 181 1.7E-59 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 SUPERFAMILY SSF52540 4 209 7.71E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 Gene3D G3DSA:3.30.1220.10 232 349 1.8E-45 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 Gene3D G3DSA:3.40.50.300 4 201 1.4E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12895 57c5a173e17d939842b0c084a1f7a970 349 SUPERFAMILY SSF90002 255 348 6.67E-28 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 SMART SM00344 2 111 3.0E-35 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 SUPERFAMILY SSF46785 2 62 9.67E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 Gene3D G3DSA:1.10.10.10 6 54 6.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 Gene3D G3DSA:3.30.70.920 55 138 4.4E-26 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 SUPERFAMILY SSF54909 62 150 9.39E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 Pfam PF01037 Lrp/AsnC ligand binding domain 68 142 4.0E-21 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS11765 e4d0779c76fe1b7040cd58319c13e174 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 2.9E-16 T 06-07-2017 CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 8 351 7.6E-164 T 06-07-2017 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 Pfam PF13186 Iron-sulfur cluster-binding domain 242 308 7.8E-11 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 PIRSF PIRSF037420 2 355 4.8E-109 T 06-07-2017 IPR017200 Coenzyme PQQ synthesis protein E CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 SUPERFAMILY SSF102114 11 317 9.29E-66 T 06-07-2017 CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 245 335 1.5E-8 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 Gene3D G3DSA:3.20.20.70 11 326 1.6E-64 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 Pfam PF04055 Radical SAM superfamily 18 170 7.8E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS16075 96104152f47e0ec93790a0cb5a004cc7 368 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 368 167.207 T 06-07-2017 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 CAK95_RS08350 d5b184289bcdda780b24a9b2e4576025 157 SUPERFAMILY SSF158682 21 147 6.15E-26 T 06-07-2017 IPR029024 TerB-like CAK95_RS08350 d5b184289bcdda780b24a9b2e4576025 157 Gene3D G3DSA:1.10.3680.10 19 145 1.1E-19 T 06-07-2017 IPR029024 TerB-like CAK95_RS08350 d5b184289bcdda780b24a9b2e4576025 157 Pfam PF05099 Tellurite resistance protein TerB 17 144 6.0E-37 T 06-07-2017 IPR007791 Co-chaperone DjlA, N-terminal CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 Gene3D G3DSA:3.40.50.150 1 181 5.2E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 Pfam PF03602 Conserved hypothetical protein 95 1 180 1.7E-51 T 06-07-2017 CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 PIRSF PIRSF004553 1 183 6.7E-50 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 SUPERFAMILY SSF53335 1 179 2.86E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13350 bb136f8911895b64e42ac85dc3505c01 183 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 1.1E-40 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS17430 36169c9cdf18b9c596b2cb5323a8849a 270 Pfam PF00005 ABC transporter 20 179 1.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17430 36169c9cdf18b9c596b2cb5323a8849a 270 SMART SM00382 28 227 2.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17430 36169c9cdf18b9c596b2cb5323a8849a 270 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 3.9E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS17430 36169c9cdf18b9c596b2cb5323a8849a 270 Gene3D G3DSA:3.40.50.300 3 251 2.8E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17430 36169c9cdf18b9c596b2cb5323a8849a 270 SUPERFAMILY SSF52540 3 250 3.74E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 Pfam PF01799 [2Fe-2S] binding domain 77 153 3.6E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 SUPERFAMILY SSF54292 4 91 2.49E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 SUPERFAMILY SSF47741 88 159 4.84E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 59 2.7E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 Gene3D G3DSA:3.10.20.30 6 78 2.2E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS16220 7adca2ff531cd6fc182552f2bbc7ec28 165 Gene3D G3DSA:1.10.150.120 79 160 4.9E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Pfam PF00994 Probable molybdopterin binding domain 177 315 8.8E-22 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Gene3D G3DSA:2.170.190.11 46 127 2.2E-27 T 06-07-2017 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Gene3D G3DSA:3.90.105.10 128 161 1.4E-6 T 06-07-2017 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 SUPERFAMILY SSF63882 3 172 7.19E-48 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 SMART SM00852 177 316 3.6E-39 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 SUPERFAMILY SSF53218 174 321 9.16E-40 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 163 7.2E-29 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Gene3D G3DSA:3.40.980.10 162 328 1.2E-52 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Gene3D G3DSA:2.40.340.10 329 398 6.9E-10 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 SUPERFAMILY SSF63867 326 401 8.24E-13 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS23070 e54d00cc22fd5aba5bfd324cc6576bb4 403 Pfam PF03454 MoeA C-terminal region (domain IV) 330 399 1.0E-9 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 311 384 7.5E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 146 203 7.5E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 387 478 1.6E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 635 785 1.6E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 178 721 1.9E-145 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 204 309 3.2E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 SUPERFAMILY SSF56003 149 786 1.83E-176 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 SMART SM01008 26 157 1.3E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.30.365.10 479 616 7.0E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 157 4.5E-22 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 SUPERFAMILY SSF54665 11 179 3.27E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS01405 7828d0753d7baab2fb397542c3541e06 791 Gene3D G3DSA:3.90.1170.50 11 145 8.3E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Gene3D G3DSA:3.40.50.980 202 359 3.1E-32 T 06-07-2017 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Gene3D G3DSA:2.30.38.10 360 428 9.8E-19 T 06-07-2017 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Gene3D G3DSA:3.40.50.980 42 201 3.6E-31 T 06-07-2017 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Gene3D G3DSA:3.30.300.30 433 533 4.3E-31 T 06-07-2017 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 SUPERFAMILY SSF56801 33 534 4.45E-134 T 06-07-2017 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Pfam PF00501 AMP-binding enzyme 55 438 1.6E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS17115 b0bfb6d2ca8cd7e10d4fc9de870165da 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 525 1.7E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 SUPERFAMILY SSF51905 145 310 2.59E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 SUPERFAMILY SSF51905 4 189 1.04E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 SUPERFAMILY SSF55424 312 404 3.94E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 Gene3D G3DSA:3.50.50.60 4 103 2.2E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 301 3.9E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 3.6E-25 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.6E-25 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.6E-25 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.6E-25 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.6E-25 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.1E-13 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.1E-13 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 1.1E-13 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.1E-13 T 06-07-2017 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 Pfam PF14759 Reductase C-terminal 321 402 2.1E-30 T 06-07-2017 IPR028202 Reductase, C-terminal CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 Gene3D G3DSA:3.30.390.30 321 403 1.7E-30 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS00945 988bd6dbaf2615a8ab07dce50574b9b9 423 Gene3D G3DSA:3.50.50.60 104 310 5.5E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 285 360 1.3E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 125 177 1.3E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 SUPERFAMILY SSF56003 128 747 3.93E-159 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 610 747 2.3E-54 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 363 465 2.3E-54 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.90.1170.50 3 124 5.7E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 681 1.1E-149 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 SMART SM01008 21 136 1.2E-50 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 136 1.1E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 178 283 3.7E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 SUPERFAMILY SSF54665 3 136 1.27E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS14260 2989a1bde9ae6b0734465a6b5d4b1ec8 759 Gene3D G3DSA:3.30.365.10 466 609 2.9E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18940 a9e47a651a27951e1ab64d96d9b59a41 161 Gene3D G3DSA:3.30.2020.10 13 97 1.1E-13 T 06-07-2017 IPR018841 Protein of unknown function DUF2442 CAK95_RS18940 a9e47a651a27951e1ab64d96d9b59a41 161 SUPERFAMILY SSF47413 99 153 8.13E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS18940 a9e47a651a27951e1ab64d96d9b59a41 161 Gene3D G3DSA:1.10.260.40 98 153 1.9E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS18940 a9e47a651a27951e1ab64d96d9b59a41 161 SUPERFAMILY SSF143880 13 97 1.44E-10 T 06-07-2017 IPR018841 Protein of unknown function DUF2442 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 Pfam PF11953 Domain of unknown function (DUF3470) 64 103 6.1E-20 T 06-07-2017 IPR022569 Ferredoxin, C-terminal CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 SUPERFAMILY SSF54862 3 106 9.52E-25 T 06-07-2017 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.4E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.4E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.4E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 Gene3D G3DSA:3.30.70.20 3 84 2.7E-20 T 06-07-2017 CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 Pfam PF00037 4Fe-4S binding domain 34 56 1.0E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS10565 a30b0c9b9cf9086eff52c7c130ff3790 111 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 Pfam PF03466 LysR substrate binding domain 93 302 1.4E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 SUPERFAMILY SSF53850 95 305 3.08E-43 T 06-07-2017 CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 Gene3D G3DSA:3.40.190.10 97 182 7.7E-23 T 06-07-2017 CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 Gene3D G3DSA:3.40.190.10 183 266 2.7E-24 T 06-07-2017 CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 SUPERFAMILY SSF46785 9 116 5.71E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12250 0948e8b6dec29837881de171df3e5d5f 307 Gene3D G3DSA:1.10.10.10 10 88 1.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11425 6f06790c964ed7554e6069f05d867922 355 Pfam PF09084 NMT1/THI5 like 45 257 6.1E-21 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS11425 6f06790c964ed7554e6069f05d867922 355 Gene3D G3DSA:3.40.190.10 118 247 1.2E-18 T 06-07-2017 CAK95_RS11425 6f06790c964ed7554e6069f05d867922 355 SUPERFAMILY SSF53850 26 258 1.83E-37 T 06-07-2017 CAK95_RS11425 6f06790c964ed7554e6069f05d867922 355 SMART SM00062 29 253 0.0092 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS21895 33598fc18e8e9a3d2e7b0f30bbb823a8 312 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 131 159 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21895 33598fc18e8e9a3d2e7b0f30bbb823a8 312 Gene3D G3DSA:2.60.130.10 4 290 6.1E-83 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21895 33598fc18e8e9a3d2e7b0f30bbb823a8 312 Pfam PF00775 Dioxygenase 103 273 1.3E-43 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21895 33598fc18e8e9a3d2e7b0f30bbb823a8 312 SUPERFAMILY SSF49482 3 296 2.88E-79 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21895 33598fc18e8e9a3d2e7b0f30bbb823a8 312 Pfam PF04444 Catechol dioxygenase N terminus 22 92 2.1E-20 T 06-07-2017 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 Gene3D G3DSA:3.40.190.10 94 176 9.7E-21 T 06-07-2017 CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 Gene3D G3DSA:1.10.10.10 3 88 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 SUPERFAMILY SSF46785 2 113 8.71E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 Pfam PF03466 LysR substrate binding domain 94 293 1.2E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 SUPERFAMILY SSF53850 94 293 1.58E-39 T 06-07-2017 CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 Gene3D G3DSA:3.40.190.10 177 264 1.5E-18 T 06-07-2017 CAK95_RS07825 5fe2e1f8c6d9df35087d11f02217ec3d 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 6.8E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 420 9.0E-176 T 06-07-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 SUPERFAMILY SSF51230 2 91 3.53E-27 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Gene3D G3DSA:2.40.50.100 2 93 4.5E-29 T 06-07-2017 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 SUPERFAMILY SSF52777 191 420 1.87E-90 T 06-07-2017 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Pfam PF00364 Biotin-requiring enzyme 3 75 1.6E-22 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 191 418 4.6E-83 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Pfam PF02817 e3 binding domain 126 159 6.5E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Gene3D G3DSA:3.30.559.10 182 419 4.0E-94 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 Gene3D G3DSA:4.10.320.10 121 171 4.4E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS07470 f3e785882e41f6822434fad57357e2a3 421 SUPERFAMILY SSF47005 119 163 3.53E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS17410 0e92f44e8bc774fa3cdfe80a7aa717a4 553 Gene3D G3DSA:3.40.309.10 308 512 2.2E-31 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS17410 0e92f44e8bc774fa3cdfe80a7aa717a4 553 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 2 550 2.5E-249 T 06-07-2017 IPR011975 Phenylacetic acid degradation protein PaaN2 CAK95_RS17410 0e92f44e8bc774fa3cdfe80a7aa717a4 553 Pfam PF00171 Aldehyde dehydrogenase family 82 499 5.5E-43 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS17410 0e92f44e8bc774fa3cdfe80a7aa717a4 553 Gene3D G3DSA:3.40.605.10 83 301 4.4E-32 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS17410 0e92f44e8bc774fa3cdfe80a7aa717a4 553 SUPERFAMILY SSF53720 82 528 5.11E-63 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 83 7.6E-21 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 147 14.888 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.2E-13 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.2E-13 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.2E-13 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAK95_RS23910 3d887a4ff5fb8669b3df925fbf5912c6 167 Pfam PF02416 mttA/Hcf106 family 4 41 1.2E-5 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 SUPERFAMILY SSF50331 254 363 1.33E-13 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 SMART SM00382 28 229 1.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 Gene3D G3DSA:2.40.50.140 286 348 5.7E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 SUPERFAMILY SSF52540 4 260 1.86E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 Pfam PF00005 ABC transporter 20 179 1.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 Gene3D G3DSA:3.40.50.300 4 256 1.0E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11580 0ab16ef740a3a8ae9dbc1c82ef169856 371 Pfam PF08402 TOBE domain 284 354 3.0E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK95_RS03850 d43d03790533cb401f236b8cf8ff5300 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 318 2.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03850 d43d03790533cb401f236b8cf8ff5300 325 SUPERFAMILY SSF161098 86 317 1.5E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03850 d43d03790533cb401f236b8cf8ff5300 325 SUPERFAMILY SSF161098 30 56 1.5E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03850 d43d03790533cb401f236b8cf8ff5300 325 Gene3D G3DSA:1.10.3720.10 27 315 1.3E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06755 cd02c00fa7f8df5f80378a773da41e67 174 Pfam PF13975 gag-polyprotein putative aspartyl protease 69 158 6.1E-25 T 06-07-2017 CAK95_RS06755 cd02c00fa7f8df5f80378a773da41e67 174 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 78 89 - T 06-07-2017 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 CAK95_RS06755 cd02c00fa7f8df5f80378a773da41e67 174 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 54 174 5.7E-42 T 06-07-2017 IPR011969 Clan AA aspartic peptidase, C-terminal CAK95_RS06755 cd02c00fa7f8df5f80378a773da41e67 174 SUPERFAMILY SSF50630 57 161 3.15E-17 T 06-07-2017 IPR021109 Aspartic peptidase domain CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Gene3D G3DSA:2.40.50.140 67 128 2.3E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 6.2E-24 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 SUPERFAMILY SSF50104 4 65 7.82E-16 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 2.8E-71 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 2.7E-22 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 SUPERFAMILY SSF50249 67 131 4.11E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 PIRSF PIRSF005901 2 188 2.2E-70 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 45.2 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 SMART SM00841 131 186 2.1E-30 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 SUPERFAMILY SSF50249 130 187 1.37E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 SMART SM01185 69 123 2.1E-25 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Gene3D G3DSA:2.30.30.30 4 65 2.1E-21 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Gene3D G3DSA:2.40.50.140 131 187 7.2E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS04185 2043784e1eebacce3469e40d6194dba4 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 6 62 6.3E-18 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like CAK95_RS22185 ffd93f6a2a8ed15981f6c78f246e1191 192 Pfam PF02525 Flavodoxin-like fold 3 182 8.2E-27 T 06-07-2017 IPR003680 Flavodoxin-like fold CAK95_RS22185 ffd93f6a2a8ed15981f6c78f246e1191 192 SUPERFAMILY SSF52218 1 190 1.54E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS22185 ffd93f6a2a8ed15981f6c78f246e1191 192 Gene3D G3DSA:3.40.50.360 1 190 1.3E-33 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 259 2.8E-59 T 06-07-2017 CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 SUPERFAMILY SSF51735 5 261 7.89E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS28825 b83ce8bb55836a923cb4bd228d3b54e2 262 Gene3D G3DSA:3.40.50.720 5 261 5.1E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 407 1.5E-203 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 SMART SM00382 110 330 3.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 SUPERFAMILY SSF52540 61 395 8.52E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 SUPERFAMILY SSF57716 13 48 1.2E-11 T 06-07-2017 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 111 307 5.7E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Gene3D G3DSA:1.10.8.60 314 414 5.0E-36 T 06-07-2017 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 SMART SM01086 314 409 2.9E-32 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 314 389 9.6E-15 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 412 53.978 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Pfam PF06689 ClpX C4-type zinc finger 13 50 2.7E-20 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Gene3D G3DSA:3.40.50.300 291 308 3.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 Gene3D G3DSA:3.40.50.300 64 252 3.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22710 91946e24e45486cf3edf0f4d861fb12e 424 SMART SM00994 12 51 1.7E-24 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 447 582 1.6E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 151 688 1.0E-152 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 SMART SM01008 28 141 1.5E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 130 167 1.5E-19 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 277 352 1.5E-19 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 355 446 3.7E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 603 755 3.7E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 SUPERFAMILY SSF54665 9 148 4.32E-35 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.90.1170.50 11 129 3.9E-35 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 28 141 4.0E-24 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 Gene3D G3DSA:3.30.365.10 168 274 4.9E-40 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27290 4f8a9e1a08c5574488453ca2dcb550e2 756 SUPERFAMILY SSF56003 133 751 2.22E-174 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 SUPERFAMILY SSF51556 62 361 1.76E-44 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 Gene3D G3DSA:2.30.40.10 8 69 1.7E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 Pfam PF01979 Amidohydrolase family 278 377 2.4E-8 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 SUPERFAMILY SSF51338 364 379 4.11E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 SUPERFAMILY SSF51338 3 62 4.11E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 PIRSF PIRSF039004 2 425 5.2E-136 T 06-07-2017 IPR020043 Amidohydrolase EF0837/AHA3915, putative CAK95_RS00440 4e39cfbc91a34184be94053828caa7b5 425 Gene3D G3DSA:3.20.20.140 70 361 4.1E-86 T 06-07-2017 CAK95_RS28665 7b20f84663eb894602e6e745dbfaa55f 467 SUPERFAMILY SSF51556 81 403 3.86E-83 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS28665 7b20f84663eb894602e6e745dbfaa55f 467 Gene3D G3DSA:3.20.20.140 86 393 3.1E-90 T 06-07-2017 CAK95_RS28665 7b20f84663eb894602e6e745dbfaa55f 467 Gene3D G3DSA:2.30.40.10 43 85 2.8E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS28665 7b20f84663eb894602e6e745dbfaa55f 467 Pfam PF07969 Amidohydrolase family 117 417 1.2E-28 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS28665 7b20f84663eb894602e6e745dbfaa55f 467 SUPERFAMILY SSF51338 47 88 7.31E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22605 95e90f9eefda7c432f4b5389ebff4904 353 SUPERFAMILY SSF88713 216 308 2.22E-33 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS22605 95e90f9eefda7c432f4b5389ebff4904 353 SUPERFAMILY SSF88713 54 133 2.22E-33 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS22605 95e90f9eefda7c432f4b5389ebff4904 353 Pfam PF01522 Polysaccharide deacetylase 91 295 3.1E-27 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS22605 95e90f9eefda7c432f4b5389ebff4904 353 Gene3D G3DSA:3.20.20.370 71 133 2.2E-24 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS22605 95e90f9eefda7c432f4b5389ebff4904 353 Gene3D G3DSA:3.20.20.370 216 298 2.2E-24 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS22650 40040947023bd79e12d2f23d92c53a64 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 32 141 3.9E-11 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS22650 40040947023bd79e12d2f23d92c53a64 149 Gene3D G3DSA:3.10.129.10 15 145 1.8E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS22650 40040947023bd79e12d2f23d92c53a64 149 Pfam PF03061 Thioesterase superfamily 57 130 1.3E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS22650 40040947023bd79e12d2f23d92c53a64 149 SUPERFAMILY SSF54637 26 146 5.48E-26 T 06-07-2017 IPR029069 HotDog domain CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 511 702 1.8E-57 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 Gene3D G3DSA:1.10.287.950 473 677 6.5E-61 T 06-07-2017 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SUPERFAMILY SSF158472 324 370 5.23E-9 T 06-07-2017 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SMART SM00283 458 705 2.2E-92 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SMART SM00304 405 457 0.035 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SMART SM00304 324 377 1.5E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SMART SM01358 43 295 3.2E-22 T 06-07-2017 IPR032255 Helical bimodular sensor domain CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 Pfam PF00672 HAMP domain 305 365 5.1E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS04765 6fbd574145f484206e3e09b73b52f381 760 SUPERFAMILY SSF58104 425 706 1.83E-71 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 Pfam PF01494 FAD binding domain 3 336 7.2E-69 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 Gene3D G3DSA:3.50.50.60 274 312 1.9E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 Gene3D G3DSA:3.50.50.60 2 165 1.9E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 SUPERFAMILY SSF51905 263 348 4.82E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 SUPERFAMILY SSF51905 2 175 4.82E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 Gene3D G3DSA:3.30.9.10 166 269 1.7E-7 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 Gene3D G3DSA:3.30.9.10 324 336 1.7E-7 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 5.7E-34 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 5.7E-34 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 5.7E-34 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 5.7E-34 T 06-07-2017 CAK95_RS10640 9d89e61b7dbe5a084690ded8dc033918 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 5.7E-34 T 06-07-2017 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 1.2E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 371 8.3E-34 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 138 1.7E-45 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 SUPERFAMILY SSF53738 162 263 2.28E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Gene3D G3DSA:3.40.120.10 182 256 5.0E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 7 450 47.335 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 SUPERFAMILY SSF55957 364 450 1.57E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 11 447 6.6E-192 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 382 447 1.6E-14 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.7E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 1.7E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 1.7E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Gene3D G3DSA:3.30.310.50 367 447 1.5E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Gene3D G3DSA:3.40.120.10 257 366 1.0E-35 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 SUPERFAMILY SSF53738 8 187 7.46E-49 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 Gene3D G3DSA:3.40.120.10 8 144 2.6E-47 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS28200 6af9965a1a7bd885e64b876d40891d84 452 SUPERFAMILY SSF53738 264 372 3.73E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 379 543 3.1E-55 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 Gene3D G3DSA:3.20.130.10 360 543 8.6E-71 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 ProSitePatterns PS00163 Fumarate lyases signature. 462 471 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 Pfam PF05681 Fumarate hydratase (Fumerase) 57 331 4.1E-85 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 SUPERFAMILY SSF117457 367 542 2.22E-60 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 Pfam PF05683 Fumarase C-terminus 338 543 5.2E-91 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 80 332 3.1E-32 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAK95_RS18415 367d7e71c8e5533c30dd32a006157ce7 547 PIRSF PIRSF001394 36 547 3.1E-220 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CAK95_RS20760 c08170d3482d2e2be187c378a7b27cd3 332 SUPERFAMILY SSF52151 28 325 8.89E-57 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS20760 c08170d3482d2e2be187c378a7b27cd3 332 Pfam PF01734 Patatin-like phospholipase 33 192 8.1E-27 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS20760 c08170d3482d2e2be187c378a7b27cd3 332 Gene3D G3DSA:3.40.1090.10 22 192 1.4E-12 T 06-07-2017 CAK95_RS19615 7f381f655ae4d41d16d11f290575181b 449 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 254 9.2E-57 T 06-07-2017 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 CAK95_RS19615 7f381f655ae4d41d16d11f290575181b 449 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 3 306 1.6E-69 T 06-07-2017 IPR014150 Conjugal transfer, TrbL CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 PRINTS PR00340 P-II protein signature 83 103 7.3E-42 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 PRINTS PR00340 P-II protein signature 2 17 7.3E-42 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 PRINTS PR00340 P-II protein signature 23 41 7.3E-42 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 PRINTS PR00340 P-II protein signature 52 75 7.3E-42 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 SMART SM00938 4 105 1.6E-64 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 PIRSF PIRSF039144 1 112 1.0E-52 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 9.6E-43 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 SUPERFAMILY SSF54913 1 112 5.08E-44 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS08570 f866e6351faa8bb209166d8b1df6e169 112 Gene3D G3DSA:3.30.70.120 1 112 1.8E-48 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK95_RS02130 fe785b66ee06f104859230d37580d930 411 Pfam PF00296 Luciferase-like monooxygenase 26 349 2.0E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02130 fe785b66ee06f104859230d37580d930 411 Gene3D G3DSA:3.20.20.30 23 282 2.2E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02130 fe785b66ee06f104859230d37580d930 411 Gene3D G3DSA:3.20.20.30 324 387 2.2E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS02130 fe785b66ee06f104859230d37580d930 411 SUPERFAMILY SSF51679 27 387 7.85E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS28835 db0518dcb27c26e27a1251d700eccfe5 271 Pfam PF02515 CoA-transferase family III 53 255 2.0E-48 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS28835 db0518dcb27c26e27a1251d700eccfe5 271 SUPERFAMILY SSF89796 51 262 4.32E-57 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS28835 db0518dcb27c26e27a1251d700eccfe5 271 Gene3D G3DSA:3.40.50.10540 53 254 8.3E-57 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 SMART SM00833 258 373 2.4E-54 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 Gene3D G3DSA:3.30.1220.10 248 373 1.4E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 258 373 3.4E-30 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 Gene3D G3DSA:3.40.50.300 2 229 3.7E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 7.2E-55 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK95_RS21970 f9522b975b29df7e80da158ac6316583 401 SUPERFAMILY SSF52540 3 311 7.33E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 Gene3D G3DSA:3.40.309.10 261 442 1.2E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 Pfam PF00171 Aldehyde dehydrogenase family 16 478 8.1E-144 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 482 2.9E-204 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 Gene3D G3DSA:3.40.605.10 3 260 4.1E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS20100 a2cceb01a29d6f24c4d620ed9b2afdc1 498 SUPERFAMILY SSF53720 2 483 4.58E-152 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 Pfam PF13522 Glutamine amidotransferase domain 34 161 1.9E-40 T 06-07-2017 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 Pfam PF00733 Asparagine synthase 241 618 2.0E-85 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 SUPERFAMILY SSF56235 1 220 8.15E-58 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 Gene3D G3DSA:3.60.20.10 1 222 3.3E-62 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 SUPERFAMILY SSF52402 238 379 8.38E-74 T 06-07-2017 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 SUPERFAMILY SSF52402 474 612 8.38E-74 T 06-07-2017 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 PIRSF PIRSF001589 1 627 7.4E-145 T 06-07-2017 CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 Gene3D G3DSA:3.40.50.620 470 618 2.1E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 Gene3D G3DSA:3.40.50.620 237 375 2.1E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS17745 d0d447c63db60dc82da1b57f89ec532a 630 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 554 2.8E-124 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 306 3.9E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 SUPERFAMILY SSF53686 2 328 1.96E-89 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 Gene3D G3DSA:3.40.50.1100 43 137 8.3E-35 T 06-07-2017 CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 Gene3D G3DSA:3.40.50.1100 157 325 1.5E-62 T 06-07-2017 CAK95_RS24185 d1531b006e796e7d8e28a1f7a4322639 346 Gene3D G3DSA:3.40.50.1100 2 42 1.5E-62 T 06-07-2017 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 238 9.0E-67 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 19 243 1.5E-60 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 114 140 8.4E-42 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 114 8.4E-42 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 18 45 8.4E-42 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 171 199 8.4E-42 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 257 18.445 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK95_RS23905 3c1a9a583a9f3bb3bab5f366c1553f12 269 ProSitePatterns PS01218 TatC family signature. 171 190 - T 06-07-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site CAK95_RS14935 af604cd6c5cc9974ed48613294e5d2bc 204 SUPERFAMILY SSF46689 17 82 2.93E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14935 af604cd6c5cc9974ed48613294e5d2bc 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 9.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14935 af604cd6c5cc9974ed48613294e5d2bc 204 Gene3D G3DSA:1.10.357.10 18 182 1.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS14935 af604cd6c5cc9974ed48613294e5d2bc 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14935 af604cd6c5cc9974ed48613294e5d2bc 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 TIGRFAM TIGR00109 hemH: ferrochelatase 23 348 1.9E-80 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 Pfam PF00762 Ferrochelatase 27 347 6.7E-100 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 SUPERFAMILY SSF53800 24 352 1.32E-95 T 06-07-2017 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 Hamap MF_00323 Ferrochelatase [hemH]. 25 348 35.367 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 Gene3D G3DSA:3.40.50.1400 231 349 1.2E-32 T 06-07-2017 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 ProSitePatterns PS00534 Ferrochelatase signature. 217 236 - T 06-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK95_RS16410 b6e3f99fb816d1c77bb5b13bcfeea61c 352 Gene3D G3DSA:3.40.50.1400 26 230 5.2E-59 T 06-07-2017 CAK95_RS20935 984cd70c488f4916e52038a89df0fe17 336 PIRSF PIRSF017082 3 334 1.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20935 984cd70c488f4916e52038a89df0fe17 336 SUPERFAMILY SSF53850 125 297 6.21E-18 T 06-07-2017 CAK95_RS20935 984cd70c488f4916e52038a89df0fe17 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 330 1.4E-94 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20935 984cd70c488f4916e52038a89df0fe17 336 Gene3D G3DSA:3.40.190.10 139 238 1.7E-4 T 06-07-2017 CAK95_RS05885 477388bf83f8959a6f07ec8cb8bfaf3c 455 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 245 449 4.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05885 477388bf83f8959a6f07ec8cb8bfaf3c 455 Pfam PF12501 Phosphate ATP-binding cassette transporter 8 173 2.0E-22 T 06-07-2017 IPR022182 ABC transporter phosphate permease PstC, N-terminal domain GO:0006817 CAK95_RS05885 477388bf83f8959a6f07ec8cb8bfaf3c 455 SUPERFAMILY SSF161098 181 442 2.22E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05885 477388bf83f8959a6f07ec8cb8bfaf3c 455 Gene3D G3DSA:1.10.3720.10 160 454 4.1E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05885 477388bf83f8959a6f07ec8cb8bfaf3c 455 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 158 450 4.4E-85 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CAK95_RS01610 4edd06b0e1b0b48c3b959d945d2c4397 281 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 267 38.374 T 06-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CAK95_RS01610 4edd06b0e1b0b48c3b959d945d2c4397 281 SUPERFAMILY SSF53335 8 275 5.78E-84 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01610 4edd06b0e1b0b48c3b959d945d2c4397 281 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 32 265 1.1E-73 T 06-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CAK95_RS01610 4edd06b0e1b0b48c3b959d945d2c4397 281 Gene3D G3DSA:3.40.50.150 1 274 1.4E-95 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS05290 5f74d8790e2ac7a8397385eed04e3948 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 1.9E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05290 5f74d8790e2ac7a8397385eed04e3948 337 PIRSF PIRSF017082 5 335 8.8E-62 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05290 5f74d8790e2ac7a8397385eed04e3948 337 SUPERFAMILY SSF53850 123 299 1.77E-9 T 06-07-2017 CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 Pfam PF07702 UTRA domain 123 247 3.3E-19 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 SUPERFAMILY SSF64288 84 249 2.83E-27 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 SMART SM00345 36 95 2.6E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 SUPERFAMILY SSF46785 26 107 6.55E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 Gene3D G3DSA:1.10.10.10 29 91 4.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 Gene3D G3DSA:3.40.1410.10 92 251 2.8E-28 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 SMART SM00866 115 254 3.7E-14 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS27950 efec0215b13a8975b922a16453afcb1c 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 95 8.4E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 PRINTS PR00050 Cold shock protein signature 40 58 7.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 PRINTS PR00050 Cold shock protein signature 4 19 7.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 PRINTS PR00050 Cold shock protein signature 25 34 7.5E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 1.4E-24 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 SMART SM00357 3 69 5.0E-28 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 PIRSF PIRSF002599 1 69 1.6E-22 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 SUPERFAMILY SSF50249 1 67 1.65E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS28075 c512fbc4b23e89edf7c385cb16b07ef5 69 Gene3D G3DSA:2.40.50.140 1 66 4.7E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS08480 b6e5b1554fb0aa367257cb1fabfc2ae1 330 Gene3D G3DSA:3.30.2010.10 57 146 2.8E-35 T 06-07-2017 CAK95_RS08480 b6e5b1554fb0aa367257cb1fabfc2ae1 330 Hamap MF_00188 Protease HtpX [htpX]. 3 277 28.829 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAK95_RS08480 b6e5b1554fb0aa367257cb1fabfc2ae1 330 Pfam PF01435 Peptidase family M48 65 276 2.5E-43 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 SUPERFAMILY SSF53323 14 227 5.1E-23 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 187 2.4E-30 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 222 441 1.3E-49 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 Gene3D G3DSA:3.40.50.970 200 407 1.9E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 SUPERFAMILY SSF52518 209 481 9.12E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 SUPERFAMILY SSF52922 500 603 2.92E-12 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 11 597 5.0E-172 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CAK95_RS21500 f34f72a946436b591280fcf151dbb0f1 613 Gene3D G3DSA:3.40.920.10 12 188 1.1E-20 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS14915 66f8ece423810282dbe391a7cc9bd39b 307 Gene3D G3DSA:3.40.190.10 109 233 5.9E-22 T 06-07-2017 CAK95_RS14915 66f8ece423810282dbe391a7cc9bd39b 307 Pfam PF09084 NMT1/THI5 like 32 249 5.4E-25 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS14915 66f8ece423810282dbe391a7cc9bd39b 307 SUPERFAMILY SSF53850 25 249 2.47E-36 T 06-07-2017 CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 SUPERFAMILY SSF46689 5 87 3.73E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 SUPERFAMILY SSF48498 84 200 2.02E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS00770 81fa5feb23d35c2114eb83c8bd3433f7 202 Gene3D G3DSA:1.10.357.10 6 200 5.3E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS11590 0fef034a91e314ee07b98ace007b9f3f 432 SUPERFAMILY SSF53649 22 427 1.03E-82 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS11590 0fef034a91e314ee07b98ace007b9f3f 432 TIGRFAM TIGR02335 hydr_PhnA: phosphonoacetate hydrolase 22 430 2.5E-168 T 06-07-2017 IPR012710 Phosphonoacetate hydrolase GO:0047400 KEGG: 00440+3.11.1.2 CAK95_RS11590 0fef034a91e314ee07b98ace007b9f3f 432 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 36 378 1.5E-26 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CAK95_RS11590 0fef034a91e314ee07b98ace007b9f3f 432 Gene3D G3DSA:3.40.720.10 21 319 5.5E-55 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 51 59 8.6E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 132 148 8.6E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 96 111 8.6E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 TIGRFAM TIGR00077 lspA: signal peptidase II 8 156 9.0E-32 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 Pfam PF01252 Signal peptidase (SPase) II 16 151 1.0E-30 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS19745 826ab2bcddab34342f18979d233aa4a4 163 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 157 14.538 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS25615 95c61f670e789b0bd9eb92eeeafde770 57 SUPERFAMILY SSF52833 6 52 1.43E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25615 95c61f670e789b0bd9eb92eeeafde770 57 Gene3D G3DSA:3.40.30.10 8 52 2.2E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25615 95c61f670e789b0bd9eb92eeeafde770 57 Pfam PF00255 Glutathione peroxidase 8 52 3.0E-6 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK95_RS24065 6237b5efe7766c6b986b99cb3d3f74b6 241 Pfam PF09601 Protein of unknown function (DUF2459) 46 219 1.2E-39 T 06-07-2017 IPR011727 Conserved hypothetical protein CHP02117 CAK95_RS25850 95184fecc5cfbf646f26ce59b61a28b1 368 SUPERFAMILY SSF109998 91 258 7.85E-26 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK95_RS25850 95184fecc5cfbf646f26ce59b61a28b1 368 Pfam PF13624 SurA N-terminal domain 57 197 8.4E-9 T 06-07-2017 CAK95_RS10545 23c60d5786c5c1cce0bf54fff06e3b81 96 Pfam PF00830 Ribosomal L28 family 3 61 1.9E-23 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS10545 23c60d5786c5c1cce0bf54fff06e3b81 96 Gene3D G3DSA:2.30.170.40 2 76 5.4E-32 T 06-07-2017 CAK95_RS10545 23c60d5786c5c1cce0bf54fff06e3b81 96 SUPERFAMILY SSF143800 1 82 1.2E-27 T 06-07-2017 CAK95_RS10545 23c60d5786c5c1cce0bf54fff06e3b81 96 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 19.767 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS10545 23c60d5786c5c1cce0bf54fff06e3b81 96 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.3E-23 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 Gene3D G3DSA:3.20.20.100 1 320 4.0E-97 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 SUPERFAMILY SSF51430 1 319 3.01E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 143 160 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 Pfam PF00248 Aldo/keto reductase family 16 319 2.9E-71 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 PRINTS PR00069 Aldo-keto reductase signature 48 72 8.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 PRINTS PR00069 Aldo-keto reductase signature 143 160 8.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17890 de4b71630f76f598b436227d50e8e1a4 341 PRINTS PR00069 Aldo-keto reductase signature 112 130 8.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 395 4.3E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Gene3D G3DSA:1.10.540.10 3 121 8.4E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 122 1.4E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 SUPERFAMILY SSF47203 247 407 3.38E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 SUPERFAMILY SSF56645 3 247 4.84E-47 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Gene3D G3DSA:1.20.140.10 241 401 2.8E-33 T 06-07-2017 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 237 1.4E-13 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS27155 40c478df1bf4a0a77ce3528958b3a7f1 414 Gene3D G3DSA:2.40.110.10 130 240 3.5E-24 T 06-07-2017 CAK95_RS16445 4cf7e6554d5abecdb5807daa241d36d3 351 SUPERFAMILY SSF53383 2 349 1.51E-89 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS16445 4cf7e6554d5abecdb5807daa241d36d3 351 Pfam PF01212 Beta-eliminating lyase 3 290 2.2E-58 T 06-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CAK95_RS16445 4cf7e6554d5abecdb5807daa241d36d3 351 Gene3D G3DSA:3.40.640.10 1 250 3.2E-53 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS16445 4cf7e6554d5abecdb5807daa241d36d3 351 Gene3D G3DSA:3.90.1150.10 254 349 4.7E-19 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS16445 4cf7e6554d5abecdb5807daa241d36d3 351 PIRSF PIRSF038940 1 350 9.6E-139 T 06-07-2017 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 CAK95_RS21495 7e48dd218bf2710ce273bf45f29242ca 351 SUPERFAMILY SSF52518 17 271 5.89E-64 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS21495 7e48dd218bf2710ce273bf45f29242ca 351 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 66 214 5.5E-24 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS21495 7e48dd218bf2710ce273bf45f29242ca 351 Gene3D G3DSA:3.40.50.970 29 266 5.1E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS20195 16beadc39c6d9da793f49c68b029e96f 117 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 30 115 2.4E-28 T 06-07-2017 IPR012997 Rare lipoprotein A CAK95_RS20195 16beadc39c6d9da793f49c68b029e96f 117 Gene3D G3DSA:2.40.40.10 63 107 2.4E-6 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS20195 16beadc39c6d9da793f49c68b029e96f 117 Pfam PF03330 Lytic transglycolase 29 111 4.9E-22 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS20195 16beadc39c6d9da793f49c68b029e96f 117 SUPERFAMILY SSF50685 22 107 3.84E-12 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS00245 8264b4f6f30a4dbacc2ef055f626e6aa 438 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 429 2.7E-74 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS00245 8264b4f6f30a4dbacc2ef055f626e6aa 438 PIRSF PIRSF006066 5 438 2.4E-82 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS00245 8264b4f6f30a4dbacc2ef055f626e6aa 438 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 434 1.3E-86 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 SUPERFAMILY SSF46785 22 160 4.08E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 SMART SM00347 46 146 2.9E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 2.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 2.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 2.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 2.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 Pfam PF01047 MarR family 57 110 2.7E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS04565 a0f3bf9b26adbfa3d8e5fc306135fd39 164 Gene3D G3DSA:1.10.10.10 28 160 4.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04700 14a3da845314798b504cbd7c74cb7f1c 265 SMART SM00382 37 234 2.7E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04700 14a3da845314798b504cbd7c74cb7f1c 265 Gene3D G3DSA:3.40.50.300 4 227 3.4E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04700 14a3da845314798b504cbd7c74cb7f1c 265 Pfam PF00005 ABC transporter 29 174 1.9E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04700 14a3da845314798b504cbd7c74cb7f1c 265 SUPERFAMILY SSF52540 6 243 6.48E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27925 abf05a4266022aec6ced6cab2dde5d8d 158 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 16 157 1.2E-48 T 06-07-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAK95_RS27925 abf05a4266022aec6ced6cab2dde5d8d 158 Pfam PF06754 Phosphonate metabolism protein PhnG 16 156 1.1E-51 T 06-07-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Gene3D G3DSA:1.10.540.10 11 101 8.2E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Gene3D G3DSA:1.20.140.10 216 378 3.0E-18 T 06-07-2017 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 SUPERFAMILY SSF56645 13 221 1.22E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 252 357 7.8E-7 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 213 3.4E-8 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Gene3D G3DSA:2.40.110.10 129 215 1.6E-22 T 06-07-2017 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 SUPERFAMILY SSF47203 244 376 3.54E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 101 1.3E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS07760 5bf3bcc35e31efbbb85ad7cbf7139765 382 PIRSF PIRSF016578 1 381 1.3E-36 T 06-07-2017 CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 Pfam PF00563 EAL domain 342 568 5.0E-62 T 06-07-2017 IPR001633 EAL domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 Gene3D G3DSA:3.20.20.450 341 570 1.6E-62 T 06-07-2017 IPR001633 EAL domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 SMART SM00267 150 322 1.6E-36 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 SMART SM00052 334 575 4.8E-50 T 06-07-2017 IPR001633 EAL domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 SUPERFAMILY SSF55073 166 324 1.88E-30 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 Gene3D G3DSA:3.30.70.270 163 330 7.5E-35 T 06-07-2017 CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 160 315 2.7E-24 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 Gene3D G3DSA:3.30.450.20 27 145 5.4E-6 T 06-07-2017 CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 SUPERFAMILY SSF141868 340 570 2.48E-64 T 06-07-2017 IPR001633 EAL domain CAK95_RS10335 46494ee6d5618c58b4179c04ff782c7d 587 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 314 1.6E-27 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 7.3E-7 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 43 157 3.4E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Gene3D G3DSA:2.40.110.10 162 270 1.2E-26 T 06-07-2017 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 467 601 7.6E-34 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 451 2.1E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 SUPERFAMILY SSF47203 288 474 7.41E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Gene3D G3DSA:1.20.140.10 271 459 1.2E-45 T 06-07-2017 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 272 3.3E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 SUPERFAMILY SSF56645 38 280 3.8E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS05615 25bf754ef8ce96c287150fcab30c097e 606 Gene3D G3DSA:1.10.540.10 36 159 1.6E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 Gene3D G3DSA:3.40.50.620 5 230 3.5E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 PIRSF PIRSF006293 3 236 1.3E-69 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 SUPERFAMILY SSF52402 5 230 6.62E-54 T 06-07-2017 CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 223 7.6E-61 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 Pfam PF06508 Queuosine biosynthesis protein QueC 6 230 3.8E-73 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAK95_RS21770 eddfa9120b213bd399a59074056054ae 237 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 235 50.435 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 Gene3D G3DSA:1.10.10.10 10 73 1.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 SUPERFAMILY SSF46785 6 76 4.55E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 Pfam PF07729 FCD domain 82 206 3.3E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 9.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 SUPERFAMILY SSF48008 79 213 8.11E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 SMART SM00895 82 208 8.1E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 SMART SM00345 14 72 5.4E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS08105 8773456deeb75292e800078e162c1f36 224 Gene3D G3DSA:1.20.120.530 75 219 8.6E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 SUPERFAMILY SSF52266 61 163 7.94E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 SUPERFAMILY SSF52266 237 347 7.94E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 Pfam PF04311 Protein of unknown function (DUF459) 215 380 1.7E-35 T 06-07-2017 IPR007407 Protein of unknown function DUF459 CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 Pfam PF04311 Protein of unknown function (DUF459) 67 158 2.9E-13 T 06-07-2017 IPR007407 Protein of unknown function DUF459 CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 Gene3D G3DSA:3.40.50.1110 239 342 2.1E-16 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS16430 cd1b13cc92b6039f266f540d3305af14 521 Gene3D G3DSA:3.40.50.1110 66 168 2.1E-16 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS13590 21d8c16ef5fd4d900729af5dc21df8b2 222 Pfam PF02677 Uncharacterized BCR, COG1636 18 192 3.7E-63 T 06-07-2017 IPR003828 Protein of unknown function DUF208 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 SUPERFAMILY SSF51338 328 373 1.07E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 SUPERFAMILY SSF51338 16 78 1.07E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 Gene3D G3DSA:2.30.40.10 273 365 7.6E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 Hamap MF_01518 Adenine deaminase [ade]. 24 582 31.097 T 06-07-2017 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 Pfam PF01979 Amidohydrolase family 74 358 4.2E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 Pfam PF13382 Adenine deaminase C-terminal domain 414 578 8.0E-41 T 06-07-2017 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 Gene3D G3DSA:2.30.40.10 23 117 2.2E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22485 904d104daeb00187b5008d82e4a8ee8a 588 SUPERFAMILY SSF51556 78 328 1.11E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS21965 da167222b722367f0be6f37c4b6c8cd9 205 Gene3D G3DSA:3.40.30.10 6 87 7.5E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21965 da167222b722367f0be6f37c4b6c8cd9 205 Gene3D G3DSA:1.20.1050.10 88 202 6.6E-16 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS21965 da167222b722367f0be6f37c4b6c8cd9 205 SUPERFAMILY SSF52833 5 84 1.95E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21965 da167222b722367f0be6f37c4b6c8cd9 205 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 74 1.2E-12 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS21965 da167222b722367f0be6f37c4b6c8cd9 205 SUPERFAMILY SSF47616 86 195 6.96E-17 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Gene3D G3DSA:2.40.30.10 321 393 3.9E-35 T 06-07-2017 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Gene3D G3DSA:2.40.30.10 171 207 3.9E-35 T 06-07-2017 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Pfam PF04060 Putative Fe-S cluster 97 127 2.8E-6 T 06-07-2017 IPR007202 4Fe-4S domain GO:0051536 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Gene3D G3DSA:3.40.50.80 394 536 5.1E-57 T 06-07-2017 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 SUPERFAMILY SSF52343 383 537 5.37E-51 T 06-07-2017 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Gene3D G3DSA:1.20.990.10 208 246 8.2E-9 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Pfam PF00175 Oxidoreductase NAD-binding domain 395 501 3.8E-17 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 486 494 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 394 413 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 463 479 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 357 366 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 419 428 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 324 331 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 432 443 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 209 219 4.8E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 Pfam PF00667 FAD binding domain 172 362 1.6E-24 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CAK95_RS17030 aebb82c68348dadd2efe70e0895adf5e 537 SUPERFAMILY SSF63380 171 383 1.11E-51 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS17950 688986d2c06f5a3aa2fa949139c55734 377 SUPERFAMILY SSF53448 39 281 1.03E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17950 688986d2c06f5a3aa2fa949139c55734 377 Gene3D G3DSA:3.90.550.10 45 247 5.9E-13 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17950 688986d2c06f5a3aa2fa949139c55734 377 Pfam PF13506 Glycosyl transferase family 21 104 271 4.5E-50 T 06-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Gene3D G3DSA:3.40.50.300 23 163 3.6E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Pfam PF16193 AAA C-terminal domain 193 268 1.2E-19 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Gene3D G3DSA:1.10.3710.10 350 442 2.1E-30 T 06-07-2017 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Gene3D G3DSA:1.20.272.10 250 348 4.3E-45 T 06-07-2017 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 SUPERFAMILY SSF48019 254 439 2.95E-74 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 64 171 2.3E-15 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 SMART SM00382 59 177 3.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Gene3D G3DSA:1.10.8.60 164 226 8.5E-7 T 06-07-2017 CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 434 1.8E-67 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal CAK95_RS21430 c5e68a210a545325c70ed5f3895f2c48 444 SUPERFAMILY SSF52540 20 229 7.71E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 Gene3D G3DSA:3.40.50.880 288 539 3.1E-96 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 Pfam PF00117 Glutamine amidotransferase class-I 301 535 6.1E-54 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 Hamap MF_01227 CTP synthase [pyrG]. 2 540 49.632 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 Gene3D G3DSA:3.40.50.300 1 284 7.6E-124 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 SUPERFAMILY SSF52540 1 266 3.13E-117 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 Pfam PF06418 CTP synthase N-terminus 3 263 2.8E-118 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 SUPERFAMILY SSF52317 289 539 4.9E-78 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS23125 7649c75c4e2c14b5724c70ccfff136d3 543 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 6.7E-227 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 Gene3D G3DSA:3.40.50.1970 12 182 4.3E-62 T 06-07-2017 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 SUPERFAMILY SSF56796 14 370 1.96E-109 T 06-07-2017 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 22 367 7.5E-107 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 11 372 39.645 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 Pfam PF01761 3-dehydroquinate synthase 77 339 6.0E-97 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 Gene3D G3DSA:1.20.1090.10 183 370 2.5E-62 T 06-07-2017 CAK95_RS10505 bf871286b7384566302296a47d3b23a5 375 PIRSF PIRSF001455 12 374 4.1E-97 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK95_RS15695 ec6bf5e0ad7d00428d96244d9d85b481 207 Gene3D G3DSA:1.10.340.30 11 191 2.0E-79 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS15695 ec6bf5e0ad7d00428d96244d9d85b481 207 Pfam PF03352 Methyladenine glycosylase 15 190 1.4E-77 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CAK95_RS15695 ec6bf5e0ad7d00428d96244d9d85b481 207 SUPERFAMILY SSF48150 11 194 2.9E-78 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS15695 ec6bf5e0ad7d00428d96244d9d85b481 207 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 12 190 7.7E-75 T 06-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CAK95_RS26015 23daa9b0b52d5524c0c3124a6d9d6f90 481 SUPERFAMILY SSF56954 74 457 5.36E-56 T 06-07-2017 CAK95_RS26015 23daa9b0b52d5524c0c3124a6d9d6f90 481 SUPERFAMILY SSF56954 9 28 5.36E-56 T 06-07-2017 CAK95_RS26015 23daa9b0b52d5524c0c3124a6d9d6f90 481 Gene3D G3DSA:1.20.1600.10 145 458 6.3E-29 T 06-07-2017 CAK95_RS26015 23daa9b0b52d5524c0c3124a6d9d6f90 481 Pfam PF02321 Outer membrane efflux protein 281 452 7.3E-13 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Gene3D G3DSA:3.30.300.30 388 490 4.2E-28 T 06-07-2017 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Gene3D G3DSA:2.30.38.10 322 387 5.5E-13 T 06-07-2017 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Pfam PF00501 AMP-binding enzyme 16 393 3.1E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 SUPERFAMILY SSF56801 16 490 9.29E-129 T 06-07-2017 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Gene3D G3DSA:3.40.50.980 162 314 5.7E-38 T 06-07-2017 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Gene3D G3DSA:3.40.50.980 17 161 3.3E-33 T 06-07-2017 CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 Pfam PF13193 AMP-binding enzyme C-terminal domain 403 472 5.1E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS04960 24249a51ed0346371da4d14b14fa616e 494 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 SUPERFAMILY SSF54292 12 105 5.11E-29 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 23 75 5.9E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 Gene3D G3DSA:3.10.20.30 18 91 1.1E-32 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 SUPERFAMILY SSF47741 101 167 1.02E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 Gene3D G3DSA:1.10.150.120 92 166 7.2E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 Pfam PF01799 [2Fe-2S] binding domain 90 162 1.5E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 117 128 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS26210 6aa045771a552d46d3df6554ed8ee79a 169 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 56 64 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 SUPERFAMILY SSF53155 7 85 6.47E-11 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 Gene3D G3DSA:3.30.160.70 7 76 4.5E-5 T 06-07-2017 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 90 155 1.0E-19 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 156 2.2E-19 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 SUPERFAMILY SSF46767 89 150 5.76E-17 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK95_RS09305 be22f89a5b67277d228ec61a86084476 186 Gene3D G3DSA:1.10.10.10 89 150 2.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 Gene3D G3DSA:1.10.287.990 57 126 4.3E-26 T 06-07-2017 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 SUPERFAMILY SSF46609 36 128 4.19E-32 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 202 209 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PRINTS PR01703 Manganese superoxide dismutase signature 163 171 4.4E-24 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PRINTS PR01703 Manganese superoxide dismutase signature 200 212 4.4E-24 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PRINTS PR01703 Manganese superoxide dismutase signature 43 54 4.4E-24 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PRINTS PR01703 Manganese superoxide dismutase signature 64 77 4.4E-24 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PRINTS PR01703 Manganese superoxide dismutase signature 110 123 4.4E-24 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 PIRSF PIRSF000349 15 241 5.8E-77 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 134 234 3.7E-38 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 40 126 3.2E-27 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS23755 d03f2c22356da914a2ac7576407b4161 241 SUPERFAMILY SSF54719 127 240 2.23E-42 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 Pfam PF01614 Bacterial transcriptional regulator 119 237 4.7E-13 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 SUPERFAMILY SSF46785 2 64 1.58E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 Gene3D G3DSA:3.30.450.40 65 235 9.2E-27 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 SUPERFAMILY SSF55781 53 238 5.56E-21 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 Pfam PF01022 Bacterial regulatory protein, arsR family 16 44 1.7E-4 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS16835 c9be5b04c4d2c0873398b654cf5ef7f3 239 Gene3D G3DSA:1.10.10.10 4 64 2.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 Pfam PF00027 Cyclic nucleotide-binding domain 49 135 2.2E-13 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 Gene3D G3DSA:1.10.10.10 165 242 2.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 SMART SM00100 30 148 1.1E-6 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 SUPERFAMILY SSF46785 165 242 1.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 Pfam PF13545 Crp-like helix-turn-helix domain 168 239 1.3E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 SUPERFAMILY SSF51206 29 162 4.58E-24 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS03790 d4d0df0c10ba0aca364ce292fcd87028 246 Gene3D G3DSA:2.60.120.10 28 153 3.0E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS19480 11ef2b396ed429f3ed960f4f202a4e16 70 Gene3D G3DSA:1.10.260.40 2 67 1.6E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS19480 11ef2b396ed429f3ed960f4f202a4e16 70 SMART SM00530 10 65 5.7E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS19480 11ef2b396ed429f3ed960f4f202a4e16 70 SUPERFAMILY SSF47413 3 67 5.91E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS19480 11ef2b396ed429f3ed960f4f202a4e16 70 Pfam PF01381 Helix-turn-helix 11 65 1.5E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS27495 3eb9508f5f120ec267bb8957c68122d7 188 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 112 146 7.8E-13 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS27495 3eb9508f5f120ec267bb8957c68122d7 188 SUPERFAMILY SSF51161 44 163 3.05E-32 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS27495 3eb9508f5f120ec267bb8957c68122d7 188 Gene3D G3DSA:2.160.10.10 82 168 8.9E-30 T 06-07-2017 CAK95_RS27495 3eb9508f5f120ec267bb8957c68122d7 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 120 148 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 56 5.8E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 Gene3D G3DSA:1.10.150.120 77 156 3.3E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 Pfam PF01799 [2Fe-2S] binding domain 75 147 1.8E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 SUPERFAMILY SSF47741 86 155 1.31E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 SUPERFAMILY SSF54292 5 89 1.57E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS00085 e813df6a0860925d343abe87243ad006 160 Gene3D G3DSA:3.10.20.30 4 76 7.6E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS01620 b4c75140cdf9c5b8ceb42116cf4db478 201 SUPERFAMILY SSF47616 71 197 1.97E-11 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01620 b4c75140cdf9c5b8ceb42116cf4db478 201 SUPERFAMILY SSF52833 1 89 1.24E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01620 b4c75140cdf9c5b8ceb42116cf4db478 201 Gene3D G3DSA:1.20.1050.10 93 197 5.1E-4 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01620 b4c75140cdf9c5b8ceb42116cf4db478 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 78 3.6E-16 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS01620 b4c75140cdf9c5b8ceb42116cf4db478 201 Gene3D G3DSA:3.40.30.10 2 92 1.2E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 12 210 1.5E-88 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 Gene3D G3DSA:3.40.470.10 26 214 3.4E-59 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 36 211 2.3E-39 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 SUPERFAMILY SSF52141 24 206 5.23E-51 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 Pfam PF03167 Uracil DNA glycosylase superfamily 50 207 2.9E-37 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 SMART SM00986 50 208 8.5E-36 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS14090 05acf1aa08ae1f2ec9fbb1a64f2d355b 219 SMART SM00987 50 208 8.5E-36 T 06-07-2017 CAK95_RS05275 ba4ab667599e43de097e66840a0688bd 267 Pfam PF02673 Bacitracin resistance protein BacA 7 258 1.9E-74 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK95_RS05275 ba4ab667599e43de097e66840a0688bd 267 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 256 5.1E-69 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK95_RS05275 ba4ab667599e43de097e66840a0688bd 267 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 263 17.252 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 Gene3D G3DSA:3.40.30.10 1 76 1.4E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 SUPERFAMILY SSF52833 1 78 7.61E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 74 1.7E-18 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 195 4.4E-8 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 Gene3D G3DSA:1.20.1050.10 77 197 1.6E-35 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS12770 7f2132867ee44c206c442a0073701b00 230 SUPERFAMILY SSF47616 71 198 9.75E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 5 438 36.4 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Gene3D G3DSA:2.160.10.10 377 444 7.7E-26 T 06-07-2017 CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Gene3D G3DSA:2.160.10.10 322 337 7.7E-26 T 06-07-2017 CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 SUPERFAMILY SSF53448 7 255 2.5E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 303 337 1.5E-5 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 269 301 2.1E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 438 1.0E-142 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Pfam PF12804 MobA-like NTP transferase domain 8 141 1.1E-19 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Gene3D G3DSA:2.160.10.10 246 321 4.0E-15 T 06-07-2017 CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Gene3D G3DSA:3.90.550.10 4 245 1.7E-56 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 SUPERFAMILY SSF51161 253 433 2.46E-45 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 383 415 3.1E-7 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23655 a1b5c15a63cdf37e3cf1f96f681b2eda 451 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 389 417 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 7.9E-32 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 Pfam PF01416 tRNA pseudouridine synthase 9 104 1.1E-9 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 PIRSF PIRSF001430 1 245 3.0E-72 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 9.1E-59 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 Gene3D G3DSA:3.30.70.580 1 106 4.6E-34 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 34.731 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 SUPERFAMILY SSF55120 1 245 5.32E-82 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02825 a42adb44e114c9707bfed7e0ee3d8a41 245 Gene3D G3DSA:3.30.70.660 108 243 2.3E-48 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Pfam PF17092 Penicillin-binding protein OB-like domain 325 448 1.9E-21 T 06-07-2017 IPR031376 Penicillin-binding protein, OB-like domain CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Gene3D G3DSA:1.10.3810.10 60 238 1.3E-67 T 06-07-2017 CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 SUPERFAMILY SSF53955 46 262 7.59E-72 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Pfam PF00912 Transglycosylase 59 236 7.1E-59 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 SUPERFAMILY SSF56601 270 322 2.35E-139 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 SUPERFAMILY SSF56601 218 240 2.35E-139 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 SUPERFAMILY SSF56601 445 799 2.35E-139 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 69 747 3.8E-186 T 06-07-2017 CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Pfam PF00905 Penicillin binding protein transpeptidase domain 450 743 8.1E-42 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Gene3D G3DSA:3.40.710.10 443 796 8.1E-145 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS25060 c291758c76e5080b93da713a75d2b127 826 Gene3D G3DSA:3.40.710.10 239 322 8.1E-145 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 Pfam PF00672 HAMP domain 298 365 1.9E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 534 563 5.3E-5 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 5.3E-5 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 Gene3D G3DSA:1.10.287.950 437 627 1.2E-42 T 06-07-2017 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 SMART SM00304 317 370 3.3E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 SMART SM00283 414 661 2.9E-37 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 SUPERFAMILY SSF158472 317 367 3.4E-7 T 06-07-2017 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 SUPERFAMILY SSF58104 382 660 2.62E-53 T 06-07-2017 CAK95_RS07215 dca098fb784beec34e03b8947a045ae8 667 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 468 660 1.4E-31 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 SUPERFAMILY SSF52540 2 231 4.77E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 243 1.7E-109 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 Pfam PF00005 ABC transporter 17 172 1.3E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 SMART SM00382 26 223 7.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS24995 71b3450c415ed99fd9432e2264f7b5e2 249 Gene3D G3DSA:3.40.50.300 1 243 1.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13665 87214fc20d5341d04ef41510e80ee2a2 302 SUPERFAMILY SSF161098 89 277 1.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS13665 87214fc20d5341d04ef41510e80ee2a2 302 Gene3D G3DSA:1.10.3720.10 88 298 1.7E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS13665 87214fc20d5341d04ef41510e80ee2a2 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 301 5.1E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 295 370 1.1E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 129 185 1.1E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 SUPERFAMILY SSF54665 4 159 4.45E-47 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 465 615 1.8E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 621 772 7.3E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 373 464 7.3E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 172 707 6.9E-157 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.90.1170.50 5 128 2.0E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Gene3D G3DSA:3.30.365.10 186 293 1.3E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 140 7.9E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 SMART SM01008 20 140 2.8E-46 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26650 f2119b6670ec1a69260a70ce3f464380 779 SUPERFAMILY SSF56003 132 773 4.97E-191 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 Gene3D G3DSA:3.40.710.10 6 246 8.5E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 88 105 1.2E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 35 46 1.2E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 128 1.2E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 6 228 7.4E-58 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAK95_RS04720 2820dce421d2f94c197e3cbbcf8fd7db 486 SUPERFAMILY SSF56601 7 246 1.32E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS10805 a8738ecfd619d7d5455cc294a507b054 193 Gene3D G3DSA:2.60.120.10 1 177 5.9E-62 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS10805 a8738ecfd619d7d5455cc294a507b054 193 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 168 6.0E-52 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK95_RS10805 a8738ecfd619d7d5455cc294a507b054 193 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 173 1.8E-55 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK95_RS10805 a8738ecfd619d7d5455cc294a507b054 193 SUPERFAMILY SSF51182 1 175 9.79E-58 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 SUPERFAMILY SSF88946 55 124 4.32E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 62 201 1.4E-17 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 Pfam PF08281 Sigma-70, region 4 150 200 4.7E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 SUPERFAMILY SSF88659 143 202 1.94E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 Gene3D G3DSA:1.10.1740.10 55 122 2.6E-15 T 06-07-2017 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 Pfam PF04542 Sigma-70 region 2 63 120 1.8E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15400 92cb0c70bab9bd617d4661b407e27ba5 225 Gene3D G3DSA:1.10.10.10 144 202 1.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04390 ef3cd30fb8fb6434c9bd1210b7337aba 390 SUPERFAMILY SSF53822 24 388 2.53E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS04390 ef3cd30fb8fb6434c9bd1210b7337aba 390 Pfam PF13458 Periplasmic binding protein 24 359 3.2E-69 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS04390 ef3cd30fb8fb6434c9bd1210b7337aba 390 Gene3D G3DSA:3.40.50.2300 19 147 7.2E-43 T 06-07-2017 CAK95_RS04390 ef3cd30fb8fb6434c9bd1210b7337aba 390 Gene3D G3DSA:3.40.50.2300 282 347 7.2E-43 T 06-07-2017 CAK95_RS23710 61e2e5e1da8236243137341fe8781102 267 SUPERFAMILY SSF161098 72 256 6.15E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23710 61e2e5e1da8236243137341fe8781102 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 25 266 2.7E-90 T 06-07-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CAK95_RS23710 61e2e5e1da8236243137341fe8781102 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 266 9.7E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23710 61e2e5e1da8236243137341fe8781102 267 Gene3D G3DSA:1.10.3720.10 70 266 2.1E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08225 9f86054d54e46d2f121cf7f20784dcc0 602 SUPERFAMILY SSF52016 387 584 3.45E-46 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS08225 9f86054d54e46d2f121cf7f20784dcc0 602 SUPERFAMILY SSF143975 10 385 6.02E-118 T 06-07-2017 CAK95_RS08225 9f86054d54e46d2f121cf7f20784dcc0 602 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 133 143 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS08225 9f86054d54e46d2f121cf7f20784dcc0 602 Pfam PF00920 Dehydratase family 50 580 4.1E-155 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS08310 3e733c0f8c3f00b40805268c25aabe35 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 263 4.4E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08310 3e733c0f8c3f00b40805268c25aabe35 275 SUPERFAMILY SSF161098 66 253 7.98E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08310 3e733c0f8c3f00b40805268c25aabe35 275 Gene3D G3DSA:1.10.3720.10 56 256 4.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01800 8de41892e0277fc311d4e7ff04212bc3 329 SUPERFAMILY SSF53850 130 295 2.53E-6 T 06-07-2017 CAK95_RS01800 8de41892e0277fc311d4e7ff04212bc3 329 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 295 1.0E-40 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS13765 e59c50a5aaaf0086addec0d4e14dd29b 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 313 5.3E-50 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS05000 b4930c38daa7047c13185786f4aca262 326 Pfam PF09084 NMT1/THI5 like 48 247 8.3E-20 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS05000 b4930c38daa7047c13185786f4aca262 326 SUPERFAMILY SSF53850 25 309 1.77E-32 T 06-07-2017 CAK95_RS05000 b4930c38daa7047c13185786f4aca262 326 Gene3D G3DSA:3.40.190.10 110 239 3.4E-16 T 06-07-2017 CAK95_RS14960 6feed1606db56979803501b6732cfb2f 240 Pfam PF00005 ABC transporter 20 165 1.5E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14960 6feed1606db56979803501b6732cfb2f 240 SUPERFAMILY SSF52540 3 236 1.49E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14960 6feed1606db56979803501b6732cfb2f 240 SMART SM00382 29 214 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14960 6feed1606db56979803501b6732cfb2f 240 Gene3D G3DSA:3.40.50.300 2 234 3.7E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14960 6feed1606db56979803501b6732cfb2f 240 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS26925 f6a30e6f18556e16703543003ce37ddc 281 Gene3D G3DSA:3.40.50.150 65 227 3.8E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26925 f6a30e6f18556e16703543003ce37ddc 281 Pfam PF13578 Methyltransferase domain 77 173 2.4E-10 T 06-07-2017 CAK95_RS26925 f6a30e6f18556e16703543003ce37ddc 281 SUPERFAMILY SSF53335 46 177 6.34E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 92 501 4.0E-74 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 SUPERFAMILY SSF53850 385 586 1.21E-118 T 06-07-2017 CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 SUPERFAMILY SSF53850 42 351 1.21E-118 T 06-07-2017 CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 PIRSF PIRSF002741 4 588 5.0E-98 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 Gene3D G3DSA:3.10.105.10 302 556 3.7E-45 T 06-07-2017 CAK95_RS23605 d85350d7185bdb095bec3038d963fb4e 591 Gene3D G3DSA:3.90.76.10 56 209 2.6E-32 T 06-07-2017 CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 366 7.4E-125 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 Pfam PF00005 ABC transporter 34 175 1.9E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 Gene3D G3DSA:3.40.50.300 12 251 6.7E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 SUPERFAMILY SSF50331 250 370 2.67E-19 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 SUPERFAMILY SSF52540 18 256 2.8E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 Pfam PF08402 TOBE domain 291 370 2.9E-15 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK95_RS03855 cd95ab80ab1368ff3dca926d62329722 373 SMART SM00382 42 233 1.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12385 cb5813d05c2b7b6f8b5371dc8c1f45e6 251 Hamap MF_00943 Maleate isomerase [maiA]. 5 251 49.646 T 06-07-2017 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 CAK95_RS12385 cb5813d05c2b7b6f8b5371dc8c1f45e6 251 PIRSF PIRSF015736 1 251 1.9E-68 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 496 9.4E-130 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 Pfam PF07690 Major Facilitator Superfamily 25 415 1.7E-55 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 Gene3D G3DSA:1.20.1250.20 477 504 2.7E-14 T 06-07-2017 CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 Gene3D G3DSA:1.20.1250.20 269 426 2.7E-14 T 06-07-2017 CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 Gene3D G3DSA:1.20.1250.20 17 199 1.1E-35 T 06-07-2017 CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 SUPERFAMILY SSF103473 476 505 3.79E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 SUPERFAMILY SSF103473 11 205 3.79E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS10230 53c85ae6f4f3768c060401127176bb05 516 SUPERFAMILY SSF103473 254 425 3.79E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 SUPERFAMILY SSF52540 5 306 1.86E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 SUPERFAMILY SSF52540 364 439 1.86E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 Gene3D G3DSA:3.40.50.300 379 439 1.4E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 Gene3D G3DSA:3.40.50.300 186 290 1.4E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 Pfam PF13604 AAA domain 24 246 2.6E-20 T 06-07-2017 CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 Gene3D G3DSA:3.40.50.300 27 131 1.2E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03035 27e13761b906ae21358757e584a5ed4d 440 Pfam PF13538 UvrD-like helicase C-terminal domain 390 438 1.0E-15 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 Gene3D G3DSA:3.40.50.1370 11 151 2.1E-48 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 14 310 2.4E-91 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 13 313 40.041 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 Gene3D G3DSA:3.40.50.1370 152 290 1.5E-50 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 164 309 5.8E-24 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 88 97 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 143 160 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 227 236 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 292 306 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 50 72 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 268 273 3.8E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 SUPERFAMILY SSF53671 11 313 5.76E-97 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 276 299 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 144 155 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK95_RS22090 2b01886efaaf9b4f67ee0e01a33ac8bd 317 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 156 2.1E-38 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 SUPERFAMILY SSF53335 169 400 8.96E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 Gene3D G3DSA:3.40.50.150 177 398 8.1E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 Pfam PF01555 DNA methylase 203 391 8.1E-14 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 376 396 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 200 214 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 353 371 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 334 351 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 Pfam PF02195 ParB-like nuclease domain 22 104 3.0E-13 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 Gene3D G3DSA:3.90.1530.10 17 105 3.6E-18 T 06-07-2017 CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 PIRSF PIRSF036758 16 414 2.0E-99 T 06-07-2017 IPR015840 DNA methyase, ParB domain-containing CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 SMART SM00470 19 105 4.3E-15 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03655 31125e866bd5fb3b0096c5c45ccce246 457 SUPERFAMILY SSF110849 17 126 1.92E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS15835 28c328df1c92abfa5f034713df3b3394 329 Gene3D G3DSA:1.20.58.340 253 329 3.4E-27 T 06-07-2017 CAK95_RS15835 28c328df1c92abfa5f034713df3b3394 329 Gene3D G3DSA:1.20.58.340 136 182 3.7E-4 T 06-07-2017 CAK95_RS15835 28c328df1c92abfa5f034713df3b3394 329 SUPERFAMILY SSF143865 1 268 1.7E-34 T 06-07-2017 CAK95_RS15835 28c328df1c92abfa5f034713df3b3394 329 Pfam PF01544 CorA-like Mg2+ transporter protein 30 325 1.4E-47 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAK95_RS15835 28c328df1c92abfa5f034713df3b3394 329 SUPERFAMILY SSF144083 264 327 2.09E-20 T 06-07-2017 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 PRINTS PR01549 Autoinducer synthesis protein signature 97 109 6.3E-11 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 PRINTS PR01549 Autoinducer synthesis protein signature 21 40 6.3E-11 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 PRINTS PR01549 Autoinducer synthesis protein signature 42 64 6.3E-11 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 PRINTS PR01549 Autoinducer synthesis protein signature 65 83 6.3E-11 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 Gene3D G3DSA:3.40.630.30 4 200 1.4E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 Pfam PF00765 Autoinducer synthase 15 183 6.3E-19 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS24635 3d17ebb02250bcc3695bff547b4ad077 219 SUPERFAMILY SSF55729 4 198 1.39E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 SUPERFAMILY SSF53850 23 327 4.76E-92 T 06-07-2017 CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 Pfam PF13531 Bacterial extracellular solute-binding protein 41 280 1.6E-48 T 06-07-2017 CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 17 326 9.7E-151 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 146 154 - T 06-07-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 Gene3D G3DSA:3.40.190.10 174 295 8.9E-29 T 06-07-2017 CAK95_RS14695 d74b3b81eda977e3f1e2b986566872d8 329 Gene3D G3DSA:3.40.190.10 22 169 4.0E-50 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 573 32.879 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Gene3D G3DSA:2.40.50.140 4 107 1.3E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 SUPERFAMILY SSF50249 4 107 8.76E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 592 3.1E-180 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 567 6.6E-90 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 4.2E-17 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 SUPERFAMILY SSF55681 113 298 1.27E-92 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 SUPERFAMILY SSF55681 428 593 1.27E-92 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Gene3D G3DSA:3.30.1360.30 283 417 4.0E-46 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Pfam PF02938 GAD domain 314 405 5.0E-7 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 SUPERFAMILY SSF55261 295 423 1.21E-31 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Gene3D G3DSA:3.30.930.10 418 593 4.8E-96 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 Gene3D G3DSA:3.30.930.10 136 282 4.8E-96 T 06-07-2017 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 6.5E-20 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 528 542 6.5E-20 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 484 500 6.5E-20 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25685 8ee7b9fe1d6b11b09ad9a4f8fc951ece 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 6.5E-20 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25335 435d678dfa7d756c18d9bffc60fe700e 397 SUPERFAMILY SSF50182 194 259 2.19E-13 T 06-07-2017 IPR010920 LSM domain CAK95_RS25335 435d678dfa7d756c18d9bffc60fe700e 397 Pfam PF00924 Mechanosensitive ion channel 152 346 2.9E-29 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAK95_RS25335 435d678dfa7d756c18d9bffc60fe700e 397 Gene3D G3DSA:2.30.30.60 209 258 1.7E-6 T 06-07-2017 CAK95_RS16590 573c37e1174b170119aa61dd34eb6d80 150 Pfam PF01638 HxlR-like helix-turn-helix 20 105 9.7E-21 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS16590 573c37e1174b170119aa61dd34eb6d80 150 SUPERFAMILY SSF46785 6 133 1.0E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16590 573c37e1174b170119aa61dd34eb6d80 150 Gene3D G3DSA:1.10.10.10 2 111 6.8E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 Pfam PF00664 ABC transporter transmembrane region 17 265 1.1E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 SUPERFAMILY SSF90123 4 299 6.02E-44 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 Gene3D G3DSA:1.20.1560.10 5 306 2.1E-39 T 06-07-2017 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 SUPERFAMILY SSF52540 307 543 1.36E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 4 544 2.6E-231 T 06-07-2017 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 Pfam PF00005 ABC transporter 337 483 3.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 SMART SM00382 344 531 6.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07860 8cb4b7565392ad2ce6c1de03fa5f612c 595 Gene3D G3DSA:3.40.50.300 318 544 4.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19500 dd16294e80fa0d5f81f7a40c9248ff27 93 Pfam PF12728 Helix-turn-helix domain 18 68 8.4E-7 T 06-07-2017 CAK95_RS19500 dd16294e80fa0d5f81f7a40c9248ff27 93 SUPERFAMILY SSF46955 17 72 3.11E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS19500 dd16294e80fa0d5f81f7a40c9248ff27 93 Gene3D G3DSA:1.10.10.10 18 71 1.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 Gene3D G3DSA:3.40.50.720 1 258 8.7E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 SUPERFAMILY SSF51735 3 259 2.32E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 Pfam PF00106 short chain dehydrogenase 5 198 2.1E-57 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28425 6c6a204e6fda7fb3572b6d0fe1329079 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 260 8.5E-107 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 06-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 1.5E-96 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 7.0E-42 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 42.004 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 SUPERFAMILY SSF55831 1 264 1.05E-129 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 Pfam PF00303 Thymidylate synthase 2 264 3.4E-125 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 5.3E-50 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 5.3E-50 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 5.3E-50 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 5.3E-50 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 5.3E-50 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS14605 0683cf269bd6502d6e0882161fb9a4b5 264 Gene3D G3DSA:3.30.572.10 1 264 6.3E-135 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.1E-4 T 06-07-2017 CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 3.4E-63 T 06-07-2017 CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 SUPERFAMILY SSF51735 6 245 5.92E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28270 6b9f8f66d30d4c241227c7af1c7b472a 246 Gene3D G3DSA:3.40.50.720 5 245 3.0E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20080 29a92c76ec3b92d892a2e25fa83e6726 297 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 9.3E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK95_RS20080 29a92c76ec3b92d892a2e25fa83e6726 297 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 210 245 6.9E-12 T 06-07-2017 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal CAK95_RS20080 29a92c76ec3b92d892a2e25fa83e6726 297 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 SUPERFAMILY SSF52540 3 193 5.6E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 SMART SM00382 306 478 1.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 SMART SM00382 29 192 2.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 SUPERFAMILY SSF52540 276 482 3.45E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 ProSitePatterns PS00211 ABC transporters family signature. 119 133 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 Pfam PF16326 ABC transporter C-terminal domain 526 594 8.7E-16 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 Gene3D G3DSA:3.40.50.300 281 501 3.8E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 Gene3D G3DSA:3.40.50.300 3 214 4.5E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 Pfam PF00005 ABC transporter 20 147 9.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05595 05f66b59bb7b675a74303ef811f1e4fa 603 Pfam PF00005 ABC transporter 299 432 2.1E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 SUPERFAMILY SSF52518 2 181 2.03E-66 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Gene3D G3DSA:3.40.50.970 3 179 2.0E-78 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 SUPERFAMILY SSF52467 188 362 4.43E-65 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Gene3D G3DSA:3.40.50.970 358 559 5.7E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 330 8.1E-43 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 5 568 2.2E-247 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 169 2.1E-60 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 544 3.4E-49 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 Gene3D G3DSA:3.40.50.1220 189 357 1.4E-62 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS14675 ac37d1266e617fe79c6bfb8206fa303e 586 SUPERFAMILY SSF52518 373 567 6.61E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12880 985f0cc69854514d1ecb90e3339faba2 244 SUPERFAMILY SSF52540 5 213 2.56E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12880 985f0cc69854514d1ecb90e3339faba2 244 Pfam PF00005 ABC transporter 21 162 2.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12880 985f0cc69854514d1ecb90e3339faba2 244 Gene3D G3DSA:3.40.50.300 4 233 1.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12880 985f0cc69854514d1ecb90e3339faba2 244 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12880 985f0cc69854514d1ecb90e3339faba2 244 SMART SM00382 29 210 8.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 Gene3D G3DSA:3.20.10.10 134 286 1.1E-46 T 06-07-2017 CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 SUPERFAMILY SSF56752 9 288 2.22E-86 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 Pfam PF01063 Amino-transferase class IV 39 266 5.7E-48 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 14 289 1.3E-82 T 06-07-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 ProSitePatterns PS00770 Aminotransferases class-IV signature. 193 221 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK95_RS01650 e8b6b2221d188679a87628dccb4d81d1 295 Gene3D G3DSA:3.30.470.10 12 127 6.7E-37 T 06-07-2017 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 360 440 8.8E-34 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 158 4.9E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 183 347 8.9E-25 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Hamap MF_00195 GTPase Der [der]. 2 443 37.162 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 SUPERFAMILY SSF52540 3 163 1.03E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 3.2E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Gene3D G3DSA:3.40.50.300 182 365 3.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Gene3D G3DSA:3.40.50.300 3 171 4.9E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 SMART SM00382 182 362 0.06 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 SMART SM00382 1 142 8.0 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 PIRSF PIRSF006485 1 448 4.9E-161 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Pfam PF01926 50S ribosome-binding GTPase 185 303 1.3E-21 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Pfam PF01926 50S ribosome-binding GTPase 5 120 8.3E-26 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 440 5.9E-166 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 SUPERFAMILY SSF52540 138 446 3.68E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26035 84f38913a3fe10c8e5dba190d4076e28 450 Gene3D G3DSA:3.30.300.20 366 443 3.2E-34 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS01360 8839a90814894ec675b871c0c6a2ac0f 291 Hamap MF_00697 UPF0276 protein . 16 289 44.755 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAK95_RS01360 8839a90814894ec675b871c0c6a2ac0f 291 SUPERFAMILY SSF51658 35 273 2.43E-8 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS01360 8839a90814894ec675b871c0c6a2ac0f 291 Pfam PF05114 Protein of unknown function (DUF692) 16 280 3.5E-105 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAK95_RS01360 8839a90814894ec675b871c0c6a2ac0f 291 Gene3D G3DSA:3.20.20.150 14 281 2.5E-100 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS09535 452c2c2a4c2d4b535751363db8cb2693 140 Gene3D G3DSA:3.10.180.10 10 135 3.1E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS09535 452c2c2a4c2d4b535751363db8cb2693 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 131 8.2E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS09535 452c2c2a4c2d4b535751363db8cb2693 140 SUPERFAMILY SSF54593 10 134 1.61E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 Gene3D G3DSA:2.30.30.30 115 176 9.2E-31 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 7.5E-21 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 7.5E-21 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 7.5E-21 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 SUPERFAMILY SSF82679 3 112 5.49E-38 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 Pfam PF02357 Transcription termination factor nusG 3 106 6.9E-26 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 SUPERFAMILY SSF50104 120 176 2.17E-19 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 8.9E-69 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 SMART SM00739 122 149 4.1E-6 T 06-07-2017 IPR005824 KOW CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 25.144 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 Gene3D G3DSA:3.30.70.940 3 112 8.3E-42 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 SMART SM00738 2 110 9.9E-47 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS21170 aa0f34c8818a1a081de08bbbbf072216 176 Pfam PF00467 KOW motif 125 155 1.5E-7 T 06-07-2017 IPR005824 KOW CAK95_RS09235 b801edca1b985453e79159206547b013 161 Gene3D G3DSA:3.40.630.30 15 160 1.7E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS09235 b801edca1b985453e79159206547b013 161 Pfam PF00583 Acetyltransferase (GNAT) family 63 133 1.0E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS09235 b801edca1b985453e79159206547b013 161 SUPERFAMILY SSF55729 15 160 6.75E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS09235 b801edca1b985453e79159206547b013 161 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 24 147 1.1E-25 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Gene3D G3DSA:3.40.50.620 219 392 7.2E-62 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Gene3D G3DSA:3.30.300.10 397 521 3.8E-51 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 11 199 4.1E-67 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 SUPERFAMILY SSF54810 401 521 7.98E-50 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 6.4E-6 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 6.4E-6 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 6.4E-6 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Pfam PF00117 Glutamine amidotransferase class-I 12 196 8.2E-37 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 SUPERFAMILY SSF52402 193 414 1.41E-60 T 06-07-2017 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Pfam PF00958 GMP synthase C terminal domain 429 520 1.8E-43 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 521 53.535 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Pfam PF02540 NAD synthase 215 250 1.7E-5 T 06-07-2017 IPR022310 NAD/GMP synthase CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 Gene3D G3DSA:3.40.50.880 6 218 2.9E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 521 8.3E-147 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK95_RS26275 4e89808bb79502b2764bc4f2ef078dec 521 SUPERFAMILY SSF52317 7 233 1.7E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 11 503 1.2E-211 T 06-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 Pfam PF00682 HMGL-like 12 280 2.1E-96 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 SMART SM00917 376 506 1.4E-38 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 9 515 42.668 T 06-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 206 219 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 Gene3D G3DSA:3.20.20.70 3 354 1.2E-148 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 SUPERFAMILY SSF110921 399 505 1.31E-24 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 505 2.7E-37 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 SUPERFAMILY SSF51569 8 298 6.23E-100 T 06-07-2017 CAK95_RS14800 dcb739f685471bcebf6d684b283fff76 519 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK95_RS13595 116d9def6c86c23934045678d6965df4 287 SUPERFAMILY SSF81345 4 264 1.15E-44 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS13595 116d9def6c86c23934045678d6965df4 287 Gene3D G3DSA:1.10.3470.10 57 263 2.9E-11 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS13595 116d9def6c86c23934045678d6965df4 287 Pfam PF00950 ABC 3 transport family 14 268 1.9E-93 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAK95_RS10595 3d888e11ea42b0cab1065ef94e0dcaaa 295 Pfam PF00565 Staphylococcal nuclease homologue 109 191 3.1E-5 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS10595 3d888e11ea42b0cab1065ef94e0dcaaa 295 Gene3D G3DSA:2.40.50.90 94 194 1.7E-7 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS10595 3d888e11ea42b0cab1065ef94e0dcaaa 295 SUPERFAMILY SSF50199 75 194 8.5E-14 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS02070 c9d83d39ed13733fb9659fce6097ecc8 384 Pfam PF13578 Methyltransferase domain 43 145 1.7E-6 T 06-07-2017 CAK95_RS02070 c9d83d39ed13733fb9659fce6097ecc8 384 Gene3D G3DSA:3.40.50.150 38 114 1.6E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02070 c9d83d39ed13733fb9659fce6097ecc8 384 SUPERFAMILY SSF53335 23 136 5.54E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 SUPERFAMILY SSF52540 2 216 6.41E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 Pfam PF00005 ABC transporter 2 149 5.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 196 218 2.6E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 SMART SM00382 2 196 1.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 Gene3D G3DSA:3.40.50.300 2 215 3.3E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01030 f1b699d4b131d938e5e9758fb488848e 223 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS22630 471b1ca8620cb894c93d4f694a927239 59 Gene3D G3DSA:3.30.1220.10 1 40 2.8E-5 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS22630 471b1ca8620cb894c93d4f694a927239 59 SUPERFAMILY SSF90002 2 40 7.98E-5 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 Pfam PF02049 Flagellar hook-basal body complex protein FliE 55 136 5.8E-23 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 38 136 15.809 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 62 135 2.7E-13 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 67 83 2.5E-6 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 100 116 2.5E-6 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS18285 f0c988c19f3d5655954bbcf75972f3a5 136 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 121 134 2.5E-6 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAK95_RS01765 c4242a9f6dfbcf52a0154ddca486ab20 301 Pfam PF08478 POTRA domain, FtsQ-type 82 150 7.6E-18 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type CAK95_RS01765 c4242a9f6dfbcf52a0154ddca486ab20 301 Pfam PF03799 Cell division protein FtsQ 154 267 3.3E-17 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB CAK95_RS01765 c4242a9f6dfbcf52a0154ddca486ab20 301 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 52 285 22.225 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 Gene3D G3DSA:2.30.40.10 8 78 4.1E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 Pfam PF01979 Amidohydrolase family 60 428 7.1E-22 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 Gene3D G3DSA:3.20.20.140 79 413 6.9E-90 T 06-07-2017 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 SUPERFAMILY SSF51556 64 377 1.25E-91 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 Hamap MF_00220_B Dihydroorotase [pyrC]. 7 433 35.412 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 SUPERFAMILY SSF51338 375 431 4.6E-26 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 SUPERFAMILY SSF51338 8 63 4.6E-26 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS22085 1cefb1501c19fc7e3cf954760ef7b534 435 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 42 432 4.2E-107 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 SMART SM01008 42 160 6.7E-48 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 494 652 6.4E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 SUPERFAMILY SSF56003 153 791 5.23E-187 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 178 726 5.7E-155 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 SUPERFAMILY SSF54665 24 182 3.14E-44 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 653 790 9.6E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 393 491 9.6E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.90.1170.50 27 148 1.9E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 206 312 2.7E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 42 159 1.5E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 149 205 7.6E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26345 4fa6090e1c4d2e27313bd49133d79e59 797 Gene3D G3DSA:3.30.365.10 314 390 7.6E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15490 0c643d41832cd51eaef80d7558e61247 380 Gene3D G3DSA:2.40.50.100 58 91 1.7E-20 T 06-07-2017 CAK95_RS15490 0c643d41832cd51eaef80d7558e61247 380 Gene3D G3DSA:2.40.50.100 166 200 1.7E-20 T 06-07-2017 CAK95_RS15490 0c643d41832cd51eaef80d7558e61247 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 359 9.5E-72 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS15490 0c643d41832cd51eaef80d7558e61247 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 278 4.6E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS15490 0c643d41832cd51eaef80d7558e61247 380 SUPERFAMILY SSF111369 49 283 8.11E-56 T 06-07-2017 CAK95_RS20635 e7aaf26e196a5642b64edaee6d47b85e 198 Pfam PF00775 Dioxygenase 52 196 1.5E-20 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS20635 e7aaf26e196a5642b64edaee6d47b85e 198 SUPERFAMILY SSF49482 45 196 5.23E-48 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS20635 e7aaf26e196a5642b64edaee6d47b85e 198 Gene3D G3DSA:2.60.130.10 40 197 1.7E-46 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21625 870f8317d376115c349a86ad5b7d3fce 133 SUPERFAMILY SSF51182 44 128 9.77E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS21625 870f8317d376115c349a86ad5b7d3fce 133 Pfam PF07883 Cupin domain 51 120 7.6E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS21625 870f8317d376115c349a86ad5b7d3fce 133 Gene3D G3DSA:2.60.120.10 44 130 9.8E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 415 1.7E-29 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 217 6.2E-50 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 SUPERFAMILY SSF142019 3 240 1.31E-83 T 06-07-2017 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 SUPERFAMILY SSF142984 241 326 3.92E-25 T 06-07-2017 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 344 355 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 8 417 2.2E-196 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 SMART SM00928 331 376 2.2E-25 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 SUPERFAMILY SSF140490 327 420 2.75E-35 T 06-07-2017 CAK95_RS22855 f71cc4b2e1b6e86e07ffda34440eeaa3 434 Pfam PF10531 SLBB domain 243 292 7.7E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS27465 f5f3c0065c10fa89c07c6bfa2c4f5a5b 393 Gene3D G3DSA:3.40.50.2000 207 339 1.4E-9 T 06-07-2017 CAK95_RS27465 f5f3c0065c10fa89c07c6bfa2c4f5a5b 393 Pfam PF00534 Glycosyl transferases group 1 207 342 6.5E-13 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS27465 f5f3c0065c10fa89c07c6bfa2c4f5a5b 393 SUPERFAMILY SSF53756 4 374 2.93E-36 T 06-07-2017 CAK95_RS15950 0c7ec668ffaff4537bd48352a73887e1 295 Gene3D G3DSA:3.60.21.10 3 266 3.5E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS15950 0c7ec668ffaff4537bd48352a73887e1 295 SUPERFAMILY SSF56300 4 271 3.8E-34 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS15950 0c7ec668ffaff4537bd48352a73887e1 295 Pfam PF00149 Calcineurin-like phosphoesterase 5 224 9.1E-10 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS15445 4ad98326ba12129ef2451928f91b67c1 487 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 309 346 3.0E-8 T 06-07-2017 IPR011964 YVTN beta-propeller repeat CAK95_RS15445 4ad98326ba12129ef2451928f91b67c1 487 Pfam PF10282 Lactonase, 7-bladed beta-propeller 125 288 9.1E-6 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAK95_RS15445 4ad98326ba12129ef2451928f91b67c1 487 Gene3D G3DSA:2.130.10.10 38 351 8.0E-55 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS15445 4ad98326ba12129ef2451928f91b67c1 487 SUPERFAMILY SSF50974 18 350 8.37E-64 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CAK95_RS20825 3398e0df7e17580bed859856f8a827a7 153 Pfam PF01592 NifU-like N terminal domain 9 123 6.2E-9 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAK95_RS20825 3398e0df7e17580bed859856f8a827a7 153 SUPERFAMILY SSF82649 1 142 2.62E-41 T 06-07-2017 CAK95_RS20825 3398e0df7e17580bed859856f8a827a7 153 Gene3D G3DSA:3.90.1010.10 5 146 2.3E-20 T 06-07-2017 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Gene3D G3DSA:3.40.190.10 90 172 5.3E-32 T 06-07-2017 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Gene3D G3DSA:3.40.190.10 276 303 5.3E-32 T 06-07-2017 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Gene3D G3DSA:1.10.10.10 1 84 2.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 SUPERFAMILY SSF53850 90 299 3.8E-43 T 06-07-2017 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 SUPERFAMILY SSF46785 2 84 1.58E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Pfam PF03466 LysR substrate binding domain 95 301 5.8E-24 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Gene3D G3DSA:3.40.190.10 173 269 7.6E-22 T 06-07-2017 CAK95_RS28240 57f7dd581a6799b5a3e294e015d1b968 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 4.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 Pfam PF13247 4Fe-4S dicluster domain 52 164 8.7E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 Gene3D G3DSA:3.30.70.20 63 118 3.2E-18 T 06-07-2017 CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 Gene3D G3DSA:3.30.70.20 119 176 1.1E-21 T 06-07-2017 CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 Gene3D G3DSA:3.30.70.20 3 62 1.1E-21 T 06-07-2017 CAK95_RS27825 edd85c717591cddf4ef6ac2b3927292c 198 SUPERFAMILY SSF54862 1 180 1.05E-45 T 06-07-2017 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 SUPERFAMILY SSF52096 19 201 3.32E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 06-07-2017 IPR033135 ClpP, histidine active site CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 12 201 4.5E-94 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 06-07-2017 IPR018215 ClpP, Ser active site CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 8.2E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 8.2E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 PRINTS PR00127 Clp protease catalytic subunit P signature 177 196 8.2E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 8.2E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 8.2E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 Pfam PF00574 Clp protease 22 201 3.2E-83 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 Gene3D G3DSA:3.90.226.10 12 201 8.3E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22705 ab21d15c799d4dcf8782768f934d4cd1 214 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 202 41.895 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK95_RS10700 2aa870b3aa1b12548fc5459879327cb0 278 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 255 2.3E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS18905 6b7fe0bbf2209718d9945d4b286523df 320 SUPERFAMILY SSF52467 49 187 2.29E-9 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS18905 6b7fe0bbf2209718d9945d4b286523df 320 Gene3D G3DSA:3.40.50.1220 38 129 2.7E-6 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS18905 6b7fe0bbf2209718d9945d4b286523df 320 Pfam PF13289 SIR2-like domain 76 218 2.0E-14 T 06-07-2017 CAK95_RS21575 fb70df2385ed157d776eef0009b6e862 133 SUPERFAMILY SSF88723 1 124 4.21E-18 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS21575 fb70df2385ed157d776eef0009b6e862 133 Gene3D G3DSA:3.40.50.1010 1 129 7.2E-33 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS21575 fb70df2385ed157d776eef0009b6e862 133 Pfam PF01850 PIN domain 4 121 1.2E-9 T 06-07-2017 IPR002716 PIN domain CAK95_RS21575 fb70df2385ed157d776eef0009b6e862 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 130 10.109 T 06-07-2017 IPR022907 VapC family GO:0004540 CAK95_RS21700 893e8ab7bed6aba5f8411aa1b8f31011 154 Gene3D G3DSA:3.10.490.10 2 141 8.8E-39 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK95_RS21700 893e8ab7bed6aba5f8411aa1b8f31011 154 Pfam PF13772 AIG2-like family 54 134 7.3E-16 T 06-07-2017 CAK95_RS21700 893e8ab7bed6aba5f8411aa1b8f31011 154 SUPERFAMILY SSF110857 5 104 9.03E-19 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK95_RS16275 3cdb67942521a2928f31ab40a48b8a20 155 SUPERFAMILY SSF69118 24 152 3.53E-30 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS16275 3cdb67942521a2928f31ab40a48b8a20 155 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 141 1.5E-14 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS16275 3cdb67942521a2928f31ab40a48b8a20 155 Gene3D G3DSA:1.20.1290.10 29 151 7.3E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 SUPERFAMILY SSF56003 321 725 1.57E-96 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Gene3D G3DSA:3.30.365.10 559 724 2.6E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 SMART SM01008 216 295 1.7E-19 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 46 191 1.5E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 318 563 1.9E-26 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 597 678 3.0E-9 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 PIRSF PIRSF036389 1 730 5.3E-217 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Gene3D G3DSA:3.30.365.10 46 193 2.2E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 SUPERFAMILY SSF56003 20 249 4.19E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Gene3D G3DSA:3.90.1170.50 194 293 5.3E-21 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS15015 ff86983766104262ea4f342a81104d80 731 Gene3D G3DSA:3.30.365.10 393 558 8.0E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18935 94114488fac8af6a54a3dfea3cdc1bf5 79 Pfam PF13711 Domain of unknown function (DUF4160) 12 60 8.6E-8 T 06-07-2017 IPR025427 Protein of unknown function DUF4160 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 9.4E-57 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 28.235 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 SUPERFAMILY SSF50193 1 122 3.66E-52 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 SMART SM01374 1 122 1.0E-84 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 Gene3D G3DSA:2.40.150.20 1 122 4.8E-55 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK95_RS21315 3b1b074d527ff82caeb039ad978a38a1 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 9.4E-56 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK95_RS08070 0bfefb05b96ad87362394702a209798d 279 Pfam PF03618 Kinase/pyrophosphorylase 11 267 9.4E-90 T 06-07-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CAK95_RS08070 0bfefb05b96ad87362394702a209798d 279 Gene3D G3DSA:3.40.50.300 186 273 3.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08070 0bfefb05b96ad87362394702a209798d 279 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 9 273 56.995 T 06-07-2017 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CAK95_RS09640 c335a684e908177a3cc36dd8e18c0f98 388 SUPERFAMILY SSF51726 9 372 1.31E-53 T 06-07-2017 CAK95_RS09640 c335a684e908177a3cc36dd8e18c0f98 388 Gene3D G3DSA:3.20.20.210 7 382 7.8E-73 T 06-07-2017 CAK95_RS09640 c335a684e908177a3cc36dd8e18c0f98 388 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 164 362 2.6E-9 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS09640 c335a684e908177a3cc36dd8e18c0f98 388 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 9 85 4.3E-6 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 Gene3D G3DSA:3.40.50.1860 8 118 9.3E-19 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 SUPERFAMILY SSF53681 113 215 1.18E-14 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 SUPERFAMILY SSF53681 8 118 8.28E-18 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 Gene3D G3DSA:3.40.50.1860 119 220 5.9E-15 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 198 208 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS19315 207fccd5ac1436432c3c569a4cb3778d 239 Pfam PF01177 Asp/Glu/Hydantoin racemase 13 228 2.9E-32 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 7 312 1.5E-43 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 SUPERFAMILY SSF53850 29 311 1.18E-47 T 06-07-2017 CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 Gene3D G3DSA:3.40.190.10 242 312 3.7E-24 T 06-07-2017 CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 Gene3D G3DSA:3.40.190.10 29 107 3.7E-24 T 06-07-2017 CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 Gene3D G3DSA:3.40.190.10 116 217 7.3E-15 T 06-07-2017 CAK95_RS18435 acee4950c5e7373c186ab26581c42585 320 Pfam PF16868 NMT1-like family 35 311 1.2E-26 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS11290 793900c0a0b0ab174de470c686ccdc82 166 PIRSF PIRSF032064 1 164 1.3E-45 T 06-07-2017 IPR010593 Protein of unknown function DUF1159 CAK95_RS11290 793900c0a0b0ab174de470c686ccdc82 166 Pfam PF05258 Protein of unknown function (DUF721) 11 112 2.5E-18 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 8.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 SUPERFAMILY SSF51735 5 243 1.99E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 1.2E-52 T 06-07-2017 CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 Gene3D G3DSA:3.40.50.720 4 243 7.8E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23545 320e08fee016fe0f0a04ad5ce41c7cea 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 SUPERFAMILY SSF47789 257 332 1.83E-26 T 06-07-2017 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 SMART SM00662 31 238 7.5E-92 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Gene3D G3DSA:2.170.120.12 75 181 9.6E-43 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 37 232 2.3E-23 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 SUPERFAMILY SSF56553 61 182 1.57E-39 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 259 314 1.1E-24 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Gene3D G3DSA:1.10.150.20 254 334 4.3E-36 T 06-07-2017 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 11 323 35.313 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 70 162 1.7E-20 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 Gene3D G3DSA:3.30.1360.10 30 74 4.4E-8 T 06-07-2017 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 33 323 5.0E-115 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 SUPERFAMILY SSF55257 183 235 1.03E-29 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 SUPERFAMILY SSF55257 11 61 1.03E-29 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21385 a3ac25a67c09e18d4969b106b9133d50 343 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 263 332 4.0E-34 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 Gene3D G3DSA:2.160.10.10 5 188 1.8E-40 T 06-07-2017 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 SUPERFAMILY SSF51161 5 253 1.51E-64 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 6 259 3.7E-95 T 06-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 PIRSF PIRSF000456 3 267 1.1E-95 T 06-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 Gene3D G3DSA:1.20.1180.10 195 253 3.6E-16 T 06-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 178 253 3.5E-19 T 06-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 141 1.3E-7 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23010 e8181f4ec8397b8af9ba1bd4198be514 277 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 42 2.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 Gene3D G3DSA:3.40.50.1470 1 184 1.1E-66 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 Pfam PF01195 Peptidyl-tRNA hydrolase 3 173 1.4E-51 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 SUPERFAMILY SSF53178 1 184 8.5E-66 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 168 1.0E-55 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 177 33.477 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAK95_RS13490 c81b7051c98f4c306ed962c9ae5bc701 202 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAK95_RS01035 276b06c1e9f7b65c714f9ca1964fcca3 234 SMART SM00382 30 213 1.6E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS01035 276b06c1e9f7b65c714f9ca1964fcca3 234 Gene3D G3DSA:3.40.50.300 3 227 4.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01035 276b06c1e9f7b65c714f9ca1964fcca3 234 SUPERFAMILY SSF52540 3 226 1.57E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01035 276b06c1e9f7b65c714f9ca1964fcca3 234 Pfam PF00005 ABC transporter 23 162 1.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11730 ef56aaa432b08e2e78ddc23586a37782 516 Gene3D G3DSA:3.30.70.1230 66 206 4.2E-9 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS11730 ef56aaa432b08e2e78ddc23586a37782 516 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 277 406 3.0E-4 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS11730 ef56aaa432b08e2e78ddc23586a37782 516 SUPERFAMILY SSF55073 275 452 4.24E-13 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS11730 ef56aaa432b08e2e78ddc23586a37782 516 SUPERFAMILY SSF55073 60 206 2.67E-16 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS11730 ef56aaa432b08e2e78ddc23586a37782 516 Gene3D G3DSA:3.30.70.1230 276 406 1.5E-8 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS25515 ef4edea4e4c5ed1f0a93797fc9a209ec 471 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 433 1.7E-114 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS25515 ef4edea4e4c5ed1f0a93797fc9a209ec 471 PIRSF PIRSF006066 6 445 7.1E-70 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS25515 ef4edea4e4c5ed1f0a93797fc9a209ec 471 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 438 1.5E-97 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Gene3D G3DSA:2.40.50.100 2 97 1.6E-34 T 06-07-2017 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Pfam PF00364 Biotin-requiring enzyme 4 77 1.5E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 SUPERFAMILY SSF52777 219 450 6.67E-80 T 06-07-2017 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Pfam PF02817 e3 binding domain 145 179 5.9E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 5 451 2.6E-174 T 06-07-2017 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Gene3D G3DSA:3.30.559.10 218 450 2.1E-87 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 450 1.3E-80 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 SUPERFAMILY SSF47005 139 182 2.22E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 SUPERFAMILY SSF51230 1 97 7.07E-29 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS23175 dd0c64323d5e56083c1ca28fecf8f32e 451 Gene3D G3DSA:4.10.320.10 137 184 5.1E-18 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS17015 133586b95efb0ab3a583cd9cc2c6dde4 141 SUPERFAMILY SSF46458 2 132 4.66E-36 T 06-07-2017 IPR009050 Globin-like CAK95_RS17015 133586b95efb0ab3a583cd9cc2c6dde4 141 Pfam PF00042 Globin 5 98 3.4E-11 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 CAK95_RS17015 133586b95efb0ab3a583cd9cc2c6dde4 141 PRINTS PR00188 Plant globin signature 27 47 4.0E-5 T 06-07-2017 IPR001032 Leghaemoglobin GO:0019825|GO:0020037 CAK95_RS17015 133586b95efb0ab3a583cd9cc2c6dde4 141 PRINTS PR00188 Plant globin signature 105 131 4.0E-5 T 06-07-2017 IPR001032 Leghaemoglobin GO:0019825|GO:0020037 CAK95_RS17015 133586b95efb0ab3a583cd9cc2c6dde4 141 Gene3D G3DSA:1.10.490.10 2 137 3.0E-42 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK95_RS12145 dece9a80c34cd327b9c2d3c7baa13017 322 Gene3D G3DSA:3.40.50.720 7 180 1.0E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12145 dece9a80c34cd327b9c2d3c7baa13017 322 SUPERFAMILY SSF48179 179 289 6.23E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS12145 dece9a80c34cd327b9c2d3c7baa13017 322 SUPERFAMILY SSF51735 9 176 7.19E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12145 dece9a80c34cd327b9c2d3c7baa13017 322 Pfam PF02153 Prephenate dehydrogenase 22 280 2.5E-81 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 231 2.7E-66 T 06-07-2017 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 SUPERFAMILY SSF53681 1 116 2.4E-36 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 SUPERFAMILY SSF53681 122 229 7.63E-28 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 Gene3D G3DSA:3.40.50.1860 1 112 5.9E-42 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 Gene3D G3DSA:3.40.50.1860 113 216 6.0E-28 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS05185 fbe399d595fefbc16f0a8d558f87acf4 238 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 8.4E-52 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SMART SM00487 196 612 1.6E-23 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Pfam PF04851 Type III restriction enzyme, res subunit 198 326 7.1E-12 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Pfam PF12344 Ultra-violet resistance protein B 738 779 2.8E-21 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Hamap MF_00204 UvrABC system protein B [uvrB]. 190 848 40.908 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:3.30.2060.10 347 424 1.4E-11 T 06-07-2017 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:4.10.860.10 809 851 2.3E-16 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Pfam PF00271 Helicase conserved C-terminal domain 629 731 5.8E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 193 846 4.8E-300 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SUPERFAMILY SSF52540 645 761 1.14E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SUPERFAMILY SSF52540 222 269 1.14E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SMART SM00490 646 732 9.2E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Pfam PF02151 UvrB/uvrC motif 814 847 3.1E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:3.40.50.300 612 767 6.5E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:3.40.50.300 194 276 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:3.40.50.300 574 595 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 Gene3D G3DSA:3.40.50.300 464 524 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SUPERFAMILY SSF52540 193 599 9.51E-128 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16300 de906ed0c92f3fa8e79f8f020260692a 974 SUPERFAMILY SSF46600 808 847 2.22E-10 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK95_RS13450 9beac2064481ab9d45abde3f1c541ebd 366 Gene3D G3DSA:3.40.50.720 1 140 6.8E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13450 9beac2064481ab9d45abde3f1c541ebd 366 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 124 1.0E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS13450 9beac2064481ab9d45abde3f1c541ebd 366 SUPERFAMILY SSF55347 132 278 1.44E-15 T 06-07-2017 CAK95_RS13450 9beac2064481ab9d45abde3f1c541ebd 366 Gene3D G3DSA:3.30.360.10 141 341 9.6E-24 T 06-07-2017 CAK95_RS13450 9beac2064481ab9d45abde3f1c541ebd 366 SUPERFAMILY SSF51735 5 152 1.51E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00625 421b9fba00c6c2b17770f617a2c9876e 958 Pfam PF07584 Aerotolerance regulator N-terminal 8 81 9.2E-17 T 06-07-2017 IPR024163 Aerotolerance regulator, N-terminal CAK95_RS00625 421b9fba00c6c2b17770f617a2c9876e 958 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 8 86 1.6E-19 T 06-07-2017 IPR011933 Double transmembrane domain CAK95_RS00625 421b9fba00c6c2b17770f617a2c9876e 958 SUPERFAMILY SSF52317 369 522 2.75E-7 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS00625 421b9fba00c6c2b17770f617a2c9876e 958 Pfam PF13709 Domain of unknown function (DUF4159) 714 938 1.2E-52 T 06-07-2017 IPR025297 Domain of unknown function DUF4159 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Gene3D G3DSA:1.10.1160.10 236 317 7.7E-32 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 1.1E-26 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 1.1E-26 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 182 192 1.1E-26 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 206 1.1E-26 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 1.1E-26 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 SUPERFAMILY SSF48163 302 470 2.49E-36 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 307 3.2E-94 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Gene3D G3DSA:3.90.800.10 70 183 2.2E-34 T 06-07-2017 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Gene3D G3DSA:1.10.10.350 377 471 1.3E-27 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Gene3D G3DSA:3.40.50.620 184 233 1.5E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Gene3D G3DSA:3.40.50.620 5 69 1.5E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 470 1.8E-151 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 472 32.503 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK95_RS23050 2880c9e20d29da9476bb2e0259c57ca2 480 SUPERFAMILY SSF52374 4 301 4.83E-107 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 34 408 2.9E-150 T 06-07-2017 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 Pfam PF03486 HI0933-like protein 12 402 8.3E-108 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 Gene3D G3DSA:3.50.50.60 350 404 2.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 Gene3D G3DSA:3.50.50.60 12 197 2.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 Gene3D G3DSA:2.40.30.10 212 285 1.1E-4 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 SUPERFAMILY SSF51905 348 406 5.11E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 SUPERFAMILY SSF51905 12 199 5.11E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 SUPERFAMILY SSF160996 212 348 1.12E-10 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 PRINTS PR00419 Adrenodoxin reductase family signature 12 34 1.1E-9 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 PRINTS PR00419 Adrenodoxin reductase family signature 35 48 1.1E-9 T 06-07-2017 CAK95_RS05770 35b551fdaa8b917fd7e97a4e41e99033 416 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 13 401 1.2E-87 T 06-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Gene3D G3DSA:3.30.365.10 51 184 9.6E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 SUPERFAMILY SSF56003 327 738 8.61E-107 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Gene3D G3DSA:3.30.365.10 330 447 1.2E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Gene3D G3DSA:3.30.365.10 535 738 1.4E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 PIRSF PIRSF036389 3 736 2.6E-232 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 SMART SM01008 221 299 2.1E-10 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 601 681 1.2E-10 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 328 562 1.5E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 49 181 2.1E-9 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 SUPERFAMILY SSF56003 49 249 2.02E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS11555 de5f0e0c5e94ca06638c9a832b7e6f96 739 Gene3D G3DSA:3.90.1170.50 192 268 5.1E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 PRINTS PR01713 Nucleotide sugar epimerase signature 32 48 1.6E-27 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 PRINTS PR01713 Nucleotide sugar epimerase signature 219 234 1.6E-27 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 PRINTS PR01713 Nucleotide sugar epimerase signature 298 315 1.6E-27 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 PRINTS PR01713 Nucleotide sugar epimerase signature 259 274 1.6E-27 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 SUPERFAMILY SSF51735 6 335 8.06E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 Gene3D G3DSA:3.90.25.10 202 221 2.3E-20 T 06-07-2017 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 Gene3D G3DSA:3.90.25.10 263 334 2.3E-20 T 06-07-2017 CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 Gene3D G3DSA:3.40.50.720 6 201 2.7E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17760 cd7358ce0db3fd41e6532948f681e39c 338 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 265 1.4E-58 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS16475 b6d6b91787f91b92b022f88d0aaee70d 315 SUPERFAMILY SSF53474 20 169 1.67E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16475 b6d6b91787f91b92b022f88d0aaee70d 315 SUPERFAMILY SSF53474 204 308 1.67E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16475 b6d6b91787f91b92b022f88d0aaee70d 315 Pfam PF12146 Serine aminopeptidase, S33 39 294 3.7E-38 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK95_RS16475 b6d6b91787f91b92b022f88d0aaee70d 315 Gene3D G3DSA:3.40.50.1820 235 308 3.2E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16475 b6d6b91787f91b92b022f88d0aaee70d 315 Gene3D G3DSA:3.40.50.1820 20 170 3.2E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22050 f951baf782c95e2e8df33d27cc18f2b1 244 Gene3D G3DSA:3.90.79.10 11 218 5.3E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS22050 f951baf782c95e2e8df33d27cc18f2b1 244 Pfam PF00293 NUDIX domain 26 201 3.7E-6 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS22050 f951baf782c95e2e8df33d27cc18f2b1 244 SUPERFAMILY SSF55811 15 71 2.35E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS22050 f951baf782c95e2e8df33d27cc18f2b1 244 SUPERFAMILY SSF55811 141 215 2.35E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS22050 f951baf782c95e2e8df33d27cc18f2b1 244 SUPERFAMILY SSF55811 102 113 2.35E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 SUPERFAMILY SSF54373 174 272 7.45E-40 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 Gene3D G3DSA:3.40.50.720 3 69 2.1E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 Gene3D G3DSA:3.50.50.60 92 145 2.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 Gene3D G3DSA:3.30.9.10 146 296 6.5E-64 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 1.0E-26 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.0E-26 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.0E-26 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.0E-26 T 06-07-2017 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 Pfam PF01494 FAD binding domain 2 337 1.2E-72 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 SUPERFAMILY SSF51905 1 171 1.04E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS24885 9a9ec7cef1b576f9e1de10ac12d25648 388 SUPERFAMILY SSF51905 271 384 1.04E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21670 bb1c3d27ee8d909e9ee7a3916b34de77 132 SUPERFAMILY SSF54637 6 129 7.75E-34 T 06-07-2017 IPR029069 HotDog domain CAK95_RS21670 bb1c3d27ee8d909e9ee7a3916b34de77 132 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 123 3.1E-24 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS21670 bb1c3d27ee8d909e9ee7a3916b34de77 132 Gene3D G3DSA:3.10.129.10 4 127 6.4E-38 T 06-07-2017 IPR029069 HotDog domain CAK95_RS21670 bb1c3d27ee8d909e9ee7a3916b34de77 132 Pfam PF03061 Thioesterase superfamily 39 116 2.2E-16 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS26105 1e0d0dcb7579608cf464ff5aac9fb59f 157 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 118 1.4E-46 T 06-07-2017 IPR028973 PhnB-like CAK95_RS26105 1e0d0dcb7579608cf464ff5aac9fb59f 157 PIRSF PIRSF021700 1 157 5.4E-64 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CAK95_RS26105 1e0d0dcb7579608cf464ff5aac9fb59f 157 SUPERFAMILY SSF54593 3 155 1.48E-45 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS26105 1e0d0dcb7579608cf464ff5aac9fb59f 157 Gene3D G3DSA:3.10.180.10 3 128 7.5E-40 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 Pfam PF02567 Phenazine biosynthesis-like protein 8 294 2.4E-60 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 296 1.5E-69 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 SUPERFAMILY SSF54506 1 296 7.33E-60 T 06-07-2017 CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 PIRSF PIRSF016184 1 298 3.9E-83 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 Gene3D G3DSA:3.10.310.10 135 277 3.6E-35 T 06-07-2017 CAK95_RS14785 1ce023866430ac5dce1c15833bea1c5c 298 Gene3D G3DSA:3.10.310.10 2 115 1.9E-36 T 06-07-2017 CAK95_RS25445 80f0e4e9d578cbf08fec33471ad399c7 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 303 5.5E-30 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS15245 e592a22fa1ef652c16b42a615065fa6e 253 Pfam PF13531 Bacterial extracellular solute-binding protein 25 248 1.7E-32 T 06-07-2017 CAK95_RS15245 e592a22fa1ef652c16b42a615065fa6e 253 Gene3D G3DSA:3.40.190.10 23 158 5.0E-11 T 06-07-2017 CAK95_RS15245 e592a22fa1ef652c16b42a615065fa6e 253 SUPERFAMILY SSF53850 24 248 3.09E-34 T 06-07-2017 CAK95_RS02500 fc4a21d4fac00534031f01f89e6cf03c 84 Gene3D G3DSA:1.10.1220.10 22 72 1.4E-5 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK95_RS02500 fc4a21d4fac00534031f01f89e6cf03c 84 SUPERFAMILY SSF47598 34 74 2.45E-6 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK95_RS10660 58895767f3cb3ae9be3a3312b1d77bfa 126 Pfam PF07883 Cupin domain 41 103 2.1E-8 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS10660 58895767f3cb3ae9be3a3312b1d77bfa 126 Gene3D G3DSA:2.60.120.10 7 111 1.7E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS10660 58895767f3cb3ae9be3a3312b1d77bfa 126 SUPERFAMILY SSF51182 4 113 8.91E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 Gene3D G3DSA:1.10.287.180 1 75 3.1E-33 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 SUPERFAMILY SSF54534 81 156 2.75E-22 T 06-07-2017 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 Gene3D G3DSA:3.10.50.30 76 156 5.6E-30 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 1.8E-31 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 4.7E-28 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 SUPERFAMILY SSF46557 3 78 1.83E-27 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 7.2E-59 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 PIRSF PIRSF006092 1 157 1.2E-53 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAK95_RS13790 68295469462f5bb2fdec3a0fb8f4ec51 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 31.443 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CAK95_RS09950 15da7f225817768031b78e148e156646 420 Gene3D G3DSA:1.20.1250.20 46 215 2.3E-19 T 06-07-2017 CAK95_RS09950 15da7f225817768031b78e148e156646 420 SUPERFAMILY SSF103473 43 414 1.31E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS09950 15da7f225817768031b78e148e156646 420 Gene3D G3DSA:1.20.1250.20 240 414 5.5E-9 T 06-07-2017 CAK95_RS09950 15da7f225817768031b78e148e156646 420 Pfam PF07690 Major Facilitator Superfamily 50 355 4.3E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS03605 4f5fc9abde6895f9fe092bf6c4c8bc4c 34 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 12 29 5.1E-6 T 06-07-2017 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CAK95_RS03605 4f5fc9abde6895f9fe092bf6c4c8bc4c 34 Pfam PF08042 PqqA family 12 29 1.1E-6 T 06-07-2017 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CAK95_RS09685 8c1f0d0121fb987dff4ceff8558b9016 354 Pfam PF01758 Sodium Bile acid symporter family 47 241 2.0E-33 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CAK95_RS09685 8c1f0d0121fb987dff4ceff8558b9016 354 PIRSF PIRSF005508 1 344 3.1E-111 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAK95_RS09685 8c1f0d0121fb987dff4ceff8558b9016 354 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 328 2.5E-111 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 SUPERFAMILY SSF51556 60 319 2.15E-19 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 Gene3D G3DSA:2.30.40.10 307 364 2.6E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 Gene3D G3DSA:3.20.20.140 268 306 2.6E-4 T 06-07-2017 CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 SUPERFAMILY SSF51338 13 77 2.99E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 Gene3D G3DSA:2.30.40.10 1 97 8.5E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27695 5e831f46b2ff1a98c6c18c625778972d 398 Pfam PF01979 Amidohydrolase family 58 364 1.2E-12 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 Gene3D G3DSA:1.10.10.10 2 85 7.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 Pfam PF03466 LysR substrate binding domain 87 291 5.0E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 SUPERFAMILY SSF53850 88 294 9.41E-33 T 06-07-2017 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 SUPERFAMILY SSF46785 3 103 1.58E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 Gene3D G3DSA:3.40.190.10 88 181 1.7E-11 T 06-07-2017 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 Gene3D G3DSA:3.40.190.10 182 262 1.3E-13 T 06-07-2017 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 62 7.2E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12285 f25b72de02496c358c8518534f90c445 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 SUPERFAMILY SSF54211 87 166 8.34E-26 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 Pfam PF03719 Ribosomal protein S5, C-terminal domain 95 165 5.5E-30 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 Pfam PF00333 Ribosomal protein S5, N-terminal domain 19 82 3.8E-29 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 16 170 1.2E-66 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 Gene3D G3DSA:3.30.230.10 83 165 2.7E-33 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 SUPERFAMILY SSF54768 16 83 3.03E-23 T 06-07-2017 CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 Gene3D G3DSA:3.30.160.20 16 79 1.4E-30 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS21350 9b1c2c4c84b5f38705145c3427afcadf 186 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 171 35.839 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS23375 9701bd92ada4c6afec6bcd59ddc3bd35 489 Pfam PF03354 Phage Terminase 31 471 6.3E-19 T 06-07-2017 IPR005021 Phage terminase CAK95_RS26735 8faf8c5a0f4df3982331364aab3de862 118 SUPERFAMILY SSF54292 17 100 2.88E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS26735 8faf8c5a0f4df3982331364aab3de862 118 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 103 1.4E-17 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26735 8faf8c5a0f4df3982331364aab3de862 118 Gene3D G3DSA:3.10.20.30 4 100 3.8E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS06435 9295e1929b6326e4b11979b91ca65a92 214 Gene3D G3DSA:3.40.50.1820 10 206 3.0E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06435 9295e1929b6326e4b11979b91ca65a92 214 SUPERFAMILY SSF53474 7 152 2.46E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09510 b97b37d64a20d7cd1088bf80afce70ef 342 Gene3D G3DSA:3.20.20.30 4 329 3.2E-84 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS09510 b97b37d64a20d7cd1088bf80afce70ef 342 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 330 3.5E-126 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAK95_RS09510 b97b37d64a20d7cd1088bf80afce70ef 342 SUPERFAMILY SSF51679 4 329 1.3E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS09510 b97b37d64a20d7cd1088bf80afce70ef 342 Pfam PF00296 Luciferase-like monooxygenase 14 302 3.3E-34 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 SUPERFAMILY SSF54292 3 79 1.17E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 Gene3D G3DSA:3.10.20.30 3 75 3.8E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 Gene3D G3DSA:1.10.150.120 76 155 1.6E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 55 1.3E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 Pfam PF01799 [2Fe-2S] binding domain 74 147 7.6E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS20375 72445f0e97c1fa53d19758f3921bcc8a 156 SUPERFAMILY SSF47741 85 154 2.09E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 SMART SM00939 285 543 8.5E-61 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 Gene3D G3DSA:2.60.120.260 319 547 1.1E-48 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 208 547 1.1E-45 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 20 168 2.0E-38 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 SUPERFAMILY SSF49785 314 547 2.34E-37 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 Gene3D G3DSA:3.40.50.1820 18 163 2.1E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 Gene3D G3DSA:3.40.50.1820 210 318 2.1E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 301 542 9.9E-45 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 SUPERFAMILY SSF53474 18 321 3.39E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00330 a7db3669a9f7c4b68c4f3a8014d091ee 551 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 262 1.6E-44 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK95_RS17590 cbe6e6bd79db70244043ca588d7d502c 196 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 191 36.533 T 06-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 CAK95_RS17590 cbe6e6bd79db70244043ca588d7d502c 196 Pfam PF13580 SIS domain 10 148 7.6E-29 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS17590 cbe6e6bd79db70244043ca588d7d502c 196 SUPERFAMILY SSF53697 4 192 1.84E-50 T 06-07-2017 CAK95_RS17590 cbe6e6bd79db70244043ca588d7d502c 196 Gene3D G3DSA:3.40.50.10490 4 193 1.2E-60 T 06-07-2017 CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 Gene3D G3DSA:1.10.10.10 11 76 2.0E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 SMART SM00345 19 77 8.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 75 5.5E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 Gene3D G3DSA:1.20.120.530 81 232 7.9E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 SUPERFAMILY SSF46785 12 81 1.61E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 SMART SM00895 87 221 9.7E-14 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 Pfam PF07729 FCD domain 87 220 2.5E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS24875 edd7a6c3471eb8dbecf46ba70a0eca4b 244 SUPERFAMILY SSF48008 84 229 4.71E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28165 1a2acf0d082e4c338ebb233249a9c2cf 80 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 3.5E-6 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 SMART SM00345 25 83 2.9E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 Pfam PF07729 FCD domain 93 223 1.1E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 SMART SM00895 93 224 3.2E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 Gene3D G3DSA:1.20.120.530 88 235 3.1E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 Gene3D G3DSA:1.10.10.10 10 84 2.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 SUPERFAMILY SSF48008 89 231 1.12E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 SUPERFAMILY SSF46785 17 87 4.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04410 cc7e54fee258293ecde16265bac96157 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 1.7E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04120 165098b473c2b30bc8a3f4626766f2ce 173 SUPERFAMILY SSF55729 9 153 2.17E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04120 165098b473c2b30bc8a3f4626766f2ce 173 Pfam PF13302 Acetyltransferase (GNAT) domain 15 150 1.4E-21 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS04120 165098b473c2b30bc8a3f4626766f2ce 173 Gene3D G3DSA:3.40.630.30 8 155 4.6E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS16495 dc167690f50cd4b6472791ce78d0d1a1 448 Gene3D G3DSA:1.20.1250.20 51 239 1.4E-32 T 06-07-2017 CAK95_RS16495 dc167690f50cd4b6472791ce78d0d1a1 448 Gene3D G3DSA:1.20.1250.20 248 440 7.5E-14 T 06-07-2017 CAK95_RS16495 dc167690f50cd4b6472791ce78d0d1a1 448 Pfam PF07690 Major Facilitator Superfamily 55 289 6.3E-33 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS16495 dc167690f50cd4b6472791ce78d0d1a1 448 SUPERFAMILY SSF103473 44 445 5.23E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS13120 91e81362669bdc12af3907c97e401aef 441 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 436 3.9E-95 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS13120 91e81362669bdc12af3907c97e401aef 441 PIRSF PIRSF006066 6 441 1.2E-68 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS13120 91e81362669bdc12af3907c97e401aef 441 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 430 8.3E-87 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS14810 3e82b2037b41b38350a2adc9b13f030b 669 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 19 631 5.1E-111 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein CAK95_RS14810 3e82b2037b41b38350a2adc9b13f030b 669 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 117 551 2.6E-58 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 Gene3D G3DSA:1.10.1660.10 59 130 1.0E-25 T 06-07-2017 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 SMART SM00422 4 73 1.5E-22 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 Pfam PF09278 MerR, DNA binding 47 110 1.1E-20 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.9E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.9E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.9E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 SUPERFAMILY SSF46955 6 129 1.25E-32 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 Pfam PF00376 MerR family regulatory protein 6 42 1.2E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS19740 d8dfca0c077ab722fdd4d5ffa75b1dc0 134 Gene3D G3DSA:1.10.1660.10 5 58 1.4E-23 T 06-07-2017 CAK95_RS09545 cb1994e930976c0b5e449a6098167293 309 Gene3D G3DSA:3.30.70.1070 225 306 8.2E-4 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS09545 cb1994e930976c0b5e449a6098167293 309 Gene3D G3DSA:1.10.530.10 47 168 3.5E-32 T 06-07-2017 CAK95_RS09545 cb1994e930976c0b5e449a6098167293 309 Pfam PF01464 Transglycosylase SLT domain 47 153 8.0E-18 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS09545 cb1994e930976c0b5e449a6098167293 309 Pfam PF05036 Sporulation related domain 225 306 7.7E-9 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS09545 cb1994e930976c0b5e449a6098167293 309 SUPERFAMILY SSF53955 44 166 2.48E-33 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS22980 ff92be9c764647c23f10acb1c824767d 288 Pfam PF01148 Cytidylyltransferase family 26 271 8.4E-52 T 06-07-2017 CAK95_RS22980 ff92be9c764647c23f10acb1c824767d 288 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 233 259 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PIRSF PIRSF000166 2 312 6.2E-109 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 201 225 - T 06-07-2017 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 22 312 51.512 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 Pfam PF01218 Coproporphyrinogen III oxidase 30 311 4.2E-85 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 SUPERFAMILY SSF102886 21 312 1.96E-109 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PRINTS PR00073 Coprogen oxidase signature 297 312 2.1E-43 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PRINTS PR00073 Coprogen oxidase signature 125 149 2.1E-43 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PRINTS PR00073 Coprogen oxidase signature 197 226 2.1E-43 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PRINTS PR00073 Coprogen oxidase signature 269 296 2.1E-43 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 PRINTS PR00073 Coprogen oxidase signature 62 78 2.1E-43 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS00575 6fc42d394dd958711f588d4a56812277 312 Gene3D G3DSA:3.40.1500.10 21 311 4.5E-108 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS25290 2a2dc598475e23c2a1382226f0868545 169 SMART SM00448 35 146 3.7E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS25290 2a2dc598475e23c2a1382226f0868545 169 Gene3D G3DSA:3.40.50.2300 34 153 1.7E-27 T 06-07-2017 CAK95_RS25290 2a2dc598475e23c2a1382226f0868545 169 Pfam PF00072 Response regulator receiver domain 37 146 1.4E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS25290 2a2dc598475e23c2a1382226f0868545 169 SUPERFAMILY SSF52172 35 160 2.99E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS11750 134dbd33aa23797a66ace191c08fda93 321 SUPERFAMILY SSF53850 106 285 1.0E-7 T 06-07-2017 CAK95_RS11750 134dbd33aa23797a66ace191c08fda93 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 318 2.0E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS11750 134dbd33aa23797a66ace191c08fda93 321 PIRSF PIRSF017082 1 320 2.7E-60 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 SUPERFAMILY SSF52540 2 216 6.95E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 Gene3D G3DSA:3.40.50.300 2 215 9.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 Pfam PF00005 ABC transporter 18 165 1.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 SMART SM00382 27 216 3.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12115 06610c6e18b7dc6e9def22776ac7e9af 219 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 5.9E-83 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 Pfam PF08245 Mur ligase middle domain 46 266 1.4E-9 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 PIRSF PIRSF001563 1 436 1.9E-101 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 68 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 SUPERFAMILY SSF53244 291 434 1.05E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 Gene3D G3DSA:3.90.190.20 291 432 1.2E-24 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 Gene3D G3DSA:3.40.1190.10 2 289 1.1E-91 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 SUPERFAMILY SSF53623 3 288 2.59E-86 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 430 6.4E-104 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAK95_RS10995 07fc83001371022820e3c54727d69448 438 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 140 155 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAK95_RS13175 5e7f2d64c1914930ee8d96370811c750 334 Pfam PF01384 Phosphate transporter family 173 323 9.4E-53 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAK95_RS13175 5e7f2d64c1914930ee8d96370811c750 334 Pfam PF01384 Phosphate transporter family 24 164 3.8E-37 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAK95_RS23400 2f33276108b61831a03348a3b94f6127 392 SUPERFAMILY SSF56349 94 377 1.27E-51 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS23400 2f33276108b61831a03348a3b94f6127 392 Gene3D G3DSA:1.10.443.10 214 375 4.8E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS23400 2f33276108b61831a03348a3b94f6127 392 Pfam PF13356 Domain of unknown function (DUF4102) 14 89 2.9E-11 T 06-07-2017 IPR025166 Domain of unknown function DUF4102 CAK95_RS23400 2f33276108b61831a03348a3b94f6127 392 Gene3D G3DSA:1.10.150.130 95 187 4.4E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS23400 2f33276108b61831a03348a3b94f6127 392 Pfam PF00589 Phage integrase family 223 366 8.0E-14 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 Gene3D G3DSA:1.10.10.10 22 158 3.9E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 SMART SM00347 45 145 2.0E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 SUPERFAMILY SSF46785 25 160 4.85E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 5.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 5.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 5.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS01655 84a28c4c87821fe8c5dfcfe1a38a043c 179 Pfam PF12802 MarR family 51 109 4.6E-14 T 06-07-2017 CAK95_RS26205 ab062b6017977ab118af0259b8e1d3ef 330 Gene3D G3DSA:2.60.120.330 29 327 1.2E-80 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK95_RS26205 ab062b6017977ab118af0259b8e1d3ef 330 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 30 126 4.7E-22 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAK95_RS26205 ab062b6017977ab118af0259b8e1d3ef 330 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 190 297 1.2E-17 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS26205 ab062b6017977ab118af0259b8e1d3ef 330 SUPERFAMILY SSF51197 28 328 1.32E-79 T 06-07-2017 CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 SUPERFAMILY SSF52518 333 504 5.0E-29 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 177 268 3.8E-11 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 158 5.7E-26 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Gene3D G3DSA:3.40.50.970 11 162 1.0E-29 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 SUPERFAMILY SSF52518 5 159 1.13E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Gene3D G3DSA:3.40.50.1220 173 344 1.7E-14 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 390 409 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Gene3D G3DSA:3.40.50.970 345 505 2.2E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 362 499 7.5E-16 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS17685 d68b5b9dd80546507399b7e1f8a695bf 514 SUPERFAMILY SSF52467 169 263 3.27E-13 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS08615 0fd2d9275b2eb7aaa35f74688023a444 410 SUPERFAMILY SSF53335 298 361 1.93E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08615 0fd2d9275b2eb7aaa35f74688023a444 410 SUPERFAMILY SSF53335 28 99 1.93E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08615 0fd2d9275b2eb7aaa35f74688023a444 410 Pfam PF11899 Protein of unknown function (DUF3419) 30 405 3.0E-111 T 06-07-2017 IPR021829 Protein of unknown function DUF3419 CAK95_RS08615 0fd2d9275b2eb7aaa35f74688023a444 410 Gene3D G3DSA:3.40.50.150 300 382 8.4E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08615 0fd2d9275b2eb7aaa35f74688023a444 410 Gene3D G3DSA:3.40.50.150 48 96 8.4E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 SUPERFAMILY SSF50494 11 196 7.02E-25 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 SMART SM00228 201 275 3.7E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 Gene3D G3DSA:2.40.10.10 29 103 1.9E-12 T 06-07-2017 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 Gene3D G3DSA:2.40.10.10 104 202 3.3E-10 T 06-07-2017 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 PRINTS PR00834 HtrA/DegQ protease family signature 62 82 2.3E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 PRINTS PR00834 HtrA/DegQ protease family signature 233 245 2.3E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 PRINTS PR00834 HtrA/DegQ protease family signature 41 53 2.3E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 PRINTS PR00834 HtrA/DegQ protease family signature 139 156 2.3E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 Pfam PF13180 PDZ domain 201 283 9.3E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 Gene3D G3DSA:2.30.42.10 203 289 6.4E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 SUPERFAMILY SSF50156 178 288 6.84E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS03150 4356d8ad8e84b4fe92291502095bae6f 290 Pfam PF13365 Trypsin-like peptidase domain 33 168 3.7E-17 T 06-07-2017 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 SMART SM00342 186 269 8.1E-29 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 Pfam PF12833 Helix-turn-helix domain 192 269 1.0E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 253 6.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 269 6.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 Gene3D G3DSA:1.10.10.60 166 223 2.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 265 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 171 215 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 SUPERFAMILY SSF46689 222 269 1.75E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 Gene3D G3DSA:1.10.10.60 224 270 8.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 SUPERFAMILY SSF51215 32 104 1.31E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS17905 4cc58f36740c89f500a6f36821e22661 274 SUPERFAMILY SSF46689 169 220 1.52E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.30.420.40 314 356 5.2E-36 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.30.420.40 192 224 5.2E-36 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.30.420.40 119 191 3.9E-66 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.30.420.40 4 52 3.9E-66 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 SUPERFAMILY SSF100920 379 535 9.81E-62 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 SUPERFAMILY SSF53067 186 377 2.9E-69 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 329 345 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 464 480 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 383 402 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 360 380 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 PRINTS PR00301 70kDa heat shock protein signature 197 207 2.7E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Pfam PF00012 Hsp70 protein 4 599 6.3E-279 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:2.60.34.10 385 527 9.1E-73 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.90.640.10 225 309 7.2E-32 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 628 38.173 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 599 2.4E-302 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:3.30.30.30 53 108 1.1E-30 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 SUPERFAMILY SSF53067 4 184 3.08E-68 T 06-07-2017 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 SUPERFAMILY SSF100934 502 599 8.5E-23 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK95_RS08915 a69513ea4e0fc1324190fce713238520 638 Gene3D G3DSA:1.20.1270.10 528 598 7.6E-30 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAK95_RS19105 d7a124274a86afd35cc36bd822841b48 272 SUPERFAMILY SSF56300 4 236 5.63E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS19105 d7a124274a86afd35cc36bd822841b48 272 Gene3D G3DSA:3.60.21.10 3 231 1.1E-20 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS19105 d7a124274a86afd35cc36bd822841b48 272 Pfam PF00149 Calcineurin-like phosphoesterase 5 206 1.8E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS21835 1dcc1a8e967c14af3be480c5e852dba8 204 Gene3D G3DSA:3.30.1330.40 80 202 5.3E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS21835 1dcc1a8e967c14af3be480c5e852dba8 204 Pfam PF01042 Endoribonuclease L-PSP 83 200 1.0E-17 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS21835 1dcc1a8e967c14af3be480c5e852dba8 204 SUPERFAMILY SSF55298 83 201 2.2E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 Gene3D G3DSA:3.40.50.720 128 295 3.1E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 SMART SM00829 15 325 4.2E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 Pfam PF00107 Zinc-binding dehydrogenase 161 273 2.7E-14 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 Gene3D G3DSA:3.90.180.10 3 90 2.3E-9 T 06-07-2017 IPR011032 GroES-like CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 91 2.2E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 327 1.1E-135 T 06-07-2017 IPR014188 Acrylyl-CoA reductase AcuI CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 SUPERFAMILY SSF50129 4 148 8.18E-44 T 06-07-2017 IPR011032 GroES-like CAK95_RS00455 579ba11a3527e87e73b1a0d83c0c2980 328 SUPERFAMILY SSF51735 119 287 6.32E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 SMART SM00470 28 114 8.6E-10 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 SUPERFAMILY SSF53335 179 412 1.08E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 Pfam PF02195 ParB-like nuclease domain 32 113 2.0E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 Gene3D G3DSA:3.40.50.150 187 412 2.0E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 SUPERFAMILY SSF110849 27 157 8.37E-28 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 Pfam PF01555 DNA methylase 254 404 2.1E-15 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 346 363 2.6E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 365 383 2.6E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 210 224 2.6E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 388 408 2.6E-15 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 Gene3D G3DSA:3.90.1530.10 26 114 3.4E-13 T 06-07-2017 CAK95_RS03080 b1173c7c50d679e92b322aab0eb0b5e2 434 PIRSF PIRSF036758 25 426 6.4E-114 T 06-07-2017 IPR015840 DNA methyase, ParB domain-containing CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 SUPERFAMILY SSF88946 3 89 3.92E-19 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 Pfam PF04542 Sigma-70 region 2 8 73 1.7E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 SUPERFAMILY SSF88659 97 153 1.18E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 Pfam PF08281 Sigma-70, region 4 97 147 3.6E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 Gene3D G3DSA:1.10.10.10 96 154 2.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 152 2.3E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 29 59 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15875 2831ec809b7711adec6d6ebd5ccc19d5 163 Gene3D G3DSA:1.10.1740.10 3 92 3.5E-20 T 06-07-2017 CAK95_RS15550 4b439c8f7e0b52711a9a7684ccb3fc82 238 SMART SM00382 28 214 1.3E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15550 4b439c8f7e0b52711a9a7684ccb3fc82 238 Gene3D G3DSA:3.40.50.300 3 231 3.9E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15550 4b439c8f7e0b52711a9a7684ccb3fc82 238 Pfam PF00005 ABC transporter 20 163 9.9E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15550 4b439c8f7e0b52711a9a7684ccb3fc82 238 SUPERFAMILY SSF52540 3 235 1.88E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 413 433 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 298 319 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 65 85 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 378 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 331 355 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 398 413 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 23 46 1.6E-53 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 13 434 2.7E-119 T 06-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 Pfam PF13533 Biotin-lipoyl like 56 95 3.4E-6 T 06-07-2017 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 Gene3D G3DSA:2.40.50.100 56 87 4.3E-16 T 06-07-2017 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 Gene3D G3DSA:2.40.50.100 283 318 4.3E-16 T 06-07-2017 CAK95_RS09840 594735e4e10bad1aecb8546fef7209c1 434 Pfam PF13437 HlyD family secretion protein 286 388 4.1E-19 T 06-07-2017 CAK95_RS09505 e3c12279efc4cf4501d385a139367780 222 Pfam PF01738 Dienelactone hydrolase family 16 220 5.0E-47 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK95_RS09505 e3c12279efc4cf4501d385a139367780 222 SUPERFAMILY SSF53474 4 221 7.01E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09505 e3c12279efc4cf4501d385a139367780 222 Gene3D G3DSA:3.40.50.1820 5 222 2.8E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 SUPERFAMILY SSF56801 36 559 2.35E-78 T 06-07-2017 CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 224 235 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 Gene3D G3DSA:3.40.50.980 50 231 6.6E-22 T 06-07-2017 CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 Gene3D G3DSA:3.40.50.980 232 397 4.1E-22 T 06-07-2017 CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 Gene3D G3DSA:2.30.38.10 407 462 2.9E-10 T 06-07-2017 CAK95_RS06190 15bc8631f2623d2f91daa25d7570708b 627 Pfam PF00501 AMP-binding enzyme 58 462 1.1E-56 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS18085 4677fbd6e10b47eabe240636531c5751 168 Pfam PF05974 Domain of unknown function (DUF892) 10 167 2.5E-60 T 06-07-2017 IPR010287 Domain of unknown function DUF892 CAK95_RS18085 4677fbd6e10b47eabe240636531c5751 168 SUPERFAMILY SSF47240 2 159 1.3E-56 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS18085 4677fbd6e10b47eabe240636531c5751 168 Gene3D G3DSA:1.20.1260.10 3 167 5.1E-68 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS25530 a0a73870a548b70ea6e7f571ecc98c72 279 Gene3D G3DSA:3.30.465.10 59 175 1.6E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS25530 a0a73870a548b70ea6e7f571ecc98c72 279 Gene3D G3DSA:3.30.43.10 1 54 6.1E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS25530 a0a73870a548b70ea6e7f571ecc98c72 279 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 175 1.4E-38 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS25530 a0a73870a548b70ea6e7f571ecc98c72 279 SUPERFAMILY SSF56176 5 175 2.83E-42 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 48 70 7.3E-27 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 222 234 7.3E-27 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 189 211 7.3E-27 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 168 183 7.3E-27 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 Gene3D G3DSA:3.10.290.10 321 415 2.3E-24 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 SUPERFAMILY SSF52374 7 326 3.78E-97 T 06-07-2017 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 SUPERFAMILY SSF55174 317 415 2.47E-12 T 06-07-2017 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 6 416 43.017 T 06-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 Pfam PF00579 tRNA synthetases class I (W and Y) 34 327 7.7E-75 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 Gene3D G3DSA:1.10.240.10 239 320 7.9E-36 T 06-07-2017 CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 Gene3D G3DSA:3.40.50.620 3 238 1.5E-99 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS25035 10ce0e081efbd9288452a3a09058d8fd 417 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 7 414 9.5E-115 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 Pfam PF02540 NAD synthase 274 528 5.3E-75 T 06-07-2017 IPR022310 NAD/GMP synthase CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 SUPERFAMILY SSF56317 9 243 1.83E-56 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 SUPERFAMILY SSF52402 270 535 1.18E-73 T 06-07-2017 CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 Gene3D G3DSA:3.60.110.10 9 244 6.1E-54 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 Pfam PF00795 Carbon-nitrogen hydrolase 11 244 2.3E-24 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 Gene3D G3DSA:3.40.50.620 272 535 4.9E-72 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS19965 11e488f53422b926bee0851995bc8408 578 TIGRFAM TIGR00552 nadE: NAD+ synthetase 278 530 1.4E-62 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CAK95_RS15060 d9505671ffbbe9b4e44a7751668ca000 148 SUPERFAMILY SSF54637 2 146 9.64E-36 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15060 d9505671ffbbe9b4e44a7751668ca000 148 Gene3D G3DSA:3.10.129.10 2 146 1.7E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15060 d9505671ffbbe9b4e44a7751668ca000 148 Pfam PF01575 MaoC like domain 10 112 2.6E-21 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS15820 c888840e9de5268ce753707c412a87b5 309 Pfam PF06904 Extensin-like protein C-terminus 112 288 8.3E-44 T 06-07-2017 IPR009683 Extensin-like, C-terminal CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 481 6.4E-168 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 SUPERFAMILY SSF75304 1 482 6.28E-154 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 Pfam PF01425 Amidase 25 471 8.6E-150 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 92.292 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 ProSitePatterns PS00571 Amidases signature. 156 187 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK95_RS23805 8b54432c7255cce16568304f1f0b8365 491 Gene3D G3DSA:3.90.1300.10 2 483 2.9E-174 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 Pfam PF00925 GTP cyclohydrolase II 233 380 1.3E-22 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 29 224 2.2E-70 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 SUPERFAMILY SSF55821 30 231 2.52E-78 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 26 228 36.355 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 SUPERFAMILY SSF142695 229 382 2.88E-38 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 PIRSF PIRSF001259 26 385 6.7E-118 T 06-07-2017 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 33 223 9.9E-80 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS15895 ce9ca3d1ed9faad4fb7e0eafd61576ff 386 Gene3D G3DSA:3.90.870.10 27 235 3.4E-91 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK95_RS03935 1f3b8d3f80556fe44fe12fd4284cf415 303 Pfam PF13614 AAA domain 3 208 7.4E-37 T 06-07-2017 IPR025669 AAA domain CAK95_RS03935 1f3b8d3f80556fe44fe12fd4284cf415 303 SUPERFAMILY SSF52540 3 296 3.7E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03935 1f3b8d3f80556fe44fe12fd4284cf415 303 Gene3D G3DSA:3.40.50.300 2 296 4.4E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02215 5a08a7c83c5a8e52386581352ea4d7d9 415 Pfam PF04909 Amidohydrolase 125 398 5.5E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS02215 5a08a7c83c5a8e52386581352ea4d7d9 415 Gene3D G3DSA:3.20.20.140 45 399 1.3E-55 T 06-07-2017 CAK95_RS02215 5a08a7c83c5a8e52386581352ea4d7d9 415 SUPERFAMILY SSF51556 108 398 5.99E-59 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS02215 5a08a7c83c5a8e52386581352ea4d7d9 415 SUPERFAMILY SSF51556 43 70 5.99E-59 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 SUPERFAMILY SSF55781 103 277 1.77E-33 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 SUPERFAMILY SSF46785 31 104 3.62E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 Gene3D G3DSA:3.30.450.40 101 278 7.6E-35 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 Gene3D G3DSA:1.10.10.10 30 100 2.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 SMART SM00346 30 120 1.5E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 Pfam PF09339 IclR helix-turn-helix domain 32 82 1.2E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS11465 e6b3fd16a7af6a366c7af3c27d2768f5 297 Pfam PF01614 Bacterial transcriptional regulator 165 273 1.8E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 Gene3D G3DSA:3.40.190.10 90 190 2.8E-20 T 06-07-2017 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 SUPERFAMILY SSF53850 90 285 5.27E-31 T 06-07-2017 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 SUPERFAMILY SSF46785 4 113 1.19E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 Gene3D G3DSA:3.40.190.10 191 242 7.4E-7 T 06-07-2017 CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 Pfam PF03466 LysR substrate binding domain 90 281 3.7E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 Gene3D G3DSA:1.10.10.10 5 85 1.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05400 b4fb0d257b4997082e9a5d17480451a6 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.8E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS20615 094c125675e36ef7b8d078b345f1eec4 273 Gene3D G3DSA:3.90.260.10 161 257 2.8E-14 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS20615 094c125675e36ef7b8d078b345f1eec4 273 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 81 8.7E-22 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAK95_RS20615 094c125675e36ef7b8d078b345f1eec4 273 SMART SM00460 158 223 9.9E-17 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS20615 094c125675e36ef7b8d078b345f1eec4 273 Pfam PF01841 Transglutaminase-like superfamily 128 221 4.0E-23 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS20615 094c125675e36ef7b8d078b345f1eec4 273 SUPERFAMILY SSF54001 7 251 2.09E-42 T 06-07-2017 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Gene3D G3DSA:3.30.470.20 203 442 1.4E-95 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 SUPERFAMILY SSF52440 1 113 2.73E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.1E-43 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Gene3D G3DSA:3.30.1490.20 130 202 1.7E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 SUPERFAMILY SSF56059 83 346 2.12E-68 T 06-07-2017 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 3.3E-77 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Gene3D G3DSA:3.40.50.20 1 129 1.0E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 SMART SM00878 335 440 1.4E-63 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 6.1E-39 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 SUPERFAMILY SSF51246 331 443 9.42E-43 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS25250 ab0d839521cdc42358ec957898295ebd 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 1.2E-215 T 06-07-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CAK95_RS23815 2988bc134dcf475529b24b1a4d8cc507 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 1.8E-29 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK95_RS23815 2988bc134dcf475529b24b1a4d8cc507 95 SUPERFAMILY SSF141000 2 93 1.83E-29 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK95_RS23815 2988bc134dcf475529b24b1a4d8cc507 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.544 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK95_RS23815 2988bc134dcf475529b24b1a4d8cc507 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 90 1.4E-21 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK95_RS27015 be328e18c45d82662bdff8e6125b863a 373 SUPERFAMILY SSF53383 7 370 8.55E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS27015 be328e18c45d82662bdff8e6125b863a 373 Gene3D G3DSA:3.90.1150.10 257 362 5.1E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS27015 be328e18c45d82662bdff8e6125b863a 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216 225 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK95_RS27015 be328e18c45d82662bdff8e6125b863a 373 Gene3D G3DSA:3.40.640.10 39 256 1.2E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS27015 be328e18c45d82662bdff8e6125b863a 373 Pfam PF00155 Aminotransferase class I and II 22 362 1.0E-51 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS01300 706d3744899c5935eeb89b42d0f61c4b 220 Pfam PF04191 Phospholipid methyltransferase 84 152 2.1E-9 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS20590 27d58c023be770c67f12b479585faffe 417 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 208 415 2.3E-65 T 06-07-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CAK95_RS20590 27d58c023be770c67f12b479585faffe 417 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.2E-18 T 06-07-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CAK95_RS22155 9b16637dade8c82cf43982d355119bf1 91 SUPERFAMILY SSF55729 5 90 1.9E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS22155 9b16637dade8c82cf43982d355119bf1 91 Pfam PF14542 GCN5-related N-acetyl-transferase 13 89 9.9E-24 T 06-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CAK95_RS22155 9b16637dade8c82cf43982d355119bf1 91 Gene3D G3DSA:3.40.630.30 5 91 1.3E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 179 9.2E-51 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 SMART SM00861 4 179 1.2E-62 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 SUPERFAMILY SSF52518 2 203 2.3E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 Pfam PF02780 Transketolase, C-terminal domain 193 316 3.0E-37 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 Gene3D G3DSA:3.40.50.970 2 193 2.0E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 SUPERFAMILY SSF52922 191 324 2.22E-39 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS16825 0c8445beeba0c13db904c1203c325a27 326 Gene3D G3DSA:3.40.50.920 194 324 1.7E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 Gene3D G3DSA:1.10.630.10 4 399 7.9E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 Pfam PF00067 Cytochrome P450 209 369 1.5E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 192 214 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 136 152 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 273 284 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 291 318 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 319 334 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 340 349 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 89 100 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 153 168 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00359 B-class P450 signature 349 360 3.8E-50 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00385 P450 superfamily signature 238 255 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00385 P450 superfamily signature 273 284 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00385 P450 superfamily signature 349 360 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 PRINTS PR00385 P450 superfamily signature 340 349 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS25865 f52fbf0bb719fd51f36822651863d017 402 SUPERFAMILY SSF48264 10 399 3.14E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS14305 63836f84553afb3fdf4550e9aa08f767 485 SUPERFAMILY SSF53720 14 481 1.7E-131 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS14305 63836f84553afb3fdf4550e9aa08f767 485 Pfam PF00171 Aldehyde dehydrogenase family 31 476 3.2E-138 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS14305 63836f84553afb3fdf4550e9aa08f767 485 Gene3D G3DSA:3.40.605.10 23 269 8.7E-67 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS14305 63836f84553afb3fdf4550e9aa08f767 485 Gene3D G3DSA:3.40.309.10 270 453 3.9E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 SUPERFAMILY SSF161098 11 212 3.66E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Gene3D G3DSA:3.40.190.10 465 506 1.2E-36 T 06-07-2017 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Gene3D G3DSA:3.40.190.10 250 358 1.2E-36 T 06-07-2017 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Gene3D G3DSA:3.40.190.120 359 454 5.1E-27 T 06-07-2017 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 254 506 4.4E-48 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 SUPERFAMILY SSF53850 255 506 4.34E-51 T 06-07-2017 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Gene3D G3DSA:1.10.3720.10 12 220 2.6E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14730 5b1fb03f342b3e614515f4da211cdb8a 514 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 209 4.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10985 c0042634e743fac1010243749d875130 173 Pfam PF05239 PRC-barrel domain 65 139 1.0E-12 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS10985 c0042634e743fac1010243749d875130 173 SUPERFAMILY SSF50346 65 155 1.41E-15 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS10985 c0042634e743fac1010243749d875130 173 Gene3D G3DSA:2.30.30.240 64 119 5.9E-11 T 06-07-2017 CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 1.1E-5 T 06-07-2017 CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 6.4E-68 T 06-07-2017 CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 SUPERFAMILY SSF51735 6 244 3.91E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 243 7.2E-96 T 06-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 Gene3D G3DSA:3.40.50.720 1 244 4.7E-90 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25895 e6ef64a6aebfe417689d61aad02137aa 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 Gene3D G3DSA:3.40.50.2300 158 312 1.4E-21 T 06-07-2017 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 SUPERFAMILY SSF53822 32 391 5.38E-56 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 Gene3D G3DSA:3.40.50.2300 28 155 2.2E-23 T 06-07-2017 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 Gene3D G3DSA:3.40.50.2300 313 372 2.2E-23 T 06-07-2017 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 Pfam PF13458 Periplasmic binding protein 34 373 2.5E-47 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 2.4E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 2.4E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12225 1703be2969274a32a88ee0c71dea12e1 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 291 304 2.4E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS28180 b2892c5cdc9a9a8aaf5650370a8f0196 311 Gene3D G3DSA:3.40.190.10 114 214 5.4E-5 T 06-07-2017 CAK95_RS28180 b2892c5cdc9a9a8aaf5650370a8f0196 311 SUPERFAMILY SSF53850 94 266 1.05E-13 T 06-07-2017 CAK95_RS28180 b2892c5cdc9a9a8aaf5650370a8f0196 311 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 35 306 2.0E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28180 b2892c5cdc9a9a8aaf5650370a8f0196 311 PIRSF PIRSF017082 1 309 5.7E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 Gene3D G3DSA:1.10.530.10 601 743 1.2E-40 T 06-07-2017 CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 Gene3D G3DSA:1.25.20.10 129 494 1.6E-33 T 06-07-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 SUPERFAMILY SSF53955 601 741 2.85E-39 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 SUPERFAMILY SSF48435 124 576 4.84E-68 T 06-07-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 608 636 - T 06-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CAK95_RS05035 e393ca5bf08aaecc50733243714bf225 756 Pfam PF01464 Transglycosylase SLT domain 599 701 7.0E-26 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS12610 21af6d956bb5e4254489eab2fbe10015 554 SUPERFAMILY SSF111369 294 482 6.8E-6 T 06-07-2017 CAK95_RS22895 60205438c617ec1d8dcdd19023a2675c 476 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 464 6.6E-145 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAK95_RS22895 60205438c617ec1d8dcdd19023a2675c 476 Pfam PF00361 Proton-conducting membrane transporter 124 416 3.7E-83 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22895 60205438c617ec1d8dcdd19023a2675c 476 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 465 18.452 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAK95_RS27720 883f4fb92c503e8de3b049a2e1935ea3 362 Pfam PF09663 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) 5 361 7.4E-146 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAK95_RS27720 883f4fb92c503e8de3b049a2e1935ea3 362 TIGRFAM TIGR02714 amido_AtzD_TrzD: ring-opening amidohydrolases 5 361 9.7E-127 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 154 2.5E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 208 2.5E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 237 2.5E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 239 256 2.5E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 87 2.5E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 SUPERFAMILY SSF51735 70 309 1.59E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 218 237 2.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 198 206 2.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 154 2.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 205 233 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 Pfam PF00106 short chain dehydrogenase 70 258 3.2E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS26770 100fed4060a80665978fdae1cafdaba5 324 Gene3D G3DSA:3.40.50.720 70 312 5.0E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 Gene3D G3DSA:3.40.718.10 4 341 2.7E-118 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 SUPERFAMILY SSF53659 2 351 1.71E-119 T 06-07-2017 CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 352 9.8E-173 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 SMART SM01329 5 348 1.0E-181 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09560 95cc55efe319f1ed4e50c9d82ee21e58 355 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 348 2.3E-92 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS21980 bd87a0e3e1fa727832688867080d7eb2 244 Pfam PF03591 AzlC protein 29 168 1.7E-14 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease CAK95_RS11995 0c72b1abf4f7a155877929f96953d887 177 SUPERFAMILY SSF55961 26 175 1.9E-16 T 06-07-2017 CAK95_RS11995 0c72b1abf4f7a155877929f96953d887 177 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 31 175 3.6E-15 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK95_RS11995 0c72b1abf4f7a155877929f96953d887 177 Gene3D G3DSA:3.30.530.20 27 175 6.3E-10 T 06-07-2017 IPR023393 START-like domain CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 Pfam PF00043 Glutathione S-transferase, C-terminal domain 104 189 9.9E-14 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 SUPERFAMILY SSF47616 81 199 3.34E-32 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 Gene3D G3DSA:1.20.1050.10 90 188 3.9E-41 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 SUPERFAMILY SSF52833 1 85 1.47E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 7.4E-11 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS17485 635e8f4654aecdb0f4ae160f879977de 205 Gene3D G3DSA:3.40.30.10 1 89 9.9E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01635 a660dc635c0c003cd1276005bdfe4886 218 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 15 212 1.1E-42 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK95_RS01635 a660dc635c0c003cd1276005bdfe4886 218 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 65 87 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK95_RS01635 a660dc635c0c003cd1276005bdfe4886 218 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 87 1.8E-16 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK95_RS01635 a660dc635c0c003cd1276005bdfe4886 218 PIRSF PIRSF000847 12 218 2.8E-44 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 Gene3D G3DSA:3.40.50.150 3 135 1.0E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 Gene3D G3DSA:1.10.150.290 182 236 3.8E-26 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 Gene3D G3DSA:1.10.150.290 136 145 3.8E-26 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 Pfam PF13649 Methyltransferase domain 35 123 1.6E-18 T 06-07-2017 CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 SUPERFAMILY SSF53335 13 247 3.65E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01995 b43855fc1d8acd9cb2f590c064abd1aa 256 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 2 256 40.582 T 06-07-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS14655 2f522bf3829f18fa53aebcbf8fc94cd8 279 Gene3D G3DSA:3.40.50.1460 55 266 7.6E-17 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS14655 2f522bf3829f18fa53aebcbf8fc94cd8 279 Pfam PF00656 Caspase domain 57 269 7.3E-29 T 06-07-2017 CAK95_RS14655 2f522bf3829f18fa53aebcbf8fc94cd8 279 SUPERFAMILY SSF52129 23 278 2.39E-51 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS10680 c74cf9f4cc8cf74b48e10c928054bd5f 341 Pfam PF09084 NMT1/THI5 like 47 260 9.3E-43 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS10680 c74cf9f4cc8cf74b48e10c928054bd5f 341 SUPERFAMILY SSF53850 36 262 2.11E-29 T 06-07-2017 CAK95_RS10680 c74cf9f4cc8cf74b48e10c928054bd5f 341 Gene3D G3DSA:3.40.190.10 125 247 6.4E-8 T 06-07-2017 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 Gene3D G3DSA:3.50.50.60 273 326 4.4E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 Gene3D G3DSA:3.50.50.60 3 165 4.4E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 6.7E-5 T 06-07-2017 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.7E-5 T 06-07-2017 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 SUPERFAMILY SSF51905 281 354 1.01E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20510 694f50b2194d16534323c75ae90f3a07 402 SUPERFAMILY SSF51905 3 158 1.01E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06930 5c93e9b2ddbd45fd92edf0f00074bc7f 124 SUPERFAMILY SSF49503 7 120 7.16E-8 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS06930 5c93e9b2ddbd45fd92edf0f00074bc7f 124 Gene3D G3DSA:2.60.40.420 8 119 8.5E-6 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 Pfam PF01632 Ribosomal protein L35 2 60 2.5E-21 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.4E-13 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.4E-13 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.4E-13 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 61 2.4E-23 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.03 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK95_RS09035 1b6b8e912d5d854726a089463b95794b 66 SUPERFAMILY SSF143034 2 61 4.84E-20 T 06-07-2017 CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 SUPERFAMILY SSF50129 3 150 3.62E-35 T 06-07-2017 IPR011032 GroES-like CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 SUPERFAMILY SSF51735 118 274 1.1E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 Pfam PF00107 Zinc-binding dehydrogenase 158 271 9.7E-23 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 3.0E-7 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 Gene3D G3DSA:3.40.50.720 152 267 1.3E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 SMART SM00829 11 327 1.3E-23 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS23825 a70e049df68938f15060e1f3d426d2c7 329 Gene3D G3DSA:3.90.180.10 3 151 4.4E-39 T 06-07-2017 IPR011032 GroES-like CAK95_RS15600 a88ed9493f8b7d572495555eb14eafde 250 SUPERFAMILY SSF52540 18 248 4.26E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15600 a88ed9493f8b7d572495555eb14eafde 250 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS15600 a88ed9493f8b7d572495555eb14eafde 250 Pfam PF00005 ABC transporter 34 179 1.9E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15600 a88ed9493f8b7d572495555eb14eafde 250 SMART SM00382 43 228 9.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15600 a88ed9493f8b7d572495555eb14eafde 250 Gene3D G3DSA:3.40.50.300 17 241 1.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 SUPERFAMILY SSF55781 87 260 2.55E-40 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 Gene3D G3DSA:3.30.450.40 86 261 1.1E-45 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 SMART SM00346 18 106 9.9E-27 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 Pfam PF01614 Bacterial transcriptional regulator 134 258 4.5E-24 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 15 261 1.6E-91 T 06-07-2017 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 Gene3D G3DSA:1.10.10.10 11 77 4.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 Pfam PF09339 IclR helix-turn-helix domain 20 70 2.0E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS00950 64b750b7b6bcca4c5ee501603746574b 262 SUPERFAMILY SSF46785 18 89 1.85E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04475 4afe62d47b87e434bb52b4c78f5e0050 388 Pfam PF00535 Glycosyl transferase family 2 46 220 1.1E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS04475 4afe62d47b87e434bb52b4c78f5e0050 388 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 4 377 6.1E-149 T 06-07-2017 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB CAK95_RS04475 4afe62d47b87e434bb52b4c78f5e0050 388 Gene3D G3DSA:3.90.550.10 46 226 1.8E-19 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS04475 4afe62d47b87e434bb52b4c78f5e0050 388 SUPERFAMILY SSF53448 40 246 3.05E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS15005 4653b6add4632800e96b50aef3a39dc4 132 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 40 129 2.9E-22 T 06-07-2017 IPR030999 Sulfur oxidation c-type cytochrome SoxX CAK95_RS15005 4653b6add4632800e96b50aef3a39dc4 132 Pfam PF00034 Cytochrome c 31 130 3.5E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS15005 4653b6add4632800e96b50aef3a39dc4 132 Gene3D G3DSA:1.10.760.10 8 131 3.3E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS15005 4653b6add4632800e96b50aef3a39dc4 132 SUPERFAMILY SSF46626 7 130 1.86E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS17255 ca2579f369f7f39080e783c7effe850f 207 Pfam PF00174 Oxidoreductase molybdopterin binding domain 41 187 8.3E-29 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS17255 ca2579f369f7f39080e783c7effe850f 207 SUPERFAMILY SSF56524 19 206 2.75E-54 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS17255 ca2579f369f7f39080e783c7effe850f 207 Gene3D G3DSA:3.90.420.10 20 204 4.1E-44 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS28305 b437c57670f2abe8becf7d5e8290b42b 151 Gene3D G3DSA:3.10.129.10 9 149 7.5E-48 T 06-07-2017 IPR029069 HotDog domain CAK95_RS28305 b437c57670f2abe8becf7d5e8290b42b 151 Pfam PF03061 Thioesterase superfamily 34 116 1.2E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS28305 b437c57670f2abe8becf7d5e8290b42b 151 SUPERFAMILY SSF54637 15 148 7.15E-35 T 06-07-2017 IPR029069 HotDog domain CAK95_RS10020 81d1bee88e820338ccbf4057d28267a7 403 SUPERFAMILY SSF53822 36 388 2.36E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS10020 81d1bee88e820338ccbf4057d28267a7 403 Gene3D G3DSA:3.40.50.2300 32 158 2.3E-37 T 06-07-2017 CAK95_RS10020 81d1bee88e820338ccbf4057d28267a7 403 Gene3D G3DSA:3.40.50.2300 313 364 2.3E-37 T 06-07-2017 CAK95_RS10020 81d1bee88e820338ccbf4057d28267a7 403 Gene3D G3DSA:3.40.50.2300 161 312 9.9E-23 T 06-07-2017 CAK95_RS10020 81d1bee88e820338ccbf4057d28267a7 403 Pfam PF13458 Periplasmic binding protein 36 377 3.8E-70 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS11930 705aa85907ad0d6cb2f4a70ad46d1cd7 63 Pfam PF04588 Hypoxia induced protein conserved region 8 56 7.7E-13 T 06-07-2017 IPR007667 Hypoxia induced protein, domain CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 SUPERFAMILY SSF88946 4 105 1.22E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 Gene3D G3DSA:1.10.1740.10 3 110 1.7E-18 T 06-07-2017 CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 Pfam PF04542 Sigma-70 region 2 34 97 1.1E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 Pfam PF08281 Sigma-70, region 4 123 173 2.9E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 SUPERFAMILY SSF88659 115 177 7.85E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 Gene3D G3DSA:1.10.10.10 120 178 2.9E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02445 86043260cdfa516513dab11dcfe8e815 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 174 1.0E-17 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.9E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 2.9E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.9E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 Pfam PF00561 alpha/beta hydrolase fold 26 243 5.1E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 SUPERFAMILY SSF53474 2 256 1.88E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08800 fe5f3f1a0a474085ba98d105f90a6885 258 Gene3D G3DSA:3.40.50.1820 2 257 1.6E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22620 c7756f889a4b3a885db942a2411e514a 80 Pfam PF13586 Transposase DDE domain 22 69 3.6E-6 T 06-07-2017 IPR025668 Transposase DDE domain CAK95_RS22285 9d68f131bf6c9b4eaa02858f9762fad4 317 Gene3D G3DSA:3.20.20.140 30 304 7.6E-54 T 06-07-2017 CAK95_RS22285 9d68f131bf6c9b4eaa02858f9762fad4 317 SUPERFAMILY SSF51556 39 304 3.45E-44 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS22285 9d68f131bf6c9b4eaa02858f9762fad4 317 Pfam PF04909 Amidohydrolase 41 303 3.2E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS13840 2f2c1ed917488daf2f3357f088b3647b 109 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 106 5.1E-33 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAK95_RS13840 2f2c1ed917488daf2f3357f088b3647b 109 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 105 24.096 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAK95_RS13840 2f2c1ed917488daf2f3357f088b3647b 109 SUPERFAMILY SSF103481 6 105 5.62E-8 T 06-07-2017 CAK95_RS13210 81293f31ff5a26ba9c90b37aa8857028 354 Pfam PF00535 Glycosyl transferase family 2 25 187 2.5E-29 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS13210 81293f31ff5a26ba9c90b37aa8857028 354 SUPERFAMILY SSF53448 24 229 1.64E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS13210 81293f31ff5a26ba9c90b37aa8857028 354 Gene3D G3DSA:3.90.550.10 24 152 9.6E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 SUPERFAMILY SSF51905 268 349 2.85E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 SUPERFAMILY SSF51905 7 178 2.85E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 Pfam PF01494 FAD binding domain 8 345 8.3E-60 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 Gene3D G3DSA:3.30.9.10 329 345 1.6E-6 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 Gene3D G3DSA:3.30.9.10 171 274 1.6E-6 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 Gene3D G3DSA:3.50.50.60 279 319 2.3E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 Gene3D G3DSA:3.50.50.60 7 170 2.3E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 9.9E-32 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 9.9E-32 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 9.9E-32 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 9.9E-32 T 06-07-2017 CAK95_RS12345 80b9f2e525d34864a85c536079b09c34 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 9.9E-32 T 06-07-2017 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 Gene3D G3DSA:1.25.40.10 65 157 4.3E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 Gene3D G3DSA:1.25.40.10 158 231 2.8E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 SMART SM00028 139 172 0.012 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 SMART SM00028 71 104 72.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 SMART SM00028 173 206 52.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 SUPERFAMILY SSF48452 68 232 5.39E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 Pfam PF13432 Tetratricopeptide repeat 144 200 4.4E-5 T 06-07-2017 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 PIRSF PIRSF035836 1 267 1.2E-97 T 06-07-2017 IPR014596 Uncharacterised conserved protein UCP035836 CAK95_RS06685 c121fb4191195efeccd725234d9660d8 279 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 60 130 1.9E-8 T 06-07-2017 CAK95_RS03610 dd227ee2bdf1cf8e65e86c261f955d76 74 Gene3D G3DSA:2.40.440.10 1 74 1.7E-7 T 06-07-2017 CAK95_RS03610 dd227ee2bdf1cf8e65e86c261f955d76 74 SUPERFAMILY SSF141523 1 74 8.37E-7 T 06-07-2017 CAK95_RS27765 34f77f965c3b8ccf36bb355b11bea871 243 Gene3D G3DSA:3.40.50.300 4 234 9.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27765 34f77f965c3b8ccf36bb355b11bea871 243 SUPERFAMILY SSF52540 5 237 3.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27765 34f77f965c3b8ccf36bb355b11bea871 243 SMART SM00382 31 222 3.5E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27765 34f77f965c3b8ccf36bb355b11bea871 243 Pfam PF00005 ABC transporter 23 171 2.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27765 34f77f965c3b8ccf36bb355b11bea871 243 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82866 291 495 6.8E-40 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82714 183 264 9.81E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Gene3D G3DSA:3.30.2090.10 183 265 8.7E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82714 712 797 2.88E-16 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Gene3D G3DSA:3.30.70.1430 45 142 4.1E-22 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Pfam PF00873 AcrB/AcrD/AcrF family 8 1030 2.0E-237 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82866 795 1032 7.72E-49 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82693 45 128 3.66E-19 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 4 1033 0.0 T 06-07-2017 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Gene3D G3DSA:1.10.3850.10 272 496 1.1E-67 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Gene3D G3DSA:1.10.3850.10 803 1031 1.4E-53 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 Gene3D G3DSA:3.30.2090.10 713 800 8.1E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 5.9E-32 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82693 137 182 1.18E-18 T 06-07-2017 CAK95_RS19685 1b527d729832e7df60851db317a91dd3 1038 SUPERFAMILY SSF82693 268 325 1.18E-18 T 06-07-2017 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 28 490 8.9E-172 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 Gene3D G3DSA:3.60.120.10 19 492 2.2E-169 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 174 1.3E-31 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 PRINTS PR00095 Anthranilate synthase component I signature 330 343 1.0E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 PRINTS PR00095 Anthranilate synthase component I signature 439 453 1.0E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 PRINTS PR00095 Anthranilate synthase component I signature 344 357 1.0E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 PRINTS PR00095 Anthranilate synthase component I signature 424 438 1.0E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 Pfam PF00425 chorismate binding enzyme 230 482 3.1E-96 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK95_RS23105 10cf76a1f76d477f6d1f0916eeb3f5b4 504 SUPERFAMILY SSF56322 20 490 1.57E-155 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 Gene3D G3DSA:1.10.10.10 7 80 2.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 Gene3D G3DSA:3.40.190.10 168 258 3.5E-21 T 06-07-2017 CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 SUPERFAMILY SSF53850 93 294 1.99E-35 T 06-07-2017 CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 SUPERFAMILY SSF46785 7 111 2.17E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 Pfam PF03466 LysR substrate binding domain 94 289 7.0E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS26120 1cf9d775e712df69fe26de08580abdfb 299 Gene3D G3DSA:3.40.190.10 94 167 0.001 T 06-07-2017 CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 Gene3D G3DSA:3.40.30.10 1 89 1.6E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 11 79 3.6E-9 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 SUPERFAMILY SSF47616 81 196 2.09E-28 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 190 1.7E-15 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 SUPERFAMILY SSF52833 1 84 3.48E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS05445 7505717ec56f96ee6034c1735c815349 211 Gene3D G3DSA:1.20.1050.10 90 189 1.1E-35 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01275 08b3f0d593a8905cd8d6aacb10756398 389 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 74 232 3.3E-44 T 06-07-2017 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CAK95_RS01275 08b3f0d593a8905cd8d6aacb10756398 389 Gene3D G3DSA:2.60.120.330 134 234 3.8E-12 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK95_RS01275 08b3f0d593a8905cd8d6aacb10756398 389 SUPERFAMILY SSF51197 134 254 2.55E-13 T 06-07-2017 CAK95_RS09075 1876fdb8fb98432fbb65c1b83cf7baaf 266 Gene3D G3DSA:3.40.50.720 3 250 5.0E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09075 1876fdb8fb98432fbb65c1b83cf7baaf 266 Pfam PF00899 ThiF family 10 244 1.6E-57 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS09075 1876fdb8fb98432fbb65c1b83cf7baaf 266 SUPERFAMILY SSF69572 3 258 5.23E-77 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK95_RS22540 1af89721ccf6310502d6fd2e5fce8b9a 412 SUPERFAMILY SSF55729 212 342 2.54E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS22540 1af89721ccf6310502d6fd2e5fce8b9a 412 Pfam PF13480 Acetyltransferase (GNAT) domain 213 344 6.5E-23 T 06-07-2017 CAK95_RS09360 8be8fbc99c23c162e360ca4c9ef36152 437 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 428 1.1E-73 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS09360 8be8fbc99c23c162e360ca4c9ef36152 437 PIRSF PIRSF006066 5 437 4.1E-67 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Gene3D G3DSA:2.70.70.10 348 487 3.1E-46 T 06-07-2017 CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 SUPERFAMILY SSF51261 348 487 2.88E-51 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 SUPERFAMILY SSF54106 241 285 9.29E-8 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Pfam PF01551 Peptidase family M23 388 483 3.5E-32 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Gene3D G3DSA:3.10.350.10 241 286 4.3E-11 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Gene3D G3DSA:3.10.350.10 154 197 1.3E-10 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 SMART SM00257 152 196 1.0E-8 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 SMART SM00257 241 285 3.3E-7 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 SUPERFAMILY SSF54106 154 196 7.46E-7 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Pfam PF01476 LysM domain 242 285 1.6E-6 T 06-07-2017 IPR018392 LysM domain CAK95_RS23885 63826a2a21d0ab2be70be452700aaf9a 490 Pfam PF01476 LysM domain 154 196 3.8E-9 T 06-07-2017 IPR018392 LysM domain CAK95_RS28195 c0b63be8697232c13ef222c7ec7e0e8b 30 Pfam PF02560 Cyanate lyase C-terminal domain 1 25 1.9E-7 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28195 c0b63be8697232c13ef222c7ec7e0e8b 30 Gene3D G3DSA:3.30.1160.10 1 25 3.1E-7 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS28195 c0b63be8697232c13ef222c7ec7e0e8b 30 SUPERFAMILY SSF55234 1 25 2.22E-5 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 Gene3D G3DSA:1.25.10.10 267 317 9.7E-4 T 06-07-2017 IPR011989 Armadillo-like helical CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SUPERFAMILY SSF48371 70 310 5.15E-45 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 87 116 85.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 242 271 12.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 180 209 5.6 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 211 240 0.0019 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 56 85 29.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 25 54 110.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 273 302 0.041 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 149 178 0.029 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 SMART SM00567 E-Z type HEAT repeats 118 147 150.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 Pfam PF13646 HEAT repeats 232 314 2.3E-15 T 06-07-2017 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 Pfam PF13646 HEAT repeats 107 191 1.1E-15 T 06-07-2017 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 Pfam PF13646 HEAT repeats 20 96 1.3E-11 T 06-07-2017 CAK95_RS03750 34a77ee9e2bb96780cc9cba7aa12e972 320 Gene3D G3DSA:1.25.10.10 21 264 2.6E-49 T 06-07-2017 IPR011989 Armadillo-like helical CAK95_RS10430 2112b36912b7008bc342a9db51f5179a 293 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 156 176 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAK95_RS10430 2112b36912b7008bc342a9db51f5179a 293 SUPERFAMILY SSF56317 6 270 3.14E-81 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS10430 2112b36912b7008bc342a9db51f5179a 293 Pfam PF00795 Carbon-nitrogen hydrolase 9 262 2.5E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS10430 2112b36912b7008bc342a9db51f5179a 293 Gene3D G3DSA:3.60.110.10 5 279 1.4E-85 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 Gene3D G3DSA:3.40.50.620 202 251 7.6E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 Gene3D G3DSA:3.40.50.620 5 68 7.6E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 SUPERFAMILY SSF52374 5 286 8.7E-80 T 06-07-2017 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 Gene3D G3DSA:3.90.800.10 69 197 2.9E-16 T 06-07-2017 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 2.1E-16 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 2.1E-16 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 PRINTS PR00987 Glutamyl-tRNA synthetase signature 216 224 2.1E-16 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 2.1E-16 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 210 2.1E-16 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS11835 db248dce7d997ec43b0d3c788c7fe1c8 290 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 283 8.6E-48 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAK95_RS25440 ac623019b66fc63b46ab737b9d7ca635 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 283 1.7E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 275 301 1.2E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 122 167 1.2E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.90.1170.50 3 121 2.5E-33 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 675 4.8E-112 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 168 271 1.8E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 592 733 8.9E-56 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 351 431 8.9E-56 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 SUPERFAMILY SSF54665 4 146 4.32E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 19 133 6.2E-22 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 SMART SM01008 19 134 5.2E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 SUPERFAMILY SSF56003 126 732 2.62E-160 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS26220 cfa9a61b16686eb7a650a47e6e419683 733 Gene3D G3DSA:3.30.365.10 432 580 3.4E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 Gene3D G3DSA:1.20.1050.10 89 198 2.2E-22 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 SUPERFAMILY SSF47616 72 196 2.09E-23 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 Pfam PF00043 Glutathione S-transferase, C-terminal domain 120 192 1.0E-9 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 Gene3D G3DSA:3.40.30.10 2 88 6.2E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 SUPERFAMILY SSF52833 2 78 3.99E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS27210 038d96f7da32a9fd1570e7be015f2634 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 8 74 1.2E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Gene3D G3DSA:3.40.1190.10 96 319 1.0E-85 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 SUPERFAMILY SSF51984 9 94 5.49E-28 T 06-07-2017 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 SUPERFAMILY SSF53244 317 460 2.38E-49 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Gene3D G3DSA:3.40.50.720 9 95 4.5E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Gene3D G3DSA:3.90.190.20 320 463 2.3E-53 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Pfam PF01225 Mur ligase family, catalytic domain 10 106 2.1E-27 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 7 465 41.796 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 SUPERFAMILY SSF53623 93 316 3.27E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 10 456 8.3E-164 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Pfam PF08245 Mur ligase middle domain 112 298 1.9E-28 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS01785 f15f7d3a18b909f6402d98f895056d53 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 403 6.6E-21 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS08755 fd09dd9db2e2aa8a12b1b8e9f27f3abf 118 Pfam PF06803 Protein of unknown function (DUF1232) 58 92 1.3E-13 T 06-07-2017 IPR010652 Protein of unknown function DUF1232 CAK95_RS08755 fd09dd9db2e2aa8a12b1b8e9f27f3abf 118 PIRSF PIRSF031804 1 118 8.2E-45 T 06-07-2017 IPR016983 Uncharacterised conserved protein UCP031804 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 SUPERFAMILY SSF53850 91 296 6.7E-44 T 06-07-2017 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 Gene3D G3DSA:3.40.190.10 180 259 8.6E-8 T 06-07-2017 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 Gene3D G3DSA:1.10.10.10 3 83 7.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 SUPERFAMILY SSF46785 2 112 2.17E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 Gene3D G3DSA:3.40.190.10 94 179 1.9E-23 T 06-07-2017 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 Pfam PF03466 LysR substrate binding domain 90 291 4.1E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.2E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS06075 5b1b8ad250309fb5bdb0b9ba3ae54a93 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.7E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 SUPERFAMILY SSF46785 1 82 5.99E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 Pfam PF03466 LysR substrate binding domain 87 269 1.3E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 Gene3D G3DSA:3.40.190.10 81 191 2.5E-18 T 06-07-2017 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 Gene3D G3DSA:1.10.10.10 1 80 3.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 Gene3D G3DSA:3.40.190.10 192 260 8.4E-15 T 06-07-2017 CAK95_RS00470 a39265d6fbdfd3b11cc4405c95b1291a 316 SUPERFAMILY SSF53850 85 269 8.14E-29 T 06-07-2017 CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 Pfam PF08482 ATP-dependent helicase C-terminal 705 837 3.1E-51 T 06-07-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 Gene3D G3DSA:3.40.50.300 211 357 9.7E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 SMART SM00847 400 490 4.1E-18 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 10 848 0.0 T 06-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 SMART SM00487 5 193 7.0E-13 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 PIRSF PIRSF005496 5 851 0.0 T 06-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 SUPERFAMILY SSF52540 22 442 3.23E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 Gene3D G3DSA:3.40.50.300 10 168 2.0E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 SMART SM00490 233 340 1.7E-15 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 Pfam PF00271 Helicase conserved C-terminal domain 213 339 7.3E-12 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS06770 e609fbf2724d9620c061a7f170253e94 851 Pfam PF04408 Helicase associated domain (HA2) 401 457 2.2E-11 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 Pfam PF12697 Alpha/beta hydrolase family 43 280 2.1E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 3.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 3.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 3.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 Gene3D G3DSA:3.40.50.1820 37 286 2.3E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 SUPERFAMILY SSF53474 39 286 4.49E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00412 Epoxide hydrolase signature 47 65 4.2E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00412 Epoxide hydrolase signature 67 82 4.2E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS03685 d6369ca446d2bc2be2daf48f253ce5a8 313 PRINTS PR00412 Epoxide hydrolase signature 263 285 4.2E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 SUPERFAMILY SSF51395 7 301 1.63E-75 T 06-07-2017 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 324 50.522 T 06-07-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 Pfam PF01207 Dihydrouridine synthase (Dus) 11 302 1.7E-81 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 Gene3D G3DSA:3.20.20.70 8 241 8.1E-77 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 90 108 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 8 322 4.0E-135 T 06-07-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CAK95_RS19780 88d61eeb8634af1a04d3ed8638c67c57 335 PIRSF PIRSF006621 1 312 2.7E-74 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS02180 24df81d1b609be8f32735294f1b6aa36 337 Gene3D G3DSA:3.20.20.100 1 319 6.4E-89 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS02180 24df81d1b609be8f32735294f1b6aa36 337 SUPERFAMILY SSF51430 2 319 2.49E-89 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS02180 24df81d1b609be8f32735294f1b6aa36 337 PRINTS PR00069 Aldo-keto reductase signature 142 159 6.2E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS02180 24df81d1b609be8f32735294f1b6aa36 337 PRINTS PR00069 Aldo-keto reductase signature 111 129 6.2E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS02180 24df81d1b609be8f32735294f1b6aa36 337 Pfam PF00248 Aldo/keto reductase family 15 318 7.8E-68 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 466 9.5E-176 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 456 9.2E-41 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 1.4E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 Gene3D G3DSA:3.50.50.60 140 334 4.3E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 Gene3D G3DSA:3.50.50.60 2 139 6.4E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 SUPERFAMILY SSF51905 1 322 2.12E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.9E-39 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 7.9E-39 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 7.9E-39 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 7.9E-39 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 7.9E-39 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 SUPERFAMILY SSF55424 343 465 4.3E-43 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PIRSF PIRSF000350 1 465 7.0E-94 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.7E-79 T 06-07-2017 CAK95_RS07465 2ce9e11e6ab4079d0de807a6ea17b369 466 Gene3D G3DSA:3.30.390.30 335 465 1.5E-51 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 SUPERFAMILY SSF46785 27 101 1.63E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 Gene3D G3DSA:1.10.10.10 21 97 6.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 Pfam PF09339 IclR helix-turn-helix domain 29 79 3.8E-7 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 SMART SM00346 27 117 2.3E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 SUPERFAMILY SSF55781 93 267 9.81E-34 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 Gene3D G3DSA:3.30.450.40 101 269 2.3E-36 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS01415 47538bac8919ef897cc3d781934c6872 283 Pfam PF01614 Bacterial transcriptional regulator 147 264 3.6E-12 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS16615 6a34e101bbe0deaf60e889b6ebaf5a0f 389 Gene3D G3DSA:3.40.50.2300 198 336 1.5E-30 T 06-07-2017 CAK95_RS16615 6a34e101bbe0deaf60e889b6ebaf5a0f 389 Pfam PF02608 Basic membrane protein 81 336 1.2E-46 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CAK95_RS16615 6a34e101bbe0deaf60e889b6ebaf5a0f 389 Gene3D G3DSA:3.40.50.2300 82 197 3.4E-30 T 06-07-2017 CAK95_RS16615 6a34e101bbe0deaf60e889b6ebaf5a0f 389 SUPERFAMILY SSF53822 90 291 1.35E-13 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 240 3.9E-30 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 SMART SM00062 34 263 7.2E-57 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 Gene3D G3DSA:3.40.190.10 223 241 1.4E-20 T 06-07-2017 CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 Gene3D G3DSA:3.40.190.10 31 124 1.4E-20 T 06-07-2017 CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 Gene3D G3DSA:3.40.190.10 125 202 1.1E-12 T 06-07-2017 CAK95_RS24215 a280272c10e49db0bf14522952e0ad78 338 SUPERFAMILY SSF53850 25 253 3.74E-49 T 06-07-2017 CAK95_RS27440 1fdf2575062bf97005d4b1c4ed5b1c8b 153 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 26 118 2.2E-24 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS27440 1fdf2575062bf97005d4b1c4ed5b1c8b 153 SUPERFAMILY SSF51316 2 138 6.7E-42 T 06-07-2017 IPR011057 Mss4-like CAK95_RS27440 1fdf2575062bf97005d4b1c4ed5b1c8b 153 Gene3D G3DSA:3.90.1590.10 4 130 1.5E-35 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS19305 dd7618d68ffc6a3fee58f461e76544c0 259 SUPERFAMILY SSF52540 2 235 1.11E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19305 dd7618d68ffc6a3fee58f461e76544c0 259 Pfam PF00005 ABC transporter 23 177 3.8E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS19305 dd7618d68ffc6a3fee58f461e76544c0 259 Gene3D G3DSA:3.40.50.300 4 235 5.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19305 dd7618d68ffc6a3fee58f461e76544c0 259 SMART SM00382 31 228 1.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS19305 dd7618d68ffc6a3fee58f461e76544c0 259 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16145 862cc02480799efb53dbbb46f8382712 187 SUPERFAMILY SSF51182 75 148 1.94E-14 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS16145 862cc02480799efb53dbbb46f8382712 187 Gene3D G3DSA:2.60.120.10 72 148 1.1E-11 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS27175 d3a2b5ebbd9d8777bd9b371626a06273 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 43.377 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAK95_RS27175 d3a2b5ebbd9d8777bd9b371626a06273 209 Gene3D G3DSA:3.40.50.2020 4 209 6.4E-75 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS27175 d3a2b5ebbd9d8777bd9b371626a06273 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.1E-76 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAK95_RS27175 d3a2b5ebbd9d8777bd9b371626a06273 209 SUPERFAMILY SSF53271 4 207 2.62E-65 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS27175 d3a2b5ebbd9d8777bd9b371626a06273 209 Pfam PF14681 Uracil phosphoribosyltransferase 7 208 6.6E-66 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 PIRSF PIRSF002741 41 546 1.9E-66 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 Gene3D G3DSA:3.90.76.10 60 215 1.3E-30 T 06-07-2017 CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 435 6.6E-70 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 Gene3D G3DSA:3.40.190.10 216 321 4.3E-30 T 06-07-2017 CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 SUPERFAMILY SSF53850 55 548 1.74E-98 T 06-07-2017 CAK95_RS26720 b561544b88347748c558bbfbd0528f01 551 Gene3D G3DSA:3.10.105.10 322 521 5.5E-35 T 06-07-2017 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 1.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 SUPERFAMILY SSF48498 89 201 6.23E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 SUPERFAMILY SSF46689 19 75 3.59E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 Gene3D G3DSA:1.10.10.60 17 65 5.8E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 91 195 5.3E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS11645 1046bf4d2b96a94887d7083827c2dda7 202 Gene3D G3DSA:1.10.357.10 68 201 8.7E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 344 351 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 PRINTS PR00481 Cytosol aminopeptidase signature 340 360 2.8E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 PRINTS PR00481 Cytosol aminopeptidase signature 281 302 2.8E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 PRINTS PR00481 Cytosol aminopeptidase signature 318 339 2.8E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 PRINTS PR00481 Cytosol aminopeptidase signature 259 276 2.8E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 PRINTS PR00481 Cytosol aminopeptidase signature 369 384 2.8E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 488 4.4E-121 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 5 497 34.863 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 145 4.7E-19 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 Gene3D G3DSA:3.40.630.10 169 496 1.2E-133 T 06-07-2017 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 SUPERFAMILY SSF52949 12 182 1.59E-25 T 06-07-2017 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 Gene3D G3DSA:3.40.220.10 14 159 1.5E-25 T 06-07-2017 CAK95_RS25830 591854775db524c2d0b4f0c7f7ea257b 498 SUPERFAMILY SSF53187 178 495 3.3E-120 T 06-07-2017 CAK95_RS00775 de6ff8130060726c3480e41d92cbf9a6 380 SUPERFAMILY SSF111369 70 298 5.75E-24 T 06-07-2017 CAK95_RS00775 de6ff8130060726c3480e41d92cbf9a6 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 83 294 3.2E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS00775 de6ff8130060726c3480e41d92cbf9a6 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 375 5.4E-74 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS00775 de6ff8130060726c3480e41d92cbf9a6 380 Gene3D G3DSA:2.40.50.100 189 220 2.1E-14 T 06-07-2017 CAK95_RS00775 de6ff8130060726c3480e41d92cbf9a6 380 Gene3D G3DSA:2.40.50.100 85 114 2.1E-14 T 06-07-2017 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.927 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.9E-77 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 SUPERFAMILY SSF56053 1 82 1.25E-24 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 Gene3D G3DSA:3.90.930.12 83 177 9.3E-41 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 Gene3D G3DSA:3.90.930.12 2 82 1.1E-30 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 SUPERFAMILY SSF56053 83 177 3.27E-37 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 PIRSF PIRSF002162 1 177 5.1E-49 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.2E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.2E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.2E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 Pfam PF00347 Ribosomal protein L6 91 164 8.8E-22 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21340 1ce0ca26c8c5ddacacf90a647c1d6758 177 Pfam PF00347 Ribosomal protein L6 11 82 1.8E-17 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS06820 ba8cbc26dc878bd11b3397886218ba4f 168 Pfam PF08592 Domain of unknown function (DUF1772) 44 162 5.5E-7 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 Pfam PF03190 Protein of unknown function, DUF255 14 175 3.5E-73 T 06-07-2017 IPR004879 Domain of unknown function DUF255 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 SUPERFAMILY SSF48208 195 565 3.78E-66 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 Gene3D G3DSA:1.50.10.10 502 601 2.6E-4 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 Gene3D G3DSA:1.50.10.10 253 446 2.3E-9 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 Gene3D G3DSA:3.40.30.10 32 159 8.4E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 PIRSF PIRSF006402 2 704 2.2E-203 T 06-07-2017 IPR024705 Spermatogenesis-associated protein 20 CAK95_RS08125 93f13a06a21e193abbe5f14ed7fdbdeb 707 SUPERFAMILY SSF52833 13 152 1.93E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 Pfam PF00005 ABC transporter 25 167 1.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 SMART SM00382 34 217 1.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 SUPERFAMILY SSF52540 6 227 5.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 25 255 2.3E-103 T 06-07-2017 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 CAK95_RS17010 e8f13c849d4d808a3796ab4642c99061 265 Gene3D G3DSA:3.40.50.300 4 223 1.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09065 6391096eea2345f9838eeb6f32ea5819 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 3.1E-79 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS09065 6391096eea2345f9838eeb6f32ea5819 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS09065 6391096eea2345f9838eeb6f32ea5819 257 Gene3D G3DSA:3.90.226.10 1 254 2.6E-97 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS09065 6391096eea2345f9838eeb6f32ea5819 257 SUPERFAMILY SSF52096 1 256 2.34E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS27240 a675e45eb1785dcb687c5f7f4e1f4902 275 SMART SM00646 109 258 6.6E-4 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS27240 a675e45eb1785dcb687c5f7f4e1f4902 275 SUPERFAMILY SSF53187 47 261 8.16E-25 T 06-07-2017 CAK95_RS27240 a675e45eb1785dcb687c5f7f4e1f4902 275 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 49 258 7.2E-30 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS27240 a675e45eb1785dcb687c5f7f4e1f4902 275 Gene3D G3DSA:3.40.630.40 48 261 8.3E-28 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS09500 bf8ab56391bee96c80fc0bf830fc88c4 215 Gene3D G3DSA:3.10.560.10 133 210 6.0E-10 T 06-07-2017 CAK95_RS09500 bf8ab56391bee96c80fc0bf830fc88c4 215 Pfam PF02563 Polysaccharide biosynthesis/export protein 63 136 2.4E-18 T 06-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CAK95_RS09500 bf8ab56391bee96c80fc0bf830fc88c4 215 Gene3D G3DSA:3.30.1950.10 70 132 1.1E-16 T 06-07-2017 CAK95_RS09500 bf8ab56391bee96c80fc0bf830fc88c4 215 Pfam PF10531 SLBB domain 143 194 2.2E-10 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 SUPERFAMILY SSF56003 43 236 1.8E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Gene3D G3DSA:3.90.1170.50 198 249 7.9E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 SUPERFAMILY SSF56003 302 732 1.51E-109 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 SMART SM01008 203 280 2.4E-16 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 47 205 8.2E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 596 676 1.5E-17 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 303 592 3.3E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 PIRSF PIRSF036389 1 730 7.7E-196 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Gene3D G3DSA:3.30.365.10 548 733 4.8E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Gene3D G3DSA:3.30.365.10 375 547 9.4E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS18020 1cd25075f1d19bc99ce466b4bb8eb18f 735 Gene3D G3DSA:3.30.365.10 44 197 1.8E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16295 bfc71c4871cfc698ded4eb5d2c8c8c0c 248 Pfam PF07786 Protein of unknown function (DUF1624) 11 232 1.8E-66 T 06-07-2017 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 CAK95_RS25455 50182c849b8bc08852b2e40c28768996 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25455 50182c849b8bc08852b2e40c28768996 235 Gene3D G3DSA:3.40.50.300 1 221 4.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25455 50182c849b8bc08852b2e40c28768996 235 Pfam PF00005 ABC transporter 18 164 8.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS25455 50182c849b8bc08852b2e40c28768996 235 SUPERFAMILY SSF52540 2 222 7.34E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25455 50182c849b8bc08852b2e40c28768996 235 SMART SM00382 26 213 8.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10960 33e62fa8ae2254d94cec0269238a7d44 231 Gene3D G3DSA:3.20.20.70 3 212 3.2E-66 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS10960 33e62fa8ae2254d94cec0269238a7d44 231 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 213 38.902 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CAK95_RS10960 33e62fa8ae2254d94cec0269238a7d44 231 SUPERFAMILY SSF51366 3 211 2.67E-58 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS10960 33e62fa8ae2254d94cec0269238a7d44 231 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 208 3.5E-45 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CAK95_RS06315 e590a0b26943f70b331d02b40b44513c 268 Pfam PF01863 Protein of unknown function DUF45 41 240 1.4E-54 T 06-07-2017 IPR002725 Protein of unknown function DUF45 CAK95_RS13460 317a3ad8642edbe2cc0cc1724868592f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 1.0E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13460 317a3ad8642edbe2cc0cc1724868592f 328 PIRSF PIRSF017082 1 327 6.5E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13460 317a3ad8642edbe2cc0cc1724868592f 328 SUPERFAMILY SSF53850 116 289 2.71E-9 T 06-07-2017 CAK95_RS03660 7476d9d8eca1ab908425e3ae7a108da3 158 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 38 141 4.4E-24 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS03660 7476d9d8eca1ab908425e3ae7a108da3 158 Pfam PF05119 Phage terminase, small subunit 45 140 9.2E-27 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.90.1170.50 4 128 7.0E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 719 8.2E-178 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 464 633 1.5E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 SMART SM01008 20 140 1.5E-51 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 140 3.4E-24 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 SUPERFAMILY SSF56003 133 780 7.2E-204 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 188 293 1.3E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 634 780 3.3E-67 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 374 463 3.3E-67 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 SUPERFAMILY SSF54665 4 162 6.15E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 295 371 1.1E-45 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS20380 dc20c5962aa645869c86d6f878c66b1f 787 Gene3D G3DSA:3.30.365.10 129 187 1.1E-45 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06125 9cf577cb3d23b5b03ef00d20cb6cd101 423 SUPERFAMILY SSF53822 35 389 4.71E-68 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS06125 9cf577cb3d23b5b03ef00d20cb6cd101 423 Gene3D G3DSA:3.40.50.2300 34 238 7.2E-45 T 06-07-2017 CAK95_RS06125 9cf577cb3d23b5b03ef00d20cb6cd101 423 Pfam PF13458 Periplasmic binding protein 35 379 2.9E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.4E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 SUPERFAMILY SSF48498 77 192 4.45E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 Gene3D G3DSA:1.10.10.60 1 66 9.6E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 Gene3D G3DSA:1.10.357.10 72 192 5.6E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS07405 a26a5cc9e4c3e7274b182b5797a1f21f 210 SUPERFAMILY SSF46689 1 73 5.03E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 Gene3D G3DSA:3.10.25.10 203 307 2.0E-22 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 Pfam PF02911 Formyl transferase, C-terminal domain 202 297 2.7E-18 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 SUPERFAMILY SSF50486 202 304 9.1E-22 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 Pfam PF00551 Formyl transferase 1 160 3.2E-32 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 SUPERFAMILY SSF53328 1 197 1.31E-51 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS12760 f03b9f9140de79db19494b271d0b42e2 308 Gene3D G3DSA:3.40.50.170 1 197 4.3E-56 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK95_RS27030 a5c32b157bf6656b4782cd12ff5c80a3 166 Pfam PF05565 Siphovirus Gp157 10 155 2.6E-21 T 06-07-2017 IPR008840 Siphovirus Gp157 CAK95_RS09665 fbb2b9818f34b98207d8d5ee2162bc73 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 7.5E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS09665 fbb2b9818f34b98207d8d5ee2162bc73 255 Gene3D G3DSA:3.40.50.300 4 246 1.6E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09665 fbb2b9818f34b98207d8d5ee2162bc73 255 Pfam PF00005 ABC transporter 22 177 4.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09665 fbb2b9818f34b98207d8d5ee2162bc73 255 SUPERFAMILY SSF52540 5 247 3.69E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09665 fbb2b9818f34b98207d8d5ee2162bc73 255 SMART SM00382 30 224 1.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 SUPERFAMILY SSF50249 1 71 6.34E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 SMART SM00316 4 72 0.0026 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 24.728 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 5.8E-22 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.9E-28 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAK95_RS19995 82cce663e900b9be881637ba56682bcc 90 Gene3D G3DSA:2.40.50.140 1 71 3.6E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS18845 84e891e59ccea55b6e568c61c01967c8 131 ProDom PD102069 BLL3070 ATU0920 MEMBRANE AGR_C_1676P PRECURSOR TRANSMEMBRANE R01001 MLL7648 SIGNAL 1 93 3.0E-18 T 06-07-2017 CAK95_RS09735 da97d103aed8e112ab97ed5a619212af 481 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 6 479 5.1E-276 T 06-07-2017 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAK95_RS09735 da97d103aed8e112ab97ed5a619212af 481 Gene3D G3DSA:1.20.1260.10 104 265 3.4E-9 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS09735 da97d103aed8e112ab97ed5a619212af 481 SUPERFAMILY SSF47240 109 350 5.41E-48 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS06400 110075c08a7f9f2c8b660a53aa124d49 409 Gene3D G3DSA:3.30.1540.10 237 319 1.6E-24 T 06-07-2017 CAK95_RS06400 110075c08a7f9f2c8b660a53aa124d49 409 SUPERFAMILY SSF89796 18 391 5.89E-121 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS06400 110075c08a7f9f2c8b660a53aa124d49 409 Pfam PF02515 CoA-transferase family III 20 387 1.2E-116 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS06400 110075c08a7f9f2c8b660a53aa124d49 409 Gene3D G3DSA:3.40.50.10540 320 391 2.1E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS06400 110075c08a7f9f2c8b660a53aa124d49 409 Gene3D G3DSA:3.40.50.10540 16 230 2.1E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 SUPERFAMILY SSF51905 472 521 3.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 SUPERFAMILY SSF51905 8 190 3.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 SUPERFAMILY SSF51905 230 320 3.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 66 3.9E-5 T 06-07-2017 CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 Gene3D G3DSA:3.50.50.60 212 306 1.3E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15065 21584fc4c854300c8f803e88a47fb6b3 542 Gene3D G3DSA:3.50.50.60 4 76 1.3E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14395 7a3efbc099d9572d3fbfac22ac249281 410 Gene3D G3DSA:3.40.50.150 111 378 1.6E-89 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS14395 7a3efbc099d9572d3fbfac22ac249281 410 PIRSF PIRSF003085 3 397 4.2E-128 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK95_RS14395 7a3efbc099d9572d3fbfac22ac249281 410 Pfam PF02353 Mycolic acid cyclopropane synthetase 111 375 9.8E-85 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS14395 7a3efbc099d9572d3fbfac22ac249281 410 SUPERFAMILY SSF53335 118 379 5.73E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS18470 1ef0cc1ac788a31728ca3cba6fe631de 166 Gene3D G3DSA:1.10.10.10 6 144 2.9E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18470 1ef0cc1ac788a31728ca3cba6fe631de 166 Pfam PF01047 MarR family 37 95 4.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS18470 1ef0cc1ac788a31728ca3cba6fe631de 166 SMART SM00347 30 130 6.6E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS18470 1ef0cc1ac788a31728ca3cba6fe631de 166 SUPERFAMILY SSF46785 6 146 8.27E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 Gene3D G3DSA:1.10.10.10 2 83 3.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 3.0E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 Pfam PF03466 LysR substrate binding domain 92 287 4.2E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 Gene3D G3DSA:3.40.190.10 95 169 7.0E-21 T 06-07-2017 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 SUPERFAMILY SSF46785 8 113 3.49E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 SUPERFAMILY SSF53850 94 292 1.52E-31 T 06-07-2017 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26095 6c324c94592f032a3c351560ef777ad0 315 Gene3D G3DSA:3.40.190.10 170 236 7.8E-12 T 06-07-2017 CAK95_RS28510 2c049f7b5c9329a53576ecaa40d9eaa6 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 18 293 1.8E-46 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS28510 2c049f7b5c9329a53576ecaa40d9eaa6 308 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 16 307 2.8E-119 T 06-07-2017 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PIRSF PIRSF002560 1 157 6.9E-69 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 Gene3D G3DSA:1.20.1260.10 1 156 5.6E-64 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS28160 830d1a0129afc212943df24a82817019 160 Pfam PF00210 Ferritin-like domain 8 144 2.0E-40 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 SUPERFAMILY SSF47240 1 156 1.14E-53 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 86 106 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 23 43 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 107 127 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 65 85 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 128 149 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 44 64 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 PRINTS PR00601 Bacterioferritin signature 3 22 4.0E-61 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS28160 830d1a0129afc212943df24a82817019 160 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 2.3E-64 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 PIRSF PIRSF000139 6 426 1.4E-135 T 06-07-2017 IPR012257 Glycolate oxidase, iron-sulphur subunit CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 SUPERFAMILY SSF54862 23 118 1.72E-20 T 06-07-2017 CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 Pfam PF02754 Cysteine-rich domain 319 402 1.6E-11 T 06-07-2017 IPR004017 Cysteine-rich domain CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 Pfam PF02754 Cysteine-rich domain 186 272 6.5E-11 T 06-07-2017 IPR004017 Cysteine-rich domain CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 Pfam PF12838 4Fe-4S dicluster domain 24 90 4.4E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS13050 4d1ebc16d4625095df0de1f926e0987d 450 Gene3D G3DSA:1.10.1060.10 16 109 2.4E-21 T 06-07-2017 CAK95_RS00080 f40eb9bb19a073d6d399297c24ad127a 327 SUPERFAMILY SSF53850 117 285 5.43E-10 T 06-07-2017 CAK95_RS00080 f40eb9bb19a073d6d399297c24ad127a 327 Gene3D G3DSA:3.40.190.10 132 229 5.6E-6 T 06-07-2017 CAK95_RS00080 f40eb9bb19a073d6d399297c24ad127a 327 PIRSF PIRSF017082 5 327 2.7E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00080 f40eb9bb19a073d6d399297c24ad127a 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 9.8E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS28720 5569bc449e1b5cd43ddd132266f5cf73 392 Pfam PF13458 Periplasmic binding protein 32 368 1.2E-44 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS28720 5569bc449e1b5cd43ddd132266f5cf73 392 SUPERFAMILY SSF53822 31 375 2.36E-69 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS28720 5569bc449e1b5cd43ddd132266f5cf73 392 Gene3D G3DSA:3.40.50.2300 31 231 5.8E-41 T 06-07-2017 CAK95_RS02775 bda690a78d1189c152c242800fc5b808 252 Gene3D G3DSA:2.40.33.20 137 251 1.3E-7 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like CAK95_RS02775 bda690a78d1189c152c242800fc5b808 252 Pfam PF03476 MOSC N-terminal beta barrel domain 3 99 7.2E-9 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel CAK95_RS02775 bda690a78d1189c152c242800fc5b808 252 Pfam PF03473 MOSC domain 137 250 5.4E-20 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CAK95_RS02775 bda690a78d1189c152c242800fc5b808 252 SUPERFAMILY SSF50800 140 251 6.28E-34 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAK95_RS02775 bda690a78d1189c152c242800fc5b808 252 SUPERFAMILY SSF50800 1 51 6.28E-34 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAK95_RS20895 0a33612b7a9cbd6b624cbdfa89959ced 259 Gene3D G3DSA:3.40.50.10330 18 115 6.0E-17 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK95_RS20895 0a33612b7a9cbd6b624cbdfa89959ced 259 Pfam PF01513 ATP-NAD kinase 33 186 1.6E-15 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK95_RS20895 0a33612b7a9cbd6b624cbdfa89959ced 259 SUPERFAMILY SSF111331 31 245 2.62E-53 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK95_RS20895 0a33612b7a9cbd6b624cbdfa89959ced 259 Gene3D G3DSA:2.60.200.30 116 227 8.6E-28 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK95_RS20895 0a33612b7a9cbd6b624cbdfa89959ced 259 Hamap MF_00361 NAD kinase [nadK]. 8 259 20.853 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 SUPERFAMILY SSF53335 119 430 9.15E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 206 220 2.1E-25 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 235 245 2.1E-25 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 353 369 2.1E-25 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 414 431 2.1E-25 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 303 315 2.1E-25 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 Gene3D G3DSA:3.40.50.150 216 430 7.7E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 Gene3D G3DSA:3.30.70.1170 154 213 3.7E-7 T 06-07-2017 CAK95_RS26280 55667916d0231fb2ba79ca8a57aba36a 432 Pfam PF01189 16S rRNA methyltransferase RsmB/F 229 429 2.5E-41 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PRINTS PR01009 Flagellar M-ring protein signature 146 160 2.2E-33 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PRINTS PR01009 Flagellar M-ring protein signature 256 274 2.2E-33 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PRINTS PR01009 Flagellar M-ring protein signature 187 205 2.2E-33 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PRINTS PR01009 Flagellar M-ring protein signature 114 132 2.2E-33 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PRINTS PR01009 Flagellar M-ring protein signature 334 358 2.2E-33 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 5 545 1.3E-91 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 Pfam PF01514 Secretory protein of YscJ/FliF family 23 211 1.9E-65 T 06-07-2017 IPR006182 Secretory protein YscJ/FliF CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 PIRSF PIRSF004862 2 549 2.9E-134 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAK95_RS15350 68744488eb5ca632d5c6446e0d1e1fc1 549 Pfam PF08345 Flagellar M-ring protein C-terminal 245 410 7.1E-41 T 06-07-2017 IPR013556 Flagellar M-ring C-terminal CAK95_RS25200 f3b48430c6824257110823cb9f3f512a 352 SUPERFAMILY SSF53850 148 316 1.7E-7 T 06-07-2017 CAK95_RS25200 f3b48430c6824257110823cb9f3f512a 352 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 78 349 6.8E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25200 f3b48430c6824257110823cb9f3f512a 352 PIRSF PIRSF017082 25 352 2.9E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 SUPERFAMILY SSF56784 6 209 9.92E-33 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS26060 d12062ce179c241462118b935f600bba 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 5.5E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 5.5E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 5.5E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 169 182 5.5E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 10 171 8.6E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS26060 d12062ce179c241462118b935f600bba 212 Gene3D G3DSA:3.40.50.1000 6 204 8.1E-26 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS26060 d12062ce179c241462118b935f600bba 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 179 1.7E-11 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS17330 296e9fd46d338e4a33f1c0cb638c2be0 101 Pfam PF00699 Urease beta subunit 3 100 2.7E-48 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17330 296e9fd46d338e4a33f1c0cb638c2be0 101 Gene3D G3DSA:2.10.150.10 1 101 1.0E-53 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17330 296e9fd46d338e4a33f1c0cb638c2be0 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 100 9.2E-48 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17330 296e9fd46d338e4a33f1c0cb638c2be0 101 SUPERFAMILY SSF51278 1 101 9.16E-50 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17330 296e9fd46d338e4a33f1c0cb638c2be0 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 33.008 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 Gene3D G3DSA:3.40.30.10 2 85 9.3E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 SUPERFAMILY SSF47616 73 198 8.46E-38 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 Pfam PF00043 Glutathione S-transferase, C-terminal domain 107 191 5.0E-10 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 75 1.9E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 SUPERFAMILY SSF52833 1 82 6.65E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS18600 d5f37a4f3de914b2a2cfc582a8f47dc3 209 Gene3D G3DSA:1.20.1050.10 86 195 6.2E-49 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS16050 9007bd4f473da7a867d51f84c31e64c9 292 SUPERFAMILY SSF49482 1 285 1.7E-84 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS16050 9007bd4f473da7a867d51f84c31e64c9 292 Pfam PF00775 Dioxygenase 100 283 1.1E-42 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS16050 9007bd4f473da7a867d51f84c31e64c9 292 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 129 157 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS16050 9007bd4f473da7a867d51f84c31e64c9 292 Gene3D G3DSA:2.60.130.10 3 286 1.6E-87 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS16050 9007bd4f473da7a867d51f84c31e64c9 292 Pfam PF04444 Catechol dioxygenase N terminus 22 96 4.2E-32 T 06-07-2017 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 Gene3D G3DSA:2.30.30.60 653 701 2.1E-14 T 06-07-2017 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 SUPERFAMILY SSF50182 638 703 5.89E-15 T 06-07-2017 IPR010920 LSM domain CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 SUPERFAMILY SSF82861 552 636 9.68E-13 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 Pfam PF00924 Mechanosensitive ion channel 595 794 2.9E-52 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 Pfam PF12607 Protein of unknown function (DUF3772) 158 214 1.2E-13 T 06-07-2017 IPR022249 Domain of unknown function DUF3772 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 Gene3D G3DSA:3.30.70.100 709 792 1.6E-24 T 06-07-2017 CAK95_RS04755 622fc77dc764e7d9d4e9191856411228 831 SUPERFAMILY SSF82689 707 804 7.45E-29 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 Pfam PF07690 Major Facilitator Superfamily 26 418 1.1E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 508 9.6E-112 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 SUPERFAMILY SSF103473 23 210 9.16E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 SUPERFAMILY SSF103473 258 428 9.16E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 Gene3D G3DSA:1.20.1250.20 22 206 6.5E-27 T 06-07-2017 CAK95_RS15405 10345247a1a90164ab01d80bb9b6fada 533 Gene3D G3DSA:1.20.1250.20 273 429 4.6E-13 T 06-07-2017 CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 SUPERFAMILY SSF54909 64 152 2.01E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 Gene3D G3DSA:3.30.70.920 57 140 2.3E-31 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 Gene3D G3DSA:1.10.10.10 1 55 1.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 2.2E-18 T 06-07-2017 CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 SMART SM00344 4 113 2.0E-47 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 1.6E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 SUPERFAMILY SSF46785 3 94 9.12E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 4.8E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 4.8E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06615 068f75acba23c6a07e890f7005977e30 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 4.8E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 Gene3D G3DSA:1.20.120.530 84 219 5.8E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 Gene3D G3DSA:1.10.10.10 15 78 1.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 Pfam PF07729 FCD domain 90 217 1.2E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.4E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.4E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 SMART SM00345 22 81 2.0E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 71 3.7E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 SUPERFAMILY SSF46785 18 107 1.01E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 SUPERFAMILY SSF48008 87 220 5.75E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28810 23e501764c1969abb7fcab5d460dd5ed 229 SMART SM00895 90 219 1.9E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 SUPERFAMILY SSF54292 4 87 4.85E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 Pfam PF01799 [2Fe-2S] binding domain 72 143 2.1E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 52 1.0E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 SUPERFAMILY SSF47741 83 148 5.5E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 Gene3D G3DSA:1.10.150.120 74 148 3.4E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS15020 c9b3a476844f8c90e334da5758fd0797 149 Gene3D G3DSA:3.10.20.30 3 73 1.1E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 Gene3D G3DSA:3.40.190.10 179 265 1.8E-14 T 06-07-2017 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 SUPERFAMILY SSF46785 5 105 1.04E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 Gene3D G3DSA:1.10.10.10 4 84 2.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 SUPERFAMILY SSF53850 94 298 5.97E-23 T 06-07-2017 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 Gene3D G3DSA:3.40.190.10 93 178 5.4E-10 T 06-07-2017 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 4.2E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 Pfam PF03466 LysR substrate binding domain 92 297 1.1E-22 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02300 fc661f824ff9ef0297cd6e7b4a138bf5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 1.2E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.1E-16 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Gene3D G3DSA:2.40.30.10 302 395 6.0E-45 T 06-07-2017 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 SUPERFAMILY SSF52540 9 228 3.35E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 SUPERFAMILY SSF50447 205 303 1.96E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 SUPERFAMILY SSF50465 304 396 4.89E-35 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 4.6E-228 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Gene3D G3DSA:2.40.30.10 214 300 7.7E-38 T 06-07-2017 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Gene3D G3DSA:3.40.50.300 4 213 8.5E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 5.8E-33 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.0E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.0E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.0E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.0E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.0E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.088 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK95_RS21255 36cc3f6f537c3932b02d5b295af136b6 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.1E-57 T 06-07-2017 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 SUPERFAMILY SSF48498 90 207 3.2E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 Gene3D G3DSA:1.10.10.60 10 69 2.2E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 Gene3D G3DSA:1.10.357.10 70 207 3.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 Pfam PF13305 WHG domain 98 181 2.9E-15 T 06-07-2017 IPR025996 WHG domain CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04020 879a1cc70c2a9c3e67502caedabc9475 212 SUPERFAMILY SSF46689 12 86 1.15E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25650 6d593d97f4950fc6fa7663ff3d5bf435 531 SMART SM00052 252 497 4.1E-85 T 06-07-2017 IPR001633 EAL domain CAK95_RS25650 6d593d97f4950fc6fa7663ff3d5bf435 531 Pfam PF00563 EAL domain 258 492 8.8E-67 T 06-07-2017 IPR001633 EAL domain CAK95_RS25650 6d593d97f4950fc6fa7663ff3d5bf435 531 Gene3D G3DSA:3.20.20.450 258 503 8.4E-80 T 06-07-2017 IPR001633 EAL domain CAK95_RS25650 6d593d97f4950fc6fa7663ff3d5bf435 531 SUPERFAMILY SSF141868 259 503 3.01E-74 T 06-07-2017 IPR001633 EAL domain CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Gene3D G3DSA:3.30.470.30 287 392 4.9E-26 T 06-07-2017 CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Gene3D G3DSA:2.40.50.140 449 565 7.6E-38 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 165 1.4E-66 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 SUPERFAMILY SSF56091 259 445 3.36E-45 T 06-07-2017 CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Pfam PF13298 DNA polymerase Ligase (LigD) 39 144 6.9E-40 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Pfam PF01068 ATP dependent DNA ligase domain 276 445 1.4E-24 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 264 563 2.6E-95 T 06-07-2017 IPR014146 DNA ligase D, ligase domain CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 SUPERFAMILY SSF50249 450 565 1.37E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 620 864 7.6E-96 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Pfam PF04679 ATP dependent DNA ligase C terminal region 465 557 1.9E-21 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 273 891 8.7E-196 T 06-07-2017 IPR014143 DNA ligase D CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Gene3D G3DSA:3.30.1490.70 257 286 5.8E-18 T 06-07-2017 CAK95_RS22230 617a2d5e40522b37b6e547af972c9036 900 Gene3D G3DSA:3.30.1490.70 403 446 5.8E-18 T 06-07-2017 CAK95_RS08545 b31cdaac097b865054cd4012f2b1f845 64 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 11 64 27.826 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAK95_RS08545 b31cdaac097b865054cd4012f2b1f845 64 SUPERFAMILY SSF158997 11 64 2.22E-20 T 06-07-2017 CAK95_RS08545 b31cdaac097b865054cd4012f2b1f845 64 Pfam PF03966 Trm112p-like protein 12 51 2.4E-10 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAK95_RS08545 b31cdaac097b865054cd4012f2b1f845 64 Gene3D G3DSA:2.20.25.10 18 64 2.8E-25 T 06-07-2017 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 Gene3D G3DSA:3.10.20.30 3 73 4.3E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 Gene3D G3DSA:1.10.150.120 74 149 4.1E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 Pfam PF01799 [2Fe-2S] binding domain 72 143 2.2E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 64 8.9E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 SUPERFAMILY SSF47741 72 148 4.84E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS11550 9a1abd765d0ba2af8f72c58f30b220c2 150 SUPERFAMILY SSF54292 4 77 1.84E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS13060 fae94e3c1ff54e72bfc1f24b2df3d2ed 322 SUPERFAMILY SSF53850 29 249 9.12E-33 T 06-07-2017 CAK95_RS13060 fae94e3c1ff54e72bfc1f24b2df3d2ed 322 Pfam PF09084 NMT1/THI5 like 47 250 5.4E-23 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS13060 fae94e3c1ff54e72bfc1f24b2df3d2ed 322 SMART SM00062 28 249 0.0054 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS13060 fae94e3c1ff54e72bfc1f24b2df3d2ed 322 Gene3D G3DSA:3.40.190.10 115 238 2.4E-12 T 06-07-2017 CAK95_RS04155 55c1af8f892f19e72cf2e730fe99bf24 341 SUPERFAMILY SSF51569 4 339 3.87E-137 T 06-07-2017 CAK95_RS04155 55c1af8f892f19e72cf2e730fe99bf24 341 Gene3D G3DSA:3.20.20.70 5 334 5.3E-152 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS04155 55c1af8f892f19e72cf2e730fe99bf24 341 Pfam PF00274 Fructose-bisphosphate aldolase class-I 6 340 6.0E-146 T 06-07-2017 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 1.6E-64 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 SUPERFAMILY SSF48557 5 458 3.3E-144 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 449 7.4E-179 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Gene3D G3DSA:1.10.275.10 3 108 1.0E-39 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Gene3D G3DSA:1.20.200.10 109 376 3.0E-99 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Pfam PF00206 Lyase 8 302 6.4E-78 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Pfam PF14698 Argininosuccinate lyase C-terminal 365 434 1.3E-22 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Gene3D G3DSA:1.10.40.30 377 434 1.9E-26 T 06-07-2017 CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 1.5E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.5E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.5E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.5E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAK95_RS12070 33cfc70ebb75d23c93be5013deb9ff09 463 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 456 41.35 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK95_RS12665 4e7e83c980ca36396271b7ed63545221 158 Pfam PF09361 Phasin protein 51 148 4.1E-19 T 06-07-2017 IPR018968 Phasin CAK95_RS12665 4e7e83c980ca36396271b7ed63545221 158 TIGRFAM TIGR01985 phasin_2: phasin 30 150 3.4E-34 T 06-07-2017 IPR010234 Phasin, subfamily 2 CAK95_RS14700 8229f708c5deeb6d8b2f8bb4bb2bdc3d 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 296 1.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14700 8229f708c5deeb6d8b2f8bb4bb2bdc3d 299 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 31 293 1.3E-119 T 06-07-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CAK95_RS14700 8229f708c5deeb6d8b2f8bb4bb2bdc3d 299 SUPERFAMILY SSF161098 37 290 1.96E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14700 8229f708c5deeb6d8b2f8bb4bb2bdc3d 299 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 27 289 3.5E-91 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAK95_RS14700 8229f708c5deeb6d8b2f8bb4bb2bdc3d 299 Gene3D G3DSA:1.10.3720.10 39 292 6.7E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 98 3.5E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 SUPERFAMILY SSF47616 102 231 1.18E-30 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 SUPERFAMILY SSF52833 11 102 3.99E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 Gene3D G3DSA:3.40.30.10 8 101 4.9E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 Gene3D G3DSA:1.20.1050.10 102 226 4.8E-36 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS06785 bddb8bf22245badaec0f30101a8add3b 234 Pfam PF00043 Glutathione S-transferase, C-terminal domain 134 222 4.4E-8 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 22 405 1.9E-155 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 Pfam PF03781 Sulfatase-modifying factor enzyme 1 190 327 1.3E-25 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 Gene3D G3DSA:3.90.1580.10 332 405 1.6E-15 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 Gene3D G3DSA:3.90.1580.10 187 327 2.8E-38 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 SUPERFAMILY SSF56436 192 405 1.51E-64 T 06-07-2017 IPR016187 C-type lectin fold CAK95_RS00205 bb9638706d955cbe8c84001ed3bfe3b0 408 Pfam PF12867 DinB superfamily 25 159 8.1E-10 T 06-07-2017 IPR024775 DinB-like domain CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 Gene3D G3DSA:3.40.190.10 88 227 1.1E-24 T 06-07-2017 CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 Pfam PF03466 LysR substrate binding domain 88 292 8.6E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 SUPERFAMILY SSF46785 1 85 1.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 Gene3D G3DSA:1.10.10.10 1 82 8.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00785 92ff540a714dbb4b53fb135bbdff7820 307 SUPERFAMILY SSF53850 89 293 1.63E-37 T 06-07-2017 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Gene3D G3DSA:4.10.320.10 154 200 4.5E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Pfam PF00364 Biotin-requiring enzyme 2 74 3.0E-19 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Gene3D G3DSA:2.40.50.100 2 93 5.7E-30 T 06-07-2017 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Pfam PF02817 e3 binding domain 156 189 5.5E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 SUPERFAMILY SSF52777 218 449 9.34E-77 T 06-07-2017 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 3 449 2.2E-135 T 06-07-2017 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 SUPERFAMILY SSF51230 2 93 2.62E-26 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 448 2.3E-78 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 SUPERFAMILY SSF47005 154 192 1.44E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK95_RS16830 97ce30c5487b8f73b3fdbe47185276c2 450 Gene3D G3DSA:3.30.559.10 219 449 3.9E-81 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 Pfam PF00672 HAMP domain 177 245 1.4E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 Gene3D G3DSA:1.10.287.130 239 293 2.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 SMART SM00388 249 307 7.4E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 Gene3D G3DSA:3.30.565.10 294 454 3.8E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 1.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 452 3.5E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 SUPERFAMILY SSF55874 308 453 1.83E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 SMART SM00304 196 248 1.4E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 SUPERFAMILY SSF47384 233 305 1.84E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS03575 5c91ce427ac2c8de7fd368f72aa5a737 456 SMART SM00387 346 455 9.5E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05520 d22c4a00adae8843f2c482dba6716a76 192 SUPERFAMILY SSF55729 14 189 2.71E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS05520 d22c4a00adae8843f2c482dba6716a76 192 Gene3D G3DSA:3.40.630.30 12 189 1.7E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS05520 d22c4a00adae8843f2c482dba6716a76 192 Pfam PF13302 Acetyltransferase (GNAT) domain 22 165 2.3E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 SUPERFAMILY SSF52540 353 601 8.15E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 SMART SM00382 390 576 2.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 Gene3D G3DSA:1.20.1560.10 35 344 1.1E-81 T 06-07-2017 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 Pfam PF00664 ABC transporter transmembrane region 47 311 2.8E-52 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 Pfam PF00005 ABC transporter 381 530 2.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 SUPERFAMILY SSF90123 33 349 1.44E-77 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 28 601 2.2E-265 T 06-07-2017 IPR011918 ABC transporter, ATP-binding/permease protein CAK95_RS04210 ac14a06b6066039a6b48b172c4423b29 604 Gene3D G3DSA:3.40.50.300 363 594 1.4E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 331 4.8E-27 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 173 6.7E-54 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 534 6.3E-43 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 SUPERFAMILY SSF52518 8 183 1.45E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Gene3D G3DSA:3.40.50.970 8 182 5.1E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 SUPERFAMILY SSF52518 368 545 1.97E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Gene3D G3DSA:3.40.50.970 364 544 9.2E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 Gene3D G3DSA:3.40.50.1220 188 334 1.1E-34 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS03895 2f97700bfda52a299c4c73bf93f33eb3 559 SUPERFAMILY SSF52467 159 356 2.57E-36 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PIRSF PIRSF002869 1 506 3.0E-137 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 31 50 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 155 176 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 406 423 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 354 373 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 131 155 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 256 282 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 PRINTS PR01806 Virulence factor MviN signature 50 66 2.2E-69 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 495 7.5E-123 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS17785 ae4c61e02d01aeb45811b13c8730b121 526 Pfam PF03023 MviN-like protein 26 464 2.6E-113 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 PIRSF PIRSF036400 1 262 2.2E-124 T 06-07-2017 IPR014605 Signal transduction response regulator PhyR-like, alphaproteobacteria CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 SUPERFAMILY SSF52172 139 254 5.83E-22 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 Gene3D G3DSA:3.40.50.2300 138 259 1.7E-21 T 06-07-2017 CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 Pfam PF00072 Response regulator receiver domain 140 241 3.1E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 Pfam PF08281 Sigma-70, region 4 84 124 5.1E-6 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 Gene3D G3DSA:1.10.10.10 85 133 1.6E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 SMART SM00448 138 248 3.1E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS11080 0ebbf7a1fd90f9a64bb3509e3837bccd 266 SUPERFAMILY SSF88659 82 126 1.0E-5 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Pfam PF00501 AMP-binding enzyme 47 441 1.7E-80 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 36 536 1.5E-114 T 06-07-2017 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Gene3D G3DSA:3.40.50.980 40 205 2.4E-34 T 06-07-2017 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Gene3D G3DSA:2.30.38.10 364 431 5.2E-13 T 06-07-2017 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 528 2.0E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Gene3D G3DSA:3.40.50.980 206 363 2.3E-34 T 06-07-2017 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 Gene3D G3DSA:3.30.300.30 436 538 1.2E-28 T 06-07-2017 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 SUPERFAMILY SSF56801 26 540 2.35E-133 T 06-07-2017 CAK95_RS09930 28ee9d6e8368f047210b2a9624b3d12b 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS26570 44a7108dbbfe57760e90f6b08eaccf6d 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 335 2.8E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26570 44a7108dbbfe57760e90f6b08eaccf6d 339 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 114 - T 06-07-2017 IPR010916 TonB box, conserved site CAK95_RS26570 44a7108dbbfe57760e90f6b08eaccf6d 339 PIRSF PIRSF017082 15 339 2.3E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26570 44a7108dbbfe57760e90f6b08eaccf6d 339 SUPERFAMILY SSF53850 132 299 1.01E-9 T 06-07-2017 CAK95_RS08045 1b8dd8f5bae5f36f6bf15a8eb748625d 161 Pfam PF04186 FxsA cytoplasmic membrane protein 16 116 4.9E-21 T 06-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CAK95_RS06470 9c924af1e244444bff4c04b9bd284658 134 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 93 6.3E-23 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAK95_RS06470 9c924af1e244444bff4c04b9bd284658 134 Pfam PF03334 Na+/H+ antiporter subunit 12 92 1.9E-23 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAK95_RS22195 a97da6c2201bf462b5e3efe81206fdb8 182 SUPERFAMILY SSF53927 94 176 4.07E-37 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS22195 a97da6c2201bf462b5e3efe81206fdb8 182 SUPERFAMILY SSF53927 1 67 4.07E-37 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS22195 a97da6c2201bf462b5e3efe81206fdb8 182 Gene3D G3DSA:3.40.140.10 1 175 7.7E-43 T 06-07-2017 CAK95_RS22195 a97da6c2201bf462b5e3efe81206fdb8 182 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 126 1.1E-16 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 339 415 2.1E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 169 231 2.1E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 SMART SM01008 62 180 1.1E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 SUPERFAMILY SSF56003 172 815 8.37E-165 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 510 642 8.8E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 232 337 1.4E-23 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 SUPERFAMILY SSF54665 47 203 1.83E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 664 814 2.9E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.30.365.10 418 509 2.9E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 220 750 4.4E-137 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Gene3D G3DSA:3.90.1170.50 53 168 4.2E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS06530 7772a09dbe94a7ac5ee6ad39c562d880 818 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 63 180 3.4E-27 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS21420 8c7d305433a72d293427abdbf8567b6b 523 Gene3D G3DSA:1.20.1250.20 13 202 8.0E-8 T 06-07-2017 CAK95_RS21420 8c7d305433a72d293427abdbf8567b6b 523 SUPERFAMILY SSF53335 243 472 1.88E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS21420 8c7d305433a72d293427abdbf8567b6b 523 SUPERFAMILY SSF103473 13 207 6.02E-6 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS21420 8c7d305433a72d293427abdbf8567b6b 523 Gene3D G3DSA:3.40.50.150 251 511 6.3E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS21420 8c7d305433a72d293427abdbf8567b6b 523 Pfam PF01564 Spermine/spermidine synthase 302 415 6.8E-9 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 SUPERFAMILY SSF53706 12 581 9.29E-144 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Gene3D G3DSA:2.40.40.20 559 695 1.7E-27 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Gene3D G3DSA:3.40.50.740 323 540 1.2E-27 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Gene3D G3DSA:3.40.50.740 69 119 1.6E-11 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 SMART SM00926 8 64 5.6E-15 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 64 1.1E-7 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Pfam PF01568 Molydopterin dinucleotide binding domain 580 684 1.1E-20 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Gene3D G3DSA:3.40.228.10 154 322 1.2E-47 T 06-07-2017 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Pfam PF00384 Molybdopterin oxidoreductase 67 478 8.6E-57 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 SUPERFAMILY SSF50692 571 694 4.29E-31 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS25765 556a027040f3eebacffebd53bdad7966 697 Gene3D G3DSA:2.20.25.90 10 68 8.2E-13 T 06-07-2017 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 SUPERFAMILY SSF55681 24 230 2.32E-63 T 06-07-2017 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 91 137 2.0E-16 T 06-07-2017 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 Pfam PF03099 Biotin/lipoate A/B protein ligase family 82 183 2.5E-6 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 Gene3D G3DSA:3.90.1550.10 23 229 2.3E-65 T 06-07-2017 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 87 102 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 PIRSF PIRSF016262 21 242 2.4E-52 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 Hamap MF_00013 Octanoyltransferase [lipB]. 21 232 34.337 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS21710 5303057dd9f5c0838b2b20493298dd38 247 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 54 200 2.9E-43 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK95_RS23985 118433b804a198669494e00463c88f4e 144 Gene3D G3DSA:3.30.70.1060 1 117 4.3E-39 T 06-07-2017 CAK95_RS23985 118433b804a198669494e00463c88f4e 144 SUPERFAMILY SSF54909 1 117 5.36E-36 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS23985 118433b804a198669494e00463c88f4e 144 Pfam PF03795 YCII-related domain 1 114 1.3E-24 T 06-07-2017 IPR005545 YCII-related CAK95_RS12085 190ffb496dcaff389c7335ad37099687 866 TIGRFAM TIGR02302 aProt_lowcomp: TIGR02302 family protein 25 865 1.6E-287 T 06-07-2017 IPR012683 Conserved hypothetical protein CHP02302, transmembrane CAK95_RS12085 190ffb496dcaff389c7335ad37099687 866 Pfam PF13779 Domain of unknown function (DUF4175) 38 864 1.3E-297 T 06-07-2017 IPR012683 Conserved hypothetical protein CHP02302, transmembrane CAK95_RS11440 bdb567fd3fed1c6e29b0676eea5bec27 157 Pfam PF11578 Protein of unknown function (DUF3237) 6 156 3.3E-38 T 06-07-2017 IPR020915 Uncharacterised protein family UPF0311 CAK95_RS11440 bdb567fd3fed1c6e29b0676eea5bec27 157 Gene3D G3DSA:2.40.160.20 3 156 4.2E-42 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS07595 4366af17d20d6b1d0f3d878aa95fa32b 193 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 16 190 1.6E-52 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAK95_RS07595 4366af17d20d6b1d0f3d878aa95fa32b 193 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 16 190 18.064 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAK95_RS07595 4366af17d20d6b1d0f3d878aa95fa32b 193 Pfam PF04279 Intracellular septation protein A 16 188 3.8E-56 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 Gene3D G3DSA:1.20.1050.10 100 228 5.0E-35 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 76 9.3E-9 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 Gene3D G3DSA:3.40.30.10 1 99 6.6E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 133 208 1.1E-7 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 SUPERFAMILY SSF47616 70 226 7.25E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS05280 79ab833cc7869ac2a622de79c7f9cec3 232 SUPERFAMILY SSF52833 1 109 3.2E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 SUPERFAMILY SSF50156 94 188 1.25E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Gene3D G3DSA:3.30.750.44 51 110 1.1E-9 T 06-07-2017 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Gene3D G3DSA:2.30.42.10 111 187 3.1E-27 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 57 373 2.1E-104 T 06-07-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Pfam PF13180 PDZ domain 105 184 1.1E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 SMART SM00228 105 176 4.0E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 SMART SM00245 178 372 5.6E-81 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Pfam PF03572 Peptidase family S41 203 371 2.3E-57 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 SUPERFAMILY SSF52096 197 380 8.12E-85 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 SUPERFAMILY SSF52096 37 123 8.12E-85 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Gene3D G3DSA:3.90.226.10 188 374 1.5E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07345 f68df84b0d6df1846f821797701e9121 447 Gene3D G3DSA:3.90.226.10 408 432 1.5E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11375 a561779793e1dbbff4149b224e91511e 278 Gene3D G3DSA:3.10.180.10 132 264 5.9E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS11375 a561779793e1dbbff4149b224e91511e 278 SUPERFAMILY SSF54593 132 260 2.26E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS11375 a561779793e1dbbff4149b224e91511e 278 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 132 246 5.2E-19 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS11375 a561779793e1dbbff4149b224e91511e 278 Gene3D G3DSA:3.10.180.10 11 116 1.8E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS11375 a561779793e1dbbff4149b224e91511e 278 SUPERFAMILY SSF54593 12 116 2.02E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 912 919 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:1.10.1030.10 455 591 3.4E-47 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1142 13.264 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.40.50.20 3 108 6.6E-45 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.40.50.20 592 727 3.4E-57 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.30.1490.20 751 823 7.6E-20 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF52335 1008 1144 7.06E-39 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 208 388 1.2E-62 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 738 948 8.3E-30 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.30.470.20 824 1005 3.9E-69 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.30.470.20 255 454 8.9E-78 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SMART SM00851 1028 1114 1.3E-29 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF56059 197 455 1.18E-98 T 06-07-2017 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.40.50.1380 1010 1143 3.1E-39 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SMART SM01096 480 602 2.9E-70 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1134 13.049 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 774 788 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF52440 1 127 6.91E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 631 645 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 778 790 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 857 874 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 660 670 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 985 1003 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 912 941 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 823 842 5.6E-32 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Pfam PF02142 MGS-like domain 1031 1114 2.2E-17 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Gene3D G3DSA:3.30.1490.20 208 254 4.8E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 351 358 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 184 1123 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 483 602 2.6E-39 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF48108 450 604 4.18E-47 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF52440 618 740 1.58E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13795 697ea20da16b6291b904e1612038d938 1147 SUPERFAMILY SSF56059 738 1005 6.19E-96 T 06-07-2017 CAK95_RS24735 0b217b9ba511881102f3703680b9cb8a 288 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS24735 0b217b9ba511881102f3703680b9cb8a 288 Pfam PF00005 ABC transporter 41 180 9.8E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS24735 0b217b9ba511881102f3703680b9cb8a 288 SUPERFAMILY SSF52540 21 248 9.21E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24735 0b217b9ba511881102f3703680b9cb8a 288 Gene3D G3DSA:3.40.50.300 13 233 7.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24735 0b217b9ba511881102f3703680b9cb8a 288 SMART SM00382 49 242 7.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28140 9e286e4a99fd8f41f2b5dd2ee1d7b51d 390 SUPERFAMILY SSF53383 10 379 1.51E-73 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS28140 9e286e4a99fd8f41f2b5dd2ee1d7b51d 390 Gene3D G3DSA:3.40.640.10 22 265 2.0E-49 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS28140 9e286e4a99fd8f41f2b5dd2ee1d7b51d 390 PIRSF PIRSF000525 10 383 8.0E-57 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAK95_RS28140 9e286e4a99fd8f41f2b5dd2ee1d7b51d 390 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 9 381 3.3E-203 T 06-07-2017 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CAK95_RS28140 9e286e4a99fd8f41f2b5dd2ee1d7b51d 390 Pfam PF00266 Aminotransferase class-V 132 254 4.4E-5 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS01555 7ae6babb6654600828099cc1fdcef8bd 172 Gene3D G3DSA:3.10.180.10 14 139 7.6E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS01555 7ae6babb6654600828099cc1fdcef8bd 172 SUPERFAMILY SSF54593 11 148 8.6E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS01555 7ae6babb6654600828099cc1fdcef8bd 172 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 139 1.5E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 7 61 3.1E-23 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 Pfam PF00327 Ribosomal protein L30p/L7e 7 57 1.2E-14 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 4 61 17.532 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 SUPERFAMILY SSF55129 5 61 1.2E-17 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 Gene3D G3DSA:3.30.1390.20 5 61 1.8E-26 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK95_RS21355 dc1dcc9d0a3b7024797e67241e998282 63 PIRSF PIRSF002211 1 63 1.3E-21 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK95_RS02910 70a6019b736b52e4faf24ea34dfc4254 285 Pfam PF12849 PBP superfamily domain 32 260 6.8E-32 T 06-07-2017 IPR024370 PBP domain CAK95_RS02910 70a6019b736b52e4faf24ea34dfc4254 285 Gene3D G3DSA:3.40.190.10 44 125 4.4E-22 T 06-07-2017 CAK95_RS02910 70a6019b736b52e4faf24ea34dfc4254 285 Gene3D G3DSA:3.40.190.10 230 268 4.4E-22 T 06-07-2017 CAK95_RS02910 70a6019b736b52e4faf24ea34dfc4254 285 Gene3D G3DSA:3.40.190.10 126 229 1.3E-46 T 06-07-2017 CAK95_RS02910 70a6019b736b52e4faf24ea34dfc4254 285 SUPERFAMILY SSF53850 37 269 1.6E-38 T 06-07-2017 CAK95_RS00745 c8a6a22bc6f5026e1009915bc0b6fb17 332 Gene3D G3DSA:3.40.50.10490 1 175 6.5E-35 T 06-07-2017 CAK95_RS00745 c8a6a22bc6f5026e1009915bc0b6fb17 332 Gene3D G3DSA:3.40.50.10490 176 330 1.2E-30 T 06-07-2017 CAK95_RS00745 c8a6a22bc6f5026e1009915bc0b6fb17 332 Pfam PF01380 SIS domain 33 159 4.1E-19 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS00745 c8a6a22bc6f5026e1009915bc0b6fb17 332 Pfam PF01380 SIS domain 195 272 2.2E-11 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS00745 c8a6a22bc6f5026e1009915bc0b6fb17 332 SUPERFAMILY SSF53697 1 329 1.21E-64 T 06-07-2017 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 Pfam PF01687 Riboflavin kinase 193 314 1.6E-35 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 Gene3D G3DSA:2.40.30.30 189 317 6.5E-43 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 28 314 6.9E-77 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 SUPERFAMILY SSF82114 183 316 8.94E-45 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 Gene3D G3DSA:3.40.50.620 18 188 6.1E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 PIRSF PIRSF004491 13 320 1.7E-94 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 Pfam PF06574 FAD synthetase 22 174 5.9E-48 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 SMART SM00904 192 315 3.5E-55 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK95_RS13300 b2fc60aaee1767442d417df6ca7dce94 327 SUPERFAMILY SSF52374 26 184 1.16E-26 T 06-07-2017 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 Gene3D G3DSA:3.90.1150.10 295 387 1.2E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 Gene3D G3DSA:3.90.1150.10 3 48 1.2E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 386 44.91 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 385 2.3E-140 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 Gene3D G3DSA:3.40.640.10 49 290 2.4E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 Pfam PF00202 Aminotransferase class-III 13 384 2.5E-115 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS05855 f7909a2fb66b91e0802b2c8bf56281be 400 SUPERFAMILY SSF53383 5 386 1.02E-123 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS06790 3102f1dc11b3c4996dd8a2cac3d66ca4 225 Pfam PF00881 Nitroreductase family 35 203 2.5E-20 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK95_RS06790 3102f1dc11b3c4996dd8a2cac3d66ca4 225 Gene3D G3DSA:3.40.109.10 23 224 8.4E-42 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS06790 3102f1dc11b3c4996dd8a2cac3d66ca4 225 SUPERFAMILY SSF55469 22 224 1.83E-39 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 SMART SM00798 139 453 1.8E-199 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 528 6.3E-206 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 PIRSF PIRSF000414 2 528 1.3E-212 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 SUPERFAMILY SSF52335 8 198 1.44E-69 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 SUPERFAMILY SSF53927 214 528 9.33E-127 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Gene3D G3DSA:3.40.140.20 369 518 8.7E-57 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Gene3D G3DSA:3.40.50.1380 7 190 1.2E-82 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 452 4.3E-117 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 8 528 44.371 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 SMART SM00851 20 134 2.2E-56 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Pfam PF02142 MGS-like domain 20 133 1.6E-26 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK95_RS08490 7f6da41e681a73d7534d4160e812711c 528 Gene3D G3DSA:3.40.140.20 242 361 7.5E-48 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 SUPERFAMILY SSF51905 66 159 4.58E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 SUPERFAMILY SSF51905 340 429 4.58E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 SUPERFAMILY SSF51905 580 615 5.99E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 SUPERFAMILY SSF51905 71 337 5.99E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 SUPERFAMILY SSF51905 368 450 5.99E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 Pfam PF13450 NAD(P)-binding Rossmann-like domain 77 150 1.5E-12 T 06-07-2017 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 Pfam PF01593 Flavin containing amine oxidoreductase 519 615 2.7E-4 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 Gene3D G3DSA:3.50.50.60 352 492 2.8E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 Gene3D G3DSA:3.50.50.60 159 201 2.8E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS13125 bf4006bae572282abd30aaae5a221ea6 617 Gene3D G3DSA:3.50.50.60 71 123 2.8E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12480 c8669f14166a66335b64257621de74a9 159 SUPERFAMILY SSF143744 5 140 2.09E-35 T 06-07-2017 CAK95_RS12480 c8669f14166a66335b64257621de74a9 159 Pfam PF03928 Haem-degrading 7 137 4.2E-27 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS02705 1884d69ef4b4b3f21e50296a5b2f9e69 201 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 42 157 2.1E-13 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS02705 1884d69ef4b4b3f21e50296a5b2f9e69 201 SUPERFAMILY SSF52518 6 188 2.74E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02705 1884d69ef4b4b3f21e50296a5b2f9e69 201 Gene3D G3DSA:3.40.50.970 5 173 3.8E-20 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04425 7cdb453b7a3f53d1ad6e3f81f6dd9f13 300 SUPERFAMILY SSF88713 9 292 1.95E-58 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS04425 7cdb453b7a3f53d1ad6e3f81f6dd9f13 300 Pfam PF01522 Polysaccharide deacetylase 73 178 9.1E-6 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS04425 7cdb453b7a3f53d1ad6e3f81f6dd9f13 300 Gene3D G3DSA:3.20.20.370 9 292 5.9E-58 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 SUPERFAMILY SSF55681 10 238 2.81E-95 T 06-07-2017 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 SUPERFAMILY SSF55681 280 351 2.81E-95 T 06-07-2017 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Gene3D G3DSA:3.30.930.10 6 204 1.9E-94 T 06-07-2017 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Gene3D G3DSA:3.30.930.10 265 340 1.9E-94 T 06-07-2017 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 331 1.5E-36 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 5.0E-98 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.0E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.0E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.0E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.0E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 SUPERFAMILY SSF52954 337 440 6.38E-26 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Gene3D G3DSA:3.40.50.800 341 438 5.6E-23 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 440 62.323 T 06-07-2017 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CAK95_RS22925 b32aca2ca31a580e64f89f2eef717ca1 442 Pfam PF03129 Anticodon binding domain 348 437 4.6E-16 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.5E-39 T 06-07-2017 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 SMART SM00322 60 125 3.2E-9 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 Pfam PF07650 KH domain 39 111 8.7E-20 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 SUPERFAMILY SSF54814 2 106 3.92E-38 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.093 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 Gene3D G3DSA:3.30.1140.32 108 207 2.5E-47 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.8E-95 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 Gene3D G3DSA:3.30.300.20 17 107 8.5E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS21295 919dce5a2a1b102bfddd7446f42eb3cc 236 SUPERFAMILY SSF54821 108 206 2.75E-41 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS11605 1b8d9741efaea72c6b7ea8a606b512ab 178 Pfam PF04239 Protein of unknown function (DUF421) 105 170 1.8E-17 T 06-07-2017 IPR007353 Protein of unknown function DUF421 CAK95_RS11605 1b8d9741efaea72c6b7ea8a606b512ab 178 Gene3D G3DSA:3.30.240.20 96 166 2.5E-22 T 06-07-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CAK95_RS00920 4801fd5ab117e4917a90534c12cbb018 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 275 2.8E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 475 587 5.3E-39 T 06-07-2017 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 SUPERFAMILY SSF48019 271 397 2.81E-30 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Gene3D G3DSA:1.20.272.10 271 387 1.3E-25 T 06-07-2017 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 25 386 5.8E-122 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Gene3D G3DSA:3.40.50.300 37 194 5.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 SUPERFAMILY SSF52540 55 251 1.25E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Gene3D G3DSA:1.10.8.60 195 270 3.0E-32 T 06-07-2017 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 SMART SM00382 59 207 4.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Pfam PF13177 DNA polymerase III, delta subunit 42 205 2.7E-28 T 06-07-2017 CAK95_RS06595 d1e86c8e9d3a0114c5400f620c504143 616 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 260 401 2.5E-53 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 Pfam PF00355 Rieske [2Fe-2S] domain 108 161 1.7E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 10 37 6.4E-5 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 PRINTS PR00162 Rieske 2Fe-2S subunit signature 113 124 4.4E-16 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 PRINTS PR00162 Rieske 2Fe-2S subunit signature 147 159 4.4E-16 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 PRINTS PR00162 Rieske 2Fe-2S subunit signature 135 147 4.4E-16 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 Gene3D G3DSA:2.102.10.10 49 173 7.8E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 4 41 3.0E-20 T 06-07-2017 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 10 175 1.6E-70 T 06-07-2017 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 Gene3D G3DSA:1.20.5.510 5 41 9.0E-21 T 06-07-2017 CAK95_RS00565 a109457022b44c5e9d262957f0f5d49e 175 SUPERFAMILY SSF50022 31 170 4.0E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS24880 d9cc1251765ec49ae10d18274c8f0ce3 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 324 4.6E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS24880 d9cc1251765ec49ae10d18274c8f0ce3 329 SUPERFAMILY SSF53850 85 287 2.61E-11 T 06-07-2017 CAK95_RS24880 d9cc1251765ec49ae10d18274c8f0ce3 329 PIRSF PIRSF017082 1 326 2.2E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 SUPERFAMILY SSF46785 11 143 1.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 SUPERFAMILY SSF55729 153 297 7.98E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 SMART SM00347 29 129 4.5E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 Pfam PF12802 MarR family 36 93 2.5E-15 T 06-07-2017 CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 Gene3D G3DSA:3.40.630.30 154 306 1.2E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 Gene3D G3DSA:1.10.10.10 10 145 6.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11215 95bb64f766cf3bbc8af1f30aef6db911 318 Pfam PF13673 Acetyltransferase (GNAT) domain 202 290 1.5E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS22075 a1cf960cda56afebde48e80b9560f716 374 SUPERFAMILY SSF102405 89 292 1.5E-41 T 06-07-2017 CAK95_RS22075 a1cf960cda56afebde48e80b9560f716 374 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 77 289 5.1E-67 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAK95_RS22075 a1cf960cda56afebde48e80b9560f716 374 Pfam PF02481 DNA recombination-mediator protein A 80 283 4.3E-72 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAK95_RS22075 a1cf960cda56afebde48e80b9560f716 374 Gene3D G3DSA:3.40.50.450 118 262 1.9E-9 T 06-07-2017 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 157 224 4.6E-13 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 71 133 6.9E-11 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 Gene3D G3DSA:3.30.1150.10 140 225 6.4E-16 T 06-07-2017 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 Gene3D G3DSA:3.30.1150.10 22 133 6.8E-14 T 06-07-2017 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 71 133 7.5E-8 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 Pfam PF13103 TonB C terminal 164 210 1.8E-8 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 SUPERFAMILY SSF74653 26 133 7.06E-12 T 06-07-2017 CAK95_RS17340 7893cfddc3ee23535cdc0637f96ce76d 232 SUPERFAMILY SSF74653 139 225 6.41E-15 T 06-07-2017 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 292 1.5E-77 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 128 1.1E-34 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 SUPERFAMILY SSF46946 145 239 4.71E-25 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Pfam PF06827 Zinc finger found in FPG and IleRS 263 293 6.6E-10 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 293 42.205 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 SMART SM01232 145 243 7.5E-43 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Gene3D G3DSA:3.20.190.10 2 145 1.7E-38 T 06-07-2017 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Gene3D G3DSA:1.10.8.50 146 293 1.2E-44 T 06-07-2017 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 145 240 3.1E-19 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 SMART SM00898 2 129 5.0E-53 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 SUPERFAMILY SSF81624 2 154 3.01E-38 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 SUPERFAMILY SSF57716 239 293 4.28E-15 T 06-07-2017 CAK95_RS11060 1a02bfbf73d238fc3a061745375ee260 293 ProSitePatterns PS01242 Zinc finger FPG-type signature. 266 292 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAK95_RS17530 b43189fe17fc67013ca54fba67d3337a 437 Pfam PF13657 HipA N-terminal domain 10 109 4.0E-25 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAK95_RS17530 b43189fe17fc67013ca54fba67d3337a 437 Pfam PF07804 HipA-like C-terminal domain 252 403 3.1E-31 T 06-07-2017 IPR012893 HipA-like, C-terminal CAK95_RS17530 b43189fe17fc67013ca54fba67d3337a 437 Pfam PF07805 HipA-like N-terminal domain 157 242 5.4E-19 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAK95_RS17530 b43189fe17fc67013ca54fba67d3337a 437 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 10 109 2.8E-29 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01182 Ornithine decarboxylase signature 86 110 2.3E-21 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01182 Ornithine decarboxylase signature 16 40 2.3E-21 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01182 Ornithine decarboxylase signature 116 138 2.3E-21 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01182 Ornithine decarboxylase signature 318 328 2.3E-21 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01182 Ornithine decarboxylase signature 42 69 2.3E-21 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 31 259 2.5E-55 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 Gene3D G3DSA:3.20.20.10 25 244 8.4E-67 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 SUPERFAMILY SSF51419 22 261 1.89E-66 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 266 374 3.6E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 44 62 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 Gene3D G3DSA:2.40.37.10 245 374 2.9E-27 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 SUPERFAMILY SSF50621 231 376 6.07E-34 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 62 4.8E-18 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 166 179 4.8E-18 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 76 4.8E-18 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12935 410210807d7bebe1b6a0e3e337d71504 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 249 268 4.8E-18 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 Pfam PF00120 Glutamine synthetase, catalytic domain 103 331 2.5E-15 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 Gene3D G3DSA:3.30.590.10 103 332 2.0E-57 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 SUPERFAMILY SSF55931 101 332 9.32E-58 T 06-07-2017 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 84 2.4E-14 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 SUPERFAMILY SSF54368 32 86 1.96E-7 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 217 234 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 SMART SM01230 89 333 1.6E-46 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS26405 9df1f4fd31cf57aca4781a2d87f90c01 345 ProSitePatterns PS00180 Glutamine synthetase signature 1. 43 60 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK95_RS17805 6894ec66e2f4d4d223e56217d2f07d10 250 Gene3D G3DSA:1.20.120.10 128 249 1.8E-33 T 06-07-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 CAK95_RS17805 6894ec66e2f4d4d223e56217d2f07d10 250 SUPERFAMILY SSF47175 128 248 2.06E-30 T 06-07-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 CAK95_RS17805 6894ec66e2f4d4d223e56217d2f07d10 250 Pfam PF01322 Cytochrome C' 130 247 1.5E-27 T 06-07-2017 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Pfam PF00501 AMP-binding enzyme 8 407 6.4E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Gene3D G3DSA:3.30.300.30 404 500 1.0E-33 T 06-07-2017 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Gene3D G3DSA:3.40.50.980 3 167 1.8E-39 T 06-07-2017 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 4.4E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Gene3D G3DSA:3.40.50.980 168 319 9.4E-39 T 06-07-2017 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 Gene3D G3DSA:2.30.38.10 328 401 4.7E-26 T 06-07-2017 CAK95_RS27070 76e3aa87bbfe990d7e582e8c2d38c3f4 503 SUPERFAMILY SSF56801 3 500 3.79E-155 T 06-07-2017 CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 Gene3D G3DSA:1.10.10.10 148 217 5.6E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 SMART SM00419 167 216 6.6E-4 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 Pfam PF13545 Crp-like helix-turn-helix domain 151 221 1.4E-9 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 SUPERFAMILY SSF46785 148 222 1.46E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 7.4E-18 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 SUPERFAMILY SSF51206 6 140 2.49E-27 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 Gene3D G3DSA:2.60.120.10 15 138 1.7E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS12995 c44813ea89e14660e5ccbf84f61f4632 225 SMART SM00100 13 131 2.5E-7 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 103 127 - T 06-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 Pfam PF00854 POT family 243 426 1.6E-27 T 06-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 Pfam PF00854 POT family 115 223 1.4E-28 T 06-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 228 2.4E-56 T 06-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 SUPERFAMILY SSF103473 19 453 1.44E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 174 186 - T 06-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 Gene3D G3DSA:1.20.1250.20 301 450 1.4E-5 T 06-07-2017 CAK95_RS22800 766fc3b2f70124796d3117000228b988 458 Gene3D G3DSA:1.20.1250.20 27 232 9.6E-20 T 06-07-2017 CAK95_RS20930 c3fec253cfb3ec2f9d4ee9db7fa2e221 326 SUPERFAMILY SSF56281 29 321 2.75E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20930 c3fec253cfb3ec2f9d4ee9db7fa2e221 326 Pfam PF00753 Metallo-beta-lactamase superfamily 95 291 7.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20930 c3fec253cfb3ec2f9d4ee9db7fa2e221 326 SMART SM00849 91 299 4.3E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20930 c3fec253cfb3ec2f9d4ee9db7fa2e221 326 Gene3D G3DSA:3.60.15.10 33 318 1.2E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20165 c825ab80c915a190a4ac373c6d39e7d8 395 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 211 1.6E-14 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK95_RS20165 c825ab80c915a190a4ac373c6d39e7d8 395 Gene3D G3DSA:3.40.47.10 4 262 1.1E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS20165 c825ab80c915a190a4ac373c6d39e7d8 395 SUPERFAMILY SSF53901 226 382 3.55E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS20165 c825ab80c915a190a4ac373c6d39e7d8 395 SUPERFAMILY SSF53901 6 256 1.94E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 SUPERFAMILY SSF54373 177 272 2.55E-5 T 06-07-2017 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 SUPERFAMILY SSF51905 6 172 1.5E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 SUPERFAMILY SSF51905 271 365 1.5E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 Pfam PF01494 FAD binding domain 6 342 2.9E-19 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.2E-18 T 06-07-2017 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.2E-18 T 06-07-2017 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.2E-18 T 06-07-2017 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.2E-18 T 06-07-2017 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 Gene3D G3DSA:3.50.50.60 272 351 3.4E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS28770 62d8c5973c27aedb8dcebf867ae69d51 376 Gene3D G3DSA:3.50.50.60 5 177 3.4E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11250 268ce5f24830a357f66b352a47e2b270 116 Pfam PF01042 Endoribonuclease L-PSP 13 115 1.1E-23 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS11250 268ce5f24830a357f66b352a47e2b270 116 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 06-07-2017 IPR019897 RidA, conserved site CAK95_RS11250 268ce5f24830a357f66b352a47e2b270 116 Gene3D G3DSA:3.30.1330.40 11 116 2.7E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS11250 268ce5f24830a357f66b352a47e2b270 116 SUPERFAMILY SSF55298 6 115 1.88E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS11525 7783930c639ff73d70c791519da29515 400 Pfam PF13458 Periplasmic binding protein 13 347 1.4E-60 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS11525 7783930c639ff73d70c791519da29515 400 SUPERFAMILY SSF53822 13 365 1.96E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS11525 7783930c639ff73d70c791519da29515 400 Gene3D G3DSA:3.40.50.2300 12 214 9.0E-43 T 06-07-2017 CAK95_RS17435 1caa3bedf434a8e8be37343e6f160c1b 233 Gene3D G3DSA:3.40.50.300 1 230 1.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17435 1caa3bedf434a8e8be37343e6f160c1b 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17435 1caa3bedf434a8e8be37343e6f160c1b 233 Pfam PF00005 ABC transporter 17 161 7.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17435 1caa3bedf434a8e8be37343e6f160c1b 233 SMART SM00382 26 212 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17435 1caa3bedf434a8e8be37343e6f160c1b 233 SUPERFAMILY SSF52540 2 227 2.77E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 Pfam PF12728 Helix-turn-helix domain 4 52 5.6E-14 T 06-07-2017 CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 51 5.4E-11 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 Gene3D G3DSA:1.10.10.10 4 52 6.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 Pfam PF12727 PBP superfamily domain 82 268 4.9E-39 T 06-07-2017 IPR024370 PBP domain CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 Gene3D G3DSA:3.40.190.10 147 246 9.5E-5 T 06-07-2017 CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 SUPERFAMILY SSF53850 139 243 6.07E-6 T 06-07-2017 CAK95_RS02925 84656a53a6ef1bfecbba35f7f0115ef4 295 SUPERFAMILY SSF46955 4 52 5.86E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS20800 663a7ab41271212ee37df77dac3263d1 435 Gene3D G3DSA:3.90.226.10 70 171 1.6E-7 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS20800 663a7ab41271212ee37df77dac3263d1 435 SUPERFAMILY SSF52096 51 194 2.58E-10 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 20 42 - T 06-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 PIRSF PIRSF000194 4 175 1.5E-61 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 PRINTS PR00070 Dihydrofolate reductase signature 104 118 6.5E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 PRINTS PR00070 Dihydrofolate reductase signature 20 30 6.5E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 PRINTS PR00070 Dihydrofolate reductase signature 47 58 6.5E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 PRINTS PR00070 Dihydrofolate reductase signature 34 42 6.5E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 Gene3D G3DSA:3.40.430.10 5 173 5.4E-60 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 Pfam PF00186 Dihydrofolate reductase 9 172 1.1E-56 T 06-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK95_RS14610 42704119f93470669196a84e1dd4cce5 181 SUPERFAMILY SSF53597 8 173 1.68E-56 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PIRSF PIRSF002764 1 222 1.7E-69 T 06-07-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 Pfam PF03379 CcmB protein 6 218 9.1E-83 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 102 120 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 1.3E-62 T 06-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07570 d1bae1b99b61f9988b6335d150c63f0c 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 7 218 6.5E-83 T 06-07-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 SMART SM00283 486 733 7.7E-90 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 Gene3D G3DSA:1.10.287.950 500 705 5.2E-60 T 06-07-2017 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 551 729 4.3E-56 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 Pfam PF00672 HAMP domain 332 395 1.9E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 SUPERFAMILY SSF158472 351 395 1.57E-8 T 06-07-2017 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 SUPERFAMILY SSF58104 453 734 2.22E-71 T 06-07-2017 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 SMART SM00304 433 485 0.0073 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS09300 e959b8177f71edfb194b5b6dae11f589 793 SMART SM00304 351 404 3.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 392 6.7E-53 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 6.7E-53 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 257 286 6.7E-53 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 334 361 6.7E-53 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 SUPERFAMILY SSF58104 203 484 2.75E-71 T 06-07-2017 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 295 482 2.0E-59 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 Gene3D G3DSA:1.10.287.950 251 455 1.7E-60 T 06-07-2017 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 Pfam PF11563 Protoglobin 4 168 5.2E-38 T 06-07-2017 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 SMART SM00283 236 483 3.5E-94 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 Gene3D G3DSA:1.10.490.10 2 160 8.4E-40 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK95_RS25170 25074a141a582f6cfb099872f973226f 516 SUPERFAMILY SSF46458 4 160 1.18E-30 T 06-07-2017 IPR009050 Globin-like CAK95_RS25545 f6948553ad36a811933eb89a7e992ab8 217 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 210 3.2E-40 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS25545 f6948553ad36a811933eb89a7e992ab8 217 Pfam PF01914 MarC family integral membrane protein 6 213 2.0E-43 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS19520 b3c9355fcb1d300efbdb279ff473c3af 181 Gene3D G3DSA:2.10.109.10 34 90 1.3E-11 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS19520 b3c9355fcb1d300efbdb279ff473c3af 181 Gene3D G3DSA:2.10.109.10 128 174 1.3E-11 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS19520 b3c9355fcb1d300efbdb279ff473c3af 181 Pfam PF10502 Signal peptidase, peptidase S26 29 166 8.5E-52 T 06-07-2017 IPR019533 Peptidase S26 CAK95_RS19520 b3c9355fcb1d300efbdb279ff473c3af 181 SUPERFAMILY SSF51306 31 179 2.82E-25 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS28035 9c8f118eec00d414781ac0358676ea40 393 Gene3D G3DSA:3.30.2010.10 166 249 2.2E-17 T 06-07-2017 CAK95_RS28035 9c8f118eec00d414781ac0358676ea40 393 Pfam PF01435 Peptidase family M48 173 340 9.4E-26 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS06175 a520c41a2f23052b81a6faeb67bb587e 286 SUPERFAMILY SSF100950 2 273 7.18E-74 T 06-07-2017 CAK95_RS06175 a520c41a2f23052b81a6faeb67bb587e 286 SMART SM00882 4 225 9.0E-34 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK95_RS06175 a520c41a2f23052b81a6faeb67bb587e 286 Gene3D G3DSA:3.40.1080.10 2 120 5.6E-75 T 06-07-2017 CAK95_RS06175 a520c41a2f23052b81a6faeb67bb587e 286 Gene3D G3DSA:3.40.1080.10 158 282 5.6E-75 T 06-07-2017 CAK95_RS06175 a520c41a2f23052b81a6faeb67bb587e 286 Pfam PF01144 Coenzyme A transferase 4 218 6.5E-22 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 TIGRFAM TIGR01351 adk: adenylate kinase 2 132 3.5E-52 T 06-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 SUPERFAMILY SSF52540 1 192 2.54E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 Pfam PF00406 Adenylate kinase 5 169 2.2E-56 T 06-07-2017 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 Gene3D G3DSA:3.40.50.300 1 190 3.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 Hamap MF_00235 Adenylate kinase [adk]. 1 192 44.048 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 PRINTS PR00094 Adenylate kinase signature 81 97 5.3E-34 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 PRINTS PR00094 Adenylate kinase signature 139 154 5.3E-34 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 PRINTS PR00094 Adenylate kinase signature 4 17 5.3E-34 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 PRINTS PR00094 Adenylate kinase signature 32 46 5.3E-34 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS21370 9eeae282d0bc5c5c173cb5cc4aec660d 312 PRINTS PR00094 Adenylate kinase signature 156 170 5.3E-34 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK95_RS15545 49d8418efc9caf13b459a72e64dbf18a 492 SUPERFAMILY SSF53720 11 491 1.11E-135 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS15545 49d8418efc9caf13b459a72e64dbf18a 492 Pfam PF00171 Aldehyde dehydrogenase family 14 486 5.8E-141 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS15545 49d8418efc9caf13b459a72e64dbf18a 492 Gene3D G3DSA:3.40.605.10 8 281 9.1E-74 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS15545 49d8418efc9caf13b459a72e64dbf18a 492 Gene3D G3DSA:3.40.309.10 282 463 5.6E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 Pfam PF08281 Sigma-70, region 4 120 172 2.4E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 Gene3D G3DSA:1.10.1740.10 2 106 5.0E-27 T 06-07-2017 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 Pfam PF04542 Sigma-70 region 2 25 90 1.9E-19 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 SUPERFAMILY SSF88659 112 176 2.99E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 175 5.2E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 Gene3D G3DSA:1.10.10.10 113 178 1.5E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11855 6c318904c8030842a92a8f787a97d097 187 SUPERFAMILY SSF88946 1 103 9.89E-27 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS14495 f155c025c29abee49d023cbd04138214 362 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 40 362 9.9E-124 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK95_RS14495 f155c025c29abee49d023cbd04138214 362 ProSitePatterns PS01347 MraY family signature 1. 69 81 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK95_RS14495 f155c025c29abee49d023cbd04138214 362 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 24 360 24.267 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK95_RS14495 f155c025c29abee49d023cbd04138214 362 ProSitePatterns PS01348 MraY family signature 2. 191 202 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK95_RS14495 f155c025c29abee49d023cbd04138214 362 Pfam PF00953 Glycosyl transferase family 4 100 285 4.2E-34 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAK95_RS26455 9ab7c243814958391356106facca0964 262 SUPERFAMILY SSF53681 8 109 4.9E-29 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 73 81 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 221 2.4E-24 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 186 196 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 Hamap MF_00258 Glutamate racemase [murI]. 6 259 29.401 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 229 1.7E-53 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 SUPERFAMILY SSF53681 112 246 6.93E-27 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS26455 9ab7c243814958391356106facca0964 262 Gene3D G3DSA:3.40.50.1860 6 174 1.5E-42 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 Gene3D G3DSA:3.30.70.600 4 102 1.3E-46 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 7.2E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 7.2E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 7.2E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 SMART SM01403 7 101 7.3E-61 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 5.8E-38 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.006 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 SUPERFAMILY SSF54999 6 102 8.76E-41 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK95_RS21260 6b003258d58cad5e6395bc36ff30e6ed 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.4E-48 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS03765 f417938fe127e83446b3e4f1f64ea50e 454 Gene3D G3DSA:3.40.190.10 129 250 2.7E-14 T 06-07-2017 CAK95_RS03765 f417938fe127e83446b3e4f1f64ea50e 454 SUPERFAMILY SSF160387 389 449 8.89E-8 T 06-07-2017 CAK95_RS03765 f417938fe127e83446b3e4f1f64ea50e 454 SUPERFAMILY SSF53850 28 319 4.6E-37 T 06-07-2017 CAK95_RS03765 f417938fe127e83446b3e4f1f64ea50e 454 Pfam PF09084 NMT1/THI5 like 126 265 2.1E-12 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Gene3D G3DSA:1.10.540.10 1 118 3.0E-42 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 3.9E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Gene3D G3DSA:2.40.110.10 121 216 3.2E-39 T 06-07-2017 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 SUPERFAMILY SSF47203 226 378 2.26E-57 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 5.6E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 4.4E-50 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 Gene3D G3DSA:1.20.140.10 217 378 2.9E-66 T 06-07-2017 CAK95_RS22400 5b8b4a645b2c2634436aa84b2841a92c 379 SUPERFAMILY SSF56645 1 240 2.49E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.30.70.20 228 258 8.1E-4 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 94 3.3E-23 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SMART SM00926 248 302 9.1E-15 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.40.228.10 381 568 5.7E-59 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 140 3.2E-17 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 249 300 2.4E-14 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.10.20.30 14 74 9.6E-8 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SUPERFAMILY SSF54292 19 92 1.57E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 178 189 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Pfam PF01568 Molydopterin dinucleotide binding domain 820 924 7.7E-28 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.40.50.740 305 379 1.9E-83 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.40.50.740 624 773 1.9E-83 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.40.50.740 569 591 1.9E-83 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SUPERFAMILY SSF54862 93 243 3.98E-37 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SUPERFAMILY SSF50692 786 929 7.46E-41 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 221 232 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:3.30.70.20 164 227 3.6E-14 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 253 928 9.8E-288 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SMART SM00929 101 141 7.6E-20 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:2.40.40.20 774 930 1.9E-41 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 PIRSF PIRSF036643 15 958 0.0 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Pfam PF00384 Molybdopterin oxidoreductase 305 736 5.9E-75 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 SUPERFAMILY SSF53706 248 773 8.77E-189 T 06-07-2017 CAK95_RS12300 8fc168397a3637f24805d393b5c01654 958 Gene3D G3DSA:2.20.25.90 259 302 8.0E-18 T 06-07-2017 CAK95_RS25465 09388c8a32836d3b2903afa692ed08d6 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 242 1.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS25465 09388c8a32836d3b2903afa692ed08d6 260 SUPERFAMILY SSF161098 58 236 1.57E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS25465 09388c8a32836d3b2903afa692ed08d6 260 Gene3D G3DSA:1.10.3720.10 57 246 4.4E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 Gene3D G3DSA:2.30.40.10 478 538 8.4E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 SUPERFAMILY SSF51338 3 66 2.65E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 SUPERFAMILY SSF51338 497 546 2.65E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 Pfam PF07969 Amidohydrolase family 54 538 3.8E-114 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 SUPERFAMILY SSF51556 65 127 1.17E-42 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 SUPERFAMILY SSF51556 207 497 1.17E-42 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 Gene3D G3DSA:3.20.20.140 211 477 4.0E-18 T 06-07-2017 CAK95_RS03395 42040d98528676aedb700b3c0f337a84 629 Gene3D G3DSA:2.30.40.10 8 86 6.2E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 36 434 1.9E-77 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 Gene3D G3DSA:1.20.1250.20 292 475 1.1E-18 T 06-07-2017 CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 Gene3D G3DSA:1.20.1250.20 31 212 6.0E-34 T 06-07-2017 CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 Pfam PF07690 Major Facilitator Superfamily 39 432 5.0E-55 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 SUPERFAMILY SSF103473 270 476 3.79E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS18930 e943699a633ddb415300832f2fd6c8fb 489 SUPERFAMILY SSF103473 23 215 3.79E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS05105 e622e8b805ae0e969ce259ed7173aea1 126 SUPERFAMILY SSF46689 59 111 1.08E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05105 e622e8b805ae0e969ce259ed7173aea1 126 Gene3D G3DSA:1.10.10.60 58 112 1.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05105 e622e8b805ae0e969ce259ed7173aea1 126 SMART SM00342 24 106 2.1E-14 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS05105 e622e8b805ae0e969ce259ed7173aea1 126 Pfam PF12833 Helix-turn-helix domain 31 108 3.1E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS04115 d13ab2404f8c2c290b0cf529b315db21 202 SUPERFAMILY SSF100950 18 200 1.27E-39 T 06-07-2017 CAK95_RS04115 d13ab2404f8c2c290b0cf529b315db21 202 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 18 194 1.0E-39 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK95_RS04115 d13ab2404f8c2c290b0cf529b315db21 202 Gene3D G3DSA:3.40.50.10420 18 200 2.9E-42 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAK95_RS04115 d13ab2404f8c2c290b0cf529b315db21 202 PIRSF PIRSF006806 14 197 5.7E-29 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK95_RS04115 d13ab2404f8c2c290b0cf529b315db21 202 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 18 194 2.6E-30 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK95_RS07985 6093ca27a1bb72a0b434fc4a2565a9f1 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 47.472 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAK95_RS07985 6093ca27a1bb72a0b434fc4a2565a9f1 259 Gene3D G3DSA:3.20.20.70 6 257 1.4E-108 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS07985 6093ca27a1bb72a0b434fc4a2565a9f1 259 Pfam PF00977 Histidine biosynthesis protein 6 240 7.8E-91 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAK95_RS07985 6093ca27a1bb72a0b434fc4a2565a9f1 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 5 256 1.4E-108 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAK95_RS07985 6093ca27a1bb72a0b434fc4a2565a9f1 259 SUPERFAMILY SSF51366 4 256 9.42E-84 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS28765 404731622e40be8234a016ffae28ada0 311 Gene3D G3DSA:3.40.190.10 101 223 7.7E-4 T 06-07-2017 CAK95_RS28765 404731622e40be8234a016ffae28ada0 311 Pfam PF09084 NMT1/THI5 like 14 227 5.4E-10 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS28765 404731622e40be8234a016ffae28ada0 311 SUPERFAMILY SSF53850 14 282 2.51E-15 T 06-07-2017 CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Gene3D G3DSA:2.60.40.420 28 159 8.2E-20 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Gene3D G3DSA:2.60.40.420 372 487 7.8E-38 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Gene3D G3DSA:2.60.40.420 160 346 4.3E-26 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Pfam PF00394 Multicopper oxidase 218 329 8.9E-11 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 SUPERFAMILY SSF49503 161 337 1.94E-20 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Pfam PF07732 Multicopper oxidase 70 154 7.9E-20 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 ProSitePatterns PS00079 Multicopper oxidases signature 1. 465 485 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 Pfam PF07731 Multicopper oxidase 381 485 5.9E-29 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 SUPERFAMILY SSF49503 43 158 3.76E-23 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 ProSitePatterns PS00080 Multicopper oxidases signature 2. 470 481 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS02380 891e7b99fae2ba054973c281f4bf3ce6 489 SUPERFAMILY SSF49503 350 485 1.3E-35 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS28730 c47b323272da6594a8f5bb24186327b2 360 Pfam PF00795 Carbon-nitrogen hydrolase 8 292 6.0E-37 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS28730 c47b323272da6594a8f5bb24186327b2 360 SUPERFAMILY SSF56317 6 314 3.4E-55 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS28730 c47b323272da6594a8f5bb24186327b2 360 Gene3D G3DSA:3.60.110.10 6 313 7.7E-54 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 SUPERFAMILY SSF52540 3 246 8.74E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 3.0E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 SMART SM00382 30 226 1.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 Pfam PF00005 ABC transporter 22 177 1.2E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 Gene3D G3DSA:3.40.50.300 3 244 7.8E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09895 9fd15c3a822d8a560a9e964bff7181f8 250 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05145 0bee73236b79a9f646ddf2708ba0a2a0 304 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 3 287 19.875 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK95_RS05145 0bee73236b79a9f646ddf2708ba0a2a0 304 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 57 79 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site CAK95_RS05145 0bee73236b79a9f646ddf2708ba0a2a0 304 Pfam PF01040 UbiA prenyltransferase family 19 267 1.3E-55 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK95_RS05145 0bee73236b79a9f646ddf2708ba0a2a0 304 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 6 285 4.2E-96 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 SUPERFAMILY SSF53067 12 131 3.89E-33 T 06-07-2017 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 Gene3D G3DSA:3.30.420.150 138 305 8.2E-26 T 06-07-2017 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 12 302 7.6E-94 T 06-07-2017 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 Gene3D G3DSA:3.30.420.40 10 131 5.6E-36 T 06-07-2017 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 Pfam PF02541 Ppx/GppA phosphatase family 31 303 2.5E-42 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 SUPERFAMILY SSF109604 326 472 8.16E-15 T 06-07-2017 CAK95_RS25720 d53231170ec1f2929cda9d12cd9ca6ed 500 SUPERFAMILY SSF53067 135 304 9.58E-34 T 06-07-2017 CAK95_RS27725 b3deec9202c4532988a2dabf21807275 312 Pfam PF13030 Protein of unknown function (DUF3891) 48 282 5.7E-31 T 06-07-2017 IPR024992 Protein of unknown function DUF3891 CAK95_RS12140 38d114188209b813e10cd8b8b2c45bc4 375 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 40 372 1.7E-76 T 06-07-2017 IPR018666 Protein of unknown function DUF2125 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Gene3D G3DSA:3.30.300.30 515 630 3.8E-26 T 06-07-2017 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Gene3D G3DSA:3.40.50.980 78 263 2.2E-44 T 06-07-2017 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 1 642 52.882 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 640 0.0 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Pfam PF00501 AMP-binding enzyme 82 519 3.3E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 7.4E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 23 80 5.2E-24 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Gene3D G3DSA:3.40.50.980 264 421 1.7E-25 T 06-07-2017 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 Gene3D G3DSA:2.30.38.10 436 512 3.7E-8 T 06-07-2017 CAK95_RS08465 f29d5387e7cb1a897fc910dcc90fed35 646 SUPERFAMILY SSF56801 11 639 2.62E-184 T 06-07-2017 CAK95_RS23640 311d07633f3642320ed4bcd5c71b7436 121 Pfam PF05656 Protein of unknown function (DUF805) 14 118 1.1E-31 T 06-07-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 21 235 2.4E-28 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 SUPERFAMILY SSF51621 7 249 1.39E-52 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 Gene3D G3DSA:3.50.30.50 307 549 1.5E-55 T 06-07-2017 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 Pfam PF04199 Putative cyclase 311 487 7.7E-32 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 SUPERFAMILY SSF102198 308 548 6.54E-48 T 06-07-2017 CAK95_RS27375 bbbc7b6a967cc9357ed42340c0e8fd06 550 Gene3D G3DSA:3.20.20.60 8 251 9.8E-52 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 65 5.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 Gene3D G3DSA:1.10.10.10 2 83 2.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 SUPERFAMILY SSF46785 3 114 1.87E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 SUPERFAMILY SSF53850 92 298 2.05E-42 T 06-07-2017 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 Gene3D G3DSA:3.40.190.10 179 268 1.3E-33 T 06-07-2017 CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 Pfam PF03466 LysR substrate binding domain 91 296 3.7E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS16905 f56d165d51ff832bf0920ad77bbbfcec 318 Gene3D G3DSA:3.40.190.10 93 178 4.7E-23 T 06-07-2017 CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 Pfam PF11967 Recombination protein O N terminal 1 70 9.8E-16 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 SUPERFAMILY SSF57863 89 185 9.15E-10 T 06-07-2017 CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 Hamap MF_00201 DNA repair protein RecO [recO]. 1 237 17.49 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 132 237 1.0E-31 T 06-07-2017 CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 SUPERFAMILY SSF50249 1 67 4.45E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 Pfam PF02565 Recombination protein O C terminal 83 221 1.7E-24 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK95_RS22365 cf0c12521ca1ad8fb17e6347d792f43e 245 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 235 1.9E-34 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 Pfam PF01026 TatD related DNase 3 254 1.2E-77 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 PIRSF PIRSF005902 1 257 3.5E-79 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 1.4E-80 T 06-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 SUPERFAMILY SSF51556 1 254 3.6E-87 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS23305 c689645a207d4e57ad1318630efa8755 264 Gene3D G3DSA:3.20.20.140 1 254 6.2E-87 T 06-07-2017 CAK95_RS06670 57b25dc2b49dcd409e668e5a8d86bb2e 473 Gene3D G3DSA:3.40.50.300 211 427 6.9E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06670 57b25dc2b49dcd409e668e5a8d86bb2e 473 Gene3D G3DSA:3.30.450.90 110 207 4.2E-36 T 06-07-2017 CAK95_RS06670 57b25dc2b49dcd409e668e5a8d86bb2e 473 Pfam PF00437 Type II/IV secretion system protein 114 389 2.6E-82 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAK95_RS06670 57b25dc2b49dcd409e668e5a8d86bb2e 473 SUPERFAMILY SSF52540 94 403 8.25E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12620 da12569932034434863aa96bfffcb56c 360 SUPERFAMILY SSF51556 17 342 1.72E-60 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS12620 da12569932034434863aa96bfffcb56c 360 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 19 344 2.3E-77 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CAK95_RS12620 da12569932034434863aa96bfffcb56c 360 Gene3D G3DSA:3.20.20.140 15 346 8.6E-73 T 06-07-2017 CAK95_RS12620 da12569932034434863aa96bfffcb56c 360 Pfam PF00962 Adenosine/AMP deaminase 19 343 2.1E-45 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 SUPERFAMILY SSF48371 979 1024 1.09E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 SUPERFAMILY SSF48371 1107 1151 1.09E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 SUPERFAMILY SSF48371 786 918 1.09E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 Gene3D G3DSA:1.25.10.10 1111 1183 5.8E-5 T 06-07-2017 IPR011989 Armadillo-like helical CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 Gene3D G3DSA:1.25.10.10 788 912 5.8E-5 T 06-07-2017 IPR011989 Armadillo-like helical CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 Pfam PF05729 NACHT domain 338 501 1.4E-8 T 06-07-2017 CAK95_RS03370 a9f988e218d371d30c2d1a1d912927aa 1661 SUPERFAMILY SSF52540 339 472 2.23E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13280 5e475a14dff87d1ce936f35f3c9dc233 567 SUPERFAMILY SSF141868 288 524 1.44E-39 T 06-07-2017 IPR001633 EAL domain CAK95_RS13280 5e475a14dff87d1ce936f35f3c9dc233 567 Pfam PF00563 EAL domain 288 520 3.7E-44 T 06-07-2017 IPR001633 EAL domain CAK95_RS13280 5e475a14dff87d1ce936f35f3c9dc233 567 SMART SM00052 281 525 3.2E-11 T 06-07-2017 IPR001633 EAL domain CAK95_RS13280 5e475a14dff87d1ce936f35f3c9dc233 567 Gene3D G3DSA:3.20.20.450 285 524 6.7E-35 T 06-07-2017 IPR001633 EAL domain CAK95_RS28570 c398240be4d72fc4db4ab054e1fff0bb 163 SUPERFAMILY SSF50494 16 48 7.45E-11 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS28570 c398240be4d72fc4db4ab054e1fff0bb 163 Gene3D G3DSA:2.40.10.10 14 48 7.8E-12 T 06-07-2017 CAK95_RS12200 ab6685c1b8b5688224d8106a8549dbe2 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 2.0E-13 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS12200 ab6685c1b8b5688224d8106a8549dbe2 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 4.7E-23 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS12200 ab6685c1b8b5688224d8106a8549dbe2 44 Pfam PF00468 Ribosomal protein L34 2 44 3.1E-23 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS12200 ab6685c1b8b5688224d8106a8549dbe2 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS12200 ab6685c1b8b5688224d8106a8549dbe2 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.574 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 SUPERFAMILY SSF54534 1547 1615 9.29E-6 T 06-07-2017 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Pfam PF13245 Part of AAA domain 424 480 8.3E-11 T 06-07-2017 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 SUPERFAMILY SSF52980 1402 1508 3.93E-12 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Pfam PF13087 AAA domain 1187 1364 1.3E-15 T 06-07-2017 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 1548 1615 5.1E-7 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Pfam PF04480 Protein of unknown function (DUF559) 1413 1499 2.6E-4 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 SUPERFAMILY SSF52540 1099 1379 3.06E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 SUPERFAMILY SSF52540 414 546 3.06E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Gene3D G3DSA:3.40.50.300 1205 1367 1.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Gene3D G3DSA:3.10.50.30 1547 1616 6.5E-8 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Gene3D G3DSA:3.40.50.300 403 529 2.7E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11715 174d0f5174640882822f1dd8f375ea2d 1624 Gene3D G3DSA:3.40.50.300 1108 1204 2.7E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23570 04e67c3614c2c35daab0895c3ee3edc3 370 SUPERFAMILY SSF89796 2 360 6.93E-105 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS23570 04e67c3614c2c35daab0895c3ee3edc3 370 Gene3D G3DSA:3.40.50.10540 297 345 1.9E-86 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS23570 04e67c3614c2c35daab0895c3ee3edc3 370 Gene3D G3DSA:3.40.50.10540 3 215 1.9E-86 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS23570 04e67c3614c2c35daab0895c3ee3edc3 370 Pfam PF02515 CoA-transferase family III 5 347 1.2E-91 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS23570 04e67c3614c2c35daab0895c3ee3edc3 370 Gene3D G3DSA:3.30.1540.10 231 296 6.0E-9 T 06-07-2017 CAK95_RS27795 08523aac7d73a191d72432051fef7ad3 185 Gene3D G3DSA:3.20.20.140 15 184 2.1E-43 T 06-07-2017 CAK95_RS27795 08523aac7d73a191d72432051fef7ad3 185 Pfam PF04909 Amidohydrolase 15 184 3.1E-20 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS27795 08523aac7d73a191d72432051fef7ad3 185 SUPERFAMILY SSF51556 16 185 7.56E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SUPERFAMILY SSF55785 33 142 3.14E-24 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Gene3D G3DSA:3.30.565.10 351 506 3.5E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00388 285 351 3.7E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SUPERFAMILY SSF47384 274 348 2.75E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00086 94 135 27.0 T 06-07-2017 IPR001610 PAC motif CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00086 221 263 0.02 T 06-07-2017 IPR001610 PAC motif CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Gene3D G3DSA:3.30.450.20 18 132 6.1E-23 T 06-07-2017 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Pfam PF00512 His Kinase A (phospho-acceptor) domain 285 349 3.2E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SUPERFAMILY SSF52172 528 641 4.13E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Pfam PF13426 PAS domain 33 134 5.2E-12 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Pfam PF13426 PAS domain 162 262 4.3E-12 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Gene3D G3DSA:3.30.450.20 133 261 1.5E-27 T 06-07-2017 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SUPERFAMILY SSF55785 131 258 2.42E-27 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Gene3D G3DSA:3.40.50.2300 527 642 1.6E-28 T 06-07-2017 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00387 392 508 3.8E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Pfam PF00072 Response regulator receiver domain 529 612 3.9E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 142 1.8E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 270 2.0E-18 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00448 527 635 2.3E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 507 9.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 3.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 451 3.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 3.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 465 3.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 Gene3D G3DSA:1.10.287.130 280 347 0.001 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00091 147 214 4.7E-4 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SMART SM00091 20 89 2.2E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS26315 821963dbb5dcb484cedf810999325439 645 SUPERFAMILY SSF55874 341 507 2.88E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 SUPERFAMILY SSF56784 4 161 2.38E-42 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 Pfam PF13242 HAD-hyrolase-like 110 159 6.3E-7 T 06-07-2017 CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 8 153 9.7E-37 T 06-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 Gene3D G3DSA:3.40.50.1000 4 159 9.2E-49 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 8 155 1.1E-32 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CAK95_RS17585 c6a92eceb6b855ade00d4762d053b98d 173 PIRSF PIRSF004682 1 164 2.0E-56 T 06-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 Pfam PF00593 TonB dependent receptor 550 788 8.2E-29 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 SUPERFAMILY SSF56935 55 790 1.13E-121 T 06-07-2017 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 Pfam PF07715 TonB-dependent Receptor Plug Domain 90 188 5.5E-21 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 Gene3D G3DSA:2.40.170.20 204 790 9.0E-131 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 92 787 2.2E-80 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAK95_RS22745 6b2cd1f4082cd5266b05c2e1941997bf 790 Gene3D G3DSA:2.170.130.10 54 197 3.1E-34 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 PRINTS PR00173 Glutamate-aspartate symporter signature 90 115 2.8E-18 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 2.8E-18 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 PRINTS PR00173 Glutamate-aspartate symporter signature 308 334 2.8E-18 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 PRINTS PR00173 Glutamate-aspartate symporter signature 343 362 2.8E-18 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 Pfam PF00375 Sodium:dicarboxylate symporter family 25 416 1.3E-99 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 SUPERFAMILY SSF118215 25 417 1.07E-107 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 311 334 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 52 67 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 Gene3D G3DSA:1.10.3860.10 24 423 5.1E-103 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK95_RS14115 e8cb3c4db305ac33e72aa5804af12f5d 445 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 18 444 36.288 T 06-07-2017 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 SUPERFAMILY SSF47384 85 143 4.12E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 SUPERFAMILY SSF52172 183 320 1.01E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 Gene3D G3DSA:1.10.287.130 89 140 7.4E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 SMART SM00044 316 513 1.7E-63 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 Gene3D G3DSA:3.30.70.1230 343 524 1.5E-66 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 346 523 2.0E-57 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 Pfam PF00072 Response regulator receiver domain 183 295 4.8E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 SMART SM00448 181 294 1.3E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 Gene3D G3DSA:3.40.50.2300 182 307 1.9E-40 T 06-07-2017 CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 SUPERFAMILY SSF55073 343 522 4.4E-61 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS04650 9a9d25623448cea9c3aa30ae58620fb7 527 ProSitePatterns PS00452 Guanylate cyclase signature. 456 479 - T 06-07-2017 IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site GO:0009190|GO:0016849|GO:0035556 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 Gene3D G3DSA:3.90.470.20 1 127 7.7E-35 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 101 3.7E-17 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 129 24.213 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 99 2.0E-35 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 129 1.6E-27 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 SUPERFAMILY SSF56214 1 126 2.49E-26 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK95_RS22340 3c1233a8440676337be88d2beed161e2 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 125 1.3E-20 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.4E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 Gene3D G3DSA:1.10.10.10 1 86 2.7E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 Pfam PF03466 LysR substrate binding domain 87 291 3.1E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 Gene3D G3DSA:3.40.190.10 178 257 2.8E-5 T 06-07-2017 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 Gene3D G3DSA:3.40.190.10 91 177 6.0E-25 T 06-07-2017 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 SUPERFAMILY SSF53850 89 295 4.71E-42 T 06-07-2017 CAK95_RS13750 6b85f9bb0ebcb7cd3a47acb21c487659 297 SUPERFAMILY SSF46785 1 111 5.53E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 PRINTS PR00069 Aldo-keto reductase signature 33 57 6.2E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 PRINTS PR00069 Aldo-keto reductase signature 89 107 6.2E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 PRINTS PR00069 Aldo-keto reductase signature 154 183 6.2E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 PRINTS PR00069 Aldo-keto reductase signature 191 215 6.2E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 PRINTS PR00069 Aldo-keto reductase signature 120 137 6.2E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 Gene3D G3DSA:3.20.20.100 7 260 7.0E-90 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 Pfam PF00248 Aldo/keto reductase family 14 189 6.7E-42 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 Pfam PF00248 Aldo/keto reductase family 197 255 8.7E-10 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS21765 c33a0953f25e24875f68a6d1f4eab384 272 SUPERFAMILY SSF51430 5 265 6.81E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 62 72 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 76 92 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 46 61 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 112 120 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 95 105 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 PRINTS PR00604 Class IA and IB cytochrome C signature 33 40 1.2E-27 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 SUPERFAMILY SSF46626 21 122 3.98E-33 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 Pfam PF00034 Cytochrome c 24 120 8.9E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23495 1bba903920e16ec1f589cb5366bcaa5a 129 Gene3D G3DSA:1.10.760.10 21 123 1.7E-39 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS28295 11fd3be8ab3d78d0cfd0eef4bc802777 393 Gene3D G3DSA:1.20.1250.20 12 190 2.9E-13 T 06-07-2017 CAK95_RS28295 11fd3be8ab3d78d0cfd0eef4bc802777 393 Gene3D G3DSA:1.20.1250.20 218 388 1.2E-6 T 06-07-2017 CAK95_RS28295 11fd3be8ab3d78d0cfd0eef4bc802777 393 Pfam PF07690 Major Facilitator Superfamily 20 299 1.9E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS28295 11fd3be8ab3d78d0cfd0eef4bc802777 393 SUPERFAMILY SSF103473 8 389 1.83E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 Gene3D G3DSA:3.30.420.10 3 183 3.2E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 SUPERFAMILY SSF47819 190 295 1.26E-22 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 SUPERFAMILY SSF47819 302 366 2.62E-12 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 SMART SM00474 1 170 3.1E-32 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 TIGRFAM TIGR01388 rnd: ribonuclease D 3 363 2.8E-121 T 06-07-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 SUPERFAMILY SSF53098 3 203 8.28E-66 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 Hamap MF_01899 Ribonuclease D [rnd]. 1 364 43.716 T 06-07-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 Pfam PF00570 HRDC domain 212 264 2.5E-10 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK95_RS25695 e7ca16257bac05942ffc04f1798fb242 382 Pfam PF01612 3'-5' exonuclease 4 170 5.9E-36 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 278 390 2.6E-17 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Gene3D G3DSA:3.40.120.10 191 268 4.7E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Gene3D G3DSA:3.40.120.10 269 390 1.7E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 SUPERFAMILY SSF53738 278 387 4.71E-19 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 175 272 4.1E-26 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 413 486 4.8E-7 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Gene3D G3DSA:3.40.120.10 26 154 3.8E-22 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 SUPERFAMILY SSF55957 390 488 6.54E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 27 158 1.1E-22 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 Gene3D G3DSA:3.30.310.50 392 488 9.9E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 SUPERFAMILY SSF53738 20 158 5.1E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 115 129 1.2E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 189 208 1.2E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 252 267 1.2E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 223 236 1.2E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS06750 88f52fc18a6eb81d06ab6392228512f5 499 SUPERFAMILY SSF53738 174 273 7.06E-27 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Gene3D G3DSA:2.40.110.10 291 394 1.9E-26 T 06-07-2017 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 292 391 3.6E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 SUPERFAMILY SSF56645 164 416 1.57E-64 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 406 555 5.8E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 SUPERFAMILY SSF47203 405 557 1.93E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 513 532 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Gene3D G3DSA:1.20.140.10 395 556 2.8E-55 T 06-07-2017 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Gene3D G3DSA:1.10.540.10 168 286 9.3E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS11920 f35615f5996012860a494b21ae99db3e 559 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 174 285 1.5E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 164 1.0E-14 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 SUPERFAMILY SSF55326 7 170 6.73E-49 T 06-07-2017 CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 348 43.814 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 343 1.5E-35 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 SUPERFAMILY SSF56042 174 344 4.45E-57 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 338 7.4E-131 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 Gene3D G3DSA:3.30.1330.10 22 170 1.7E-60 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK95_RS25745 d17ca4a4dc49d19b1ceb0ff322ff5413 356 Gene3D G3DSA:3.90.650.10 174 346 9.8E-64 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Gene3D G3DSA:1.10.760.10 329 427 1.1E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Pfam PF00400 WD domain, G-beta repeat 105 139 1.6E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Pfam PF00400 WD domain, G-beta repeat 147 180 1.9E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Pfam PF00400 WD domain, G-beta repeat 266 303 0.0025 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Pfam PF00034 Cytochrome c 329 424 2.2E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SUPERFAMILY SSF50978 16 303 7.69E-66 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 Gene3D G3DSA:2.130.10.10 22 309 1.2E-67 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 222 261 0.19 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 264 303 2.1E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 18 57 0.01 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 142 181 1.1E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 101 140 1.1E-10 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 185 220 35.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SMART SM00320 60 98 1.6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00604 Class IA and IB cytochrome C signature 349 364 5.4E-9 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00604 Class IA and IB cytochrome C signature 365 375 5.4E-9 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00604 Class IA and IB cytochrome C signature 336 343 5.4E-9 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00604 Class IA and IB cytochrome C signature 379 395 5.4E-9 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00604 Class IA and IB cytochrome C signature 399 409 5.4E-9 T 06-07-2017 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00320 G protein beta WD-40 repeat signature 168 182 3.5E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00320 G protein beta WD-40 repeat signature 127 141 3.5E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 PRINTS PR00320 G protein beta WD-40 repeat signature 290 304 3.5E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat CAK95_RS27875 96bc2b222fcca972bad86c59a4c9cf23 429 SUPERFAMILY SSF46626 329 424 2.44E-22 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03350 f531b538539c38e251c0adf32f3d2b80 357 SUPERFAMILY SSF53850 129 318 1.19E-8 T 06-07-2017 CAK95_RS03350 f531b538539c38e251c0adf32f3d2b80 357 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 81 350 1.5E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS03350 f531b538539c38e251c0adf32f3d2b80 357 PIRSF PIRSF017082 28 355 5.7E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 SUPERFAMILY SSF52518 17 237 3.28E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 Gene3D G3DSA:3.40.50.970 402 634 9.7E-20 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 SUPERFAMILY SSF54862 584 666 3.2E-5 T 06-07-2017 CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 Gene3D G3DSA:3.40.50.970 23 199 2.5E-14 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 439 580 3.6E-15 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS06230 e4b6fb6413edf591265d8d48719ce489 715 SUPERFAMILY SSF52518 405 590 1.71E-21 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS08880 f81ec6d44f44e6b928ea85c0aaf72c49 192 Gene3D G3DSA:3.90.950.10 1 186 1.7E-63 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS08880 f81ec6d44f44e6b928ea85c0aaf72c49 192 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 188 41.589 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 CAK95_RS08880 f81ec6d44f44e6b928ea85c0aaf72c49 192 Pfam PF01725 Ham1 family 12 184 1.2E-41 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAK95_RS08880 f81ec6d44f44e6b928ea85c0aaf72c49 192 SUPERFAMILY SSF52972 2 186 1.36E-54 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF56784 539 788 3.81E-54 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF56784 480 500 3.81E-54 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF81665 730 760 6.15E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF81665 248 283 6.15E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF81665 381 476 6.15E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Gene3D G3DSA:3.40.50.1000 453 496 1.1E-52 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Gene3D G3DSA:3.40.50.1000 609 749 1.1E-52 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 191 210 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 269 287 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 465 480 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 403 417 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 658 675 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00943 Copper-transporting ATPase signature 249 268 7.7E-13 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 187 791 7.8E-179 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Gene3D G3DSA:2.70.150.10 206 380 8.3E-30 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 638 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 496 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 704 716 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 617 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 700 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 1.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Gene3D G3DSA:3.40.1110.10 497 608 2.8E-24 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 251 759 1.3E-88 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Pfam PF04945 YHS domain 36 81 2.7E-18 T 06-07-2017 IPR007029 YHS domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SMART SM00746 38 76 2.5E-7 T 06-07-2017 IPR011017 TRASH domain CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 478 695 2.0E-41 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF47240 35 80 7.84E-9 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 206 790 1.1E-186 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 SUPERFAMILY SSF81653 287 380 5.1E-27 T 06-07-2017 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 Pfam PF00122 E1-E2 ATPase 250 473 3.1E-66 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS20670 0fbd3ceea984831aed7fa867384c63b4 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 484 490 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS18815 4cf0a99f3b028213b1c3d15439b99d50 119 Pfam PF12680 SnoaL-like domain 3 101 2.4E-8 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS18815 4cf0a99f3b028213b1c3d15439b99d50 119 Gene3D G3DSA:3.10.450.50 3 106 7.5E-12 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS18815 4cf0a99f3b028213b1c3d15439b99d50 119 SUPERFAMILY SSF54427 3 111 1.38E-18 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS18455 4ee4edffe39df90b81ca5dad14ad4294 332 Pfam PF09084 NMT1/THI5 like 41 249 1.2E-17 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS18455 4ee4edffe39df90b81ca5dad14ad4294 332 Gene3D G3DSA:3.40.190.10 124 202 2.9E-10 T 06-07-2017 CAK95_RS18455 4ee4edffe39df90b81ca5dad14ad4294 332 SUPERFAMILY SSF53850 34 261 1.85E-31 T 06-07-2017 CAK95_RS23150 af51886e2cda92f6cea4c87b4a7a4be4 159 SUPERFAMILY SSF55620 30 147 8.15E-26 T 06-07-2017 CAK95_RS23150 af51886e2cda92f6cea4c87b4a7a4be4 159 Gene3D G3DSA:3.30.1130.10 18 143 1.4E-45 T 06-07-2017 CAK95_RS23150 af51886e2cda92f6cea4c87b4a7a4be4 159 Pfam PF14489 QueF-like protein 63 140 1.0E-32 T 06-07-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAK95_RS23150 af51886e2cda92f6cea4c87b4a7a4be4 159 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 159 68.334 T 06-07-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAK95_RS23150 af51886e2cda92f6cea4c87b4a7a4be4 159 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 29 137 7.1E-46 T 06-07-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 SUPERFAMILY SSF48150 16 232 2.2E-72 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Gene3D G3DSA:3.90.79.10 242 355 1.0E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Pfam PF14815 NUDIX domain 245 353 1.9E-20 T 06-07-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Gene3D G3DSA:1.10.340.30 39 134 1.1E-43 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 202 218 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Pfam PF00633 Helix-hairpin-helix motif 112 139 5.5E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Gene3D G3DSA:1.10.1670.10 135 234 2.1E-38 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 17 277 7.3E-95 T 06-07-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 SUPERFAMILY SSF55811 230 356 2.43E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 166 1.3E-19 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 SMART SM00478 51 200 4.9E-51 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS11285 ccdf9d09076c09fd9677800a9f66e222 357 ProSitePatterns PS01155 Endonuclease III family signature. 114 143 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00388 768 837 8.2E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Pfam PF13188 PAS domain 22 50 0.03 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Pfam PF13188 PAS domain 525 559 2.1E-4 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Gene3D G3DSA:1.10.287.130 760 822 2.1E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Gene3D G3DSA:3.30.565.10 823 993 7.2E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00091 129 198 240.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00091 12 81 240.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00091 633 699 4.5E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00091 520 586 270.0 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SMART SM00387 883 994 1.6E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SUPERFAMILY SSF47384 755 839 1.75E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SUPERFAMILY SSF55785 644 755 8.03E-21 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 921 935 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 978 991 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 954 972 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 634 755 2.6E-20 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 SUPERFAMILY SSF55874 826 992 9.56E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Pfam PF13426 PAS domain 644 746 1.9E-12 T 06-07-2017 IPR000014 PAS domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Gene3D G3DSA:3.30.450.20 633 746 7.4E-20 T 06-07-2017 CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 884 992 6.7E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12655 63f005507bed2d393c794532d3e29d9b 998 Pfam PF00512 His Kinase A (phospho-acceptor) domain 768 837 1.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 267 8.1E-79 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 SUPERFAMILY SSF55347 129 238 6.54E-35 T 06-07-2017 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 127 7.2E-34 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 130 266 4.2E-43 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 SUPERFAMILY SSF51735 4 128 7.65E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 SUPERFAMILY SSF51735 238 269 7.65E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 PIRSF PIRSF000161 2 270 5.3E-78 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 267 32.37 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS08950 0fd54bdd5113689f91b45199e1c4e428 271 Gene3D G3DSA:3.40.50.720 2 165 6.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 SMART SM00842 23 219 8.3E-65 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.30.1490.110 106 187 7.8E-14 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 23 404 1.3E-89 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.30.420.40 13 105 3.9E-16 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.30.420.40 191 232 3.9E-16 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.30.420.40 324 378 3.1E-20 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.30.420.40 233 257 3.1E-20 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 SUPERFAMILY SSF53067 22 220 7.77E-40 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Hamap MF_02033 Cell division protein FtsA [ftsA]. 19 440 25.311 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 SUPERFAMILY SSF53067 222 404 8.87E-40 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Pfam PF02491 SHS2 domain inserted in FTSA 112 185 1.3E-14 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Gene3D G3DSA:3.90.640.10 258 323 2.8E-15 T 06-07-2017 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 PIRSF PIRSF003101 14 440 1.0E-113 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAK95_RS01760 50bacf32f0b670fc1151b26e8e587666 440 Pfam PF14450 Cell division protein FtsA 230 400 3.1E-21 T 06-07-2017 CAK95_RS12520 96b2a885cf7c64b6bf66e95015abc070 112 SUPERFAMILY SSF50022 8 106 1.57E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS12520 96b2a885cf7c64b6bf66e95015abc070 112 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 105 2.3E-30 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAK95_RS12520 96b2a885cf7c64b6bf66e95015abc070 112 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 104 6.7E-16 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAK95_RS12520 96b2a885cf7c64b6bf66e95015abc070 112 Gene3D G3DSA:2.102.10.10 5 107 1.8E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.40.50.800 544 644 2.4E-26 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 219 3.2E-12 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.30.930.10 242 543 1.6E-111 T 06-07-2017 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 647 32.162 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 SUPERFAMILY SSF52954 540 644 3.78E-26 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 SUPERFAMILY SSF55681 243 538 2.37E-86 T 06-07-2017 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Pfam PF02824 TGS domain 5 60 1.2E-7 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.30.980.10 67 129 2.1E-40 T 06-07-2017 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.30.980.10 187 224 2.1E-40 T 06-07-2017 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 SUPERFAMILY SSF81271 3 60 5.56E-14 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Pfam PF03129 Anticodon binding domain 555 643 3.7E-16 T 06-07-2017 IPR004154 Anticodon-binding CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 SUPERFAMILY SSF55186 63 241 4.84E-62 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 643 2.3E-198 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 327 542 5.4E-39 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.30.54.20 130 186 9.8E-24 T 06-07-2017 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 SMART SM00863 169 219 2.0E-22 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 PRINTS PR01047 Threonyl-tRNA synthetase signature 367 390 1.3E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 PRINTS PR01047 Threonyl-tRNA synthetase signature 477 505 1.3E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 PRINTS PR01047 Threonyl-tRNA synthetase signature 547 559 1.3E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 PRINTS PR01047 Threonyl-tRNA synthetase signature 334 362 1.3E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 PRINTS PR01047 Threonyl-tRNA synthetase signature 520 533 1.3E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK95_RS20780 89610dfd24f00580db7a6db87257c8f2 657 Gene3D G3DSA:3.10.20.30 1 64 3.7E-21 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS05535 5308608f5debf85535df7bababe96833 181 Pfam PF00430 ATP synthase B/B' CF(0) 33 162 1.6E-22 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK95_RS05535 5308608f5debf85535df7bababe96833 181 Hamap MF_01398 ATP synthase subunit b [atpF]. 24 179 9.818 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 PIRSF PIRSF036626 1 539 1.1E-231 T 06-07-2017 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 SMART SM00852 171 304 2.6E-8 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 Gene3D G3DSA:3.90.550.10 342 539 1.7E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 Pfam PF12804 MobA-like NTP transferase domain 345 506 1.3E-38 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 Gene3D G3DSA:3.40.980.10 159 304 7.5E-14 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 Pfam PF00994 Probable molybdopterin binding domain 182 289 5.3E-6 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 SUPERFAMILY SSF53448 343 530 7.21E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 SUPERFAMILY SSF53218 181 308 1.23E-17 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20415 b738ac727a3797d535b400183398e95c 540 Gene3D G3DSA:3.90.105.10 20 51 1.3E-6 T 06-07-2017 CAK95_RS00520 9d7d79fd0cacdaa3dc7ef85ca14c3bbc 149 Pfam PF04480 Protein of unknown function (DUF559) 23 128 1.2E-36 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK95_RS00520 9d7d79fd0cacdaa3dc7ef85ca14c3bbc 149 SUPERFAMILY SSF52980 16 131 3.91E-20 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS14165 1047a0946f0fe65792092d2790ee4e4c 151 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 147 2.6E-20 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS14165 1047a0946f0fe65792092d2790ee4e4c 151 SUPERFAMILY SSF55961 2 149 3.34E-26 T 06-07-2017 CAK95_RS14165 1047a0946f0fe65792092d2790ee4e4c 151 Gene3D G3DSA:3.30.530.20 2 149 7.8E-31 T 06-07-2017 IPR023393 START-like domain CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 Pfam PF00909 Ammonium Transporter Family 38 479 4.7E-107 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 SUPERFAMILY SSF111352 219 459 8.63E-121 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 SUPERFAMILY SSF111352 32 185 8.63E-121 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 ProSitePatterns PS01219 Ammonium transporters signature. 228 253 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 Gene3D G3DSA:1.10.3430.10 219 459 6.9E-140 T 06-07-2017 IPR029020 Ammonium/urea transporter CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 Gene3D G3DSA:1.10.3430.10 30 184 6.9E-140 T 06-07-2017 IPR029020 Ammonium/urea transporter CAK95_RS08575 f137b8b360b3a764c7251f853d3b9c0a 481 TIGRFAM TIGR00836 amt: ammonium transporter 36 479 2.2E-125 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 Gene3D G3DSA:3.40.718.10 4 335 1.5E-119 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 Pfam PF02504 Fatty acid synthesis protein 5 328 5.3E-101 T 06-07-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 346 140.649 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 PIRSF PIRSF002465 3 340 4.1E-116 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 SUPERFAMILY SSF53659 5 335 5.76E-99 T 06-07-2017 CAK95_RS22510 8bd5bb89d5d3c54bc972573d092e1c53 356 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 5 335 5.1E-93 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAK95_RS13470 56e28bc9b651c2db85f71f8aac76030b 161 SUPERFAMILY SSF54637 3 157 7.99E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS13470 56e28bc9b651c2db85f71f8aac76030b 161 Pfam PF01575 MaoC like domain 21 122 1.1E-8 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS13470 56e28bc9b651c2db85f71f8aac76030b 161 Gene3D G3DSA:3.10.129.10 2 157 1.7E-35 T 06-07-2017 IPR029069 HotDog domain CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Gene3D G3DSA:3.10.20.30 2 75 1.1E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 198 333 1.5E-13 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Pfam PF01799 [2Fe-2S] binding domain 74 145 7.2E-22 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 SUPERFAMILY SSF47741 84 154 6.28E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 SUPERFAMILY SSF55961 195 336 2.16E-17 T 06-07-2017 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Gene3D G3DSA:1.10.150.120 76 152 2.4E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 SUPERFAMILY SSF54292 2 78 1.57E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 61 1.4E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS00415 d8dd0a66eb3cf50d36c3ae66dc8327e3 372 Gene3D G3DSA:3.30.530.20 194 347 5.5E-27 T 06-07-2017 IPR023393 START-like domain CAK95_RS15775 91ef94d1817ce94ecdd19911d209ef3d 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 3.0E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15775 91ef94d1817ce94ecdd19911d209ef3d 326 SUPERFAMILY SSF53850 101 292 1.72E-13 T 06-07-2017 CAK95_RS15775 91ef94d1817ce94ecdd19911d209ef3d 326 PIRSF PIRSF017082 1 325 1.0E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13870 53d2cd2837c87430025f4c08d58a7076 216 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 128 1.9E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS13870 53d2cd2837c87430025f4c08d58a7076 216 Gene3D G3DSA:2.30.110.10 35 162 2.5E-27 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS13870 53d2cd2837c87430025f4c08d58a7076 216 SUPERFAMILY SSF50475 38 168 2.01E-16 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS14690 4d648c4f5cec43ee091b71757f2be4c6 145 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 7.2E-32 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS14690 4d648c4f5cec43ee091b71757f2be4c6 145 SUPERFAMILY SSF46785 1 136 1.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14690 4d648c4f5cec43ee091b71757f2be4c6 145 Pfam PF02082 Transcriptional regulator 1 82 1.3E-25 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS14690 4d648c4f5cec43ee091b71757f2be4c6 145 Gene3D G3DSA:1.10.10.10 1 138 8.3E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03490 3b4cffb12af07112200e187002860f59 119 Gene3D G3DSA:3.90.1680.10 30 116 4.9E-25 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS03490 3b4cffb12af07112200e187002860f59 119 SUPERFAMILY SSF143081 30 116 6.8E-28 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS03490 3b4cffb12af07112200e187002860f59 119 Pfam PF02586 SOS response associated peptidase (SRAP) 30 106 7.6E-20 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS15475 be9ba9489de6ed1524ccb97fc560ae80 122 SMART SM00448 1 111 1.7E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15475 be9ba9489de6ed1524ccb97fc560ae80 122 Gene3D G3DSA:3.40.50.2300 2 118 3.9E-30 T 06-07-2017 CAK95_RS15475 be9ba9489de6ed1524ccb97fc560ae80 122 Pfam PF00072 Response regulator receiver domain 2 111 5.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15475 be9ba9489de6ed1524ccb97fc560ae80 122 SUPERFAMILY SSF52172 2 116 2.99E-30 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS05315 64981a139d93adb672f7ee267033ad3a 156 Pfam PF11164 Protein of unknown function (DUF2948) 4 141 2.8E-50 T 06-07-2017 IPR021335 Protein of unknown function DUF2948 CAK95_RS26385 b76dc86d74443ac2d2dd7212a0281e90 108 Pfam PF00893 Small Multidrug Resistance protein 6 97 5.4E-24 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAK95_RS26385 b76dc86d74443ac2d2dd7212a0281e90 108 SUPERFAMILY SSF103481 9 106 4.84E-16 T 06-07-2017 CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 Gene3D G3DSA:3.40.50.720 11 255 9.5E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 192 0.0053 T 06-07-2017 CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 SUPERFAMILY SSF51735 11 255 3.27E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16185 89842c12c616548a62e12f5d4fa3019b 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 254 2.3E-58 T 06-07-2017 CAK95_RS16155 ac4aaf6500b55ca21dc5fda27f1d36d8 144 SUPERFAMILY SSF51182 17 126 4.98E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS16155 ac4aaf6500b55ca21dc5fda27f1d36d8 144 Gene3D G3DSA:2.60.120.10 35 123 6.0E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 SUPERFAMILY SSF55931 135 491 2.26E-85 T 06-07-2017 CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 SUPERFAMILY SSF54368 19 133 1.11E-14 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 Gene3D G3DSA:3.30.590.10 136 466 8.0E-78 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 Gene3D G3DSA:3.10.20.70 19 134 3.8E-12 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 Pfam PF00120 Glutamine synthetase, catalytic domain 135 469 3.1E-77 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS12545 4b3e191a55ac11d04e905a8fe2a11d4a 493 SMART SM01230 133 400 8.3E-77 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 521 685 5.0E-32 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 396 519 1.2E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Pfam PF07696 7TMR-DISM extracellular 2 76 168 3.9E-6 T 06-07-2017 IPR011622 7TM-DISM receptor, extracellular domain, type 2 CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Gene3D G3DSA:3.20.20.450 699 949 1.4E-91 T 06-07-2017 IPR001633 EAL domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Pfam PF00990 Diguanylate cyclase, GGDEF domain 523 680 8.6E-36 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SMART SM00086 470 512 2.6E-8 T 06-07-2017 IPR001610 PAC motif CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Pfam PF00563 EAL domain 701 937 8.7E-68 T 06-07-2017 IPR001633 EAL domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SMART SM00091 395 463 3.0E-4 T 06-07-2017 IPR000014 PAS domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SMART SM00267 512 685 1.8E-45 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SUPERFAMILY SSF55785 404 514 6.6E-22 T 06-07-2017 IPR000014 PAS domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SUPERFAMILY SSF141868 700 950 1.83E-80 T 06-07-2017 IPR001633 EAL domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Pfam PF08447 PAS fold 418 505 3.4E-17 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Gene3D G3DSA:3.30.450.20 397 510 4.3E-26 T 06-07-2017 CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 Gene3D G3DSA:3.30.70.270 525 691 3.4E-46 T 06-07-2017 CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SMART SM00052 695 942 7.7E-105 T 06-07-2017 IPR001633 EAL domain CAK95_RS04245 7e11ad6940b5f3879c96186a7ab63c55 957 SUPERFAMILY SSF55073 528 685 1.33E-39 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 Gene3D G3DSA:3.30.1360.120 158 251 1.5E-24 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 Gene3D G3DSA:3.30.1360.120 34 58 1.5E-24 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 Gene3D G3DSA:3.30.70.1400 59 131 4.3E-8 T 06-07-2017 CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 315 435 1.4E-7 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 Pfam PF01571 Aminomethyltransferase folate-binding domain 32 254 3.3E-44 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 SUPERFAMILY SSF103025 291 327 8.16E-54 T 06-07-2017 CAK95_RS06145 9d9c0637458e7eb49adbf7c074b3384c 467 SUPERFAMILY SSF103025 14 255 8.16E-54 T 06-07-2017 CAK95_RS22380 58eadcf8783b9b638455c8a9826587d2 246 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 107 236 3.7E-35 T 06-07-2017 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 CAK95_RS22380 58eadcf8783b9b638455c8a9826587d2 246 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 17 87 3.0E-15 T 06-07-2017 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 CAK95_RS22380 58eadcf8783b9b638455c8a9826587d2 246 SUPERFAMILY SSF55729 83 242 1.43E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS22380 58eadcf8783b9b638455c8a9826587d2 246 PIRSF PIRSF037208 1 246 4.5E-82 T 06-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic CAK95_RS22380 58eadcf8783b9b638455c8a9826587d2 246 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 245 42.467 T 06-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.5E-39 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.5E-39 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.5E-39 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.5E-39 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 SUPERFAMILY SSF54686 1 134 5.63E-56 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.6E-50 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 7.4E-57 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.052 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21300 4b80195925fdc91d4544563d387171da 137 Gene3D G3DSA:3.90.1170.10 23 134 1.5E-52 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK95_RS27125 817e5291709d3268535748c4e8eab831 257 Pfam PF00005 ABC transporter 23 161 1.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27125 817e5291709d3268535748c4e8eab831 257 Gene3D G3DSA:3.40.50.300 1 219 9.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27125 817e5291709d3268535748c4e8eab831 257 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27125 817e5291709d3268535748c4e8eab831 257 SMART SM00382 31 211 2.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27125 817e5291709d3268535748c4e8eab831 257 SUPERFAMILY SSF52540 1 229 4.32E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06205 9db1e88dd266f883417eae985dbead64 140 SUPERFAMILY SSF54637 3 138 4.3E-25 T 06-07-2017 IPR029069 HotDog domain CAK95_RS06205 9db1e88dd266f883417eae985dbead64 140 Gene3D G3DSA:3.10.129.10 6 138 2.4E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS06205 9db1e88dd266f883417eae985dbead64 140 Pfam PF03061 Thioesterase superfamily 19 100 5.8E-9 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS10200 34bbac305c64e3da524bbe4511ec1e79 261 SMART SM00382 34 215 3.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10200 34bbac305c64e3da524bbe4511ec1e79 261 Pfam PF00005 ABC transporter 25 164 1.8E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10200 34bbac305c64e3da524bbe4511ec1e79 261 Gene3D G3DSA:3.40.50.300 3 222 2.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10200 34bbac305c64e3da524bbe4511ec1e79 261 SUPERFAMILY SSF52540 4 235 7.84E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06895 2553a169c70c8e8dcea528ebfd24f4a1 204 Pfam PF02627 Carboxymuconolactone decarboxylase family 49 130 1.4E-13 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS06895 2553a169c70c8e8dcea528ebfd24f4a1 204 SUPERFAMILY SSF69118 11 187 4.44E-45 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS06895 2553a169c70c8e8dcea528ebfd24f4a1 204 Gene3D G3DSA:1.20.1290.10 36 183 1.4E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS21535 48138a368876b3cef92202cfadb25eef 87 SUPERFAMILY SSF160544 5 80 1.11E-21 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAK95_RS21535 48138a368876b3cef92202cfadb25eef 87 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 77 1.1E-20 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAK95_RS21535 48138a368876b3cef92202cfadb25eef 87 Gene3D G3DSA:3.40.1690.10 5 79 6.9E-24 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 272 1.3E-83 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 Gene3D G3DSA:1.20.140.10 265 479 2.9E-39 T 06-07-2017 CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 479 4.9E-54 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 PIRSF PIRSF000331 2 488 8.0E-122 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 Gene3D G3DSA:2.40.110.10 146 264 6.4E-41 T 06-07-2017 CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 Gene3D G3DSA:1.10.3140.10 5 145 1.1E-38 T 06-07-2017 CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 SUPERFAMILY SSF47203 263 480 1.59E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS10715 b0de368960f2969d694ae3375bd2a4be 498 SUPERFAMILY SSF56645 5 273 1.44E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS18130 b453490503e3cadeed0ee9586890de3e 500 SUPERFAMILY SSF64518 1 500 4.97E-31 T 06-07-2017 CAK95_RS18130 b453490503e3cadeed0ee9586890de3e 500 Pfam PF00669 Bacterial flagellin N-terminal helical region 12 134 3.2E-5 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS02905 86796930ac169b21fc34d8057201aeb2 269 Pfam PF13531 Bacterial extracellular solute-binding protein 33 265 9.3E-47 T 06-07-2017 CAK95_RS02905 86796930ac169b21fc34d8057201aeb2 269 Gene3D G3DSA:3.40.190.10 177 264 2.2E-10 T 06-07-2017 CAK95_RS02905 86796930ac169b21fc34d8057201aeb2 269 Gene3D G3DSA:3.40.190.10 31 155 3.6E-22 T 06-07-2017 CAK95_RS02905 86796930ac169b21fc34d8057201aeb2 269 SUPERFAMILY SSF53850 29 265 8.9E-42 T 06-07-2017 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 380 488 2.4E-11 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 9 26 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 SUPERFAMILY SSF51905 3 323 4.21E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 78 90 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 313 319 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 6.9E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 Pfam PF01266 FAD dependent oxidoreductase 5 323 2.2E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS03865 e5e2ee9507bddc23bfd7480ba3af69bb 499 Gene3D G3DSA:3.50.50.60 3 239 5.6E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09710 fb80b057008acea8119bc1b3b34e78c3 159 Gene3D G3DSA:3.30.530.20 6 156 2.9E-20 T 06-07-2017 IPR023393 START-like domain CAK95_RS09710 fb80b057008acea8119bc1b3b34e78c3 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 154 2.6E-14 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS09710 fb80b057008acea8119bc1b3b34e78c3 159 SUPERFAMILY SSF55961 8 156 1.33E-41 T 06-07-2017 CAK95_RS12045 20566572f5d13ec4b15ee918de2ba997 149 SUPERFAMILY SSF55961 12 147 1.95E-42 T 06-07-2017 CAK95_RS12045 20566572f5d13ec4b15ee918de2ba997 149 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 148 4.2E-31 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS12045 20566572f5d13ec4b15ee918de2ba997 149 Gene3D G3DSA:3.30.530.20 6 148 1.2E-44 T 06-07-2017 IPR023393 START-like domain CAK95_RS07020 a992f6171dd43da59410c06ba26ac2f9 589 SUPERFAMILY SSF56176 495 566 2.04E-7 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS07020 a992f6171dd43da59410c06ba26ac2f9 589 Pfam PF00999 Sodium/hydrogen exchanger family 12 390 1.2E-43 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK95_RS07020 a992f6171dd43da59410c06ba26ac2f9 589 Pfam PF03471 Transporter associated domain 495 567 2.4E-8 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS07020 a992f6171dd43da59410c06ba26ac2f9 589 Gene3D G3DSA:3.30.465.10 495 566 8.1E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS07020 a992f6171dd43da59410c06ba26ac2f9 589 SMART SM01091 490 569 6.6E-7 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 Pfam PF00005 ABC transporter 25 173 4.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 Pfam PF00005 ABC transporter 276 432 3.8E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 SMART SM00382 34 221 2.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 SUPERFAMILY SSF52540 260 491 2.71E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 SUPERFAMILY SSF52540 3 230 2.27E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 Gene3D G3DSA:3.40.50.300 8 233 2.7E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28620 295fe191c4c3bf342f95f677eb8a2a45 506 Gene3D G3DSA:3.40.50.300 260 490 5.1E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 SUPERFAMILY SSF49503 175 327 6.42E-32 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 Pfam PF07731 Multicopper oxidase 217 331 3.2E-20 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 Pfam PF07732 Multicopper oxidase 88 192 1.5E-35 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 Gene3D G3DSA:2.60.40.420 194 327 1.1E-26 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 ProSitePatterns PS00080 Multicopper oxidases signature 2. 316 327 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 Gene3D G3DSA:2.60.40.420 46 191 4.7E-36 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS02410 8b966f8df19765d6251a4de01adb5cc2 463 SUPERFAMILY SSF49503 51 195 1.45E-36 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS07725 f806a34625785a63124d2e9881d5032d 204 Pfam PF01810 LysE type translocator 15 200 4.4E-30 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS07725 f806a34625785a63124d2e9881d5032d 204 PIRSF PIRSF006324 1 203 9.7E-49 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS11565 695bf4a80e7c24263275180780d71d65 423 Gene3D G3DSA:3.40.190.10 139 153 3.1E-5 T 06-07-2017 CAK95_RS11565 695bf4a80e7c24263275180780d71d65 423 Gene3D G3DSA:3.40.190.10 33 107 3.1E-5 T 06-07-2017 CAK95_RS11565 695bf4a80e7c24263275180780d71d65 423 SUPERFAMILY SSF53850 26 412 1.84E-60 T 06-07-2017 CAK95_RS11565 695bf4a80e7c24263275180780d71d65 423 Pfam PF01547 Bacterial extracellular solute-binding protein 40 328 1.7E-35 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAK95_RS11565 695bf4a80e7c24263275180780d71d65 423 Gene3D G3DSA:3.40.190.10 154 348 1.5E-31 T 06-07-2017 CAK95_RS10570 3a5abe2e704acba2a7b0187ec018ef97 220 SUPERFAMILY SSF141259 26 97 1.27E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS10570 3a5abe2e704acba2a7b0187ec018ef97 220 Pfam PF02559 CarD-like/TRCF domain 32 139 4.6E-14 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS10570 3a5abe2e704acba2a7b0187ec018ef97 220 SMART SM01058 31 141 1.8E-34 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK95_RS20845 bd5547d83e0f688598ed7643ca1687f3 295 Gene3D G3DSA:3.40.50.720 1 281 1.6E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20845 bd5547d83e0f688598ed7643ca1687f3 295 SUPERFAMILY SSF51735 1 283 1.26E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20845 bd5547d83e0f688598ed7643ca1687f3 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 73 4.4E-11 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 Gene3D G3DSA:3.40.50.720 118 298 3.4E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 SUPERFAMILY SSF52283 4 138 2.08E-28 T 06-07-2017 CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 297 4.4E-48 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 SUPERFAMILY SSF51735 106 297 4.3E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 Gene3D G3DSA:3.40.50.720 4 117 3.2E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23705 a22da296d691c51d957ee16f2e5cdf1e 351 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 329 9.6E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 437 581 7.9E-18 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 Gene3D G3DSA:3.30.70.20 620 665 4.5E-4 T 06-07-2017 CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 Gene3D G3DSA:3.40.50.970 28 201 7.4E-16 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 Gene3D G3DSA:3.40.50.970 477 619 8.5E-15 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 Gene3D G3DSA:3.40.50.970 405 457 8.9E-4 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 SUPERFAMILY SSF52518 403 630 1.56E-31 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 SUPERFAMILY SSF52518 26 247 1.23E-25 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00225 b4530693cf3941fc76c8c7a8b21249d3 713 PIRSF PIRSF006439 22 673 2.0E-94 T 06-07-2017 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 199.229 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 Pfam PF02272 DHHA1 domain 815 883 5.3E-14 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 703 2.3E-16 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 Pfam PF01411 tRNA synthetases class II (A) 6 555 1.9E-222 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 SMART SM00863 653 703 4.5E-18 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 SUPERFAMILY SSF55186 552 712 2.62E-48 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 1.4E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 1.4E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 1.4E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.4E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 1.4E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 869 3.0E-295 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 SUPERFAMILY SSF50447 453 549 3.26E-20 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 SUPERFAMILY SSF101353 247 461 9.55E-62 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 SUPERFAMILY SSF55681 4 245 6.21E-109 T 06-07-2017 CAK95_RS26595 f3858139c2a776a21592543f60bec8d1 889 Gene3D G3DSA:3.30.930.10 4 241 6.9E-114 T 06-07-2017 CAK95_RS04990 e835f5c5a5113ba3934eca3ef2d04d1d 248 Pfam PF00005 ABC transporter 24 165 1.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04990 e835f5c5a5113ba3934eca3ef2d04d1d 248 Gene3D G3DSA:3.40.50.300 3 220 1.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04990 e835f5c5a5113ba3934eca3ef2d04d1d 248 SUPERFAMILY SSF52540 4 243 7.48E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04990 e835f5c5a5113ba3934eca3ef2d04d1d 248 SMART SM00382 33 216 4.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04990 e835f5c5a5113ba3934eca3ef2d04d1d 248 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12010 247700be0dfa69840a9683ae9e46a2bb 141 SUPERFAMILY SSF54593 5 136 4.97E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS12010 247700be0dfa69840a9683ae9e46a2bb 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 134 3.3E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS12010 247700be0dfa69840a9683ae9e46a2bb 141 Gene3D G3DSA:3.10.180.10 14 136 4.2E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27025 a6bba0031e69e21178c4bca5a872d6a2 84 Gene3D G3DSA:1.10.260.40 6 57 1.7E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27025 a6bba0031e69e21178c4bca5a872d6a2 84 SMART SM00530 6 64 1.9E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS27025 a6bba0031e69e21178c4bca5a872d6a2 84 SUPERFAMILY SSF47413 3 58 1.36E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27025 a6bba0031e69e21178c4bca5a872d6a2 84 Pfam PF01381 Helix-turn-helix 7 48 2.8E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 Gene3D G3DSA:3.40.50.970 41 222 3.3E-38 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 441 586 1.4E-20 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 41 220 5.0E-40 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 SUPERFAMILY SSF52518 33 227 2.81E-36 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 Gene3D G3DSA:3.40.50.970 422 594 6.6E-33 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 Gene3D G3DSA:3.40.50.1220 235 421 2.2E-16 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 SUPERFAMILY SSF52467 204 393 8.72E-20 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS06240 50dd78209610846d38947ccc5b8b4cc4 595 SUPERFAMILY SSF52518 410 595 3.13E-32 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS25365 c767f16f56801b1665045e76b7b2103e 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 97 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS25365 c767f16f56801b1665045e76b7b2103e 150 SUPERFAMILY SSF46785 9 134 2.78E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25365 c767f16f56801b1665045e76b7b2103e 150 SMART SM00347 24 127 5.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25365 c767f16f56801b1665045e76b7b2103e 150 Gene3D G3DSA:1.10.10.10 11 132 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25365 c767f16f56801b1665045e76b7b2103e 150 Pfam PF13463 Winged helix DNA-binding domain 38 97 3.7E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 118 553 3.7E-120 T 06-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 ProSitePatterns PS00543 HlyD family secretion proteins signature. 517 539 - T 06-07-2017 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 Pfam PF13533 Biotin-lipoyl like 169 193 5.6E-6 T 06-07-2017 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 Gene3D G3DSA:2.40.50.100 161 192 8.9E-17 T 06-07-2017 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 Gene3D G3DSA:2.40.50.100 384 418 8.9E-17 T 06-07-2017 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 Pfam PF13437 HlyD family secretion protein 387 485 5.5E-15 T 06-07-2017 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 SUPERFAMILY SSF111369 161 221 1.27E-5 T 06-07-2017 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 432 456 3.9E-37 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 170 190 3.9E-37 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 456 479 3.9E-37 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 128 151 3.9E-37 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS10820 3318c95c1a0699b5d84fcbd8aba76d64 553 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 399 420 3.9E-37 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS14340 ba91a9d9696c3361a4767b4235c17a7a 233 Pfam PF04199 Putative cyclase 6 173 5.5E-30 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS14340 ba91a9d9696c3361a4767b4235c17a7a 233 Gene3D G3DSA:3.50.30.50 3 232 2.8E-55 T 06-07-2017 CAK95_RS14340 ba91a9d9696c3361a4767b4235c17a7a 233 SUPERFAMILY SSF102198 2 231 1.57E-53 T 06-07-2017 CAK95_RS14900 d0f567106f7e1f27ddd5d9367392d083 258 SUPERFAMILY SSF102198 2 256 8.37E-57 T 06-07-2017 CAK95_RS14900 d0f567106f7e1f27ddd5d9367392d083 258 Pfam PF04199 Putative cyclase 6 186 1.7E-35 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS14900 d0f567106f7e1f27ddd5d9367392d083 258 Gene3D G3DSA:3.50.30.50 2 257 2.8E-61 T 06-07-2017 CAK95_RS11575 c967ce228dddc4d8a78a7ddf7e6446f0 312 Gene3D G3DSA:1.10.3720.10 78 308 5.7E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11575 c967ce228dddc4d8a78a7ddf7e6446f0 312 SUPERFAMILY SSF161098 72 299 2.49E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11575 c967ce228dddc4d8a78a7ddf7e6446f0 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 309 1.9E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 SUPERFAMILY SSF51344 3 82 6.8E-24 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 3.0E-25 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 Gene3D G3DSA:2.60.15.10 3 89 2.1E-31 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 125 19.974 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 116 6.3E-29 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS07365 df27ca238025cc8508d9956b7f2baed3 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 9.1E-28 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK95_RS19680 54dfa5625a5bcab9011323c807ad3b64 537 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 231 443 1.5E-63 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS19680 54dfa5625a5bcab9011323c807ad3b64 537 SUPERFAMILY SSF111369 247 446 3.4E-10 T 06-07-2017 CAK95_RS19680 54dfa5625a5bcab9011323c807ad3b64 537 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 327 519 3.4E-36 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS19680 54dfa5625a5bcab9011323c807ad3b64 537 Gene3D G3DSA:2.40.50.100 327 367 8.4E-6 T 06-07-2017 CAK95_RS19680 54dfa5625a5bcab9011323c807ad3b64 537 Gene3D G3DSA:2.40.50.100 243 280 8.4E-6 T 06-07-2017 CAK95_RS01320 10d6edadbad6cd813ad6586e932227a9 383 Pfam PF01734 Patatin-like phospholipase 23 223 8.9E-30 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS01320 10d6edadbad6cd813ad6586e932227a9 383 Gene3D G3DSA:3.40.1090.10 12 224 2.8E-10 T 06-07-2017 CAK95_RS01320 10d6edadbad6cd813ad6586e932227a9 383 Pfam PF12536 Patatin phospholipase 261 365 3.4E-33 T 06-07-2017 IPR021095 Protein of unknown function DUF3734 CAK95_RS01320 10d6edadbad6cd813ad6586e932227a9 383 SUPERFAMILY SSF52151 19 93 1.92E-53 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS01320 10d6edadbad6cd813ad6586e932227a9 383 SUPERFAMILY SSF52151 131 356 1.92E-53 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS27225 4b150dff3e87d93f9bd695bf47cc759f 384 Gene3D G3DSA:2.60.120.10 53 198 3.8E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS27225 4b150dff3e87d93f9bd695bf47cc759f 384 Gene3D G3DSA:2.60.120.10 240 369 1.0E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS27225 4b150dff3e87d93f9bd695bf47cc759f 384 Pfam PF07883 Cupin domain 113 173 7.2E-14 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS27225 4b150dff3e87d93f9bd695bf47cc759f 384 SUPERFAMILY SSF51182 15 370 1.45E-74 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 14 696 0.0 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 312 318 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 78 344 2.0E-32 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 436 620 6.0E-44 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 15 699 41.512 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 492 1.4E-22 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 570 1.4E-22 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 1.4E-22 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 554 1.4E-22 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 1.4E-22 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF56784 357 409 8.0E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF56784 454 578 8.0E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF56784 298 322 8.0E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Pfam PF00702 haloacid dehalogenase-like hydrolase 306 549 1.9E-29 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Gene3D G3DSA:3.40.50.1000 462 582 3.9E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF81665 213 304 2.09E-11 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF81665 38 109 2.09E-11 T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 ProSitePatterns PS01229 Hypothetical cof family signature 2. 535 557 - T 06-07-2017 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Gene3D G3DSA:3.40.1110.10 321 461 7.8E-48 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Gene3D G3DSA:2.70.150.10 40 213 1.9E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 Pfam PF00122 E1-E2 ATPase 78 301 2.9E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK95_RS27595 7bdf2758f5d2fd7a27952a2709c3301d 701 SUPERFAMILY SSF81653 123 212 3.92E-21 T 06-07-2017 CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 SUPERFAMILY SSF51604 128 335 1.57E-54 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 SUPERFAMILY SSF54826 8 121 7.39E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 Gene3D G3DSA:3.30.390.10 7 111 9.9E-36 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 SMART SM00922 139 230 1.1E-20 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 Pfam PF13378 Enolase C-terminal domain-like 147 300 2.7E-28 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 Gene3D G3DSA:3.20.20.120 128 325 3.8E-59 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS17935 d7e2affa6f636d7cdc9da2b08ad157ca 335 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 121 1.3E-12 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAK95_RS27130 d208217eded0c9c389b28e06d25b627e 323 PIRSF PIRSF017082 1 323 2.8E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27130 d208217eded0c9c389b28e06d25b627e 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 3.6E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27130 d208217eded0c9c389b28e06d25b627e 323 SUPERFAMILY SSF53850 80 287 1.3E-13 T 06-07-2017 CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 279 1.3E-9 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 SMART SM01092 181 282 5.6E-5 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 SUPERFAMILY SSF55447 180 281 2.75E-12 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 SUPERFAMILY SSF56176 1 174 6.0E-47 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 Gene3D G3DSA:3.30.390.50 182 280 1.1E-15 T 06-07-2017 CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 Gene3D G3DSA:3.30.43.10 1 54 1.2E-17 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 Gene3D G3DSA:3.30.465.10 61 174 5.6E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS27530 149ea91e3bf3c6f3382f10b0878f88b6 288 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 8.2E-42 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS10115 2c5fd616162656b56fcbed2d4cd54143 246 Gene3D G3DSA:3.40.50.300 2 243 1.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10115 2c5fd616162656b56fcbed2d4cd54143 246 SUPERFAMILY SSF52540 3 244 1.04E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10115 2c5fd616162656b56fcbed2d4cd54143 246 Pfam PF00005 ABC transporter 21 175 1.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10115 2c5fd616162656b56fcbed2d4cd54143 246 SMART SM00382 29 222 7.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 SUPERFAMILY SSF81301 576 843 8.07E-67 T 06-07-2017 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 69 990 17.084 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Gene3D G3DSA:3.30.460.10 677 843 5.9E-46 T 06-07-2017 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Gene3D G3DSA:3.30.460.10 153 326 4.5E-49 T 06-07-2017 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 SUPERFAMILY SSF81301 50 327 1.7E-67 T 06-07-2017 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Pfam PF08335 GlnD PII-uridylyltransferase 863 994 8.0E-14 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Pfam PF08335 GlnD PII-uridylyltransferase 338 480 9.5E-40 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 595 834 9.7E-65 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 72 318 1.9E-64 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 SUPERFAMILY SSF81593 328 480 2.67E-40 T 06-07-2017 CAK95_RS19195 364001aa18a40d753959c419554d387d 1005 SUPERFAMILY SSF81593 852 995 1.18E-32 T 06-07-2017 CAK95_RS08530 4183ccc0c519e8c22c0e307058028fd6 168 Gene3D G3DSA:3.90.960.10 1 163 1.7E-56 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS08530 4183ccc0c519e8c22c0e307058028fd6 168 SUPERFAMILY SSF55826 3 162 6.8E-44 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS08530 4183ccc0c519e8c22c0e307058028fd6 168 Pfam PF04073 Aminoacyl-tRNA editing domain 24 149 1.8E-23 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 SUPERFAMILY SSF52374 5 284 1.53E-99 T 06-07-2017 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 80 1.5E-7 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 8 283 6.2E-90 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 Gene3D G3DSA:3.40.50.620 4 180 3.1E-70 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 Gene3D G3DSA:3.30.1300.10 181 283 1.2E-30 T 06-07-2017 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 Pfam PF02569 Pantoate-beta-alanine ligase 8 282 1.3E-95 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK95_RS21915 6db4a5e82e55b1635fd1f572a78c65aa 284 Hamap MF_00158 Pantothenate synthetase [panC]. 7 284 37.802 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 58 289 2.6E-60 T 06-07-2017 CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 SUPERFAMILY SSF51735 51 290 8.93E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 184 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 134 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 197 216 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 52 69 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 235 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 134 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 252 272 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 186 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 216 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 Gene3D G3DSA:3.40.50.720 41 298 8.4E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01075 fb3e93e6767a3e97bbaf9ec5bf14303b 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 184 212 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS01905 fb9b50a2d85109bc443cf68f970e9ea4 65 Gene3D G3DSA:3.10.20.30 1 65 1.6E-22 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS01905 fb9b50a2d85109bc443cf68f970e9ea4 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 1.7E-20 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis CAK95_RS01905 fb9b50a2d85109bc443cf68f970e9ea4 65 Pfam PF02597 ThiS family 4 65 1.5E-15 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAK95_RS01905 fb9b50a2d85109bc443cf68f970e9ea4 65 SUPERFAMILY SSF54285 2 64 4.94E-17 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 SMART SM00934 13 229 8.4E-76 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 228 1.4E-44 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 Gene3D G3DSA:3.20.20.70 11 233 1.3E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 65 78 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 14 229 5.0E-55 T 06-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 SUPERFAMILY SSF51366 9 236 3.46E-62 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS08935 5342f8aec1de91e278fee15da1fb46ec 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 11 234 34.158 T 06-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK95_RS15655 1032f429738bb1249f86c1eead6f6d6e 158 Pfam PF03061 Thioesterase superfamily 67 144 5.0E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS15655 1032f429738bb1249f86c1eead6f6d6e 158 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 36 152 1.4E-25 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS15655 1032f429738bb1249f86c1eead6f6d6e 158 Gene3D G3DSA:3.10.129.10 18 154 4.6E-52 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15655 1032f429738bb1249f86c1eead6f6d6e 158 SUPERFAMILY SSF54637 17 152 2.85E-35 T 06-07-2017 IPR029069 HotDog domain CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 Gene3D G3DSA:1.10.10.10 33 104 5.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 SMART SM00346 34 124 1.7E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 SUPERFAMILY SSF55781 100 275 7.85E-25 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 Pfam PF09339 IclR helix-turn-helix domain 36 86 1.1E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 Pfam PF01614 Bacterial transcriptional regulator 156 272 5.4E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 SUPERFAMILY SSF46785 34 108 1.98E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19325 c908f5003d69d10be45687021d5a3d19 279 Gene3D G3DSA:3.30.450.40 105 276 9.1E-26 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS27975 b4b94fa3a6bf0dc5caaa9241539bf250 210 SUPERFAMILY SSF53474 102 200 1.99E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27975 b4b94fa3a6bf0dc5caaa9241539bf250 210 SUPERFAMILY SSF53474 18 38 1.99E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27975 b4b94fa3a6bf0dc5caaa9241539bf250 210 Gene3D G3DSA:3.40.50.1820 136 193 1.3E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27975 b4b94fa3a6bf0dc5caaa9241539bf250 210 Gene3D G3DSA:3.40.50.1820 25 50 1.3E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27975 b4b94fa3a6bf0dc5caaa9241539bf250 210 Pfam PF03583 Secretory lipase 7 202 3.5E-14 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 424 9.5E-137 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 Gene3D G3DSA:3.90.1150.10 291 425 1.2E-50 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 424 2.9E-188 T 06-07-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 Gene3D G3DSA:3.40.640.10 7 289 1.1E-110 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 PIRSF PIRSF001434 1 426 2.6E-121 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 SUPERFAMILY SSF53383 7 425 1.2E-128 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS22635 e295ba643fd41b2301c01f25494bf7b2 426 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 SUPERFAMILY SSF75625 296 399 3.79E-10 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Gene3D G3DSA:3.20.70.20 43 65 1.8E-93 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Gene3D G3DSA:3.20.70.20 664 710 1.8E-93 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Gene3D G3DSA:3.20.70.20 390 591 1.8E-93 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Gene3D G3DSA:3.20.70.20 102 302 1.8E-93 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Gene3D G3DSA:3.20.70.20 872 918 1.8E-93 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 SUPERFAMILY SSF51998 841 925 4.58E-124 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 SUPERFAMILY SSF51998 197 302 4.58E-124 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 SUPERFAMILY SSF51998 394 716 4.58E-124 T 06-07-2017 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 PRINTS PR01183 Ribonucleotide reductase large chain signature 275 294 6.8E-5 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 565 6.8E-5 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 31 147 1.2E-41 T 06-07-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 129 755 5.5E-141 T 06-07-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Pfam PF02867 Ribonucleotide reductase, barrel domain 198 751 3.1E-105 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS25375 cbc953685d9a6f76ded2a5227ef77bff 1254 Pfam PF02867 Ribonucleotide reductase, barrel domain 809 913 2.2E-17 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK95_RS15780 5dfae31506cb42e0a32b4ed51f31c222 575 SUPERFAMILY SSF143975 5 377 9.42E-125 T 06-07-2017 CAK95_RS15780 5dfae31506cb42e0a32b4ed51f31c222 575 Pfam PF00920 Dehydratase family 43 558 9.7E-179 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS15780 5dfae31506cb42e0a32b4ed51f31c222 575 SUPERFAMILY SSF52016 380 564 3.77E-55 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS15780 5dfae31506cb42e0a32b4ed51f31c222 575 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 126 136 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS14240 93e48fe4f0b1417a2b4d4b8c05c0d155 182 Pfam PF02615 Malate/L-lactate dehydrogenase 24 109 1.1E-12 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS14240 93e48fe4f0b1417a2b4d4b8c05c0d155 182 SUPERFAMILY SSF89733 24 110 1.1E-12 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 SUPERFAMILY SSF69118 6 118 1.31E-20 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 Pfam PF02627 Carboxymuconolactone decarboxylase family 157 246 1.4E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 Pfam PF02627 Carboxymuconolactone decarboxylase family 32 104 4.5E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 SUPERFAMILY SSF69118 129 247 5.88E-23 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 Gene3D G3DSA:1.20.1290.10 118 250 3.3E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS12270 e84ef05903ab881b267ccaebbf40112b 254 Gene3D G3DSA:1.20.1290.10 7 117 1.5E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS28860 f70e4ed041ff75a8a48c5bdb5cab4f96 269 Gene3D G3DSA:1.10.3720.10 71 255 1.9E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28860 f70e4ed041ff75a8a48c5bdb5cab4f96 269 SUPERFAMILY SSF161098 71 249 2.35E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28860 f70e4ed041ff75a8a48c5bdb5cab4f96 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 254 4.8E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Gene3D G3DSA:3.20.20.60 5 75 2.3E-93 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Gene3D G3DSA:3.20.20.60 169 323 2.3E-93 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Gene3D G3DSA:2.40.33.10 76 167 9.2E-24 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 SUPERFAMILY SSF52935 320 471 3.92E-39 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 2.3E-32 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 SUPERFAMILY SSF51621 2 78 4.89E-93 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 SUPERFAMILY SSF51621 168 340 4.89E-93 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.9E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Gene3D G3DSA:3.40.1380.20 324 467 1.3E-44 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 SUPERFAMILY SSF50800 73 167 4.36E-23 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 468 1.3E-143 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS16550 9aae1dab5fa3cfaa769277b3c39c970b 477 Pfam PF00224 Pyruvate kinase, barrel domain 5 335 2.9E-109 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 Pfam PF13180 PDZ domain 261 339 7.3E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 SMART SM00228 261 332 1.3E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 PRINTS PR00834 HtrA/DegQ protease family signature 92 104 1.0E-11 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 1.0E-11 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 PRINTS PR00834 HtrA/DegQ protease family signature 289 301 1.0E-11 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 PRINTS PR00834 HtrA/DegQ protease family signature 113 133 1.0E-11 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 Gene3D G3DSA:2.40.10.10 80 152 2.7E-13 T 06-07-2017 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 Gene3D G3DSA:2.40.10.10 153 251 3.3E-9 T 06-07-2017 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 SUPERFAMILY SSF50494 49 253 5.52E-30 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 Gene3D G3DSA:2.30.42.10 252 340 3.0E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 SUPERFAMILY SSF50156 271 340 4.07E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS09540 6e7598ba9e3aa8faea969595cc9d691b 354 Pfam PF13365 Trypsin-like peptidase domain 83 216 1.7E-15 T 06-07-2017 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 Gene3D G3DSA:3.20.20.10 36 269 1.7E-81 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 1.2E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 300 318 1.2E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 1.2E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 383 405 1.2E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 SUPERFAMILY SSF50621 255 418 1.3E-49 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 416 39.385 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 287 392 3.0E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 Gene3D G3DSA:2.40.37.10 270 420 5.6E-43 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 SUPERFAMILY SSF51419 26 284 4.45E-80 T 06-07-2017 IPR029066 PLP-binding barrel CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 272 291 6.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 373 386 6.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 6.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 6.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 6.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 282 1.9E-59 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK95_RS12080 ffe0efb9a88bd7afd561715f1996e8e8 421 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 414 9.2E-144 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS27200 5005e276f66c550a15ce0b35bdd6c323 423 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 419 5.7E-120 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS27200 5005e276f66c550a15ce0b35bdd6c323 423 PIRSF PIRSF006066 1 423 3.7E-125 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS27200 5005e276f66c550a15ce0b35bdd6c323 423 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 415 9.8E-108 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 20 399 43.406 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Gene3D G3DSA:1.10.1740.10 317 399 1.8E-26 T 06-07-2017 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 19 396 2.0E-129 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 PIRSF PIRSF006205 17 405 2.1E-143 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 20 145 3.0E-36 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 159 242 2.5E-38 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Gene3D G3DSA:3.40.50.720 14 163 2.9E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 SUPERFAMILY SSF55347 139 277 3.27E-57 T 06-07-2017 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 SUPERFAMILY SSF51735 17 163 6.36E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 Pfam PF13288 DXP reductoisomerase C-terminal domain 274 394 5.2E-38 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS22985 17fe687ef7c559b4e0aeabc9ef8a537d 406 SUPERFAMILY SSF69055 304 399 4.71E-27 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 SUPERFAMILY SSF51905 271 357 3.82E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 SUPERFAMILY SSF51905 6 169 3.82E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.3E-22 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 4.3E-22 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 4.3E-22 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 4.3E-22 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 4.3E-22 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 SUPERFAMILY SSF54373 174 274 1.45E-13 T 06-07-2017 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 Gene3D G3DSA:3.50.50.60 6 175 2.6E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 Gene3D G3DSA:3.50.50.60 272 354 2.6E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14025 51d8a8cf8edc9bffcd9b7caceb25c2b0 385 Pfam PF01494 FAD binding domain 7 345 2.8E-26 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS16700 a15e05cefb2e60beabb7c5e242e36fcd 183 Pfam PF05751 FixH 30 177 3.4E-26 T 06-07-2017 IPR008620 Nitrogen fixation protein FixH CAK95_RS16700 a15e05cefb2e60beabb7c5e242e36fcd 183 PIRSF PIRSF011386 19 183 7.1E-36 T 06-07-2017 IPR018037 Nitrogen fixation protein FixH, Proteobacterial CAK95_RS08440 51c9cc6cde458578f66804a556a89121 236 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 233 5.1E-35 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08440 51c9cc6cde458578f66804a556a89121 236 SUPERFAMILY SSF69618 2 235 1.12E-42 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK95_RS08440 51c9cc6cde458578f66804a556a89121 236 Gene3D G3DSA:3.40.50.10090 138 235 5.3E-9 T 06-07-2017 CAK95_RS08440 51c9cc6cde458578f66804a556a89121 236 Gene3D G3DSA:3.40.50.10090 28 137 4.0E-20 T 06-07-2017 CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 13 352 7.9E-87 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 Pfam PF04055 Radical SAM superfamily 15 182 6.1E-20 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 Gene3D G3DSA:3.80.30.20 13 246 5.5E-31 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 SUPERFAMILY SSF102114 10 385 5.23E-105 T 06-07-2017 CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 Pfam PF06969 HemN C-terminal domain 313 375 1.6E-7 T 06-07-2017 IPR010723 HemN, C-terminal CAK95_RS08875 37abc3cf5846221686d9e1d09780befa 387 SMART SM00729 10 230 8.4E-46 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS28535 054fa0b7ed9842ca6c3063a22dedfa65 470 Gene3D G3DSA:3.30.70.1400 60 131 7.6E-12 T 06-07-2017 CAK95_RS28535 054fa0b7ed9842ca6c3063a22dedfa65 470 SUPERFAMILY SSF103025 18 259 3.45E-52 T 06-07-2017 CAK95_RS28535 054fa0b7ed9842ca6c3063a22dedfa65 470 SUPERFAMILY SSF103025 294 333 3.45E-52 T 06-07-2017 CAK95_RS28535 054fa0b7ed9842ca6c3063a22dedfa65 470 Pfam PF01571 Aminomethyltransferase folate-binding domain 35 258 9.7E-42 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK95_RS28535 054fa0b7ed9842ca6c3063a22dedfa65 470 Gene3D G3DSA:3.30.1360.120 164 255 8.3E-13 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS05650 3ff2ec1a37effd08fce76dc255693a68 348 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 6 332 9.7E-141 T 06-07-2017 IPR026360 Putative exonuclease, DNA ligase-associated CAK95_RS05650 3ff2ec1a37effd08fce76dc255693a68 348 SUPERFAMILY SSF56281 10 316 1.49E-60 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS05650 3ff2ec1a37effd08fce76dc255693a68 348 SMART SM00849 12 175 0.0045 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS05650 3ff2ec1a37effd08fce76dc255693a68 348 Gene3D G3DSA:3.60.15.10 27 153 4.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS25275 d4891cdc0f7bb954a41ca254536bc762 404 SUPERFAMILY SSF53822 30 390 2.41E-78 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS25275 d4891cdc0f7bb954a41ca254536bc762 404 Gene3D G3DSA:3.40.50.2300 154 307 1.0E-16 T 06-07-2017 CAK95_RS25275 d4891cdc0f7bb954a41ca254536bc762 404 Gene3D G3DSA:3.40.50.2300 308 358 1.6E-40 T 06-07-2017 CAK95_RS25275 d4891cdc0f7bb954a41ca254536bc762 404 Gene3D G3DSA:3.40.50.2300 25 153 1.6E-40 T 06-07-2017 CAK95_RS25275 d4891cdc0f7bb954a41ca254536bc762 404 Pfam PF13458 Periplasmic binding protein 41 368 1.4E-68 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS04630 1a61c197bb4e0e0c12b504862cb8d3f8 184 Pfam PF02600 Disulfide bond formation protein DsbB 19 168 1.1E-30 T 06-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CAK95_RS04630 1a61c197bb4e0e0c12b504862cb8d3f8 184 Gene3D G3DSA:1.20.1550.10 18 176 6.3E-18 T 06-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain CAK95_RS04630 1a61c197bb4e0e0c12b504862cb8d3f8 184 SUPERFAMILY SSF158442 23 168 2.09E-31 T 06-07-2017 CAK95_RS04630 1a61c197bb4e0e0c12b504862cb8d3f8 184 PIRSF PIRSF033913 8 175 1.2E-39 T 06-07-2017 IPR024199 Uncharacterised conserved protein, DsbB-like CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 SMART SM00116 74 122 1.7E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 SMART SM00116 10 57 2.1E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 SUPERFAMILY SSF54631 1 117 3.28E-33 T 06-07-2017 CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 Gene3D G3DSA:3.10.580.10 1 117 1.2E-33 T 06-07-2017 CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 Pfam PF00571 CBS domain 67 118 1.3E-10 T 06-07-2017 IPR000644 CBS domain CAK95_RS28300 290a8d5b06fc91d8e3aba06fa22a0d24 153 Pfam PF00571 CBS domain 3 53 1.7E-11 T 06-07-2017 IPR000644 CBS domain CAK95_RS07265 66a35afa79fc4b7da0d52ebf07331769 199 Gene3D G3DSA:3.40.630.30 5 164 4.4E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS07265 66a35afa79fc4b7da0d52ebf07331769 199 Pfam PF13302 Acetyltransferase (GNAT) domain 23 158 2.4E-29 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS07265 66a35afa79fc4b7da0d52ebf07331769 199 SUPERFAMILY SSF55729 16 162 8.47E-40 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 Gene3D G3DSA:3.40.190.10 46 169 1.7E-28 T 06-07-2017 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 SMART SM00079 46 366 3.1E-6 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 373 1.1E-42 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 Pfam PF00060 Ligand-gated ion channel 164 265 1.4E-16 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 Gene3D G3DSA:1.10.287.70 170 246 1.0E-12 T 06-07-2017 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 Gene3D G3DSA:3.40.190.10 252 337 1.0E-17 T 06-07-2017 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 SUPERFAMILY SSF81324 151 253 4.32E-13 T 06-07-2017 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 SMART SM00062 46 375 4.6E-13 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 SUPERFAMILY SSF53850 21 148 4.56E-49 T 06-07-2017 CAK95_RS19950 1f5729113246439b9e0719adb959f75e 375 SUPERFAMILY SSF53850 259 374 4.56E-49 T 06-07-2017 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 SUPERFAMILY SSF52768 2 307 4.65E-108 T 06-07-2017 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 Gene3D G3DSA:3.40.800.20 3 307 1.4E-107 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 Pfam PF00850 Histone deacetylase domain 20 306 5.7E-86 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 1.1E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 1.1E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAK95_RS15930 8cd9bda1a61d8aea789c6313e0e88f42 309 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 1.1E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 Gene3D G3DSA:3.10.290.10 97 194 2.4E-33 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 Gene3D G3DSA:1.10.1050.10 1 96 1.1E-31 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 Pfam PF01479 S4 domain 94 141 3.6E-20 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 93 1.3E-20 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 SMART SM00363 94 158 4.8E-20 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 SMART SM01390 3 93 9.2E-38 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 SUPERFAMILY SSF55174 6 205 1.83E-62 T 06-07-2017 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 92 116 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 205 9.0E-72 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS26465 3247beee74236c11d0df07c1812778ef 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 205 32.087 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 PIRSF PIRSF000429 1 402 1.3E-110 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Pfam PF00108 Thiolase, N-terminal domain 5 231 4.8E-41 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Gene3D G3DSA:3.40.47.10 143 184 3.6E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Gene3D G3DSA:3.40.47.10 286 401 3.6E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 SUPERFAMILY SSF53901 3 279 2.39E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 SUPERFAMILY SSF53901 280 401 1.62E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Gene3D G3DSA:3.40.47.10 3 126 2.0E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Gene3D G3DSA:3.40.47.10 185 285 2.0E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 1.8E-122 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS11510 7561a00908254d74f9c029863e9f551d 402 Pfam PF02803 Thiolase, C-terminal domain 279 401 3.0E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 Gene3D G3DSA:1.20.1560.10 22 340 1.1E-9 T 06-07-2017 CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 Pfam PF00005 ABC transporter 389 520 9.1E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 Pfam PF06472 ABC transporter transmembrane region 2 5 296 5.1E-73 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 SMART SM00382 394 567 1.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 SUPERFAMILY SSF52540 365 566 6.66E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 Gene3D G3DSA:3.40.50.300 369 562 1.1E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13080 0027b07d95623d1fcc18afae01adfd1e 581 SUPERFAMILY SSF90123 28 341 3.27E-22 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 Gene3D G3DSA:3.40.50.720 2 249 1.9E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 3.0E-58 T 06-07-2017 CAK95_RS00895 3fc8153eb066f3b514bdb251c13820fa 255 SUPERFAMILY SSF51735 4 249 7.65E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Gene3D G3DSA:3.40.1190.10 97 318 8.7E-65 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Pfam PF01225 Mur ligase family, catalytic domain 29 101 2.2E-10 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 464 4.5E-115 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 SUPERFAMILY SSF53244 329 464 2.81E-32 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 SUPERFAMILY SSF63418 24 103 1.57E-19 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 338 407 1.2E-9 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 7 465 31.789 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Gene3D G3DSA:3.90.190.20 329 467 1.9E-36 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Gene3D G3DSA:3.40.1390.10 25 96 1.4E-20 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 SUPERFAMILY SSF53623 109 321 4.71E-51 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14490 29f78abeb2e69eca9bc35b88b974213a 481 Pfam PF08245 Mur ligase middle domain 113 303 3.5E-45 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK95_RS14065 2e9997fcf4deab482dd1692986c8600e 97 Gene3D G3DSA:3.30.70.900 1 96 1.9E-25 T 06-07-2017 CAK95_RS14065 2e9997fcf4deab482dd1692986c8600e 97 Pfam PF07045 Domain of unknown function (DUF1330) 3 95 4.9E-22 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 CAK95_RS14065 2e9997fcf4deab482dd1692986c8600e 97 SUPERFAMILY SSF54909 1 94 1.3E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS10895 b6192b8b944325f416dc2de0802b8100 437 Pfam PF13416 Bacterial extracellular solute-binding protein 44 355 7.1E-31 T 06-07-2017 CAK95_RS10895 b6192b8b944325f416dc2de0802b8100 437 SUPERFAMILY SSF53850 25 424 1.25E-62 T 06-07-2017 CAK95_RS10895 b6192b8b944325f416dc2de0802b8100 437 Gene3D G3DSA:3.40.190.10 145 356 7.2E-31 T 06-07-2017 CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 1.5E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.5E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 1.5E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 SUPERFAMILY SSF46785 7 146 1.29E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 Gene3D G3DSA:1.10.10.10 3 145 2.8E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 SMART SM00347 32 132 2.8E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS20265 4844f89a8486214231797f6f5aae9134 153 Pfam PF12802 MarR family 38 96 1.1E-14 T 06-07-2017 CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 1 401 1.8E-206 T 06-07-2017 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 SUPERFAMILY SSF53383 2 398 2.66E-117 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 Gene3D G3DSA:3.40.640.10 64 280 1.1E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 Gene3D G3DSA:3.90.1150.10 281 396 5.7E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 Pfam PF00155 Aminotransferase class I and II 46 390 8.7E-78 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS05370 e0ee3e139b6197d3076ef5f1cdd6adc4 408 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 244 253 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Pfam PF00580 UvrD/REP helicase N-terminal domain 35 478 8.1E-49 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:3.40.50.300 774 911 3.1E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:3.40.50.300 496 622 3.1E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 SUPERFAMILY SSF52540 852 882 7.51E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 SUPERFAMILY SSF52540 128 226 7.51E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 SUPERFAMILY SSF52540 358 810 7.51E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 SUPERFAMILY SSF52540 39 90 7.51E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:3.40.50.300 136 198 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:3.40.50.300 32 86 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:3.40.50.300 368 480 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Pfam PF13361 UvrD-like helicase C-terminal domain 738 873 1.7E-14 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 SUPERFAMILY SSF52980 980 1122 8.58E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Gene3D G3DSA:1.10.486.10 635 764 1.5E-9 T 06-07-2017 CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 26 1141 0.0 T 06-07-2017 IPR014151 DNA helicase, AddA type CAK95_RS11010 e4ab456dc804426adea30f083dca1a31 1156 Pfam PF12705 PD-(D/E)XK nuclease superfamily 983 1131 1.5E-8 T 06-07-2017 CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 15 866 0.0 T 06-07-2017 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 Pfam PF03176 MMPL family 238 434 7.4E-25 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 SUPERFAMILY SSF82866 667 862 3.92E-22 T 06-07-2017 CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 Gene3D G3DSA:1.20.1640.10 716 862 7.5E-15 T 06-07-2017 CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 Gene3D G3DSA:1.20.1640.10 241 441 2.8E-32 T 06-07-2017 CAK95_RS04520 4bd66ebbca09af2aeaebe7e54b7286b1 877 SUPERFAMILY SSF82866 243 437 3.14E-29 T 06-07-2017 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 Gene3D G3DSA:3.40.50.1440 16 217 6.8E-95 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 177 2.2E-43 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 SMART SM00864 16 208 7.4E-113 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 SMART SM00865 210 328 6.8E-56 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 Pfam PF12327 FtsZ family, C-terminal domain 225 320 1.6E-35 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 PRINTS PR00423 Cell division protein FtsZ signature 192 214 1.6E-48 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 PRINTS PR00423 Cell division protein FtsZ signature 215 236 1.6E-48 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 PRINTS PR00423 Cell division protein FtsZ signature 101 121 1.6E-48 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 PRINTS PR00423 Cell division protein FtsZ signature 129 150 1.6E-48 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 SUPERFAMILY SSF52490 15 211 1.83E-70 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 12 351 37.598 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 ProSitePatterns PS01135 FtsZ protein signature 2. 100 121 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 14 331 1.1E-123 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 SUPERFAMILY SSF55307 210 322 4.58E-41 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 ProSitePatterns PS01134 FtsZ protein signature 1. 47 81 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 TIGRFAM TIGR03483 FtsZ_alphas_C: cell division protein FtsZ, alphaProteobacterial C-terminal extension 437 573 5.5E-26 T 06-07-2017 IPR017844 Cell division protein FtsZ, C-terminal extension GO:0000910|GO:0005525|GO:0005737 CAK95_RS01755 ee75dfd742232a78fe40cc96f44e50a1 573 Gene3D G3DSA:3.30.1330.20 218 322 8.3E-48 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 Gene3D G3DSA:2.60.120.460 17 152 5.1E-53 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 PIRSF PIRSF004681 15 153 1.9E-50 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 114 132 - T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 Pfam PF01894 Uncharacterised protein family UPF0047 34 149 9.3E-39 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 SUPERFAMILY SSF111038 19 152 2.88E-47 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS05560 9c0dab9078b2fe2d0f82203a057eee3e 156 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 27 152 4.0E-40 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 Pfam PF04773 FecR protein 147 244 6.1E-12 T 06-07-2017 IPR006860 FecR protein CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 SUPERFAMILY SSF49313 754 872 6.57E-7 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 SUPERFAMILY SSF51120 1002 1079 1.7E-8 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 576 635 1.3E-5 T 06-07-2017 IPR010221 VCBS repeat CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 684 772 3.7E-14 T 06-07-2017 IPR010221 VCBS repeat CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 459 535 1.6E-5 T 06-07-2017 IPR010221 VCBS repeat CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 809 877 5.1E-15 T 06-07-2017 IPR010221 VCBS repeat CAK95_RS09850 fb9b73a24a7411e33a7222e12e1e17cb 1121 Gene3D G3DSA:2.60.40.60 754 875 1.7E-5 T 06-07-2017 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 SUPERFAMILY SSF46785 9 68 7.87E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 Pfam PF01037 Lrp/AsnC ligand binding domain 75 149 5.8E-22 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 Gene3D G3DSA:3.30.70.920 62 157 6.4E-30 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 SUPERFAMILY SSF54909 71 157 3.08E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 56 5.5E-18 T 06-07-2017 CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 SMART SM00344 9 118 7.6E-42 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 Gene3D G3DSA:1.10.10.10 8 60 7.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06870 8a7c4e2afe0172490d0f6cbcccc4b3c3 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 10 500 3.6E-142 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 Gene3D G3DSA:3.20.20.240 8 496 6.9E-177 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 Gene3D G3DSA:3.40.50.280 510 658 1.9E-49 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 530 659 7.3E-36 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 SUPERFAMILY SSF52242 508 659 1.96E-47 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 SUPERFAMILY SSF51703 9 496 1.52E-160 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 Pfam PF02310 B12 binding domain 533 634 1.5E-16 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS11875 3a90ad18f3a47881e38ace464215c930 663 Pfam PF01642 Methylmalonyl-CoA mutase 8 494 6.5E-132 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS05760 b32676d7dc766d55d58867fb751634cd 235 Gene3D G3DSA:1.10.357.10 17 196 1.4E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS05760 b32676d7dc766d55d58867fb751634cd 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 1.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05760 b32676d7dc766d55d58867fb751634cd 235 SUPERFAMILY SSF46689 20 86 7.98E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05760 b32676d7dc766d55d58867fb751634cd 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05760 b32676d7dc766d55d58867fb751634cd 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 SUPERFAMILY SSF51735 8 273 1.22E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 Gene3D G3DSA:3.40.50.720 13 259 1.7E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 Pfam PF00106 short chain dehydrogenase 16 217 2.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15025 3ec724f09b16dd2fd6ecb43a5ffa30ed 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 Gene3D G3DSA:2.30.130.10 265 324 2.0E-4 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 50 198 4.5E-52 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 28 323 18.757 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 SUPERFAMILY SSF55120 28 243 1.76E-78 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 29 237 8.6E-70 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 199 262 6.4E-16 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CAK95_RS09155 4f491c7ca12df5ddf975c9e5cc460122 338 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 266 323 1.3E-5 T 06-07-2017 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 86 269 1.8E-54 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 Gene3D G3DSA:1.20.1640.10 92 286 1.5E-28 T 06-07-2017 CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 PRINTS PR01755 Bacterial translocase SecF protein signature 25 40 1.1E-30 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 PRINTS PR01755 Bacterial translocase SecF protein signature 139 153 1.1E-30 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 PRINTS PR01755 Bacterial translocase SecF protein signature 187 205 1.1E-30 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 PRINTS PR01755 Bacterial translocase SecF protein signature 219 234 1.1E-30 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 26 272 7.2E-77 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 Pfam PF07549 SecD/SecF GG Motif 21 44 1.1E-7 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 1 283 27.37 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 Pfam PF02355 Protein export membrane protein 99 280 3.0E-64 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAK95_RS23865 042b927fafe924f79aafc753d099417d 323 SUPERFAMILY SSF82866 63 280 1.07E-38 T 06-07-2017 CAK95_RS00210 0b704f5aea249e40401cf9b1888a7278 457 Pfam PF16980 Putative citrate transport 16 456 6.9E-188 T 06-07-2017 IPR031566 Putative citrate transporter CAK95_RS00210 0b704f5aea249e40401cf9b1888a7278 457 PRINTS PR00758 Arsenical pump membrane protein signature 432 456 2.5E-5 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAK95_RS00210 0b704f5aea249e40401cf9b1888a7278 457 PRINTS PR00758 Arsenical pump membrane protein signature 119 143 2.5E-5 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAK95_RS00210 0b704f5aea249e40401cf9b1888a7278 457 PRINTS PR00758 Arsenical pump membrane protein signature 355 377 2.5E-5 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAK95_RS02265 a14212f012c6ec0d00b15049b566889f 444 Pfam PF00355 Rieske [2Fe-2S] domain 26 108 1.7E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02265 a14212f012c6ec0d00b15049b566889f 444 Gene3D G3DSA:2.102.10.10 24 139 4.9E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02265 a14212f012c6ec0d00b15049b566889f 444 SUPERFAMILY SSF55961 128 303 1.74E-36 T 06-07-2017 CAK95_RS02265 a14212f012c6ec0d00b15049b566889f 444 SUPERFAMILY SSF55961 333 415 1.74E-36 T 06-07-2017 CAK95_RS02265 a14212f012c6ec0d00b15049b566889f 444 SUPERFAMILY SSF50022 19 137 6.02E-33 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS14645 4c7c22d5b82dc2730d16a305c9baa176 70 SUPERFAMILY SSF46689 3 58 5.55E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14645 4c7c22d5b82dc2730d16a305c9baa176 70 Pfam PF04255 Protein of unknown function (DUF433) 6 59 3.6E-19 T 06-07-2017 IPR007367 Protein of unknown function DUF433 CAK95_RS14645 4c7c22d5b82dc2730d16a305c9baa176 70 Gene3D G3DSA:1.10.10.10 6 63 2.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 Gene3D G3DSA:3.40.50.720 2 227 6.8E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 Pfam PF00106 short chain dehydrogenase 6 195 1.9E-53 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 SUPERFAMILY SSF51735 1 229 1.82E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS16270 c3026d740fe6b184634a21c1a29e0648 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 4.4E-4 T 06-07-2017 CAK95_RS00195 ce8148652043136fbfa9c368d3e950b3 290 Gene3D G3DSA:3.90.850.10 71 289 1.3E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00195 ce8148652043136fbfa9c368d3e950b3 290 SUPERFAMILY SSF56529 68 286 2.62E-72 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00195 ce8148652043136fbfa9c368d3e950b3 290 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 284 1.2E-60 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS28545 4b3b22501c995ecb020e49ecc7a4ee54 54 SUPERFAMILY SSF53213 2 48 7.06E-8 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS28545 4b3b22501c995ecb020e49ecc7a4ee54 54 Gene3D G3DSA:3.40.830.10 2 49 4.1E-10 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS03210 94b4fd529fef88c4c3dffb83833cea4f 1272 Pfam PF13550 Putative phage tail protein 757 921 1.3E-41 T 06-07-2017 IPR032876 Tip attachment protein J CAK95_RS03210 94b4fd529fef88c4c3dffb83833cea4f 1272 Pfam PF13547 GTA TIM-barrel-like domain 416 696 1.3E-103 T 06-07-2017 IPR025195 GTA TIM-barrel-like domain CAK95_RS03210 94b4fd529fef88c4c3dffb83833cea4f 1272 SUPERFAMILY SSF51445 353 521 3.17E-11 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS03210 94b4fd529fef88c4c3dffb83833cea4f 1272 SUPERFAMILY SSF51445 655 688 3.17E-11 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS03210 94b4fd529fef88c4c3dffb83833cea4f 1272 SUPERFAMILY SSF51445 580 623 3.17E-11 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 110 124 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 SUPERFAMILY SSF55120 70 235 1.35E-36 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 Pfam PF00849 RNA pseudouridylate synthase 73 158 4.5E-9 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 Gene3D G3DSA:3.10.290.10 10 73 1.8E-23 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 SUPERFAMILY SSF55174 8 76 3.73E-15 T 06-07-2017 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 77 234 2.2E-37 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 SMART SM00363 12 71 1.7E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS13355 ea8b901b93a9b5f4e766dbe49cad08db 365 Pfam PF01479 S4 domain 13 58 9.0E-14 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS27670 34600ddc9eaa0d8a92091b4094e31fa1 397 SUPERFAMILY SSF111369 62 309 9.68E-62 T 06-07-2017 CAK95_RS27670 34600ddc9eaa0d8a92091b4094e31fa1 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 304 3.4E-13 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS27670 34600ddc9eaa0d8a92091b4094e31fa1 397 Gene3D G3DSA:2.40.50.100 73 107 6.1E-21 T 06-07-2017 CAK95_RS27670 34600ddc9eaa0d8a92091b4094e31fa1 397 Gene3D G3DSA:2.40.50.100 182 214 6.1E-21 T 06-07-2017 CAK95_RS27670 34600ddc9eaa0d8a92091b4094e31fa1 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 385 3.3E-83 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS02125 08341c530db0028c297254fd9623d550 206 Gene3D G3DSA:3.40.50.360 13 203 9.3E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS02125 08341c530db0028c297254fd9623d550 206 SUPERFAMILY SSF52218 21 197 9.83E-32 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS02125 08341c530db0028c297254fd9623d550 206 Pfam PF03358 NADPH-dependent FMN reductase 21 163 5.0E-22 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS04570 b6c5a5604fab279a82cc7a30b2cc20f6 196 Gene3D G3DSA:3.40.50.1820 40 172 1.2E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS04570 b6c5a5604fab279a82cc7a30b2cc20f6 196 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 40 55 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK95_RS04570 b6c5a5604fab279a82cc7a30b2cc20f6 196 SUPERFAMILY SSF53474 39 178 1.14E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13670 f394cebcd34ad212baec2cbe67eae3dd 317 SUPERFAMILY SSF161098 96 299 4.41E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS13670 f394cebcd34ad212baec2cbe67eae3dd 317 Gene3D G3DSA:1.10.3720.10 93 310 3.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS13670 f394cebcd34ad212baec2cbe67eae3dd 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 316 1.6E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 1.8E-12 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 1.8E-12 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 1.8E-12 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 255 273 1.8E-12 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 Pfam PF13458 Periplasmic binding protein 25 363 3.0E-78 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 Gene3D G3DSA:3.40.50.2300 148 288 1.7E-8 T 06-07-2017 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 SUPERFAMILY SSF53822 24 368 1.71E-97 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 Gene3D G3DSA:3.40.50.2300 20 147 1.4E-57 T 06-07-2017 CAK95_RS12355 16370a37b0bef6fbdaf5f1cfbbf17550 377 Gene3D G3DSA:3.40.50.2300 289 350 1.4E-57 T 06-07-2017 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 SUPERFAMILY SSF51735 2 164 3.94E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 287 2.6E-35 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 Gene3D G3DSA:3.40.50.720 1 164 6.8E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 PIRSF PIRSF000103 1 289 8.4E-68 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 8.2E-44 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 SUPERFAMILY SSF48179 166 289 8.62E-40 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS19820 af955e0eeaaeff9decb47998e8c9438c 289 Gene3D G3DSA:1.10.1040.10 166 289 1.9E-40 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-41 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 SUPERFAMILY SSF54111 1 100 1.11E-44 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 Gene3D G3DSA:3.30.280.10 1 100 3.0E-49 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 Pfam PF00547 Urease, gamma subunit 1 99 3.5E-47 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 PIRSF PIRSF001223 1 100 2.2E-50 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 3.6E-47 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17320 3933982eec77c4b18f8866ba6684b595 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.99 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS26745 eb7775659dcf4b145e7afc239a69377d 472 Gene3D G3DSA:1.20.1250.20 259 453 9.7E-13 T 06-07-2017 CAK95_RS26745 eb7775659dcf4b145e7afc239a69377d 472 Gene3D G3DSA:1.20.1250.20 31 212 4.3E-29 T 06-07-2017 CAK95_RS26745 eb7775659dcf4b145e7afc239a69377d 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK95_RS26745 eb7775659dcf4b145e7afc239a69377d 472 Pfam PF00083 Sugar (and other) transporter 61 452 8.4E-44 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK95_RS26745 eb7775659dcf4b145e7afc239a69377d 472 SUPERFAMILY SSF103473 16 458 8.37E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS17535 4fbda37e82c7edfca0efdae2a4716c95 82 SMART SM00530 14 69 6.4E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS17535 4fbda37e82c7edfca0efdae2a4716c95 82 Pfam PF01381 Helix-turn-helix 15 66 6.7E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS17535 4fbda37e82c7edfca0efdae2a4716c95 82 SUPERFAMILY SSF47413 4 75 9.65E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS17535 4fbda37e82c7edfca0efdae2a4716c95 82 Gene3D G3DSA:1.10.260.40 8 68 1.5E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 SUPERFAMILY SSF47741 85 158 1.3E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 Gene3D G3DSA:3.10.20.30 1 74 7.8E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 SUPERFAMILY SSF54292 1 78 3.01E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 Pfam PF01799 [2Fe-2S] binding domain 73 146 1.6E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 Gene3D G3DSA:1.10.150.120 75 171 4.1E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS28895 1a231fedfa85e0e249e20a73e5d13a86 199 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 57 4.6E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 SUPERFAMILY SSF46785 1 87 3.77E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 Gene3D G3DSA:3.40.190.10 88 182 2.5E-13 T 06-07-2017 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 SUPERFAMILY SSF53850 88 288 2.33E-28 T 06-07-2017 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 Gene3D G3DSA:3.40.190.10 183 247 2.0E-10 T 06-07-2017 CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 Pfam PF03466 LysR substrate binding domain 87 288 8.5E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 Gene3D G3DSA:1.10.10.10 1 85 4.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01345 ec596a2a54f5509e89509c107f81ec57 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS17595 1154be37b01f17409cfcf482b868c3ac 347 Gene3D G3DSA:3.40.50.2000 16 160 2.3E-35 T 06-07-2017 CAK95_RS17595 1154be37b01f17409cfcf482b868c3ac 347 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 16 318 1.5E-77 T 06-07-2017 IPR011910 Lipopolysaccharide heptosyltransferase II GO:0009103|GO:0016757 CAK95_RS17595 1154be37b01f17409cfcf482b868c3ac 347 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 84 306 2.9E-45 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAK95_RS17595 1154be37b01f17409cfcf482b868c3ac 347 Gene3D G3DSA:3.40.50.2000 175 336 4.4E-44 T 06-07-2017 CAK95_RS17595 1154be37b01f17409cfcf482b868c3ac 347 SUPERFAMILY SSF53756 16 336 5.02E-79 T 06-07-2017 CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 Gene3D G3DSA:1.20.1050.10 91 214 1.9E-38 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 SUPERFAMILY SSF52833 1 91 4.49E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 Gene3D G3DSA:3.40.30.10 1 90 1.7E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 Pfam PF14497 Glutathione S-transferase, C-terminal domain 126 202 4.6E-5 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 75 8.4E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 SUPERFAMILY SSF47616 82 213 2.84E-24 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS10145 fa2fee8ca68935c60fc8c468d15a8033 217 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 3 212 2.0E-68 T 06-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CAK95_RS03585 6bee2752fb620c7302c4ac75149162c7 590 SUPERFAMILY SSF52540 109 213 3.55E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03585 6bee2752fb620c7302c4ac75149162c7 590 SUPERFAMILY SSF52540 298 545 3.55E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03585 6bee2752fb620c7302c4ac75149162c7 590 Gene3D G3DSA:3.40.50.300 137 207 3.4E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03585 6bee2752fb620c7302c4ac75149162c7 590 Gene3D G3DSA:3.40.50.300 368 542 3.4E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03585 6bee2752fb620c7302c4ac75149162c7 590 Pfam PF01935 Domain of unknown function DUF87 119 408 1.6E-39 T 06-07-2017 IPR002789 Helicase HerA, central domain CAK95_RS26130 f6890f712c34920e8a75aec380e6424d 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 315 6.5E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26130 f6890f712c34920e8a75aec380e6424d 320 PIRSF PIRSF017082 1 319 1.7E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26130 f6890f712c34920e8a75aec380e6424d 320 Gene3D G3DSA:3.40.190.10 125 226 1.0E-4 T 06-07-2017 CAK95_RS26130 f6890f712c34920e8a75aec380e6424d 320 SUPERFAMILY SSF53850 108 280 1.97E-13 T 06-07-2017 CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 SUPERFAMILY SSF53098 1 169 2.16E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 Gene3D G3DSA:3.30.420.10 1 172 2.0E-58 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 225 2.5E-78 T 06-07-2017 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 Pfam PF00929 Exonuclease 4 163 7.1E-33 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 SMART SM00479 2 172 2.8E-37 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK95_RS08055 96f2e384c1879b429162977d8fbf80f8 231 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 171 1.0E-43 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 94 129 3.7E-12 T 06-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 17 126 6.7E-47 T 06-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 SUPERFAMILY SSF109635 4 95 2.48E-34 T 06-07-2017 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 SUPERFAMILY SSF57716 96 135 2.85E-9 T 06-07-2017 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 13 135 29.52 T 06-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CAK95_RS18180 2e86b99e1c2e09dfc45ed6cd37050120 137 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 99 123 - T 06-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CAK95_RS26915 52bdc90d99e8e27e8f889afd76267e01 406 SUPERFAMILY SSF48230 276 368 6.41E-14 T 06-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CAK95_RS26915 52bdc90d99e8e27e8f889afd76267e01 406 SUPERFAMILY SSF48230 76 235 6.41E-14 T 06-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CAK95_RS26915 52bdc90d99e8e27e8f889afd76267e01 406 Pfam PF05426 Alginate lyase 125 323 1.1E-11 T 06-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 CAK95_RS26915 52bdc90d99e8e27e8f889afd76267e01 406 Gene3D G3DSA:1.50.10.110 102 373 3.5E-19 T 06-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 CAK95_RS28335 e7ee649d95a3dea2bbb076e827536651 279 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 72 270 3.1E-67 T 06-07-2017 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CAK95_RS28335 e7ee649d95a3dea2bbb076e827536651 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 264 3.8E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28335 e7ee649d95a3dea2bbb076e827536651 279 Gene3D G3DSA:1.10.3720.10 81 265 4.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28335 e7ee649d95a3dea2bbb076e827536651 279 SUPERFAMILY SSF161098 86 267 3.01E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07900 69469ebecc85bb50e59f337f888274cb 273 Gene3D G3DSA:3.40.50.850 45 258 6.1E-58 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS07900 69469ebecc85bb50e59f337f888274cb 273 SUPERFAMILY SSF52499 45 256 4.58E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS07900 69469ebecc85bb50e59f337f888274cb 273 Pfam PF00857 Isochorismatase family 53 250 1.9E-39 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 SUPERFAMILY SSF56762 18 396 3.4E-137 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 8 396 4.8E-179 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 45 56 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 396 2.4E-122 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 Gene3D G3DSA:1.10.645.10 6 388 7.0E-66 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22845 c531dfafaa36613010207ade3a01b41e 396 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 396 48.704 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 SUPERFAMILY SSF51735 107 287 5.32E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 SUPERFAMILY SSF52283 3 127 8.08E-24 T 06-07-2017 CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 Gene3D G3DSA:3.40.50.720 115 288 5.5E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 287 2.1E-58 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 Gene3D G3DSA:3.40.50.720 3 114 1.9E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00655 04e8ca07ade8715d063d9942e61c2d17 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 313 1.4E-10 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 614 4.5E-246 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 SMART SM01228 539 610 8.3E-36 T 06-07-2017 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.2E-7 T 06-07-2017 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 468 488 7.2E-7 T 06-07-2017 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 617 41.265 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 SUPERFAMILY SSF51905 4 64 2.62E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 SUPERFAMILY SSF51905 95 258 2.62E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 270 284 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 Gene3D G3DSA:3.50.50.60 5 219 2.3E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 Pfam PF01134 Glucose inhibited division protein A 6 393 1.7E-165 T 06-07-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CAK95_RS08140 7b2a93f9ead65a6e49e2b5ecbb5f7d98 622 Pfam PF13932 GidA associated domain 399 608 2.3E-64 T 06-07-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CAK95_RS23080 b1ac4168cac9e373b9c993f142f97878 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 260 2.5E-95 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAK95_RS23080 b1ac4168cac9e373b9c993f142f97878 269 SUPERFAMILY SSF51366 12 262 1.01E-88 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS23080 b1ac4168cac9e373b9c993f142f97878 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CAK95_RS23080 b1ac4168cac9e373b9c993f142f97878 269 Gene3D G3DSA:3.20.20.70 1 262 4.8E-101 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS23080 b1ac4168cac9e373b9c993f142f97878 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 36.182 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 Gene3D G3DSA:3.40.190.10 221 257 1.2E-17 T 06-07-2017 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 Gene3D G3DSA:3.40.190.10 30 113 1.2E-17 T 06-07-2017 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 PIRSF PIRSF004846 1 260 1.1E-68 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 Pfam PF13531 Bacterial extracellular solute-binding protein 33 257 2.0E-45 T 06-07-2017 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 SUPERFAMILY SSF53850 31 257 1.38E-64 T 06-07-2017 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 Gene3D G3DSA:3.40.190.10 114 220 3.0E-38 T 06-07-2017 CAK95_RS06975 fbef2c2d908c1882ff9c78a4a9c73f59 265 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 38 256 5.1E-59 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 Gene3D G3DSA:3.20.20.70 25 156 2.6E-87 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 Gene3D G3DSA:3.20.20.70 192 456 2.6E-87 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 28 115 4.8E-8 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 214 319 1.1E-19 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 SUPERFAMILY SSF51395 354 451 2.32E-65 T 06-07-2017 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 SUPERFAMILY SSF51395 160 327 2.32E-65 T 06-07-2017 CAK95_RS17110 a2ed46a2a1e5beccc5150ffee429d935 483 SUPERFAMILY SSF51395 26 132 2.32E-65 T 06-07-2017 CAK95_RS16775 304bf9c771b0b9b1cd9365f6bc29d2c1 615 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 45 86 2.9E-19 T 06-07-2017 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal CAK95_RS16775 304bf9c771b0b9b1cd9365f6bc29d2c1 615 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 124 292 3.4E-57 T 06-07-2017 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 CAK95_RS16775 304bf9c771b0b9b1cd9365f6bc29d2c1 615 SUPERFAMILY SSF53474 247 534 1.08E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16775 304bf9c771b0b9b1cd9365f6bc29d2c1 615 Gene3D G3DSA:3.40.50.1820 247 581 3.0E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 Pfam PF00190 Cupin 281 394 4.7E-22 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 Pfam PF00190 Cupin 104 234 2.4E-24 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 87 422 1.2E-122 T 06-07-2017 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 SUPERFAMILY SSF51182 82 420 1.02E-85 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 Gene3D G3DSA:2.60.120.10 259 421 4.1E-53 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 Gene3D G3DSA:2.60.120.10 103 256 4.4E-51 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 SMART SM00835 95 239 7.9E-21 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS20945 50011a8e59f5bd79958933d3ae342e04 427 SMART SM00835 275 416 1.2E-29 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 SMART SM00493 83 168 8.5E-4 T 06-07-2017 IPR006171 Toprim domain CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 SUPERFAMILY SSF111304 8 201 7.06E-70 T 06-07-2017 IPR023627 Recombination protein RecR CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 Hamap MF_00017 Recombination protein RecR [recR]. 1 201 92.958 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 Pfam PF02132 RecR protein 44 81 1.1E-12 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 TIGRFAM TIGR00615 recR: recombination protein RecR 8 198 2.8E-65 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 ProSitePatterns PS01300 RecR protein signature. 60 81 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CAK95_RS02870 6b31f81fa8bac3ac8fdeb147a856c176 201 Pfam PF13662 Toprim domain 83 174 9.7E-24 T 06-07-2017 IPR006171 Toprim domain CAK95_RS10265 7bcbfababa634f0918a97b381afec10e 355 Pfam PF01734 Patatin-like phospholipase 27 220 1.0E-18 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS10265 7bcbfababa634f0918a97b381afec10e 355 Gene3D G3DSA:3.40.1090.10 20 223 4.7E-10 T 06-07-2017 CAK95_RS10265 7bcbfababa634f0918a97b381afec10e 355 SUPERFAMILY SSF52151 22 101 9.42E-48 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS10265 7bcbfababa634f0918a97b381afec10e 355 SUPERFAMILY SSF52151 132 345 9.42E-48 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 Gene3D G3DSA:1.20.1050.10 82 204 1.3E-22 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 SUPERFAMILY SSF52833 1 80 4.35E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 SUPERFAMILY SSF47616 76 208 2.05E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 Pfam PF02798 Glutathione S-transferase, N-terminal domain 8 79 5.8E-7 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 Gene3D G3DSA:3.40.30.10 4 81 1.7E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS20095 2dc030e33c4205d36522ea8f38f66d08 214 Pfam PF00043 Glutathione S-transferase, C-terminal domain 132 198 3.2E-8 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS27575 1e3ed5a1a2b5d874eb0aeca806a904eb 149 SUPERFAMILY SSF55804 1 144 2.49E-32 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CAK95_RS27575 1e3ed5a1a2b5d874eb0aeca806a904eb 149 Gene3D G3DSA:3.40.930.10 1 144 2.2E-36 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAK95_RS27575 1e3ed5a1a2b5d874eb0aeca806a904eb 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 144 1.2E-30 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAK95_RS16365 2b86cf09e1dce03e971fb0573c1ce545 197 Gene3D G3DSA:2.40.440.10 61 195 1.7E-34 T 06-07-2017 CAK95_RS16365 2b86cf09e1dce03e971fb0573c1ce545 197 Pfam PF03734 L,D-transpeptidase catalytic domain 67 194 8.1E-16 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS16365 2b86cf09e1dce03e971fb0573c1ce545 197 SUPERFAMILY SSF141523 61 195 4.45E-32 T 06-07-2017 CAK95_RS06310 77e3421a78f1736693be9b7dc1275212 397 Pfam PF07690 Major Facilitator Superfamily 15 355 5.8E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS06310 77e3421a78f1736693be9b7dc1275212 397 Gene3D G3DSA:1.20.1250.20 12 189 4.9E-27 T 06-07-2017 CAK95_RS06310 77e3421a78f1736693be9b7dc1275212 397 SUPERFAMILY SSF103473 6 391 6.41E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS06310 77e3421a78f1736693be9b7dc1275212 397 Gene3D G3DSA:1.20.1250.20 208 395 7.9E-9 T 06-07-2017 CAK95_RS06310 77e3421a78f1736693be9b7dc1275212 397 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 382 2.5E-80 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.1E-35 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Gene3D G3DSA:3.30.1490.20 120 187 3.0E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 SUPERFAMILY SSF52440 1 101 2.45E-35 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 SMART SM01210 326 420 1.4E-56 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 SUPERFAMILY SSF56059 102 318 1.57E-58 T 06-07-2017 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 7.0E-166 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 292 6.2E-77 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 418 1.3E-29 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 SUPERFAMILY SSF51246 325 420 1.41E-32 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 SMART SM01209 101 292 1.1E-134 T 06-07-2017 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 286 293 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Gene3D G3DSA:3.40.50.20 2 93 2.1E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 42.453 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Gene3D G3DSA:3.90.600.10 326 420 9.2E-38 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK95_RS13380 2afbf56aa76529c206a3987beb7a820d 427 Gene3D G3DSA:3.30.470.20 188 323 4.1E-59 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 SUPERFAMILY SSF55447 226 325 9.55E-28 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Gene3D G3DSA:3.30.465.10 157 219 3.0E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Gene3D G3DSA:3.30.465.10 56 113 3.0E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Gene3D G3DSA:3.30.43.10 1 51 2.7E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 SUPERFAMILY SSF56176 3 219 2.23E-63 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 323 1.1E-16 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 SMART SM01092 226 324 9.3E-28 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 1.8E-54 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS26215 c4b564e616c0f1bca3b74333385d489a 338 Gene3D G3DSA:3.30.390.50 225 326 3.8E-37 T 06-07-2017 CAK95_RS15255 ba872c1724c1da3581bc156c095fbb4f 135 Pfam PF14760 Rnk N-terminus 11 50 1.6E-7 T 06-07-2017 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain CAK95_RS15255 ba872c1724c1da3581bc156c095fbb4f 135 SUPERFAMILY SSF54534 58 131 3.79E-18 T 06-07-2017 CAK95_RS15255 ba872c1724c1da3581bc156c095fbb4f 135 Gene3D G3DSA:3.10.50.30 58 132 1.1E-25 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS15255 ba872c1724c1da3581bc156c095fbb4f 135 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 60 132 6.2E-22 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK95_RS27220 a7699205a1aeed232948da3fc280efb8 376 Pfam PF08309 LVIVD repeat 20 50 0.015 T 06-07-2017 IPR013211 LVIVD CAK95_RS27220 a7699205a1aeed232948da3fc280efb8 376 Pfam PF08309 LVIVD repeat 188 219 0.0014 T 06-07-2017 IPR013211 LVIVD CAK95_RS27220 a7699205a1aeed232948da3fc280efb8 376 Pfam PF08309 LVIVD repeat 90 111 1.6 T 06-07-2017 IPR013211 LVIVD CAK95_RS27220 a7699205a1aeed232948da3fc280efb8 376 Gene3D G3DSA:2.130.10.10 24 133 6.9E-4 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS27220 a7699205a1aeed232948da3fc280efb8 376 SUPERFAMILY SSF101908 9 211 2.22E-6 T 06-07-2017 CAK95_RS22165 398877e17d98f619265c1b8a12d6e104 249 Gene3D G3DSA:1.10.287.70 24 203 1.6E-25 T 06-07-2017 CAK95_RS22165 398877e17d98f619265c1b8a12d6e104 249 Pfam PF07885 Ion channel 139 206 2.0E-11 T 06-07-2017 IPR013099 Potassium channel domain CAK95_RS22165 398877e17d98f619265c1b8a12d6e104 249 SUPERFAMILY SSF81324 8 203 1.03E-23 T 06-07-2017 CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 Pfam PF12697 Alpha/beta hydrolase family 26 252 9.6E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 Gene3D G3DSA:3.40.50.1820 8 257 3.7E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 2.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 2.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS02135 2c64e3d048c140581a5e5488279394c0 269 SUPERFAMILY SSF53474 6 256 1.85E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Gene3D G3DSA:3.30.300.30 424 522 3.0E-23 T 06-07-2017 CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Gene3D G3DSA:3.40.50.980 188 340 3.9E-33 T 06-07-2017 CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Pfam PF00501 AMP-binding enzyme 26 429 2.4E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Gene3D G3DSA:3.40.50.980 19 187 2.6E-30 T 06-07-2017 CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 SUPERFAMILY SSF56801 17 523 1.44E-133 T 06-07-2017 CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 514 7.2E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS08115 f03bfb1ed8cf049ba55437a6a725ca01 529 Gene3D G3DSA:2.30.38.10 350 422 3.7E-25 T 06-07-2017 CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 Gene3D G3DSA:3.30.450.40 90 265 1.1E-45 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 SUPERFAMILY SSF55781 87 265 2.49E-39 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 SUPERFAMILY SSF46785 23 91 1.09E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 SMART SM00346 22 110 2.0E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 Pfam PF01614 Bacterial transcriptional regulator 141 263 3.9E-24 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 19 265 1.9E-87 T 06-07-2017 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 Pfam PF09339 IclR helix-turn-helix domain 24 75 5.9E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS09285 046a4bbbfecafc796684a5e46df1aa4d 266 Gene3D G3DSA:1.10.10.10 9 81 3.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26440 e78ae786a149f6851a86bed1a8b44f6e 125 Pfam PF00072 Response regulator receiver domain 6 117 1.1E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS26440 e78ae786a149f6851a86bed1a8b44f6e 125 SMART SM00448 4 117 3.8E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS26440 e78ae786a149f6851a86bed1a8b44f6e 125 SUPERFAMILY SSF52172 5 121 2.85E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS26440 e78ae786a149f6851a86bed1a8b44f6e 125 Gene3D G3DSA:3.40.50.2300 4 121 4.6E-25 T 06-07-2017 CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Gene3D G3DSA:2.60.40.10 375 497 1.0E-28 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Pfam PF13746 4Fe-4S dicluster domain 232 339 1.4E-39 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 287 298 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Pfam PF12801 4Fe-4S binding domain 110 143 1.2E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 SUPERFAMILY SSF54862 186 360 1.0E-27 T 06-07-2017 CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 SUPERFAMILY SSF54862 118 140 1.0E-27 T 06-07-2017 CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 49 472 1.4E-160 T 06-07-2017 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Gene3D G3DSA:1.10.1060.10 236 295 2.0E-7 T 06-07-2017 CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 375 497 1.8E-26 T 06-07-2017 IPR032879 FixG, C-terminal immunoglobulin-like domain CAK95_RS16705 1a8d0d865ceed55c0d42cb35baad6e1c 501 Gene3D G3DSA:3.30.70.20 296 323 7.1E-4 T 06-07-2017 CAK95_RS07495 89e17667440c67d34179b11718116042 321 Gene3D G3DSA:3.90.110.10 145 314 7.1E-62 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 SUPERFAMILY SSF56327 144 312 3.17E-56 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 309 1.6E-124 T 06-07-2017 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAK95_RS07495 89e17667440c67d34179b11718116042 321 Hamap MF_00487 Malate dehydrogenase [mdh]. 3 313 45.984 T 06-07-2017 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAK95_RS07495 89e17667440c67d34179b11718116042 321 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 307 3.8E-31 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 SUPERFAMILY SSF51735 5 144 1.32E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07495 89e17667440c67d34179b11718116042 321 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 2.5E-29 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 2.5E-29 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 2.5E-29 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 2.5E-29 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 2.5E-29 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 Gene3D G3DSA:3.40.50.720 2 144 1.4E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07495 89e17667440c67d34179b11718116042 321 PIRSF PIRSF000102 1 316 1.3E-101 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAK95_RS07495 89e17667440c67d34179b11718116042 321 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 143 7.7E-37 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 Gene3D G3DSA:2.40.50.100 62 139 4.0E-27 T 06-07-2017 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 Pfam PF00364 Biotin-requiring enzyme 66 138 8.2E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 95 112 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 139 2.7E-36 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 99 4.8E-12 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 113 4.8E-12 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 68 81 4.8E-12 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAK95_RS25245 ecb6c446cdfb615d228b29a87cddbc7e 139 SUPERFAMILY SSF51230 64 139 2.36E-23 T 06-07-2017 IPR011053 Single hybrid motif CAK95_RS22825 c94728e629e811617fd7d13b7e2541e1 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 121 20.254 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CAK95_RS22825 c94728e629e811617fd7d13b7e2541e1 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 120 2.3E-39 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 SMART SM01274 21 154 1.1E-76 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 SUPERFAMILY SSF51735 166 455 3.63E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Gene3D G3DSA:3.40.50.10750 571 727 1.1E-52 T 06-07-2017 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 SUPERFAMILY SSF53223 12 164 5.25E-52 T 06-07-2017 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Pfam PF01515 Phosphate acetyl/butaryl transferase 432 752 5.1E-97 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Pfam PF00390 Malic enzyme, N-terminal domain 22 154 1.4E-26 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Gene3D G3DSA:3.40.50.720 164 451 5.9E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25680 d8c255b691b9519040559d3625993684 760 PIRSF PIRSF036684 1 759 0.0 T 06-07-2017 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 SUPERFAMILY SSF53659 432 755 1.56E-91 T 06-07-2017 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Pfam PF03949 Malic enzyme, NAD binding domain 168 360 8.0E-20 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 SMART SM00919 166 403 3.3E-134 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK95_RS25680 d8c255b691b9519040559d3625993684 760 Gene3D G3DSA:3.40.50.10380 10 163 7.8E-50 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS15650 12e1e83dc978efdd73df185d5630999b 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 332 4.4E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15650 12e1e83dc978efdd73df185d5630999b 336 PIRSF PIRSF017082 7 336 3.2E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15650 12e1e83dc978efdd73df185d5630999b 336 SUPERFAMILY SSF53850 125 288 5.43E-11 T 06-07-2017 CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 Gene3D G3DSA:3.20.20.450 253 496 2.3E-42 T 06-07-2017 IPR001633 EAL domain CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 SMART SM00052 246 489 1.7E-12 T 06-07-2017 IPR001633 EAL domain CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 SUPERFAMILY SSF52172 123 207 2.85E-9 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 Pfam PF00072 Response regulator receiver domain 124 213 1.5E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 Gene3D G3DSA:3.40.50.2300 123 238 3.8E-10 T 06-07-2017 CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 SUPERFAMILY SSF141868 254 497 3.14E-41 T 06-07-2017 IPR001633 EAL domain CAK95_RS24275 e04ce592a13f4736197fd9983051d0f2 508 Pfam PF00563 EAL domain 253 484 4.6E-34 T 06-07-2017 IPR001633 EAL domain CAK95_RS11670 59ebee3806bd9e97c9976653fd544e17 433 Gene3D G3DSA:1.10.150.130 95 191 2.9E-10 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS11670 59ebee3806bd9e97c9976653fd544e17 433 Gene3D G3DSA:1.10.443.10 196 394 1.2E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS11670 59ebee3806bd9e97c9976653fd544e17 433 Pfam PF00589 Phage integrase family 202 383 7.5E-6 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS11670 59ebee3806bd9e97c9976653fd544e17 433 SUPERFAMILY SSF56349 94 391 1.68E-40 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS09995 4d79bef4e46e0d0f44b05853f85195c0 239 Pfam PF00005 ABC transporter 21 160 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09995 4d79bef4e46e0d0f44b05853f85195c0 239 SMART SM00382 30 210 7.8E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09995 4d79bef4e46e0d0f44b05853f85195c0 239 SUPERFAMILY SSF52540 5 227 5.88E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09995 4d79bef4e46e0d0f44b05853f85195c0 239 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09995 4d79bef4e46e0d0f44b05853f85195c0 239 Gene3D G3DSA:3.40.50.300 2 224 5.0E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 264 286 4.2E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 Pfam PF00005 ABC transporter 24 214 1.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 Gene3D G3DSA:3.40.50.300 4 287 5.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 SUPERFAMILY SSF52540 99 286 2.19E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 SUPERFAMILY SSF52540 7 68 2.19E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20300 1cbc007da5456bed9799c18d42fe6004 301 SMART SM00382 32 264 1.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23275 9431d7aa847a20c3f052a0ec6e59eb60 85 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 67 1.7E-33 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CAK95_RS23275 9431d7aa847a20c3f052a0ec6e59eb60 85 Gene3D G3DSA:2.30.30.100 5 77 3.3E-37 T 06-07-2017 CAK95_RS23275 9431d7aa847a20c3f052a0ec6e59eb60 85 SUPERFAMILY SSF50182 8 73 2.08E-25 T 06-07-2017 IPR010920 LSM domain CAK95_RS23275 9431d7aa847a20c3f052a0ec6e59eb60 85 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 67 29.926 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CAK95_RS05260 c6c89cb88153deb8822ef1491894a0ed 204 SMART SM00474 1 169 3.3E-36 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK95_RS05260 c6c89cb88153deb8822ef1491894a0ed 204 Gene3D G3DSA:3.30.420.10 18 176 6.2E-24 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS05260 c6c89cb88153deb8822ef1491894a0ed 204 Pfam PF01612 3'-5' exonuclease 18 168 2.7E-37 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK95_RS05260 c6c89cb88153deb8822ef1491894a0ed 204 SUPERFAMILY SSF53098 17 191 3.52E-53 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 SUPERFAMILY SSF55060 169 302 6.91E-23 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 11 303 28.696 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 Gene3D G3DSA:3.30.70.890 170 302 2.7E-26 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 Pfam PF00288 GHMP kinases N terminal domain 95 150 7.3E-8 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 Gene3D G3DSA:3.30.230.10 14 164 7.3E-42 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 SUPERFAMILY SSF54211 14 163 1.37E-33 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 15 283 9.8E-46 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 Pfam PF08544 GHMP kinases C terminal 215 291 2.9E-10 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK95_RS11150 af3cc2f6389114b664215a7086be46a2 311 PIRSF PIRSF010376 10 309 1.9E-74 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF48452 884 1114 8.85E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF55073 77 258 4.24E-45 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Pfam PF00536 SAM domain (Sterile alpha motif) 3 58 1.8E-13 T 06-07-2017 IPR001660 Sterile alpha motif domain GO:0005515 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF52540 404 531 2.05E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF52540 270 343 2.05E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:1.10.150.50 4 58 2.4E-16 T 06-07-2017 IPR013761 Sterile alpha motif/pointed domain CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:3.40.50.300 313 355 5.5E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:1.25.40.10 730 1017 3.1E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:3.30.70.1230 78 257 1.8E-32 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF48452 692 723 1.59E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF48452 764 847 1.59E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SUPERFAMILY SSF47769 3 59 5.24E-15 T 06-07-2017 IPR013761 Sterile alpha motif/pointed domain CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:3.40.50.300 278 312 2.5E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Gene3D G3DSA:3.40.50.300 368 470 2.5E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 78 248 1.9E-28 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SMART SM00044 47 238 4.2E-11 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 Pfam PF13191 AAA ATPase domain 276 464 2.0E-20 T 06-07-2017 CAK95_RS12425 3955c95640b193ea6fef59d2877ab2a3 1118 SMART SM00454 1 61 2.4E-10 T 06-07-2017 IPR001660 Sterile alpha motif domain GO:0005515 CAK95_RS13190 2b5eb2701f79dda0d14df8ed78753445 237 SUPERFAMILY SSF75708 61 236 9.68E-33 T 06-07-2017 CAK95_RS13190 2b5eb2701f79dda0d14df8ed78753445 237 Gene3D G3DSA:1.10.287.500 148 190 2.4E-11 T 06-07-2017 CAK95_RS13190 2b5eb2701f79dda0d14df8ed78753445 237 Pfam PF04344 Chemotaxis phosphatase, CheZ 125 236 2.1E-9 T 06-07-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CAK95_RS00305 fad0c8f01f6aaa2ceb5f764e6188910c 171 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 155 1.4E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS07190 5e32500d43d511954c799ad9a0a99d41 253 Gene3D G3DSA:3.90.226.10 5 250 9.6E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07190 5e32500d43d511954c799ad9a0a99d41 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 250 1.5E-45 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS07190 5e32500d43d511954c799ad9a0a99d41 253 SUPERFAMILY SSF52096 7 250 5.27E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 Pfam PF00120 Glutamine synthetase, catalytic domain 135 474 1.3E-80 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 SUPERFAMILY SSF55931 135 476 3.14E-90 T 06-07-2017 CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 SMART SM01230 133 397 7.7E-79 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 SUPERFAMILY SSF54368 20 132 3.66E-16 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 Gene3D G3DSA:3.10.20.70 20 134 1.6E-16 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK95_RS00935 aa6a3a278838934e7c590295ffdb540b 478 Gene3D G3DSA:3.30.590.10 136 464 1.7E-81 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK95_RS24805 4a17ef24cf20ded5851dde2816c77718 289 SMART SM00849 16 205 3.6E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24805 4a17ef24cf20ded5851dde2816c77718 289 SUPERFAMILY SSF56281 11 252 2.1E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24805 4a17ef24cf20ded5851dde2816c77718 289 Pfam PF00753 Metallo-beta-lactamase superfamily 14 205 9.3E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24805 4a17ef24cf20ded5851dde2816c77718 289 Gene3D G3DSA:3.60.15.10 8 251 3.0E-56 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 967 1114 8.7E-33 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Pfam PF00535 Glycosyl transferase family 2 536 650 2.0E-18 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Pfam PF00535 Glycosyl transferase family 2 305 432 2.7E-28 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Gene3D G3DSA:3.40.50.2000 966 1139 9.4E-45 T 06-07-2017 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Gene3D G3DSA:3.90.550.10 302 491 3.4E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Gene3D G3DSA:3.90.550.10 534 773 2.0E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 SUPERFAMILY SSF53448 302 491 5.16E-50 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 SUPERFAMILY SSF53756 820 1138 2.28E-60 T 06-07-2017 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 Gene3D G3DSA:3.40.50.2000 820 916 1.2E-11 T 06-07-2017 CAK95_RS26905 96f523cfbb11042bdac8bddc8af70ec6 1150 SUPERFAMILY SSF53448 532 765 2.5E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS16105 b89fb5c8d61cd815041562694117251a 257 Pfam PF04199 Putative cyclase 6 186 1.1E-34 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS16105 b89fb5c8d61cd815041562694117251a 257 Gene3D G3DSA:3.50.30.50 3 256 9.0E-60 T 06-07-2017 CAK95_RS16105 b89fb5c8d61cd815041562694117251a 257 SUPERFAMILY SSF102198 2 256 3.79E-56 T 06-07-2017 CAK95_RS23215 0404bf083361e60ce4d661cfa5416d7f 154 Pfam PF07007 Protein of unknown function (DUF1311) 61 144 4.6E-7 T 06-07-2017 IPR009739 Protein of unknown function DUF1311 CAK95_RS27965 f213913a8474f9a09895a9cf938a02de 142 SUPERFAMILY SSF140804 45 134 4.84E-24 T 06-07-2017 IPR027405 YidB-like CAK95_RS27965 f213913a8474f9a09895a9cf938a02de 142 Pfam PF06078 Bacterial protein of unknown function (DUF937) 13 125 2.0E-12 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS27965 f213913a8474f9a09895a9cf938a02de 142 Gene3D G3DSA:1.10.10.690 27 135 1.1E-26 T 06-07-2017 IPR027405 YidB-like CAK95_RS00730 fc1bc2984bf18c8f06e4d1e0905a21f0 231 Pfam PF08241 Methyltransferase domain 50 145 2.1E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS00730 fc1bc2984bf18c8f06e4d1e0905a21f0 231 Gene3D G3DSA:3.40.50.150 16 196 3.3E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00730 fc1bc2984bf18c8f06e4d1e0905a21f0 231 SUPERFAMILY SSF53335 15 205 2.48E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS12635 313d7238d614d6839030456182ba1de8 274 Pfam PF06629 MltA-interacting protein MipA 48 267 6.2E-45 T 06-07-2017 IPR010583 MltA-interacting MipA CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 SMART SM00342 202 285 1.2E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 Gene3D G3DSA:1.10.10.60 181 238 8.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 Pfam PF12833 Helix-turn-helix domain 208 281 2.0E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 SUPERFAMILY SSF46689 238 285 1.66E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 SUPERFAMILY SSF51215 49 166 3.79E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 Gene3D G3DSA:1.10.10.60 239 281 4.6E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 Pfam PF06719 AraC-type transcriptional regulator N-terminus 25 173 7.7E-41 T 06-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal CAK95_RS27625 da376a3fb8b843d02fe6f60f72d09678 295 SUPERFAMILY SSF46689 185 236 2.5E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03380 9972fb2a661b1b670b022f1579307cc2 226 Gene3D G3DSA:3.40.50.850 8 208 4.3E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS03380 9972fb2a661b1b670b022f1579307cc2 226 SUPERFAMILY SSF52499 6 206 1.7E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS03380 9972fb2a661b1b670b022f1579307cc2 226 Pfam PF00857 Isochorismatase family 14 167 9.5E-28 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 Gene3D G3DSA:3.40.190.10 115 228 1.9E-18 T 06-07-2017 CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 2 315 1.4E-49 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 SUPERFAMILY SSF53850 24 318 6.12E-52 T 06-07-2017 CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 Gene3D G3DSA:3.40.190.10 243 317 2.9E-32 T 06-07-2017 CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 Gene3D G3DSA:3.40.190.10 24 103 2.9E-32 T 06-07-2017 CAK95_RS28795 e84dfe5459ea7c52af7090904fe36ffe 320 Pfam PF16868 NMT1-like family 41 315 1.1E-38 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 6.0E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 SUPERFAMILY SSF51735 19 263 3.73E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 263 3.3E-63 T 06-07-2017 CAK95_RS15070 5e25197ea27354ca8f401b90963a744b 265 Gene3D G3DSA:3.40.50.720 15 263 7.4E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27355 9572da77d2810d1a828305e06e5ebf48 264 SUPERFAMILY SSF161098 63 240 2.49E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27355 9572da77d2810d1a828305e06e5ebf48 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 253 1.1E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27355 9572da77d2810d1a828305e06e5ebf48 264 Gene3D G3DSA:1.10.3720.10 67 252 1.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16970 affacd73f5ea8ac90ae692480f32d28d 464 Pfam PF01425 Amidase 26 441 1.9E-99 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16970 affacd73f5ea8ac90ae692480f32d28d 464 SUPERFAMILY SSF75304 2 462 7.59E-129 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16970 affacd73f5ea8ac90ae692480f32d28d 464 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 10 456 2.6E-220 T 06-07-2017 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 CAK95_RS16970 affacd73f5ea8ac90ae692480f32d28d 464 Gene3D G3DSA:3.90.1300.10 5 462 5.7E-136 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS11280 39a1449725c6ffa2896f26ee9e4ba916 234 Gene3D G3DSA:3.40.1050.10 36 233 4.2E-52 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS11280 39a1449725c6ffa2896f26ee9e4ba916 234 Pfam PF00484 Carbonic anhydrase 83 231 1.3E-38 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS11280 39a1449725c6ffa2896f26ee9e4ba916 234 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 87 94 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS11280 39a1449725c6ffa2896f26ee9e4ba916 234 SMART SM00947 75 234 4.5E-53 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS11280 39a1449725c6ffa2896f26ee9e4ba916 234 SUPERFAMILY SSF53056 37 234 3.4E-54 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS07925 84e23e2e252dc7d8c1d39ac3b0898c79 257 SUPERFAMILY SSF161098 51 233 8.76E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07925 84e23e2e252dc7d8c1d39ac3b0898c79 257 Gene3D G3DSA:1.10.3720.10 50 244 6.3E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07925 84e23e2e252dc7d8c1d39ac3b0898c79 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 240 2.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Gene3D G3DSA:3.30.70.870 402 469 5.4E-10 T 06-07-2017 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 SUPERFAMILY SSF54980 400 470 3.45E-13 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Gene3D G3DSA:2.40.30.10 300 401 1.4E-22 T 06-07-2017 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 27 165 4.1E-24 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Pfam PF03144 Elongation factor Tu domain 2 321 387 1.3E-8 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 SUPERFAMILY SSF50447 268 400 1.32E-27 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Pfam PF00009 Elongation factor Tu GTP binding domain 23 284 2.3E-48 T 06-07-2017 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Pfam PF16658 Class II release factor RF3, C-terminal domain 394 521 8.4E-41 T 06-07-2017 IPR032090 Peptide chain release factor 3, C-terminal CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 15 534 49.967 T 06-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 Gene3D G3DSA:3.40.50.300 20 290 2.1E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 69 84 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 PRINTS PR00315 GTP-binding elongation factor signature 26 39 5.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 PRINTS PR00315 GTP-binding elongation factor signature 148 157 5.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 PRINTS PR00315 GTP-binding elongation factor signature 112 123 5.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 PRINTS PR00315 GTP-binding elongation factor signature 76 84 5.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 PRINTS PR00315 GTP-binding elongation factor signature 96 106 5.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 SUPERFAMILY SSF52540 20 284 1.93E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24050 ad3e68ba29020e7cb798413ad5ad2919 541 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 17 534 1.3E-203 T 06-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 Pfam PF00924 Mechanosensitive ion channel 502 702 1.4E-44 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 SUPERFAMILY SSF82689 613 712 6.8E-22 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 SUPERFAMILY SSF82861 460 543 5.23E-14 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 SUPERFAMILY SSF50182 545 607 4.25E-13 T 06-07-2017 IPR010920 LSM domain CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 Gene3D G3DSA:3.30.70.100 616 700 5.8E-12 T 06-07-2017 CAK95_RS26255 78854279c23b9e63601c507ace1a91c6 773 Gene3D G3DSA:2.30.30.60 561 606 1.4E-12 T 06-07-2017 CAK95_RS10005 0152fe643e43252894c8bfc1d21930d4 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 301 3.4E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 Gene3D G3DSA:1.10.10.10 12 90 6.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 Gene3D G3DSA:1.20.120.530 95 231 2.0E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 SUPERFAMILY SSF48008 96 231 3.4E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 SUPERFAMILY SSF46785 23 93 1.72E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 Pfam PF07729 FCD domain 100 222 1.3E-27 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 SMART SM00345 31 89 1.5E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 89 4.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS10665 b6982ef3683bad118f174f88bd01042e 245 SMART SM00895 99 223 1.1E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 Gene3D G3DSA:1.10.10.10 19 77 1.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 SMART SM00345 22 81 2.7E-25 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 SUPERFAMILY SSF64288 69 246 1.08E-37 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 SMART SM00866 102 242 5.1E-26 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 14 247 4.8E-85 T 06-07-2017 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 SUPERFAMILY SSF46785 16 89 9.52E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 Pfam PF07702 UTRA domain 103 241 3.5E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 Gene3D G3DSA:3.40.1410.10 78 246 4.2E-36 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS27930 66e95600d21a387e64784591339a25a5 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 1.3E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS22240 ab277eb71ae645e69474c2ca939d9ef7 207 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 202 4.7E-51 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS22240 ab277eb71ae645e69474c2ca939d9ef7 207 Pfam PF01914 MarC family integral membrane protein 3 204 2.4E-53 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 SMART SM00955 265 596 2.1E-152 T 06-07-2017 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 Pfam PF00773 RNB domain 265 595 7.7E-90 T 06-07-2017 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 SUPERFAMILY SSF50249 235 642 1.03E-126 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 TIGRFAM TIGR02063 RNase_R: ribonuclease R 13 726 2.9E-213 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 SMART SM00316 643 726 1.8E-7 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 Pfam PF00575 S1 RNA binding domain 643 713 1.6E-8 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 Gene3D G3DSA:1.10.10.10 17 71 3.8E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 SUPERFAMILY SSF50249 643 724 7.35E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 Hamap MF_01895 Ribonuclease R [rnr]. 32 726 54.223 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 Gene3D G3DSA:2.40.50.140 645 719 2.1E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 126 713 6.5E-148 T 06-07-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CAK95_RS22060 465a3643795610d9605d83efcc26eed6 763 ProSitePatterns PS01175 Ribonuclease II family signature. 563 587 - T 06-07-2017 IPR022966 Ribonuclease II/R, conserved site CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 PIRSF PIRSF000151 10 430 1.5E-167 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 Gene3D G3DSA:3.40.309.10 240 387 7.6E-35 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 Pfam PF00171 Aldehyde dehydrogenase family 20 294 1.8E-14 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 Gene3D G3DSA:3.40.605.10 11 237 6.7E-97 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 Gene3D G3DSA:3.40.605.10 388 429 6.7E-97 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 25 419 5.0E-135 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 17 429 39.396 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 336 357 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS07320 7288bbc1598d8e8dcd4108a266aa181f 430 SUPERFAMILY SSF53720 18 429 1.7E-109 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS09675 b5106b271a8363b293b5352541023d6d 239 SUPERFAMILY SSF52218 7 227 4.42E-65 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS09675 b5106b271a8363b293b5352541023d6d 239 Gene3D G3DSA:3.40.50.360 8 228 4.2E-103 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS09675 b5106b271a8363b293b5352541023d6d 239 Pfam PF03358 NADPH-dependent FMN reductase 33 176 4.4E-27 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS09675 b5106b271a8363b293b5352541023d6d 239 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 8 225 5.0E-127 T 06-07-2017 IPR014063 Arsenate resistance ArsH CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 Gene3D G3DSA:1.50.10.20 1283 1530 8.2E-29 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 PIRSF PIRSF038980 11 1743 0.0 T 06-07-2017 IPR026284 Alpha-2-macroglobulin domain protein, bacteria CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 SUPERFAMILY SSF48239 1283 1532 8.52E-39 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 SMART SM01360 1080 1169 6.2E-22 T 06-07-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 Pfam PF01835 MG2 domain 518 613 9.7E-21 T 06-07-2017 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 875 1019 1.0E-8 T 06-07-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 Pfam PF00207 Alpha-2-macroglobulin family 1082 1161 1.0E-6 T 06-07-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 SMART SM01359 875 1019 1.1E-26 T 06-07-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CAK95_RS24255 775dd097579494535b6402f4d8e0de40 1743 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 412 512 8.7E-26 T 06-07-2017 IPR021868 Alpha-2-macroglobulin MG1 domain CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:3.30.70.20 367 368 3.4E-14 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:3.30.70.20 526 543 3.4E-14 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:3.30.70.20 544 583 2.8E-6 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 506 517 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 SUPERFAMILY SSF54862 501 605 4.51E-41 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 SUPERFAMILY SSF54862 241 316 4.51E-41 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:3.30.70.20 246 300 4.7E-13 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 537 548 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:1.10.1060.10 301 331 1.9E-11 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:1.10.1060.10 498 520 1.9E-11 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Gene3D G3DSA:1.10.1060.10 382 383 1.9E-11 T 06-07-2017 CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Pfam PF12838 4Fe-4S dicluster domain 267 309 1.2E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 295 306 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS27870 2a5f7b9d1e5b5157d47f203a05fc8047 658 Pfam PF13187 4Fe-4S dicluster domain 506 552 3.6E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS19775 e9a41b7a87ae4bea00ccec659d9983f7 352 Gene3D G3DSA:1.10.443.10 171 343 1.3E-32 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS19775 e9a41b7a87ae4bea00ccec659d9983f7 352 Pfam PF00589 Phage integrase family 174 339 8.1E-22 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS19775 e9a41b7a87ae4bea00ccec659d9983f7 352 SUPERFAMILY SSF56349 73 343 7.95E-45 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS09865 61cf09feecb7333a06d73edb5d9e8e1e 408 Gene3D G3DSA:3.40.50.2000 206 293 2.9E-6 T 06-07-2017 CAK95_RS09865 61cf09feecb7333a06d73edb5d9e8e1e 408 Pfam PF13692 Glycosyl transferases group 1 211 355 1.1E-15 T 06-07-2017 CAK95_RS09865 61cf09feecb7333a06d73edb5d9e8e1e 408 Pfam PF13477 Glycosyl transferase 4-like 5 164 5.7E-15 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS09865 61cf09feecb7333a06d73edb5d9e8e1e 408 SUPERFAMILY SSF53756 17 389 1.52E-44 T 06-07-2017 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 15 249 1.0E-65 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 Gene3D G3DSA:3.30.200.20 17 103 7.9E-38 T 06-07-2017 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 SUPERFAMILY SSF56104 10 246 7.19E-79 T 06-07-2017 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 Pfam PF01259 SAICAR synthetase 16 245 2.0E-61 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 ProSitePatterns PS01057 SAICAR synthetase signature 1. 96 110 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 14 248 32.246 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK95_RS26530 ef3d762009f9d132873303a210806aa6 265 Gene3D G3DSA:3.30.470.20 104 233 2.0E-50 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS27600 5c4047dd452dc12dced7398fc828020f 567 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 560 1.9E-231 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK95_RS27600 5c4047dd452dc12dced7398fc828020f 567 PIRSF PIRSF001294 1 563 2.0E-241 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK95_RS27600 5c4047dd452dc12dced7398fc828020f 567 Pfam PF03814 Potassium-transporting ATPase A subunit 11 559 2.1E-245 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK95_RS27600 5c4047dd452dc12dced7398fc828020f 567 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 561 35.928 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK95_RS16975 ac812302eccd75f5ef7bbfff9cab0563 130 Gene3D G3DSA:3.10.450.50 1 126 4.3E-57 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS16975 ac812302eccd75f5ef7bbfff9cab0563 130 SUPERFAMILY SSF54427 1 124 3.6E-37 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS16975 ac812302eccd75f5ef7bbfff9cab0563 130 Pfam PF11533 Protein of unknown function (DUF3225) 1 126 5.8E-59 T 06-07-2017 IPR024507 Protein of unknown function DUF3225 CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 Gene3D G3DSA:3.90.180.10 2 139 1.1E-57 T 06-07-2017 IPR011032 GroES-like CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 SMART SM00829 20 335 1.2E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 SUPERFAMILY SSF51735 124 303 1.14E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 Gene3D G3DSA:3.40.50.720 140 305 9.2E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 Pfam PF16884 N-terminal domain of oxidoreductase 6 113 6.2E-42 T 06-07-2017 CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 Pfam PF00107 Zinc-binding dehydrogenase 158 292 5.2E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS26290 ca90162a158fab46362993889cb9830b 342 SUPERFAMILY SSF50129 4 143 1.83E-42 T 06-07-2017 IPR011032 GroES-like CAK95_RS06765 18cd6b045de2757eac4bfc2b57aa93cc 289 SUPERFAMILY SSF53167 17 275 1.27E-60 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS06765 18cd6b045de2757eac4bfc2b57aa93cc 289 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 35 274 2.6E-61 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CAK95_RS06765 18cd6b045de2757eac4bfc2b57aa93cc 289 Pfam PF01048 Phosphorylase superfamily 36 276 1.8E-38 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS06765 18cd6b045de2757eac4bfc2b57aa93cc 289 Gene3D G3DSA:3.40.50.1580 15 275 6.7E-64 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS21210 d8b24aa77254c5c93b5da9579eca99da 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 159 25.586 T 06-07-2017 IPR022973 Ribosomal protein L10 CAK95_RS21210 d8b24aa77254c5c93b5da9579eca99da 172 SUPERFAMILY SSF160369 2 169 4.84E-54 T 06-07-2017 CAK95_RS21210 d8b24aa77254c5c93b5da9579eca99da 172 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21210 d8b24aa77254c5c93b5da9579eca99da 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 141 1.0E-10 T 06-07-2017 CAK95_RS21210 d8b24aa77254c5c93b5da9579eca99da 172 Pfam PF00466 Ribosomal protein L10 2 99 5.1E-28 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CAK95_RS20655 bb12d6ceeaaa279965fb923d38b6f450 128 Gene3D G3DSA:3.40.50.2300 2 125 8.2E-28 T 06-07-2017 CAK95_RS20655 bb12d6ceeaaa279965fb923d38b6f450 128 Pfam PF00072 Response regulator receiver domain 4 121 2.1E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20655 bb12d6ceeaaa279965fb923d38b6f450 128 SUPERFAMILY SSF52172 1 125 4.13E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS20655 bb12d6ceeaaa279965fb923d38b6f450 128 SMART SM00448 2 120 2.9E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 SUPERFAMILY SSF52096 8 319 3.38E-93 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 8 321 47.271 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 158 171 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 93 104 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 174 187 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 118 136 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 202 211 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 139 155 2.9E-40 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 Gene3D G3DSA:3.90.226.10 61 275 1.0E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 6 320 1.5E-123 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10485 a2c20c3bb303599a8d6b0d8823aacc73 323 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 8 153 6.0E-61 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS28125 137fd11752f0003dc02f7c17d1fab06c 342 Pfam PF00892 EamA-like transporter family 196 331 3.2E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS28125 137fd11752f0003dc02f7c17d1fab06c 342 Pfam PF00892 EamA-like transporter family 48 181 2.1E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS28125 137fd11752f0003dc02f7c17d1fab06c 342 SUPERFAMILY SSF103481 239 335 2.75E-13 T 06-07-2017 CAK95_RS28125 137fd11752f0003dc02f7c17d1fab06c 342 SUPERFAMILY SSF103481 81 184 1.96E-12 T 06-07-2017 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 74 12.618 T 06-07-2017 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 SUPERFAMILY SSF81333 4 74 2.35E-16 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 PRINTS PR00124 ATP synthase C subunit signature 30 45 3.1E-21 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 PRINTS PR00124 ATP synthase C subunit signature 9 28 3.1E-21 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 PRINTS PR00124 ATP synthase C subunit signature 47 72 3.1E-21 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 Gene3D G3DSA:1.20.20.10 5 74 2.6E-18 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK95_RS05540 7cdd07da2d25ce4a634eef8bb1e995ff 75 Pfam PF00137 ATP synthase subunit C 9 71 2.5E-10 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAK95_RS24395 3397d6a19318ac0fabaccbd79c35da60 721 SUPERFAMILY SSF56235 70 170 8.49E-10 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS24395 3397d6a19318ac0fabaccbd79c35da60 721 Gene3D G3DSA:3.60.20.10 71 166 5.2E-10 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 PIRSF PIRSF000331 1 480 1.4E-95 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 Gene3D G3DSA:1.20.140.10 261 475 3.7E-48 T 06-07-2017 CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 SUPERFAMILY SSF47203 259 475 1.74E-63 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 267 2.7E-77 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 Gene3D G3DSA:1.10.3140.10 1 140 2.3E-32 T 06-07-2017 CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 SUPERFAMILY SSF56645 1 269 1.83E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 Gene3D G3DSA:2.40.110.10 146 260 1.0E-39 T 06-07-2017 CAK95_RS16900 77fcf0db7c22063d7a494000b40ae7d1 484 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 278 474 1.6E-53 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal CAK95_RS00185 1bfda695f021f4311d8c85d5e7b7ebb0 364 SUPERFAMILY SSF89733 2 351 2.88E-95 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS00185 1bfda695f021f4311d8c85d5e7b7ebb0 364 Pfam PF02615 Malate/L-lactate dehydrogenase 5 342 1.8E-98 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS00185 1bfda695f021f4311d8c85d5e7b7ebb0 364 Gene3D G3DSA:1.10.1530.10 3 72 4.5E-18 T 06-07-2017 CAK95_RS00185 1bfda695f021f4311d8c85d5e7b7ebb0 364 Gene3D G3DSA:3.30.1370.60 73 281 8.7E-66 T 06-07-2017 CAK95_RS02735 ff03ca25db8fe30d293f78d3454e3c41 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02735 ff03ca25db8fe30d293f78d3454e3c41 324 PIRSF PIRSF017082 1 323 4.7E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02735 ff03ca25db8fe30d293f78d3454e3c41 324 SUPERFAMILY SSF53850 42 222 4.19E-10 T 06-07-2017 CAK95_RS15370 3181633f8fdaa218eee4a55c0e9c2b1b 476 Pfam PF02120 Flagellar hook-length control protein FliK 349 430 4.5E-19 T 06-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal CAK95_RS19885 655e94fc8000424c9cb7899a2fe61846 128 Pfam PF06155 Protein of unknown function (DUF971) 13 96 7.6E-29 T 06-07-2017 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 CAK95_RS08025 00b3588a3aefe23ae88795ef180709cd 729 Pfam PF07715 TonB-dependent Receptor Plug Domain 79 180 1.4E-19 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS08025 00b3588a3aefe23ae88795ef180709cd 729 SUPERFAMILY SSF56935 78 729 2.49E-75 T 06-07-2017 CAK95_RS08025 00b3588a3aefe23ae88795ef180709cd 729 Pfam PF00593 TonB dependent receptor 488 727 7.0E-21 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS08025 00b3588a3aefe23ae88795ef180709cd 729 Gene3D G3DSA:2.40.170.20 198 729 2.3E-47 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS08025 00b3588a3aefe23ae88795ef180709cd 729 Gene3D G3DSA:2.170.130.10 25 185 2.1E-28 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 SUPERFAMILY SSF52964 45 179 1.7E-44 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Pfam PF04052 TolB amino-terminal domain 40 146 1.9E-34 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 SUPERFAMILY SSF69304 172 446 3.79E-58 T 06-07-2017 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Gene3D G3DSA:3.40.50.10070 40 169 6.6E-52 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Hamap MF_00671 Protein TolB [tolB]. 27 444 31.735 T 06-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Pfam PF07676 WD40-like Beta Propeller Repeat 344 377 2.2E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Pfam PF07676 WD40-like Beta Propeller Repeat 259 290 9.8E-5 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Pfam PF07676 WD40-like Beta Propeller Repeat 387 421 1.4E-6 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Pfam PF07676 WD40-like Beta Propeller Repeat 300 335 1.3E-11 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 Gene3D G3DSA:2.130.10.10 170 446 7.7E-76 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS03995 5596364dd75f2c4c461677de198d7d71 449 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 34 445 2.8E-147 T 06-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CAK95_RS07170 750261d2b8e7bb93bf1c544468ca8ef2 272 Gene3D G3DSA:3.90.226.10 1 237 5.9E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07170 750261d2b8e7bb93bf1c544468ca8ef2 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 229 8.0E-48 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS07170 750261d2b8e7bb93bf1c544468ca8ef2 272 SUPERFAMILY SSF52096 1 243 1.05E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 SUPERFAMILY SSF52518 381 562 3.32E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 SUPERFAMILY SSF52467 207 372 8.8E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 191 2.5E-45 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Gene3D G3DSA:3.40.50.1220 206 359 2.1E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 215 343 1.7E-32 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Gene3D G3DSA:3.40.50.970 381 563 9.3E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 SUPERFAMILY SSF52518 23 193 1.67E-42 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Gene3D G3DSA:3.40.50.970 24 192 2.4E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 21 574 0.0 T 06-07-2017 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696 CAK95_RS12750 6d690c11034a6b2c33c7167cfc18e114 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 411 554 7.1E-24 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS00060 8f7821dabc3388caefd2f4b8d21b7823 157 SUPERFAMILY SSF54637 4 147 1.69E-35 T 06-07-2017 IPR029069 HotDog domain CAK95_RS00060 8f7821dabc3388caefd2f4b8d21b7823 157 Gene3D G3DSA:3.10.129.10 3 143 5.8E-39 T 06-07-2017 IPR029069 HotDog domain CAK95_RS00060 8f7821dabc3388caefd2f4b8d21b7823 157 Pfam PF01575 MaoC like domain 18 121 2.6E-20 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 292 2.8E-23 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 167 2.4E-30 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 PIRSF PIRSF000103 11 303 3.4E-57 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 Gene3D G3DSA:1.10.1040.10 173 301 3.0E-34 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 SUPERFAMILY SSF48179 172 301 4.35E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 SUPERFAMILY SSF51735 14 165 1.9E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16170 48d62c5e803701b1c0d17f45c8532248 312 Gene3D G3DSA:3.40.50.720 14 170 6.0E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28410 791b9f08ec22aad6556779025db44395 50 SUPERFAMILY SSF81469 11 49 3.92E-10 T 06-07-2017 IPR012422 Cytochrome c oxidase, subunit IV, bacterial aa3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS28410 791b9f08ec22aad6556779025db44395 50 Gene3D G3DSA:1.20.5.160 16 48 9.6E-6 T 06-07-2017 IPR012422 Cytochrome c oxidase, subunit IV, bacterial aa3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS28410 791b9f08ec22aad6556779025db44395 50 Pfam PF07835 Bacterial aa3 type cytochrome c oxidase subunit IV 4 49 5.8E-18 T 06-07-2017 IPR012422 Cytochrome c oxidase, subunit IV, bacterial aa3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS08255 de89b0868b1889cebb371404567ad7df 325 SUPERFAMILY SSF51735 1 317 2.22E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08255 de89b0868b1889cebb371404567ad7df 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 203 2.2E-21 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS08255 de89b0868b1889cebb371404567ad7df 325 Gene3D G3DSA:3.40.50.720 1 180 2.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08255 de89b0868b1889cebb371404567ad7df 325 Gene3D G3DSA:3.90.25.10 181 300 1.9E-34 T 06-07-2017 CAK95_RS16585 fcae17ef1fb0988df2b7a858e88a9ee3 444 Gene3D G3DSA:1.20.1250.20 255 428 1.8E-11 T 06-07-2017 CAK95_RS16585 fcae17ef1fb0988df2b7a858e88a9ee3 444 Pfam PF07690 Major Facilitator Superfamily 51 271 1.6E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS16585 fcae17ef1fb0988df2b7a858e88a9ee3 444 Gene3D G3DSA:1.20.1250.20 44 229 6.9E-27 T 06-07-2017 CAK95_RS16585 fcae17ef1fb0988df2b7a858e88a9ee3 444 SUPERFAMILY SSF103473 38 428 4.58E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS07160 afe14f073009841ce69ff2bf7174d3c9 259 Gene3D G3DSA:1.10.230.10 145 208 1.9E-6 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAK95_RS07160 afe14f073009841ce69ff2bf7174d3c9 259 Gene3D G3DSA:1.10.580.10 45 144 8.1E-11 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK95_RS07160 afe14f073009841ce69ff2bf7174d3c9 259 SUPERFAMILY SSF48256 50 240 1.19E-41 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS07160 afe14f073009841ce69ff2bf7174d3c9 259 Pfam PF00285 Citrate synthase, C-terminal domain 43 239 4.6E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK95_RS15595 ced0c7cae82bf978c9d491c81c5ce186 376 Gene3D G3DSA:3.40.50.2300 20 147 4.5E-38 T 06-07-2017 CAK95_RS15595 ced0c7cae82bf978c9d491c81c5ce186 376 Gene3D G3DSA:3.40.50.2300 305 357 4.5E-38 T 06-07-2017 CAK95_RS15595 ced0c7cae82bf978c9d491c81c5ce186 376 SUPERFAMILY SSF53822 25 374 1.09E-61 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS15595 ced0c7cae82bf978c9d491c81c5ce186 376 Gene3D G3DSA:3.40.50.2300 151 304 2.6E-18 T 06-07-2017 CAK95_RS15595 ced0c7cae82bf978c9d491c81c5ce186 376 Pfam PF13458 Periplasmic binding protein 25 371 9.7E-49 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS09105 84bd1b40ffdc35a98c82a7106f549387 173 Gene3D G3DSA:1.10.10.10 39 120 5.0E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09105 84bd1b40ffdc35a98c82a7106f549387 173 Pfam PF01475 Ferric uptake regulator family 48 162 9.2E-21 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAK95_RS09105 84bd1b40ffdc35a98c82a7106f549387 173 SUPERFAMILY SSF46785 40 164 1.05E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02170 53195825fbb9c5d2353692af2100bb8b 382 Pfam PF13458 Periplasmic binding protein 23 372 1.1E-57 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS02170 53195825fbb9c5d2353692af2100bb8b 382 Gene3D G3DSA:3.40.50.2300 23 216 9.9E-47 T 06-07-2017 CAK95_RS02170 53195825fbb9c5d2353692af2100bb8b 382 SUPERFAMILY SSF53822 23 380 8.9E-77 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS04010 3a912cc2f806b5ed649e9a9cdba3b634 237 TIGRFAM TIGR02796 tolQ: protein TolQ 18 230 3.3E-86 T 06-07-2017 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 CAK95_RS04010 3a912cc2f806b5ed649e9a9cdba3b634 237 Pfam PF01618 MotA/TolQ/ExbB proton channel family 89 218 2.5E-40 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 Gene3D G3DSA:3.40.50.720 573 707 5.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 SUPERFAMILY SSF51735 577 714 1.62E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 SUPERFAMILY SSF51735 412 547 3.31E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 Pfam PF00999 Sodium/hydrogen exchanger family 12 371 2.9E-48 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 Gene3D G3DSA:3.40.50.720 411 548 6.1E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 Pfam PF02254 TrkA-N domain 579 692 1.8E-23 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK95_RS09095 d836942c5b6d82e96fa2085eb0436704 757 Pfam PF02254 TrkA-N domain 412 535 3.1E-15 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK95_RS01605 fc5f639bb938baded076c922e2569c3c 252 Gene3D G3DSA:3.90.730.10 58 248 1.6E-40 T 06-07-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 CAK95_RS01605 fc5f639bb938baded076c922e2569c3c 252 SUPERFAMILY SSF55895 60 248 6.15E-41 T 06-07-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 CAK95_RS01605 fc5f639bb938baded076c922e2569c3c 252 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 99 106 - T 06-07-2017 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 CAK95_RS01605 fc5f639bb938baded076c922e2569c3c 252 Pfam PF00445 Ribonuclease T2 family 64 231 1.9E-15 T 06-07-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 CAK95_RS10635 024b4fc92ac251256d5bcf42a91a3594 326 SUPERFAMILY SSF51556 11 320 1.49E-56 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS10635 024b4fc92ac251256d5bcf42a91a3594 326 Gene3D G3DSA:3.20.20.140 11 322 2.7E-60 T 06-07-2017 CAK95_RS10635 024b4fc92ac251256d5bcf42a91a3594 326 Pfam PF04909 Amidohydrolase 11 320 2.3E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS05380 e54a961441b84878239089cf4b2e2d5a 380 PIRSF PIRSF038991 18 366 2.4E-70 T 06-07-2017 IPR007820 AbrB family GO:0010468|GO:0016021 CAK95_RS05380 e54a961441b84878239089cf4b2e2d5a 380 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 205 360 2.3E-29 T 06-07-2017 IPR017516 AbrB duplication CAK95_RS05380 e54a961441b84878239089cf4b2e2d5a 380 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 31 184 1.9E-32 T 06-07-2017 IPR017516 AbrB duplication CAK95_RS05380 e54a961441b84878239089cf4b2e2d5a 380 Pfam PF05145 Putative ammonia monooxygenase 53 360 8.8E-70 T 06-07-2017 IPR007820 AbrB family GO:0010468|GO:0016021 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.2E-52 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CAK95_RS21180 9691d256fb842072407f04979b49b054 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 229 42.132 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 5 227 7.3E-98 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 SUPERFAMILY SSF56808 6 226 2.75E-82 T 06-07-2017 IPR023674 Ribosomal protein L1-like CAK95_RS21180 9691d256fb842072407f04979b49b054 233 Gene3D G3DSA:3.40.50.790 69 159 2.3E-40 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CAK95_RS21180 9691d256fb842072407f04979b49b054 233 Gene3D G3DSA:3.30.190.20 161 226 7.9E-47 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 Gene3D G3DSA:3.30.190.20 16 68 7.9E-47 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 PIRSF PIRSF002155 1 227 7.4E-78 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21180 9691d256fb842072407f04979b49b054 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 Gene3D G3DSA:3.30.1220.10 242 353 1.1E-28 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 SUPERFAMILY SSF52540 14 201 4.63E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 353 9.1E-18 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 SMART SM00833 258 353 1.2E-26 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 SUPERFAMILY SSF90002 258 353 4.32E-19 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 17 199 5.5E-44 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK95_RS04725 715a85614dbeaec4d1a7c29f772642df 379 Gene3D G3DSA:3.40.50.300 15 220 6.2E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04220 e159192c8dc267d4f88f44c0d89d348e 171 Pfam PF07323 Protein of unknown function (DUF1465) 17 168 2.2E-58 T 06-07-2017 IPR010848 Protein of unknown function DUF1465 CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 22 489 1.9E-150 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 SUPERFAMILY SSF52540 198 479 1.41E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 SMART SM00382 217 430 2.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 Gene3D G3DSA:1.10.860.10 23 123 1.1E-24 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 Gene3D G3DSA:3.40.50.300 188 489 4.3E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 Pfam PF00772 DnaB-like helicase N terminal domain 22 123 2.3E-25 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 SUPERFAMILY SSF48024 20 131 7.98E-30 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAK95_RS25940 4b43c4af967067adb1d17b5d398eace0 497 Pfam PF03796 DnaB-like helicase C terminal domain 200 486 5.4E-98 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 Gene3D G3DSA:3.30.300.70 21 97 5.0E-23 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 SUPERFAMILY SSF74942 101 175 1.02E-14 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 SUPERFAMILY SSF75420 17 100 5.49E-21 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 23 174 22.073 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 Gene3D G3DSA:2.30.30.180 106 171 1.3E-9 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal CAK95_RS09180 c840c47a39b2ef222b6115d823f110c4 254 Pfam PF02576 Putative ribosome maturation factor RimP 29 170 1.2E-38 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAK95_RS02335 89bc80d65a4de08af45bc0d6ba4861ac 118 TIGRFAM TIGR04360 other_trbK: conjugative transfer region protein TrbK 14 86 5.1E-18 T 06-07-2017 IPR027587 Conjugative transfer region protein TrbK CAK95_RS15270 a2821a7151473987658bfaaeff7287ed 147 SUPERFAMILY SSF54637 21 144 6.13E-21 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15270 a2821a7151473987658bfaaeff7287ed 147 Gene3D G3DSA:3.10.129.10 22 146 3.5E-37 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15270 a2821a7151473987658bfaaeff7287ed 147 Pfam PF03061 Thioesterase superfamily 61 132 5.7E-9 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 Pfam PF01037 Lrp/AsnC ligand binding domain 71 145 2.1E-27 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 SUPERFAMILY SSF54909 65 154 1.23E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 7.8E-20 T 06-07-2017 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.9E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.9E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.9E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 SUPERFAMILY SSF46785 4 64 3.91E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 Gene3D G3DSA:1.10.10.10 1 56 1.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 Gene3D G3DSA:3.30.70.920 58 142 1.9E-31 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 SMART SM00344 5 114 8.7E-48 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS06955 ffd8ef72ca5761590f0a4e0961629529 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 325 1.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SUPERFAMILY SSF55874 316 480 3.67E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SUPERFAMILY SSF47384 256 325 3.53E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SMART SM00091 121 187 3.3E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SUPERFAMILY SSF55785 132 246 2.49E-29 T 06-07-2017 IPR000014 PAS domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SMART SM00387 372 481 6.0E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 480 4.9E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 SMART SM00388 259 330 4.9E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Gene3D G3DSA:1.10.287.130 258 324 6.6E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 118 244 1.3E-37 T 06-07-2017 IPR000014 PAS domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Gene3D G3DSA:3.30.450.20 116 235 6.9E-27 T 06-07-2017 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 2.0E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 2.0E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 478 2.0E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 2.0E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Pfam PF00989 PAS fold 122 233 8.7E-20 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Gene3D G3DSA:3.30.565.10 336 477 8.2E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS16750 a9c1aacacbc87c843c2333e29b35b2e6 488 Gene3D G3DSA:1.20.120.620 7 72 8.6E-4 T 06-07-2017 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 481 514 0.061 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 374 407 11.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 306 339 94.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 340 373 79.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 446 480 230.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 412 445 6.4E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 41 74 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 515 548 380.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SMART SM00028 272 305 12.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Pfam PF13414 TPR repeat 490 529 7.1E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Pfam PF13432 Tetratricopeptide repeat 424 480 0.0085 T 06-07-2017 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Pfam PF13432 Tetratricopeptide repeat 45 103 0.0015 T 06-07-2017 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SUPERFAMILY SSF48452 181 416 1.73E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SUPERFAMILY SSF48452 47 112 1.73E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 SUPERFAMILY SSF48452 371 547 3.53E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Pfam PF13174 Tetratricopeptide repeat 308 337 0.19 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Gene3D G3DSA:1.25.40.10 45 244 9.8E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS11155 1fa96c02cada22785c541623df1d176a 580 Gene3D G3DSA:1.25.40.10 271 550 3.9E-54 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS02355 3cae43a8cd414e73c35b92b4e75c8113 101 Pfam PF04956 TrbC/VIRB2 family 3 91 4.9E-25 T 06-07-2017 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 CAK95_RS05460 df56deaf33d1c28fe2da9806a959b63a 217 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 206 7.1E-37 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS05460 df56deaf33d1c28fe2da9806a959b63a 217 Pfam PF01914 MarC family integral membrane protein 7 211 2.6E-42 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK95_RS21650 1c0f9d969f596620e218a407c8810c67 130 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 122 7.9E-21 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS21650 1c0f9d969f596620e218a407c8810c67 130 SUPERFAMILY SSF69118 1 129 1.7E-37 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS21650 1c0f9d969f596620e218a407c8810c67 130 Gene3D G3DSA:1.20.1290.10 2 129 1.2E-39 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS21650 1c0f9d969f596620e218a407c8810c67 130 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 107 3.7E-19 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 Gene3D G3DSA:1.20.58.410 6 92 9.4E-9 T 06-07-2017 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 Gene3D G3DSA:3.30.160.20 209 283 1.6E-33 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 SUPERFAMILY SSF75620 10 351 5.76E-123 T 06-07-2017 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 356 38.232 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 Pfam PF03462 PCRF domain 12 202 2.8E-64 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 355 5.3E-143 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 Pfam PF00472 RF-1 domain 210 319 6.0E-42 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS10385 14683956a83a691776ea36505c9318f8 360 SMART SM00937 62 177 3.2E-54 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK95_RS14905 8931f09ab91d4f7814e2c5da0e377503 324 Gene3D G3DSA:3.90.850.10 79 322 9.7E-65 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS14905 8931f09ab91d4f7814e2c5da0e377503 324 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 128 320 1.5E-59 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS14905 8931f09ab91d4f7814e2c5da0e377503 324 SUPERFAMILY SSF56529 124 321 5.23E-63 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS09410 c8cb4148fd9004b459c0a8264b4b2120 307 SUPERFAMILY SSF53659 22 301 2.71E-66 T 06-07-2017 CAK95_RS09410 c8cb4148fd9004b459c0a8264b4b2120 307 Gene3D G3DSA:3.40.50.10750 120 274 3.6E-45 T 06-07-2017 CAK95_RS09410 c8cb4148fd9004b459c0a8264b4b2120 307 PIRSF PIRSF000428 12 304 2.1E-77 T 06-07-2017 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK95_RS09410 c8cb4148fd9004b459c0a8264b4b2120 307 Pfam PF01515 Phosphate acetyl/butaryl transferase 82 297 4.9E-44 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK95_RS04900 cbbf79a2027c806a4342d9e5148f6c39 376 SUPERFAMILY SSF53850 47 278 2.65E-35 T 06-07-2017 CAK95_RS04900 cbbf79a2027c806a4342d9e5148f6c39 376 Gene3D G3DSA:3.40.190.10 128 210 1.5E-13 T 06-07-2017 CAK95_RS04900 cbbf79a2027c806a4342d9e5148f6c39 376 Pfam PF09084 NMT1/THI5 like 62 269 3.4E-44 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 3.7E-35 T 06-07-2017 IPR011900 Glutaredoxin, GrxC GO:0045454 CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 Gene3D G3DSA:3.40.30.10 1 73 7.2E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 06-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 PRINTS PR00160 Glutaredoxin signature 47 60 1.1E-15 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 PRINTS PR00160 Glutaredoxin signature 4 22 1.1E-15 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 PRINTS PR00160 Glutaredoxin signature 61 74 1.1E-15 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 SUPERFAMILY SSF52833 1 87 2.87E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10435 8f7dd16a58c10ed6694ba388606fb9d2 90 Pfam PF00462 Glutaredoxin 4 64 5.9E-19 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 SUPERFAMILY SSF47616 77 196 3.14E-28 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 75 9.1E-15 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 SUPERFAMILY SSF52833 1 79 1.52E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 111 194 4.4E-10 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 Gene3D G3DSA:1.20.1050.10 91 199 3.3E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS16390 de6837867f590d36bb5a4e5955d7b011 211 Gene3D G3DSA:3.40.30.10 1 90 7.9E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10615 d7c9ccfd37b801c1848d191ff9eef809 368 Gene3D G3DSA:3.10.310.10 3 180 8.1E-79 T 06-07-2017 CAK95_RS10615 d7c9ccfd37b801c1848d191ff9eef809 368 SUPERFAMILY SSF54506 3 172 7.06E-66 T 06-07-2017 CAK95_RS10615 d7c9ccfd37b801c1848d191ff9eef809 368 SUPERFAMILY SSF54506 175 354 1.15E-56 T 06-07-2017 CAK95_RS10615 d7c9ccfd37b801c1848d191ff9eef809 368 Gene3D G3DSA:3.10.310.10 181 332 1.0E-51 T 06-07-2017 CAK95_RS10615 d7c9ccfd37b801c1848d191ff9eef809 368 Pfam PF04303 PrpF protein 7 352 2.4E-135 T 06-07-2017 IPR007400 PrpF protein CAK95_RS25505 74083b3d82c88e03481d8c015c1414a9 365 PIRSF PIRSF039026 1 357 2.5E-116 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAK95_RS25505 74083b3d82c88e03481d8c015c1414a9 365 SUPERFAMILY SSF53850 156 222 2.17E-5 T 06-07-2017 CAK95_RS25505 74083b3d82c88e03481d8c015c1414a9 365 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 322 5.8E-53 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS04240 644796a31bf92cb8a66739945dcd4740 269 SUPERFAMILY SSF55961 7 142 1.28E-26 T 06-07-2017 CAK95_RS04240 644796a31bf92cb8a66739945dcd4740 269 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 141 1.6E-9 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS04240 644796a31bf92cb8a66739945dcd4740 269 Gene3D G3DSA:3.30.530.20 9 146 1.8E-24 T 06-07-2017 IPR023393 START-like domain CAK95_RS00165 d2ee8b1d1e0e6496f0efc8efc469cd6c 250 SUPERFAMILY SSF52096 2 250 1.38E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS00165 d2ee8b1d1e0e6496f0efc8efc469cd6c 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 249 1.5E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS00165 d2ee8b1d1e0e6496f0efc8efc469cd6c 250 Gene3D G3DSA:3.90.226.10 2 250 3.0E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06110 4dd75274f45688d8d3feb0320356c048 369 SUPERFAMILY SSF51726 10 367 1.7E-78 T 06-07-2017 CAK95_RS06110 4dd75274f45688d8d3feb0320356c048 369 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 13 363 2.4E-16 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS06110 4dd75274f45688d8d3feb0320356c048 369 Gene3D G3DSA:3.20.20.210 6 368 1.4E-111 T 06-07-2017 CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 216 5.8E-71 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 PIRSF PIRSF003107 2 222 5.0E-64 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 Pfam PF01895 PhoU domain 21 108 1.8E-21 T 06-07-2017 IPR026022 PhoU domain CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 Pfam PF01895 PhoU domain 125 208 7.8E-20 T 06-07-2017 IPR026022 PhoU domain CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 Gene3D G3DSA:1.20.58.220 119 224 1.4E-33 T 06-07-2017 CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 Gene3D G3DSA:1.20.58.220 3 111 1.6E-31 T 06-07-2017 CAK95_RS05870 36b294fccab9712e78c76a02ec93babf 237 SUPERFAMILY SSF109755 7 228 4.71E-71 T 06-07-2017 CAK95_RS14175 a264597573aa6fc93f355c010a6afae9 161 Gene3D G3DSA:1.10.150.120 79 158 4.6E-35 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS14175 a264597573aa6fc93f355c010a6afae9 161 SUPERFAMILY SSF47741 88 157 1.83E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS14175 a264597573aa6fc93f355c010a6afae9 161 SUPERFAMILY SSF54292 6 81 2.04E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS14175 a264597573aa6fc93f355c010a6afae9 161 Gene3D G3DSA:3.10.20.30 5 78 4.1E-23 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS14175 a264597573aa6fc93f355c010a6afae9 161 Pfam PF01799 [2Fe-2S] binding domain 77 150 3.5E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS20580 09dc5ff7fcfd982d7c5a91257ca3a5ac 345 SUPERFAMILY SSF53850 131 301 1.99E-12 T 06-07-2017 CAK95_RS20580 09dc5ff7fcfd982d7c5a91257ca3a5ac 345 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 338 1.5E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20580 09dc5ff7fcfd982d7c5a91257ca3a5ac 345 PIRSF PIRSF017082 7 341 7.9E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 6.2E-25 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 Gene3D G3DSA:3.30.360.10 141 275 1.1E-25 T 06-07-2017 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 Gene3D G3DSA:3.30.360.10 337 389 1.1E-25 T 06-07-2017 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 SUPERFAMILY SSF51735 2 152 7.3E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 228 7.6E-8 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 SUPERFAMILY SSF55347 132 240 1.8E-18 T 06-07-2017 CAK95_RS05920 ffc36a3069f526a54149278ec38e5cb6 398 Gene3D G3DSA:3.40.50.720 1 140 3.1E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06605 20ff4f3788d543ee17d93df73a15c93a 139 Pfam PF01230 HIT domain 15 102 1.0E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS06605 20ff4f3788d543ee17d93df73a15c93a 139 PIRSF PIRSF000714 5 139 1.1E-47 T 06-07-2017 IPR026026 Histidine triad hydrolase, Hint-type CAK95_RS06605 20ff4f3788d543ee17d93df73a15c93a 139 Gene3D G3DSA:3.30.428.10 9 136 8.6E-32 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS06605 20ff4f3788d543ee17d93df73a15c93a 139 SUPERFAMILY SSF54197 12 136 5.78E-31 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS07735 034dd8fccc4e12c467882137eaac7a97 245 Pfam PF04250 Protein of unknown function (DUF429) 10 232 3.7E-54 T 06-07-2017 IPR007362 Protein of unknown function DUF429 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 Pfam PF04055 Radical SAM superfamily 147 317 4.2E-23 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 SMART SM00729 142 360 1.4E-55 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 Gene3D G3DSA:3.80.30.20 142 369 1.6E-65 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 Pfam PF00919 Uncharacterized protein family UPF0004 3 89 6.4E-19 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 1.2E-105 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 5 412 1.3E-134 T 06-07-2017 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CAK95_RS07615 ed469c47099ac6a36dcc4078ca74be7c 423 SUPERFAMILY SSF102114 123 361 4.97E-54 T 06-07-2017 CAK95_RS10550 895e035f472913ea512d296a92bac4cc 260 Pfam PF11306 Protein of unknown function (DUF3108) 3 246 2.6E-35 T 06-07-2017 IPR021457 Protein of unknown function DUF3108 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 SUPERFAMILY SSF56655 7 259 5.1E-60 T 06-07-2017 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 Pfam PF00459 Inositol monophosphatase family 13 259 4.4E-39 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 8.3E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 8.3E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 227 8.3E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 8.3E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 Gene3D G3DSA:3.40.190.80 178 262 4.0E-20 T 06-07-2017 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 206 220 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAK95_RS13420 804cab3a5ce62f112db1719accbe4150 265 Gene3D G3DSA:3.30.540.10 6 155 6.6E-38 T 06-07-2017 CAK95_RS14040 ae4c512d0021c4ea2a1debededa06873 90 Pfam PF11391 Protein of unknown function (DUF2798) 24 81 5.7E-19 T 06-07-2017 IPR021529 Protein of unknown function DUF2798 CAK95_RS26760 f8bd654b29eb5b0727b3194da90b47fd 595 Gene3D G3DSA:1.50.10.10 211 586 1.5E-81 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK95_RS26760 f8bd654b29eb5b0727b3194da90b47fd 595 Pfam PF00723 Glycosyl hydrolases family 15 215 525 2.4E-52 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK95_RS26760 f8bd654b29eb5b0727b3194da90b47fd 595 Pfam PF00723 Glycosyl hydrolases family 15 530 578 4.2E-5 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK95_RS26760 f8bd654b29eb5b0727b3194da90b47fd 595 SUPERFAMILY SSF48208 187 583 2.93E-104 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK95_RS25935 0f81381cca79ad6d88ea606828801c3b 418 PIRSF PIRSF003085 2 403 1.0E-134 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK95_RS25935 0f81381cca79ad6d88ea606828801c3b 418 Pfam PF02353 Mycolic acid cyclopropane synthetase 114 379 5.5E-92 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25935 0f81381cca79ad6d88ea606828801c3b 418 SUPERFAMILY SSF53335 123 383 1.48E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25935 0f81381cca79ad6d88ea606828801c3b 418 Gene3D G3DSA:3.40.50.150 112 382 1.3E-94 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS21405 7e2d19a1eb2d6f3e51bee20d663da4a7 124 Pfam PF01638 HxlR-like helix-turn-helix 20 109 1.1E-33 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS21405 7e2d19a1eb2d6f3e51bee20d663da4a7 124 Gene3D G3DSA:1.10.10.10 6 112 1.9E-43 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21405 7e2d19a1eb2d6f3e51bee20d663da4a7 124 SUPERFAMILY SSF46785 10 110 9.1E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 Pfam PF01546 Peptidase family M20/M25/M40 83 413 1.8E-27 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 Gene3D G3DSA:3.30.70.360 232 331 3.0E-34 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 SUPERFAMILY SSF53187 343 416 6.0E-70 T 06-07-2017 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 SUPERFAMILY SSF53187 16 229 6.0E-70 T 06-07-2017 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 SUPERFAMILY SSF55031 219 331 3.29E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 Pfam PF07687 Peptidase dimerisation domain 219 318 5.0E-8 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 21 406 6.7E-106 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 Gene3D G3DSA:3.40.630.10 16 231 4.4E-91 T 06-07-2017 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 Gene3D G3DSA:3.40.630.10 358 417 4.4E-91 T 06-07-2017 CAK95_RS23530 4fbe60d0f4ae6f78a45a5acf1bb2472c 421 PIRSF PIRSF001235 12 420 3.7E-121 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS08805 bae6fc7e856ecc03d7004219ecae16b7 177 Gene3D G3DSA:1.10.287.1080 75 153 4.8E-4 T 06-07-2017 CAK95_RS08805 bae6fc7e856ecc03d7004219ecae16b7 177 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 77 160 1.1E-14 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CAK95_RS08805 bae6fc7e856ecc03d7004219ecae16b7 177 SUPERFAMILY SSF101386 75 164 3.74E-22 T 06-07-2017 CAK95_RS08805 bae6fc7e856ecc03d7004219ecae16b7 177 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 76 159 2.8E-28 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK95_RS08805 bae6fc7e856ecc03d7004219ecae16b7 177 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 73 159 19.452 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 SUPERFAMILY SSF53659 3 365 5.22E-113 T 06-07-2017 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 SMART SM01329 5 361 6.6E-178 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 365 47.38 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 360 3.5E-135 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 361 1.3E-130 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 Gene3D G3DSA:3.40.718.10 2 366 1.2E-120 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS07790 a4c4d06d3a4ad1fdbeb32bf02c4d843c 370 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 Gene3D G3DSA:3.40.50.720 1 156 5.3E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 SUPERFAMILY SSF51735 1 156 1.16E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 SUPERFAMILY SSF48179 159 287 7.29E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 156 3.8E-44 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 279 3.3E-20 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 PIRSF PIRSF000103 1 289 4.3E-72 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS12685 bd41692c5b75d5fbcf36642cafa1d6f7 289 Gene3D G3DSA:1.10.1040.10 161 284 2.6E-26 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 Gene3D G3DSA:3.40.50.620 1 119 2.1E-14 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 SUPERFAMILY SSF52402 156 277 3.68E-19 T 06-07-2017 CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 Pfam PF00582 Universal stress protein family 1 117 7.8E-6 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 Pfam PF00582 Universal stress protein family 157 276 1.7E-8 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 SUPERFAMILY SSF52402 1 150 1.0E-14 T 06-07-2017 CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 Gene3D G3DSA:3.40.50.620 142 277 3.5E-16 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 PRINTS PR01438 Universal stress protein signature 237 249 3.4E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 PRINTS PR01438 Universal stress protein signature 255 277 3.4E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS06475 cb9c8d03faeaa31acfe42a721c1ad214 277 PRINTS PR01438 Universal stress protein signature 155 173 3.4E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK95_RS11500 926bb81231095f0239988d20e5445863 337 SMART SM00829 10 334 2.7E-25 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS11500 926bb81231095f0239988d20e5445863 337 Gene3D G3DSA:3.90.180.10 1 164 1.1E-40 T 06-07-2017 IPR011032 GroES-like CAK95_RS11500 926bb81231095f0239988d20e5445863 337 SUPERFAMILY SSF51735 137 311 1.06E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11500 926bb81231095f0239988d20e5445863 337 SUPERFAMILY SSF50129 1 165 2.28E-37 T 06-07-2017 IPR011032 GroES-like CAK95_RS11500 926bb81231095f0239988d20e5445863 337 Pfam PF00107 Zinc-binding dehydrogenase 171 298 4.7E-34 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS11500 926bb81231095f0239988d20e5445863 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 87 1.2E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS11500 926bb81231095f0239988d20e5445863 337 Gene3D G3DSA:3.40.50.720 165 283 9.1E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16100 72a252fef2ffe2c3a17f08c6c907d969 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 1.8E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16100 72a252fef2ffe2c3a17f08c6c907d969 337 PIRSF PIRSF017082 4 336 1.7E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16100 72a252fef2ffe2c3a17f08c6c907d969 337 SUPERFAMILY SSF53850 129 296 1.09E-7 T 06-07-2017 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 412 1.2E-105 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 78 87 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 Gene3D G3DSA:3.30.70.360 226 329 6.7E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 SUPERFAMILY SSF53187 341 415 4.1E-81 T 06-07-2017 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 SUPERFAMILY SSF53187 4 223 4.1E-81 T 06-07-2017 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 Gene3D G3DSA:3.40.630.10 356 416 3.2E-97 T 06-07-2017 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 Gene3D G3DSA:3.40.630.10 3 225 3.2E-97 T 06-07-2017 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 Pfam PF01546 Peptidase family M20/M25/M40 79 411 2.4E-33 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 PIRSF PIRSF001235 5 417 9.0E-124 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS01185 23ce66b2d99892423298544eacdae76f 423 SUPERFAMILY SSF55031 213 321 8.02E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 Gene3D G3DSA:3.40.50.1820 2 230 2.1E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 Pfam PF00561 alpha/beta hydrolase fold 21 121 1.6E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20700 3ef4f64853993838b2072695626440bf 250 SUPERFAMILY SSF53474 2 231 9.59E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 Pfam PF00696 Amino acid kinase family 8 216 2.1E-30 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 SUPERFAMILY SSF53633 6 236 4.45E-64 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 Gene3D G3DSA:3.40.1160.10 3 236 1.1E-75 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 236 3.2E-87 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 39.156 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAK95_RS22965 887ab0ec121e1eb51f5cc54f75eaa6ec 238 PIRSF PIRSF005650 1 238 1.8E-82 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 173 235 1.2E-7 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 9.9E-29 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 Gene3D G3DSA:1.10.287.1080 24 76 1.2E-8 T 06-07-2017 CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 Gene3D G3DSA:1.10.287.1080 144 227 9.4E-14 T 06-07-2017 CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 TIGRFAM TIGR00444 mazG: MazG family protein 13 266 5.0E-92 T 06-07-2017 IPR011551 NTP pyrophosphohydrolase MazG CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 SUPERFAMILY SSF101386 5 106 3.74E-25 T 06-07-2017 CAK95_RS23285 d185bb074290bbae2c50425f109c5fb9 290 SUPERFAMILY SSF101386 147 242 3.74E-24 T 06-07-2017 CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 SMART SM00530 49 104 3.1E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 Gene3D G3DSA:2.60.120.10 99 218 3.7E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 SUPERFAMILY SSF47413 41 109 1.07E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 Pfam PF07883 Cupin domain 152 217 1.1E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 SUPERFAMILY SSF51182 89 218 9.25E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 Gene3D G3DSA:1.10.260.40 43 98 3.2E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27810 16aaa07e2ea248ce88f1a9452d4ab3fa 222 Pfam PF01381 Helix-turn-helix 50 104 2.8E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 Gene3D G3DSA:3.40.50.2300 19 149 5.7E-34 T 06-07-2017 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 Gene3D G3DSA:3.40.50.2300 288 356 5.7E-34 T 06-07-2017 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 Gene3D G3DSA:3.40.50.2300 150 251 1.0E-7 T 06-07-2017 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 Pfam PF13458 Periplasmic binding protein 26 369 4.3E-49 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 SUPERFAMILY SSF53822 26 370 2.83E-51 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 3.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 3.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 66 84 3.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS16020 2a01459293472f1df1da9b82f5a621a2 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 3.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS24740 ea5b97dae14f1a9f58c6d8e7b0a50afa 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 253 8.7E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24740 ea5b97dae14f1a9f58c6d8e7b0a50afa 256 Gene3D G3DSA:1.10.3720.10 58 253 4.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24740 ea5b97dae14f1a9f58c6d8e7b0a50afa 256 SUPERFAMILY SSF161098 20 249 1.7E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 SUPERFAMILY SSF161098 251 369 1.24E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 SUPERFAMILY SSF161098 79 146 1.24E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 382 6.0E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 Gene3D G3DSA:1.10.3720.10 251 381 1.8E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 Gene3D G3DSA:1.10.3720.10 78 146 1.8E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01235 5be80b83141ff9b43845bb1ccd574de5 387 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 78 143 6.9E-14 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS11480 96e308582c0736308d0e141ecb4a1e1c 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 66 1.0E-5 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAK95_RS11480 96e308582c0736308d0e141ecb4a1e1c 297 Gene3D G3DSA:1.10.3720.10 82 293 1.7E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11480 96e308582c0736308d0e141ecb4a1e1c 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 296 3.4E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11480 96e308582c0736308d0e141ecb4a1e1c 297 SUPERFAMILY SSF161098 84 268 5.89E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26340 a8f182c672d2c32351c4cb1d94d4b641 382 Pfam PF02541 Ppx/GppA phosphatase family 72 370 2.5E-41 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAK95_RS26340 a8f182c672d2c32351c4cb1d94d4b641 382 Gene3D G3DSA:3.30.420.40 57 175 9.3E-40 T 06-07-2017 CAK95_RS26340 a8f182c672d2c32351c4cb1d94d4b641 382 Gene3D G3DSA:3.30.420.150 179 372 2.1E-51 T 06-07-2017 CAK95_RS26340 a8f182c672d2c32351c4cb1d94d4b641 382 SUPERFAMILY SSF53067 183 371 1.09E-36 T 06-07-2017 CAK95_RS26340 a8f182c672d2c32351c4cb1d94d4b641 382 SUPERFAMILY SSF53067 58 178 2.51E-33 T 06-07-2017 CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 3 117 1.5E-27 T 06-07-2017 IPR017560 Cytochrome c-type biogenesis protein CcmI CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 Pfam PF13432 Tetratricopeptide repeat 209 259 1.6E-6 T 06-07-2017 CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 SUPERFAMILY SSF48452 143 262 1.52E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 SUPERFAMILY SSF48452 314 357 1.52E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 Gene3D G3DSA:1.25.40.10 141 259 1.0E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS19160 a3da03972335bf398a8c023fc042d91a 382 Gene3D G3DSA:1.25.40.10 331 356 1.0E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 SUPERFAMILY SSF46785 52 124 1.77E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 Gene3D G3DSA:3.30.450.40 123 298 2.3E-40 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 SMART SM00346 52 142 1.0E-23 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 SUPERFAMILY SSF55781 119 298 7.85E-35 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 Pfam PF01614 Bacterial transcriptional regulator 172 295 4.5E-20 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 Pfam PF09339 IclR helix-turn-helix domain 54 103 1.0E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS13875 cd56f232a0c5c989f3b88743b4f8b8df 307 Gene3D G3DSA:1.10.10.10 45 122 1.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 SUPERFAMILY SSF54373 212 307 9.81E-36 T 06-07-2017 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 447 547 3.4E-47 T 06-07-2017 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 Reactome: R-HSA-611105 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 SUPERFAMILY SSF54862 451 550 6.39E-28 T 06-07-2017 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 SUPERFAMILY SSF51905 6 210 4.53E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 SUPERFAMILY SSF51905 307 449 4.53E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 Gene3D G3DSA:3.50.50.60 117 222 1.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 Gene3D G3DSA:3.50.50.60 12 50 1.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 Gene3D G3DSA:3.50.50.60 308 447 1.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 2.7E-5 T 06-07-2017 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 2.7E-5 T 06-07-2017 CAK95_RS11160 f114224006de077e1bc48077e141e5f1 550 Pfam PF13450 NAD(P)-binding Rossmann-like domain 16 57 1.2E-7 T 06-07-2017 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 Gene3D G3DSA:1.10.630.10 19 409 3.8E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 287 298 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 143 159 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 353 362 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 362 373 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 97 108 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 203 225 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 160 175 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 304 331 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 PRINTS PR00359 B-class P450 signature 332 347 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 Pfam PF00067 Cytochrome P450 190 383 4.4E-27 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS19990 64c11950cc90fbc4bf0e7a70caf52002 411 SUPERFAMILY SSF48264 23 407 9.69E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 9.1E-59 T 06-07-2017 CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 Gene3D G3DSA:3.40.50.720 2 251 1.5E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS15980 aadcd38ecf1560eb6b5a00141a145c2d 254 SUPERFAMILY SSF51735 6 251 1.5E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 335 38.39 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 12 333 1.5E-120 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 67 1.6E-18 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 Gene3D G3DSA:3.40.1030.10 75 337 7.4E-107 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 SUPERFAMILY SSF47648 7 72 1.3E-19 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 Gene3D G3DSA:1.20.970.10 8 71 2.9E-25 T 06-07-2017 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 SUPERFAMILY SSF52418 77 337 6.15E-93 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK95_RS23085 79f423935e5e02f590dd7842cf02635a 338 Pfam PF00591 Glycosyl transferase family, a/b domain 76 325 2.0E-93 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 Gene3D G3DSA:3.40.50.261 233 372 9.4E-37 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 Pfam PF08442 ATP-grasp domain 3 193 1.8E-49 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 Gene3D G3DSA:3.30.1490.20 23 87 7.8E-14 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 Pfam PF00549 CoA-ligase 254 345 6.7E-9 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 SUPERFAMILY SSF52210 231 374 5.89E-33 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 Gene3D G3DSA:3.30.470.20 88 220 2.6E-42 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 SUPERFAMILY SSF56059 3 220 1.04E-52 T 06-07-2017 CAK95_RS09400 04f343b5ff1af09096901c7a780c9b4e 375 PIRSF PIRSF001554 1 375 6.3E-113 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 SUPERFAMILY SSF53474 8 261 5.13E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 Pfam PF00561 alpha/beta hydrolase fold 28 129 6.3E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 3.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 3.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 3.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14030 e957575e672e29fbb060d9c411cf1704 272 Gene3D G3DSA:3.40.50.1820 8 263 7.6E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 Gene3D G3DSA:3.90.1150.10 249 360 1.0E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 SUPERFAMILY SSF53383 6 360 4.21E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 359 6.7E-85 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 361 55.648 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 Gene3D G3DSA:3.40.640.10 42 248 2.8E-59 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS12150 e3309e1bd6a9164fc3901c030b88e2cc 363 Pfam PF00155 Aminotransferase class I and II 29 355 6.8E-48 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 Pfam PF13458 Periplasmic binding protein 37 372 4.2E-64 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 355 370 7.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 7.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 7.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 7.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 Gene3D G3DSA:3.40.50.2300 36 237 6.2E-44 T 06-07-2017 CAK95_RS12695 8e2e83a7bb7a11287fc0722ea3c73140 424 SUPERFAMILY SSF53822 37 386 5.65E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 PIRSF PIRSF036758 16 414 2.3E-99 T 06-07-2017 IPR015840 DNA methyase, ParB domain-containing CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 Pfam PF01555 DNA methylase 203 391 8.1E-14 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 376 396 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 200 214 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 353 371 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 334 351 4.1E-12 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 Pfam PF02195 ParB-like nuclease domain 22 104 3.0E-13 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 SUPERFAMILY SSF53335 169 400 2.11E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 Gene3D G3DSA:3.90.1530.10 17 105 3.6E-18 T 06-07-2017 CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 SMART SM00470 19 105 4.3E-15 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 Gene3D G3DSA:3.40.50.150 177 398 9.8E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03435 eae2b1cc26dc31b9a391be02ef0d80d3 457 SUPERFAMILY SSF110849 17 126 1.92E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 PRINTS PR00986 Valyl-tRNA synthetase signature 234 251 8.0E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 PRINTS PR00986 Valyl-tRNA synthetase signature 366 379 8.0E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 8.0E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 PRINTS PR00986 Valyl-tRNA synthetase signature 487 508 8.0E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 PRINTS PR00986 Valyl-tRNA synthetase signature 518 536 8.0E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 606 7.9E-207 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 SUPERFAMILY SSF46589 872 936 9.94E-16 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Gene3D G3DSA:3.90.740.10 197 355 1.6E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Gene3D G3DSA:3.40.50.620 4 196 3.6E-144 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Gene3D G3DSA:3.40.50.620 361 604 3.6E-144 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 937 15.793 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 872 937 2.8E-19 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Pfam PF08264 Anticodon-binding domain of tRNA 648 810 1.1E-35 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 SUPERFAMILY SSF47323 619 886 2.99E-54 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Gene3D G3DSA:1.10.730.10 606 806 2.6E-64 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 Gene3D G3DSA:1.10.287.380 865 936 5.4E-7 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 SUPERFAMILY SSF52374 361 616 1.21E-136 T 06-07-2017 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 SUPERFAMILY SSF52374 3 195 1.21E-136 T 06-07-2017 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 919 0.0 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK95_RS24070 20fdda867b038b80f0c623cbe393aedc 940 SUPERFAMILY SSF50677 195 362 5.89E-54 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 PIRSF PIRSF004486 14 318 3.8E-99 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 SUPERFAMILY SSF81799 124 222 7.59E-32 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 16 316 6.5E-91 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 Gene3D G3DSA:3.40.50.150 17 120 1.9E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 Gene3D G3DSA:3.40.50.150 225 317 1.9E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 Gene3D G3DSA:1.10.150.170 122 224 5.2E-33 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 SUPERFAMILY SSF53335 222 316 2.16E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 SUPERFAMILY SSF53335 17 123 2.16E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 Pfam PF01795 MraW methylase family 16 316 2.5E-96 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13575 ab44fd0e0c0157894ebfe24ceb231a47 344 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 17 317 36.633 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS18655 54f4a6cc9c44510a99ef0f4950b1ab7e 402 SUPERFAMILY SSF53822 24 400 2.76E-82 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS18655 54f4a6cc9c44510a99ef0f4950b1ab7e 402 Gene3D G3DSA:3.40.50.2300 152 323 6.0E-37 T 06-07-2017 CAK95_RS18655 54f4a6cc9c44510a99ef0f4950b1ab7e 402 Pfam PF13458 Periplasmic binding protein 24 366 1.2E-81 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS00310 9fbbd95118fcbc5eb99f163cf33b0acd 333 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 307 9.1E-50 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 570 1.4E-291 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 ProSitePatterns PS00145 Urease active site. 319 335 - T 06-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Gene3D G3DSA:2.30.40.10 70 145 4.2E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Pfam PF01979 Amidohydrolase family 127 453 8.3E-76 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 SUPERFAMILY SSF51556 483 570 9.4E-198 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS17335 3e549608337c597c72c713377caa8403 570 SUPERFAMILY SSF51556 131 434 9.4E-198 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS17335 3e549608337c597c72c713377caa8403 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 297 314 8.7E-35 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 336 352 8.7E-35 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 8.7E-35 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 8.7E-35 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 121 3.0E-55 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Hamap MF_01953 Urease subunit alpha [ureC]. 3 570 55.949 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 SUPERFAMILY SSF51338 424 479 2.59E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Gene3D G3DSA:3.20.20.140 490 568 4.0E-210 T 06-07-2017 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 Gene3D G3DSA:3.20.20.140 146 431 4.0E-210 T 06-07-2017 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 SUPERFAMILY SSF51338 3 179 5.04E-63 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS17335 3e549608337c597c72c713377caa8403 570 ProSitePatterns PS01120 Urease nickel ligands signature. 129 142 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 Gene3D G3DSA:3.40.50.1820 40 217 4.5E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 Gene3D G3DSA:3.40.50.1820 250 385 4.5E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 31 383 7.4E-148 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 PIRSF PIRSF000443 9 391 2.3E-141 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 SUPERFAMILY SSF53474 32 384 3.82E-101 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 16 385 47.885 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK95_RS12160 0050efb49ce371606665887b7135feeb 396 Pfam PF00561 alpha/beta hydrolase fold 61 371 4.1E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 SMART SM00382 32 231 2.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 Pfam PF00005 ABC transporter 23 181 4.3E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 Gene3D G3DSA:3.40.50.300 3 255 9.6E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 5.6E-23 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 SUPERFAMILY SSF52540 4 252 8.65E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26690 fbdbe3d2e07e51f39da3320f078a8d23 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 3.7E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS22590 ab264d113e2992a74f95e9cc24e1dff6 381 Pfam PF13579 Glycosyl transferase 4-like domain 19 184 1.9E-20 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS22590 ab264d113e2992a74f95e9cc24e1dff6 381 SUPERFAMILY SSF53756 12 374 8.07E-62 T 06-07-2017 CAK95_RS22590 ab264d113e2992a74f95e9cc24e1dff6 381 Pfam PF00534 Glycosyl transferases group 1 187 342 2.5E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS22590 ab264d113e2992a74f95e9cc24e1dff6 381 Gene3D G3DSA:3.40.50.2000 193 343 2.8E-23 T 06-07-2017 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Gene3D G3DSA:3.40.50.300 152 334 4.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 4.0E-46 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Pfam PF06480 FtsH Extracellular 10 96 2.0E-10 T 06-07-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Pfam PF01434 Peptidase family M41 386 596 1.2E-78 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 104 597 3.1E-237 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 SUPERFAMILY SSF52540 153 421 4.33E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Gene3D G3DSA:1.10.8.60 335 400 4.2E-30 T 06-07-2017 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 SMART SM00382 188 327 7.1E-26 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 611 37.596 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAK95_RS03965 d0c4195c6717be3db68a9cac31e1c203 640 SUPERFAMILY SSF140990 406 603 5.75E-73 T 06-07-2017 CAK95_RS10275 2fd5dc3709f826adefe00369d1d43a07 306 SUPERFAMILY SSF103481 56 154 2.48E-12 T 06-07-2017 CAK95_RS10275 2fd5dc3709f826adefe00369d1d43a07 306 Pfam PF00892 EamA-like transporter family 26 153 2.7E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS10275 2fd5dc3709f826adefe00369d1d43a07 306 Pfam PF00892 EamA-like transporter family 167 303 1.4E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS10275 2fd5dc3709f826adefe00369d1d43a07 306 SUPERFAMILY SSF103481 207 305 1.44E-9 T 06-07-2017 CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 Pfam PF09339 IclR helix-turn-helix domain 10 61 5.8E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 Gene3D G3DSA:3.30.450.40 76 248 2.3E-36 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 SUPERFAMILY SSF46785 8 81 1.02E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 SUPERFAMILY SSF55781 74 248 7.85E-34 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 Pfam PF01614 Bacterial transcriptional regulator 137 243 4.2E-13 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 SMART SM00346 8 98 4.0E-21 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS04465 4917d8ba5565e67fddfbf8d4bc117a4a 249 Gene3D G3DSA:1.10.10.10 5 75 2.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Pfam PF14579 Helix-hairpin-helix motif 794 885 2.5E-21 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Pfam PF01336 OB-fold nucleic acid binding domain 988 1060 2.1E-6 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 SMART SM00481 5 81 6.1E-7 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 284 720 1.3E-141 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 SUPERFAMILY SSF89550 143 208 8.44E-5 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 SUPERFAMILY SSF89550 11 91 8.44E-5 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Gene3D G3DSA:3.20.20.140 11 249 9.2E-9 T 06-07-2017 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Pfam PF02811 PHP domain 7 105 1.3E-6 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 4 1098 13.572 T 06-07-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS19240 22ddef90a80fe0b74e756189144bda01 1098 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1022 3.1E-152 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 Pfam PF13847 Methyltransferase domain 154 251 1.6E-8 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 SMART SM00028 53 86 0.013 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 SMART SM00028 19 52 0.011 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 Gene3D G3DSA:1.25.40.10 22 87 9.3E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 SUPERFAMILY SSF48452 19 87 1.73E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 SUPERFAMILY SSF53335 106 294 6.63E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 Pfam PF13432 Tetratricopeptide repeat 23 86 3.0E-10 T 06-07-2017 CAK95_RS05645 6d340b7d74a387e48d1d018e204000f4 321 Gene3D G3DSA:3.40.50.150 105 290 3.1E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17195 9700894a2b72e5d1bcae7356b57c89ef 270 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 190 1.2E-29 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS17195 9700894a2b72e5d1bcae7356b57c89ef 270 Gene3D G3DSA:3.40.225.10 3 211 2.4E-42 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS17195 9700894a2b72e5d1bcae7356b57c89ef 270 SMART SM01007 7 191 1.6E-21 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS17195 9700894a2b72e5d1bcae7356b57c89ef 270 SUPERFAMILY SSF53639 2 209 4.32E-36 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 SUPERFAMILY SSF52091 394 483 3.53E-10 T 06-07-2017 IPR002645 STAS domain CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 Gene3D G3DSA:3.30.750.24 397 482 3.6E-6 T 06-07-2017 IPR002645 STAS domain CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 Pfam PF00916 Sulfate permease family 145 343 7.0E-28 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 Pfam PF00916 Sulfate permease family 15 144 4.0E-27 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 06-07-2017 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 CAK95_RS10900 7a29a5a82b2390e99a5dcf613c697e8f 493 Pfam PF01740 STAS domain 402 484 2.0E-6 T 06-07-2017 IPR002645 STAS domain CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 SUPERFAMILY SSF53850 90 295 9.23E-35 T 06-07-2017 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 SUPERFAMILY SSF46785 7 109 6.95E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 Pfam PF03466 LysR substrate binding domain 89 289 4.2E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 Gene3D G3DSA:1.10.10.10 6 85 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 Gene3D G3DSA:3.40.190.10 92 175 6.9E-19 T 06-07-2017 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 7.1E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS24005 cb247c5972e770e54d3a5dc595af7eb1 335 Gene3D G3DSA:3.40.190.10 176 261 1.6E-15 T 06-07-2017 CAK95_RS13475 850a4349ebf0afb0b2d78bf6786e7d13 153 Pfam PF01575 MaoC like domain 11 115 1.2E-14 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS13475 850a4349ebf0afb0b2d78bf6786e7d13 153 Gene3D G3DSA:3.10.129.10 3 147 2.3E-37 T 06-07-2017 IPR029069 HotDog domain CAK95_RS13475 850a4349ebf0afb0b2d78bf6786e7d13 153 SUPERFAMILY SSF54637 3 148 6.34E-37 T 06-07-2017 IPR029069 HotDog domain CAK95_RS22740 cada4e0152527314b459a01c8d45dcb2 327 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 102 309 2.9E-99 T 06-07-2017 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 CAK95_RS22740 cada4e0152527314b459a01c8d45dcb2 327 Pfam PF01618 MotA/TolQ/ExbB proton channel family 169 290 9.8E-35 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAK95_RS22610 8ed8fb4ba2a1ac5f95052a6c06a05063 69 Pfam PF11003 Protein of unknown function (DUF2842) 6 65 5.4E-21 T 06-07-2017 IPR021265 Protein of unknown function DUF2842 CAK95_RS26660 161252ad46fbcb664cb13436d8d60cbc 732 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 37 230 9.4E-52 T 06-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal CAK95_RS26660 161252ad46fbcb664cb13436d8d60cbc 732 Pfam PF06202 Amylo-alpha-1,6-glucosidase 290 656 1.6E-12 T 06-07-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK95_RS26660 161252ad46fbcb664cb13436d8d60cbc 732 SUPERFAMILY SSF48208 260 713 5.39E-90 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK95_RS18505 4d3109f05c47b8edc4a61d6bd7ce3846 212 Pfam PF06532 Protein of unknown function (DUF1109) 10 212 1.5E-53 T 06-07-2017 IPR009495 Protein of unknown function DUF1109 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 Gene3D G3DSA:1.20.120.140 45 133 3.7E-20 T 06-07-2017 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 SMART SM00962 152 353 2.6E-112 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 Gene3D G3DSA:3.40.50.300 148 353 5.2E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 83 351 4.7E-99 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 SUPERFAMILY SSF52540 150 352 6.23E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 SMART SM00382 151 331 1.5E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 82 353 58.521 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 Pfam PF00448 SRP54-type protein, GTPase domain 152 351 5.2E-73 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 326 339 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 SUPERFAMILY SSF47364 54 129 8.9E-18 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 SMART SM00963 59 138 6.5E-11 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS07600 ec66af4547e9e922083f647b0993b57a 356 Pfam PF02881 SRP54-type protein, helical bundle domain 69 132 1.4E-8 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK95_RS04850 c047eb5d4bb6bbd5f8ea2b82861171c7 69 Gene3D G3DSA:1.10.260.40 2 67 6.9E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS04850 c047eb5d4bb6bbd5f8ea2b82861171c7 69 Pfam PF01381 Helix-turn-helix 12 65 1.2E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS04850 c047eb5d4bb6bbd5f8ea2b82861171c7 69 SMART SM00530 11 66 8.2E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS04850 c047eb5d4bb6bbd5f8ea2b82861171c7 69 SUPERFAMILY SSF47413 2 67 7.51E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02240 3e2264e8b60bcf84fd6fd23b8b0c26f6 285 Gene3D G3DSA:3.40.50.1820 33 268 8.3E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS02240 3e2264e8b60bcf84fd6fd23b8b0c26f6 285 SUPERFAMILY SSF53474 6 259 2.66E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS02240 3e2264e8b60bcf84fd6fd23b8b0c26f6 285 Pfam PF07859 alpha/beta hydrolase fold 69 181 1.5E-9 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 SUPERFAMILY SSF46689 249 296 2.69E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 Gene3D G3DSA:2.60.120.280 50 179 1.9E-9 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 Pfam PF12833 Helix-turn-helix domain 216 295 3.5E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 Gene3D G3DSA:1.10.10.60 193 245 6.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 Gene3D G3DSA:1.10.10.60 248 295 5.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 Pfam PF02311 AraC-like ligand binding domain 49 154 5.4E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 SMART SM00342 210 293 8.1E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS25350 d6838dd887a69a57318de2b275af29f6 299 SUPERFAMILY SSF51215 45 179 2.35E-13 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS10575 1577b261fac4b509726d3cde0fc46641 317 Pfam PF03781 Sulfatase-modifying factor enzyme 1 14 314 1.3E-89 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK95_RS10575 1577b261fac4b509726d3cde0fc46641 317 SUPERFAMILY SSF56436 14 315 8.48E-94 T 06-07-2017 IPR016187 C-type lectin fold CAK95_RS10575 1577b261fac4b509726d3cde0fc46641 317 Gene3D G3DSA:3.90.1580.10 8 315 1.1E-96 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK95_RS03190 17d57d12e867064d5af9fe0849d7754d 195 Pfam PF09343 Conserved hypothetical protein 2217 (DUF2460) 6 194 2.7E-58 T 06-07-2017 IPR011740 Protein of unknown function DUF2460 CAK95_RS03190 17d57d12e867064d5af9fe0849d7754d 195 TIGRFAM TIGR02217 chp_TIGR02217: TIGR02217 family protein 4 194 2.3E-57 T 06-07-2017 IPR011740 Protein of unknown function DUF2460 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 Gene3D G3DSA:3.50.50.60 126 211 5.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 Gene3D G3DSA:3.50.50.60 16 82 5.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 Gene3D G3DSA:3.50.50.60 306 388 5.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 SUPERFAMILY SSF51905 305 389 6.49E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 SUPERFAMILY SSF51905 17 206 6.49E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 333 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 185 200 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 351 369 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 369 385 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 6.0E-41 T 06-07-2017 CAK95_RS15770 7d696782528b435f293b548590381c9f 563 Pfam PF01494 FAD binding domain 16 380 2.8E-72 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS11410 c6f9678d281e074add98d07b858adaa7 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 244 1.0E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11410 c6f9678d281e074add98d07b858adaa7 269 Gene3D G3DSA:1.10.3720.10 70 245 5.1E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11410 c6f9678d281e074add98d07b858adaa7 269 SUPERFAMILY SSF161098 67 249 7.06E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 SUPERFAMILY SSF47240 7 162 2.63E-48 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 46 62 1.3E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 142 160 1.3E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 70 86 1.3E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 Gene3D G3DSA:1.20.1260.10 4 161 3.7E-58 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 Pfam PF00210 Ferritin-like domain 27 161 5.8E-31 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK95_RS21525 6045c7b97de4d530f18a6f930c53ca90 172 PIRSF PIRSF005900 3 169 2.4E-50 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK95_RS03130 a8d9fc3c23a05c65aaa2a315d5e28b87 129 Pfam PF02924 Bacteriophage lambda head decoration protein D 3 123 4.2E-35 T 06-07-2017 IPR004195 Head decoration protein D GO:0019028 CAK95_RS20155 27b5de26a5c570b540b3577f8fdd6d7d 414 Gene3D G3DSA:1.20.1250.20 16 189 4.1E-13 T 06-07-2017 CAK95_RS20155 27b5de26a5c570b540b3577f8fdd6d7d 414 Gene3D G3DSA:1.20.1250.20 209 389 6.0E-26 T 06-07-2017 CAK95_RS20155 27b5de26a5c570b540b3577f8fdd6d7d 414 SUPERFAMILY SSF103473 12 388 6.54E-45 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS20155 27b5de26a5c570b540b3577f8fdd6d7d 414 Pfam PF07690 Major Facilitator Superfamily 19 180 2.1E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS20155 27b5de26a5c570b540b3577f8fdd6d7d 414 Pfam PF07690 Major Facilitator Superfamily 210 390 9.0E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS13370 3e048b59295dc6beb3349015548e868b 361 Gene3D G3DSA:3.90.1200.10 123 266 1.2E-29 T 06-07-2017 CAK95_RS13370 3e048b59295dc6beb3349015548e868b 361 Pfam PF01636 Phosphotransferase enzyme family 44 268 1.2E-54 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK95_RS13370 3e048b59295dc6beb3349015548e868b 361 Gene3D G3DSA:3.30.200.20 41 104 2.2E-6 T 06-07-2017 CAK95_RS13370 3e048b59295dc6beb3349015548e868b 361 SUPERFAMILY SSF56112 22 356 3.94E-62 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 SUPERFAMILY SSF52540 7 219 2.14E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 SUPERFAMILY SSF50465 315 416 1.41E-32 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 SUPERFAMILY SSF50447 226 312 3.33E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Gene3D G3DSA:3.40.50.300 425 619 3.4E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Gene3D G3DSA:3.40.50.300 6 218 2.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Pfam PF00009 Elongation factor Tu GTP binding domain 10 196 2.8E-36 T 06-07-2017 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 67 82 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 12 416 2.7E-168 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Gene3D G3DSA:2.40.30.10 314 415 4.1E-9 T 06-07-2017 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Pfam PF01583 Adenylylsulphate kinase 447 598 4.7E-66 T 06-07-2017 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 445 617 36.431 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 PRINTS PR00315 GTP-binding elongation factor signature 13 26 7.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 PRINTS PR00315 GTP-binding elongation factor signature 147 156 7.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 PRINTS PR00315 GTP-binding elongation factor signature 74 82 7.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 PRINTS PR00315 GTP-binding elongation factor signature 94 104 7.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 PRINTS PR00315 GTP-binding elongation factor signature 110 121 7.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 435 611 1.7E-68 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 SUPERFAMILY SSF52540 442 616 2.0E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26670 e9a8ee73d01dea319633ab13c421cb73 621 Gene3D G3DSA:2.40.30.10 227 308 2.7E-11 T 06-07-2017 CAK95_RS20740 c8bf8d6cd4ec62ff290d41ab94959f1a 210 Pfam PF07238 PilZ domain 124 200 5.8E-6 T 06-07-2017 IPR009875 PilZ domain GO:0035438 CAK95_RS20740 c8bf8d6cd4ec62ff290d41ab94959f1a 210 Pfam PF07238 PilZ domain 21 75 5.5E-7 T 06-07-2017 IPR009875 PilZ domain GO:0035438 CAK95_RS20740 c8bf8d6cd4ec62ff290d41ab94959f1a 210 SUPERFAMILY SSF141371 122 202 1.71E-7 T 06-07-2017 CAK95_RS20740 c8bf8d6cd4ec62ff290d41ab94959f1a 210 SUPERFAMILY SSF141371 19 89 1.86E-8 T 06-07-2017 CAK95_RS01070 f46ffdcda13e035164f7b21b9fb13f75 327 PIRSF PIRSF017082 4 323 4.2E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01070 f46ffdcda13e035164f7b21b9fb13f75 327 SUPERFAMILY SSF53850 107 288 1.52E-12 T 06-07-2017 CAK95_RS01070 f46ffdcda13e035164f7b21b9fb13f75 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 318 1.7E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 Gene3D G3DSA:1.10.1040.10 171 266 7.9E-15 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 SUPERFAMILY SSF51735 5 155 4.9E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 Gene3D G3DSA:3.40.50.720 5 151 1.0E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 Pfam PF09130 Domain of unknown function (DUF1932) 190 258 4.9E-22 T 06-07-2017 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 SUPERFAMILY SSF48179 163 269 1.33E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS10395 0ead1beb3eb168e9094743b0309168d2 309 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 141 6.8E-12 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 Gene3D G3DSA:3.40.50.10300 185 402 7.3E-86 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 372 4.5E-69 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 Pfam PF02441 Flavoprotein 4 132 1.4E-31 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 395 8.6E-123 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 SUPERFAMILY SSF102645 186 401 7.46E-75 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 Gene3D G3DSA:3.40.50.1950 3 184 3.1E-60 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS11045 1e0ac736b30e61c2c68a93204b33cd67 405 SUPERFAMILY SSF52507 2 179 6.02E-56 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 Pfam PF00281 Ribosomal protein L5 32 88 3.2E-25 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 Gene3D G3DSA:3.30.1440.10 10 186 1.8E-71 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 ProSitePatterns PS00358 Ribosomal protein L5 signature. 65 81 - T 06-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 SUPERFAMILY SSF55282 11 186 3.06E-72 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 9 187 41.336 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 PIRSF PIRSF002161 5 187 1.5E-61 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21325 c0307fc9bfbab665df161e1f05d586b3 187 Pfam PF00673 ribosomal L5P family C-terminus 93 185 2.2E-39 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 SUPERFAMILY SSF51905 263 376 5.39E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 SUPERFAMILY SSF51905 6 177 5.39E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 343 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 6.9E-40 T 06-07-2017 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 Gene3D G3DSA:3.50.50.60 5 182 5.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 Gene3D G3DSA:3.50.50.60 264 349 5.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11360 63d422037f069ad5baf78f8caa78ee5b 555 Pfam PF01494 FAD binding domain 6 340 2.0E-70 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS28445 f6904d585f9a0ffd574df0ad6822dfc5 102 PIRSF PIRSF028744 1 102 8.3E-38 T 06-07-2017 IPR014056 Addiction module killer protein, predicted CAK95_RS28445 f6904d585f9a0ffd574df0ad6822dfc5 102 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 8 98 4.8E-37 T 06-07-2017 IPR014056 Addiction module killer protein, predicted CAK95_RS19000 c7e1c469615dd284cfc928d2607b3f6a 123 SUPERFAMILY SSF48371 5 122 6.62E-38 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK95_RS19000 c7e1c469615dd284cfc928d2607b3f6a 123 Gene3D G3DSA:1.25.40.70 10 118 5.4E-42 T 06-07-2017 IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain CAK95_RS19000 c7e1c469615dd284cfc928d2607b3f6a 123 Pfam PF09450 Domain of unknown function (DUF2019) 12 116 6.8E-41 T 06-07-2017 IPR018568 Domain of unknown function DUF2019 CAK95_RS15725 a7f002e23deb5250c548d396d9cf1059 233 Pfam PF02586 SOS response associated peptidase (SRAP) 1 209 2.5E-65 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS15725 a7f002e23deb5250c548d396d9cf1059 233 SUPERFAMILY SSF143081 2 219 5.49E-79 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS15725 a7f002e23deb5250c548d396d9cf1059 233 Gene3D G3DSA:3.90.1680.10 1 219 4.9E-73 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 PIRSF PIRSF002181 1 153 3.4E-53 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 142 3.3E-58 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 Gene3D G3DSA:3.90.1180.10 3 142 4.1E-61 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 142 28.147 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 SUPERFAMILY SSF52161 1 140 1.44E-56 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22655 1cb011fa3ee42fded32b5da4934972b1 153 Pfam PF00572 Ribosomal protein L13 14 139 3.7E-53 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK95_RS20500 d6f20938a21d488902c0e329d48df491 154 Pfam PF06186 Protein of unknown function (DUF992) 16 154 1.4E-50 T 06-07-2017 IPR009333 Protein of unknown function DUF992 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 229 533 2.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 SMART SM00100 12 130 8.5E-8 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 333 341 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 507 525 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 371 395 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 278 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 425 441 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 230 252 4.7E-34 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Pfam PF00027 Cyclic nucleotide-binding domain 32 115 7.0E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Gene3D G3DSA:2.60.120.10 13 130 2.2E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 SUPERFAMILY SSF51905 218 544 1.11E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Gene3D G3DSA:3.50.50.60 348 469 3.3E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Gene3D G3DSA:3.50.50.60 227 347 4.2E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 Gene3D G3DSA:3.50.50.60 470 546 4.2E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 SUPERFAMILY SSF51206 13 138 3.01E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 250 4.2E-24 T 06-07-2017 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 519 4.2E-24 T 06-07-2017 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 350 4.2E-24 T 06-07-2017 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 461 477 4.2E-24 T 06-07-2017 CAK95_RS16255 4eed9d8fe39a334b0eea8c888e55b85c 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 375 393 4.2E-24 T 06-07-2017 CAK95_RS26880 519ccafe6f85c12ef34b5eb661ee5b2b 217 Gene3D G3DSA:3.40.50.300 1 211 1.2E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26880 519ccafe6f85c12ef34b5eb661ee5b2b 217 SMART SM00382 30 206 7.6E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS26880 519ccafe6f85c12ef34b5eb661ee5b2b 217 SUPERFAMILY SSF52540 2 212 3.11E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26880 519ccafe6f85c12ef34b5eb661ee5b2b 217 Pfam PF00005 ABC transporter 21 150 2.2E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS23300 af9a6c227ddfff7482facf8d31ba6ce4 265 SMART SM00849 37 238 6.0E-5 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23300 af9a6c227ddfff7482facf8d31ba6ce4 265 Pfam PF12706 Beta-lactamase superfamily domain 53 235 1.7E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23300 af9a6c227ddfff7482facf8d31ba6ce4 265 SUPERFAMILY SSF56281 6 264 1.49E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23300 af9a6c227ddfff7482facf8d31ba6ce4 265 Gene3D G3DSA:3.60.15.10 4 265 2.0E-69 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS08340 151f85df577a04874395e40ac7a940b8 276 SUPERFAMILY SSF161098 77 258 1.19E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08340 151f85df577a04874395e40ac7a940b8 276 Gene3D G3DSA:1.10.3720.10 77 265 8.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08340 151f85df577a04874395e40ac7a940b8 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 259 4.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 SUPERFAMILY SSF46689 5 86 1.54E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 Gene3D G3DSA:1.10.10.60 4 68 1.4E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 Gene3D G3DSA:1.10.357.10 77 193 1.3E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 171 1.3E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 2.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS28215 f3152575371b23fbe67373715e4fe1a5 198 SUPERFAMILY SSF48498 82 194 6.68E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 SUPERFAMILY SSF46785 17 103 7.55E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 Gene3D G3DSA:1.10.10.10 9 104 8.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 Pfam PF01022 Bacterial regulatory protein, arsR family 28 74 1.6E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS24810 414143ea346abc5de20ee8ddf5717e8a 106 SMART SM00418 21 100 1.9E-27 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS01705 7b7f3491b47c744c1f93ba7f224aa84b 301 PIRSF PIRSF000401 19 301 2.3E-51 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CAK95_RS01705 7b7f3491b47c744c1f93ba7f224aa84b 301 Gene3D G3DSA:3.40.50.150 121 294 1.3E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01705 7b7f3491b47c744c1f93ba7f224aa84b 301 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 50 299 2.0E-55 T 06-07-2017 CAK95_RS01705 7b7f3491b47c744c1f93ba7f224aa84b 301 SUPERFAMILY SSF53335 58 298 9.49E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS28290 072905daa13d20da6ba1945fab3bedc4 288 SUPERFAMILY SSF52096 32 287 8.87E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS28290 072905daa13d20da6ba1945fab3bedc4 288 Pfam PF00378 Enoyl-CoA hydratase/isomerase 39 287 2.8E-29 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS28290 072905daa13d20da6ba1945fab3bedc4 288 Gene3D G3DSA:3.90.226.10 29 282 1.7E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07305 8ad1cd5a7ac3fe00aa6ce161513c11d2 242 SUPERFAMILY SSF117396 3 241 7.98E-80 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS07305 8ad1cd5a7ac3fe00aa6ce161513c11d2 242 Gene3D G3DSA:3.20.20.410 2 241 4.6E-82 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS07305 8ad1cd5a7ac3fe00aa6ce161513c11d2 242 Pfam PF01904 Protein of unknown function DUF72 21 238 7.2E-65 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 SUPERFAMILY SSF56801 2 500 9.16E-132 T 06-07-2017 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Pfam PF00501 AMP-binding enzyme 9 408 6.1E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Gene3D G3DSA:3.30.300.30 405 499 5.3E-28 T 06-07-2017 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Gene3D G3DSA:3.40.50.980 160 311 1.7E-31 T 06-07-2017 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Gene3D G3DSA:3.40.50.980 3 159 4.3E-37 T 06-07-2017 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 488 6.1E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 Gene3D G3DSA:2.30.38.10 329 402 4.4E-22 T 06-07-2017 CAK95_RS11540 654f60a38b8486c7dad6ec12cc40f52b 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 Gene3D G3DSA:2.30.40.10 6 70 8.5E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 Gene3D G3DSA:3.20.20.140 71 407 1.7E-96 T 06-07-2017 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 SUPERFAMILY SSF51556 57 368 2.31E-92 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 Pfam PF01979 Amidohydrolase family 54 421 1.7E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 SUPERFAMILY SSF51338 367 431 4.66E-33 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 SUPERFAMILY SSF51338 5 56 4.66E-33 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS15705 3fc3989610040d9eea0716974b1973ae 444 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 22 424 7.0E-97 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK95_RS28705 c4caac023056975007e7d8631d2de5b8 259 SMART SM00382 30 233 1.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28705 c4caac023056975007e7d8631d2de5b8 259 Gene3D G3DSA:3.40.50.300 5 255 2.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28705 c4caac023056975007e7d8631d2de5b8 259 SUPERFAMILY SSF52540 5 255 4.5E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28705 c4caac023056975007e7d8631d2de5b8 259 Pfam PF00005 ABC transporter 21 184 4.0E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.0E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 SUPERFAMILY SSF51735 6 254 6.48E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 8.0E-58 T 06-07-2017 CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 2.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 2.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12975 d18d18b727c208a6446b0ec61d1f9ac5 257 Gene3D G3DSA:3.40.50.720 7 254 1.7E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 Pfam PF00005 ABC transporter 17 162 2.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 SUPERFAMILY SSF52540 2 231 2.28E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 PIRSF PIRSF039137 1 234 1.8E-101 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 SMART SM00382 26 219 1.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00375 c0e54aaa27d63cbe355af0288bedb3a0 234 Gene3D G3DSA:3.40.50.300 2 228 2.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 Gene3D G3DSA:3.40.50.720 214 349 1.1E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 SUPERFAMILY SSF51735 178 375 1.17E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 Pfam PF00107 Zinc-binding dehydrogenase 216 365 3.5E-40 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 SUPERFAMILY SSF50129 32 210 3.14E-32 T 06-07-2017 IPR011032 GroES-like CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 59 170 1.7E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 24 411 2.7E-184 T 06-07-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 Gene3D G3DSA:3.90.180.10 33 213 1.9E-33 T 06-07-2017 IPR011032 GroES-like CAK95_RS11905 a4e7f04765d8ca5c8e7e369cb9a115a4 422 SMART SM00829 44 401 8.1E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS24625 8bbfe28eec21ded32537d09c04dd3a1e 370 SUPERFAMILY SSF56349 62 349 1.71E-39 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS24625 8bbfe28eec21ded32537d09c04dd3a1e 370 Gene3D G3DSA:1.10.443.10 175 348 2.4E-35 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS24625 8bbfe28eec21ded32537d09c04dd3a1e 370 Pfam PF00589 Phage integrase family 188 344 1.2E-27 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS16780 f09b62220e05539318f59a2923d4ed60 198 SUPERFAMILY SSF46689 7 69 6.31E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16780 f09b62220e05539318f59a2923d4ed60 198 Gene3D G3DSA:1.10.357.10 76 188 8.3E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS16780 f09b62220e05539318f59a2923d4ed60 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16780 f09b62220e05539318f59a2923d4ed60 198 Gene3D G3DSA:1.10.10.60 10 62 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16780 f09b62220e05539318f59a2923d4ed60 198 SUPERFAMILY SSF48498 81 188 4.14E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 75 386 4.7E-91 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 Gene3D G3DSA:2.30.330.10 310 389 3.1E-10 T 06-07-2017 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 317 387 2.1E-18 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 Pfam PF02154 Flagellar motor switch protein FliM 104 294 6.1E-64 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 SUPERFAMILY SSF103039 110 295 3.4E-10 T 06-07-2017 IPR028976 CheC-like domain CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 PRINTS PR00955 Flagellar motor switch protein FliM signature 178 197 2.9E-23 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 PRINTS PR00955 Flagellar motor switch protein FliM signature 277 295 2.9E-23 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 PRINTS PR00955 Flagellar motor switch protein FliM signature 153 169 2.9E-23 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 PRINTS PR00955 Flagellar motor switch protein FliM signature 74 87 2.9E-23 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAK95_RS18220 098748add849bfd0486212c5fa59e1e2 410 SUPERFAMILY SSF101801 313 390 1.83E-13 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 SUPERFAMILY SSF51338 377 447 1.76E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 SUPERFAMILY SSF51338 7 55 1.76E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 Gene3D G3DSA:2.30.40.10 9 67 5.3E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 SUPERFAMILY SSF51556 56 377 1.44E-74 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 Pfam PF01979 Amidohydrolase family 52 431 3.3E-16 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS01190 05244921b816dde5d42c7ae79479ae2b 455 Gene3D G3DSA:3.20.20.140 68 390 1.8E-79 T 06-07-2017 CAK95_RS14615 c819eae136d34782529d6a87c82cf29a 385 SMART SM00244 73 255 3.8E-23 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS14615 c819eae136d34782529d6a87c82cf29a 385 SUPERFAMILY SSF117892 138 258 2.09E-18 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS14615 c819eae136d34782529d6a87c82cf29a 385 Pfam PF12221 Bacterial membrane protein N terminal 1 52 6.5E-10 T 06-07-2017 IPR020980 Menbrane protein HflK, N-terminal CAK95_RS14615 c819eae136d34782529d6a87c82cf29a 385 TIGRFAM TIGR01933 hflK: HflK protein 75 346 6.3E-82 T 06-07-2017 IPR010201 HflK GO:0016021 CAK95_RS14615 c819eae136d34782529d6a87c82cf29a 385 Pfam PF01145 SPFH domain / Band 7 family 77 271 5.1E-26 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS12095 2ca10cc254bf0771e37d9d95ab438425 131 Gene3D G3DSA:3.30.1330.40 4 130 1.3E-29 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS12095 2ca10cc254bf0771e37d9d95ab438425 131 SUPERFAMILY SSF55298 3 129 1.34E-27 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS12095 2ca10cc254bf0771e37d9d95ab438425 131 Pfam PF01042 Endoribonuclease L-PSP 13 129 1.2E-18 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS03830 ddedc58630bb7a3327304ec58f1ff6b6 343 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 1 342 1.0E-128 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAK95_RS03830 ddedc58630bb7a3327304ec58f1ff6b6 343 Pfam PF13816 Haem-containing dehydratase 44 339 1.6E-86 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAK95_RS08065 0e0201b3ab270571fdc62b5cd8802edd 203 Hamap MF_00528 Septum formation protein Maf [maf]. 9 202 24.51 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS08065 0e0201b3ab270571fdc62b5cd8802edd 203 SUPERFAMILY SSF52972 9 195 3.6E-45 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS08065 0e0201b3ab270571fdc62b5cd8802edd 203 PIRSF PIRSF006305 1 200 7.5E-40 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS08065 0e0201b3ab270571fdc62b5cd8802edd 203 Gene3D G3DSA:3.90.950.10 9 194 1.2E-43 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS08065 0e0201b3ab270571fdc62b5cd8802edd 203 Pfam PF02545 Maf-like protein 10 194 7.2E-36 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Gene3D G3DSA:2.60.260.20 256 335 2.0E-25 T 06-07-2017 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Gene3D G3DSA:2.10.230.10 141 209 4.4E-23 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Pfam PF01556 DnaJ C terminal domain 121 334 3.8E-42 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 370 40.239 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 06-07-2017 IPR018253 DnaJ domain, conserved site CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SMART SM00271 4 62 9.4E-29 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Gene3D G3DSA:1.10.287.110 1 102 6.9E-32 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Gene3D G3DSA:2.60.260.20 111 140 3.3E-23 T 06-07-2017 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Gene3D G3DSA:2.60.260.20 210 251 3.3E-23 T 06-07-2017 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SUPERFAMILY SSF49493 213 266 1.7E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SUPERFAMILY SSF49493 114 152 1.7E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 PRINTS PR00625 DnaJ domain signature 25 40 8.5E-26 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 PRINTS PR00625 DnaJ domain signature 42 62 8.5E-26 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 PRINTS PR00625 DnaJ domain signature 62 81 8.5E-26 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 PRINTS PR00625 DnaJ domain signature 7 25 8.5E-26 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 350 2.4E-130 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Pfam PF00226 DnaJ domain 6 67 1.3E-24 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SUPERFAMILY SSF46565 1 103 6.41E-32 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SUPERFAMILY SSF49493 259 345 8.76E-25 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 Pfam PF00684 DnaJ central domain 147 207 4.2E-13 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK95_RS08920 b83d7d4111dcd8cd20ab49d0fead1eac 379 SUPERFAMILY SSF57938 134 210 2.75E-21 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK95_RS11665 6de2b7a4a385be3b1afb3c48cf696a1a 233 Gene3D G3DSA:3.40.50.300 1 227 8.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11665 6de2b7a4a385be3b1afb3c48cf696a1a 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS11665 6de2b7a4a385be3b1afb3c48cf696a1a 233 SMART SM00382 26 210 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11665 6de2b7a4a385be3b1afb3c48cf696a1a 233 Pfam PF00005 ABC transporter 19 161 4.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11665 6de2b7a4a385be3b1afb3c48cf696a1a 233 SUPERFAMILY SSF52540 2 226 2.66E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23630 7fe4c894566237ac51ab03a96fd98c54 97 Pfam PF03937 Flavinator of succinate dehydrogenase 15 86 2.3E-24 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAK95_RS23630 7fe4c894566237ac51ab03a96fd98c54 97 SUPERFAMILY SSF109910 10 88 4.71E-26 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAK95_RS23630 7fe4c894566237ac51ab03a96fd98c54 97 Gene3D G3DSA:1.10.150.250 10 93 7.7E-28 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAK95_RS22820 be867b71f045f67fe7fafb9b62db4679 424 Pfam PF01734 Patatin-like phospholipase 114 292 5.1E-14 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS22820 be867b71f045f67fe7fafb9b62db4679 424 Gene3D G3DSA:3.40.1090.10 115 293 1.0E-11 T 06-07-2017 CAK95_RS22820 be867b71f045f67fe7fafb9b62db4679 424 SUPERFAMILY SSF52151 114 333 2.46E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS13735 eab38bbaf028b4634015833d35996024 214 Pfam PF13578 Methyltransferase domain 53 173 2.9E-22 T 06-07-2017 CAK95_RS13735 eab38bbaf028b4634015833d35996024 214 Gene3D G3DSA:3.40.50.150 47 201 4.9E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13735 eab38bbaf028b4634015833d35996024 214 SUPERFAMILY SSF53335 18 176 5.01E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS07920 e4192dce6db323cd6e038db817c187da 277 SUPERFAMILY SSF52540 15 257 4.6E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07920 e4192dce6db323cd6e038db817c187da 277 Pfam PF00005 ABC transporter 36 181 5.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS07920 e4192dce6db323cd6e038db817c187da 277 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS07920 e4192dce6db323cd6e038db817c187da 277 Gene3D G3DSA:3.40.50.300 12 236 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07920 e4192dce6db323cd6e038db817c187da 277 SMART SM00382 43 233 1.8E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 SMART SM00862 37 110 8.1E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 Gene3D G3DSA:1.10.10.10 16 111 2.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 SUPERFAMILY SSF46894 18 111 1.3E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 SUPERFAMILY SSF48452 299 498 4.17E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 Gene3D G3DSA:3.40.50.10070 135 238 3.8E-4 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 Gene3D G3DSA:1.25.40.10 298 499 8.9E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18055 642270fde82f71116c44bacffddd8d5e 530 Pfam PF00486 Transcriptional regulatory protein, C terminal 37 110 3.2E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS00905 03785dc20c2e4eba0ea8265358ba47ce 237 SUPERFAMILY SSF52540 6 226 1.41E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00905 03785dc20c2e4eba0ea8265358ba47ce 237 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00905 03785dc20c2e4eba0ea8265358ba47ce 237 Gene3D G3DSA:3.40.50.300 6 225 5.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00905 03785dc20c2e4eba0ea8265358ba47ce 237 SMART SM00382 30 211 5.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00905 03785dc20c2e4eba0ea8265358ba47ce 237 Pfam PF00005 ABC transporter 22 161 2.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10375 af1de1d859de39f05121be358719d66f 261 Pfam PF13763 Domain of unknown function (DUF4167) 11 88 1.1E-31 T 06-07-2017 IPR025430 Domain of unknown function DUF4167 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.521 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.9E-25 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 Pfam PF00831 Ribosomal L29 protein 5 60 9.1E-26 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 SUPERFAMILY SSF46561 1 62 1.57E-22 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 Gene3D G3DSA:1.10.287.310 1 61 5.2E-29 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21305 091b80025af2e263eb083349d0ef1307 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS15230 e8a2aed0c4a32af826aac645d06ad3c6 139 Pfam PF02050 Flagellar FliJ protein 17 132 2.2E-10 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CAK95_RS15230 e8a2aed0c4a32af826aac645d06ad3c6 139 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 134 2.1E-21 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CAK95_RS22215 da70c54aee723a3e47da30f16f431342 247 Gene3D G3DSA:2.40.160.20 14 242 2.6E-31 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS22215 da70c54aee723a3e47da30f16f431342 247 Pfam PF13505 Outer membrane protein beta-barrel domain 22 233 9.0E-16 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS22215 da70c54aee723a3e47da30f16f431342 247 SUPERFAMILY SSF56925 22 236 5.23E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 SUPERFAMILY SSF52821 7 157 1.7E-45 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 Pfam PF00581 Rhodanese-like domain 14 133 6.5E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 Pfam PF00581 Rhodanese-like domain 164 275 8.7E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 Gene3D G3DSA:3.40.250.10 2 156 2.4E-47 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 SUPERFAMILY SSF52821 171 284 1.31E-33 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 Gene3D G3DSA:3.40.250.10 159 284 1.5E-40 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 SMART SM00450 160 279 1.7E-18 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24190 09d0280450aadc4bfa73439c132704ca 285 SMART SM00450 13 137 1.2E-24 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 Gene3D G3DSA:1.10.10.10 40 113 1.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 SMART SM00346 42 132 6.2E-24 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 Pfam PF09339 IclR helix-turn-helix domain 44 94 2.8E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 Gene3D G3DSA:3.30.450.40 114 289 6.9E-53 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 SUPERFAMILY SSF55781 108 288 2.62E-47 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 SUPERFAMILY SSF46785 42 116 2.02E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10060 1fa70871f3da1dcc0438a56e5f1ebb68 301 Pfam PF01614 Bacterial transcriptional regulator 166 285 4.1E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS14600 2352f15a006ac8bfd8e21bf5601f1826 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 330 3.2E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14600 2352f15a006ac8bfd8e21bf5601f1826 333 SUPERFAMILY SSF53850 123 290 1.41E-10 T 06-07-2017 CAK95_RS14600 2352f15a006ac8bfd8e21bf5601f1826 333 PIRSF PIRSF017082 1 333 1.8E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10295 c1ebb5094998108591238df56fdfd0e8 251 SMART SM00382 33 220 1.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10295 c1ebb5094998108591238df56fdfd0e8 251 Pfam PF00005 ABC transporter 26 172 2.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10295 c1ebb5094998108591238df56fdfd0e8 251 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS10295 c1ebb5094998108591238df56fdfd0e8 251 SUPERFAMILY SSF52540 4 226 1.56E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10295 c1ebb5094998108591238df56fdfd0e8 251 Gene3D G3DSA:3.40.50.300 2 231 3.3E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28585 83b23767df09620e8d80169d33b5a653 291 Gene3D G3DSA:3.40.50.1820 42 281 5.2E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28585 83b23767df09620e8d80169d33b5a653 291 SUPERFAMILY SSF53474 37 278 1.43E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28585 83b23767df09620e8d80169d33b5a653 291 Pfam PF12697 Alpha/beta hydrolase family 44 275 2.9E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27415 bf2df4cadea1e967df9ded77c97ea129 513 Gene3D G3DSA:3.10.105.10 288 483 1.8E-33 T 06-07-2017 CAK95_RS27415 bf2df4cadea1e967df9ded77c97ea129 513 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 431 7.5E-67 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS27415 bf2df4cadea1e967df9ded77c97ea129 513 SUPERFAMILY SSF53850 30 506 3.08E-96 T 06-07-2017 CAK95_RS27415 bf2df4cadea1e967df9ded77c97ea129 513 Gene3D G3DSA:3.40.190.10 139 287 4.8E-35 T 06-07-2017 CAK95_RS27415 bf2df4cadea1e967df9ded77c97ea129 513 PIRSF PIRSF002741 13 504 1.6E-66 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS13435 7eb66e7687bcc84a51f34c865e4fae21 311 Pfam PF01040 UbiA prenyltransferase family 46 287 4.3E-59 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK95_RS13435 7eb66e7687bcc84a51f34c865e4fae21 311 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 85 107 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site CAK95_RS13435 7eb66e7687bcc84a51f34c865e4fae21 311 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 24 305 6.0E-112 T 06-07-2017 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CAK95_RS13435 7eb66e7687bcc84a51f34c865e4fae21 311 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 19 306 28.306 T 06-07-2017 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 Gene3D G3DSA:2.40.128.10 133 224 2.9E-8 T 06-07-2017 IPR003086 Metalloprotease inhibitor I38 GO:0004866|GO:0030288 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 Gene3D G3DSA:2.40.128.10 25 121 9.9E-11 T 06-07-2017 IPR003086 Metalloprotease inhibitor I38 GO:0004866|GO:0030288 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 Pfam PF02974 Protease inhibitor Inh 25 114 2.9E-15 T 06-07-2017 IPR021140 Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 Pfam PF02974 Protease inhibitor Inh 133 222 2.2E-12 T 06-07-2017 IPR021140 Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 SUPERFAMILY SSF50882 25 120 2.88E-17 T 06-07-2017 IPR016085 Protease inhibitor, beta-barrel domain GO:0004866 CAK95_RS08270 330d8a2af9f9971c4ea5f826f3115890 227 SUPERFAMILY SSF50882 132 225 1.41E-17 T 06-07-2017 IPR016085 Protease inhibitor, beta-barrel domain GO:0004866 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 Pfam PF03734 L,D-transpeptidase catalytic domain 416 556 1.6E-26 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 Gene3D G3DSA:2.40.440.10 508 556 2.1E-9 T 06-07-2017 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 Gene3D G3DSA:2.40.440.10 412 460 2.1E-9 T 06-07-2017 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 Gene3D G3DSA:1.10.101.10 324 389 9.7E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 Pfam PF01471 Putative peptidoglycan binding domain 343 386 3.2E-9 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 SUPERFAMILY SSF141523 413 469 6.41E-19 T 06-07-2017 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 SUPERFAMILY SSF141523 506 557 6.41E-19 T 06-07-2017 CAK95_RS28460 38ce2e6418a80f42fe6f39a900e194fe 703 SUPERFAMILY SSF47090 323 387 7.14E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 Pfam PF01668 SmpB protein 11 74 1.6E-28 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 136 8.0E-53 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 153 5.5E-57 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 SUPERFAMILY SSF74982 6 136 3.14E-50 T 06-07-2017 IPR023620 Small protein B CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 Hamap MF_00023 SsrA-binding protein [smpB]. 1 157 71.93 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK95_RS23750 7069e12d5817d9632329ead4e58b3056 157 Gene3D G3DSA:2.40.280.10 10 131 9.1E-51 T 06-07-2017 IPR023620 Small protein B CAK95_RS20795 d3555f91c9617ee886da2e942faa1165 115 SMART SM01234 19 86 3.4E-33 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK95_RS20795 d3555f91c9617ee886da2e942faa1165 115 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 34 86 2.0E-19 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK95_RS20795 d3555f91c9617ee886da2e942faa1165 115 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 19 87 20.814 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK95_RS20795 d3555f91c9617ee886da2e942faa1165 115 Pfam PF01809 Haemolytic domain 23 86 5.0E-24 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK95_RS20795 d3555f91c9617ee886da2e942faa1165 115 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 25 92 4.1E-23 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK95_RS25565 fadc189535aa159e84ffcb21f0e228c6 101 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 1 95 23.529 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CAK95_RS25565 fadc189535aa159e84ffcb21f0e228c6 101 Gene3D G3DSA:3.30.1390.10 6 100 5.4E-35 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS25565 fadc189535aa159e84ffcb21f0e228c6 101 SUPERFAMILY SSF54736 15 99 1.57E-26 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS25565 fadc189535aa159e84ffcb21f0e228c6 101 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 18 95 2.6E-27 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CAK95_RS22130 db5e786be54d25c3b00dccc5b4b6f803 103 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 26 100 5.7E-24 T 06-07-2017 IPR014543 Uncharacterised conserved protein UCP028291 CAK95_RS05715 c5e1dd3f5733da2158a213d16966bacb 72 SUPERFAMILY SSF82057 5 72 9.61E-25 T 06-07-2017 CAK95_RS05715 c5e1dd3f5733da2158a213d16966bacb 72 Pfam PF03831 PhnA domain 6 72 2.5E-29 T 06-07-2017 IPR013988 PhnA protein, C-terminal CAK95_RS05715 c5e1dd3f5733da2158a213d16966bacb 72 Gene3D G3DSA:2.30.30.40 5 72 8.4E-31 T 06-07-2017 CAK95_RS09800 532147827acd78402ed0d3a80daf9f99 396 SUPERFAMILY SSF51569 64 340 3.91E-11 T 06-07-2017 CAK95_RS09800 532147827acd78402ed0d3a80daf9f99 396 Gene3D G3DSA:3.20.20.70 66 326 7.3E-4 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS09800 532147827acd78402ed0d3a80daf9f99 396 Pfam PF06187 Protein of unknown function (DUF993) 13 394 1.9E-189 T 06-07-2017 IPR009334 Protein of unknown function DUF993 CAK95_RS19515 01173e01e2d65f0ea5d8d74950906010 169 Pfam PF11000 Protein of unknown function (DUF2840) 19 166 3.4E-73 T 06-07-2017 IPR021263 Protein of unknown function DUF2840 CAK95_RS06665 4a5807e7024e51a7997cf841d23273b4 422 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 163 340 1.3E-9 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK95_RS06665 4a5807e7024e51a7997cf841d23273b4 422 Gene3D G3DSA:3.40.50.300 159 398 2.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06665 4a5807e7024e51a7997cf841d23273b4 422 SUPERFAMILY SSF52172 68 151 2.09E-5 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06665 4a5807e7024e51a7997cf841d23273b4 422 SUPERFAMILY SSF52540 160 401 9.81E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17510 321ac28266ced23541362d974f5cc4c9 115 Gene3D G3DSA:2.60.120.10 3 105 4.7E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS17510 321ac28266ced23541362d974f5cc4c9 115 Pfam PF07883 Cupin domain 36 98 1.5E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS17510 321ac28266ced23541362d974f5cc4c9 115 SUPERFAMILY SSF51182 12 106 4.45E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS07500 1afd6d9f3829c7ce99b4ef38f5fba364 391 Pfam PF03969 AFG1-like ATPase 5 371 1.1E-128 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAK95_RS07500 1afd6d9f3829c7ce99b4ef38f5fba364 391 SUPERFAMILY SSF52540 61 203 1.1E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07500 1afd6d9f3829c7ce99b4ef38f5fba364 391 Gene3D G3DSA:3.40.50.300 52 205 3.3E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24775 4f433a53b735036e198dcae459654676 332 SUPERFAMILY SSF56655 12 324 4.58E-103 T 06-07-2017 CAK95_RS24775 4f433a53b735036e198dcae459654676 332 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 14 324 3.3E-99 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK95_RS24775 4f433a53b735036e198dcae459654676 332 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 16 323 7.3E-135 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK95_RS24775 4f433a53b735036e198dcae459654676 332 PIRSF PIRSF004532 13 332 2.0E-138 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK95_RS24775 4f433a53b735036e198dcae459654676 332 Gene3D G3DSA:3.30.540.10 186 325 6.5E-39 T 06-07-2017 CAK95_RS24775 4f433a53b735036e198dcae459654676 332 Gene3D G3DSA:3.30.540.10 13 185 3.3E-60 T 06-07-2017 CAK95_RS15790 7355b210dadc0d84940fb85687cb933d 305 SUPERFAMILY SSF56281 20 288 2.17E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15790 7355b210dadc0d84940fb85687cb933d 305 SMART SM00849 40 216 4.4E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15790 7355b210dadc0d84940fb85687cb933d 305 Gene3D G3DSA:3.60.15.10 18 242 7.1E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15790 7355b210dadc0d84940fb85687cb933d 305 Pfam PF00753 Metallo-beta-lactamase superfamily 40 216 6.4E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS25620 54667838772df50180aa47c1ab9a5371 148 SUPERFAMILY SSF54427 11 128 7.68E-11 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25620 54667838772df50180aa47c1ab9a5371 148 Gene3D G3DSA:3.10.450.50 18 129 1.2E-8 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25620 54667838772df50180aa47c1ab9a5371 148 Pfam PF12680 SnoaL-like domain 26 124 5.7E-9 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS24795 4405265a9c3e66fad01f36147d5fdc44 602 SUPERFAMILY SSF53474 242 528 3.11E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24795 4405265a9c3e66fad01f36147d5fdc44 602 Gene3D G3DSA:3.40.50.1820 214 572 2.4E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24795 4405265a9c3e66fad01f36147d5fdc44 602 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 72 600 2.5E-225 T 06-07-2017 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 CAK95_RS24795 4405265a9c3e66fad01f36147d5fdc44 602 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 113 284 4.5E-73 T 06-07-2017 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 CAK95_RS25010 218f3bb5a720f1b1ad987bbb3eb24659 386 SUPERFAMILY SSF53383 5 373 6.31E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS25010 218f3bb5a720f1b1ad987bbb3eb24659 386 Gene3D G3DSA:3.40.640.10 17 246 9.7E-68 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS25010 218f3bb5a720f1b1ad987bbb3eb24659 386 Gene3D G3DSA:3.90.1150.10 247 372 9.7E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS25010 218f3bb5a720f1b1ad987bbb3eb24659 386 Pfam PF00266 Aminotransferase class-V 6 364 8.8E-59 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS25010 218f3bb5a720f1b1ad987bbb3eb24659 386 PIRSF PIRSF005572 2 379 4.9E-118 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Pfam PF00571 CBS domain 340 384 9.5E-9 T 06-07-2017 IPR000644 CBS domain CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Pfam PF00571 CBS domain 397 448 8.3E-7 T 06-07-2017 IPR000644 CBS domain CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Gene3D G3DSA:3.40.50.1100 2 38 1.2E-64 T 06-07-2017 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Gene3D G3DSA:3.40.50.1100 149 315 1.2E-64 T 06-07-2017 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 SUPERFAMILY SSF53686 3 313 2.23E-94 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 SUPERFAMILY SSF54631 325 448 2.15E-21 T 06-07-2017 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 29 47 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Gene3D G3DSA:3.10.580.10 339 448 1.0E-22 T 06-07-2017 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Gene3D G3DSA:3.40.50.1100 39 143 5.4E-33 T 06-07-2017 CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 SMART SM00116 404 449 4.5 T 06-07-2017 IPR000644 CBS domain CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 SMART SM00116 338 385 7.9E-7 T 06-07-2017 IPR000644 CBS domain CAK95_RS24925 6d1fbd9e03c31d11c892802e95ff3071 453 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 298 1.4E-67 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.90.1170.50 16 118 3.6E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 119 191 1.1E-25 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 297 371 1.1E-25 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 SUPERFAMILY SSF56003 122 760 8.77E-151 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 SMART SM01008 22 130 9.0E-46 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 130 3.1E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 192 294 6.5E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 451 583 3.5E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 SUPERFAMILY SSF54665 15 149 7.46E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 373 450 1.2E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Gene3D G3DSA:3.30.365.10 615 759 1.2E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS04930 83a5e659da86f1467958eccec9a07dc0 772 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 697 1.5E-125 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS23120 72c325e73efba779dc5e13881eb34013 130 PRINTS PR01651 Protein-export SecG membrane protein signature 51 73 6.1E-15 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK95_RS23120 72c325e73efba779dc5e13881eb34013 130 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.1E-15 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK95_RS23120 72c325e73efba779dc5e13881eb34013 130 Pfam PF03840 Preprotein translocase SecG subunit 4 70 4.5E-17 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK95_RS23120 72c325e73efba779dc5e13881eb34013 130 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 70 1.4E-20 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK95_RS03900 91148cfba2ab3adad64e38c9ba9340af 107 SUPERFAMILY SSF54909 3 103 1.79E-25 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS03900 91148cfba2ab3adad64e38c9ba9340af 107 Pfam PF07978 NIPSNAP 5 103 5.4E-27 T 06-07-2017 IPR012577 NIPSNAP CAK95_RS03900 91148cfba2ab3adad64e38c9ba9340af 107 Gene3D G3DSA:3.30.70.900 4 105 1.5E-23 T 06-07-2017 CAK95_RS01890 f2e36dd5ba730794a1af13f48ff296d2 358 PIRSF PIRSF017082 31 357 2.5E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01890 f2e36dd5ba730794a1af13f48ff296d2 358 SUPERFAMILY SSF53850 66 311 4.34E-10 T 06-07-2017 CAK95_RS01890 f2e36dd5ba730794a1af13f48ff296d2 358 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 82 351 5.3E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 Gene3D G3DSA:1.10.10.10 215 271 3.2E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 SUPERFAMILY SSF88946 98 207 5.49E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 Pfam PF08281 Sigma-70, region 4 218 268 6.9E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 SUPERFAMILY SSF88659 217 271 4.86E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 Gene3D G3DSA:1.10.1740.10 100 213 5.8E-19 T 06-07-2017 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 120 270 7.6E-17 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18500 b6e2f55252227ef1bb368f19875e403a 276 Pfam PF04542 Sigma-70 region 2 125 191 2.4E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 29.783 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 SUPERFAMILY SSF46906 68 140 2.35E-24 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 3.4E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.8E-23 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 SUPERFAMILY SSF54747 3 72 2.88E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 Gene3D G3DSA:1.10.10.250 73 141 1.3E-29 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 Gene3D G3DSA:3.30.1550.10 2 72 9.9E-38 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 SMART SM00649 9 141 4.8E-81 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 72 7.0E-12 T 06-07-2017 CAK95_RS21175 50217f0272f874de7fdafc5b05252356 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.2E-65 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS03335 468ed9bbabcdcca05e3c43eee1cd26bd 344 Pfam PF13551 Winged helix-turn helix 13 73 4.3E-13 T 06-07-2017 CAK95_RS03335 468ed9bbabcdcca05e3c43eee1cd26bd 344 Gene3D G3DSA:3.30.420.10 157 318 2.7E-23 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS03335 468ed9bbabcdcca05e3c43eee1cd26bd 344 Pfam PF00665 Integrase core domain 160 282 3.9E-18 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK95_RS03335 468ed9bbabcdcca05e3c43eee1cd26bd 344 SUPERFAMILY SSF53098 159 332 1.14E-30 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS03335 468ed9bbabcdcca05e3c43eee1cd26bd 344 SUPERFAMILY SSF46689 15 113 1.67E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 296 4.0E-33 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 Pfam PF00005 ABC transporter 360 517 5.1E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 SMART SM00382 368 566 1.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 SUPERFAMILY SSF52540 343 587 3.61E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 Gene3D G3DSA:3.40.50.300 341 586 1.5E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02160 916cc2ef40b418e6529d342bcf5c85d8 591 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 567 588 5.6E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 290 367 4.0E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 126 180 4.0E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 SUPERFAMILY SSF56003 129 782 9.81E-168 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 633 781 6.8E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 369 461 6.8E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.90.1170.50 3 125 6.4E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 718 1.2E-146 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 462 619 3.2E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Gene3D G3DSA:3.30.365.10 181 288 1.7E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 137 1.5E-24 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 SMART SM01008 22 137 3.1E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS27520 da14f523319f649d29c80d58eb9da39a 785 SUPERFAMILY SSF54665 5 154 4.71E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS09860 8f1e10a2def83d55ade76d1ae961c522 142 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 77 111 1.3E-14 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS09860 8f1e10a2def83d55ade76d1ae961c522 142 Gene3D G3DSA:2.160.10.10 74 130 3.5E-28 T 06-07-2017 CAK95_RS09860 8f1e10a2def83d55ade76d1ae961c522 142 SUPERFAMILY SSF51161 18 128 2.63E-34 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS09980 d3b0dc4efb3b11de76ce962cf4945ce5 389 SUPERFAMILY SSF53822 24 362 4.19E-82 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS09980 d3b0dc4efb3b11de76ce962cf4945ce5 389 Gene3D G3DSA:3.40.50.2300 148 294 4.2E-25 T 06-07-2017 CAK95_RS09980 d3b0dc4efb3b11de76ce962cf4945ce5 389 Pfam PF13458 Periplasmic binding protein 24 358 5.2E-69 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS09980 d3b0dc4efb3b11de76ce962cf4945ce5 389 Gene3D G3DSA:3.40.50.2300 19 146 3.5E-38 T 06-07-2017 CAK95_RS09980 d3b0dc4efb3b11de76ce962cf4945ce5 389 Gene3D G3DSA:3.40.50.2300 295 348 3.5E-38 T 06-07-2017 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 PRINTS PR00721 Stomatin signature 180 201 3.0E-5 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 PRINTS PR00721 Stomatin signature 78 99 3.0E-5 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 PRINTS PR00721 Stomatin signature 161 179 3.0E-5 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 SUPERFAMILY SSF117892 55 192 4.71E-30 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 PIRSF PIRSF005651 4 291 1.6E-96 T 06-07-2017 IPR010200 HflC GO:0016021|GO:0052547 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 TIGRFAM TIGR01932 hflC: HflC protein 151 284 1.2E-40 T 06-07-2017 IPR010200 HflC GO:0016021|GO:0052547 CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 SMART SM00244 23 185 2.0E-43 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS14620 372e24cf18a9adf328192d142cd13324 309 Pfam PF01145 SPFH domain / Band 7 family 31 200 4.5E-31 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 Gene3D G3DSA:3.30.1120.10 461 526 1.1E-8 T 06-07-2017 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 SUPERFAMILY SSF53649 10 115 3.09E-110 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 SUPERFAMILY SSF53649 164 524 3.09E-110 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 Gene3D G3DSA:3.40.720.10 155 437 1.0E-94 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 Gene3D G3DSA:3.40.720.10 9 117 1.0E-94 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 Pfam PF16347 Domain of unknown function (DUF4976) 428 525 8.6E-11 T 06-07-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 CAK95_RS05305 a28448b61ec6b9dbfabb99b0069643e0 536 Pfam PF00884 Sulfatase 11 420 4.2E-61 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS02860 2c9493d2f68be47544307ec05b3efcb9 120 Pfam PF07784 Protein of unknown function (DUF1622) 24 102 4.0E-25 T 06-07-2017 IPR012427 Protein of unknown function DUF1622 CAK95_RS23795 403f70bc07ad686be0f75f1bf1efd492 138 SUPERFAMILY SSF88723 1 128 1.09E-17 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS23795 403f70bc07ad686be0f75f1bf1efd492 138 Pfam PF01850 PIN domain 6 126 1.9E-11 T 06-07-2017 IPR002716 PIN domain CAK95_RS23795 403f70bc07ad686be0f75f1bf1efd492 138 Gene3D G3DSA:3.40.50.1010 4 121 2.5E-5 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS10675 bc28329051309f56ae05f974e85a84a2 266 SUPERFAMILY SSF52540 6 237 8.78E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10675 bc28329051309f56ae05f974e85a84a2 266 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS10675 bc28329051309f56ae05f974e85a84a2 266 Gene3D G3DSA:3.40.50.300 6 215 7.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10675 bc28329051309f56ae05f974e85a84a2 266 Pfam PF00005 ABC transporter 29 168 3.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10675 bc28329051309f56ae05f974e85a84a2 266 SMART SM00382 38 219 3.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04750 d7f8e907aa6bd51c200ae40f65323372 181 SUPERFAMILY SSF55797 52 164 4.71E-16 T 06-07-2017 IPR014044 CAP domain CAK95_RS04750 d7f8e907aa6bd51c200ae40f65323372 181 Pfam PF00188 Cysteine-rich secretory protein family 55 166 1.6E-14 T 06-07-2017 IPR014044 CAP domain CAK95_RS04750 d7f8e907aa6bd51c200ae40f65323372 181 Gene3D G3DSA:3.40.33.10 54 161 1.1E-7 T 06-07-2017 IPR014044 CAP domain CAK95_RS16205 867d2be10b6bc5ba5f7dbb13e4b0df03 208 Pfam PF00857 Isochorismatase family 53 191 7.5E-22 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS16205 867d2be10b6bc5ba5f7dbb13e4b0df03 208 SUPERFAMILY SSF52499 39 194 7.2E-28 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS16205 867d2be10b6bc5ba5f7dbb13e4b0df03 208 Gene3D G3DSA:3.40.50.850 37 193 2.3E-24 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS07325 aac47aae834256c301750520ccffd6f1 219 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 29 212 19.571 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAK95_RS07325 aac47aae834256c301750520ccffd6f1 219 Pfam PF01467 Cytidylyltransferase-like 33 212 5.7E-21 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS07325 aac47aae834256c301750520ccffd6f1 219 SUPERFAMILY SSF52374 28 212 1.09E-38 T 06-07-2017 CAK95_RS07325 aac47aae834256c301750520ccffd6f1 219 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 33 213 3.2E-36 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAK95_RS07325 aac47aae834256c301750520ccffd6f1 219 Gene3D G3DSA:3.40.50.620 30 213 4.4E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS22310 f52f669758d13f13f7720318a17463bc 104 Pfam PF13560 Helix-turn-helix domain 25 77 6.1E-9 T 06-07-2017 CAK95_RS22310 f52f669758d13f13f7720318a17463bc 104 Gene3D G3DSA:1.10.260.40 19 78 4.0E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS22310 f52f669758d13f13f7720318a17463bc 104 SMART SM00530 29 87 4.8E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS22310 f52f669758d13f13f7720318a17463bc 104 SUPERFAMILY SSF47413 22 78 2.28E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS05605 634183b8e9912402070ce1b549cfb4a0 255 SMART SM00267 82 246 4.1E-50 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS05605 634183b8e9912402070ce1b549cfb4a0 255 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 90 245 7.6E-38 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS05605 634183b8e9912402070ce1b549cfb4a0 255 Pfam PF00990 Diguanylate cyclase, GGDEF domain 94 242 5.7E-35 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS05605 634183b8e9912402070ce1b549cfb4a0 255 SUPERFAMILY SSF55073 98 245 2.12E-39 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS05605 634183b8e9912402070ce1b549cfb4a0 255 Gene3D G3DSA:3.30.70.270 95 245 1.8E-43 T 06-07-2017 CAK95_RS12375 925f70f6733bfb84c5c784c42ff9feff 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12375 925f70f6733bfb84c5c784c42ff9feff 236 Gene3D G3DSA:3.40.50.300 2 229 2.7E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12375 925f70f6733bfb84c5c784c42ff9feff 236 SMART SM00382 28 229 7.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12375 925f70f6733bfb84c5c784c42ff9feff 236 SUPERFAMILY SSF52540 3 234 5.55E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12375 925f70f6733bfb84c5c784c42ff9feff 236 Pfam PF00005 ABC transporter 19 164 3.9E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 Gene3D G3DSA:3.10.20.30 16 88 7.6E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 Pfam PF01799 [2Fe-2S] binding domain 87 162 8.3E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 SUPERFAMILY SSF54292 15 92 9.97E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 21 73 7.5E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 Gene3D G3DSA:1.10.150.120 89 167 2.5E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS28595 0ef2dd0010e2a010b734d167517a7300 172 SUPERFAMILY SSF47741 99 170 1.01E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS09205 bde941f3dc9871d75bcc129bb99e4d70 532 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 74 479 2.8E-94 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAK95_RS09205 bde941f3dc9871d75bcc129bb99e4d70 532 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 15 516 21.614 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAK95_RS09205 bde941f3dc9871d75bcc129bb99e4d70 532 Gene3D G3DSA:3.60.110.10 234 491 4.1E-27 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS09205 bde941f3dc9871d75bcc129bb99e4d70 532 SUPERFAMILY SSF56317 236 508 2.62E-42 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS09205 bde941f3dc9871d75bcc129bb99e4d70 532 Pfam PF00795 Carbon-nitrogen hydrolase 289 493 2.9E-27 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 SMART SM00563 454 564 2.7E-20 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:1.20.1250.20 221 423 1.4E-6 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:1.20.1250.20 9 194 1.8E-6 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Pfam PF07690 Major Facilitator Superfamily 9 309 8.8E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 SUPERFAMILY SSF103473 8 419 1.57E-22 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Pfam PF01553 Acyltransferase 438 561 5.7E-15 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:3.40.50.980 801 950 2.9E-35 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 ProSitePatterns PS00455 Putative AMP-binding domain signature. 794 805 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 SUPERFAMILY SSF56801 621 1134 2.22E-98 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:3.40.50.980 628 800 2.8E-19 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 SUPERFAMILY SSF69593 429 622 1.44E-20 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:3.30.300.30 1032 1130 8.2E-11 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:3.40.1130.10 435 595 1.5E-6 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Gene3D G3DSA:2.30.38.10 957 1028 9.4E-13 T 06-07-2017 CAK95_RS08650 c546727f4cd308dc0d041c314bb6dd2b 1142 Pfam PF00501 AMP-binding enzyme 640 1034 2.3E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS17525 0320af31573bbb4bfdf6a635c16396f9 233 Gene3D G3DSA:3.90.850.10 24 230 3.0E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17525 0320af31573bbb4bfdf6a635c16396f9 233 SUPERFAMILY SSF56529 24 228 1.7E-70 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17525 0320af31573bbb4bfdf6a635c16396f9 233 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 227 3.3E-49 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 SUPERFAMILY SSF53748 11 402 3.42E-150 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 Gene3D G3DSA:3.40.50.1260 12 185 5.4E-72 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 39 61 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 116 131 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 144 166 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 356 367 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PRINTS PR00477 Phosphoglycerate kinase family signature 18 34 9.6E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 Gene3D G3DSA:3.40.50.1270 186 391 2.0E-78 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 23 33 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 13 403 39.912 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 Pfam PF00162 Phosphoglycerate kinase 15 393 3.0E-147 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS04150 0d7568160c530f70812a094757df9f71 404 PIRSF PIRSF000724 6 404 2.1E-147 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 SUPERFAMILY SSF51735 7 258 2.06E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 Pfam PF00106 short chain dehydrogenase 8 198 7.4E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.3E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.3E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.3E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.3E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.3E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27740 dd7d1592ba61d0c3a73ca44605e81809 270 Gene3D G3DSA:3.40.50.720 2 259 8.7E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 SUPERFAMILY SSF54913 1 112 1.46E-44 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 PIRSF PIRSF039144 1 112 1.3E-53 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 Gene3D G3DSA:3.30.70.120 1 112 1.9E-49 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 PRINTS PR00340 P-II protein signature 23 41 6.3E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 PRINTS PR00340 P-II protein signature 2 17 6.3E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 PRINTS PR00340 P-II protein signature 52 75 6.3E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 PRINTS PR00340 P-II protein signature 83 103 6.3E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.2E-43 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS08565 71b7c0bd77afc024d527f6d5e3e4c12d 112 SMART SM00938 4 105 6.7E-65 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK95_RS23610 33f7787ee71386aba57773f802d89e06 540 SUPERFAMILY SSF56801 46 488 1.7E-34 T 06-07-2017 CAK95_RS23610 33f7787ee71386aba57773f802d89e06 540 Pfam PF00501 AMP-binding enzyme 55 355 2.6E-20 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS23610 33f7787ee71386aba57773f802d89e06 540 Gene3D G3DSA:3.40.50.980 49 169 1.0E-19 T 06-07-2017 CAK95_RS23610 33f7787ee71386aba57773f802d89e06 540 Gene3D G3DSA:3.40.50.980 241 332 9.3E-7 T 06-07-2017 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 66 173 1.3E-23 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 147 163 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 29 180 39.367 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 SUPERFAMILY SSF56770 38 181 5.63E-65 T 06-07-2017 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 Gene3D G3DSA:3.40.50.700 52 177 3.6E-33 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22830 8ea7c3acd8b506392d252a7db740ff04 187 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 40 181 2.1E-72 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS20550 d9a599b1d4cb25ef8bb4b7e1ccfd60d0 289 Pfam PF00561 alpha/beta hydrolase fold 28 269 1.1E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20550 d9a599b1d4cb25ef8bb4b7e1ccfd60d0 289 SUPERFAMILY SSF53474 5 284 6.01E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20550 d9a599b1d4cb25ef8bb4b7e1ccfd60d0 289 Gene3D G3DSA:3.40.50.1820 5 284 2.3E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 SMART SM00347 46 147 5.4E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 Pfam PF12802 MarR family 52 111 2.1E-12 T 06-07-2017 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 SUPERFAMILY SSF46785 20 158 6.95E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09915 9ce70d6cc43c8a5a4dc425bcabab6801 171 Gene3D G3DSA:1.10.10.10 16 157 4.6E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 Pfam PF01124 MAPEG family 6 120 6.9E-16 T 06-07-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 PRINTS PR00488 Five-lipoxygenase activating protein signature 100 121 3.4E-7 T 06-07-2017 IPR001446 5-lipoxygenase-activating protein GO:0006691|GO:0008047|GO:0016021 CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 PRINTS PR00488 Five-lipoxygenase activating protein signature 61 80 3.4E-7 T 06-07-2017 IPR001446 5-lipoxygenase-activating protein GO:0006691|GO:0008047|GO:0016021 CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 PRINTS PR00488 Five-lipoxygenase activating protein signature 41 60 3.4E-7 T 06-07-2017 IPR001446 5-lipoxygenase-activating protein GO:0006691|GO:0008047|GO:0016021 CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 PRINTS PR00488 Five-lipoxygenase activating protein signature 81 99 3.4E-7 T 06-07-2017 IPR001446 5-lipoxygenase-activating protein GO:0006691|GO:0008047|GO:0016021 CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 SUPERFAMILY SSF161084 3 127 1.57E-41 T 06-07-2017 CAK95_RS21600 bca55354706b23c27ba40c20c7ade9b9 128 Gene3D G3DSA:1.20.120.550 4 127 8.1E-43 T 06-07-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CAK95_RS28630 5b11662ffd32ec9760aea6bfe88dde53 411 SUPERFAMILY SSF51556 55 367 6.32E-66 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS28630 5b11662ffd32ec9760aea6bfe88dde53 411 Gene3D G3DSA:2.30.40.10 19 69 4.5E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS28630 5b11662ffd32ec9760aea6bfe88dde53 411 SUPERFAMILY SSF51338 5 64 9.56E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS28630 5b11662ffd32ec9760aea6bfe88dde53 411 Pfam PF07969 Amidohydrolase family 43 397 5.8E-24 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS28630 5b11662ffd32ec9760aea6bfe88dde53 411 Gene3D G3DSA:3.20.20.140 70 358 1.2E-85 T 06-07-2017 CAK95_RS02915 d769c96c645315a6dd0834747c871c3b 240 SUPERFAMILY SSF52540 8 230 7.5E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02915 d769c96c645315a6dd0834747c871c3b 240 Pfam PF00005 ABC transporter 25 163 2.8E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS02915 d769c96c645315a6dd0834747c871c3b 240 SMART SM00382 34 220 9.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02915 d769c96c645315a6dd0834747c871c3b 240 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS02915 d769c96c645315a6dd0834747c871c3b 240 Gene3D G3DSA:3.40.50.300 10 233 1.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 Gene3D G3DSA:1.10.760.10 617 708 5.7E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SUPERFAMILY SSF46626 605 704 2.04E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 36 574 1.9E-198 T 06-07-2017 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 Pfam PF13360 PQQ-like domain 489 569 1.9E-6 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 Pfam PF13360 PQQ-like domain 83 231 3.4E-17 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 Gene3D G3DSA:2.140.10.10 51 591 1.5E-150 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SMART SM00564 100 131 6.8E-4 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SMART SM00564 196 233 0.0044 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SMART SM00564 514 546 0.0015 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SMART SM00564 150 182 1.2E-7 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 269 290 - T 06-07-2017 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 SUPERFAMILY SSF50998 45 620 3.4E-171 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAK95_RS13910 b42910b2ccd1963ee4d5cd69bfd719fc 716 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 629 701 1.1E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 TIGRFAM TIGR03383 urate_oxi: urate oxidase 4 278 6.1E-90 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PIRSF PIRSF000241 1 279 9.9E-94 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 SUPERFAMILY SSF55620 3 131 3.74E-40 T 06-07-2017 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 Pfam PF01014 Uricase 140 273 7.4E-28 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 Pfam PF01014 Uricase 7 130 3.3E-20 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PRINTS PR00093 Uricase signature 162 174 3.1E-19 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PRINTS PR00093 Uricase signature 9 20 3.1E-19 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PRINTS PR00093 Uricase signature 48 62 3.1E-19 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PRINTS PR00093 Uricase signature 84 97 3.1E-19 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 PRINTS PR00093 Uricase signature 146 162 3.1E-19 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 SUPERFAMILY SSF55620 137 278 3.67E-48 T 06-07-2017 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 Gene3D G3DSA:3.10.270.10 2 278 2.2E-92 T 06-07-2017 CAK95_RS13230 90d194ea90ebb85a5502a3671b537fb1 279 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 176 278 1.0E-20 T 06-07-2017 CAK95_RS12850 9b3c9ff1228d603820954400a74f4e99 239 SUPERFAMILY SSF52499 5 220 1.44E-61 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12850 9b3c9ff1228d603820954400a74f4e99 239 Gene3D G3DSA:3.40.50.850 3 222 2.4E-75 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12850 9b3c9ff1228d603820954400a74f4e99 239 Pfam PF00857 Isochorismatase family 19 210 1.7E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 Gene3D G3DSA:3.40.190.10 176 263 4.1E-15 T 06-07-2017 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 SUPERFAMILY SSF53850 89 297 1.55E-32 T 06-07-2017 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 Pfam PF03466 LysR substrate binding domain 89 285 1.1E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 Gene3D G3DSA:1.10.10.10 1 81 4.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 Gene3D G3DSA:3.40.190.10 90 175 1.4E-11 T 06-07-2017 CAK95_RS14315 91ddb6b4185ab2be39a68dec563aef1f 310 SUPERFAMILY SSF46785 1 85 1.18E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 22 340 34.186 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 37 105 4.9E-21 T 06-07-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 32 338 7.4E-104 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 237 272 5.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 144 177 7.2E-11 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Gene3D G3DSA:2.160.10.10 224 323 2.5E-23 T 06-07-2017 CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 SUPERFAMILY SSF51161 46 330 4.5E-72 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS12805 0cfd43c331bb360fcbd95e14aaeed42b 344 Gene3D G3DSA:2.160.10.10 125 223 7.2E-24 T 06-07-2017 CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 SUPERFAMILY SSF52540 53 285 4.05E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 262 284 6.1E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 ProSitePatterns PS00211 ABC transporters family signature. 186 200 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 SMART SM00382 77 279 5.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 53 289 8.8E-109 T 06-07-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 Pfam PF00005 ABC transporter 70 214 5.3E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05245 9fad2e91eea6a130447208e7a89910a9 289 Gene3D G3DSA:3.40.50.300 52 280 2.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 Pfam PF01313 Bacterial export proteins, family 3 6 74 4.6E-26 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 84 1.1E-26 T 06-07-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.2E-17 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.2E-17 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.2E-17 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAK95_RS18290 3e9a664cdcae703e13b7e6e8037438dc 88 PIRSF PIRSF004669 1 87 4.0E-26 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 Pfam PF07690 Major Facilitator Superfamily 31 429 3.0E-59 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 Gene3D G3DSA:1.20.1250.20 24 210 4.9E-39 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 4.0E-7 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 4.0E-7 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 4.0E-7 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 Gene3D G3DSA:1.20.1250.20 504 524 6.1E-14 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 Gene3D G3DSA:1.20.1250.20 285 443 6.1E-14 T 06-07-2017 CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 SUPERFAMILY SSF103473 22 212 4.19E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 SUPERFAMILY SSF103473 499 525 4.19E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 SUPERFAMILY SSF103473 268 439 4.19E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS15435 b36fd3dadccf3d94e800edad015a75db 534 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 516 8.1E-124 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 Gene3D G3DSA:1.10.10.10 12 90 7.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 Gene3D G3DSA:3.40.190.10 182 263 2.8E-5 T 06-07-2017 CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 Pfam PF03466 LysR substrate binding domain 92 299 5.8E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 SUPERFAMILY SSF46785 11 115 1.46E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 2.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 SUPERFAMILY SSF53850 94 299 1.71E-41 T 06-07-2017 CAK95_RS17900 9b05e768cc03b5a17346338a447c30d9 302 Gene3D G3DSA:3.40.190.10 96 181 2.4E-26 T 06-07-2017 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SUPERFAMILY SSF53150 133 305 3.4E-35 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 19 902 2.2E-255 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SMART SM00533 308 624 4.7E-75 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Pfam PF05190 MutS family domain IV 456 551 4.9E-22 T 06-07-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Gene3D G3DSA:3.40.1170.10 14 136 1.8E-49 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Gene3D G3DSA:1.10.1420.10 289 496 1.3E-47 T 06-07-2017 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Gene3D G3DSA:3.30.420.110 142 279 3.4E-29 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 731 747 - T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SUPERFAMILY SSF52540 600 840 9.52E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Gene3D G3DSA:3.40.50.300 600 840 7.4E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Pfam PF01624 MutS domain I 19 135 2.0E-41 T 06-07-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Pfam PF05192 MutS domain III 294 592 8.4E-37 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Pfam PF05188 MutS domain II 144 271 8.1E-22 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SUPERFAMILY SSF55271 14 131 4.45E-40 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SUPERFAMILY SSF48334 292 598 6.02E-74 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 SMART SM00534 650 837 1.0E-113 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 18 896 23.461 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 Pfam PF00488 MutS domain V 653 840 2.4E-86 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAK95_RS06250 7fdd1bf9f8f06ed7307f44bc12202738 909 PIRSF PIRSF037677 7 851 5.6E-162 T 06-07-2017 CAK95_RS11070 31390eca09218fe2cef0cbfb4bf2bac5 58 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 3.7E-14 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAK95_RS11070 31390eca09218fe2cef0cbfb4bf2bac5 58 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 54 17.876 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAK95_RS11070 31390eca09218fe2cef0cbfb4bf2bac5 58 PIRSF PIRSF036466 1 55 2.3E-20 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 77 1602 0.0 T 06-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 SUPERFAMILY SSF53223 759 946 8.34E-23 T 06-07-2017 CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 Gene3D G3DSA:3.40.50.720 1106 1182 1.9E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 Gene3D G3DSA:3.40.50.720 948 1059 1.9E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 PIRSF PIRSF036761 10 1608 0.0 T 06-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 SUPERFAMILY SSF51735 1089 1238 1.97E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08495 eafbcf40edc9d96d85aa7b983d5a8293 1608 SUPERFAMILY SSF51735 951 1053 1.97E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 322 9.1E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.5E-8 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 183 3.5E-8 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 3.5E-8 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 SUPERFAMILY SSF51905 1 335 1.4E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 2.3E-11 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 2.3E-11 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.3E-11 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.3E-11 T 06-07-2017 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 Gene3D G3DSA:3.50.50.60 3 101 8.7E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01350 e3739278d8bfcf0a49f1b3563af41f90 434 Gene3D G3DSA:3.50.50.60 102 329 4.3E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SUPERFAMILY SSF81901 207 301 9.15E-8 T 06-07-2017 CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 199 223 22.0 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 53 86 0.0013 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 91 122 0.075 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 159 193 9.1E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 266 292 0.71 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Pfam PF08238 Sel1 repeat 125 158 3.9 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 Gene3D G3DSA:1.25.40.10 36 235 1.5E-38 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SUPERFAMILY SSF81901 37 235 7.59E-35 T 06-07-2017 CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SMART SM00671 262 297 51.0 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SMART SM00671 51 86 2.6E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SMART SM00671 159 194 0.022 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SMART SM00671 87 122 3.5E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS22755 4e9c68d74a8cefea0dfe617d557fea7a 314 SMART SM00671 123 158 61.0 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS13115 8b55de2f4db83fef412a59caa34fea28 167 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 29 160 5.2E-26 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 SMART SM00388 201 267 1.7E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 SMART SM00387 305 420 2.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 266 2.0E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 SUPERFAMILY SSF55874 268 420 1.31E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 419 6.2E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 Gene3D G3DSA:3.30.565.10 273 419 2.5E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS06335 95b6d2cf62b7ae7ea0c58d9394714894 436 SUPERFAMILY SSF47384 191 261 1.37E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS25730 9d801fc2d6015f9d9f5b0d355b5603a7 227 SUPERFAMILY SSF52540 18 202 1.75E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25730 9d801fc2d6015f9d9f5b0d355b5603a7 227 Gene3D G3DSA:3.40.50.300 5 153 2.0E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25730 9d801fc2d6015f9d9f5b0d355b5603a7 227 Gene3D G3DSA:1.10.8.60 161 214 3.8E-8 T 06-07-2017 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 Gene3D G3DSA:3.50.50.60 4 183 4.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 Gene3D G3DSA:3.50.50.60 287 354 4.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 SUPERFAMILY SSF51905 4 178 3.08E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 SUPERFAMILY SSF51905 287 364 3.08E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 Pfam PF01494 FAD binding domain 5 175 1.0E-9 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 Pfam PF01494 FAD binding domain 297 350 8.0E-7 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 SUPERFAMILY SSF54373 183 291 1.73E-29 T 06-07-2017 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.9E-18 T 06-07-2017 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 1.9E-18 T 06-07-2017 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 1.9E-18 T 06-07-2017 CAK95_RS08410 ae82aa8de7e7dcff08431d7c4eeffb25 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.9E-18 T 06-07-2017 CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 Pfam PF02515 CoA-transferase family III 16 403 1.7E-98 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 12 427 63.461 T 06-07-2017 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 SUPERFAMILY SSF89796 14 427 1.96E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 Gene3D G3DSA:3.40.50.10540 337 429 7.7E-104 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 Gene3D G3DSA:3.40.50.10540 14 226 7.7E-104 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 14 426 8.9E-218 T 06-07-2017 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 CAK95_RS12755 3ae954b35a5d5bf8f8abd28715a5b807 437 Gene3D G3DSA:3.30.1540.10 256 336 9.0E-26 T 06-07-2017 CAK95_RS20595 afa06ade8e23963add1219713de17204 395 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 378 1.1E-44 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS20595 afa06ade8e23963add1219713de17204 395 SUPERFAMILY SSF55073 226 380 1.96E-48 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS20595 afa06ade8e23963add1219713de17204 395 SMART SM00267 210 382 9.9E-56 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS20595 afa06ade8e23963add1219713de17204 395 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 220 380 2.0E-47 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS20595 afa06ade8e23963add1219713de17204 395 Gene3D G3DSA:3.30.70.270 223 380 2.2E-54 T 06-07-2017 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 232 387 32.681 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 226 9.6E-61 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 225 2.0E-65 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Pfam PF02542 YgbB family 232 385 2.0E-57 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 SUPERFAMILY SSF69765 232 386 1.83E-60 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 266 281 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 SUPERFAMILY SSF53448 5 226 1.58E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 233 385 9.0E-60 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Gene3D G3DSA:3.90.550.10 4 227 1.8E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 3 388 42.685 T 06-07-2017 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 228 27.893 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 Gene3D G3DSA:3.30.1330.50 231 386 2.5E-64 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK95_RS23240 7f9a1349618a4395a31ffdf7926a408b 390 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 101 108 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK95_RS26495 67b0e20b7c80847c4055098255a3f717 335 Pfam PF13379 NMT1-like family 26 265 2.9E-14 T 06-07-2017 CAK95_RS26495 67b0e20b7c80847c4055098255a3f717 335 Gene3D G3DSA:3.40.190.10 118 198 7.6E-12 T 06-07-2017 CAK95_RS26495 67b0e20b7c80847c4055098255a3f717 335 SUPERFAMILY SSF53850 26 255 7.82E-24 T 06-07-2017 CAK95_RS12885 205251717f56bff39fb0b6eaced6b6f2 291 Pfam PF00950 ABC 3 transport family 15 273 1.2E-53 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAK95_RS12885 205251717f56bff39fb0b6eaced6b6f2 291 SUPERFAMILY SSF81345 12 270 1.83E-21 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 334 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.4E-41 T 06-07-2017 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 Gene3D G3DSA:3.50.50.60 13 189 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 Gene3D G3DSA:3.50.50.60 271 356 1.5E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 Pfam PF01494 FAD binding domain 13 348 3.0E-77 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 SUPERFAMILY SSF51905 12 184 1.53E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00690 c51e1ca6f4affb350b9643b5bd6fea7b 535 SUPERFAMILY SSF51905 270 384 1.53E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10795 9af57c828d5cb5b329c8379c63191454 488 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 42 488 1.7E-130 T 06-07-2017 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 CAK95_RS10795 9af57c828d5cb5b329c8379c63191454 488 Pfam PF13727 CoA-binding domain 85 262 1.0E-15 T 06-07-2017 CAK95_RS10795 9af57c828d5cb5b329c8379c63191454 488 Pfam PF02397 Bacterial sugar transferase 298 482 1.1E-54 T 06-07-2017 IPR003362 Bacterial sugar transferase CAK95_RS10795 9af57c828d5cb5b329c8379c63191454 488 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 38 488 7.0E-121 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 Gene3D G3DSA:3.90.1030.10 1 117 1.9E-51 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 SUPERFAMILY SSF64263 1 119 1.57E-51 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 9.3E-45 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 Pfam PF01196 Ribosomal protein L17 20 116 7.7E-37 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21390 7b15b6a7860b9e936ee3be578f01541d 140 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.227 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21465 cc3276b386e88f3b3497a99d428938b8 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 137 1.1E-22 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS21465 cc3276b386e88f3b3497a99d428938b8 153 Gene3D G3DSA:3.30.530.20 3 146 1.6E-29 T 06-07-2017 IPR023393 START-like domain CAK95_RS21465 cc3276b386e88f3b3497a99d428938b8 153 SUPERFAMILY SSF55961 1 143 2.27E-33 T 06-07-2017 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 SUPERFAMILY SSF116842 7 72 2.35E-19 T 06-07-2017 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 Gene3D G3DSA:1.10.287.1040 8 74 1.3E-23 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 15.062 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 10 54 3.0E-14 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 14 68 1.6E-21 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS15925 0ae3a5694872aa966d96e36b71b66bb7 83 Pfam PF02609 Exonuclease VII small subunit 14 65 3.2E-17 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS09600 167ef005d49a46707c5f33c4c9fb4be0 431 Gene3D G3DSA:3.90.230.10 193 426 1.9E-41 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS09600 167ef005d49a46707c5f33c4c9fb4be0 431 Pfam PF00557 Metallopeptidase family M24 203 411 9.2E-32 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS09600 167ef005d49a46707c5f33c4c9fb4be0 431 SUPERFAMILY SSF55920 195 423 7.59E-44 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS17995 a4422408638cbd5f7114b83163fe2d20 689 Pfam PF01757 Acyltransferase family 12 334 7.3E-26 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 Pfam PF01381 Helix-turn-helix 11 64 4.2E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 Pfam PF00717 Peptidase S24-like 133 178 1.1E-5 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 SUPERFAMILY SSF47413 3 67 2.28E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 Gene3D G3DSA:2.10.109.10 118 219 2.0E-13 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 ProSitePatterns PS00501 Signal peptidases I serine active site. 136 143 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 SUPERFAMILY SSF51306 116 218 7.19E-16 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 Gene3D G3DSA:1.10.260.40 3 65 1.7E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02985 fccfb5ca51e4a89ed5c5ef542f9bd66d 220 SMART SM00530 8 64 1.5E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS25540 da29b6c8afd368ccdd0bb92514bec804 333 SUPERFAMILY SSF53474 60 330 3.08E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25540 da29b6c8afd368ccdd0bb92514bec804 333 Gene3D G3DSA:3.40.50.1820 61 331 5.4E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25540 da29b6c8afd368ccdd0bb92514bec804 333 Pfam PF07859 alpha/beta hydrolase fold 93 298 4.7E-30 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS25540 da29b6c8afd368ccdd0bb92514bec804 333 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 164 176 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 SUPERFAMILY SSF51905 2 290 2.59E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 SUPERFAMILY SSF51905 474 533 2.59E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 Gene3D G3DSA:3.50.50.60 468 533 4.2E-127 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 Gene3D G3DSA:3.50.50.60 4 127 4.2E-127 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 Gene3D G3DSA:3.50.50.60 189 315 4.2E-127 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 SUPERFAMILY SSF54373 292 475 1.47E-53 T 06-07-2017 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 Pfam PF05199 GMC oxidoreductase 389 525 4.9E-38 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 Pfam PF00732 GMC oxidoreductase 7 297 2.0E-90 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS09375 707d76dcb23f45a070f13f48b5fabcba 544 PIRSF PIRSF000137 1 540 6.1E-149 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK95_RS06395 94827666309514005557c75202491630 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 2.0E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 Gene3D G3DSA:1.10.540.10 4 117 3.3E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 1.7E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 SUPERFAMILY SSF56645 4 244 1.31E-66 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 Gene3D G3DSA:2.40.110.10 120 220 2.8E-30 T 06-07-2017 CAK95_RS06395 94827666309514005557c75202491630 386 SUPERFAMILY SSF47203 229 384 1.35E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 218 1.3E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS06395 94827666309514005557c75202491630 386 Gene3D G3DSA:1.20.140.10 221 385 4.3E-56 T 06-07-2017 CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 Gene3D G3DSA:1.10.600.10 10 275 9.5E-70 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 SUPERFAMILY SSF48576 13 278 1.87E-67 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 125 140 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 Pfam PF00494 Squalene/phytoene synthase 16 266 1.2E-61 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 155 180 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAK95_RS04485 7f4c83c851a5131072c9dc4fdf5660ae 279 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 15 278 2.6E-98 T 06-07-2017 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CAK95_RS05045 be534aeb98004115fa0414d0f08c5611 264 Gene3D G3DSA:3.40.50.1110 53 256 1.9E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05045 be534aeb98004115fa0414d0f08c5611 264 SUPERFAMILY SSF52266 55 255 2.14E-21 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05045 be534aeb98004115fa0414d0f08c5611 264 Pfam PF04311 Protein of unknown function (DUF459) 48 249 4.3E-42 T 06-07-2017 IPR007407 Protein of unknown function DUF459 CAK95_RS10040 ae0763cf16af80adaf48b082774aa749 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 271 2.4E-19 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS10040 ae0763cf16af80adaf48b082774aa749 363 Gene3D G3DSA:2.40.50.100 73 106 1.1E-7 T 06-07-2017 CAK95_RS10040 ae0763cf16af80adaf48b082774aa749 363 Gene3D G3DSA:2.40.50.100 167 189 1.1E-7 T 06-07-2017 CAK95_RS10040 ae0763cf16af80adaf48b082774aa749 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 48 352 2.2E-47 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS10040 ae0763cf16af80adaf48b082774aa749 363 SUPERFAMILY SSF111369 62 278 3.53E-25 T 06-07-2017 CAK95_RS04200 c9eccadf1c942eaa35ff665d0194bd2d 340 SUPERFAMILY SSF103088 203 336 2.88E-28 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS04200 c9eccadf1c942eaa35ff665d0194bd2d 340 Pfam PF00691 OmpA family 225 331 9.7E-20 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS04200 c9eccadf1c942eaa35ff665d0194bd2d 340 Gene3D G3DSA:3.30.1330.60 211 338 2.5E-31 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 166 732 8.8E-157 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.90.1170.50 17 138 4.5E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 35 149 5.6E-27 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 474 641 1.2E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 SUPERFAMILY SSF54665 18 172 4.19E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 194 301 3.7E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 SMART SM01008 35 150 3.5E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 139 193 3.2E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 303 380 3.2E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 647 796 8.4E-58 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 Gene3D G3DSA:3.30.365.10 382 473 8.4E-58 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS16215 620a6dfb63ca54fcfe60f5a02ac7b381 798 SUPERFAMILY SSF56003 142 795 8.24E-184 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 SUPERFAMILY SSF46785 2 85 7.24E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 Gene3D G3DSA:3.40.190.10 179 264 1.9E-27 T 06-07-2017 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 Pfam PF03466 LysR substrate binding domain 87 295 4.0E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 Gene3D G3DSA:3.40.190.10 88 178 3.6E-25 T 06-07-2017 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 SUPERFAMILY SSF53850 88 296 7.96E-35 T 06-07-2017 CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 Gene3D G3DSA:1.10.10.10 2 79 4.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02110 3d779b4356f57b011bf983acc964d188 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 Gene3D G3DSA:1.10.10.60 215 249 9.7E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 Pfam PF12833 Helix-turn-helix domain 234 314 2.9E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 SUPERFAMILY SSF51215 58 142 6.15E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 SUPERFAMILY SSF46689 264 316 1.25E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 Pfam PF14525 AraC-binding-like domain 19 192 2.4E-33 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 SMART SM00342 228 313 6.2E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS03840 30491152e819b2de2a1a8eadf5ecbec9 324 Gene3D G3DSA:1.10.10.60 263 315 3.9E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS10085 3f8667c1ffc6ca314dc209360d281a26 323 SUPERFAMILY SSF56281 71 307 1.31E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10085 3f8667c1ffc6ca314dc209360d281a26 323 Gene3D G3DSA:3.60.15.10 103 307 4.0E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10085 3f8667c1ffc6ca314dc209360d281a26 323 Pfam PF00753 Metallo-beta-lactamase superfamily 105 168 1.3E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS10085 3f8667c1ffc6ca314dc209360d281a26 323 SMART SM00849 103 303 1.1E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 Pfam PF01575 MaoC like domain 15 123 4.5E-10 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 PIRSF PIRSF021494 1 349 6.3E-133 T 06-07-2017 IPR016790 Thiol ester hydratase, Rv0216, predicted KEGG: 00630+4.2.1.148|KEGG: 00660+4.2.1.148|KEGG: 00720+4.2.1.148|MetaCyc: PWY-5741|MetaCyc: PWY-5744|MetaCyc: PWY-6728 CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 Gene3D G3DSA:3.10.129.10 187 349 1.0E-27 T 06-07-2017 IPR029069 HotDog domain CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 Gene3D G3DSA:3.10.129.10 3 151 1.2E-34 T 06-07-2017 IPR029069 HotDog domain CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 SUPERFAMILY SSF54637 190 349 7.85E-32 T 06-07-2017 IPR029069 HotDog domain CAK95_RS07820 bbf825341bd5b9a568caabd0402891e9 349 SUPERFAMILY SSF54637 1 151 1.82E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 SUPERFAMILY SSF53474 1 258 4.65E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 15 258 5.8E-84 T 06-07-2017 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 4.4E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.4E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 4.4E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 4.4E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 Gene3D G3DSA:3.40.50.1820 2 258 4.2E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20335 a847ed9b75640cafaf05412bcc5c3d72 259 Pfam PF00561 alpha/beta hydrolase fold 23 245 1.1E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 Pfam PF04079 Segregation and condensation complex subunit ScpB 34 188 2.7E-49 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 Gene3D G3DSA:1.10.10.10 32 98 6.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 SUPERFAMILY SSF46785 105 180 5.07E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 Gene3D G3DSA:1.10.10.10 105 180 2.3E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 34 199 3.1E-30 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAK95_RS23925 e942f6ae0f56c6689552244b440284cb 242 SUPERFAMILY SSF46785 30 100 3.99E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 Gene3D G3DSA:2.60.120.260 382 600 5.7E-40 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 SMART SM00939 336 593 2.0E-50 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 Gene3D G3DSA:3.40.50.1820 272 381 1.5E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 Gene3D G3DSA:3.40.50.1820 30 176 1.5E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 SUPERFAMILY SSF53474 19 372 1.2E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 SUPERFAMILY SSF49785 364 598 5.95E-35 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 349 592 3.1E-36 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 41 324 3.3E-29 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 37 386 1.1E-55 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK95_RS14870 d878583c71f32c67234b4ee47d29bd3d 605 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 412 598 3.2E-19 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 46.256 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 1.5E-22 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 SUPERFAMILY SSF54211 1 181 2.13E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 3.0E-111 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 Gene3D G3DSA:3.30.230.70 9 235 9.2E-29 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 Pfam PF03725 3' exoribonuclease family, domain 2 158 224 2.1E-10 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS08885 9fd69bd8641dbfcbd5e494de1c926754 237 SUPERFAMILY SSF55666 155 235 7.2E-23 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK95_RS01870 f0bc8da6882e516d2c9b6c07b4f08cd7 203 Pfam PF03734 L,D-transpeptidase catalytic domain 75 202 2.0E-18 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS01870 f0bc8da6882e516d2c9b6c07b4f08cd7 203 Gene3D G3DSA:2.40.440.10 69 202 3.2E-36 T 06-07-2017 CAK95_RS01870 f0bc8da6882e516d2c9b6c07b4f08cd7 203 SUPERFAMILY SSF141523 69 202 6.54E-34 T 06-07-2017 CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 Gene3D G3DSA:1.20.120.530 81 214 1.6E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 9.8E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 Gene3D G3DSA:1.10.10.10 9 78 4.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 SMART SM00345 19 77 1.1E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 SMART SM00895 87 209 6.0E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 SUPERFAMILY SSF46785 15 81 1.49E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 Pfam PF07729 FCD domain 87 208 5.1E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27660 a032174b8cf2023612bce9fcd8337eca 247 SUPERFAMILY SSF48008 83 213 8.63E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 Gene3D G3DSA:3.40.50.300 3 215 8.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 26 254 1.9E-91 T 06-07-2017 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 SMART SM00382 34 216 2.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 Pfam PF00005 ABC transporter 26 166 6.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 SUPERFAMILY SSF52540 6 225 3.55E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28330 f829e1d43ca863b51c24e84a305aa0d1 299 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28435 9d081f5fa5f94753c6b867ad7c6a2b72 631 Gene3D G3DSA:3.40.390.10 379 455 1.8E-4 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK95_RS28435 9d081f5fa5f94753c6b867ad7c6a2b72 631 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 42 626 2.7E-205 T 06-07-2017 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 CAK95_RS28435 9d081f5fa5f94753c6b867ad7c6a2b72 631 Pfam PF01432 Peptidase family M3 233 610 2.4E-37 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 CAK95_RS28435 9d081f5fa5f94753c6b867ad7c6a2b72 631 SUPERFAMILY SSF55486 37 612 2.2E-114 T 06-07-2017 CAK95_RS28435 9d081f5fa5f94753c6b867ad7c6a2b72 631 Pfam PF08439 Oligopeptidase F 150 218 1.9E-19 T 06-07-2017 IPR013647 Oligopeptidase F, N-terminal domain CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Gene3D G3DSA:3.40.190.10 176 276 3.6E-29 T 06-07-2017 CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 6.2E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 SUPERFAMILY SSF53850 94 302 2.9E-38 T 06-07-2017 CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 SUPERFAMILY SSF46785 8 88 1.41E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Gene3D G3DSA:3.40.190.10 94 175 2.7E-24 T 06-07-2017 CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Gene3D G3DSA:3.40.190.10 280 307 2.7E-24 T 06-07-2017 CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Gene3D G3DSA:1.10.10.10 6 88 2.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09000 8a46de3e8883f69b11b3116eb429aa2e 322 Pfam PF03466 LysR substrate binding domain 100 305 2.0E-22 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 Gene3D G3DSA:1.10.1040.10 179 301 1.7E-31 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 SUPERFAMILY SSF48179 181 301 8.84E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 299 6.6E-72 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 Gene3D G3DSA:3.40.50.720 1 176 4.6E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 SUPERFAMILY SSF51735 1 178 1.01E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 3.3E-36 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS01875 0cabd9b22321534b7c43e0ac2959ccae 307 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 300 1.9E-25 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 Pfam PF03466 LysR substrate binding domain 92 296 5.3E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 Gene3D G3DSA:3.40.190.10 93 176 1.6E-4 T 06-07-2017 CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 Gene3D G3DSA:3.40.190.10 177 264 1.7E-24 T 06-07-2017 CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 SUPERFAMILY SSF53850 90 299 8.14E-40 T 06-07-2017 CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 SUPERFAMILY SSF46785 4 87 5.44E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15275 114917cd8cec295b864c2b3442fc8798 311 Gene3D G3DSA:1.10.10.10 3 84 7.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17955 45d28b9af8dec7d74e1001bd30f3be6f 264 Pfam PF00149 Calcineurin-like phosphoesterase 9 209 5.6E-13 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS17955 45d28b9af8dec7d74e1001bd30f3be6f 264 SUPERFAMILY SSF56300 6 230 4.27E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS17955 45d28b9af8dec7d74e1001bd30f3be6f 264 Gene3D G3DSA:3.60.21.10 190 246 4.3E-34 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS17955 45d28b9af8dec7d74e1001bd30f3be6f 264 Gene3D G3DSA:3.60.21.10 10 128 4.3E-34 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS21795 da6e10663cdd4eda2786628bfc7733b4 227 Pfam PF04654 Protein of unknown function, DUF599 11 219 6.0E-60 T 06-07-2017 IPR006747 Protein of unknown function DUF599 CAK95_RS24075 bb84b7118e65716f9fa038f12a3d394a 390 Gene3D G3DSA:1.20.1250.20 205 383 9.1E-14 T 06-07-2017 CAK95_RS24075 bb84b7118e65716f9fa038f12a3d394a 390 Pfam PF07690 Major Facilitator Superfamily 2 338 6.1E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS24075 bb84b7118e65716f9fa038f12a3d394a 390 SUPERFAMILY SSF103473 3 381 2.88E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS24075 bb84b7118e65716f9fa038f12a3d394a 390 Gene3D G3DSA:1.20.1250.20 15 177 8.7E-25 T 06-07-2017 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Gene3D G3DSA:3.40.50.80 211 339 2.5E-40 T 06-07-2017 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Gene3D G3DSA:2.40.30.10 112 203 2.4E-18 T 06-07-2017 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 SUPERFAMILY SSF63380 111 203 2.87E-18 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Pfam PF00970 Oxidoreductase FAD-binding domain 114 203 1.1E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 SUPERFAMILY SSF52343 209 339 9.56E-39 T 06-07-2017 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 248 3.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 214 233 3.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 306 314 3.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 155 162 3.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 306 314 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 207 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 239 248 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 214 233 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 155 162 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 138 150 5.9E-21 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Gene3D G3DSA:3.10.20.30 5 97 5.3E-22 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 SUPERFAMILY SSF54292 8 97 9.57E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Pfam PF00175 Oxidoreductase NAD-binding domain 216 319 1.6E-19 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS03310 fb6420afc51bd3974dab2cde3755bc1a 342 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 89 2.9E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS22005 4db8e0ebab9b6b2f6698bce04d67a84f 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 148 2.4E-37 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS22005 4db8e0ebab9b6b2f6698bce04d67a84f 155 Gene3D G3DSA:3.30.1330.40 4 154 1.5E-61 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS22005 4db8e0ebab9b6b2f6698bce04d67a84f 155 SUPERFAMILY SSF55298 5 154 1.01E-51 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 Pfam PF08402 TOBE domain 294 365 5.1E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 Gene3D G3DSA:3.40.50.300 24 257 3.8E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 Pfam PF00005 ABC transporter 43 186 6.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 SUPERFAMILY SSF50331 262 367 8.16E-10 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 SMART SM00382 51 236 8.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23920 492f806c77f0ac4a0cd411de59a68480 370 SUPERFAMILY SSF52540 27 264 2.26E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24515 10b315d507571419eded99f8c16d935f 129 Pfam PF04266 ASCH domain 4 84 1.2E-5 T 06-07-2017 IPR007374 ASCH domain CAK95_RS24515 10b315d507571419eded99f8c16d935f 129 Gene3D G3DSA:2.30.130.30 1 119 2.5E-19 T 06-07-2017 CAK95_RS24515 10b315d507571419eded99f8c16d935f 129 SUPERFAMILY SSF88697 1 39 1.94E-16 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS24515 10b315d507571419eded99f8c16d935f 129 SUPERFAMILY SSF88697 70 120 1.94E-16 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 Gene3D G3DSA:3.40.50.980 345 405 3.2E-22 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 Gene3D G3DSA:3.40.50.980 199 291 3.2E-22 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 Gene3D G3DSA:2.30.38.10 412 472 6.2E-15 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 SUPERFAMILY SSF56801 348 620 6.67E-109 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 SUPERFAMILY SSF56801 9 296 6.67E-109 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 Gene3D G3DSA:3.40.50.980 10 198 2.8E-33 T 06-07-2017 CAK95_RS13000 92af145b5f478a5a4a56a1c9a5f828aa 656 Pfam PF00501 AMP-binding enzyme 17 478 1.2E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 SUPERFAMILY SSF46785 5 114 1.27E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 Gene3D G3DSA:3.40.190.10 92 182 7.0E-21 T 06-07-2017 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 Pfam PF03466 LysR substrate binding domain 93 300 3.1E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.5E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 Gene3D G3DSA:3.40.190.10 183 267 2.6E-17 T 06-07-2017 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 SUPERFAMILY SSF53850 94 300 8.69E-40 T 06-07-2017 CAK95_RS04305 00188fdb5bc08a8c0d9b66dec802dbff 303 Gene3D G3DSA:1.10.10.10 6 91 3.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03265 18fd4385fd8940e231b5b92a9064e49c 364 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 294 8.5E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS12290 8bd4518c6e98cbc0a6a6715422ecf32b 157 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12290 8bd4518c6e98cbc0a6a6715422ecf32b 157 Gene3D G3DSA:3.40.30.10 76 154 4.0E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12290 8bd4518c6e98cbc0a6a6715422ecf32b 157 PIRSF PIRSF000216 2 157 4.8E-49 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12290 8bd4518c6e98cbc0a6a6715422ecf32b 157 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 13 155 1.1E-43 T 06-07-2017 CAK95_RS12290 8bd4518c6e98cbc0a6a6715422ecf32b 157 SUPERFAMILY SSF52833 4 155 2.09E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23165 683523c54949247473e767eb0c4f6faa 341 SUPERFAMILY SSF52518 17 338 1.62E-108 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS23165 683523c54949247473e767eb0c4f6faa 341 Pfam PF00676 Dehydrogenase E1 component 32 329 2.8E-107 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAK95_RS23165 683523c54949247473e767eb0c4f6faa 341 Gene3D G3DSA:3.40.50.970 15 339 2.3E-139 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS23165 683523c54949247473e767eb0c4f6faa 341 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 24 337 2.1E-157 T 06-07-2017 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 SUPERFAMILY SSF53223 19 171 2.73E-49 T 06-07-2017 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Pfam PF03949 Malic enzyme, NAD binding domain 175 370 8.7E-21 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Gene3D G3DSA:3.40.50.10380 16 170 3.0E-44 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Pfam PF00390 Malic enzyme, N-terminal domain 29 161 1.0E-22 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 SMART SM00919 173 409 1.9E-141 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 ProSitePatterns PS00331 Malic enzymes signature. 169 185 - T 06-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Gene3D G3DSA:3.40.50.720 171 457 1.5E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09475 05d041850912484b138d69fb8add520a 760 SMART SM01274 28 161 7.5E-74 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 PIRSF PIRSF036684 9 760 0.0 T 06-07-2017 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 SUPERFAMILY SSF51735 173 451 4.55E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Pfam PF01515 Phosphate acetyl/butaryl transferase 439 755 9.4E-91 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 SUPERFAMILY SSF53659 439 757 2.59E-84 T 06-07-2017 CAK95_RS09475 05d041850912484b138d69fb8add520a 760 Gene3D G3DSA:3.40.50.10750 576 731 3.5E-46 T 06-07-2017 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 SUPERFAMILY SSF46894 133 198 2.35E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 SUPERFAMILY SSF52172 6 150 1.85E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 197 1.3E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 Gene3D G3DSA:3.40.50.2300 6 144 1.3E-37 T 06-07-2017 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 SMART SM00448 5 116 3.0E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 Pfam PF00072 Response regulator receiver domain 7 116 7.0E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 SMART SM00421 140 197 9.6E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 Gene3D G3DSA:1.10.10.10 145 198 2.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 2.9E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 2.9E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS16755 f85368af70398e5ed30ed6e8704085ba 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 2.9E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS06090 57aab83c444f45c27674c5d2b55a7d26 456 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 7 453 1.6E-190 T 06-07-2017 IPR010252 Formiminoglutamate deiminase CAK95_RS06090 57aab83c444f45c27674c5d2b55a7d26 456 Gene3D G3DSA:3.20.20.140 56 398 1.9E-68 T 06-07-2017 CAK95_RS06090 57aab83c444f45c27674c5d2b55a7d26 456 Pfam PF01979 Amidohydrolase family 50 427 3.2E-33 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS06090 57aab83c444f45c27674c5d2b55a7d26 456 SUPERFAMILY SSF51338 362 450 1.85E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS06090 57aab83c444f45c27674c5d2b55a7d26 456 SUPERFAMILY SSF51556 52 376 2.56E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS03315 703574edd265ace74205da6eb9100d91 308 Pfam PF12697 Alpha/beta hydrolase family 45 298 8.2E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS03315 703574edd265ace74205da6eb9100d91 308 Gene3D G3DSA:3.40.50.1820 23 306 4.0E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS03315 703574edd265ace74205da6eb9100d91 308 SUPERFAMILY SSF53474 8 305 7.25E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16035 b2ca6fcf78ec753cb8b91e4e1d76d6f9 369 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 17 342 3.1E-20 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS16035 b2ca6fcf78ec753cb8b91e4e1d76d6f9 369 Gene3D G3DSA:3.20.20.210 8 369 9.5E-103 T 06-07-2017 CAK95_RS16035 b2ca6fcf78ec753cb8b91e4e1d76d6f9 369 SUPERFAMILY SSF51726 13 368 3.01E-74 T 06-07-2017 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 493 3.2E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Gene3D G3DSA:2.30.38.10 330 399 1.5E-19 T 06-07-2017 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Pfam PF00501 AMP-binding enzyme 9 409 8.5E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Gene3D G3DSA:3.40.50.980 3 167 2.9E-33 T 06-07-2017 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 SUPERFAMILY SSF56801 2 505 5.36E-117 T 06-07-2017 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Gene3D G3DSA:3.30.300.30 407 504 4.2E-16 T 06-07-2017 CAK95_RS28670 90c523aab64d76ce9248d0f0dd959bb6 510 Gene3D G3DSA:3.40.50.980 168 313 1.6E-26 T 06-07-2017 CAK95_RS02095 5718cb04fd6e2bdf7e262514fbf29903 136 Pfam PF00581 Rhodanese-like domain 8 111 5.4E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS02095 5718cb04fd6e2bdf7e262514fbf29903 136 SMART SM00450 7 119 6.0E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS02095 5718cb04fd6e2bdf7e262514fbf29903 136 SUPERFAMILY SSF52821 4 134 7.6E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS02095 5718cb04fd6e2bdf7e262514fbf29903 136 Gene3D G3DSA:3.40.250.10 3 135 1.1E-36 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS26825 d869ebd582aaaf466d5bd4e6e40cd637 675 Pfam PF00535 Glycosyl transferase family 2 410 588 1.3E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS26825 d869ebd582aaaf466d5bd4e6e40cd637 675 Gene3D G3DSA:3.90.550.10 409 663 1.4E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26825 d869ebd582aaaf466d5bd4e6e40cd637 675 Gene3D G3DSA:3.90.550.10 190 383 4.3E-6 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26825 d869ebd582aaaf466d5bd4e6e40cd637 675 SUPERFAMILY SSF53448 190 383 5.16E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26825 d869ebd582aaaf466d5bd4e6e40cd637 675 SUPERFAMILY SSF53448 397 654 4.22E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS12745 713400c54b085d69888af9582e01f128 247 SMART SM00895 109 234 1.5E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS12745 713400c54b085d69888af9582e01f128 247 SMART SM00345 38 99 4.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12745 713400c54b085d69888af9582e01f128 247 Gene3D G3DSA:1.20.120.530 103 242 7.7E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS12745 713400c54b085d69888af9582e01f128 247 SUPERFAMILY SSF46785 38 122 5.78E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12745 713400c54b085d69888af9582e01f128 247 SUPERFAMILY SSF48008 105 241 1.46E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS12745 713400c54b085d69888af9582e01f128 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 73 9.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12745 713400c54b085d69888af9582e01f128 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 73 89 9.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12745 713400c54b085d69888af9582e01f128 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 37 99 1.8E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12745 713400c54b085d69888af9582e01f128 247 Gene3D G3DSA:1.10.10.10 29 99 6.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12745 713400c54b085d69888af9582e01f128 247 Pfam PF07729 FCD domain 109 232 3.1E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04310 1f88658809574485ad5b53e10bdbe083 182 Gene3D G3DSA:2.40.440.10 47 181 2.1E-35 T 06-07-2017 CAK95_RS04310 1f88658809574485ad5b53e10bdbe083 182 SUPERFAMILY SSF141523 47 181 1.96E-32 T 06-07-2017 CAK95_RS04310 1f88658809574485ad5b53e10bdbe083 182 Pfam PF03734 L,D-transpeptidase catalytic domain 53 180 1.2E-17 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS23915 e653884c34110e7e0ab4f6adb8495368 80 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 1.2E-21 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAK95_RS23915 e653884c34110e7e0ab4f6adb8495368 80 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 61 21.334 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAK95_RS23915 e653884c34110e7e0ab4f6adb8495368 80 Pfam PF02416 mttA/Hcf106 family 4 51 2.9E-12 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAK95_RS28640 0de39d73f1b7ba4222f98d2ed74f63f9 357 SUPERFAMILY SSF55961 119 333 6.87E-31 T 06-07-2017 CAK95_RS28640 0de39d73f1b7ba4222f98d2ed74f63f9 357 Gene3D G3DSA:2.102.10.10 10 128 3.5E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS28640 0de39d73f1b7ba4222f98d2ed74f63f9 357 SUPERFAMILY SSF50022 5 127 1.7E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS28640 0de39d73f1b7ba4222f98d2ed74f63f9 357 Pfam PF00355 Rieske [2Fe-2S] domain 13 93 8.3E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS18580 e490980b1759c41ef9c7c8edcd8e4c9e 409 PIRSF PIRSF000524 7 407 1.5E-118 T 06-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CAK95_RS18580 e490980b1759c41ef9c7c8edcd8e4c9e 409 Gene3D G3DSA:3.40.640.10 24 281 4.0E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS18580 e490980b1759c41ef9c7c8edcd8e4c9e 409 Gene3D G3DSA:3.90.1150.10 282 392 2.8E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS18580 e490980b1759c41ef9c7c8edcd8e4c9e 409 Pfam PF00266 Aminotransferase class-V 35 355 3.3E-29 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS18580 e490980b1759c41ef9c7c8edcd8e4c9e 409 SUPERFAMILY SSF53383 11 390 3.34E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS08675 9cb5d1d55ccf5568775aeee6eb5b983d 107 Gene3D G3DSA:3.30.1200.10 9 100 2.5E-22 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK95_RS08675 9cb5d1d55ccf5568775aeee6eb5b983d 107 SMART SM01152 12 93 1.0E-30 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK95_RS08675 9cb5d1d55ccf5568775aeee6eb5b983d 107 Hamap MF_00634 UPF0235 protein YggU [yggU]. 12 104 17.86 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK95_RS08675 9cb5d1d55ccf5568775aeee6eb5b983d 107 SUPERFAMILY SSF69786 9 102 2.09E-20 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK95_RS08675 9cb5d1d55ccf5568775aeee6eb5b983d 107 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 15 91 1.1E-21 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK95_RS20790 14d2c2ad87267af3d5f14fb4e6798f77 305 Pfam PF01794 Ferric reductase like transmembrane component 59 172 2.1E-14 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain CAK95_RS16725 d7579b9155ec6140d58cfd46d5e59de6 555 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 278 333 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS16725 d7579b9155ec6140d58cfd46d5e59de6 555 Gene3D G3DSA:1.20.210.10 91 543 9.4E-62 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS16725 d7579b9155ec6140d58cfd46d5e59de6 555 SUPERFAMILY SSF81442 84 542 8.9E-117 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS16725 d7579b9155ec6140d58cfd46d5e59de6 555 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 89 518 1.0E-110 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS16725 d7579b9155ec6140d58cfd46d5e59de6 555 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 82 538 5.9E-219 T 06-07-2017 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS23205 83853f1358641b341d1402294cd88354 330 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 328 1.1E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23205 83853f1358641b341d1402294cd88354 330 SMART SM00387 234 329 1.5E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23205 83853f1358641b341d1402294cd88354 330 SUPERFAMILY SSF55874 203 326 1.44E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23205 83853f1358641b341d1402294cd88354 330 Gene3D G3DSA:3.30.565.10 192 326 4.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS23205 83853f1358641b341d1402294cd88354 330 Pfam PF07568 Histidine kinase 141 212 1.5E-17 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CAK95_RS23205 83853f1358641b341d1402294cd88354 330 SMART SM00911 141 228 0.0028 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 83 97 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 SUPERFAMILY SSF50129 14 207 1.43E-43 T 06-07-2017 IPR011032 GroES-like CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 SMART SM00829 25 375 5.8E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 Pfam PF00107 Zinc-binding dehydrogenase 208 327 1.0E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 Gene3D G3DSA:3.40.50.720 202 320 1.6E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 SUPERFAMILY SSF51735 171 341 1.35E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 165 9.6E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS10065 79070399138b2b56a9534206ba3bf57d 388 Gene3D G3DSA:3.90.180.10 10 201 1.3E-48 T 06-07-2017 IPR011032 GroES-like CAK95_RS23955 7707041d30271e3192e8aa4d811a6b9c 110 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 105 7.5E-20 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS23955 7707041d30271e3192e8aa4d811a6b9c 110 Gene3D G3DSA:2.60.300.12 6 100 2.9E-32 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS23955 7707041d30271e3192e8aa4d811a6b9c 110 SUPERFAMILY SSF89360 5 99 1.04E-30 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS23955 7707041d30271e3192e8aa4d811a6b9c 110 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 6 109 3.3E-37 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAK95_RS23955 7707041d30271e3192e8aa4d811a6b9c 110 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Pfam PF00384 Molybdopterin oxidoreductase 279 601 4.3E-64 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 68 2.6E-12 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Gene3D G3DSA:3.40.50.740 279 346 5.2E-52 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Gene3D G3DSA:3.40.50.740 515 629 5.2E-52 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Gene3D G3DSA:3.40.50.740 378 415 5.2E-52 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 635 678 1.7E-15 T 06-07-2017 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Gene3D G3DSA:3.10.20.30 7 55 2.4E-5 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 106 118 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Gene3D G3DSA:3.40.50.1220 439 514 6.9E-5 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 599 6.1E-217 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 91 130 1.8E-17 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 SUPERFAMILY SSF54292 3 68 7.58E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 SMART SM00929 91 131 4.2E-22 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 SUPERFAMILY SSF53706 221 629 1.04E-102 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 SUPERFAMILY SSF54862 84 219 1.84E-37 T 06-07-2017 CAK95_RS22860 20f15c4a2d7d99a295179c93c4d0de3c 692 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 153 163 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS18515 eb6107357a5aae8341fa6231785bf1ad 330 SUPERFAMILY SSF53474 103 311 1.85E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18515 eb6107357a5aae8341fa6231785bf1ad 330 Pfam PF07859 alpha/beta hydrolase fold 113 237 6.5E-11 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS18515 eb6107357a5aae8341fa6231785bf1ad 330 Gene3D G3DSA:3.40.50.1820 74 311 1.7E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18515 eb6107357a5aae8341fa6231785bf1ad 330 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 178 193 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK95_RS01180 266549c601fb7c75291ebc36386dedee 365 Gene3D G3DSA:3.40.1610.10 3 222 3.4E-23 T 06-07-2017 IPR027479 Protein of unknown function DUF917, N-terminal CAK95_RS01180 266549c601fb7c75291ebc36386dedee 365 SUPERFAMILY SSF160991 3 355 4.97E-77 T 06-07-2017 CAK95_RS01180 266549c601fb7c75291ebc36386dedee 365 Pfam PF06032 Protein of unknown function (DUF917) 8 329 2.0E-54 T 06-07-2017 IPR010318 Protein of unknown function DUF917 CAK95_RS01180 266549c601fb7c75291ebc36386dedee 365 Gene3D G3DSA:2.40.390.10 226 346 1.3E-29 T 06-07-2017 IPR024071 Protein of unknown function DUF917, C-terminal CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 SMART SM00244 25 182 3.7E-62 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 SUPERFAMILY SSF117892 56 189 5.62E-43 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 32 54 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 114 131 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 202 225 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 79 100 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 158 176 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 177 198 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 PRINTS PR00721 Stomatin signature 134 157 7.4E-58 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK95_RS25285 34d801f59171363f258ea4ff8e034ab4 252 Pfam PF01145 SPFH domain / Band 7 family 30 198 3.1E-35 T 06-07-2017 IPR001107 Band 7 domain CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 Pfam PF01494 FAD binding domain 6 350 1.7E-65 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 Gene3D G3DSA:3.50.50.60 295 323 1.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 Gene3D G3DSA:3.50.50.60 4 181 1.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 336 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.9E-34 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 Gene3D G3DSA:3.30.9.10 240 294 2.0E-4 T 06-07-2017 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 SUPERFAMILY SSF51905 6 178 8.25E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27685 67b8e2146ca139823eff4cb51885491c 400 SUPERFAMILY SSF51905 272 351 8.25E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 SUPERFAMILY SSF47598 1 43 1.26E-10 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 TIGRFAM TIGR02793 nikR: nickel-responsive transcriptional regulator NikR 2 131 2.1E-58 T 06-07-2017 IPR014160 Nickel-responsive transcriptional regulator NikR, proteobacteria GO:0010045|GO:0016151 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 Gene3D G3DSA:3.30.70.1150 50 132 2.2E-31 T 06-07-2017 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 Hamap MF_00476 Putative nickel-responsive regulator [nikR]. 1 132 27.523 T 06-07-2017 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 Pfam PF08753 NikR C terminal nickel binding domain 54 130 2.2E-26 T 06-07-2017 IPR014864 Transcription factor, NikR, nickel binding C-terminal CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 SUPERFAMILY SSF55021 51 132 3.89E-26 T 06-07-2017 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 42 7.0E-11 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK95_RS20125 5366e52ab97a4730527cd59477fb4e52 145 Gene3D G3DSA:1.10.1220.10 1 44 1.1E-23 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 SMART SM00382 35 233 1.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 PIRSF PIRSF037116 1 262 5.9E-140 T 06-07-2017 IPR012700 Phosphonate C-P lyase system, PhnK CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 8 260 1.4E-115 T 06-07-2017 IPR012700 Phosphonate C-P lyase system, PhnK CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 Gene3D G3DSA:3.40.50.300 6 258 5.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 Pfam PF00005 ABC transporter 27 183 1.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 SUPERFAMILY SSF52540 7 258 3.32E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27905 6664af05c32f081a5b3f9098f003ca01 262 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 413 609 1.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 Pfam PF11812 Domain of unknown function (DUF3333) 21 165 1.2E-47 T 06-07-2017 IPR024573 Domain of unknown function DUF3333 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 Gene3D G3DSA:1.10.3720.10 370 612 2.3E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 Gene3D G3DSA:1.10.3720.10 47 65 2.3E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 SUPERFAMILY SSF161098 389 596 2.22E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05880 1be2614f15830c3c9203a82f2e13846a 613 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 371 610 4.2E-64 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 SUPERFAMILY SSF161098 187 375 2.09E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 389 7.7E-9 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 Gene3D G3DSA:1.10.3720.10 82 155 2.1E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 Gene3D G3DSA:1.10.3720.10 260 389 2.1E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 84 148 4.7E-15 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS24210 a1753db60f72b85222b87181626243b0 394 SUPERFAMILY SSF161098 84 152 5.07E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06700 af807467fc07beb96c408810f792b043 224 Gene3D G3DSA:3.40.30.10 53 218 1.8E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS06700 af807467fc07beb96c408810f792b043 224 SUPERFAMILY SSF52833 48 214 4.93E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS06700 af807467fc07beb96c408810f792b043 224 Pfam PF13462 Thioredoxin 61 214 2.8E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25920 c74abc9f5e0e4a60d97b7cdf7286a777 320 Pfam PF09991 Predicted membrane protein (DUF2232) 14 301 2.4E-15 T 06-07-2017 IPR018710 Protein of unknown function DUF2232 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 Gene3D G3DSA:3.30.1120.10 462 505 2.3E-7 T 06-07-2017 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 Gene3D G3DSA:3.40.720.10 6 109 4.5E-95 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 Gene3D G3DSA:3.40.720.10 147 251 4.5E-95 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 Gene3D G3DSA:3.40.720.10 294 461 4.5E-95 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 SUPERFAMILY SSF53649 6 502 9.01E-114 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS01895 adb73a758a7baed08c28b2e38a0cfafc 548 Pfam PF00884 Sulfatase 6 392 7.6E-52 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS16560 73332e812f8bc4c8f419e09d8eacce3f 436 Gene3D G3DSA:3.40.50.10180 13 250 1.1E-85 T 06-07-2017 CAK95_RS16560 73332e812f8bc4c8f419e09d8eacce3f 436 Gene3D G3DSA:3.40.1480.10 251 432 7.5E-58 T 06-07-2017 IPR007835 MOFRL domain Reactome: R-HSA-70350 CAK95_RS16560 73332e812f8bc4c8f419e09d8eacce3f 436 Pfam PF05161 MOFRL family 316 424 1.7E-32 T 06-07-2017 IPR007835 MOFRL domain Reactome: R-HSA-70350 CAK95_RS16560 73332e812f8bc4c8f419e09d8eacce3f 436 Pfam PF13660 Domain of unknown function (DUF4147) 13 235 2.2E-72 T 06-07-2017 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 CAK95_RS16560 73332e812f8bc4c8f419e09d8eacce3f 436 SUPERFAMILY SSF82544 10 430 2.35E-128 T 06-07-2017 CAK95_RS26145 74fbd688399fa416eef8a84ae346b6cb 116 Gene3D G3DSA:3.40.30.10 2 114 3.5E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS26145 74fbd688399fa416eef8a84ae346b6cb 116 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 112 1.9E-30 T 06-07-2017 IPR006504 Transcriptional regulator Spx/MgsR CAK95_RS26145 74fbd688399fa416eef8a84ae346b6cb 116 SUPERFAMILY SSF52833 2 114 4.02E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS26145 74fbd688399fa416eef8a84ae346b6cb 116 Pfam PF03960 ArsC family 6 112 8.2E-19 T 06-07-2017 IPR006660 Arsenate reductase-like CAK95_RS18650 bad8791465eecefd0fd6914b895d12d8 238 Pfam PF00005 ABC transporter 24 166 4.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS18650 bad8791465eecefd0fd6914b895d12d8 238 Gene3D G3DSA:3.40.50.300 6 228 3.9E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18650 bad8791465eecefd0fd6914b895d12d8 238 SUPERFAMILY SSF52540 8 230 2.15E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18650 bad8791465eecefd0fd6914b895d12d8 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS18650 bad8791465eecefd0fd6914b895d12d8 238 SMART SM00382 33 217 4.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17550 2c0dba7690dce0af4cea1df36617a0d9 357 SUPERFAMILY SSF53756 63 355 3.99E-70 T 06-07-2017 CAK95_RS17550 2c0dba7690dce0af4cea1df36617a0d9 357 Gene3D G3DSA:3.40.50.2000 143 331 5.4E-32 T 06-07-2017 CAK95_RS17550 2c0dba7690dce0af4cea1df36617a0d9 357 Pfam PF00534 Glycosyl transferases group 1 173 331 3.6E-36 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS25430 38eb40a38c222d08e9ef535eff2000d1 268 Gene3D G3DSA:1.10.12.10 211 267 9.6E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS25430 38eb40a38c222d08e9ef535eff2000d1 268 SUPERFAMILY SSF52096 25 268 1.34E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25430 38eb40a38c222d08e9ef535eff2000d1 268 Gene3D G3DSA:3.90.226.10 20 207 1.1E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25430 38eb40a38c222d08e9ef535eff2000d1 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 30 265 2.1E-47 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS02030 214a41a65ffb012b4f8bcebf51977aa8 245 Pfam PF01569 PAP2 superfamily 115 230 2.2E-25 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS02030 214a41a65ffb012b4f8bcebf51977aa8 245 Gene3D G3DSA:1.20.144.10 44 231 1.7E-37 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS02030 214a41a65ffb012b4f8bcebf51977aa8 245 SMART SM00014 111 225 3.1E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS02030 214a41a65ffb012b4f8bcebf51977aa8 245 SUPERFAMILY SSF48317 29 231 1.44E-41 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS04235 7490edbd12e34c9442a7657b997126a0 196 SUPERFAMILY SSF46785 1 93 2.82E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04235 7490edbd12e34c9442a7657b997126a0 196 Gene3D G3DSA:1.10.10.10 12 69 2.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04235 7490edbd12e34c9442a7657b997126a0 196 Pfam PF12840 Helix-turn-helix domain 14 67 4.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 Pfam PF00593 TonB dependent receptor 572 804 2.3E-23 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 Gene3D G3DSA:2.40.170.20 280 823 3.8E-71 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 SMART SM00965 83 134 1.4E-7 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 Pfam PF07715 TonB-dependent Receptor Plug Domain 168 277 3.6E-13 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 SUPERFAMILY SSF56935 140 823 1.68E-97 T 06-07-2017 CAK95_RS04865 a6a78f304bbe59173240283fe099cbd9 823 Gene3D G3DSA:2.170.130.10 145 279 3.4E-25 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 Pfam PF00237 Ribosomal protein L22p/L17e 20 119 2.7E-31 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 SUPERFAMILY SSF54843 5 123 5.62E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 25.314 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 2.4E-33 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21290 27db67f91e43b8eb3901869fd94cc2c1 127 Gene3D G3DSA:3.90.470.10 14 123 9.8E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK95_RS16895 d913c77bbb00c3f5f1de6aeed343fed3 167 SMART SM00903 17 163 1.8E-48 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS16895 d913c77bbb00c3f5f1de6aeed343fed3 167 SUPERFAMILY SSF50475 12 164 2.06E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS16895 d913c77bbb00c3f5f1de6aeed343fed3 167 Pfam PF01613 Flavin reductase like domain 17 164 4.5E-37 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS16895 d913c77bbb00c3f5f1de6aeed343fed3 167 Gene3D G3DSA:2.30.110.10 7 163 1.7E-49 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS26305 14106116792e0b6f9721b71631683a9a 264 Pfam PF01381 Helix-turn-helix 11 63 2.0E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS26305 14106116792e0b6f9721b71631683a9a 264 SMART SM00530 10 65 3.9E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS26305 14106116792e0b6f9721b71631683a9a 264 SUPERFAMILY SSF47413 5 64 3.38E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS26305 14106116792e0b6f9721b71631683a9a 264 Gene3D G3DSA:1.10.260.40 7 64 8.1E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 Gene3D G3DSA:1.10.357.10 60 186 4.1E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 SUPERFAMILY SSF46689 2 75 9.23E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 Gene3D G3DSA:1.10.10.60 3 59 1.2E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS26195 98a0a3ec6752df9151f3af30ef6d8c89 194 SUPERFAMILY SSF48498 83 186 1.33E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 103 8.7E-28 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 SMART SM00739 4 31 2.1E-5 T 06-07-2017 IPR005824 KOW CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 Pfam PF00467 KOW motif 7 30 2.1E-5 T 06-07-2017 IPR005824 KOW CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 1.6E-36 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 SUPERFAMILY SSF50104 2 99 3.46E-33 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 Gene3D G3DSA:2.30.30.30 3 92 4.8E-26 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK95_RS21320 5b5974517cc55c5d8e7f7a330e62616c 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 21.11 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 Pfam PF07719 Tetratricopeptide repeat 151 181 3.7E-5 T 06-07-2017 IPR013105 Tetratricopeptide repeat 2 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 SMART SM00028 115 148 0.0021 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 SMART SM00028 149 182 0.11 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 SUPERFAMILY SSF48452 79 185 7.32E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 Pfam PF13432 Tetratricopeptide repeat 88 135 0.0098 T 06-07-2017 CAK95_RS16540 2423a3d1b5c1def1cee36458220051e2 201 Gene3D G3DSA:1.25.40.10 81 183 3.1E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS01855 ae81d38acf0df4227f79d50401eedda2 171 SUPERFAMILY SSF118196 31 169 3.14E-48 T 06-07-2017 IPR023370 TsaA-like domain CAK95_RS01855 ae81d38acf0df4227f79d50401eedda2 171 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 32 162 2.0E-38 T 06-07-2017 IPR023370 TsaA-like domain CAK95_RS01855 ae81d38acf0df4227f79d50401eedda2 171 Pfam PF01980 Uncharacterised protein family UPF0066 47 157 1.6E-31 T 06-07-2017 IPR023370 TsaA-like domain CAK95_RS01855 ae81d38acf0df4227f79d50401eedda2 171 Gene3D G3DSA:2.40.30.70 33 169 1.5E-46 T 06-07-2017 IPR023370 TsaA-like domain CAK95_RS27610 9606864140a211cf90ce2e3d67b0af1c 341 PIRSF PIRSF017082 13 341 2.0E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27610 9606864140a211cf90ce2e3d67b0af1c 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 337 6.4E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27610 9606864140a211cf90ce2e3d67b0af1c 341 SUPERFAMILY SSF53850 133 305 1.47E-13 T 06-07-2017 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 SUPERFAMILY SSF53383 30 392 2.66E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 10 390 5.8E-170 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 PIRSF PIRSF001434 1 393 2.6E-124 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 Gene3D G3DSA:3.40.640.10 8 256 4.5E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 Gene3D G3DSA:3.90.1150.10 258 393 5.5E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 390 6.3E-128 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS26350 b4a618975a9911179e379068cf407bed 393 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 10 391 53.807 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 Pfam PF01343 Peptidase family S49 111 262 1.5E-41 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 Gene3D G3DSA:3.90.226.10 189 265 4.1E-42 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 Gene3D G3DSA:3.90.226.10 35 151 4.1E-42 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 58 260 2.5E-59 T 06-07-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 SUPERFAMILY SSF52096 188 249 2.07E-36 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10940 05aa09c5d80bf543e9c03943e0b25a47 330 SUPERFAMILY SSF52096 54 159 2.07E-36 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22110 ac0940f48e0524fce8628b0586e3722d 259 Pfam PF02517 CAAX protease self-immunity 158 245 1.2E-18 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAK95_RS04885 3dd79b57c5bbd6e3443136b85ee890be 242 SUPERFAMILY SSF52499 16 233 1.31E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS04885 3dd79b57c5bbd6e3443136b85ee890be 242 Gene3D G3DSA:3.40.50.850 14 235 8.9E-58 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS04885 3dd79b57c5bbd6e3443136b85ee890be 242 Pfam PF00857 Isochorismatase family 30 225 1.7E-37 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS08330 2487923d52849ad8735b7abcb15b07ff 353 Pfam PF13379 NMT1-like family 31 278 1.1E-18 T 06-07-2017 CAK95_RS08330 2487923d52849ad8735b7abcb15b07ff 353 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 25 0.0012 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS08330 2487923d52849ad8735b7abcb15b07ff 353 SUPERFAMILY SSF53850 35 257 2.1E-25 T 06-07-2017 CAK95_RS08330 2487923d52849ad8735b7abcb15b07ff 353 Gene3D G3DSA:3.40.190.10 145 256 1.0E-7 T 06-07-2017 CAK95_RS06235 a780d53bedbcdddc8475a6a83c30dfb5 512 Gene3D G3DSA:3.40.920.10 9 210 8.5E-9 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS06235 a780d53bedbcdddc8475a6a83c30dfb5 512 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 206 2.6E-15 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS06235 a780d53bedbcdddc8475a6a83c30dfb5 512 SUPERFAMILY SSF53323 9 211 9.94E-11 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 Gene3D G3DSA:1.10.10.60 2 62 8.7E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 SUPERFAMILY SSF48498 83 192 1.07E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 SUPERFAMILY SSF46689 2 82 1.23E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 Gene3D G3DSA:1.10.357.10 63 193 1.7E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS17390 2db21b8f43be298eb47db399aa0e39fb 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 8.4E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Pfam PF08448 PAS fold 343 453 5.1E-8 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Pfam PF08448 PAS fold 97 201 1.8E-6 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF55785 196 252 9.25E-5 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF55874 522 701 7.2E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Gene3D G3DSA:1.10.287.130 460 518 1.3E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 575 694 2.5E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF55785 88 198 2.62E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00388 466 532 2.5E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00091 337 403 0.084 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00091 212 280 3.4 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00091 86 153 0.013 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00448 731 846 2.2E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF47384 459 529 1.12E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Pfam PF00072 Response regulator receiver domain 733 846 8.3E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Pfam PF00512 His Kinase A (phospho-acceptor) domain 468 530 6.3E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF52172 732 851 1.99E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Gene3D G3DSA:3.30.565.10 519 699 3.3E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SMART SM00387 573 696 1.0E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Gene3D G3DSA:3.30.450.20 88 198 5.2E-11 T 06-07-2017 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 SUPERFAMILY SSF55785 327 447 6.81E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Gene3D G3DSA:3.40.50.2300 730 851 2.0E-32 T 06-07-2017 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 Gene3D G3DSA:3.30.450.20 329 431 3.8E-9 T 06-07-2017 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 693 1.8E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 639 1.8E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 653 1.8E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18305 9d54770525593f17122496d7515ee76c 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 674 1.8E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Pfam PF13180 PDZ domain 396 471 2.0E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Pfam PF13180 PDZ domain 276 367 9.8E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 SUPERFAMILY SSF50156 233 357 3.02E-21 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 SUPERFAMILY SSF50494 45 260 1.76E-61 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 SUPERFAMILY SSF50156 385 471 1.97E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 46 471 1.1E-144 T 06-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Gene3D G3DSA:2.40.10.10 164 276 5.0E-41 T 06-07-2017 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 108 120 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 129 149 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 172 196 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 PRINTS PR00834 HtrA/DegQ protease family signature 316 328 2.7E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Gene3D G3DSA:2.40.10.10 45 155 6.1E-34 T 06-07-2017 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 SMART SM00228 276 358 8.7E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 SMART SM00228 384 466 2.1E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Pfam PF13365 Trypsin-like peptidase domain 99 236 6.0E-33 T 06-07-2017 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Gene3D G3DSA:2.30.42.10 277 373 2.7E-25 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS21425 2db04948e617ef64e32b62b0c4777f1d 475 Gene3D G3DSA:2.30.42.10 386 471 5.9E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS03665 6f302eef914e43bc9a3eddcef059327c 138 SMART SM00530 16 71 2.4E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS03665 6f302eef914e43bc9a3eddcef059327c 138 Gene3D G3DSA:1.10.260.40 13 76 1.0E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS03665 6f302eef914e43bc9a3eddcef059327c 138 SUPERFAMILY SSF47413 3 78 7.24E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS03665 6f302eef914e43bc9a3eddcef059327c 138 Pfam PF01381 Helix-turn-helix 17 70 4.6E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 SMART SM00382 164 307 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Gene3D G3DSA:3.40.50.300 141 316 4.0E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 SUPERFAMILY SSF52172 5 187 1.99E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 SMART SM00448 3 115 1.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 SUPERFAMILY SSF52540 143 386 7.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Pfam PF02954 Bacterial regulatory protein, Fis family 438 476 8.4E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Gene3D G3DSA:1.10.10.60 436 476 3.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Gene3D G3DSA:3.40.50.2300 4 128 5.4E-32 T 06-07-2017 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Gene3D G3DSA:1.10.8.60 319 387 2.5E-23 T 06-07-2017 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 SUPERFAMILY SSF46689 432 480 6.45E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Pfam PF00072 Response regulator receiver domain 5 114 7.0E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 Pfam PF00158 Sigma-54 interaction domain 144 310 9.9E-69 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAK95_RS28455 2de8fbc56b499169482fd4d59b2ea8a6 495 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAK95_RS21615 17c7474a8ced66a566585cadc3dbd1dd 111 Pfam PF05239 PRC-barrel domain 11 71 1.5E-8 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS21615 17c7474a8ced66a566585cadc3dbd1dd 111 SUPERFAMILY SSF50346 5 84 1.69E-14 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS21615 17c7474a8ced66a566585cadc3dbd1dd 111 Gene3D G3DSA:2.30.30.240 12 65 9.0E-11 T 06-07-2017 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Gene3D G3DSA:3.30.300.30 466 556 4.5E-9 T 06-07-2017 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 550 9.5E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 SUPERFAMILY SSF56801 26 562 5.23E-105 T 06-07-2017 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Pfam PF00501 AMP-binding enzyme 40 468 1.3E-67 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Gene3D G3DSA:2.30.38.10 403 462 1.2E-8 T 06-07-2017 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Gene3D G3DSA:3.40.50.980 203 349 6.5E-25 T 06-07-2017 CAK95_RS04730 a39aaca28a145fc131fef3c0fa1fe9e7 598 Gene3D G3DSA:3.40.50.980 33 202 1.2E-35 T 06-07-2017 CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 PIRSF PIRSF001434 1 389 8.6E-145 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 194 208 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 SUPERFAMILY SSF53383 11 387 5.71E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 385 8.0E-155 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 Gene3D G3DSA:3.40.640.10 8 251 3.9E-92 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS24910 24932ae4e36382c42ae43eeb5091b611 389 Gene3D G3DSA:3.90.1150.10 252 387 8.6E-56 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 SMART SM00347 42 142 7.7E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 Gene3D G3DSA:1.10.10.10 18 152 1.3E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 5.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 5.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 5.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 SUPERFAMILY SSF46785 18 152 6.13E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27770 91379668ef801ffa7b60823b07618faf 153 Pfam PF01047 MarR family 49 105 1.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS22840 6a25e3edee1dbeb61520f678b5f38585 149 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 31 115 1.7E-12 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS22840 6a25e3edee1dbeb61520f678b5f38585 149 Gene3D G3DSA:3.90.1590.10 5 141 2.0E-36 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS22840 6a25e3edee1dbeb61520f678b5f38585 149 SUPERFAMILY SSF51316 9 132 7.11E-39 T 06-07-2017 IPR011057 Mss4-like CAK95_RS07610 d35973888e17becb939aa9499872aba0 139 SUPERFAMILY SSF54637 4 137 4.69E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS07610 d35973888e17becb939aa9499872aba0 139 Pfam PF01575 MaoC like domain 8 105 4.3E-16 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS07610 d35973888e17becb939aa9499872aba0 139 Gene3D G3DSA:3.10.129.10 3 135 1.4E-30 T 06-07-2017 IPR029069 HotDog domain CAK95_RS26935 4639be3be08a27ceb1a633936255578f 149 Pfam PF13578 Methyltransferase domain 2 106 7.9E-9 T 06-07-2017 CAK95_RS26935 4639be3be08a27ceb1a633936255578f 149 Gene3D G3DSA:3.40.50.150 1 81 8.4E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26935 4639be3be08a27ceb1a633936255578f 149 SUPERFAMILY SSF53335 2 82 8.85E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS14980 85029236862b10765e80278530cc8440 520 Pfam PF00501 AMP-binding enzyme 16 419 9.0E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS14980 85029236862b10765e80278530cc8440 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS14980 85029236862b10765e80278530cc8440 520 Gene3D G3DSA:2.30.38.10 341 413 5.8E-18 T 06-07-2017 CAK95_RS14980 85029236862b10765e80278530cc8440 520 SUPERFAMILY SSF56801 8 512 2.49E-141 T 06-07-2017 CAK95_RS14980 85029236862b10765e80278530cc8440 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 502 5.6E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS14980 85029236862b10765e80278530cc8440 520 Gene3D G3DSA:3.40.50.980 9 172 2.0E-34 T 06-07-2017 CAK95_RS14980 85029236862b10765e80278530cc8440 520 Gene3D G3DSA:3.30.300.30 415 511 1.0E-26 T 06-07-2017 CAK95_RS14980 85029236862b10765e80278530cc8440 520 Gene3D G3DSA:3.40.50.980 173 328 5.3E-47 T 06-07-2017 CAK95_RS02015 98d889b4d00432aa66a1ac40fd9829fa 208 SUPERFAMILY SSF55811 13 138 9.07E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS02015 98d889b4d00432aa66a1ac40fd9829fa 208 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS02015 98d889b4d00432aa66a1ac40fd9829fa 208 Pfam PF00293 NUDIX domain 17 136 2.1E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS02015 98d889b4d00432aa66a1ac40fd9829fa 208 Gene3D G3DSA:3.90.79.10 5 137 4.4E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS27035 25d7f849ad87d6398921c35f82e3fc94 359 SUPERFAMILY SSF54768 11 139 1.13E-18 T 06-07-2017 CAK95_RS27035 25d7f849ad87d6398921c35f82e3fc94 359 Pfam PF06147 Protein of unknown function (DUF968) 246 308 2.6E-14 T 06-07-2017 IPR010373 Protein of unknown function DUF968 CAK95_RS27035 25d7f849ad87d6398921c35f82e3fc94 359 Pfam PF04098 Rad52/22 family double-strand break repair protein 9 145 1.0E-28 T 06-07-2017 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 6.0E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 SUPERFAMILY SSF46785 17 87 2.33E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 SMART SM00345 24 83 2.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 SUPERFAMILY SSF53383 85 452 1.25E-67 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 Pfam PF00155 Aminotransferase class I and II 98 394 3.8E-15 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 Gene3D G3DSA:1.10.10.10 16 84 1.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28910 18ca6c6c23b309137421aae8ebe07b4f 460 Gene3D G3DSA:3.40.640.10 128 346 1.5E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 PIRSF PIRSF001413 5 405 1.3E-157 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 Gene3D G3DSA:3.40.50.1100 109 187 3.4E-22 T 06-07-2017 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 400 1.6E-188 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 Gene3D G3DSA:3.40.50.1100 188 402 5.2E-90 T 06-07-2017 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 401 52.526 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 388 1.8E-44 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS10965 cd56bd9639246d48d040fc10d3ad70fa 405 SUPERFAMILY SSF53686 13 400 4.32E-146 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 262 279 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 399 409 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 282 308 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 409 432 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 364 388 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 324 342 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00463 E-class P450 group I signature 156 174 2.9E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 Pfam PF00067 Cytochrome P450 46 443 2.1E-77 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 SUPERFAMILY SSF48264 46 461 3.41E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 Gene3D G3DSA:1.10.630.10 46 464 1.4E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00385 P450 superfamily signature 273 290 6.9E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00385 P450 superfamily signature 325 336 6.9E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS26775 3464389747430800ab10cbbce0d0bbb8 483 PRINTS PR00385 P450 superfamily signature 400 409 6.9E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 Gene3D G3DSA:1.20.1050.10 94 201 4.6E-19 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 72 6.4E-17 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 129 191 8.2E-6 T 06-07-2017 CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 Gene3D G3DSA:3.40.30.10 1 93 4.7E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 SUPERFAMILY SSF47616 78 202 2.09E-22 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS19805 f497eeba32e85762343706c95e9fa89d 203 SUPERFAMILY SSF52833 1 88 1.84E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS03195 af8ef7d3045b7d04a75be5043a98ee39 279 Pfam PF09931 Uncharacterized conserved protein (DUF2163) 1 163 6.4E-59 T 06-07-2017 IPR019228 Bacteriophage phiJL001, Gp84, N-terminal CAK95_RS03195 af8ef7d3045b7d04a75be5043a98ee39 279 Pfam PF09356 Phage conserved hypothetical protein BR0599 192 270 6.7E-30 T 06-07-2017 IPR018964 Bacteriophage phiJL001, Gp84, C-terminal CAK95_RS03195 af8ef7d3045b7d04a75be5043a98ee39 279 TIGRFAM TIGR02218 phg_TIGR02218: phage conserved hypothetical protein BR0599 23 277 2.1E-78 T 06-07-2017 IPR011928 Bacteriophage phiJL001, Gp84 CAK95_RS17060 68846decd934abb083b18e2dc84a94d8 113 Pfam PF07883 Cupin domain 40 106 4.8E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS17060 68846decd934abb083b18e2dc84a94d8 113 Gene3D G3DSA:2.60.120.10 1 112 9.2E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS17060 68846decd934abb083b18e2dc84a94d8 113 SUPERFAMILY SSF51182 1 111 5.6E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS17790 e092d81bd3989557d6674f76215cd3f8 400 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 385 2.7E-80 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS17790 e092d81bd3989557d6674f76215cd3f8 400 SUPERFAMILY SSF111369 55 309 1.83E-62 T 06-07-2017 CAK95_RS17790 e092d81bd3989557d6674f76215cd3f8 400 Gene3D G3DSA:2.40.50.100 174 201 1.7E-20 T 06-07-2017 CAK95_RS17790 e092d81bd3989557d6674f76215cd3f8 400 Gene3D G3DSA:2.40.50.100 66 99 1.7E-20 T 06-07-2017 CAK95_RS17790 e092d81bd3989557d6674f76215cd3f8 400 Pfam PF13533 Biotin-lipoyl like 66 114 3.7E-15 T 06-07-2017 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 Pfam PF08281 Sigma-70, region 4 124 174 9.6E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 Pfam PF04542 Sigma-70 region 2 24 89 1.9E-4 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 Gene3D G3DSA:1.10.10.10 117 179 5.2E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 SUPERFAMILY SSF88659 102 179 2.62E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 Gene3D G3DSA:1.10.1740.10 16 90 3.4E-9 T 06-07-2017 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 SUPERFAMILY SSF88946 16 103 1.57E-8 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04845 7d711b916625c0ac48a61a8c5a900cd7 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 178 7.6E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS02345 f49971d87b9ba5527c17c7e98ffd7b61 811 SUPERFAMILY SSF52540 398 747 6.54E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02345 f49971d87b9ba5527c17c7e98ffd7b61 811 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 181 388 6.7E-13 T 06-07-2017 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 CAK95_RS02345 f49971d87b9ba5527c17c7e98ffd7b61 811 SMART SM00382 440 707 2.5E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02345 f49971d87b9ba5527c17c7e98ffd7b61 811 Gene3D G3DSA:3.40.50.300 629 704 1.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02345 f49971d87b9ba5527c17c7e98ffd7b61 811 Gene3D G3DSA:3.40.50.300 419 581 1.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19630 1f99964447b51339a7fa84d0862d28e4 399 Pfam PF03743 Bacterial conjugation TrbI-like protein 211 388 6.7E-62 T 06-07-2017 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 SUPERFAMILY SSF53850 36 535 4.52E-99 T 06-07-2017 CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 455 2.6E-80 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 Gene3D G3DSA:3.90.76.10 89 164 8.0E-17 T 06-07-2017 CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 Gene3D G3DSA:3.10.105.10 310 509 4.9E-41 T 06-07-2017 CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 Gene3D G3DSA:3.40.190.10 165 309 2.6E-33 T 06-07-2017 CAK95_RS16945 5a0d357f72b07efb401e3ef930a18d5b 539 PIRSF PIRSF002741 1 529 5.9E-71 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 SUPERFAMILY SSF141130 124 184 4.97E-85 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 SUPERFAMILY SSF141130 232 448 4.97E-85 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 SUPERFAMILY SSF141130 42 84 4.97E-85 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Pfam PF03069 Acetamidase/Formamidase family 128 269 6.5E-10 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Pfam PF03069 Acetamidase/Formamidase family 275 448 8.0E-20 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Gene3D G3DSA:2.60.120.580 37 84 6.8E-63 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Gene3D G3DSA:2.60.120.580 124 154 6.8E-63 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Gene3D G3DSA:2.60.120.580 255 341 6.8E-63 T 06-07-2017 CAK95_RS22475 0e2423162997af53d6b499befb6a9629 453 Gene3D G3DSA:3.10.28.20 351 449 3.5E-30 T 06-07-2017 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 Gene3D G3DSA:3.40.50.300 155 335 1.1E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 PIRSF PIRSF002401 1 345 2.9E-131 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 Hamap MF_01454 GTPase Obg [obg]. 2 327 45.9 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 SUPERFAMILY SSF82051 2 158 3.66E-54 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 Pfam PF01926 50S ribosome-binding GTPase 162 280 1.6E-23 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 326 1.4E-136 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 9.0E-33 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 9.0E-33 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 9.0E-33 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 9.0E-33 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 SUPERFAMILY SSF52540 152 337 8.86E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 Gene3D G3DSA:2.70.210.12 2 154 1.5E-57 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK95_RS07300 5c70759af1d54f89eb92b5e6fcae3187 346 Pfam PF01018 GTP1/OBG 3 158 5.3E-59 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK95_RS09620 7900aec5a1de3a2e5ed128db5b87f294 153 Gene3D G3DSA:3.10.129.10 4 150 3.3E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS09620 7900aec5a1de3a2e5ed128db5b87f294 153 SUPERFAMILY SSF54637 5 150 5.84E-38 T 06-07-2017 IPR029069 HotDog domain CAK95_RS09620 7900aec5a1de3a2e5ed128db5b87f294 153 Pfam PF01575 MaoC like domain 14 124 1.8E-15 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS01960 10229d1379799ff240639854226e860f 171 Pfam PF02674 Colicin V production protein 4 145 6.0E-23 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAK95_RS02680 9497e4202a2955abba5d00795b477ac9 582 Gene3D G3DSA:3.40.50.300 1 78 7.8E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02680 9497e4202a2955abba5d00795b477ac9 582 Pfam PF13175 AAA ATPase domain 1 46 1.8E-8 T 06-07-2017 CAK95_RS02680 9497e4202a2955abba5d00795b477ac9 582 Pfam PF13175 AAA ATPase domain 245 329 8.7E-17 T 06-07-2017 CAK95_RS02680 9497e4202a2955abba5d00795b477ac9 582 SUPERFAMILY SSF52540 1 342 4.63E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02680 9497e4202a2955abba5d00795b477ac9 582 Gene3D G3DSA:3.40.50.300 228 342 5.0E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17635 60a92a756ea9e82b9a227730399391e4 637 Pfam PF13727 CoA-binding domain 71 210 1.3E-5 T 06-07-2017 CAK95_RS17635 60a92a756ea9e82b9a227730399391e4 637 Pfam PF02719 Polysaccharide biosynthesis protein 296 589 1.8E-104 T 06-07-2017 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CAK95_RS17635 60a92a756ea9e82b9a227730399391e4 637 Gene3D G3DSA:3.40.50.720 295 483 1.9E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17635 60a92a756ea9e82b9a227730399391e4 637 SUPERFAMILY SSF51735 294 571 7.44E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17635 60a92a756ea9e82b9a227730399391e4 637 Gene3D G3DSA:3.90.25.10 484 569 1.2E-8 T 06-07-2017 CAK95_RS27490 4e4ab40dda4824c568bd23af6afc925b 259 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 225 4.8E-55 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS27490 4e4ab40dda4824c568bd23af6afc925b 259 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 226 1.9E-41 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS10190 607d712f3ec0ae4a073539bfcfbb1437 314 SUPERFAMILY SSF53850 24 255 2.12E-35 T 06-07-2017 CAK95_RS10190 607d712f3ec0ae4a073539bfcfbb1437 314 Pfam PF09084 NMT1/THI5 like 34 241 1.1E-20 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS10190 607d712f3ec0ae4a073539bfcfbb1437 314 Gene3D G3DSA:3.40.190.10 110 227 6.8E-19 T 06-07-2017 CAK95_RS10190 607d712f3ec0ae4a073539bfcfbb1437 314 SMART SM00062 25 251 0.0073 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS16985 41d176eaf1618f31c6dd7b2cac57293e 600 SUPERFAMILY SSF75304 4 442 2.49E-123 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16985 41d176eaf1618f31c6dd7b2cac57293e 600 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 37 594 2.8E-245 T 06-07-2017 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 CAK95_RS16985 41d176eaf1618f31c6dd7b2cac57293e 600 Pfam PF01425 Amidase 23 433 1.7E-93 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16985 41d176eaf1618f31c6dd7b2cac57293e 600 Gene3D G3DSA:3.90.1300.10 3 445 4.4E-121 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS07000 1b85e15590c4b481d244e6e5b3320f6a 337 SUPERFAMILY SSF81345 5 325 3.66E-67 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS07000 1b85e15590c4b481d244e6e5b3320f6a 337 Pfam PF01032 FecCD transport family 18 325 1.1E-75 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAK95_RS07000 1b85e15590c4b481d244e6e5b3320f6a 337 Gene3D G3DSA:1.10.3470.10 6 330 1.4E-85 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 Gene3D G3DSA:2.30.38.10 412 473 2.8E-13 T 06-07-2017 CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 234 245 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 Pfam PF00501 AMP-binding enzyme 68 473 4.5E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 Gene3D G3DSA:3.40.50.980 240 406 1.2E-21 T 06-07-2017 CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 SUPERFAMILY SSF56801 51 569 2.62E-78 T 06-07-2017 CAK95_RS24165 efd15350efb0c0b4c71f86718cb65195 632 Gene3D G3DSA:3.40.50.980 63 239 1.0E-20 T 06-07-2017 CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 257 2.0E-36 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 165 181 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 Gene3D G3DSA:3.40.47.10 12 268 1.4E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 SUPERFAMILY SSF53901 225 420 3.12E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 SUPERFAMILY SSF53901 12 264 7.44E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 SMART SM00825 Beta-ketoacyl synthase 12 424 3.4E-17 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 379 1.4E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK95_RS20160 a75b89383efba274ce6aad8616c7cf92 424 Gene3D G3DSA:3.40.47.10 275 420 5.6E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS01145 723b145c9295264fc6ded911520483a7 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 318 2.7E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01145 723b145c9295264fc6ded911520483a7 322 PIRSF PIRSF017082 1 321 1.8E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01145 723b145c9295264fc6ded911520483a7 322 SUPERFAMILY SSF53850 106 282 4.07E-14 T 06-07-2017 CAK95_RS17825 b954f11203d14ec6d1fbf012518f3855 224 Pfam PF04955 HupE / UreJ protein 39 215 6.6E-12 T 06-07-2017 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CAK95_RS17130 4ea819a6a288d00a2b1a071f663ba8b8 274 SUPERFAMILY SSF161098 71 257 6.02E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17130 4ea819a6a288d00a2b1a071f663ba8b8 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 254 7.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17130 4ea819a6a288d00a2b1a071f663ba8b8 274 Gene3D G3DSA:1.10.3720.10 76 263 9.2E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16150 e962bfe107222b362f42fc35fbcdab7c 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 3.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16150 e962bfe107222b362f42fc35fbcdab7c 257 Gene3D G3DSA:1.10.357.10 27 216 2.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS16150 e962bfe107222b362f42fc35fbcdab7c 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 1.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16150 e962bfe107222b362f42fc35fbcdab7c 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 1.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16150 e962bfe107222b362f42fc35fbcdab7c 257 SUPERFAMILY SSF46689 29 97 5.49E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS23475 82d4c59c0ba7788b8cb1f2b85d7fd443 257 Gene3D G3DSA:1.10.760.10 84 182 1.7E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23475 82d4c59c0ba7788b8cb1f2b85d7fd443 257 SUPERFAMILY SSF46626 88 182 7.9E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23475 82d4c59c0ba7788b8cb1f2b85d7fd443 257 SUPERFAMILY SSF46626 29 37 7.9E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23475 82d4c59c0ba7788b8cb1f2b85d7fd443 257 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 95 178 1.4E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 3.4E-152 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 SUPERFAMILY SSF52540 3 303 4.01E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Gene3D G3DSA:3.10.20.30 269 364 9.3E-48 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 365 44.086 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 SUPERFAMILY SSF81271 281 362 3.05E-36 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Pfam PF01926 50S ribosome-binding GTPase 5 129 2.2E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Pfam PF06071 Protein of unknown function (DUF933) 281 363 2.7E-39 T 06-07-2017 IPR013029 Domain of unknown function DUF933 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Gene3D G3DSA:1.10.150.300 132 201 1.2E-24 T 06-07-2017 IPR023192 TGS-like domain CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 PIRSF PIRSF006641 1 365 8.7E-155 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Gene3D G3DSA:3.40.50.300 202 268 2.8E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 Gene3D G3DSA:3.40.50.300 4 131 2.8E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.1E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 4.1E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 4.1E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS13485 fb707d09fe9c39f93d77a00883cbd431 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 4.1E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23995 b82d96e0023566398260c2234b290452 333 SUPERFAMILY SSF53850 125 296 9.64E-11 T 06-07-2017 CAK95_RS23995 b82d96e0023566398260c2234b290452 333 PIRSF PIRSF017082 2 333 3.5E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS23995 b82d96e0023566398260c2234b290452 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 329 6.0E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27245 489b7d91ae93f2dc08ed29e77c77ab4e 306 SUPERFAMILY SSF53474 20 301 2.07E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27245 489b7d91ae93f2dc08ed29e77c77ab4e 306 Gene3D G3DSA:3.40.50.1820 19 302 4.6E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27245 489b7d91ae93f2dc08ed29e77c77ab4e 306 Pfam PF12697 Alpha/beta hydrolase family 39 294 9.8E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20455 a05905a4c121c787b8fe9b314d203194 152 PIRSF PIRSF024492 2 152 7.9E-36 T 06-07-2017 IPR014519 Uncharacterised conserved protein UCP024492 CAK95_RS20455 a05905a4c121c787b8fe9b314d203194 152 Pfam PF04343 Protein of unknown function, DUF488 17 135 3.7E-29 T 06-07-2017 IPR007438 Protein of unknown function DUF488 CAK95_RS24815 58dc809ffce76bd29a023a7c301aef72 174 Gene3D G3DSA:3.40.250.10 3 102 8.2E-18 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24815 58dc809ffce76bd29a023a7c301aef72 174 SUPERFAMILY SSF52821 3 151 4.06E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24815 58dc809ffce76bd29a023a7c301aef72 174 Pfam PF00581 Rhodanese-like domain 6 97 1.0E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24815 58dc809ffce76bd29a023a7c301aef72 174 SMART SM00450 4 100 2.3E-11 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24815 58dc809ffce76bd29a023a7c301aef72 174 Pfam PF11127 Protein of unknown function (DUF2892) 113 170 2.4E-10 T 06-07-2017 IPR021309 Protein of unknown function DUF2892 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 Gene3D G3DSA:3.10.450.50 171 286 1.3E-8 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 Gene3D G3DSA:1.10.10.10 108 162 8.5E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 SUPERFAMILY SSF88659 105 161 5.61E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 162 9.9E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 Gene3D G3DSA:1.10.1740.10 8 74 2.1E-16 T 06-07-2017 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 SUPERFAMILY SSF54427 172 286 7.47E-11 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 Pfam PF04542 Sigma-70 region 2 10 74 2.5E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 Pfam PF08281 Sigma-70, region 4 109 160 4.7E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS25990 60256218934e5d208cae0a053a372f0d 294 SUPERFAMILY SSF88946 8 70 8.24E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS14670 9d7d2aac238b8806439244d7d8fcf9f3 279 Pfam PF00593 TonB dependent receptor 44 277 3.2E-18 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS14670 9d7d2aac238b8806439244d7d8fcf9f3 279 SUPERFAMILY SSF56935 9 279 2.29E-38 T 06-07-2017 CAK95_RS14670 9d7d2aac238b8806439244d7d8fcf9f3 279 Gene3D G3DSA:2.40.170.20 9 279 2.6E-52 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS10810 78d907d66ed845f063a20c0c9c679ceb 431 Pfam PF08421 Putative zinc binding domain 26 87 4.6E-23 T 06-07-2017 IPR013630 Methyltransferase putative zinc binding domain CAK95_RS10810 78d907d66ed845f063a20c0c9c679ceb 431 Gene3D G3DSA:3.40.50.150 112 277 2.8E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10810 78d907d66ed845f063a20c0c9c679ceb 431 Pfam PF13489 Methyltransferase domain 118 259 3.8E-13 T 06-07-2017 CAK95_RS10810 78d907d66ed845f063a20c0c9c679ceb 431 Pfam PF08484 C-methyltransferase C-terminal domain 266 425 1.7E-65 T 06-07-2017 IPR013691 C-methyltransferase CAK95_RS10810 78d907d66ed845f063a20c0c9c679ceb 431 SUPERFAMILY SSF53335 84 271 1.14E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 PIRSF PIRSF015592 27 232 9.5E-41 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 Pfam PF01470 Pyroglutamyl peptidase 29 216 2.2E-26 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 SUPERFAMILY SSF53182 28 226 1.96E-47 T 06-07-2017 CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 Gene3D G3DSA:3.40.630.20 27 227 1.8E-47 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 30 53 1.2E-14 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 90 102 1.2E-14 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 189 201 1.2E-14 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CAK95_RS18700 4679b05af9d51e16f5dfa3f0eaf9c6dc 232 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 159 175 1.2E-14 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CAK95_RS01020 56da4bc5e97f2845b0054f5fd63a374c 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 284 6.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 SUPERFAMILY SSF46626 36 107 2.88E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 Pfam PF00034 Cytochrome c 37 103 2.5E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 Gene3D G3DSA:1.10.760.10 129 207 3.4E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 Gene3D G3DSA:1.10.760.10 35 105 7.2E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 SUPERFAMILY SSF46626 135 207 1.17E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03785 d1fe28cd95c9d21e4cb9e1ab71971985 216 PIRSF PIRSF000005 2 210 1.2E-47 T 06-07-2017 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 CAK95_RS09775 9c2899d499c3e6717717c646616ced47 488 Gene3D G3DSA:3.40.50.2000 3 238 5.7E-71 T 06-07-2017 CAK95_RS09775 9c2899d499c3e6717717c646616ced47 488 Gene3D G3DSA:3.40.50.2000 243 435 5.5E-71 T 06-07-2017 CAK95_RS09775 9c2899d499c3e6717717c646616ced47 488 Pfam PF00982 Glycosyltransferase family 20 19 451 7.6E-132 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CAK95_RS09775 9c2899d499c3e6717717c646616ced47 488 SUPERFAMILY SSF53756 3 452 1.51E-138 T 06-07-2017 CAK95_RS05165 54e8e56728f060458d08eec5eb01b36b 241 Pfam PF00510 Cytochrome c oxidase subunit III 51 215 9.2E-10 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05165 54e8e56728f060458d08eec5eb01b36b 241 SUPERFAMILY SSF81452 5 218 4.29E-40 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05165 54e8e56728f060458d08eec5eb01b36b 241 Gene3D G3DSA:1.20.120.80 47 218 2.9E-35 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS24010 a023610d5c85a82d924eb2cfa8ae9fd0 224 Pfam PF03734 L,D-transpeptidase catalytic domain 79 215 7.5E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS24010 a023610d5c85a82d924eb2cfa8ae9fd0 224 SUPERFAMILY SSF141523 73 126 3.53E-31 T 06-07-2017 CAK95_RS24010 a023610d5c85a82d924eb2cfa8ae9fd0 224 SUPERFAMILY SSF141523 154 216 3.53E-31 T 06-07-2017 CAK95_RS24010 a023610d5c85a82d924eb2cfa8ae9fd0 224 Gene3D G3DSA:2.40.440.10 72 216 1.4E-31 T 06-07-2017 CAK95_RS10055 43ead8ff4fa2bd80e777113829c96736 309 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 54 295 5.1E-50 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS23460 de57b5ae85ce845e1bd6fdedd985a196 111 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 15 103 1.6E-32 T 06-07-2017 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ CAK95_RS23460 de57b5ae85ce845e1bd6fdedd985a196 111 Pfam PF08770 Sulphur oxidation protein SoxZ 16 101 5.6E-31 T 06-07-2017 IPR014880 Sulphur oxidation protein SoxZ CAK95_RS23460 de57b5ae85ce845e1bd6fdedd985a196 111 SUPERFAMILY SSF81296 10 109 2.8E-30 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK95_RS23460 de57b5ae85ce845e1bd6fdedd985a196 111 Gene3D G3DSA:2.60.40.10 14 109 3.7E-33 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 PIRSF PIRSF000331 1 485 2.2E-117 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 Gene3D G3DSA:1.20.140.10 259 474 7.3E-33 T 06-07-2017 CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 SUPERFAMILY SSF56645 1 266 7.07E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 275 473 1.4E-42 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 266 7.3E-77 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 SUPERFAMILY SSF47203 257 475 5.02E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 Gene3D G3DSA:2.40.110.10 139 258 3.0E-34 T 06-07-2017 CAK95_RS27320 9d58b1f18a07f86931eee62d1fdaed34 488 Gene3D G3DSA:1.10.3140.10 2 137 6.0E-39 T 06-07-2017 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Gene3D G3DSA:3.30.1360.40 242 338 1.5E-25 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 13 745 2.3E-259 T 06-07-2017 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Gene3D G3DSA:2.120.10.90 507 734 2.5E-35 T 06-07-2017 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 SUPERFAMILY SSF101904 509 744 1.09E-52 T 06-07-2017 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 SUPERFAMILY SSF56719 36 484 4.45E-155 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 654 690 7.5E-5 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 559 601 1.2 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 609 651 0.42 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 37 468 2.6E-138 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Gene3D G3DSA:3.90.199.10 36 241 3.1E-106 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Gene3D G3DSA:3.90.199.10 340 404 3.1E-106 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 SMART SM00434 16 468 1.5E-223 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22375 a28229a881bad2e777e77da12dc63403 750 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 9 746 32.408 T 06-07-2017 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS20855 8c115d867958625afd7b8b10849dd0b0 293 Gene3D G3DSA:3.20.20.60 1 240 1.0E-66 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS20855 8c115d867958625afd7b8b10849dd0b0 293 PIRSF PIRSF015582 1 293 1.9E-77 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK95_RS20855 8c115d867958625afd7b8b10849dd0b0 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 2 229 5.3E-37 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS20855 8c115d867958625afd7b8b10849dd0b0 293 SUPERFAMILY SSF51621 1 240 3.45E-56 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 12 190 8.1E-68 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 Pfam PF00625 Guanylate kinase 14 191 9.7E-43 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 ProSitePatterns PS00856 Guanylate kinase-like signature. 45 62 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 Gene3D G3DSA:3.30.63.10 41 92 4.7E-24 T 06-07-2017 CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 SUPERFAMILY SSF52540 9 197 1.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 Gene3D G3DSA:3.40.50.300 9 33 6.1E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 Gene3D G3DSA:3.40.50.300 93 202 6.1E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 Hamap MF_00328 Guanylate kinase [gmk]. 9 193 35.296 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAK95_RS25870 29cfe74c1c43176b9e77c61c134894dc 218 SMART SM00072 10 193 5.6E-50 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK95_RS10625 a1826ab33eac4c61755549bd88e2e2f4 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 1.6E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10625 a1826ab33eac4c61755549bd88e2e2f4 329 SUPERFAMILY SSF53850 118 291 3.75E-13 T 06-07-2017 CAK95_RS10625 a1826ab33eac4c61755549bd88e2e2f4 329 PIRSF PIRSF017082 3 329 1.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS09790 b6271097b1bdf1f5f0e2565c366684b4 458 SUPERFAMILY SSF51604 189 338 4.71E-11 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS09790 b6271097b1bdf1f5f0e2565c366684b4 458 Gene3D G3DSA:3.20.20.120 189 294 6.4E-10 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 SUPERFAMILY SSF51395 483 1249 6.11E-265 T 06-07-2017 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Gene3D G3DSA:3.60.20.10 45 478 2.4E-191 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Pfam PF01645 Conserved region in glutamate synthase 845 1215 2.0E-153 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 SUPERFAMILY SSF69336 1264 1480 9.81E-92 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 SUPERFAMILY SSF69336 1509 1557 9.81E-92 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Gene3D G3DSA:3.20.20.70 483 832 2.0E-112 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Gene3D G3DSA:3.20.20.70 884 1254 6.2E-182 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 SUPERFAMILY SSF56235 45 469 1.64E-161 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Pfam PF04898 Glutamate synthase central domain 495 780 1.7E-115 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Pfam PF01493 GXGXG motif 1295 1481 2.2E-81 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Gene3D G3DSA:2.160.20.60 1269 1566 2.3E-107 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS16440 46f711a44eb6c03dfb9a0d52f5f3f4a0 1572 Pfam PF00310 Glutamine amidotransferases class-II 45 467 2.6E-187 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAK95_RS18010 c9cc8fa399ecdc221b2988dee7740031 275 Pfam PF00149 Calcineurin-like phosphoesterase 20 219 1.2E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS18010 c9cc8fa399ecdc221b2988dee7740031 275 Gene3D G3DSA:3.60.21.10 200 253 2.2E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS18010 c9cc8fa399ecdc221b2988dee7740031 275 Gene3D G3DSA:3.60.21.10 20 138 2.2E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS18010 c9cc8fa399ecdc221b2988dee7740031 275 SUPERFAMILY SSF56300 19 140 1.44E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS18010 c9cc8fa399ecdc221b2988dee7740031 275 SUPERFAMILY SSF56300 196 254 1.44E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS17815 9185c09d79accc546413953d97a04dea 307 SUPERFAMILY SSF103481 195 294 9.94E-14 T 06-07-2017 CAK95_RS17815 9185c09d79accc546413953d97a04dea 307 SUPERFAMILY SSF103481 43 141 3.79E-15 T 06-07-2017 CAK95_RS17815 9185c09d79accc546413953d97a04dea 307 Pfam PF00892 EamA-like transporter family 161 290 1.9E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS17815 9185c09d79accc546413953d97a04dea 307 Pfam PF00892 EamA-like transporter family 5 138 3.8E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS23770 bc1472d000202e7faf451bde53bbd5eb 89 SUPERFAMILY SSF81901 15 59 6.93E-6 T 06-07-2017 CAK95_RS23770 bc1472d000202e7faf451bde53bbd5eb 89 Gene3D G3DSA:1.25.40.10 14 72 3.9E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS23770 bc1472d000202e7faf451bde53bbd5eb 89 SMART SM00671 21 56 9.7E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 SUPERFAMILY SSF48498 118 244 2.22E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 ProSitePatterns PS01081 TetR-type HTH domain signature. 59 89 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 SUPERFAMILY SSF46689 41 112 1.54E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 Gene3D G3DSA:1.10.357.10 32 240 3.3E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12405 2a1c66b215f18ca48f7c550563222a9f 269 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 93 9.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 Gene3D G3DSA:1.20.1250.20 45 213 4.2E-36 T 06-07-2017 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 SUPERFAMILY SSF103473 28 224 4.45E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 Pfam PF07690 Major Facilitator Superfamily 49 441 3.1E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 158 7.2E-7 T 06-07-2017 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 7.2E-7 T 06-07-2017 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 48 72 7.2E-7 T 06-07-2017 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 Gene3D G3DSA:1.20.1250.20 293 509 1.4E-18 T 06-07-2017 CAK95_RS18920 8288667279828e9de15b6f09e0cf245b 519 SUPERFAMILY SSF103473 217 503 1.15E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS24225 790937f412e2aebb50e1167ffac9e7bc 275 Gene3D G3DSA:1.20.144.10 82 223 7.7E-17 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS24225 790937f412e2aebb50e1167ffac9e7bc 275 Pfam PF01569 PAP2 superfamily 95 218 5.1E-17 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS24225 790937f412e2aebb50e1167ffac9e7bc 275 SUPERFAMILY SSF48317 11 223 4.25E-21 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 Pfam PF01494 FAD binding domain 15 161 1.6E-9 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 SUPERFAMILY SSF54373 171 301 1.77E-31 T 06-07-2017 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 356 372 2.6E-15 T 06-07-2017 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 2.6E-15 T 06-07-2017 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 2.6E-15 T 06-07-2017 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 2.6E-15 T 06-07-2017 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 Gene3D G3DSA:3.50.50.60 296 374 2.9E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 Gene3D G3DSA:3.50.50.60 12 172 2.9E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 SUPERFAMILY SSF51905 295 381 1.2E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16160 57380a104344a18fa24c915a962361ac 411 SUPERFAMILY SSF51905 13 167 1.2E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS25845 7d5bcaef40baaa065a161bb5d6dca889 826 Gene3D G3DSA:2.40.160.10 602 774 6.6E-4 T 06-07-2017 IPR023614 Porin domain CAK95_RS25845 7d5bcaef40baaa065a161bb5d6dca889 826 Pfam PF04453 Organic solvent tolerance protein 328 750 4.2E-79 T 06-07-2017 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 CAK95_RS25845 7d5bcaef40baaa065a161bb5d6dca889 826 SUPERFAMILY SSF56935 603 773 1.5E-5 T 06-07-2017 CAK95_RS25845 7d5bcaef40baaa065a161bb5d6dca889 826 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 25 812 18.907 T 06-07-2017 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 CAK95_RS25845 7d5bcaef40baaa065a161bb5d6dca889 826 Gene3D G3DSA:2.60.450.10 61 222 2.2E-18 T 06-07-2017 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 SMART SM00562 3 140 2.9E-77 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 SUPERFAMILY SSF54919 1 139 8.12E-54 T 06-07-2017 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 Pfam PF00334 Nucleoside diphosphate kinase 4 138 1.9E-51 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 33.786 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.1E-32 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.1E-32 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.1E-32 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.1E-32 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.1E-32 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK95_RS25775 fdec7ae8e2088156cb360124636ad463 140 Gene3D G3DSA:3.30.70.141 1 139 4.8E-53 T 06-07-2017 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 PRINTS PR00834 HtrA/DegQ protease family signature 180 197 9.9E-6 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 PRINTS PR00834 HtrA/DegQ protease family signature 256 268 9.9E-6 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 PRINTS PR00834 HtrA/DegQ protease family signature 84 104 9.9E-6 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 9.9E-6 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 Gene3D G3DSA:2.40.10.10 50 125 8.0E-11 T 06-07-2017 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 Gene3D G3DSA:2.40.10.10 126 229 1.2E-6 T 06-07-2017 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 Pfam PF13180 PDZ domain 228 307 1.4E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 Pfam PF13365 Trypsin-like peptidase domain 54 187 1.3E-10 T 06-07-2017 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 SUPERFAMILY SSF50156 204 311 2.76E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 SUPERFAMILY SSF50494 20 221 4.83E-27 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 Gene3D G3DSA:2.30.42.10 230 309 5.4E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS06525 1a1a08e6bed1219425489991faa9d1fb 321 SMART SM00228 228 299 7.1E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 Pfam PF01467 Cytidylyltransferase-like 359 452 3.8E-14 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 Hamap MF_01603 Bifunctional protein HldE [hldE]. 7 488 40.779 T 06-07-2017 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 Gene3D G3DSA:3.40.1190.20 16 322 1.7E-65 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 Pfam PF00294 pfkB family carbohydrate kinase 16 313 3.0E-47 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 SUPERFAMILY SSF53613 15 322 4.37E-57 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 54 77 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 347 485 9.1E-60 T 06-07-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 356 419 5.5E-15 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 9 322 2.3E-118 T 06-07-2017 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 Gene3D G3DSA:3.40.50.620 355 472 1.4E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS17605 2fac1395974100029e179d8a75693cde 491 SUPERFAMILY SSF52374 355 483 2.51E-23 T 06-07-2017 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Gene3D G3DSA:2.160.10.10 126 227 9.6E-27 T 06-07-2017 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 285 313 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 17 342 2.1E-107 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 SUPERFAMILY SSF51161 44 333 1.8E-75 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 240 275 8.6E-9 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 147 179 4.6E-9 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 14 343 34.351 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 33 100 2.8E-17 T 06-07-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK95_RS23000 58b33e12e1ca48552bcc1c1809992072 355 Gene3D G3DSA:2.160.10.10 228 339 3.7E-28 T 06-07-2017 CAK95_RS23585 2982cd693812d6e6c8e6b92ef7bf3e14 119 Pfam PF01152 Bacterial-like globin 4 110 2.2E-16 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 CAK95_RS23585 2982cd693812d6e6c8e6b92ef7bf3e14 119 Gene3D G3DSA:1.10.490.10 3 117 3.8E-28 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK95_RS23585 2982cd693812d6e6c8e6b92ef7bf3e14 119 SUPERFAMILY SSF46458 4 117 9.26E-26 T 06-07-2017 IPR009050 Globin-like CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 Pfam PF01636 Phosphotransferase enzyme family 182 439 1.4E-23 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 Gene3D G3DSA:3.90.1200.10 277 509 3.3E-63 T 06-07-2017 CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 PIRSF PIRSF036599 7 513 4.1E-201 T 06-07-2017 IPR012180 Predicted bifunctional ATPase/phosphotransferase CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 Gene3D G3DSA:3.40.50.300 12 161 3.0E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 18 137 1.2E-28 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 SUPERFAMILY SSF56112 166 503 1.87E-47 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 SUPERFAMILY SSF52540 33 129 4.01E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 18 137 3.5E-32 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAK95_RS11025 c8077c55f13e51aab55feed976395bec 514 Gene3D G3DSA:3.30.200.20 162 267 3.0E-28 T 06-07-2017 CAK95_RS05975 f71ea76860862bb74254e443a13b4e39 382 SUPERFAMILY SSF56796 5 376 4.58E-107 T 06-07-2017 CAK95_RS05975 f71ea76860862bb74254e443a13b4e39 382 Gene3D G3DSA:3.40.50.1970 4 184 7.5E-50 T 06-07-2017 CAK95_RS05975 f71ea76860862bb74254e443a13b4e39 382 Gene3D G3DSA:1.20.1090.10 185 376 6.8E-49 T 06-07-2017 CAK95_RS05975 f71ea76860862bb74254e443a13b4e39 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 367 2.7E-101 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAK95_RS05975 f71ea76860862bb74254e443a13b4e39 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 Pfam PF08281 Sigma-70, region 4 120 172 9.2E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 Gene3D G3DSA:1.10.1740.10 2 115 2.1E-30 T 06-07-2017 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 Pfam PF04542 Sigma-70 region 2 24 90 1.2E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 175 8.5E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 SUPERFAMILY SSF88659 109 177 5.79E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 Gene3D G3DSA:1.10.10.10 116 177 1.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18620 79a8ebd58c290d30d4d81a22ac3fb644 186 SUPERFAMILY SSF88946 2 104 1.73E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS08700 508107ba87021c1eecaa740237eb0fe2 325 PIRSF PIRSF017082 1 324 4.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08700 508107ba87021c1eecaa740237eb0fe2 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 2.5E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08700 508107ba87021c1eecaa740237eb0fe2 325 SUPERFAMILY SSF53850 109 284 3.8E-14 T 06-07-2017 CAK95_RS27350 751d35d3b36942f1b5d1f1cd25d6f590 266 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27350 751d35d3b36942f1b5d1f1cd25d6f590 266 SUPERFAMILY SSF52540 4 222 1.43E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27350 751d35d3b36942f1b5d1f1cd25d6f590 266 Gene3D G3DSA:3.40.50.300 3 219 2.9E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27350 751d35d3b36942f1b5d1f1cd25d6f590 266 Pfam PF00005 ABC transporter 25 163 3.7E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27350 751d35d3b36942f1b5d1f1cd25d6f590 266 SMART SM00382 33 214 3.9E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25740 b6b56e9f4dfb47d8150de2b1b325d11a 181 PIRSF PIRSF000847 1 180 5.6E-41 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK95_RS25740 b6b56e9f4dfb47d8150de2b1b325d11a 181 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 66 3.2E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 SUPERFAMILY SSF53850 96 289 1.16E-18 T 06-07-2017 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 8.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 Gene3D G3DSA:3.40.190.10 193 245 3.9E-4 T 06-07-2017 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 Pfam PF03466 LysR substrate binding domain 94 283 1.2E-15 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 Gene3D G3DSA:3.40.190.10 94 192 4.6E-10 T 06-07-2017 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 Gene3D G3DSA:1.10.10.10 8 88 5.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10515 e08588bab539fac4ad3feb8d72e7ffc4 302 SUPERFAMILY SSF46785 5 116 2.72E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 Gene3D G3DSA:1.20.1050.10 135 216 1.6E-9 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 Pfam PF13410 Glutathione S-transferase, C-terminal domain 148 214 3.4E-8 T 06-07-2017 CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 SUPERFAMILY SSF52833 16 107 8.89E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 Gene3D G3DSA:3.40.30.10 4 107 1.5E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 Pfam PF13417 Glutathione S-transferase, N-terminal domain 15 82 5.7E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS08120 1939e3ed4f5664889477955ee12a8951 237 SUPERFAMILY SSF47616 133 217 5.46E-12 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS00940 da342bcc469b1e06005a84a77f8bab9b 455 SUPERFAMILY SSF50022 20 142 1.18E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00940 da342bcc469b1e06005a84a77f8bab9b 455 Pfam PF00355 Rieske [2Fe-2S] domain 27 109 6.6E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00940 da342bcc469b1e06005a84a77f8bab9b 455 Gene3D G3DSA:2.102.10.10 26 141 4.1E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00940 da342bcc469b1e06005a84a77f8bab9b 455 SUPERFAMILY SSF55961 139 389 3.85E-49 T 06-07-2017 CAK95_RS18185 bb764d7732b4c531fcbd4d9c461fa07e 602 Pfam PF00999 Sodium/hydrogen exchanger family 19 378 1.6E-69 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK95_RS18185 bb764d7732b4c531fcbd4d9c461fa07e 602 Pfam PF02254 TrkA-N domain 406 517 9.2E-18 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK95_RS18185 bb764d7732b4c531fcbd4d9c461fa07e 602 Gene3D G3DSA:3.40.50.720 400 531 6.5E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS18185 bb764d7732b4c531fcbd4d9c461fa07e 602 SUPERFAMILY SSF51735 405 530 3.29E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS18185 bb764d7732b4c531fcbd4d9c461fa07e 602 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 19 289 2.5E-81 T 06-07-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CAK95_RS05505 f057cc73b61a75eeae967662883467bf 248 Pfam PF02104 SURF1 family 24 229 8.0E-36 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 SUPERFAMILY SSF101904 809 913 4.05E-97 T 06-07-2017 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 SUPERFAMILY SSF101904 545 756 4.05E-97 T 06-07-2017 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Gene3D G3DSA:3.30.1360.40 257 353 7.3E-39 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 SUPERFAMILY SSF56719 51 534 2.35E-181 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 SMART SM00434 32 511 4.7E-285 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Gene3D G3DSA:3.90.199.10 55 237 1.6E-82 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 53 518 3.7E-153 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 17 910 23.898 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 29 908 0.0 T 06-07-2017 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 812 858 7.4E-12 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 605 649 6.4E-4 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 703 1.2E-6 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 754 1.2E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 596 3.5E-14 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 862 908 1.4E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Gene3D G3DSA:2.120.10.90 542 755 1.9E-117 T 06-07-2017 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Gene3D G3DSA:2.120.10.90 809 908 1.9E-117 T 06-07-2017 CAK95_RS22245 bd0ac1f54a806d989a9ce10bd037ddf3 919 Gene3D G3DSA:1.10.268.10 384 508 2.0E-41 T 06-07-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK95_RS04460 69e9a66f2931b185a3a88ec4f069e121 234 Gene3D G3DSA:3.40.50.300 1 226 2.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04460 69e9a66f2931b185a3a88ec4f069e121 234 SUPERFAMILY SSF52540 1 225 1.22E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04460 69e9a66f2931b185a3a88ec4f069e121 234 Pfam PF00005 ABC transporter 18 161 1.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04460 69e9a66f2931b185a3a88ec4f069e121 234 SMART SM00382 26 210 2.3E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 SUPERFAMILY SSF52374 2 319 6.4E-93 T 06-07-2017 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 Gene3D G3DSA:1.20.120.640 315 367 1.9E-4 T 06-07-2017 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 Gene3D G3DSA:3.40.50.620 20 311 1.0E-101 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 447 36.628 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 445 2.7E-140 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 SUPERFAMILY SSF47323 316 445 1.7E-29 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.0E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 2.0E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 64 73 2.0E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 2.0E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK95_RS20045 fa45e6aeffb9a0481e23b7871e7982d6 448 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 319 1.8E-114 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAK95_RS06815 63eb2c20058676a9ac087ff4b3db4df8 462 Pfam PF07813 LTXXQ motif family protein 365 454 2.4E-17 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS06815 63eb2c20058676a9ac087ff4b3db4df8 462 Pfam PF07813 LTXXQ motif family protein 241 331 3.5E-15 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 SUPERFAMILY SSF52129 14 252 7.63E-55 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 Gene3D G3DSA:3.40.50.1460 24 252 9.6E-21 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 SMART SM00115 21 251 0.0022 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 PRINTS PR00376 Interleukin-1B converting enzyme signature 25 38 1.8E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 PRINTS PR00376 Interleukin-1B converting enzyme signature 61 79 1.8E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 PRINTS PR00376 Interleukin-1B converting enzyme signature 241 250 1.8E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 PRINTS PR00376 Interleukin-1B converting enzyme signature 139 157 1.8E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS05765 3ad557219a01a60001e9cbf9d13692a6 519 Pfam PF00656 Caspase domain 27 249 7.7E-35 T 06-07-2017 CAK95_RS07225 8a18890cfffd44fb3857f3c653ca9de6 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07225 8a18890cfffd44fb3857f3c653ca9de6 192 Gene3D G3DSA:1.10.357.10 9 164 1.3E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS07225 8a18890cfffd44fb3857f3c653ca9de6 192 SUPERFAMILY SSF46689 13 69 3.19E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07225 8a18890cfffd44fb3857f3c653ca9de6 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07225 8a18890cfffd44fb3857f3c653ca9de6 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS12925 d1d0de2b09c544172d650f7a53a4cb82 477 Gene3D G3DSA:3.30.360.30 171 477 5.3E-152 T 06-07-2017 IPR023181 Homospermidine synthase-like, domain KEGG: 00960+2.5.1.44 CAK95_RS12925 d1d0de2b09c544172d650f7a53a4cb82 477 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 14 157 2.3E-34 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CAK95_RS12925 d1d0de2b09c544172d650f7a53a4cb82 477 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 161 440 3.1E-26 T 06-07-2017 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CAK95_RS12925 d1d0de2b09c544172d650f7a53a4cb82 477 Gene3D G3DSA:3.40.50.720 2 170 1.9E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 SUPERFAMILY SSF140490 423 509 2.75E-28 T 06-07-2017 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 SMART SM00928 426 471 5.0E-19 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 SUPERFAMILY SSF142019 97 337 1.03E-86 T 06-07-2017 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 SUPERFAMILY SSF52833 3 86 1.25E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 264 279 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 439 450 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 428 510 8.5E-31 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 146 316 8.6E-46 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 SUPERFAMILY SSF142984 341 421 2.22E-20 T 06-07-2017 CAK95_RS12295 d68b9c9c1878f0db1c1a21d181b8f184 519 Gene3D G3DSA:3.40.30.10 9 83 4.5E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS21850 8073210cdf88dc81d2388c9621dc0a40 243 SUPERFAMILY SSF56281 1 243 1.35E-54 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS21850 8073210cdf88dc81d2388c9621dc0a40 243 Pfam PF12706 Beta-lactamase superfamily domain 30 219 1.8E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS21850 8073210cdf88dc81d2388c9621dc0a40 243 SMART SM00849 18 218 3.4E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS21850 8073210cdf88dc81d2388c9621dc0a40 243 Gene3D G3DSA:3.60.15.10 1 243 1.5E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 96 112 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 SUPERFAMILY SSF103473 30 429 1.01E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 Gene3D G3DSA:1.20.1250.20 42 227 1.7E-30 T 06-07-2017 CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 Gene3D G3DSA:1.20.1250.20 240 430 2.6E-10 T 06-07-2017 CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 42 427 8.9E-79 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAK95_RS01720 5deeafc25a51768a885b3040643daeab 434 Pfam PF07690 Major Facilitator Superfamily 47 393 3.0E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS27510 68ff58c3abcd72131ba3f40176c0385e 418 Gene3D G3DSA:2.40.160.10 244 395 9.7E-4 T 06-07-2017 IPR023614 Porin domain CAK95_RS27510 68ff58c3abcd72131ba3f40176c0385e 418 Pfam PF10082 Putative beta-barrel porin 2 34 418 1.5E-88 T 06-07-2017 IPR018759 Putative beta-barrel porin 2 CAK95_RS12335 816987603361cb4eab399a1cde775a82 452 Pfam PF01425 Amidase 24 437 2.6E-81 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS12335 816987603361cb4eab399a1cde775a82 452 Gene3D G3DSA:3.90.1300.10 6 447 1.5E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS12335 816987603361cb4eab399a1cde775a82 452 SUPERFAMILY SSF75304 6 447 1.44E-109 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 SMART SM00922 144 241 7.0E-20 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 191 222 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 Pfam PF13378 Enolase C-terminal domain-like 148 361 1.4E-48 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 125 2.2E-28 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 Gene3D G3DSA:3.30.390.10 2 128 6.3E-40 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 3 369 5.8E-134 T 06-07-2017 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 Gene3D G3DSA:3.20.20.120 129 359 1.1E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 SUPERFAMILY SSF51604 131 368 3.8E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS05795 1841c0dcbae743fe39f1652eda6a4e2e 380 SUPERFAMILY SSF54826 1 126 5.17E-32 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS20110 a664996eb7946cb61e9530f6fdb13feb 275 SUPERFAMILY SSF103088 156 262 1.15E-15 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS20110 a664996eb7946cb61e9530f6fdb13feb 275 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 55 4.7E-18 T 06-07-2017 IPR025713 Motility protein B, N-terminal domain CAK95_RS20110 a664996eb7946cb61e9530f6fdb13feb 275 Gene3D G3DSA:3.30.1330.60 150 262 6.7E-12 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS20110 a664996eb7946cb61e9530f6fdb13feb 275 Pfam PF00691 OmpA family 171 249 1.0E-6 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS00175 609f5228924be13e6e230a046253310e 184 SUPERFAMILY SSF52218 4 175 1.4E-42 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS00175 609f5228924be13e6e230a046253310e 184 Pfam PF03358 NADPH-dependent FMN reductase 3 149 4.0E-33 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS00175 609f5228924be13e6e230a046253310e 184 Gene3D G3DSA:3.40.50.360 1 182 6.7E-47 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS16840 4990b60a96a12a515b15b1016003f9c4 283 Gene3D G3DSA:3.90.850.10 64 282 1.0E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS16840 4990b60a96a12a515b15b1016003f9c4 283 SUPERFAMILY SSF56529 69 282 7.85E-58 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS16840 4990b60a96a12a515b15b1016003f9c4 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 282 2.7E-50 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS04175 96e02d6a32c1d07adfb78af8b22bdeaa 218 SUPERFAMILY SSF51391 12 201 2.49E-28 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS04175 96e02d6a32c1d07adfb78af8b22bdeaa 218 Gene3D G3DSA:3.20.20.70 6 206 1.9E-22 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS04175 96e02d6a32c1d07adfb78af8b22bdeaa 218 Pfam PF02581 Thiamine monophosphate synthase/TENI 15 189 3.0E-18 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS07930 b5ee371595f5e0aa8ee9fc23ccf00532 341 Gene3D G3DSA:3.40.190.10 110 239 2.1E-16 T 06-07-2017 CAK95_RS07930 b5ee371595f5e0aa8ee9fc23ccf00532 341 Pfam PF09084 NMT1/THI5 like 38 254 3.5E-42 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS07930 b5ee371595f5e0aa8ee9fc23ccf00532 341 SUPERFAMILY SSF53850 24 260 5.57E-39 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 SMART SM00663 237 516 7.8E-182 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF05000 RNA polymerase Rpb1, domain 4 673 755 7.8E-18 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Gene3D G3DSA:2.40.40.20 419 491 5.6E-37 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Gene3D G3DSA:2.40.40.20 351 378 5.6E-37 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 16 1376 10.34 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 14 638 32.225 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 SUPERFAMILY SSF64484 17 940 0.0 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 SUPERFAMILY SSF64484 1132 1364 0.0 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1038 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF04998 RNA polymerase Rpb1, domain 5 763 1315 7.5E-70 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 346 400 1.2E-8 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 394 487 1.8E-26 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF04997 RNA polymerase Rpb1, domain 1 18 344 3.6E-88 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Gene3D G3DSA:2.40.50.100 1154 1209 2.2E-8 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Gene3D G3DSA:2.40.50.100 984 1017 2.3E-4 T 06-07-2017 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Gene3D G3DSA:1.10.1040.10 1219 1307 5.9E-4 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS21225 802976b4f8f27a737a2cb196ccc03a0f 1400 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 644 4.4E-24 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 SMART SM00421 136 193 6.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 3.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 3.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 3.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 Gene3D G3DSA:1.10.10.10 132 198 3.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 191 1.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS03145 9ef69f62af44aa0b6e32ba8545103b1b 201 SUPERFAMILY SSF46894 131 199 4.08E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 5.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 5.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 5.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 Gene3D G3DSA:1.10.10.10 17 151 7.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 SUPERFAMILY SSF46785 16 151 2.49E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 SMART SM00347 40 140 5.1E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS11760 23a6aecb45ec9d34d2155cf2f38f5f78 162 Pfam PF01047 MarR family 50 104 9.0E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS08030 c0c55ded41e1ac87999e3b7997e2b498 187 SMART SM00463 97 183 7.1E-5 T 06-07-2017 IPR002625 Smr domain CAK95_RS08030 c0c55ded41e1ac87999e3b7997e2b498 187 SUPERFAMILY SSF160443 98 183 2.48E-14 T 06-07-2017 IPR002625 Smr domain CAK95_RS08030 c0c55ded41e1ac87999e3b7997e2b498 187 Pfam PF01713 Smr domain 100 183 2.1E-21 T 06-07-2017 IPR002625 Smr domain CAK95_RS11130 c480212738604189d9b1988a3e36dc55 295 Gene3D G3DSA:3.90.226.10 206 241 7.4E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11130 c480212738604189d9b1988a3e36dc55 295 Gene3D G3DSA:3.90.226.10 28 137 7.4E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11130 c480212738604189d9b1988a3e36dc55 295 SUPERFAMILY SSF52096 170 231 2.29E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11130 c480212738604189d9b1988a3e36dc55 295 SUPERFAMILY SSF52096 28 141 2.29E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11130 c480212738604189d9b1988a3e36dc55 295 Pfam PF01343 Peptidase family S49 95 237 3.8E-26 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CAK95_RS07230 1a9413d44d6f34301ed3de4d0dae8709 245 Gene3D G3DSA:3.60.15.10 2 219 4.2E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS07230 1a9413d44d6f34301ed3de4d0dae8709 245 SUPERFAMILY SSF56281 5 233 3.77E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS08150 374913e22102654708713efa95b9140c 287 SUPERFAMILY SSF52540 23 282 1.23E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08150 374913e22102654708713efa95b9140c 287 Pfam PF13614 AAA domain 24 206 4.6E-59 T 06-07-2017 IPR025669 AAA domain CAK95_RS08150 374913e22102654708713efa95b9140c 287 Gene3D G3DSA:3.40.50.300 26 283 4.6E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19300 fa2c663acbf9e87fef4bee77dc5bd541 340 SUPERFAMILY SSF53822 74 268 1.83E-5 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS19300 fa2c663acbf9e87fef4bee77dc5bd541 340 Pfam PF04392 ABC transporter substrate binding protein 43 338 3.4E-69 T 06-07-2017 IPR007487 ABC transporter, substrate-binding protein CAK95_RS19300 fa2c663acbf9e87fef4bee77dc5bd541 340 Gene3D G3DSA:3.40.50.2300 173 303 4.1E-33 T 06-07-2017 CAK95_RS19300 fa2c663acbf9e87fef4bee77dc5bd541 340 Gene3D G3DSA:3.40.50.2300 41 172 1.9E-30 T 06-07-2017 CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 Pfam PF06742 Protein of unknown function (DUF1214) 349 457 6.6E-38 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 Gene3D G3DSA:1.10.3360.10 209 303 9.6E-18 T 06-07-2017 IPR023289 VPA0735-like domain CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 SUPERFAMILY SSF160935 40 475 1.01E-133 T 06-07-2017 CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 Gene3D G3DSA:2.60.120.600 308 476 4.0E-60 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 Gene3D G3DSA:2.60.40.1610 95 208 7.9E-21 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS05075 49db0fab4313da143f7bd65d17047b94 476 Pfam PF06863 Protein of unknown function (DUF1254) 79 209 9.0E-46 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 Pfam PF00297 Ribosomal protein L3 97 180 2.7E-13 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 34.774 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 3.5E-79 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 Gene3D G3DSA:4.10.960.10 77 158 7.4E-29 T 06-07-2017 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 Gene3D G3DSA:2.40.30.10 159 212 1.3E-10 T 06-07-2017 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 Gene3D G3DSA:2.40.30.10 3 33 1.3E-10 T 06-07-2017 CAK95_RS21265 8783cdbea59986bf16320d6fe954bd70 250 SUPERFAMILY SSF50447 1 215 3.53E-79 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK95_RS09045 e72bd8ba3e7a2272e430d141bd39cc1e 328 Gene3D G3DSA:3.40.50.150 118 186 2.6E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09045 e72bd8ba3e7a2272e430d141bd39cc1e 328 Gene3D G3DSA:3.40.50.150 35 83 2.6E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09045 e72bd8ba3e7a2272e430d141bd39cc1e 328 SUPERFAMILY SSF53335 23 82 1.73E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09045 e72bd8ba3e7a2272e430d141bd39cc1e 328 SUPERFAMILY SSF53335 117 227 1.73E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06115 8b5575546f31cd4fcdde7777e98809cf 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 3 331 4.4E-39 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS06115 8b5575546f31cd4fcdde7777e98809cf 342 SUPERFAMILY SSF51726 5 338 2.35E-68 T 06-07-2017 CAK95_RS06115 8b5575546f31cd4fcdde7777e98809cf 342 Gene3D G3DSA:3.20.20.210 2 338 1.2E-81 T 06-07-2017 CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 SUPERFAMILY SSF55781 80 267 1.5E-32 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 Gene3D G3DSA:1.10.10.10 24 93 4.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 SUPERFAMILY SSF46785 24 94 1.33E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 SMART SM00346 23 112 3.1E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 Gene3D G3DSA:3.30.450.40 94 261 2.0E-34 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 Pfam PF09339 IclR helix-turn-helix domain 25 73 2.2E-7 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS19260 9503cd31b9b7e60def9f8df3fb90184b 273 Pfam PF01614 Bacterial transcriptional regulator 143 265 2.4E-16 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS15040 95056820f37c0d368607b007d654b22b 285 SUPERFAMILY SSF103481 186 283 1.44E-5 T 06-07-2017 CAK95_RS15040 95056820f37c0d368607b007d654b22b 285 SUPERFAMILY SSF103481 45 137 3.14E-7 T 06-07-2017 CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 Gene3D G3DSA:3.40.50.720 185 270 5.3E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 62 515 5.7E-140 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 Pfam PF13727 CoA-binding domain 104 284 1.4E-54 T 06-07-2017 CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 Pfam PF02397 Bacterial sugar transferase 320 509 4.0E-52 T 06-07-2017 IPR003362 Bacterial sugar transferase CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 63 515 2.4E-147 T 06-07-2017 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 CAK95_RS22585 66e8472697d3129947fad64f6b9bfc06 515 SUPERFAMILY SSF51735 186 274 3.39E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 269 6.1E-56 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 SUPERFAMILY SSF56219 3 270 2.75E-69 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 262 1.1E-24 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 Gene3D G3DSA:3.60.10.10 2 270 3.4E-69 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 06-07-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CAK95_RS08210 bc0cff1959e9e7c982d8b0a686d7f331 271 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 269 2.8E-55 T 06-07-2017 CAK95_RS27535 f8c7a0f0363b6f32be527da77889305a 435 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 431 1.8E-82 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS27535 f8c7a0f0363b6f32be527da77889305a 435 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 15 428 1.1E-69 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS27535 f8c7a0f0363b6f32be527da77889305a 435 PIRSF PIRSF006066 5 435 5.7E-73 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 16 317 51.349 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 105 1.2E-15 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 Pfam PF00589 Phage integrase family 154 302 7.4E-34 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 SUPERFAMILY SSF56349 126 315 2.27E-46 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 SUPERFAMILY SSF47823 21 106 4.32E-9 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 Gene3D G3DSA:1.10.150.130 19 106 1.6E-20 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS07445 d3290b95a99661c9c2deee91c6fba262 317 Gene3D G3DSA:1.10.443.10 153 310 5.0E-46 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS12845 d3a6740ee519897f264f4aa30ec4e5f5 130 TIGRFAM TIGR00494 crcB: protein CrcB 5 123 9.5E-30 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK95_RS12845 d3a6740ee519897f264f4aa30ec4e5f5 130 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 124 20.398 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK95_RS12845 d3a6740ee519897f264f4aa30ec4e5f5 130 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 119 1.8E-25 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 Pfam PF03600 Citrate transporter 18 537 4.4E-37 T 06-07-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 SUPERFAMILY SSF116726 302 384 9.68E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 Gene3D G3DSA:3.30.70.1450 306 388 1.7E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 Gene3D G3DSA:3.30.70.1450 215 294 2.6E-18 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 SUPERFAMILY SSF116726 212 290 4.71E-17 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK95_RS18530 2643ae3c9f5a00488ce56ad0a81a1df9 593 Pfam PF02080 TrkA-C domain 220 284 3.9E-13 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK95_RS19250 af11f82f4ad7578b9536b5149ae536db 263 SUPERFAMILY SSF52540 74 181 7.44E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19250 af11f82f4ad7578b9536b5149ae536db 263 PIRSF PIRSF034285 7 262 7.5E-49 T 06-07-2017 IPR017026 Inducible mutagenesis protein A CAK95_RS19250 af11f82f4ad7578b9536b5149ae536db 263 Gene3D G3DSA:3.40.50.300 103 181 9.6E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 Gene3D G3DSA:3.10.105.10 294 492 9.9E-33 T 06-07-2017 CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 Gene3D G3DSA:3.90.76.10 43 191 4.3E-32 T 06-07-2017 CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 Gene3D G3DSA:3.40.190.10 192 293 2.6E-20 T 06-07-2017 CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 SUPERFAMILY SSF53850 25 513 4.81E-100 T 06-07-2017 CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 PIRSF PIRSF002741 1 526 3.4E-75 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS13675 c0fbd1c26e1b3bb5c418b34e84d3114d 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 421 1.3E-62 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS12700 c35256d100a6465cfa4a9a1d53b0d342 393 Gene3D G3DSA:3.20.20.210 8 372 3.9E-60 T 06-07-2017 CAK95_RS12700 c35256d100a6465cfa4a9a1d53b0d342 393 SUPERFAMILY SSF51726 12 372 1.57E-52 T 06-07-2017 CAK95_RS12700 c35256d100a6465cfa4a9a1d53b0d342 393 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 10 355 3.1E-24 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS18445 0526e85c9e86288f25f77fcefccd27d2 388 SUPERFAMILY SSF51726 12 380 1.96E-53 T 06-07-2017 CAK95_RS18445 0526e85c9e86288f25f77fcefccd27d2 388 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 96 2.1E-7 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS18445 0526e85c9e86288f25f77fcefccd27d2 388 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 183 356 2.5E-7 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS18445 0526e85c9e86288f25f77fcefccd27d2 388 Gene3D G3DSA:3.20.20.210 8 386 1.1E-67 T 06-07-2017 CAK95_RS06130 0eaaf098b140debb0cc19060f2fb5fd0 169 SUPERFAMILY SSF51182 13 162 2.05E-32 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS06130 0eaaf098b140debb0cc19060f2fb5fd0 169 Gene3D G3DSA:2.60.120.480 12 165 4.7E-24 T 06-07-2017 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CAK95_RS06130 0eaaf098b140debb0cc19060f2fb5fd0 169 Pfam PF04115 Ureidoglycolate lyase 67 139 1.4E-4 T 06-07-2017 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CAK95_RS16595 f1e2bc6dff559bd286aa03029862a81f 462 SUPERFAMILY SSF75304 5 452 4.06E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16595 f1e2bc6dff559bd286aa03029862a81f 462 Gene3D G3DSA:3.90.1300.10 6 460 1.0E-120 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16595 f1e2bc6dff559bd286aa03029862a81f 462 Pfam PF01425 Amidase 31 443 3.0E-94 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS17295 11bcc7d6c75ebbb92dbf6a164223fe76 535 Pfam PF02653 Branched-chain amino acid transport system / permease component 245 517 1.8E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS17295 11bcc7d6c75ebbb92dbf6a164223fe76 535 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 241 531 1.6E-128 T 06-07-2017 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CAK95_RS07250 6f074e02084368977d3b95416bd76923 206 Pfam PF04191 Phospholipid methyltransferase 70 138 8.3E-11 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Gene3D G3DSA:2.150.10.10 1599 1780 1.5E-34 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 SUPERFAMILY SSF51120 1501 1629 6.28E-23 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1704 1722 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1526 1544 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1677 1695 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1535 1553 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Gene3D G3DSA:3.60.21.10 822 1162 2.0E-56 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1644 1661 21.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1576 1591 0.097 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1717 1732 0.014 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1663 1679 0.0023 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1538 1555 0.0094 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1502 1519 41.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1699 1715 0.009 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1681 1697 0.095 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1557 1573 0.65 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1521 1537 21.0 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 SUPERFAMILY SSF56219 489 820 3.6E-33 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1668 1686 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1713 1731 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 SUPERFAMILY SSF51120 1682 1804 3.01E-23 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Gene3D G3DSA:3.60.10.10 490 818 3.3E-28 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 SUPERFAMILY SSF55816 1216 1427 8.5E-26 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF02872 5'-nucleotidase, C-terminal domain 1218 1414 1.6E-17 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1544 1562 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1695 1713 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 493 811 9.2E-12 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1686 1704 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 Gene3D G3DSA:3.90.780.10 1217 1435 7.8E-33 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 SUPERFAMILY SSF56300 828 1155 3.04E-38 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 PRINTS PR00313 NodO calcium binding signature 1717 1725 1.5E-10 T 06-07-2017 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 PRINTS PR00313 NodO calcium binding signature 1687 1698 1.5E-10 T 06-07-2017 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 PRINTS PR00313 NodO calcium binding signature 1726 1735 1.5E-10 T 06-07-2017 CAK95_RS21065 16821f5174c0e946a69f87491bab0630 1831 PRINTS PR00313 NodO calcium binding signature 1699 1707 1.5E-10 T 06-07-2017 CAK95_RS05890 ffd4c5b1ffd0443c38c5e79966a2a1c7 335 SUPERFAMILY SSF53850 11 323 3.8E-61 T 06-07-2017 CAK95_RS05890 ffd4c5b1ffd0443c38c5e79966a2a1c7 335 Gene3D G3DSA:3.40.190.10 12 152 5.9E-24 T 06-07-2017 CAK95_RS05890 ffd4c5b1ffd0443c38c5e79966a2a1c7 335 Gene3D G3DSA:3.40.190.10 153 274 2.1E-14 T 06-07-2017 CAK95_RS05890 ffd4c5b1ffd0443c38c5e79966a2a1c7 335 Pfam PF12849 PBP superfamily domain 5 287 1.4E-33 T 06-07-2017 IPR024370 PBP domain CAK95_RS19970 620db1e1e5e182abab9603c651c3bde8 373 Pfam PF11064 Protein of unknown function (DUF2865) 201 312 2.6E-39 T 06-07-2017 IPR021293 Protein of unknown function DUF2865 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 Gene3D G3DSA:3.30.930.10 18 168 6.7E-47 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 Gene3D G3DSA:3.30.930.10 204 205 6.7E-47 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 Gene3D G3DSA:3.30.930.10 292 374 6.7E-47 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 SUPERFAMILY SSF55681 259 375 2.94E-43 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 SUPERFAMILY SSF55681 18 175 2.94E-43 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 Pfam PF13393 Histidyl-tRNA synthetase 293 374 1.6E-12 T 06-07-2017 CAK95_RS13245 fb16aac2f6be53dd597898f37ffa8a6a 379 Pfam PF13393 Histidyl-tRNA synthetase 16 191 3.0E-26 T 06-07-2017 CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 SUPERFAMILY SSF52540 21 240 1.41E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 SUPERFAMILY SSF52540 285 501 7.84E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 SMART SM00382 46 232 1.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 Pfam PF00005 ABC transporter 289 441 6.8E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 Pfam PF00005 ABC transporter 38 185 3.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 Gene3D G3DSA:3.40.50.300 21 247 5.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16610 8cc9617b11896f2316951bb734ebcf00 527 Gene3D G3DSA:3.40.50.300 287 500 7.0E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22795 65987ffcfec8cf3de790fac2998d3bda 571 SUPERFAMILY SSF53649 279 423 8.94E-10 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS22795 65987ffcfec8cf3de790fac2998d3bda 571 Gene3D G3DSA:3.40.720.10 287 462 5.0E-7 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS22795 65987ffcfec8cf3de790fac2998d3bda 571 Pfam PF00884 Sulfatase 281 463 3.9E-8 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS11475 996d4faf01d1a0b7ae91d8a5442f251c 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 316 3.8E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11475 996d4faf01d1a0b7ae91d8a5442f251c 316 SUPERFAMILY SSF161098 97 303 3.43E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11475 996d4faf01d1a0b7ae91d8a5442f251c 316 Gene3D G3DSA:1.10.3720.10 97 312 9.0E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21785 71ff417d42fd447bd8a05397fc86ea62 275 Pfam PF02698 DUF218 domain 80 245 1.9E-29 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAK95_RS21785 71ff417d42fd447bd8a05397fc86ea62 275 Gene3D G3DSA:3.40.50.620 77 214 6.5E-27 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS16930 ac6d48847f0a51fc8089e55867043a69 168 SMART SM00903 22 167 3.3E-31 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS16930 ac6d48847f0a51fc8089e55867043a69 168 SUPERFAMILY SSF50475 10 167 2.7E-36 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS16930 ac6d48847f0a51fc8089e55867043a69 168 Gene3D G3DSA:2.30.110.10 8 167 2.8E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS16930 ac6d48847f0a51fc8089e55867043a69 168 Pfam PF01613 Flavin reductase like domain 25 168 4.8E-29 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 Gene3D G3DSA:1.20.1050.10 102 236 4.7E-5 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 Gene3D G3DSA:3.40.30.10 42 101 1.7E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 Pfam PF17171 Glutathione S-transferase, C-terminal domain 174 235 2.7E-18 T 06-07-2017 IPR033468 Metaxin, glutathione S-transferase domain CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 SUPERFAMILY SSF52833 26 110 2.15E-11 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 Pfam PF17172 Glutathione S-transferase N-terminal domain 28 123 2.5E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS13855 3ee3e06769e26c8a93b717b390d81885 251 SUPERFAMILY SSF47616 170 243 9.61E-8 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS00475 7d914652feae33fe82e66ec256a3a30c 372 Pfam PF02445 Quinolinate synthetase A protein 79 369 9.7E-114 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK95_RS00475 7d914652feae33fe82e66ec256a3a30c 372 Hamap MF_00568 Quinolinate synthase A [nadA]. 74 370 45.143 T 06-07-2017 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK95_RS00475 7d914652feae33fe82e66ec256a3a30c 372 SUPERFAMILY SSF142754 76 370 2.22E-110 T 06-07-2017 CAK95_RS00475 7d914652feae33fe82e66ec256a3a30c 372 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 76 370 2.6E-102 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 Pfam PF13602 Zinc-binding dehydrogenase 194 334 9.0E-19 T 06-07-2017 CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 SUPERFAMILY SSF50129 13 146 1.21E-29 T 06-07-2017 IPR011032 GroES-like CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 SUPERFAMILY SSF51735 117 287 3.47E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 Gene3D G3DSA:3.40.50.720 159 247 7.2E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 337 1.0E-170 T 06-07-2017 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 Gene3D G3DSA:3.90.180.10 1 158 4.2E-32 T 06-07-2017 IPR011032 GroES-like CAK95_RS21400 05c2c6ec58da1db54e45585d6a1aab87 338 SMART SM00829 13 334 4.4E-10 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS06160 57309f5d7b10055ff464f9b5e98d932c 233 SUPERFAMILY SSF49482 9 228 1.57E-70 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS06160 57309f5d7b10055ff464f9b5e98d932c 233 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 14 229 1.4E-109 T 06-07-2017 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS06160 57309f5d7b10055ff464f9b5e98d932c 233 Pfam PF00775 Dioxygenase 44 224 2.8E-50 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS06160 57309f5d7b10055ff464f9b5e98d932c 233 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 5 39 1.9E-13 T 06-07-2017 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS06160 57309f5d7b10055ff464f9b5e98d932c 233 Gene3D G3DSA:2.60.130.10 17 229 8.3E-70 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS25305 c1b2d207336122c2519dfd6c0960878a 329 PIRSF PIRSF017082 3 327 7.0E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25305 c1b2d207336122c2519dfd6c0960878a 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 325 6.7E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25305 c1b2d207336122c2519dfd6c0960878a 329 SUPERFAMILY SSF53850 113 291 2.06E-10 T 06-07-2017 CAK95_RS21090 e810e6c1a5dc6804df8ec5c0b7bf8f0a 443 Gene3D G3DSA:3.40.190.10 193 310 5.7E-13 T 06-07-2017 CAK95_RS21090 e810e6c1a5dc6804df8ec5c0b7bf8f0a 443 Pfam PF13379 NMT1-like family 86 323 9.1E-75 T 06-07-2017 CAK95_RS21090 e810e6c1a5dc6804df8ec5c0b7bf8f0a 443 SUPERFAMILY SSF53850 87 311 1.68E-34 T 06-07-2017 CAK95_RS20180 5a19b350a8fa2bf7da794e5570c76ddb 415 Gene3D G3DSA:3.40.50.1820 202 270 1.6E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20180 5a19b350a8fa2bf7da794e5570c76ddb 415 SUPERFAMILY SSF53474 312 324 4.93E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20180 5a19b350a8fa2bf7da794e5570c76ddb 415 SUPERFAMILY SSF53474 203 276 4.93E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09250 f85769a657bc4546f87505fe4d962584 164 Pfam PF00582 Universal stress protein family 17 152 7.8E-7 T 06-07-2017 IPR006016 UspA GO:0006950 CAK95_RS09250 f85769a657bc4546f87505fe4d962584 164 SUPERFAMILY SSF52402 15 153 1.84E-11 T 06-07-2017 CAK95_RS09250 f85769a657bc4546f87505fe4d962584 164 Gene3D G3DSA:3.40.50.620 15 152 2.1E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS24475 d32a854e9acfe5c1268c8ce490937083 581 Pfam PF03354 Phage Terminase 75 564 6.9E-53 T 06-07-2017 IPR005021 Phage terminase CAK95_RS09355 6e961131fda6bcf881bb1183aca7bc96 97 Gene3D G3DSA:1.10.10.60 38 86 2.8E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS09355 6e961131fda6bcf881bb1183aca7bc96 97 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 40 85 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS09355 6e961131fda6bcf881bb1183aca7bc96 97 Pfam PF12833 Helix-turn-helix domain 10 86 4.4E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS09355 6e961131fda6bcf881bb1183aca7bc96 97 SMART SM00342 4 89 7.4E-13 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS09355 6e961131fda6bcf881bb1183aca7bc96 97 SUPERFAMILY SSF46689 40 88 3.14E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS19335 72923daaa6422e803e4c9dc84d94e0f7 1301 Pfam PF02514 CobN/Magnesium Chelatase 133 1186 3.7E-286 T 06-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 CAK95_RS01315 bd51fb9d483fb8363a346a779336d582 411 Gene3D G3DSA:1.20.1250.20 28 204 4.8E-21 T 06-07-2017 CAK95_RS01315 bd51fb9d483fb8363a346a779336d582 411 Gene3D G3DSA:1.20.1250.20 227 402 1.4E-18 T 06-07-2017 CAK95_RS01315 bd51fb9d483fb8363a346a779336d582 411 Pfam PF07690 Major Facilitator Superfamily 33 270 8.3E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS01315 bd51fb9d483fb8363a346a779336d582 411 SUPERFAMILY SSF103473 26 402 1.19E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS13270 1387dc45993eefe9ee12e8d8e67aa941 325 SUPERFAMILY SSF53448 1 210 5.25E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS13270 1387dc45993eefe9ee12e8d8e67aa941 325 Gene3D G3DSA:3.90.550.10 1 176 3.7E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS13270 1387dc45993eefe9ee12e8d8e67aa941 325 Pfam PF00535 Glycosyl transferase family 2 7 167 1.0E-31 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS04100 791a5550d373d3a5e46e018dcfa8d187 328 Pfam PF00753 Metallo-beta-lactamase superfamily 98 283 2.6E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04100 791a5550d373d3a5e46e018dcfa8d187 328 Gene3D G3DSA:3.60.15.10 36 319 1.2E-56 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04100 791a5550d373d3a5e46e018dcfa8d187 328 SUPERFAMILY SSF56281 34 322 2.36E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04100 791a5550d373d3a5e46e018dcfa8d187 328 SMART SM00849 97 301 3.9E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 Gene3D G3DSA:3.40.50.980 90 253 2.5E-11 T 06-07-2017 CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 Pfam PF00501 AMP-binding enzyme 84 292 2.0E-14 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 PIRSF PIRSF006444 4 435 3.3E-208 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 Gene3D G3DSA:3.30.300.30 329 434 2.9E-33 T 06-07-2017 CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 SUPERFAMILY SSF56801 20 397 1.01E-62 T 06-07-2017 CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 433 5.7E-24 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal CAK95_RS17395 c58b53273571ca198dcac98aa5eef6fb 435 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 15 433 5.7E-217 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 Pfam PF01614 Bacterial transcriptional regulator 105 222 3.0E-16 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 Gene3D G3DSA:3.30.450.40 58 225 2.4E-24 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 Gene3D G3DSA:1.10.10.10 1 50 1.3E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 SUPERFAMILY SSF55781 58 225 3.07E-25 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 SUPERFAMILY SSF46785 2 49 1.66E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01465 ca67a7e068427d9de28217413e9d8fea 227 Pfam PF09339 IclR helix-turn-helix domain 1 32 5.8E-7 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS27590 04f6fa535a5a861b1f75fcb266959db4 200 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 198 35.973 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK95_RS27590 04f6fa535a5a861b1f75fcb266959db4 200 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 197 8.2E-63 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK95_RS27590 04f6fa535a5a861b1f75fcb266959db4 200 Pfam PF02669 K+-transporting ATPase, c chain 6 197 1.6E-71 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK95_RS27590 04f6fa535a5a861b1f75fcb266959db4 200 PIRSF PIRSF001296 1 200 1.3E-74 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 121 134 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 197 210 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 110 118 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 288 302 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 401 414 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 135 150 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 211 224 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 84 97 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 PRINTS PR00415 Aconitase family signature 345 356 4.6E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 1.6E-154 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 SUPERFAMILY SSF53732 3 467 5.1E-166 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 468 60.577 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Gene3D G3DSA:3.30.499.10 337 467 3.6E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Gene3D G3DSA:3.30.499.10 295 305 3.6E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Gene3D G3DSA:3.30.499.10 2 160 1.1E-25 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 466 8.1E-239 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAK95_RS07680 5ed345cf8e85b315376eee18e92e4a8c 468 Gene3D G3DSA:3.40.1060.10 169 283 2.1E-40 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS21605 9d5e4d129ec73db0b83d4891df43552f 140 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 116 1.7E-23 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS21605 9d5e4d129ec73db0b83d4891df43552f 140 Gene3D G3DSA:3.90.1590.10 2 136 5.7E-38 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS21605 9d5e4d129ec73db0b83d4891df43552f 140 SUPERFAMILY SSF51316 1 137 1.78E-41 T 06-07-2017 IPR011057 Mss4-like CAK95_RS28645 e6dadd0d906280b43b3779ae74e2906d 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 248 1.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28645 e6dadd0d906280b43b3779ae74e2906d 265 Gene3D G3DSA:1.10.3720.10 48 245 1.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28645 e6dadd0d906280b43b3779ae74e2906d 265 SUPERFAMILY SSF161098 55 241 1.03E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 Gene3D G3DSA:3.10.20.30 22 128 2.9E-42 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 Pfam PF13534 4Fe-4S dicluster domain 169 242 9.4E-9 T 06-07-2017 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 251 1.5E-76 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 Gene3D G3DSA:1.10.1060.10 130 258 3.4E-49 T 06-07-2017 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 30 133 4.5E-32 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 SUPERFAMILY SSF54292 28 128 1.12E-30 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS07850 c484fb0054f100ceecb59fe19d79f839 259 SUPERFAMILY SSF46548 130 257 4.19E-35 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 Pfam PF12697 Alpha/beta hydrolase family 22 222 1.0E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 Gene3D G3DSA:3.40.50.1820 5 231 2.3E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 SUPERFAMILY SSF53474 4 230 1.33E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 176 190 4.0E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 73 4.0E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS24945 881a8b22e92ffe0179d72e462d381715 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 74 87 4.0E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS11650 06e861510f16f18082aeee8c91cb69d5 388 Gene3D G3DSA:3.40.50.2300 22 216 4.1E-39 T 06-07-2017 CAK95_RS11650 06e861510f16f18082aeee8c91cb69d5 388 Pfam PF13458 Periplasmic binding protein 23 357 9.1E-59 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS11650 06e861510f16f18082aeee8c91cb69d5 388 SUPERFAMILY SSF53822 23 382 8.78E-73 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS21440 a18af510cc6651281ad9b3041e648969 288 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 137 152 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK95_RS21440 a18af510cc6651281ad9b3041e648969 288 SUPERFAMILY SSF53474 22 249 3.89E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS21440 a18af510cc6651281ad9b3041e648969 288 Gene3D G3DSA:3.40.50.1820 37 268 3.6E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS21440 a18af510cc6651281ad9b3041e648969 288 Pfam PF00135 Carboxylesterase family 53 181 1.3E-20 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 278 2.4E-59 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 SUPERFAMILY SSF51735 103 278 9.05E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 SUPERFAMILY SSF52283 15 132 5.1E-16 T 06-07-2017 CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 Gene3D G3DSA:3.40.50.720 16 117 3.2E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 26 286 7.1E-6 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK95_RS16235 965a012e8382d3dcc76f7f5ed77f6aac 301 Gene3D G3DSA:3.40.50.720 118 280 3.6E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 SMART SM00327 410 612 3.6E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 399 616 1.2E-118 T 06-07-2017 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 17 618 5.8E-297 T 06-07-2017 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 SUPERFAMILY SSF53300 413 607 4.45E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 Gene3D G3DSA:3.40.50.410 413 588 1.9E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 Pfam PF06213 Cobalamin biosynthesis protein CobT 13 285 7.0E-101 T 06-07-2017 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS10535 f9359e8e7d0a199858a7666d127bef3e 635 PIRSF PIRSF031715 3 623 4.6E-278 T 06-07-2017 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS22665 a580f138d3cc04cb0a3466a7d000e1bd 411 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 376 6.2E-48 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS22665 a580f138d3cc04cb0a3466a7d000e1bd 411 Pfam PF00990 Diguanylate cyclase, GGDEF domain 217 373 2.1E-43 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS22665 a580f138d3cc04cb0a3466a7d000e1bd 411 Gene3D G3DSA:3.30.70.270 219 378 2.7E-51 T 06-07-2017 CAK95_RS22665 a580f138d3cc04cb0a3466a7d000e1bd 411 SMART SM00267 205 377 4.4E-51 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS22665 a580f138d3cc04cb0a3466a7d000e1bd 411 SUPERFAMILY SSF55073 222 376 4.79E-44 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS26930 c0b27b33922c0739e6c20018080a2ed4 254 Pfam PF08003 Protein of unknown function (DUF1698) 3 215 7.0E-12 T 06-07-2017 IPR027555 tRNA (mo5U34)-methyltransferase-like CAK95_RS26930 c0b27b33922c0739e6c20018080a2ed4 254 SUPERFAMILY SSF53335 52 219 7.26E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26930 c0b27b33922c0739e6c20018080a2ed4 254 Gene3D G3DSA:3.40.50.150 52 222 3.9E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 Hamap MF_00970 Ribonuclease E [rne]. 2 1038 31.466 T 06-07-2017 IPR028878 Ribonuclease E GO:0006396|GO:0008995 CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 340 690 3.9E-134 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 Gene3D G3DSA:2.40.50.140 349 391 5.3E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 Gene3D G3DSA:2.40.50.140 31 83 5.3E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 Pfam PF10150 Ribonuclease E/G family 387 658 9.5E-95 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 Pfam PF00575 S1 RNA binding domain 40 92 1.8E-4 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK95_RS25140 eb30758822eab549d256702110ea9c86 1039 SUPERFAMILY SSF50249 40 83 8.72E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS06020 ce765aea5d7b41200af5af25bd9fa7ea 423 SUPERFAMILY SSF103473 15 418 1.19E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS06020 ce765aea5d7b41200af5af25bd9fa7ea 423 Gene3D G3DSA:1.20.1250.20 236 416 4.1E-20 T 06-07-2017 CAK95_RS06020 ce765aea5d7b41200af5af25bd9fa7ea 423 Gene3D G3DSA:1.20.1250.20 17 217 8.9E-22 T 06-07-2017 CAK95_RS06020 ce765aea5d7b41200af5af25bd9fa7ea 423 Pfam PF00083 Sugar (and other) transporter 20 219 9.9E-18 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK95_RS06020 ce765aea5d7b41200af5af25bd9fa7ea 423 Pfam PF07690 Major Facilitator Superfamily 242 415 1.3E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS28840 fa32b9b07e91404a6890c88e05cec174 93 Gene3D G3DSA:3.40.50.10540 44 83 4.1E-13 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS28840 fa32b9b07e91404a6890c88e05cec174 93 SUPERFAMILY SSF89796 44 87 4.58E-13 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS28840 fa32b9b07e91404a6890c88e05cec174 93 Pfam PF02515 CoA-transferase family III 44 85 3.9E-12 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS00430 034619516367f876cb2424d90c108066 299 Gene3D G3DSA:3.40.50.1820 52 277 1.7E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00430 034619516367f876cb2424d90c108066 299 SUPERFAMILY SSF53474 54 270 2.63E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00430 034619516367f876cb2424d90c108066 299 Pfam PF07859 alpha/beta hydrolase fold 86 172 7.8E-10 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS25070 af0b57b2b17bdaf5d59424301032415f 159 Pfam PF08818 Domain of unknown function (DU1801) 41 141 8.6E-19 T 06-07-2017 IPR014922 Domain of unknown function DUF1801 CAK95_RS25070 af0b57b2b17bdaf5d59424301032415f 159 SUPERFAMILY SSF159888 29 145 1.96E-17 T 06-07-2017 CAK95_RS09055 6f3148cc8d776a39aaf0a3415a635e38 388 Gene3D G3DSA:3.40.50.2000 150 357 7.4E-18 T 06-07-2017 CAK95_RS09055 6f3148cc8d776a39aaf0a3415a635e38 388 SUPERFAMILY SSF53756 3 379 6.6E-64 T 06-07-2017 CAK95_RS09055 6f3148cc8d776a39aaf0a3415a635e38 388 Pfam PF13439 Glycosyltransferase Family 4 13 165 1.0E-21 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS09055 6f3148cc8d776a39aaf0a3415a635e38 388 Pfam PF13692 Glycosyl transferases group 1 191 342 1.6E-18 T 06-07-2017 CAK95_RS18135 805695f4b7134fceddde8a78e58c210a 121 Pfam PF07309 Flagellar protein FlaF 5 117 8.9E-36 T 06-07-2017 IPR010845 Flagellar FlaF GO:0044781 CAK95_RS08580 72180cbc3fa4e8f366ff07f3888a1dec 287 SUPERFAMILY SSF53474 23 274 3.13E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08580 72180cbc3fa4e8f366ff07f3888a1dec 287 Pfam PF00561 alpha/beta hydrolase fold 53 152 2.5E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08580 72180cbc3fa4e8f366ff07f3888a1dec 287 Gene3D G3DSA:3.40.50.1820 15 279 5.0E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 SUPERFAMILY SSF52540 67 293 9.77E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 Gene3D G3DSA:3.40.50.300 66 278 6.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 3 432 4.3E-165 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 SMART SM00382 90 245 2.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 Gene3D G3DSA:3.30.230.10 285 435 7.1E-30 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 Pfam PF13481 AAA domain 85 223 6.9E-16 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 Hamap MF_01498 DNA repair protein RadA [radA]. 21 457 43.279 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 Pfam PF13541 Subunit ChlI of Mg-chelatase 340 428 1.4E-7 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 175 199 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 323 346 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 124 141 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 249 275 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 10 34 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 214 242 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 PRINTS PR01874 DNA repair protein radA signature 82 110 7.1E-89 T 06-07-2017 CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 SUPERFAMILY SSF54211 256 270 9.1E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS25950 8563d3c8062faece5e0af865a96b9342 469 SUPERFAMILY SSF54211 304 449 9.1E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 SUPERFAMILY SSF48498 83 206 7.83E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 SUPERFAMILY SSF46689 4 81 2.82E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14885 322ad5501b4058f968082696079eb96e 228 Gene3D G3DSA:1.10.357.10 6 204 2.0E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 13 95 1.4E-21 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Gene3D G3DSA:1.10.150.130 11 103 1.9E-27 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 9 312 56.193 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Pfam PF00589 Phage integrase family 143 297 5.3E-42 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Gene3D G3DSA:1.10.443.10 132 305 2.0E-48 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 SUPERFAMILY SSF56349 13 303 5.59E-54 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS10490 8982e3c0657348c08e345ac7775a56f4 322 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 312 51.876 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAK95_RS11630 6728e9d833683df8d7b70dce922bf0ba 326 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 115 304 1.1E-15 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 22 213 2.2E-70 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 Gene3D G3DSA:2.30.110.10 21 213 5.8E-78 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 SUPERFAMILY SSF50475 22 213 1.96E-65 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 118 5.3E-27 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 213 3.5E-17 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 1 213 38.256 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS15855 470313d1cb7c0f1e99506a40dee1dd78 213 PIRSF PIRSF000190 4 213 2.0E-71 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 140 153 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 256 270 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 154 167 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 110 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00412 Epoxide hydrolase signature 154 167 1.4E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00412 Epoxide hydrolase signature 288 310 1.4E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 PRINTS PR00412 Epoxide hydrolase signature 76 94 1.4E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 Pfam PF00561 alpha/beta hydrolase fold 70 190 1.7E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 SUPERFAMILY SSF53474 51 311 4.23E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18425 e3ab5dd86c30f10b57ae64545b95cd19 312 Gene3D G3DSA:3.40.50.1820 52 311 6.7E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06650 ec69c16f7998d1b9893a2d8b6ef4e2e7 264 Pfam PF08666 SAF domain 43 109 1.5E-7 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS06650 ec69c16f7998d1b9893a2d8b6ef4e2e7 264 SMART SM00858 42 110 2.3E-11 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS06650 ec69c16f7998d1b9893a2d8b6ef4e2e7 264 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 7 245 6.3E-75 T 06-07-2017 IPR017592 Pilus assembly, Flp-type CpaB CAK95_RS06650 ec69c16f7998d1b9893a2d8b6ef4e2e7 264 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 227 1.8E-32 T 06-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CAK95_RS16200 160862ebf00723e1cb6377469e2d3883 315 Gene3D G3DSA:3.50.30.50 83 314 3.3E-24 T 06-07-2017 CAK95_RS16200 160862ebf00723e1cb6377469e2d3883 315 SUPERFAMILY SSF102198 67 314 3.53E-19 T 06-07-2017 CAK95_RS16200 160862ebf00723e1cb6377469e2d3883 315 Pfam PF04199 Putative cyclase 91 246 3.2E-19 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS12005 0d7ca893eed73d8873db3edfcb14779b 168 SUPERFAMILY SSF55961 3 167 7.07E-41 T 06-07-2017 CAK95_RS12005 0d7ca893eed73d8873db3edfcb14779b 168 Gene3D G3DSA:3.30.530.20 4 167 3.5E-47 T 06-07-2017 IPR023393 START-like domain CAK95_RS12005 0d7ca893eed73d8873db3edfcb14779b 168 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 165 7.9E-25 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 261 7.8E-65 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 Gene3D G3DSA:3.90.226.10 3 203 1.6E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 Gene3D G3DSA:1.10.12.10 204 262 6.6E-20 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 6 262 4.4E-119 T 06-07-2017 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 CAK95_RS17405 7dde1fdce07426dfdff9c65f76f31e49 265 SUPERFAMILY SSF52096 1 262 6.64E-83 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS14245 b5a8a69462a1f91579e8985b81283ce6 215 SUPERFAMILY SSF52540 1 172 3.47E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14245 b5a8a69462a1f91579e8985b81283ce6 215 Gene3D G3DSA:3.40.50.300 1 164 5.4E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14245 b5a8a69462a1f91579e8985b81283ce6 215 ProSitePatterns PS00211 ABC transporters family signature. 90 104 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS14245 b5a8a69462a1f91579e8985b81283ce6 215 Pfam PF00005 ABC transporter 1 117 2.2E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS04590 081ef3d312b8fd4d21e6392cdd06e3fe 354 Gene3D G3DSA:1.20.1090.10 160 346 4.1E-47 T 06-07-2017 CAK95_RS04590 081ef3d312b8fd4d21e6392cdd06e3fe 354 SUPERFAMILY SSF56796 8 349 4.84E-87 T 06-07-2017 CAK95_RS04590 081ef3d312b8fd4d21e6392cdd06e3fe 354 Gene3D G3DSA:3.40.50.1970 8 158 1.8E-29 T 06-07-2017 CAK95_RS04590 081ef3d312b8fd4d21e6392cdd06e3fe 354 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 334 1.4E-77 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAK95_RS23270 e5b2459d345d9249026661c1af91688a 285 Gene3D G3DSA:3.30.470.10 4 118 1.4E-33 T 06-07-2017 CAK95_RS23270 e5b2459d345d9249026661c1af91688a 285 Gene3D G3DSA:3.20.10.10 128 282 8.6E-45 T 06-07-2017 CAK95_RS23270 e5b2459d345d9249026661c1af91688a 285 SUPERFAMILY SSF56752 2 280 1.16E-71 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK95_RS23270 e5b2459d345d9249026661c1af91688a 285 Pfam PF01063 Amino-transferase class IV 31 257 2.7E-45 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 145 1.4E-38 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 SUPERFAMILY SSF55653 57 146 1.12E-23 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 3.2E-23 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 Gene3D G3DSA:3.40.5.10 1 52 1.7E-23 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 7.8E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 24.151 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 SUPERFAMILY SSF55658 1 57 7.85E-18 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CAK95_RS25925 31ff05f92f3bb5e2ce5d5798e42450cd 202 Gene3D G3DSA:3.10.430.100 61 147 5.0E-25 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK95_RS14760 08702b004e63d38915c8f2c58ef9cc54 337 Pfam PF13379 NMT1-like family 26 265 3.7E-23 T 06-07-2017 CAK95_RS14760 08702b004e63d38915c8f2c58ef9cc54 337 SUPERFAMILY SSF53850 25 275 6.95E-36 T 06-07-2017 CAK95_RS14760 08702b004e63d38915c8f2c58ef9cc54 337 SMART SM00062 27 257 0.0071 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS14760 08702b004e63d38915c8f2c58ef9cc54 337 Gene3D G3DSA:3.40.190.10 112 240 5.4E-16 T 06-07-2017 CAK95_RS11830 3d5c27009075b54f3bce55ad53abcedb 261 Gene3D G3DSA:1.10.1670.10 153 205 3.5E-13 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK95_RS11830 3d5c27009075b54f3bce55ad53abcedb 261 SUPERFAMILY SSF48150 35 204 5.58E-35 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS11830 3d5c27009075b54f3bce55ad53abcedb 261 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 49 185 4.7E-11 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS11830 3d5c27009075b54f3bce55ad53abcedb 261 SMART SM00478 52 205 4.3E-5 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS11830 3d5c27009075b54f3bce55ad53abcedb 261 Gene3D G3DSA:1.10.340.30 44 151 1.1E-23 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 SUPERFAMILY SSF51604 139 422 6.94E-126 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.0E-205 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 311 322 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 161 174 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 37 51 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 107 123 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 334 348 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PRINTS PR00148 Enolase signature 363 380 3.5E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 Gene3D G3DSA:3.30.390.10 4 125 1.1E-53 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 Gene3D G3DSA:3.20.20.120 128 424 4.4E-134 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 Hamap MF_00318 Enolase [eno]. 2 411 44.073 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 423 4.7E-130 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 Pfam PF03952 Enolase, N-terminal domain 4 134 1.6E-57 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 SMART SM01192 139 425 1.6E-221 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 SUPERFAMILY SSF54826 4 136 5.66E-55 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 SMART SM01193 4 134 2.7E-92 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS23155 9259702424d3496a7bc75ffb087a4fb1 427 PIRSF PIRSF001400 1 425 1.4E-187 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS26605 02e0e17d37507e4ea16ba2ea7af2d53f 201 SUPERFAMILY SSF53335 11 193 1.81E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26605 02e0e17d37507e4ea16ba2ea7af2d53f 201 Pfam PF13649 Methyltransferase domain 40 135 3.8E-16 T 06-07-2017 CAK95_RS26605 02e0e17d37507e4ea16ba2ea7af2d53f 201 Gene3D G3DSA:3.40.50.150 24 148 5.7E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11385 065c9b0e45344d2176f306b3d8ed32e8 320 SUPERFAMILY SSF51556 8 320 2.59E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS11385 065c9b0e45344d2176f306b3d8ed32e8 320 Pfam PF04909 Amidohydrolase 16 320 2.9E-47 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS11385 065c9b0e45344d2176f306b3d8ed32e8 320 Gene3D G3DSA:3.20.20.140 9 320 2.0E-83 T 06-07-2017 CAK95_RS22360 c0588ba8457ec16b3ade441a45ff6f1e 415 Pfam PF05559 Protein of unknown function (DUF763) 6 331 8.4E-130 T 06-07-2017 IPR008482 Protein of unknown function DUF763 CAK95_RS25660 dbc26e5164eb8f11225559dfa55eb5d3 227 SUPERFAMILY SSF46785 8 121 3.08E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25660 dbc26e5164eb8f11225559dfa55eb5d3 227 Gene3D G3DSA:1.10.10.10 6 91 1.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25660 dbc26e5164eb8f11225559dfa55eb5d3 227 SMART SM00418 9 88 5.4E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS25660 dbc26e5164eb8f11225559dfa55eb5d3 227 Pfam PF12840 Helix-turn-helix domain 10 68 9.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00190 f69458607b5360750a9043cb20acaeea 343 Pfam PF13379 NMT1-like family 37 277 2.0E-9 T 06-07-2017 CAK95_RS00190 f69458607b5360750a9043cb20acaeea 343 SUPERFAMILY SSF53850 39 275 2.08E-22 T 06-07-2017 CAK95_RS00190 f69458607b5360750a9043cb20acaeea 343 Gene3D G3DSA:3.40.190.10 51 153 5.2E-4 T 06-07-2017 CAK95_RS01685 b80a344711b8e7898109c883eef34d26 216 Gene3D G3DSA:1.10.10.690 78 214 4.0E-29 T 06-07-2017 IPR027405 YidB-like CAK95_RS01685 b80a344711b8e7898109c883eef34d26 216 SUPERFAMILY SSF140804 102 214 4.18E-30 T 06-07-2017 IPR027405 YidB-like CAK95_RS01685 b80a344711b8e7898109c883eef34d26 216 Pfam PF06078 Bacterial protein of unknown function (DUF937) 75 203 5.4E-9 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS13110 2ad60ec32a73c3d032a48f0ffbb99bcc 361 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 50 325 3.2E-57 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS13110 2ad60ec32a73c3d032a48f0ffbb99bcc 361 PIRSF PIRSF039026 1 359 2.9E-126 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 Pfam PF01227 GTP cyclohydrolase I 30 207 1.1E-73 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 SUPERFAMILY SSF55620 22 208 1.41E-71 T 06-07-2017 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 208 3.1E-64 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 Gene3D G3DSA:3.30.1130.10 81 208 4.7E-55 T 06-07-2017 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 87 103 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 Gene3D G3DSA:1.10.286.10 24 75 2.7E-20 T 06-07-2017 CAK95_RS20830 f87244e34139bfe5703b32c9c7af473b 212 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 25 208 38.591 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 Pfam PF00318 Ribosomal protein S2 11 226 7.8E-94 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 7 226 1.0E-98 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 233 40.078 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 177 188 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 160 177 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 8 26 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 198 212 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 39 48 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 PRINTS PR00395 Ribosomal protein S2 signature 89 106 1.4E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 Gene3D G3DSA:3.40.50.10490 160 235 1.7E-62 T 06-07-2017 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 Gene3D G3DSA:3.40.50.10490 25 101 1.7E-62 T 06-07-2017 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 Gene3D G3DSA:1.10.287.610 102 154 1.2E-22 T 06-07-2017 CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 SUPERFAMILY SSF52313 8 232 1.15E-91 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain CAK95_RS22955 4a7e8ff8a8f213d600f85117b0d8aa0f 332 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 160 184 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAK95_RS13025 1d34a637b46098b53f83cde6ff7d11c0 443 Pfam PF13458 Periplasmic binding protein 30 398 4.7E-67 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS13025 1d34a637b46098b53f83cde6ff7d11c0 443 SUPERFAMILY SSF53822 30 403 2.99E-43 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS13025 1d34a637b46098b53f83cde6ff7d11c0 443 Gene3D G3DSA:3.40.50.2300 307 341 1.8E-14 T 06-07-2017 CAK95_RS13025 1d34a637b46098b53f83cde6ff7d11c0 443 Gene3D G3DSA:3.40.50.2300 26 154 1.8E-14 T 06-07-2017 CAK95_RS13025 1d34a637b46098b53f83cde6ff7d11c0 443 Gene3D G3DSA:3.40.50.2300 169 284 8.6E-9 T 06-07-2017 CAK95_RS08325 24dcb6ffd5620ecd3698759cd5611eea 427 Pfam PF00144 Beta-lactamase 57 411 5.0E-65 T 06-07-2017 IPR001466 Beta-lactamase-related CAK95_RS08325 24dcb6ffd5620ecd3698759cd5611eea 427 SUPERFAMILY SSF56601 47 413 7.45E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS08325 24dcb6ffd5620ecd3698759cd5611eea 427 Gene3D G3DSA:3.40.710.10 39 411 9.2E-83 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS23760 87c96b3d6ab530be00ecc649d008b412 491 Pfam PF02530 Porin subfamily 25 456 5.0E-70 T 06-07-2017 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 CAK95_RS18335 9474b1e80c7ab2be972df466cfebda91 219 Gene3D G3DSA:3.10.100.10 29 218 2.8E-37 T 06-07-2017 IPR016186 C-type lectin-like CAK95_RS18335 9474b1e80c7ab2be972df466cfebda91 219 SUPERFAMILY SSF56436 28 196 1.46E-32 T 06-07-2017 IPR016187 C-type lectin fold CAK95_RS24645 37a1ea8b0bb71c56aa7c3be1171b2ca7 170 Pfam PF02643 Uncharacterized ACR, COG1430 61 163 2.1E-33 T 06-07-2017 IPR003795 Protein of unknown function DUF192 CAK95_RS08945 b848b68731741965a22d61e7164afd2b 149 Pfam PF13673 Acetyltransferase (GNAT) domain 70 129 3.0E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS08945 b848b68731741965a22d61e7164afd2b 149 Gene3D G3DSA:3.40.630.30 9 148 2.9E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08945 b848b68731741965a22d61e7164afd2b 149 SUPERFAMILY SSF55729 9 148 8.54E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Pfam PF01595 Domain of unknown function DUF21 10 188 4.1E-41 T 06-07-2017 IPR002550 Domain of unknown function DUF21 CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Gene3D G3DSA:3.10.580.10 191 322 1.4E-19 T 06-07-2017 CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 SMART SM01091 343 421 4.2E-25 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Pfam PF00571 CBS domain 205 262 2.4E-4 T 06-07-2017 IPR000644 CBS domain CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Pfam PF00571 CBS domain 288 328 2.9E-5 T 06-07-2017 IPR000644 CBS domain CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 SUPERFAMILY SSF56176 343 423 1.25E-21 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Pfam PF03471 Transporter associated domain 345 419 3.2E-19 T 06-07-2017 IPR005170 Transporter-associated domain CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 Gene3D G3DSA:3.30.465.10 323 420 1.6E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 SUPERFAMILY SSF54631 201 344 2.53E-30 T 06-07-2017 CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 SMART SM00116 280 328 8.2 T 06-07-2017 IPR000644 CBS domain CAK95_RS10510 6acc1b490222438824aa0ad61ea25b1f 426 SMART SM00116 214 263 0.049 T 06-07-2017 IPR000644 CBS domain CAK95_RS02890 6f49ba34a2565ca237d66be5b61089b2 338 SUPERFAMILY SSF81345 7 330 1.18E-73 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS02890 6f49ba34a2565ca237d66be5b61089b2 338 Gene3D G3DSA:1.10.3470.10 5 333 1.7E-96 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS02890 6f49ba34a2565ca237d66be5b61089b2 338 Pfam PF01032 FecCD transport family 17 331 1.1E-83 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 SUPERFAMILY SSF48498 79 186 1.53E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 SUPERFAMILY SSF46689 2 79 5.99E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14005 a0d013e6b436c06baa0e98601a6c0dc2 229 Gene3D G3DSA:1.10.357.10 7 187 2.0E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 Pfam PF13242 HAD-hyrolase-like 193 265 1.8E-11 T 06-07-2017 CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 18 248 4.6E-36 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 SUPERFAMILY SSF56784 15 263 5.97E-45 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 9 246 4.3E-48 T 06-07-2017 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 Pfam PF13344 Haloacid dehalogenase-like hydrolase 18 114 3.0E-13 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 Gene3D G3DSA:3.40.50.1000 14 87 9.4E-27 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS13285 9357f5d1d7d77c5ca6b4b2950469e5ab 285 Gene3D G3DSA:3.40.50.1000 193 263 9.4E-27 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS10870 422f93521b34d57b4a96a549d103f2e1 266 Gene3D G3DSA:3.40.50.300 3 237 1.3E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10870 422f93521b34d57b4a96a549d103f2e1 266 SMART SM00382 29 228 3.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10870 422f93521b34d57b4a96a549d103f2e1 266 SUPERFAMILY SSF52540 4 233 2.5E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10870 422f93521b34d57b4a96a549d103f2e1 266 Pfam PF00005 ABC transporter 20 172 6.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS18245 16ead5533f3fbe5cba34cd7e338b982b 392 Pfam PF03929 PepSY-associated TM region 12 362 3.2E-54 T 06-07-2017 IPR005625 PepSY-associated TM protein CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 41 74 2.5E-6 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 Gene3D G3DSA:3.10.20.30 6 85 6.3E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 Gene3D G3DSA:1.10.150.120 86 173 1.3E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 Pfam PF01799 [2Fe-2S] binding domain 84 168 3.1E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 SUPERFAMILY SSF54292 9 89 6.16E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS27985 c792dbc2e38302cdc0545c8a4f8ac596 181 SUPERFAMILY SSF47741 101 173 4.45E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS07070 2e22e22c5fac4e9dc1c5d7b2545cdf89 96 SMART SM00418 8 93 2.0E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS07070 2e22e22c5fac4e9dc1c5d7b2545cdf89 96 SUPERFAMILY SSF46785 1 91 9.25E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07070 2e22e22c5fac4e9dc1c5d7b2545cdf89 96 Gene3D G3DSA:1.10.10.10 1 94 2.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07070 2e22e22c5fac4e9dc1c5d7b2545cdf89 96 Pfam PF12840 Helix-turn-helix domain 7 73 2.2E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07705 836ca29544bb9891b2345806a6896506 200 SUPERFAMILY SSF53335 9 170 9.91E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS07705 836ca29544bb9891b2345806a6896506 200 Gene3D G3DSA:3.40.50.150 29 119 2.5E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15360 61ad19d291167e789116786d0df890f7 91 Gene3D G3DSA:1.10.10.10 10 91 5.9E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15360 61ad19d291167e789116786d0df890f7 91 Pfam PF06627 Protein of unknown function (DUF1153) 7 90 3.3E-42 T 06-07-2017 IPR009534 Protein of unknown function DUF1153 CAK95_RS15360 61ad19d291167e789116786d0df890f7 91 SUPERFAMILY SSF48295 12 91 2.35E-20 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAK95_RS07765 fd91b4dea10341929f9b97cebe106fe9 111 SUPERFAMILY SSF46626 37 99 4.48E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS04000 18ee31ac06757a83aece4c8f17e605a6 313 SUPERFAMILY SSF74653 113 121 3.73E-9 T 06-07-2017 CAK95_RS04000 18ee31ac06757a83aece4c8f17e605a6 313 SUPERFAMILY SSF74653 205 309 3.73E-9 T 06-07-2017 CAK95_RS04000 18ee31ac06757a83aece4c8f17e605a6 313 Gene3D G3DSA:3.30.1150.10 205 311 1.4E-14 T 06-07-2017 CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 SUPERFAMILY SSF51735 150 319 1.58E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 Gene3D G3DSA:3.40.50.720 179 290 3.3E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 Pfam PF00107 Zinc-binding dehydrogenase 187 305 9.0E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 SUPERFAMILY SSF50129 5 171 1.34E-39 T 06-07-2017 IPR011032 GroES-like CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 SMART SM00829 13 352 8.0E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 139 5.3E-23 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS06495 43b936344d1eb51bd06c94c059733962 358 Gene3D G3DSA:3.90.180.10 2 178 4.0E-40 T 06-07-2017 IPR011032 GroES-like CAK95_RS03360 cd7269f47f0a0e9b1cb7686a89443a2b 342 Pfam PF03601 Conserved hypothetical protein 698 19 319 2.0E-86 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CAK95_RS03055 434a91b15e2dc4dd098b93d3716e5824 174 SUPERFAMILY SSF53098 23 169 7.21E-23 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS03055 434a91b15e2dc4dd098b93d3716e5824 174 Gene3D G3DSA:3.30.420.10 69 164 9.4E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS11935 74b336b0c730b0d961a84e14d270a70a 194 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 189 3.9E-57 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK95_RS11935 74b336b0c730b0d961a84e14d270a70a 194 Pfam PF01923 Cobalamin adenosyltransferase 7 177 1.9E-58 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK95_RS11935 74b336b0c730b0d961a84e14d270a70a 194 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 188 5.0E-58 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK95_RS11935 74b336b0c730b0d961a84e14d270a70a 194 Gene3D G3DSA:1.20.1200.10 16 192 1.4E-61 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK95_RS11935 74b336b0c730b0d961a84e14d270a70a 194 SUPERFAMILY SSF89028 6 189 9.22E-58 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK95_RS00530 9d237d26b02953e2bec04e460f7c2b46 260 Gene3D G3DSA:3.40.50.300 3 100 1.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00530 9d237d26b02953e2bec04e460f7c2b46 260 SUPERFAMILY SSF52540 4 181 1.91E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 SUPERFAMILY SSF53474 23 271 7.16E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 Gene3D G3DSA:3.40.50.1820 25 271 1.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01100 ec880f5bf175755407b5a932ca5aa2dc 289 Pfam PF00561 alpha/beta hydrolase fold 27 180 4.8E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS26115 ceb31821a3b69595c519581a177c4175 428 Gene3D G3DSA:2.70.70.10 268 363 9.6E-24 T 06-07-2017 CAK95_RS26115 ceb31821a3b69595c519581a177c4175 428 SUPERFAMILY SSF51261 267 363 7.32E-20 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS26115 ceb31821a3b69595c519581a177c4175 428 Pfam PF01551 Peptidase family M23 268 362 4.8E-17 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS17695 c92d2be6380a7f2ecafd5688ec1a497b 335 Pfam PF13489 Methyltransferase domain 124 274 1.9E-17 T 06-07-2017 CAK95_RS17695 c92d2be6380a7f2ecafd5688ec1a497b 335 SUPERFAMILY SSF53335 120 308 9.87E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17695 c92d2be6380a7f2ecafd5688ec1a497b 335 Gene3D G3DSA:3.40.50.150 117 306 5.6E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06365 ea3725c7f07e0d0967e03f296f780b64 257 Pfam PF01925 Sulfite exporter TauE/SafE 10 249 1.8E-35 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 SUPERFAMILY SSF47384 244 325 1.61E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 482 5.3E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 324 1.1E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 SMART SM00387 370 483 3.1E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 SUPERFAMILY SSF55874 313 480 1.31E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 Gene3D G3DSA:3.30.565.10 311 480 2.4E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 SMART SM00388 255 324 9.6E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS19800 a4e9f32b864652cd8f73adea39439947 523 Gene3D G3DSA:1.10.287.130 248 310 5.3E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 SUPERFAMILY SSF52540 4 247 1.01E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 6 256 5.3E-82 T 06-07-2017 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 Pfam PF00005 ABC transporter 22 187 1.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 Gene3D G3DSA:3.40.50.300 2 249 2.0E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27935 9a8c63ce6fd0bad70ad265ec41fba37e 309 SMART SM00382 31 244 9.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21905 3754d0c7ef58dc420adb69fce767a2b6 334 TIGRFAM TIGR03814 Gln_ase: glutaminase A 41 328 2.1E-99 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS21905 3754d0c7ef58dc420adb69fce767a2b6 334 Gene3D G3DSA:3.40.710.10 25 328 2.1E-103 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS21905 3754d0c7ef58dc420adb69fce767a2b6 334 Pfam PF04960 Glutaminase 44 328 1.8E-96 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS21905 3754d0c7ef58dc420adb69fce767a2b6 334 SUPERFAMILY SSF56601 26 328 8.7E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS21905 3754d0c7ef58dc420adb69fce767a2b6 334 Hamap MF_00313 Glutaminase [glsA]. 26 328 40.143 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CAK95_RS26080 b3a73882bb96a57408f1f935e432f82e 71 SUPERFAMILY SSF51621 29 71 3.98E-7 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26080 b3a73882bb96a57408f1f935e432f82e 71 Gene3D G3DSA:3.20.20.60 32 71 1.4E-9 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26080 b3a73882bb96a57408f1f935e432f82e 71 Pfam PF02548 Ketopantoate hydroxymethyltransferase 33 71 1.8E-9 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK95_RS11265 6c32e1f41fe8fe92b294dea0406d120f 365 Pfam PF12849 PBP superfamily domain 35 330 4.9E-48 T 06-07-2017 IPR024370 PBP domain CAK95_RS11265 6c32e1f41fe8fe92b294dea0406d120f 365 Gene3D G3DSA:3.40.190.10 126 303 5.4E-60 T 06-07-2017 CAK95_RS11265 6c32e1f41fe8fe92b294dea0406d120f 365 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 36 358 4.6E-92 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAK95_RS11265 6c32e1f41fe8fe92b294dea0406d120f 365 SUPERFAMILY SSF53850 36 359 4.16E-81 T 06-07-2017 CAK95_RS07670 ee7cda594781da829cd83c392a5eea0f 136 Pfam PF03625 Domain of unknown function DUF302 41 101 1.6E-17 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAK95_RS07670 ee7cda594781da829cd83c392a5eea0f 136 SUPERFAMILY SSF103247 10 132 1.44E-30 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAK95_RS07670 ee7cda594781da829cd83c392a5eea0f 136 Gene3D G3DSA:3.30.310.70 10 132 1.2E-29 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 SUPERFAMILY SSF46785 2 71 5.99E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 Gene3D G3DSA:1.10.10.10 2 69 1.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 SMART SM00346 1 90 0.0059 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 Pfam PF01614 Bacterial transcriptional regulator 125 245 9.7E-19 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 Gene3D G3DSA:3.30.450.40 70 242 5.4E-35 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS00695 e1a5342caeb4c1aeb52fa5ea4e0fcc52 271 SUPERFAMILY SSF55781 58 246 9.81E-33 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 Gene3D G3DSA:1.10.357.10 75 178 5.4E-5 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 Gene3D G3DSA:1.10.10.60 5 40 6.0E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 Gene3D G3DSA:1.10.10.60 41 74 2.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 SUPERFAMILY SSF46689 3 80 3.03E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 SUPERFAMILY SSF48498 75 182 3.17E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 8.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS08400 69e7d613c5db2c887f3ea3ef3dcf8ccf 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 8.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS16245 94dc2ce234829f15c96753661dd5ac63 265 SUPERFAMILY SSF53474 22 263 4.94E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16245 94dc2ce234829f15c96753661dd5ac63 265 Pfam PF12146 Serine aminopeptidase, S33 72 174 1.5E-11 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK95_RS16245 94dc2ce234829f15c96753661dd5ac63 265 Gene3D G3DSA:3.40.50.1820 49 263 3.0E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23160 6ba30c0fa2171caed510c99db59a56ae 105 Pfam PF04977 Septum formation initiator 23 103 3.8E-15 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 SUPERFAMILY SSF52518 343 523 4.98E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 ProSitePatterns PS00802 Transketolase signature 2. 463 479 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 655 6.1E-244 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Gene3D G3DSA:3.40.50.970 3 313 1.7E-120 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 329 2.6E-136 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Gene3D G3DSA:3.40.50.970 323 525 3.8E-79 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Pfam PF02779 Transketolase, pyrimidine binding domain 349 520 6.6E-49 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 SMART SM00861 350 521 1.4E-71 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 SUPERFAMILY SSF52922 530 659 3.8E-34 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Gene3D G3DSA:3.40.50.920 535 657 1.4E-34 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 SUPERFAMILY SSF52518 4 314 6.85E-110 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS04140 1511cebd23aa17a831782b9706ac18f7 661 Pfam PF02780 Transketolase, C-terminal domain 545 651 1.1E-11 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK95_RS26855 b255a151700cb9dc29f9f0ea6d6813d9 297 Pfam PF00483 Nucleotidyl transferase 4 239 8.1E-69 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK95_RS26855 b255a151700cb9dc29f9f0ea6d6813d9 297 Gene3D G3DSA:3.90.550.10 4 262 3.0E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26855 b255a151700cb9dc29f9f0ea6d6813d9 297 SUPERFAMILY SSF53448 4 288 1.91E-88 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26855 b255a151700cb9dc29f9f0ea6d6813d9 297 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 4 288 6.1E-144 T 06-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAK95_RS20440 28e78a9bedf6b00a8a29271b22669d52 244 Pfam PF17036 Cellulose biosynthesis protein BcsS 98 238 5.3E-42 T 06-07-2017 IPR031485 Cellulose biosynthesis protein BcsS CAK95_RS17425 99afb974e81a7015a7352d4f6ae069f2 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 293 1.0E-48 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS23445 1153dec15fa68302a428f0d2413b8b6c 206 SUPERFAMILY SSF46626 1 21 1.29E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23445 1153dec15fa68302a428f0d2413b8b6c 206 SUPERFAMILY SSF46626 89 198 1.29E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23445 1153dec15fa68302a428f0d2413b8b6c 206 PIRSF PIRSF024608 2 205 8.8E-65 T 06-07-2017 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II CAK95_RS23445 1153dec15fa68302a428f0d2413b8b6c 206 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 119 199 5.3E-27 T 06-07-2017 IPR030999 Sulfur oxidation c-type cytochrome SoxX CAK95_RS23445 1153dec15fa68302a428f0d2413b8b6c 206 Gene3D G3DSA:1.10.760.10 89 198 4.6E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 Pfam PF00460 Flagella basal body rod protein 7 35 6.9E-11 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 SUPERFAMILY SSF117143 84 204 9.81E-25 T 06-07-2017 CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 171 240 4.7E-11 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 127 6.8E-44 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAK95_RS18210 9864dc6422d13d80e32392e38182a4a4 248 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 7 222 7.2E-63 T 06-07-2017 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CAK95_RS02415 c309bca710cea0e600d568f4767a12e2 479 Gene3D G3DSA:1.20.1600.10 73 458 2.2E-31 T 06-07-2017 CAK95_RS02415 c309bca710cea0e600d568f4767a12e2 479 SUPERFAMILY SSF56954 6 27 1.96E-57 T 06-07-2017 CAK95_RS02415 c309bca710cea0e600d568f4767a12e2 479 SUPERFAMILY SSF56954 61 458 1.96E-57 T 06-07-2017 CAK95_RS02415 c309bca710cea0e600d568f4767a12e2 479 Pfam PF02321 Outer membrane efflux protein 77 249 8.9E-7 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS02415 c309bca710cea0e600d568f4767a12e2 479 Pfam PF02321 Outer membrane efflux protein 279 453 9.6E-13 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 PIRSF PIRSF000090 1 249 3.5E-86 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 Pfam PF01012 Electron transfer flavoprotein domain 29 204 3.9E-47 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 Gene3D G3DSA:3.40.50.620 1 246 2.1E-104 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 SMART SM00893 23 211 5.5E-70 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 06-07-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 CAK95_RS11940 f7219b34e33ce2196826e3d48b3c2f69 249 SUPERFAMILY SSF52402 1 242 1.81E-85 T 06-07-2017 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 Pfam PF03466 LysR substrate binding domain 87 287 2.7E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 Gene3D G3DSA:1.10.10.10 1 87 3.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-24 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 Gene3D G3DSA:3.40.190.10 88 176 5.1E-23 T 06-07-2017 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 SUPERFAMILY SSF46785 1 111 5.38E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 Gene3D G3DSA:3.40.190.10 177 259 2.7E-17 T 06-07-2017 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05790 f08112eaebe6b7dd70f48108733cd8d8 291 SUPERFAMILY SSF53850 88 290 3.06E-40 T 06-07-2017 CAK95_RS18355 89a4a55a0b1a8f762cafdcd26364c81c 331 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 105 319 1.7E-40 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS18355 89a4a55a0b1a8f762cafdcd26364c81c 331 Gene3D G3DSA:3.90.850.10 76 320 1.8E-53 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS18355 89a4a55a0b1a8f762cafdcd26364c81c 331 SUPERFAMILY SSF56529 78 320 7.72E-45 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS11145 23d05ec2bc216afe3a9fd0b12e24e1f4 336 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK95_RS11145 23d05ec2bc216afe3a9fd0b12e24e1f4 336 Gene3D G3DSA:1.10.600.10 15 334 5.6E-96 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS11145 23d05ec2bc216afe3a9fd0b12e24e1f4 336 Pfam PF00348 Polyprenyl synthetase 44 288 9.9E-69 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK95_RS11145 23d05ec2bc216afe3a9fd0b12e24e1f4 336 SUPERFAMILY SSF48576 14 335 2.72E-94 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 SUPERFAMILY SSF52518 428 612 1.02E-8 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 Gene3D G3DSA:3.40.50.970 487 647 6.8E-9 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 721 907 7.1E-21 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 SUPERFAMILY SSF53323 713 962 9.55E-24 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 SUPERFAMILY SSF52922 262 366 5.16E-6 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 Gene3D G3DSA:3.40.920.10 714 907 2.6E-13 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS11770 ae7bb33a1ac926777138a06165262f43 1140 SUPERFAMILY SSF52518 16 198 8.24E-16 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS17145 83608ab1c29642296400a87aa8e03f99 332 Pfam PF09084 NMT1/THI5 like 52 255 5.6E-15 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS17145 83608ab1c29642296400a87aa8e03f99 332 Gene3D G3DSA:3.40.190.10 120 241 8.7E-16 T 06-07-2017 CAK95_RS17145 83608ab1c29642296400a87aa8e03f99 332 SUPERFAMILY SSF53850 37 257 3.2E-30 T 06-07-2017 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 147 1.1E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 Pfam PF00593 TonB dependent receptor 471 741 3.4E-16 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 SUPERFAMILY SSF56935 25 499 2.86E-78 T 06-07-2017 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 SUPERFAMILY SSF56935 535 744 2.86E-78 T 06-07-2017 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 Gene3D G3DSA:2.40.170.20 150 743 9.3E-52 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS15300 10e7855c96090e1c010f578f8700add5 744 Gene3D G3DSA:2.170.130.10 24 149 4.4E-26 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS14790 b6cab204b6837fd9e24c2202737890f3 233 Gene3D G3DSA:3.90.79.10 97 192 1.3E-5 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS14790 b6cab204b6837fd9e24c2202737890f3 233 SUPERFAMILY SSF55811 100 210 1.27E-7 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.4E-24 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 SUPERFAMILY SSF50249 2 65 7.5E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 Gene3D G3DSA:2.40.50.140 2 66 3.3E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 PRINTS PR00050 Cold shock protein signature 4 19 1.0E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 PRINTS PR00050 Cold shock protein signature 40 58 1.0E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 PRINTS PR00050 Cold shock protein signature 25 34 1.0E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 PIRSF PIRSF002599 1 67 3.4E-22 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK95_RS07270 7f75e5313c648b6d3d171d6d4323bd77 67 SMART SM00357 3 67 3.4E-26 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 SUPERFAMILY SSF56645 35 280 1.7E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Gene3D G3DSA:2.40.110.10 160 268 1.0E-27 T 06-07-2017 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 156 1.1E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 467 586 4.4E-19 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 SUPERFAMILY SSF47203 288 471 3.38E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 450 5.5E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Gene3D G3DSA:1.20.140.10 269 459 1.0E-54 T 06-07-2017 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Gene3D G3DSA:1.10.540.10 39 157 3.1E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS00160 3d7a8c43a91765b78f719d535b429261 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 270 2.5E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS00795 96c9b3769d8a90e465990a9771450a3e 478 SUPERFAMILY SSF143968 309 442 5.75E-39 T 06-07-2017 CAK95_RS00795 96c9b3769d8a90e465990a9771450a3e 478 SUPERFAMILY SSF50475 19 306 3.33E-82 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS00795 96c9b3769d8a90e465990a9771450a3e 478 Gene3D G3DSA:3.40.1670.10 323 435 1.9E-34 T 06-07-2017 CAK95_RS00795 96c9b3769d8a90e465990a9771450a3e 478 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 21 436 9.5E-106 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS00795 96c9b3769d8a90e465990a9771450a3e 478 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 27 412 4.8E-109 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS14190 1389593eaf0f40f506854f34a0f3aef8 287 Gene3D G3DSA:3.40.50.1820 15 270 1.0E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14190 1389593eaf0f40f506854f34a0f3aef8 287 Pfam PF12697 Alpha/beta hydrolase family 34 261 4.8E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS14190 1389593eaf0f40f506854f34a0f3aef8 287 SUPERFAMILY SSF53474 15 270 4.19E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 Gene3D G3DSA:1.10.1370.10 515 689 1.8E-116 T 06-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 Gene3D G3DSA:1.10.1370.10 156 362 1.8E-116 T 06-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 Gene3D G3DSA:1.20.1050.40 23 155 4.9E-19 T 06-07-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 Gene3D G3DSA:3.40.390.10 372 514 1.8E-51 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 Pfam PF01432 Peptidase family M3 239 688 3.7E-123 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 CAK95_RS12950 fd0689783fd428a6c357e3d59f1f6b4c 698 SUPERFAMILY SSF55486 22 688 1.34E-188 T 06-07-2017 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 Gene3D G3DSA:1.10.260.40 14 67 1.0E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 Gene3D G3DSA:3.40.50.2300 68 185 7.6E-44 T 06-07-2017 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 Gene3D G3DSA:3.40.50.2300 186 324 1.0E-40 T 06-07-2017 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 SMART SM00354 13 85 7.3E-19 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 Pfam PF00356 Bacterial regulatory proteins, lacI family 16 62 1.1E-8 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 SUPERFAMILY SSF53822 74 345 1.22E-72 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 SUPERFAMILY SSF47413 13 73 2.72E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS12690 1956db1949301ca9779486bad03d8ad0 361 Pfam PF13377 Periplasmic binding protein-like domain 182 343 7.6E-32 T 06-07-2017 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 Pfam PF03466 LysR substrate binding domain 94 298 1.5E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 SUPERFAMILY SSF46785 3 86 2.93E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 SUPERFAMILY SSF53850 94 301 1.81E-24 T 06-07-2017 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 Gene3D G3DSA:3.40.190.10 177 265 6.9E-8 T 06-07-2017 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 Gene3D G3DSA:1.10.10.10 6 89 7.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 TIGRFAM TIGR02424 TF_pcaQ: pca operon transcription factor PcaQ 5 299 1.3E-92 T 06-07-2017 IPR012787 Pca transcription factor PcaQ GO:0003677|GO:0019619|GO:0045893 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 6.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05285 d3eaa194c3adfc0bb35c0dc2e46f5839 306 Gene3D G3DSA:3.40.190.10 94 176 3.8E-11 T 06-07-2017 CAK95_RS03780 1eac9b8af6c3d8b2542b91080830c35e 282 SUPERFAMILY SSF52540 27 250 9.35E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03780 1eac9b8af6c3d8b2542b91080830c35e 282 Pfam PF00005 ABC transporter 48 183 7.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS03780 1eac9b8af6c3d8b2542b91080830c35e 282 Gene3D G3DSA:3.40.50.300 18 239 1.0E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03780 1eac9b8af6c3d8b2542b91080830c35e 282 SMART SM00382 56 233 2.0E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS03780 1eac9b8af6c3d8b2542b91080830c35e 282 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS15825 9a68ccfbc3e3929a64e855aba09654c9 308 SUPERFAMILY SSF56300 75 307 2.36E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS15825 9a68ccfbc3e3929a64e855aba09654c9 308 Pfam PF00149 Calcineurin-like phosphoesterase 72 246 6.5E-10 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS15825 9a68ccfbc3e3929a64e855aba09654c9 308 Gene3D G3DSA:3.60.21.10 73 253 5.6E-21 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 Pfam PF02033 Ribosome-binding factor A 17 122 1.9E-27 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 20 109 5.0E-36 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 13 129 19.411 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 ProSitePatterns PS01319 Ribosome-binding factor A signature. 88 109 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 Gene3D G3DSA:3.30.300.20 15 129 1.5E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 15 123 1.2E-17 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK95_RS09160 4dd1f53e345cbaf1f40bf4b3f44c7004 138 SUPERFAMILY SSF89919 14 124 1.1E-30 T 06-07-2017 IPR023799 Ribosome-binding factor A domain CAK95_RS04970 5721beb1eae928f7e24ac9be6e7761d9 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 136 1.7E-27 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS04970 5721beb1eae928f7e24ac9be6e7761d9 141 Gene3D G3DSA:3.10.129.10 10 137 4.7E-31 T 06-07-2017 IPR029069 HotDog domain CAK95_RS04970 5721beb1eae928f7e24ac9be6e7761d9 141 SUPERFAMILY SSF54637 14 138 1.01E-28 T 06-07-2017 IPR029069 HotDog domain CAK95_RS04970 5721beb1eae928f7e24ac9be6e7761d9 141 Pfam PF03061 Thioesterase superfamily 55 128 2.1E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PIRSF PIRSF004557 9 441 1.2E-118 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 273 292 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 181 204 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 155 180 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 120 143 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 8.8E-97 T 06-07-2017 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 Pfam PF00344 SecY translocase 81 417 1.4E-116 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 433 29.793 T 06-07-2017 IPR026593 Protein translocase subunit SecY CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 SUPERFAMILY SSF103491 18 424 2.62E-129 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 24 428 1.0E-127 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 Gene3D G3DSA:1.10.3370.10 19 437 9.2E-164 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS21365 6377f1b3900d51b930ea09cb8e99e2c9 443 ProSitePatterns PS00756 Protein secY signature 2. 174 191 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK95_RS13915 abd2fc9b610a69466dd5a5f1bf97aab9 218 Gene3D G3DSA:3.40.50.850 13 204 3.9E-37 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS13915 abd2fc9b610a69466dd5a5f1bf97aab9 218 SUPERFAMILY SSF52499 12 206 1.24E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS13915 abd2fc9b610a69466dd5a5f1bf97aab9 218 Pfam PF00857 Isochorismatase family 20 169 1.6E-20 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS13935 02f01e164ac5d64c54343dabf725aaa8 292 Gene3D G3DSA:3.90.260.10 180 244 2.2E-11 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS13935 02f01e164ac5d64c54343dabf725aaa8 292 Pfam PF01841 Transglutaminase-like superfamily 139 241 1.8E-21 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS13935 02f01e164ac5d64c54343dabf725aaa8 292 SUPERFAMILY SSF54001 7 270 3.14E-40 T 06-07-2017 CAK95_RS13935 02f01e164ac5d64c54343dabf725aaa8 292 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 83 3.0E-22 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAK95_RS13935 02f01e164ac5d64c54343dabf725aaa8 292 SMART SM00460 175 243 8.7E-19 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 SMART SM01080 56 387 5.9E-82 T 06-07-2017 IPR007890 CHASE2 CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 SMART SM00044 451 657 4.4E-14 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 484 672 1.5E-29 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 SUPERFAMILY SSF55073 480 678 1.11E-54 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 Pfam PF05226 CHASE2 domain 43 385 2.3E-59 T 06-07-2017 IPR007890 CHASE2 CAK95_RS09835 eaac10e6c98dbc1dc13d2d673ea475d8 757 Gene3D G3DSA:3.30.70.1230 485 676 4.7E-45 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS08145 280fa925df651d004836d70cd68a6308 232 Gene3D G3DSA:3.40.50.150 35 208 4.2E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08145 280fa925df651d004836d70cd68a6308 232 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 39 197 1.0E-33 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK95_RS08145 280fa925df651d004836d70cd68a6308 232 SUPERFAMILY SSF53335 27 201 2.22E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08145 280fa925df651d004836d70cd68a6308 232 Pfam PF02527 rRNA small subunit methyltransferase G 37 203 6.0E-39 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK95_RS08145 280fa925df651d004836d70cd68a6308 232 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 27 218 24.42 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 Gene3D G3DSA:3.90.1150.10 16 70 3.6E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 Gene3D G3DSA:3.90.1150.10 350 448 3.6E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 Gene3D G3DSA:3.40.640.10 72 348 1.3E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 Pfam PF00202 Aminotransferase class-III 28 445 1.6E-104 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS13265 2ffa734c985cf4c55e3f57c58748ee09 449 SUPERFAMILY SSF53383 17 446 1.37E-114 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS12170 71417445fb8d75096c1bd43b7ad90a5a 173 SUPERFAMILY SSF54001 63 161 2.6E-9 T 06-07-2017 CAK95_RS12170 71417445fb8d75096c1bd43b7ad90a5a 173 TIGRFAM TIGR02594 TIGR02594: TIGR02594 family protein 81 172 7.5E-34 T 06-07-2017 IPR013423 Conserved hypothetical protein CHP02594 CAK95_RS12170 71417445fb8d75096c1bd43b7ad90a5a 173 Pfam PF05257 CHAP domain 77 152 1.4E-8 T 06-07-2017 IPR007921 CHAP domain CAK95_RS12170 71417445fb8d75096c1bd43b7ad90a5a 173 Gene3D G3DSA:3.90.1720.10 61 165 7.9E-6 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 223 243 8.0E-9 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 290 308 8.0E-9 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 244 262 8.0E-9 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 Hamap MF_00900 GTPase HflX [hflX]. 49 420 47.7 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 Pfam PF13167 GTP-binding GTPase N-terminal 47 133 6.0E-28 T 06-07-2017 IPR025121 GTPase HflX, N-terminal CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 PIRSF PIRSF006809 16 453 2.5E-147 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 Gene3D G3DSA:3.40.50.300 221 393 1.0E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 Pfam PF16360 GTP-binding GTPase Middle Region 136 215 5.4E-30 T 06-07-2017 IPR032305 GTP-binding protein, middle domain CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 Pfam PF01926 50S ribosome-binding GTPase 223 344 2.3E-19 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 SUPERFAMILY SSF52540 221 404 2.5E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23280 5b1619edf2dbc6fb3844fbf43aa91eb8 455 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 41 391 7.6E-139 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK95_RS25600 07f24bc29e76602129bd4c01fb229dcd 87 Pfam PF12071 Protein of unknown function (DUF3551) 1 69 5.5E-10 T 06-07-2017 IPR021937 Protein of unknown function DUF3551 CAK95_RS23140 7799851ba6d36888017b17bc9573c307 279 Pfam PF00793 DAHP synthetase I family 17 268 6.3E-72 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAK95_RS23140 7799851ba6d36888017b17bc9573c307 279 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 24 278 9.4E-123 T 06-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAK95_RS23140 7799851ba6d36888017b17bc9573c307 279 SUPERFAMILY SSF51569 9 278 1.19E-106 T 06-07-2017 CAK95_RS23140 7799851ba6d36888017b17bc9573c307 279 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 18 279 52.254 T 06-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAK95_RS23140 7799851ba6d36888017b17bc9573c307 279 Gene3D G3DSA:3.20.20.70 23 278 2.3E-111 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 Gene3D G3DSA:1.10.357.10 69 211 1.6E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 2.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 Gene3D G3DSA:1.10.10.60 22 68 1.8E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 162 211 6.6E-8 T 06-07-2017 CAK95_RS27360 979c505767046f225cabe4fcde619699 212 SUPERFAMILY SSF46689 18 91 1.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS10520 3f80e7a2156d5f9ad8e7a686117a63d5 90 Pfam PF01722 BolA-like protein 11 88 4.1E-31 T 06-07-2017 IPR002634 BolA protein CAK95_RS10520 3f80e7a2156d5f9ad8e7a686117a63d5 90 SUPERFAMILY SSF82657 2 88 4.71E-27 T 06-07-2017 IPR002634 BolA protein CAK95_RS10520 3f80e7a2156d5f9ad8e7a686117a63d5 90 PIRSF PIRSF003113 1 90 7.0E-30 T 06-07-2017 IPR002634 BolA protein CAK95_RS10520 3f80e7a2156d5f9ad8e7a686117a63d5 90 Gene3D G3DSA:3.30.70.1500 2 83 9.1E-30 T 06-07-2017 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 SUPERFAMILY SSF46626 44 173 1.31E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 Gene3D G3DSA:1.10.760.10 309 417 9.2E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 SUPERFAMILY SSF46626 328 427 1.45E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 PIRSF PIRSF000018 18 427 3.9E-129 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 323 407 1.6E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 Gene3D G3DSA:1.10.760.10 194 298 3.0E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 Gene3D G3DSA:1.10.760.10 49 150 3.0E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 Pfam PF00034 Cytochrome c 53 151 1.6E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS27980 63dbab84cb2566633d5005a87d663dfc 427 SUPERFAMILY SSF46626 197 302 1.11E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 Gene3D G3DSA:1.10.530.10 612 753 2.8E-42 T 06-07-2017 CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 621 649 - T 06-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 SUPERFAMILY SSF53955 613 754 5.94E-44 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 Gene3D G3DSA:1.25.20.10 149 509 2.0E-29 T 06-07-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 SUPERFAMILY SSF48435 150 577 3.53E-62 T 06-07-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 CAK95_RS23740 f00cfbfe270ad8de3877debcf4fcc621 770 Pfam PF01464 Transglycosylase SLT domain 611 714 6.6E-27 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 Pfam PF00732 GMC oxidoreductase 6 296 1.8E-82 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 SUPERFAMILY SSF51905 476 536 8.88E-91 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 SUPERFAMILY SSF51905 2 289 8.88E-91 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 SUPERFAMILY SSF54373 291 477 1.37E-41 T 06-07-2017 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 Gene3D G3DSA:3.50.50.60 470 536 3.9E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 Gene3D G3DSA:3.50.50.60 188 314 3.9E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 Gene3D G3DSA:3.50.50.60 3 127 3.9E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 PIRSF PIRSF000137 1 537 5.5E-148 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK95_RS27190 afd506e7c8e34730fb0e0f9d972ec93d 537 Pfam PF05199 GMC oxidoreductase 391 529 5.8E-41 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Gene3D G3DSA:3.30.300.30 403 503 1.9E-25 T 06-07-2017 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 492 2.8E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Pfam PF00501 AMP-binding enzyme 22 408 7.0E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Gene3D G3DSA:2.30.38.10 325 402 2.4E-19 T 06-07-2017 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Gene3D G3DSA:3.40.50.980 21 168 7.9E-22 T 06-07-2017 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 SUPERFAMILY SSF56801 14 504 1.18E-118 T 06-07-2017 CAK95_RS00105 e4983d576d2151d9d4cbab0ab302bd8c 507 Gene3D G3DSA:3.40.50.980 169 324 8.4E-35 T 06-07-2017 CAK95_RS18660 63574b84e10df48948cafb5273d4db21 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 3.1E-39 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS10560 d82128a251cce2cd5bce2c0074532a99 123 Gene3D G3DSA:3.10.290.10 2 86 1.3E-23 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS10560 d82128a251cce2cd5bce2c0074532a99 123 SMART SM00363 4 69 9.8E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS10560 d82128a251cce2cd5bce2c0074532a99 123 Pfam PF01479 S4 domain 4 51 5.2E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK95_RS10560 d82128a251cce2cd5bce2c0074532a99 123 SUPERFAMILY SSF55174 3 84 7.54E-21 T 06-07-2017 CAK95_RS25595 b599173bad3fa02acf38f87e4dbe2e64 170 PIRSF PIRSF003174 1 164 9.0E-69 T 06-07-2017 IPR010292 Uncharacterised protein family CreA CAK95_RS25595 b599173bad3fa02acf38f87e4dbe2e64 170 Pfam PF05981 CreA protein 28 155 7.7E-51 T 06-07-2017 IPR010292 Uncharacterised protein family CreA CAK95_RS12365 9446ccee030cd53fcf4355a8dea460f1 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 286 3.3E-44 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS08395 ae39416c3d9a9544d515a3b8c9238a0d 526 Gene3D G3DSA:3.40.605.10 8 268 8.3E-35 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS08395 ae39416c3d9a9544d515a3b8c9238a0d 526 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 8 519 4.7E-171 T 06-07-2017 IPR011966 Phenylacetic acid degradation protein PaaN CAK95_RS08395 ae39416c3d9a9544d515a3b8c9238a0d 526 SUPERFAMILY SSF53720 5 505 2.88E-77 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS08395 ae39416c3d9a9544d515a3b8c9238a0d 526 Gene3D G3DSA:3.40.309.10 269 446 8.4E-36 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS08395 ae39416c3d9a9544d515a3b8c9238a0d 526 Pfam PF00171 Aldehyde dehydrogenase family 16 504 5.5E-63 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS20365 0fa6af1fad839abf0207f2968d2b151c 320 SUPERFAMILY SSF53850 109 280 1.54E-10 T 06-07-2017 CAK95_RS20365 0fa6af1fad839abf0207f2968d2b151c 320 PIRSF PIRSF017082 1 319 3.1E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20365 0fa6af1fad839abf0207f2968d2b151c 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 4.4E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 6.2E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 Pfam PF00072 Response regulator receiver domain 4 113 1.7E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 SUPERFAMILY SSF52172 1 175 3.7E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 Gene3D G3DSA:3.40.50.2300 1 123 2.2E-37 T 06-07-2017 CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 Gene3D G3DSA:1.10.10.10 133 232 4.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 SMART SM00448 2 112 2.8E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06840 da30d84ea0134df4af711817e5dc95bf 233 SMART SM00862 154 230 1.1E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS00355 40f23ae007678c086fd45a4237666299 122 SUPERFAMILY SSF54909 33 103 5.09E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS00355 40f23ae007678c086fd45a4237666299 122 Gene3D G3DSA:3.30.70.1060 35 102 2.3E-11 T 06-07-2017 CAK95_RS00355 40f23ae007678c086fd45a4237666299 122 Pfam PF03795 YCII-related domain 34 93 2.0E-8 T 06-07-2017 IPR005545 YCII-related CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 1.8E-23 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.8E-23 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.8E-23 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.8E-23 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 248 7.2E-59 T 06-07-2017 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CAK95_RS18295 28fb5ed1cb96cc4389ec1b8915807b52 256 Pfam PF01311 Bacterial export proteins, family 1 13 245 4.7E-61 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAK95_RS05495 a74a01141535f9a0658c216cbac3c5bd 284 Gene3D G3DSA:1.20.120.80 75 273 4.8E-73 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05495 a74a01141535f9a0658c216cbac3c5bd 284 SUPERFAMILY SSF81452 5 272 3.87E-99 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05495 a74a01141535f9a0658c216cbac3c5bd 284 Pfam PF00510 Cytochrome c oxidase subunit III 8 273 5.0E-95 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05495 a74a01141535f9a0658c216cbac3c5bd 284 Gene3D G3DSA:1.10.287.70 5 73 1.7E-29 T 06-07-2017 CAK95_RS07415 a3c5489517913745a68d0329f827364b 319 Pfam PF04199 Putative cyclase 70 254 5.5E-27 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS07415 a3c5489517913745a68d0329f827364b 319 SUPERFAMILY SSF102198 67 318 3.01E-32 T 06-07-2017 CAK95_RS07415 a3c5489517913745a68d0329f827364b 319 Gene3D G3DSA:3.50.30.50 67 318 6.7E-40 T 06-07-2017 CAK95_RS00075 21759d6ae335c2d04c061a72d397cb1c 282 Gene3D G3DSA:2.60.120.10 182 262 2.3E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS00075 21759d6ae335c2d04c061a72d397cb1c 282 SUPERFAMILY SSF51182 167 261 1.97E-9 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS09920 3128fcd4fa8fa8430bcd78d25447b800 279 Pfam PF00378 Enoyl-CoA hydratase/isomerase 28 278 7.6E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS09920 3128fcd4fa8fa8430bcd78d25447b800 279 Gene3D G3DSA:1.10.12.10 221 279 6.4E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS09920 3128fcd4fa8fa8430bcd78d25447b800 279 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 119 139 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS09920 3128fcd4fa8fa8430bcd78d25447b800 279 SUPERFAMILY SSF52096 12 278 1.69E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS09920 3128fcd4fa8fa8430bcd78d25447b800 279 Gene3D G3DSA:3.90.226.10 17 220 4.2E-52 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS01535 f4323459bf2ab5958f2f6116b81f829c 143 Gene3D G3DSA:2.30.30.240 42 102 1.7E-11 T 06-07-2017 CAK95_RS01535 f4323459bf2ab5958f2f6116b81f829c 143 Pfam PF05239 PRC-barrel domain 41 114 1.7E-12 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS01535 f4323459bf2ab5958f2f6116b81f829c 143 SUPERFAMILY SSF50346 40 123 3.34E-14 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS07120 e90cfc3b5abe9c5161e051db7430cf75 156 SUPERFAMILY SSF140804 62 146 1.12E-28 T 06-07-2017 IPR027405 YidB-like CAK95_RS07120 e90cfc3b5abe9c5161e051db7430cf75 156 Pfam PF06078 Bacterial protein of unknown function (DUF937) 35 137 3.5E-14 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS07120 e90cfc3b5abe9c5161e051db7430cf75 156 Gene3D G3DSA:1.10.10.690 2 14 3.7E-31 T 06-07-2017 IPR027405 YidB-like CAK95_RS07120 e90cfc3b5abe9c5161e051db7430cf75 156 Gene3D G3DSA:1.10.10.690 48 146 3.7E-31 T 06-07-2017 IPR027405 YidB-like CAK95_RS27565 126834e0fe8ca2e4bc61de2a83d76772 161 Gene3D G3DSA:3.10.450.50 5 154 1.7E-42 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS27565 126834e0fe8ca2e4bc61de2a83d76772 161 Pfam PF00866 Ring hydroxylating beta subunit 16 149 1.2E-28 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAK95_RS27565 126834e0fe8ca2e4bc61de2a83d76772 161 SUPERFAMILY SSF54427 4 155 2.66E-39 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS09230 d6a87519c88d54a44b5c43c996cd2542 151 SUPERFAMILY SSF46785 16 142 3.46E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09230 d6a87519c88d54a44b5c43c996cd2542 151 Pfam PF01475 Ferric uptake regulator family 22 141 5.7E-41 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAK95_RS09230 d6a87519c88d54a44b5c43c996cd2542 151 Gene3D G3DSA:1.10.10.10 15 92 2.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28010 597a062a09550b91900135669a74a448 257 SMART SM00345 33 92 2.3E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS28010 597a062a09550b91900135669a74a448 257 SUPERFAMILY SSF64288 81 252 1.54E-29 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS28010 597a062a09550b91900135669a74a448 257 SMART SM00866 112 251 1.8E-18 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS28010 597a062a09550b91900135669a74a448 257 Gene3D G3DSA:1.10.10.10 25 88 4.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28010 597a062a09550b91900135669a74a448 257 Pfam PF07702 UTRA domain 119 244 8.8E-25 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK95_RS28010 597a062a09550b91900135669a74a448 257 Gene3D G3DSA:3.40.1410.10 89 245 5.3E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK95_RS28010 597a062a09550b91900135669a74a448 257 SUPERFAMILY SSF46785 23 96 7.88E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28010 597a062a09550b91900135669a74a448 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 92 1.8E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 117 189 1.8E-6 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 Gene3D G3DSA:3.40.50.720 2 121 8.4E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 SUPERFAMILY SSF51735 2 133 1.18E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 Gene3D G3DSA:3.30.360.10 122 255 3.2E-19 T 06-07-2017 CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 Gene3D G3DSA:3.30.360.10 316 369 3.2E-19 T 06-07-2017 CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 105 1.0E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS02255 11406d74d7dc5b371b283530bab0e642 373 SUPERFAMILY SSF55347 113 222 8.94E-13 T 06-07-2017 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 Gene3D G3DSA:1.10.275.10 2 197 1.2E-70 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 8 505 4.5E-205 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 SUPERFAMILY SSF48557 1 501 1.26E-186 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 504 44.748 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 Gene3D G3DSA:1.20.200.10 198 502 1.2E-121 T 06-07-2017 CAK95_RS06100 ae31c7be2715f4f2dbab7ac94466e0f6 512 Pfam PF00221 Aromatic amino acid lyase 12 470 1.5E-180 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 Pfam PF00355 Rieske [2Fe-2S] domain 57 135 2.2E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 SUPERFAMILY SSF55961 181 426 2.75E-37 T 06-07-2017 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 199 221 3.6E-24 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 92 112 3.6E-24 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 161 187 3.6E-24 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 71 86 3.6E-24 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 113 133 3.6E-24 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 211 425 1.6E-15 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 Gene3D G3DSA:2.102.10.10 57 165 2.3E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 Gene3D G3DSA:3.90.380.10 166 426 2.6E-43 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS02105 6524a8c0d0205f93aba3fc8cf9b7257c 427 SUPERFAMILY SSF50022 24 177 9.04E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 Gene3D G3DSA:1.10.10.10 145 199 3.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 Gene3D G3DSA:3.40.50.2300 6 144 6.2E-32 T 06-07-2017 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 SUPERFAMILY SSF52172 5 150 5.98E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 SUPERFAMILY SSF46894 132 199 9.52E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 SMART SM00448 7 120 5.2E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 SMART SM00421 136 193 3.3E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 191 2.2E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS09630 8923a3c5f4396287959a6eeef04bf65b 201 Pfam PF00072 Response regulator receiver domain 10 120 3.8E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 9.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 9.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 9.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 Gene3D G3DSA:3.40.50.2300 6 145 1.4E-35 T 06-07-2017 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 SMART SM00448 6 117 2.3E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 Gene3D G3DSA:1.10.10.10 146 201 3.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 3.0E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 SUPERFAMILY SSF52172 6 155 1.99E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 SUPERFAMILY SSF46894 133 204 3.16E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 Pfam PF00072 Response regulator receiver domain 8 118 3.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS07090 780fb6330327f343a9b1a8b2b1be257f 206 SMART SM00421 141 198 8.7E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS01795 1cfd1bb7ab02f3a4ee035bced6c29259 384 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 18 364 9.5E-107 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CAK95_RS01795 1cfd1bb7ab02f3a4ee035bced6c29259 384 Pfam PF01098 Cell cycle protein 19 365 2.8E-80 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 Gene3D G3DSA:3.90.76.10 74 147 3.7E-14 T 06-07-2017 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 Gene3D G3DSA:3.40.190.10 148 302 9.2E-21 T 06-07-2017 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 SUPERFAMILY SSF53850 23 574 2.35E-98 T 06-07-2017 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 PIRSF PIRSF002741 3 577 2.5E-79 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 485 1.1E-60 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 Gene3D G3DSA:3.10.105.10 303 339 1.2E-39 T 06-07-2017 CAK95_RS06720 62f263f65827667c9f9b2d2729309dff 585 Gene3D G3DSA:3.10.105.10 372 542 1.2E-39 T 06-07-2017 CAK95_RS07295 823afb55cf8d81f45ef483a245a279ad 129 Pfam PF11162 Protein of unknown function (DUF2946) 20 126 6.2E-6 T 06-07-2017 IPR021333 Protein of unknown function DUF2946 CAK95_RS24000 1b865fd2b1ab4ff0f7d9a85d3ed659c7 283 SUPERFAMILY SSF56529 55 282 3.53E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24000 1b865fd2b1ab4ff0f7d9a85d3ed659c7 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 67 282 1.7E-72 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24000 1b865fd2b1ab4ff0f7d9a85d3ed659c7 283 Pfam PF10370 Domain of unknown function (DUF2437) 1 60 6.0E-6 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 CAK95_RS24000 1b865fd2b1ab4ff0f7d9a85d3ed659c7 283 Gene3D G3DSA:3.90.850.10 60 282 4.5E-86 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 Gene3D G3DSA:3.40.190.10 115 249 8.2E-33 T 06-07-2017 CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 Gene3D G3DSA:3.40.190.10 250 320 8.8E-49 T 06-07-2017 CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 Gene3D G3DSA:3.40.190.10 27 108 8.8E-49 T 06-07-2017 CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 SUPERFAMILY SSF53850 27 320 4.27E-72 T 06-07-2017 CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 7 319 4.0E-90 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS00490 43cb298fb6dce58bb81c533cebac1489 322 Pfam PF16868 NMT1-like family 32 319 1.4E-78 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS20970 b1e5222531199d0d290e992b44a5fe23 146 Pfam PF12276 Protein of unknown function (DUF3617) 5 142 2.0E-11 T 06-07-2017 IPR022061 Protein of unknown function DUF3617 CAK95_RS10250 d317bb6f0c3fbeb8cca9322f164530f9 313 Pfam PF02685 Glucokinase 5 307 7.7E-73 T 06-07-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAK95_RS10250 d317bb6f0c3fbeb8cca9322f164530f9 313 SUPERFAMILY SSF53067 4 309 1.92E-45 T 06-07-2017 CAK95_RS10250 d317bb6f0c3fbeb8cca9322f164530f9 313 Gene3D G3DSA:3.40.367.20 98 291 3.3E-54 T 06-07-2017 CAK95_RS06535 9a9c4bfd7f20b9d786f427e1de6a1c8f 475 Gene3D G3DSA:3.40.309.10 262 447 2.7E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS06535 9a9c4bfd7f20b9d786f427e1de6a1c8f 475 Gene3D G3DSA:3.40.605.10 4 261 6.8E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS06535 9a9c4bfd7f20b9d786f427e1de6a1c8f 475 SUPERFAMILY SSF53720 2 474 1.2E-163 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS06535 9a9c4bfd7f20b9d786f427e1de6a1c8f 475 Pfam PF00171 Aldehyde dehydrogenase family 13 471 7.0E-162 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 SUPERFAMILY SSF52540 3 246 7.23E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 SUPERFAMILY SSF50331 243 342 3.97E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 SMART SM00382 27 214 3.6E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 Gene3D G3DSA:3.40.50.300 3 237 1.1E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 240 3.0E-121 T 06-07-2017 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CAK95_RS14710 2a73e49587f8ac3a1b4caa677c581d17 347 Pfam PF00005 ABC transporter 18 164 5.7E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PIRSF PIRSF006648 3 252 1.3E-27 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 1.1E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 21 42 1.1E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 1.1E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 1.1E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 1.1E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK95_RS13705 ceb406813404052cf695fe6a7baa107b 253 Pfam PF01061 ABC-2 type transporter 5 216 5.3E-36 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK95_RS26075 b00bec1f8aa99d82b17d5044826b6929 128 Pfam PF01042 Endoribonuclease L-PSP 16 127 2.3E-31 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS26075 b00bec1f8aa99d82b17d5044826b6929 128 SUPERFAMILY SSF55298 8 128 2.51E-37 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS26075 b00bec1f8aa99d82b17d5044826b6929 128 Gene3D G3DSA:3.30.1330.40 5 127 1.5E-38 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS20680 16f0701eafbe937bae1531811cf37851 339 SUPERFAMILY SSF51726 4 332 4.32E-61 T 06-07-2017 CAK95_RS20680 16f0701eafbe937bae1531811cf37851 339 Gene3D G3DSA:3.20.20.210 2 337 6.6E-78 T 06-07-2017 CAK95_RS20680 16f0701eafbe937bae1531811cf37851 339 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 2 329 1.1E-28 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS20680 16f0701eafbe937bae1531811cf37851 339 PIRSF PIRSF005632 1 339 4.4E-180 T 06-07-2017 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit CAK95_RS09750 78a87f23b0d0683066a609751f945445 121 Gene3D G3DSA:3.10.180.10 1 114 1.2E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS09750 78a87f23b0d0683066a609751f945445 121 SUPERFAMILY SSF54593 7 113 4.43E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS09750 78a87f23b0d0683066a609751f945445 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 111 7.9E-12 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS09060 74032d350f8ed85462d1b14ea064f65e 259 SUPERFAMILY SSF53474 9 258 8.72E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09060 74032d350f8ed85462d1b14ea064f65e 259 Pfam PF12146 Serine aminopeptidase, S33 55 146 9.0E-9 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK95_RS09060 74032d350f8ed85462d1b14ea064f65e 259 Gene3D G3DSA:3.40.50.1820 27 144 1.9E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS09060 74032d350f8ed85462d1b14ea064f65e 259 Gene3D G3DSA:3.40.50.1820 192 258 1.9E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12910 5a2447cea0df4657a0dcb43fc01aefa8 182 Gene3D G3DSA:1.20.58.320 8 82 1.2E-26 T 06-07-2017 CAK95_RS12910 5a2447cea0df4657a0dcb43fc01aefa8 182 Gene3D G3DSA:1.25.40.10 83 181 1.9E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS12910 5a2447cea0df4657a0dcb43fc01aefa8 182 Pfam PF06041 Bacterial protein of unknown function (DUF924) 12 179 5.4E-53 T 06-07-2017 IPR010323 Protein of unknown function DUF924 CAK95_RS12910 5a2447cea0df4657a0dcb43fc01aefa8 182 SUPERFAMILY SSF48452 9 178 6.83E-58 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS03400 29e79e6273a4d70d64455b8323f551e8 136 SUPERFAMILY SSF109709 55 121 4.71E-8 T 06-07-2017 CAK95_RS06270 0b627fd2e0f3f5f317aa48d058206762 263 SMART SM00382 27 206 3.3E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS06270 0b627fd2e0f3f5f317aa48d058206762 263 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS06270 0b627fd2e0f3f5f317aa48d058206762 263 Gene3D G3DSA:3.40.50.300 2 212 3.4E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06270 0b627fd2e0f3f5f317aa48d058206762 263 SUPERFAMILY SSF52540 2 230 6.52E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06270 0b627fd2e0f3f5f317aa48d058206762 263 Pfam PF00005 ABC transporter 18 155 1.9E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS05950 36da1fb88bbaa18ec0632768c449945f 328 SUPERFAMILY SSF53850 16 247 4.15E-35 T 06-07-2017 CAK95_RS05950 36da1fb88bbaa18ec0632768c449945f 328 Pfam PF09084 NMT1/THI5 like 29 238 2.4E-48 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS05950 36da1fb88bbaa18ec0632768c449945f 328 Gene3D G3DSA:3.40.190.10 99 211 2.8E-16 T 06-07-2017 CAK95_RS12640 fad9be9a15e7e1cd913974d2ea337fce 568 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 275 4.2E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12640 fad9be9a15e7e1cd913974d2ea337fce 568 Gene3D G3DSA:1.10.3720.10 306 548 2.0E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12640 fad9be9a15e7e1cd913974d2ea337fce 568 Gene3D G3DSA:1.10.3720.10 22 280 9.1E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12640 fad9be9a15e7e1cd913974d2ea337fce 568 SUPERFAMILY SSF161098 299 554 2.51E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12640 fad9be9a15e7e1cd913974d2ea337fce 568 SUPERFAMILY SSF161098 18 275 7.76E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 Gene3D G3DSA:3.40.50.150 25 253 1.1E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 25 252 1.5E-80 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 36 51 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 SUPERFAMILY SSF53335 17 251 8.44E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 161 175 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 Pfam PF01209 ubiE/COQ5 methyltransferase family 21 252 1.5E-83 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK95_RS11055 96be1549d0a87b3e500b7c76950579bb 254 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 16 253 37.923 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 SUPERFAMILY SSF46785 3 137 1.61E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 9.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 9.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 9.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 Gene3D G3DSA:1.10.10.10 6 136 3.6E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 SMART SM00347 24 124 2.2E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25500 43d41bc5a5dc9d05b9a5daac79a56709 149 Pfam PF01047 MarR family 31 89 6.1E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS13640 70233f07e436ccb46fae019581587a12 655 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 519 539 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CAK95_RS13640 70233f07e436ccb46fae019581587a12 655 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 49 550 1.5E-194 T 06-07-2017 IPR019899 Sodium/solute symporter, VC2705 subfamily CAK95_RS13640 70233f07e436ccb46fae019581587a12 655 Pfam PF00474 Sodium:solute symporter family 74 338 1.1E-41 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK95_RS13640 70233f07e436ccb46fae019581587a12 655 Pfam PF00474 Sodium:solute symporter family 422 537 2.5E-16 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK95_RS00385 cddfc83fdee8209f958eaa2077d19466 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 24 309 3.2E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS25655 2d676b1fc0f4b353904b4ce25638708f 306 PIRSF PIRSF006232 16 299 9.7E-89 T 06-07-2017 IPR012093 Pirin CAK95_RS25655 2d676b1fc0f4b353904b4ce25638708f 306 Gene3D G3DSA:2.60.120.10 26 263 1.2E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS25655 2d676b1fc0f4b353904b4ce25638708f 306 Pfam PF05726 Pirin C-terminal cupin domain 192 290 1.5E-25 T 06-07-2017 IPR008778 Pirin, C-terminal domain CAK95_RS25655 2d676b1fc0f4b353904b4ce25638708f 306 Pfam PF02678 Pirin 34 139 2.7E-36 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAK95_RS25655 2d676b1fc0f4b353904b4ce25638708f 306 SUPERFAMILY SSF51182 22 303 1.15E-85 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS16545 0bd43823091f925e8fec1a2adc600d61 124 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 60 114 2.0E-10 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS16545 0bd43823091f925e8fec1a2adc600d61 124 SUPERFAMILY SSF74653 41 119 3.79E-12 T 06-07-2017 CAK95_RS16545 0bd43823091f925e8fec1a2adc600d61 124 Gene3D G3DSA:3.30.1150.10 61 123 6.4E-12 T 06-07-2017 CAK95_RS16545 0bd43823091f925e8fec1a2adc600d61 124 Pfam PF13103 TonB C terminal 58 117 5.1E-9 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS01970 bef155dc0ba7fc18db10841e4979388b 154 Pfam PF07883 Cupin domain 72 141 5.2E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS01970 bef155dc0ba7fc18db10841e4979388b 154 SUPERFAMILY SSF51182 44 152 5.49E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS01970 bef155dc0ba7fc18db10841e4979388b 154 Gene3D G3DSA:2.60.120.10 44 143 1.3E-16 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS28055 d4d2313179f41b4b40b7ecb6e203cbb9 199 SUPERFAMILY SSF46785 55 136 7.12E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28055 d4d2313179f41b4b40b7ecb6e203cbb9 199 Pfam PF03551 Transcriptional regulator PadR-like family 59 128 1.6E-16 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK95_RS28055 d4d2313179f41b4b40b7ecb6e203cbb9 199 Gene3D G3DSA:1.10.10.10 48 142 1.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05750 13740e19407189057470d35610ed381e 378 Gene3D G3DSA:3.20.20.210 110 374 1.3E-53 T 06-07-2017 CAK95_RS05750 13740e19407189057470d35610ed381e 378 Gene3D G3DSA:3.20.20.210 33 72 1.3E-53 T 06-07-2017 CAK95_RS05750 13740e19407189057470d35610ed381e 378 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 175 368 3.1E-6 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS05750 13740e19407189057470d35610ed381e 378 SUPERFAMILY SSF51726 108 369 3.27E-40 T 06-07-2017 CAK95_RS05750 13740e19407189057470d35610ed381e 378 SUPERFAMILY SSF51726 9 70 3.27E-40 T 06-07-2017 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 SUPERFAMILY SSF51905 1 53 3.24E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 SUPERFAMILY SSF51905 114 267 3.24E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 SUPERFAMILY SSF51905 354 412 3.24E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Gene3D G3DSA:3.30.9.10 257 352 8.1E-5 T 06-07-2017 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Gene3D G3DSA:3.50.50.60 185 256 3.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Gene3D G3DSA:3.50.50.60 138 139 3.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Gene3D G3DSA:3.50.50.60 1 57 3.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Gene3D G3DSA:3.50.50.60 354 412 3.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 SUPERFAMILY SSF54373 268 354 5.49E-10 T 06-07-2017 CAK95_RS11815 9a3cdbd7f1841b1c3eaf00bbd52e2064 415 Pfam PF01266 FAD dependent oxidoreductase 2 393 2.6E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 Pfam PF00561 alpha/beta hydrolase fold 41 274 6.3E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 232 246 1.2E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.2E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 1.2E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 1.2E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 SUPERFAMILY SSF53474 17 286 8.31E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01475 9f7a4d33bc8fda15789481846521c254 289 Gene3D G3DSA:3.40.50.1820 17 286 1.3E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS24030 d88691c18ced4db94a2c5afd30fa3e66 165 SMART SM00448 43 155 0.0025 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS24030 d88691c18ced4db94a2c5afd30fa3e66 165 Gene3D G3DSA:3.40.50.2300 45 163 5.1E-18 T 06-07-2017 CAK95_RS24030 d88691c18ced4db94a2c5afd30fa3e66 165 Pfam PF00072 Response regulator receiver domain 46 151 1.4E-9 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS24030 d88691c18ced4db94a2c5afd30fa3e66 165 SUPERFAMILY SSF52172 45 161 1.42E-15 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 Pfam PF13229 Right handed beta helix region 164 317 1.7E-15 T 06-07-2017 CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 TIGRFAM TIGR03808 RR_plus_rpt_1: twin-arg-translocated uncharacterized repeat protein 1 450 1.5E-155 T 06-07-2017 IPR022388 Conserved hypothetical protein CHP03808 CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 TIGRFAM TIGR03807 RR_fam_repeat: putative cofactor-binding repeat 345 363 7.9E-5 T 06-07-2017 IPR022444 Cofactor-binding repeat, putative CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 Gene3D G3DSA:2.160.20.10 285 417 1.6E-23 T 06-07-2017 IPR012334 Pectin lyase fold CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 Gene3D G3DSA:2.160.20.10 40 213 1.6E-23 T 06-07-2017 IPR012334 Pectin lyase fold CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 145 167 1.9 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 296 317 87.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 217 248 1000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 272 294 2200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 349 371 800.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 249 271 3300.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 190 212 2.1 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SMART SM00710 375 396 210.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAK95_RS18695 740d3fe72b9390613fdc592973024b66 450 SUPERFAMILY SSF51126 38 394 6.83E-36 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 Hamap MF_00015 LexA repressor [lexA]. 1 238 33.738 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 Gene3D G3DSA:2.10.109.10 115 238 1.2E-38 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 191 203 1.8E-9 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 151 161 1.8E-9 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 162 173 1.8E-9 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 Pfam PF00717 Peptidase S24-like 154 217 4.4E-13 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 Gene3D G3DSA:1.10.10.10 2 67 3.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 SUPERFAMILY SSF46785 2 68 1.74E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 TIGRFAM TIGR00498 lexA: repressor LexA 2 237 1.2E-54 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 Pfam PF01726 LexA DNA binding domain 2 63 7.3E-16 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CAK95_RS23065 98546ebb31d891ee3e3002bfdbd2a0a7 238 SUPERFAMILY SSF51306 113 236 1.67E-30 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS07525 29561c0ca3ccfcb7f73a68295ce915c2 246 Pfam PF00005 ABC transporter 31 177 1.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS07525 29561c0ca3ccfcb7f73a68295ce915c2 246 SMART SM00382 40 228 1.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07525 29561c0ca3ccfcb7f73a68295ce915c2 246 Gene3D G3DSA:3.40.50.300 14 232 5.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07525 29561c0ca3ccfcb7f73a68295ce915c2 246 SUPERFAMILY SSF52540 13 232 5.7E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07525 29561c0ca3ccfcb7f73a68295ce915c2 246 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25470 a6883a75c6309287ed1309ffeeef858e 257 SMART SM00382 33 214 7.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS25470 a6883a75c6309287ed1309ffeeef858e 257 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS25470 a6883a75c6309287ed1309ffeeef858e 257 SUPERFAMILY SSF52540 5 223 5.32E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25470 a6883a75c6309287ed1309ffeeef858e 257 Gene3D G3DSA:3.40.50.300 4 220 1.7E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS25470 a6883a75c6309287ed1309ffeeef858e 257 Pfam PF00005 ABC transporter 24 163 1.7E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS07720 9a89ac892f8b63634cd614339fcdf83e 201 Pfam PF00694 Aconitase C-terminal domain 1 123 3.6E-39 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAK95_RS07720 9a89ac892f8b63634cd614339fcdf83e 201 SUPERFAMILY SSF52016 1 191 5.3E-58 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS07720 9a89ac892f8b63634cd614339fcdf83e 201 Gene3D G3DSA:3.20.19.10 1 192 6.2E-50 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS07720 9a89ac892f8b63634cd614339fcdf83e 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 5.0E-80 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAK95_RS07720 9a89ac892f8b63634cd614339fcdf83e 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 201 42.295 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAK95_RS06170 31aebf9a430abd15a402ac5d63cda411 256 SMART SM00882 7 216 4.2E-41 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK95_RS06170 31aebf9a430abd15a402ac5d63cda411 256 Gene3D G3DSA:3.40.810.20 2 243 7.7E-93 T 06-07-2017 CAK95_RS06170 31aebf9a430abd15a402ac5d63cda411 256 SUPERFAMILY SSF100950 1 245 2.44E-73 T 06-07-2017 CAK95_RS06170 31aebf9a430abd15a402ac5d63cda411 256 Pfam PF01144 Coenzyme A transferase 7 215 2.2E-47 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK95_RS17645 c330557a44e95faa5211c961193e90c0 346 Pfam PF00953 Glycosyl transferase family 4 91 237 6.0E-27 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAK95_RS25225 43e04d24f4584a989ded87b63a8a8600 392 Gene3D G3DSA:3.40.640.10 53 259 2.2E-53 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS25225 43e04d24f4584a989ded87b63a8a8600 392 Pfam PF00155 Aminotransferase class I and II 41 385 1.2E-48 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS25225 43e04d24f4584a989ded87b63a8a8600 392 Gene3D G3DSA:3.90.1150.10 260 390 1.0E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS25225 43e04d24f4584a989ded87b63a8a8600 392 SUPERFAMILY SSF53383 16 390 8.94E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 88 240 1.8E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 Gene3D G3DSA:1.10.1740.10 81 157 2.7E-14 T 06-07-2017 CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 Gene3D G3DSA:1.10.10.10 183 241 9.9E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 SUPERFAMILY SSF88659 170 241 1.05E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 Pfam PF04542 Sigma-70 region 2 92 156 7.4E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 Pfam PF08281 Sigma-70, region 4 188 240 2.5E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04875 42ee833203ba12202240e8e3a6847934 246 SUPERFAMILY SSF88946 80 175 2.83E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15000 3e821e6545cc34ddf1b0b65d132b4669 154 Pfam PF13501 Sulfur oxidation protein SoxY 42 149 4.3E-30 T 06-07-2017 IPR032711 Ig-like SoxY domain CAK95_RS15000 3e821e6545cc34ddf1b0b65d132b4669 154 PIRSF PIRSF010312 1 151 4.1E-40 T 06-07-2017 IPR016568 Sulphur oxidation, SoxY CAK95_RS15000 3e821e6545cc34ddf1b0b65d132b4669 154 TIGRFAM TIGR04487 SoxY_para_1: SoxY-related AACIE arm protein 12 151 6.2E-61 T 06-07-2017 IPR030997 SoxY-related AACIE arm protein CAK95_RS10735 4b741b976e459e644e05e4027e640b81 320 Gene3D G3DSA:2.20.25.10 28 78 2.8E-10 T 06-07-2017 CAK95_RS10735 4b741b976e459e644e05e4027e640b81 320 Pfam PF08241 Methyltransferase domain 123 213 2.1E-13 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS10735 4b741b976e459e644e05e4027e640b81 320 SUPERFAMILY SSF53335 101 288 1.0E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10735 4b741b976e459e644e05e4027e640b81 320 SUPERFAMILY SSF158997 21 68 1.28E-10 T 06-07-2017 CAK95_RS10735 4b741b976e459e644e05e4027e640b81 320 Gene3D G3DSA:3.40.50.150 111 299 8.1E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS18235 f9fb3c42bcc51da1e6c05fe0f79011e3 1198 Gene3D G3DSA:1.25.40.10 777 890 7.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18235 f9fb3c42bcc51da1e6c05fe0f79011e3 1198 Gene3D G3DSA:1.25.40.10 638 735 7.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18235 f9fb3c42bcc51da1e6c05fe0f79011e3 1198 Gene3D G3DSA:1.25.40.10 1025 1063 7.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18235 f9fb3c42bcc51da1e6c05fe0f79011e3 1198 SUPERFAMILY SSF48452 771 889 4.94E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18235 f9fb3c42bcc51da1e6c05fe0f79011e3 1198 SUPERFAMILY SSF48452 639 729 4.94E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS13250 f5fdfd67f89fe9f11e92a9959247e6e1 154 SUPERFAMILY SSF54427 6 132 4.28E-28 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS13250 f5fdfd67f89fe9f11e92a9959247e6e1 154 Gene3D G3DSA:3.10.450.50 6 139 3.1E-31 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS13250 f5fdfd67f89fe9f11e92a9959247e6e1 154 Pfam PF12680 SnoaL-like domain 10 119 1.1E-18 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 Gene3D G3DSA:3.40.50.1100 111 202 1.9E-9 T 06-07-2017 CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 396 1.8E-18 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 SUPERFAMILY SSF53686 2 459 9.4E-157 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 Pfam PF14821 Threonine synthase N terminus 3 80 2.6E-25 T 06-07-2017 IPR029144 Threonine synthase, N-terminal CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 Gene3D G3DSA:3.40.50.1100 203 435 1.3E-92 T 06-07-2017 CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 Gene3D G3DSA:3.90.1380.10 3 85 2.5E-25 T 06-07-2017 IPR029144 Threonine synthase, N-terminal CAK95_RS05510 0f3884b83120011be2eca4d39f91f97b 471 TIGRFAM TIGR00260 thrC: threonine synthase 70 427 1.7E-83 T 06-07-2017 IPR004450 Threonine synthase-like CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 336 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 345 366 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 398 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 275 296 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 408 427 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 458 479 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 131 2.5E-70 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 555 8.6E-203 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 505 1.5E-133 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 Gene3D G3DSA:1.20.210.10 24 578 2.1E-179 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 SUPERFAMILY SSF81442 28 551 3.27E-155 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05170 20a219699e515c312bf53733e0370433 587 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 277 331 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 SUPERFAMILY SSF52540 5 245 2.09E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 SMART SM00382 30 223 1.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 3.6E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 Gene3D G3DSA:3.40.50.300 3 243 6.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 Pfam PF00005 ABC transporter 21 177 2.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11660 1a41fb9eab6450f87003f9f446082bdf 251 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 SUPERFAMILY SSF53850 87 295 3.44E-43 T 06-07-2017 CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 Gene3D G3DSA:3.40.190.10 90 174 9.3E-23 T 06-07-2017 CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 SUPERFAMILY SSF46785 4 86 1.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 Pfam PF03466 LysR substrate binding domain 86 292 9.4E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 Gene3D G3DSA:3.40.190.10 175 258 1.3E-16 T 06-07-2017 CAK95_RS28260 58e16fa61e645665de68b7ad138b33a0 299 Gene3D G3DSA:1.10.10.10 3 86 1.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06225 4cbfacfea5cbed7de128c39f4e84651a 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 429 7.6E-100 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS06225 4cbfacfea5cbed7de128c39f4e84651a 432 PIRSF PIRSF006066 5 432 8.3E-97 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS06225 4cbfacfea5cbed7de128c39f4e84651a 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 5.1E-114 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS04435 503edeb58e8e83b31e8d0620b9a8e465 292 SUPERFAMILY SSF88713 5 289 4.7E-69 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS04435 503edeb58e8e83b31e8d0620b9a8e465 292 Gene3D G3DSA:3.20.20.370 5 286 3.0E-71 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS04435 503edeb58e8e83b31e8d0620b9a8e465 292 Pfam PF01522 Polysaccharide deacetylase 69 175 2.0E-13 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.1E-39 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.1E-39 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.1E-39 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.1E-39 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.1E-39 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 Gene3D G3DSA:3.50.50.60 154 340 8.2E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 473 6.5E-180 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 Gene3D G3DSA:3.30.390.30 341 470 2.1E-47 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 334 1.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 SUPERFAMILY SSF55424 350 472 1.41E-39 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PIRSF PIRSF000350 1 470 7.9E-83 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 5.7E-37 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 SUPERFAMILY SSF51905 2 343 6.37E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 1.2E-65 T 06-07-2017 CAK95_RS23190 d8a2021433917d19220d7bcd25675874 473 Gene3D G3DSA:3.50.50.60 5 153 4.8E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 235 4.5E-38 T 06-07-2017 CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 SUPERFAMILY SSF51735 1 238 1.72E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS12915 4ff2dcb7a565dbd77ef3d7fe0578d5de 239 Gene3D G3DSA:3.40.50.720 2 238 5.7E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS02965 b4030970a399724280a3bce637ac43af 148 SUPERFAMILY SSF109709 52 110 3.27E-9 T 06-07-2017 CAK95_RS11595 46d539ad62f957ed2fe640839681ed39 325 Gene3D G3DSA:1.10.10.10 33 74 7.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11595 46d539ad62f957ed2fe640839681ed39 325 SUPERFAMILY SSF100950 73 324 5.02E-59 T 06-07-2017 CAK95_RS11595 46d539ad62f957ed2fe640839681ed39 325 Gene3D G3DSA:3.40.50.1360 75 324 4.7E-68 T 06-07-2017 CAK95_RS11595 46d539ad62f957ed2fe640839681ed39 325 Pfam PF04198 Putative sugar-binding domain 72 324 5.2E-60 T 06-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 4 689 4.4E-304 T 06-07-2017 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Gene3D G3DSA:3.40.50.300 451 680 8.4E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 SMART SM00382 477 663 6.5E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Pfam PF00005 ABC transporter 468 617 1.9E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 ProSitePatterns PS00211 ABC transporters family signature. 589 603 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Pfam PF03412 Peptidase C39 family 1 110 2.7E-9 T 06-07-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Gene3D G3DSA:1.20.1560.10 123 435 8.9E-80 T 06-07-2017 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 SUPERFAMILY SSF90123 123 435 2.49E-69 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 SUPERFAMILY SSF52540 440 687 1.28E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Pfam PF00664 ABC transporter transmembrane region 138 402 1.5E-54 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS10825 78d0bc2e281b7f497dbcb5efdfa0b453 694 Gene3D G3DSA:3.90.70.10 1 110 2.3E-18 T 06-07-2017 CAK95_RS18535 26cb6b996cfce935de2e12c9571495ab 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 10 422 3.9E-92 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS18535 26cb6b996cfce935de2e12c9571495ab 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 1 417 1.3E-76 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS18535 26cb6b996cfce935de2e12c9571495ab 426 PIRSF PIRSF006066 1 426 5.4E-82 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 Gene3D G3DSA:1.10.1040.10 163 293 2.1E-27 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 SUPERFAMILY SSF51735 5 161 2.88E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 2.0E-28 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 160 5.7E-31 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 SUPERFAMILY SSF48179 164 293 1.47E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 PIRSF PIRSF000103 1 294 3.3E-51 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS01065 09f9f3c72f1d2cd1c5493b0d5c551aaa 306 Gene3D G3DSA:3.40.50.720 3 161 1.6E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 63 74 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 SUPERFAMILY SSF56059 97 300 1.68E-46 T 06-07-2017 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 SUPERFAMILY SSF52440 1 95 3.36E-29 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Gene3D G3DSA:3.30.1490.20 96 152 3.8E-9 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Gene3D G3DSA:3.30.470.20 86 95 1.3E-43 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Gene3D G3DSA:3.30.470.20 170 302 1.3E-43 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Pfam PF07478 D-ala D-ala ligase C-terminus 124 300 1.1E-40 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Gene3D G3DSA:3.40.50.20 2 83 2.2E-27 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 303 32.394 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 241 273 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 Pfam PF01820 D-ala D-ala ligase N-terminus 5 84 1.7E-19 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01770 21f639e2f96142a9cc9f0a039d78f017 306 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 302 2.6E-80 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS13410 6faf4fd7720c3b10347b0fbab20e7c5d 237 Pfam PF04028 Domain of unknown function (DUF374) 68 141 1.6E-24 T 06-07-2017 IPR007172 Domain of unknown function DUF374 CAK95_RS13410 6faf4fd7720c3b10347b0fbab20e7c5d 237 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 7 138 4.0E-41 T 06-07-2017 IPR007172 Domain of unknown function DUF374 CAK95_RS05010 aaeefb5b8fdce9c0c683cf743ebf8c0c 284 Pfam PF11769 Protein of unknown function (DUF3313) 18 212 7.9E-36 T 06-07-2017 IPR021747 Protein of unknown function DUF3313 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 SMART SM00342 231 315 4.7E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 Gene3D G3DSA:1.10.10.60 268 314 1.4E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 SUPERFAMILY SSF51215 58 117 1.83E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 SUPERFAMILY SSF46689 267 317 6.27E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 Pfam PF14525 AraC-binding-like domain 26 199 1.0E-29 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 Pfam PF12833 Helix-turn-helix domain 240 317 7.4E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 SUPERFAMILY SSF46689 216 264 5.38E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 268 311 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS27315 b2df1ee5a27256871bbb955e655c2ab0 320 Gene3D G3DSA:1.10.10.60 216 267 1.9E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS06050 f3cd5a1bc23dc4a5558f5aa1b2ce62cd 237 Pfam PF13466 STAS domain 1 73 5.9E-8 T 06-07-2017 IPR002645 STAS domain CAK95_RS06050 f3cd5a1bc23dc4a5558f5aa1b2ce62cd 237 SMART SM00448 119 232 1.6E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06050 f3cd5a1bc23dc4a5558f5aa1b2ce62cd 237 Gene3D G3DSA:3.40.50.2300 117 235 6.2E-37 T 06-07-2017 CAK95_RS06050 f3cd5a1bc23dc4a5558f5aa1b2ce62cd 237 SUPERFAMILY SSF52172 119 235 1.57E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06050 f3cd5a1bc23dc4a5558f5aa1b2ce62cd 237 Pfam PF00072 Response regulator receiver domain 121 232 4.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06570 69050fb112239b2629e387cd116fa038 175 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 159 8.9E-49 T 06-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CAK95_RS06570 69050fb112239b2629e387cd116fa038 175 Gene3D G3DSA:3.40.50.300 1 162 9.5E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06570 69050fb112239b2629e387cd116fa038 175 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 135 6.1E-53 T 06-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CAK95_RS06570 69050fb112239b2629e387cd116fa038 175 SUPERFAMILY SSF52540 1 160 4.3E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14745 e2805dea2a46d3c602b349c4c4e3a06a 338 SUPERFAMILY SSF53850 135 302 1.23E-6 T 06-07-2017 CAK95_RS14745 e2805dea2a46d3c602b349c4c4e3a06a 338 PIRSF PIRSF017082 13 338 2.5E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14745 e2805dea2a46d3c602b349c4c4e3a06a 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 334 1.2E-60 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12715 d79331292906ac0f847742a9cd4361c1 335 Gene3D G3DSA:3.40.50.1820 103 181 4.6E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 Gene3D G3DSA:3.50.50.60 367 432 2.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 Gene3D G3DSA:3.50.50.60 21 249 2.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 Pfam PF12831 FAD dependent oxidoreductase 23 439 3.6E-107 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 SUPERFAMILY SSF51905 7 187 2.05E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 SUPERFAMILY SSF51905 356 417 2.05E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 SUPERFAMILY SSF51905 289 304 2.05E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26125 7fc441f2c872cb7b35c1c1497bc71ba3 449 SUPERFAMILY SSF51905 228 236 2.05E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82866 788 1014 1.44E-41 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82714 701 789 6.02E-10 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82866 294 490 2.09E-42 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:1.20.1640.10 303 497 1.1E-48 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 533 550 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 2.6E-55 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82693 547 649 1.52E-12 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82693 41 134 1.55E-23 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82693 268 312 2.14E-9 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82693 139 182 2.14E-9 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.70.1430 548 649 1.9E-10 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 SUPERFAMILY SSF82714 185 265 5.1E-12 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.2090.10 701 789 1.4E-8 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.2090.10 185 264 2.7E-12 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Pfam PF00873 AcrB/AcrD/AcrF family 5 1008 1.1E-223 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:1.10.3850.10 794 1009 4.0E-48 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.70.1320 141 179 1.6E-6 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.70.1320 270 302 1.6E-6 T 06-07-2017 CAK95_RS01250 d57fa07ce387cb9d48f846473de3165c 1027 Gene3D G3DSA:3.30.70.1430 41 140 4.6E-27 T 06-07-2017 CAK95_RS11260 76389c96a8411bc417010919161c57e1 191 Gene3D G3DSA:1.20.1260.10 4 166 3.0E-63 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS11260 76389c96a8411bc417010919161c57e1 191 Pfam PF05974 Domain of unknown function (DUF892) 11 166 9.4E-58 T 06-07-2017 IPR010287 Domain of unknown function DUF892 CAK95_RS11260 76389c96a8411bc417010919161c57e1 191 SUPERFAMILY SSF47240 2 159 2.03E-50 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS25880 0f18dbcc49cd9501ffbccd4ab2128c17 415 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 178 352 7.4E-59 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAK95_RS25880 0f18dbcc49cd9501ffbccd4ab2128c17 415 Gene3D G3DSA:3.30.160.60 326 359 1.4E-13 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 CAK95_RS25880 0f18dbcc49cd9501ffbccd4ab2128c17 415 Pfam PF02618 YceG-like family 76 351 5.4E-80 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAK95_RS20030 a75aade1889118aa9afb2907ab9d118b 71 Pfam PF10932 Protein of unknown function (DUF2783) 3 61 6.3E-23 T 06-07-2017 IPR021233 Protein of unknown function DUF2783 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 Gene3D G3DSA:1.10.760.10 301 406 3.4E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 SUPERFAMILY SSF46626 27 149 6.18E-22 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 Pfam PF00034 Cytochrome c 32 130 1.1E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 PIRSF PIRSF000018 3 409 2.1E-130 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 PRINTS PR00605 Class IC cytochrome C signature 307 318 9.1E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 PRINTS PR00605 Class IC cytochrome C signature 360 382 9.1E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 SUPERFAMILY SSF46626 173 280 6.04E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 298 382 7.9E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 SUPERFAMILY SSF46626 300 402 7.13E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 Gene3D G3DSA:1.10.760.10 172 280 7.5E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14765 54808b1f9c71f700adc859e340ce091f 409 Gene3D G3DSA:1.10.760.10 29 130 9.2E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS19865 7567a889f428895279dc876e3c021580 554 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 14 513 4.2E-123 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS16375 8643fdc4a18f3be98d0523b26b2a85d7 116 Pfam PF04342 Putative member of DMT superfamily (DUF486) 10 113 3.6E-44 T 06-07-2017 IPR007437 Putative member of DMT superfamily CAK95_RS16375 8643fdc4a18f3be98d0523b26b2a85d7 116 PIRSF PIRSF021239 4 116 1.2E-47 T 06-07-2017 IPR007437 Putative member of DMT superfamily CAK95_RS06380 781612d92af28ade9945990ec81cf6a8 99 Gene3D G3DSA:2.60.120.10 7 98 9.7E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS06380 781612d92af28ade9945990ec81cf6a8 99 SUPERFAMILY SSF51182 8 90 5.18E-17 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS06380 781612d92af28ade9945990ec81cf6a8 99 Pfam PF07883 Cupin domain 18 77 2.6E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS27915 d8449424d73a1e02584a501aa8478b99 370 PIRSF PIRSF007313 1 362 4.2E-160 T 06-07-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CAK95_RS27915 d8449424d73a1e02584a501aa8478b99 370 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 352 1.7E-163 T 06-07-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CAK95_RS26960 bca5389b9848cfd726462973bb7ec6ce 69 SUPERFAMILY SSF53098 6 60 3.03E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS26960 bca5389b9848cfd726462973bb7ec6ce 69 Pfam PF13683 Integrase core domain 10 48 1.2E-8 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK95_RS26960 bca5389b9848cfd726462973bb7ec6ce 69 Gene3D G3DSA:3.30.420.10 6 48 2.6E-4 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 SUPERFAMILY SSF53335 265 296 1.99E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 SUPERFAMILY SSF53335 108 229 1.99E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 Gene3D G3DSA:3.40.50.150 263 294 2.3E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 Gene3D G3DSA:3.40.50.150 134 185 2.3E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 Gene3D G3DSA:3.40.50.150 220 221 2.3E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26900 3902b70962ca732752eba9b58fc895cf 319 Pfam PF08241 Methyltransferase domain 121 175 1.6E-9 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 127 8.1E-21 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 Gene3D G3DSA:3.30.360.10 306 361 3.8E-19 T 06-07-2017 CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 Gene3D G3DSA:3.30.360.10 144 268 3.8E-19 T 06-07-2017 CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 SUPERFAMILY SSF55347 135 271 4.8E-13 T 06-07-2017 CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 Gene3D G3DSA:3.40.50.720 4 143 1.8E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13455 1d8a1d26e7f22ca3be5f366386ef8dda 375 SUPERFAMILY SSF51735 6 156 2.48E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26695 783208d102fdbf33bed9ee3a273cb729 473 Pfam PF01425 Amidase 25 447 1.6E-107 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS26695 783208d102fdbf33bed9ee3a273cb729 473 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK95_RS26695 783208d102fdbf33bed9ee3a273cb729 473 Gene3D G3DSA:3.90.1300.10 7 467 1.3E-138 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS26695 783208d102fdbf33bed9ee3a273cb729 473 SUPERFAMILY SSF75304 4 458 1.1E-135 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23850 7d457821297735f388079f19c7f2985e 357 SUPERFAMILY SSF56112 21 164 2.45E-11 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS23850 7d457821297735f388079f19c7f2985e 357 Gene3D G3DSA:3.30.300.30 242 321 6.2E-12 T 06-07-2017 CAK95_RS23850 7d457821297735f388079f19c7f2985e 357 Pfam PF13193 AMP-binding enzyme C-terminal domain 244 310 6.7E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS23850 7d457821297735f388079f19c7f2985e 357 SUPERFAMILY SSF56801 242 324 1.31E-10 T 06-07-2017 CAK95_RS23850 7d457821297735f388079f19c7f2985e 357 Gene3D G3DSA:1.10.510.10 110 190 3.3E-6 T 06-07-2017 CAK95_RS21665 cc27a88c2ffd8ee254a5d0431fed29c9 292 SUPERFAMILY SSF103481 47 142 9.29E-14 T 06-07-2017 CAK95_RS21665 cc27a88c2ffd8ee254a5d0431fed29c9 292 SUPERFAMILY SSF103481 198 291 6.28E-16 T 06-07-2017 CAK95_RS21665 cc27a88c2ffd8ee254a5d0431fed29c9 292 Pfam PF00892 EamA-like transporter family 15 142 4.2E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS21665 cc27a88c2ffd8ee254a5d0431fed29c9 292 Pfam PF00892 EamA-like transporter family 155 288 1.9E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS08390 97d9ba0faacc03539256e0b6e88696fc 152 Pfam PF03061 Thioesterase superfamily 32 113 3.7E-10 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS08390 97d9ba0faacc03539256e0b6e88696fc 152 SUPERFAMILY SSF54637 16 151 2.93E-28 T 06-07-2017 IPR029069 HotDog domain CAK95_RS08390 97d9ba0faacc03539256e0b6e88696fc 152 Gene3D G3DSA:3.10.129.10 16 151 1.7E-33 T 06-07-2017 IPR029069 HotDog domain CAK95_RS20540 40b9a2938b0120e6634a7de831c3949d 161 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 138 1.6E-22 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS20540 40b9a2938b0120e6634a7de831c3949d 161 SUPERFAMILY SSF46785 2 140 7.18E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20540 40b9a2938b0120e6634a7de831c3949d 161 Pfam PF02082 Transcriptional regulator 1 83 4.6E-21 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS20540 40b9a2938b0120e6634a7de831c3949d 161 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 06-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site CAK95_RS20540 40b9a2938b0120e6634a7de831c3949d 161 Gene3D G3DSA:1.10.10.10 1 149 4.4E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25995 48e63fb333823f25d46c566ed0d40a78 144 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 97 1.8E-20 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS25995 48e63fb333823f25d46c566ed0d40a78 144 Gene3D G3DSA:1.20.1290.10 13 142 1.4E-41 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS25995 48e63fb333823f25d46c566ed0d40a78 144 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 32 79 4.4E-15 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS25995 48e63fb333823f25d46c566ed0d40a78 144 SUPERFAMILY SSF69118 13 142 3.14E-38 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS16995 0e96533a0159b1b50de3330d09489ba7 390 SUPERFAMILY SSF53850 135 253 8.81E-25 T 06-07-2017 CAK95_RS16995 0e96533a0159b1b50de3330d09489ba7 390 SUPERFAMILY SSF53850 4 108 8.81E-25 T 06-07-2017 CAK95_RS16995 0e96533a0159b1b50de3330d09489ba7 390 Pfam PF13379 NMT1-like family 3 264 2.4E-72 T 06-07-2017 CAK95_RS16995 0e96533a0159b1b50de3330d09489ba7 390 Gene3D G3DSA:3.40.190.10 138 242 2.3E-9 T 06-07-2017 CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 SUPERFAMILY SSF51735 3 159 1.83E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 172 271 1.8E-16 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 SUPERFAMILY SSF48179 170 278 3.17E-19 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 Gene3D G3DSA:3.40.50.720 3 165 2.5E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 Gene3D G3DSA:1.10.1040.10 172 301 2.5E-24 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 165 3.1E-32 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS16815 c2114ee839ec5d1fbfb3e85904640897 317 PIRSF PIRSF000103 1 301 3.0E-51 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 SMART SM00342 225 310 1.7E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 Pfam PF12833 Helix-turn-helix domain 232 311 5.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 Pfam PF14525 AraC-binding-like domain 22 170 6.0E-19 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 SUPERFAMILY SSF46689 261 312 3.36E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 306 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 Gene3D G3DSA:1.10.10.60 260 312 2.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 294 310 5.9E-8 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS16485 b6adca459432182dc641844d60c36a96 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 5.9E-8 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS25260 6b6f35eb278801142d27e5acebe3d556 210 PIRSF PIRSF033303 1 210 8.1E-80 T 06-07-2017 IPR014581 Uncharacterised conserved protein UCP033303 CAK95_RS25260 6b6f35eb278801142d27e5acebe3d556 210 Pfam PF07040 Protein of unknown function (DUF1326) 14 194 2.0E-54 T 06-07-2017 IPR009758 Protein of unknown function DUF1326 CAK95_RS02055 171660bea069530404a79fce2cb0f23c 395 SUPERFAMILY SSF51730 98 388 8.04E-61 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS02055 171660bea069530404a79fce2cb0f23c 395 Gene3D G3DSA:3.20.20.220 96 391 5.8E-49 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS02055 171660bea069530404a79fce2cb0f23c 395 Pfam PF02219 Methylenetetrahydrofolate reductase 99 387 3.5E-34 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS13015 4a7fecdd32f1e5565663e720d82bcc8d 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 333 2.8E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 564 745 5.7E-57 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 SUPERFAMILY SSF158472 364 414 7.32E-10 T 06-07-2017 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 SMART SM00304 446 498 3.0E-4 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 SMART SM00304 364 417 1.6E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 SMART SM00283 499 746 3.5E-94 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 Pfam PF00672 HAMP domain 346 413 5.3E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 Gene3D G3DSA:1.10.287.950 514 718 4.5E-60 T 06-07-2017 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 597 624 1.4E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 520 549 1.4E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 674 703 1.4E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 626 655 1.4E-51 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 SUPERFAMILY SSF58104 466 747 5.23E-70 T 06-07-2017 CAK95_RS24105 ab3810dd6e82fdef6a089132c9ff1b2f 800 Pfam PF12729 Four helix bundle sensory module for signal transduction 20 182 5.1E-7 T 06-07-2017 IPR024478 4HB MCP domain CAK95_RS03700 23db6a6cf90017c0e2f3bb8c6da87b23 688 SUPERFAMILY SSF101898 542 586 1.86E-18 T 06-07-2017 CAK95_RS03700 23db6a6cf90017c0e2f3bb8c6da87b23 688 SUPERFAMILY SSF101898 284 500 1.86E-18 T 06-07-2017 CAK95_RS03700 23db6a6cf90017c0e2f3bb8c6da87b23 688 Gene3D G3DSA:2.120.10.30 291 498 3.1E-19 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS03700 23db6a6cf90017c0e2f3bb8c6da87b23 688 Gene3D G3DSA:2.120.10.30 540 584 3.1E-19 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS13395 f5376f0eae97238fcc4e8a4f226666fa 63 Pfam PF09866 Uncharacterized protein conserved in bacteria (DUF2093) 16 57 2.8E-23 T 06-07-2017 IPR018661 Protein of unknown function DUF2093 CAK95_RS09690 c791447a2e2d02519c0f141f43e8fed0 179 SMART SM00226 10 148 3.7E-28 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS09690 c791447a2e2d02519c0f141f43e8fed0 179 Gene3D G3DSA:3.40.50.270 9 144 7.6E-36 T 06-07-2017 CAK95_RS09690 c791447a2e2d02519c0f141f43e8fed0 179 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 127 1.4E-15 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS09690 c791447a2e2d02519c0f141f43e8fed0 179 SUPERFAMILY SSF52788 10 148 1.26E-36 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS03440 b41bcc2d49c48d420ec646bb1256d58b 152 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 38 149 6.2E-25 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS03440 b41bcc2d49c48d420ec646bb1256d58b 152 Pfam PF05119 Phage terminase, small subunit 45 137 1.9E-26 T 06-07-2017 IPR006448 Putative phage terminase, small subunit, P27 family CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 246 296 5.7E-5 T 06-07-2017 IPR013615 CbbQ/NirQ/NorQ, C-terminal CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 14 329 5.0E-194 T 06-07-2017 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 Gene3D G3DSA:3.40.50.300 61 233 3.5E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 Pfam PF07728 AAA domain (dynein-related subfamily) 71 193 1.4E-11 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 SUPERFAMILY SSF52540 43 288 1.82E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10530 f97afbaa9715d8dd3343826bdfc3296b 332 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 14 44 5.4E-19 T 06-07-2017 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CAK95_RS19755 66776daa8f5a3e533ed49ac37db1225f 458 SUPERFAMILY SSF56801 82 361 4.19E-10 T 06-07-2017 CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 Pfam PF13410 Glutathione S-transferase, C-terminal domain 128 192 3.2E-8 T 06-07-2017 CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 Gene3D G3DSA:1.20.1050.10 87 215 9.4E-28 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 SUPERFAMILY SSF52833 1 106 4.41E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 Gene3D G3DSA:3.40.30.10 1 82 4.1E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 SUPERFAMILY SSF47616 85 209 2.27E-22 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS11960 4d42b49428dcb1096099d716d79da28e 219 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 82 2.7E-11 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS06325 7380cf05e182754fce51e181d8b525e9 278 Pfam PF01061 ABC-2 type transporter 41 232 5.9E-11 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 356 374 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 435 452 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 411 426 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 398 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 115 133 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 152 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 233 249 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 262 281 1.9E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 SUPERFAMILY SSF56235 10 538 1.04E-160 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS04950 764fda3cb7d61225409e84400d04c68b 540 Pfam PF01019 Gamma-glutamyltranspeptidase 36 535 3.8E-139 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 SUPERFAMILY SSF48498 82 207 4.13E-35 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 Gene3D G3DSA:1.10.10.60 4 62 1.2E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 Pfam PF08362 YcdC-like protein, C-terminal region 75 208 4.2E-5 T 06-07-2017 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 Gene3D G3DSA:1.10.357.10 63 210 6.6E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS05955 097c710a44163b251b1dbdc3c688c1da 214 SUPERFAMILY SSF46689 5 83 2.57E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 Pfam PF09339 IclR helix-turn-helix domain 19 68 2.4E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 Gene3D G3DSA:3.30.450.40 85 263 4.2E-40 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 Gene3D G3DSA:1.10.10.10 15 84 6.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 SMART SM00346 16 106 3.7E-21 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 SUPERFAMILY SSF55781 82 262 5.04E-34 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 Pfam PF01614 Bacterial transcriptional regulator 134 259 1.1E-13 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS02175 723d39f1ce8b366e3daf7f0230ef73f0 266 SUPERFAMILY SSF46785 16 90 7.87E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23670 cc6b682d890d56bd1d82d2c2a68e6d40 551 ProSitePatterns PS00587 Glycosyl hydrolases family 17 signature. 241 254 - T 06-07-2017 IPR000490 Glycoside hydrolase family 17 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.39 CAK95_RS23670 cc6b682d890d56bd1d82d2c2a68e6d40 551 Gene3D G3DSA:3.20.20.80 71 320 3.1E-27 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK95_RS23670 cc6b682d890d56bd1d82d2c2a68e6d40 551 SUPERFAMILY SSF51445 38 321 6.49E-51 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS23580 2d270920f9bd433158afbee7619d3a9f 347 PIRSF PIRSF015582 10 345 4.7E-90 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK95_RS23580 2d270920f9bd433158afbee7619d3a9f 347 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 32 275 4.1E-26 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS23580 2d270920f9bd433158afbee7619d3a9f 347 SUPERFAMILY SSF51621 24 286 5.76E-52 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS23580 2d270920f9bd433158afbee7619d3a9f 347 Gene3D G3DSA:3.20.20.60 23 286 8.5E-64 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS06490 c06ba38975661b07cc5ba6acc32d7f91 66 Pfam PF12728 Helix-turn-helix domain 6 55 2.6E-14 T 06-07-2017 CAK95_RS06490 c06ba38975661b07cc5ba6acc32d7f91 66 Gene3D G3DSA:1.10.10.10 6 57 2.6E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06490 c06ba38975661b07cc5ba6acc32d7f91 66 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 1.2E-10 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK95_RS06490 c06ba38975661b07cc5ba6acc32d7f91 66 SUPERFAMILY SSF46955 6 58 1.83E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS03920 a8a6aead75d97882afca937b4427f8ea 397 Gene3D G3DSA:1.20.1250.20 219 390 6.0E-16 T 06-07-2017 CAK95_RS03920 a8a6aead75d97882afca937b4427f8ea 397 Pfam PF07690 Major Facilitator Superfamily 25 244 2.0E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS03920 a8a6aead75d97882afca937b4427f8ea 397 Gene3D G3DSA:1.20.1250.20 23 198 7.1E-25 T 06-07-2017 CAK95_RS03920 a8a6aead75d97882afca937b4427f8ea 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK95_RS03920 a8a6aead75d97882afca937b4427f8ea 397 SUPERFAMILY SSF103473 22 394 1.96E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 SMART SM00342 170 253 2.4E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 Gene3D G3DSA:2.60.120.10 20 87 2.1E-11 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 SUPERFAMILY SSF51182 23 180 3.74E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 Gene3D G3DSA:1.10.10.60 218 252 2.9E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 Gene3D G3DSA:1.10.10.60 150 208 4.8E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 249 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 Pfam PF02311 AraC-like ligand binding domain 25 91 2.5E-7 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS20445 40c9df0a6f4ab259235b507df09da2cb 255 Pfam PF12833 Helix-turn-helix domain 177 254 1.5E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 157 1.1E-20 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 36 741 1.1E-137 T 06-07-2017 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 35 741 1.3E-180 T 06-07-2017 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 Pfam PF00593 TonB dependent receptor 452 739 6.5E-27 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 43 - T 06-07-2017 IPR010916 TonB box, conserved site CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 Gene3D G3DSA:2.40.170.20 163 741 2.8E-83 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 Gene3D G3DSA:2.170.130.10 48 162 3.9E-35 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS10850 0425215cef042d3f56c85303447d4f4a 744 SUPERFAMILY SSF56935 36 741 1.1E-99 T 06-07-2017 CAK95_RS20295 4b8e8c4a59b856eb08d68052afb7697b 250 Pfam PF00005 ABC transporter 27 171 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS20295 4b8e8c4a59b856eb08d68052afb7697b 250 SUPERFAMILY SSF52540 10 242 1.17E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20295 4b8e8c4a59b856eb08d68052afb7697b 250 SMART SM00382 36 223 1.5E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS20295 4b8e8c4a59b856eb08d68052afb7697b 250 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS20295 4b8e8c4a59b856eb08d68052afb7697b 250 Gene3D G3DSA:3.40.50.300 10 241 2.2E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18490 10ce0b066045338c25cac993f8f213b3 284 Gene3D G3DSA:3.20.20.150 8 280 5.3E-100 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS18490 10ce0b066045338c25cac993f8f213b3 284 Pfam PF05114 Protein of unknown function (DUF692) 11 275 7.0E-104 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAK95_RS18490 10ce0b066045338c25cac993f8f213b3 284 Hamap MF_00697 UPF0276 protein . 10 283 44.727 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAK95_RS18490 10ce0b066045338c25cac993f8f213b3 284 SUPERFAMILY SSF51658 27 259 2.56E-9 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS00260 1f4bf438c29ad29c6108d763cbfa0f47 187 Pfam PF04011 LemA family 9 182 1.3E-61 T 06-07-2017 IPR007156 LemA CAK95_RS00260 1f4bf438c29ad29c6108d763cbfa0f47 187 SUPERFAMILY SSF140478 24 171 1.31E-50 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS00260 1f4bf438c29ad29c6108d763cbfa0f47 187 Gene3D G3DSA:1.20.1440.20 13 182 3.3E-59 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS22735 a8d9036940416758cdce64cb886d0975 141 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 14 135 1.3E-58 T 06-07-2017 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 CAK95_RS22735 a8d9036940416758cdce64cb886d0975 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 132 3.7E-28 T 06-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 SUPERFAMILY SSF48498 134 259 1.0E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 Gene3D G3DSA:1.10.10.60 55 112 6.8E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 89 112 7.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 81 7.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 SUPERFAMILY SSF46689 56 123 1.49E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 Gene3D G3DSA:1.10.357.10 115 254 1.7E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS04915 8661c1f549bbdd78eec224c085f0edb7 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 68 112 2.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS19055 a27256c3ec4a0cee8940fc5ee3376906 105 Pfam PF11836 Phage tail tube protein, GTA-gp10 6 101 2.4E-27 T 06-07-2017 IPR021791 Phage tail tube protein, GTA-gp10 CAK95_RS08100 96c5e7a942bd0405a11edb94735405c4 265 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 11 216 4.3E-28 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK95_RS08100 96c5e7a942bd0405a11edb94735405c4 265 SUPERFAMILY SSF51197 2 255 1.56E-57 T 06-07-2017 CAK95_RS08100 96c5e7a942bd0405a11edb94735405c4 265 Gene3D G3DSA:2.60.120.620 2 230 3.2E-49 T 06-07-2017 CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 SUPERFAMILY SSF51735 7 233 3.15E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 Gene3D G3DSA:3.40.50.720 2 234 2.3E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 4.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 4.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS27160 aa6aef7c6bf2036d06fff72a4c0694e4 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 231 1.3E-50 T 06-07-2017 CAK95_RS23185 c0b8802406c871e3b7c70bef2c9d7da2 249 Pfam PF13531 Bacterial extracellular solute-binding protein 28 246 1.9E-29 T 06-07-2017 CAK95_RS23185 c0b8802406c871e3b7c70bef2c9d7da2 249 Gene3D G3DSA:3.40.190.10 26 158 1.7E-16 T 06-07-2017 CAK95_RS23185 c0b8802406c871e3b7c70bef2c9d7da2 249 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 36 243 2.5E-21 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAK95_RS23185 c0b8802406c871e3b7c70bef2c9d7da2 249 SUPERFAMILY SSF53850 27 247 3.84E-38 T 06-07-2017 CAK95_RS17670 81b915b68d04275bd3eeaa8e7dfceefe 277 SUPERFAMILY SSF52540 3 256 3.42E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17670 81b915b68d04275bd3eeaa8e7dfceefe 277 Gene3D G3DSA:3.40.50.300 5 258 1.9E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17670 81b915b68d04275bd3eeaa8e7dfceefe 277 Pfam PF13469 Sulfotransferase family 5 201 7.8E-36 T 06-07-2017 CAK95_RS00200 f0363223a30291658d6fa69b8bcca51a 325 PIRSF PIRSF018005 6 325 1.8E-123 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAK95_RS00200 f0363223a30291658d6fa69b8bcca51a 325 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 23 321 5.5E-124 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAK95_RS00200 f0363223a30291658d6fa69b8bcca51a 325 SUPERFAMILY SSF53335 35 230 4.82E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00200 f0363223a30291658d6fa69b8bcca51a 325 SUPERFAMILY SSF53335 287 321 4.82E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00200 f0363223a30291658d6fa69b8bcca51a 325 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 197 320 1.3E-46 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 SMART SM00382 369 567 4.2E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 Gene3D G3DSA:3.40.50.300 342 587 1.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 Pfam PF00005 ABC transporter 360 518 8.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 SUPERFAMILY SSF52540 344 588 9.63E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 567 589 1.5E-11 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 299 8.8E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS14955 93f7bb2b1d51ed85dd2982b095eeddb7 592 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 Hamap MF_01576 Bifunctional protein FolD [folD]. 6 285 37.575 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 SUPERFAMILY SSF53223 5 124 1.63E-36 T 06-07-2017 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 Gene3D G3DSA:3.40.192.10 10 141 2.9E-45 T 06-07-2017 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 206 235 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 7.2E-83 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 262 270 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 Gene3D G3DSA:3.40.50.720 142 266 8.5E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 8 123 8.9E-37 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 SUPERFAMILY SSF51735 125 283 9.75E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28550 df410a87e798d8362c199ac7c69c3466 287 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 284 5.2E-69 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 SUPERFAMILY SSF46785 1 84 5.45E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 SUPERFAMILY SSF53850 88 299 7.06E-14 T 06-07-2017 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 Gene3D G3DSA:1.10.10.10 1 83 3.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 Gene3D G3DSA:3.40.190.10 176 264 3.2E-4 T 06-07-2017 CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 Pfam PF03466 LysR substrate binding domain 86 298 6.2E-15 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS09565 aae5c7cba1145423da01e0d439da26fa 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 177 192 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 355 371 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.4E-37 T 06-07-2017 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 SUPERFAMILY SSF51905 291 375 1.65E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 SUPERFAMILY SSF51905 9 198 1.65E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 Pfam PF01494 FAD binding domain 8 370 1.1E-72 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 Gene3D G3DSA:3.50.50.60 292 371 7.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 Gene3D G3DSA:3.50.50.60 118 203 7.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17835 6259e6e3ee776b433c0bbd78ddfeb061 557 Gene3D G3DSA:3.50.50.60 8 74 7.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS14520 696ab2c1e29efd602d1d2b4d7f560fa6 82 Gene3D G3DSA:3.90.1530.10 15 73 2.1E-12 T 06-07-2017 CAK95_RS14520 696ab2c1e29efd602d1d2b4d7f560fa6 82 SUPERFAMILY SSF110849 9 73 3.14E-15 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS14520 696ab2c1e29efd602d1d2b4d7f560fa6 82 SMART SM00470 2 81 0.0038 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS14520 696ab2c1e29efd602d1d2b4d7f560fa6 82 Pfam PF02195 ParB-like nuclease domain 15 73 3.5E-11 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK95_RS01170 e5b61cb362f1db4f84c4b5379e6e6857 454 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 400 9.6E-99 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS01170 e5b61cb362f1db4f84c4b5379e6e6857 454 SUPERFAMILY SSF50475 5 293 2.63E-73 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS01170 e5b61cb362f1db4f84c4b5379e6e6857 454 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 422 3.6E-89 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAK95_RS01170 e5b61cb362f1db4f84c4b5379e6e6857 454 SUPERFAMILY SSF143968 296 454 2.62E-28 T 06-07-2017 CAK95_RS01170 e5b61cb362f1db4f84c4b5379e6e6857 454 Gene3D G3DSA:3.40.1670.10 312 419 3.9E-21 T 06-07-2017 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 Gene3D G3DSA:2.60.410.10 313 403 6.5E-15 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 SMART SM00936 313 405 1.1E-22 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 153 170 4.1E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 95 106 4.1E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 180 193 4.1E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 Gene3D G3DSA:3.40.710.10 65 311 6.6E-87 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 SUPERFAMILY SSF56601 25 313 5.01E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 65 290 1.1E-68 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 SUPERFAMILY SSF69189 313 405 5.89E-16 T 06-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS23330 f9368d6b7d0e95de58741de2f7091670 431 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 313 403 8.6E-16 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK95_RS01845 ab44ea91c1240457c227c6b4e30ca181 292 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 10 282 4.7E-107 T 06-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAK95_RS01845 ab44ea91c1240457c227c6b4e30ca181 292 Pfam PF02219 Methylenetetrahydrofolate reductase 6 283 1.3E-95 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS01845 ab44ea91c1240457c227c6b4e30ca181 292 SUPERFAMILY SSF51730 5 286 5.89E-101 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS01845 ab44ea91c1240457c227c6b4e30ca181 292 Gene3D G3DSA:3.20.20.220 6 289 1.7E-105 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 Gene3D G3DSA:1.10.45.10 430 469 6.4E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 SUPERFAMILY SSF55103 202 471 3.43E-70 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 Pfam PF01565 FAD binding domain 54 192 2.0E-40 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 SUPERFAMILY SSF56176 17 229 2.9E-70 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 Gene3D G3DSA:3.30.465.10 109 229 1.8E-35 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 Gene3D G3DSA:3.30.43.10 11 107 2.7E-28 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS13720 9ae2577755ab1decff1d0527e32d105d 497 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 469 1.7E-64 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK95_RS02185 942a2a521f40474e541813d842450da5 309 SUPERFAMILY SSF53850 97 260 1.96E-11 T 06-07-2017 CAK95_RS02185 942a2a521f40474e541813d842450da5 309 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 33 303 1.9E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02185 942a2a521f40474e541813d842450da5 309 PIRSF PIRSF017082 1 308 3.2E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27000 a5a036082192b38529db61fabb8d2d18 432 PIRSF PIRSF006066 2 432 2.7E-99 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS27000 a5a036082192b38529db61fabb8d2d18 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 423 7.8E-95 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS27000 a5a036082192b38529db61fabb8d2d18 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 19 428 2.6E-99 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS26645 900e99917d96fcdc992a582c4a593f12 166 SUPERFAMILY SSF55154 1 149 2.13E-40 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CAK95_RS26645 900e99917d96fcdc992a582c4a593f12 166 Gene3D G3DSA:2.40.320.10 1 152 1.1E-52 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK95_RS26645 900e99917d96fcdc992a582c4a593f12 166 PIRSF PIRSF016487 1 159 1.8E-58 T 06-07-2017 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like CAK95_RS26645 900e99917d96fcdc992a582c4a593f12 166 SMART SM01118 2 152 2.4E-17 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK95_RS26645 900e99917d96fcdc992a582c4a593f12 166 Pfam PF01928 CYTH domain 4 141 1.6E-10 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK95_RS02855 57d4a5968f219296c4a545d9b4ced6e2 446 SUPERFAMILY SSF103473 23 443 4.05E-25 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS02855 57d4a5968f219296c4a545d9b4ced6e2 446 Gene3D G3DSA:1.20.1250.20 21 220 1.0E-8 T 06-07-2017 CAK95_RS02855 57d4a5968f219296c4a545d9b4ced6e2 446 Gene3D G3DSA:1.20.1250.20 254 444 9.8E-12 T 06-07-2017 CAK95_RS02855 57d4a5968f219296c4a545d9b4ced6e2 446 Pfam PF07690 Major Facilitator Superfamily 28 334 1.4E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS13040 a8f95cfff705568691d268673eafd189 410 SUPERFAMILY SSF56801 103 379 4.06E-32 T 06-07-2017 CAK95_RS13040 a8f95cfff705568691d268673eafd189 410 Pfam PF00501 AMP-binding enzyme 135 275 9.3E-14 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS13040 a8f95cfff705568691d268673eafd189 410 Gene3D G3DSA:3.30.300.30 313 399 5.7E-12 T 06-07-2017 CAK95_RS13040 a8f95cfff705568691d268673eafd189 410 Gene3D G3DSA:3.40.50.980 115 240 2.8E-11 T 06-07-2017 CAK95_RS07605 153b05bc9ac9e4d4982a99a1c4fd1e16 262 SUPERFAMILY SSF55120 3 229 1.26E-58 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS07605 153b05bc9ac9e4d4982a99a1c4fd1e16 262 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 61 75 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS07605 153b05bc9ac9e4d4982a99a1c4fd1e16 262 Pfam PF00849 RNA pseudouridylate synthase 18 170 1.5E-33 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 Gene3D G3DSA:3.40.190.10 94 175 1.2E-11 T 06-07-2017 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 Pfam PF03466 LysR substrate binding domain 93 294 1.8E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 Gene3D G3DSA:1.10.10.10 4 85 7.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 SUPERFAMILY SSF53850 96 297 1.29E-36 T 06-07-2017 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 Gene3D G3DSA:3.40.190.10 176 263 1.7E-25 T 06-07-2017 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 SUPERFAMILY SSF46785 4 83 1.19E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02140 8aed21fdee73416ef47861f8c37b4ba3 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 6.6E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 6.2E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 SMART SM00448 4 115 3.8E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 Pfam PF00072 Response regulator receiver domain 6 116 3.5E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 Gene3D G3DSA:1.10.10.10 133 233 1.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 SUPERFAMILY SSF46894 127 230 4.25E-25 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 SUPERFAMILY SSF52172 2 126 1.24E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 Gene3D G3DSA:3.40.50.2300 3 127 2.3E-40 T 06-07-2017 CAK95_RS01270 5d15eba4d44760facc22ad07e55be209 240 SMART SM00862 154 229 1.7E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS22335 a21fb2effc5a125160948527755df8cd 257 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 15 251 2.9E-95 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAK95_RS22335 a21fb2effc5a125160948527755df8cd 257 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 256 116.052 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAK95_RS22335 a21fb2effc5a125160948527755df8cd 257 Gene3D G3DSA:3.20.20.70 14 253 1.1E-99 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS22335 a21fb2effc5a125160948527755df8cd 257 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 15 251 1.8E-82 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAK95_RS22335 a21fb2effc5a125160948527755df8cd 257 SUPERFAMILY SSF63892 14 254 1.24E-91 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAK95_RS20515 76c5373267c5e4c84fa01da3496bf0e0 348 Pfam PF14525 AraC-binding-like domain 38 218 2.0E-35 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS20515 76c5373267c5e4c84fa01da3496bf0e0 348 Gene3D G3DSA:1.10.10.60 235 292 5.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20515 76c5373267c5e4c84fa01da3496bf0e0 348 Pfam PF12833 Helix-turn-helix domain 261 342 1.6E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS20515 76c5373267c5e4c84fa01da3496bf0e0 348 SUPERFAMILY SSF46689 240 286 2.51E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS20515 76c5373267c5e4c84fa01da3496bf0e0 348 SMART SM00342 255 340 1.3E-9 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 Gene3D G3DSA:3.40.190.10 94 173 6.9E-22 T 06-07-2017 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 Pfam PF03466 LysR substrate binding domain 92 291 2.1E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 Gene3D G3DSA:1.10.10.10 2 86 3.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 9.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 9.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 9.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 1.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 SUPERFAMILY SSF53850 92 292 1.09E-29 T 06-07-2017 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 Gene3D G3DSA:3.40.190.10 174 257 1.2E-16 T 06-07-2017 CAK95_RS26090 50e056bb64bc7fa0fbdc639b02f0a367 303 SUPERFAMILY SSF46785 4 86 2.45E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00855 5a2929013efb50b576e5222e5d42e77b 151 SUPERFAMILY SSF51182 49 140 2.83E-9 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS00855 5a2929013efb50b576e5222e5d42e77b 151 Gene3D G3DSA:2.60.120.10 37 136 2.7E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 SUPERFAMILY SSF52518 20 209 5.89E-27 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 351 1.7E-9 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 23 202 3.4E-26 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Gene3D G3DSA:3.40.50.1220 218 378 6.3E-17 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Gene3D G3DSA:3.40.50.970 24 208 1.7E-27 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 SUPERFAMILY SSF52467 219 365 4.78E-18 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 SUPERFAMILY SSF52518 401 580 1.79E-27 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 429 564 2.5E-15 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS02235 e7a5a76bb6a45652588538aafe206824 589 Gene3D G3DSA:3.40.50.970 391 580 8.4E-29 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 Gene3D G3DSA:1.10.3810.10 106 273 8.8E-68 T 06-07-2017 CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 Gene3D G3DSA:3.40.710.10 274 650 4.4E-106 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 SUPERFAMILY SSF56601 255 277 1.48E-107 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 SUPERFAMILY SSF56601 304 658 1.48E-107 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 Pfam PF00905 Penicillin binding protein transpeptidase domain 366 637 6.2E-25 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 SUPERFAMILY SSF53955 90 294 9.84E-70 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 Pfam PF00912 Transglycosylase 109 273 4.1E-60 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK95_RS18895 910c92cb855867465a9e4fc6dcfee13d 736 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 112 642 3.5E-170 T 06-07-2017 CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 Pfam PF00106 short chain dehydrogenase 4 196 1.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 SUPERFAMILY SSF51735 2 227 2.73E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 Gene3D G3DSA:3.40.50.720 2 230 4.7E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20600 7e58b51561d2d571db8797ddab9e1a5f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 10 176 1.8E-63 T 06-07-2017 IPR010195 Uncharacterised peroxidase-related CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 Gene3D G3DSA:1.20.5.810 11 59 4.3E-21 T 06-07-2017 CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 Gene3D G3DSA:1.20.1290.10 60 180 2.8E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 SUPERFAMILY SSF69118 8 181 1.57E-52 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 92 1.9E-9 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS08500 57a2cc2b160a6c497c8a2f71a46dfee9 184 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 107 6.4E-12 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 Gene3D G3DSA:3.40.190.10 128 220 5.5E-5 T 06-07-2017 CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 SUPERFAMILY SSF53850 41 264 1.16E-29 T 06-07-2017 CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 260 1.3E-22 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 Gene3D G3DSA:3.40.190.10 47 127 6.6E-12 T 06-07-2017 CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 Gene3D G3DSA:3.40.190.10 228 263 6.6E-12 T 06-07-2017 CAK95_RS08230 41be8efcf1e91008473f544c1665b200 279 SMART SM00062 47 265 2.3E-16 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 1 12 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 311 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 139 154 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 260 275 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 291 6.0E-25 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 Gene3D G3DSA:3.30.9.10 308 336 5.2E-12 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 Gene3D G3DSA:3.30.9.10 152 253 5.2E-12 T 06-07-2017 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 Gene3D G3DSA:3.50.50.60 258 298 1.2E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 Gene3D G3DSA:3.50.50.60 10 151 1.2E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 SUPERFAMILY SSF51905 4 160 4.54E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 SUPERFAMILY SSF51905 247 361 4.54E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01450 673654a64391f6350e81f14ca06175ea 537 Pfam PF01494 FAD binding domain 1 324 1.5E-60 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 205 2.1E-71 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 Gene3D G3DSA:3.20.20.70 3 207 9.3E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 38 47 - T 06-07-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 126 139 - T 06-07-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 Pfam PF01081 KDPG and KHG aldolase 6 201 4.1E-66 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAK95_RS12860 de7403d97539e21522712836991f1c62 210 SUPERFAMILY SSF51569 5 207 8.79E-64 T 06-07-2017 CAK95_RS20370 66214615a38d9d38e8cd3883135f7b8a 215 SUPERFAMILY SSF53474 22 186 1.56E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20370 66214615a38d9d38e8cd3883135f7b8a 215 Gene3D G3DSA:3.40.50.1820 57 100 7.3E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20370 66214615a38d9d38e8cd3883135f7b8a 215 SUPERFAMILY SSF53474 70 124 5.62E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 Gene3D G3DSA:1.10.287.990 20 85 6.0E-23 T 06-07-2017 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 193 5.5E-34 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 SUPERFAMILY SSF46609 1 86 7.07E-34 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.4E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 2.4E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PRINTS PR01703 Manganese superoxide dismutase signature 68 81 2.4E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.4E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PRINTS PR01703 Manganese superoxide dismutase signature 122 130 2.4E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 SUPERFAMILY SSF54719 88 198 4.06E-40 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 85 2.3E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS18800 085c5b840e17d7178cda126fac22c7af 200 PIRSF PIRSF000349 1 200 2.1E-78 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 Pfam PF12840 Helix-turn-helix domain 10 69 2.0E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 SMART SM00418 8 88 1.6E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 Gene3D G3DSA:1.10.10.10 2 100 4.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09695 79005a0fab03b0f92846befca0a63857 126 SUPERFAMILY SSF46785 2 93 5.55E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 630 641 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Gene3D G3DSA:3.30.465.10 97 265 4.5E-39 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 SUPERFAMILY SSF46548 568 649 1.15E-9 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 SUPERFAMILY SSF56176 8 264 6.18E-61 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Gene3D G3DSA:1.10.1060.10 502 653 2.9E-13 T 06-07-2017 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Pfam PF13183 4Fe-4S dicluster domain 567 644 1.5E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 SUPERFAMILY SSF55103 269 528 1.44E-50 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Gene3D G3DSA:3.30.43.10 12 96 8.8E-16 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Pfam PF01565 FAD binding domain 42 179 2.9E-38 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS09760 cb655edcdcec17fa830bc43dfdceefa2 1002 Pfam PF02913 FAD linked oxidases, C-terminal domain 269 524 1.6E-45 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK95_RS05115 c6ce2371468e8cee7624f58b6b0e9042 484 SUPERFAMILY SSF56925 41 221 3.66E-27 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS05115 c6ce2371468e8cee7624f58b6b0e9042 484 Gene3D G3DSA:2.40.160.20 37 230 3.2E-34 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS05115 c6ce2371468e8cee7624f58b6b0e9042 484 Pfam PF13505 Outer membrane protein beta-barrel domain 22 221 7.7E-19 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS11825 167fed014223fc92e5511b961ee844d3 221 Pfam PF02230 Phospholipase/Carboxylesterase 8 216 2.1E-34 T 06-07-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CAK95_RS11825 167fed014223fc92e5511b961ee844d3 221 SUPERFAMILY SSF53474 10 218 4.84E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS11825 167fed014223fc92e5511b961ee844d3 221 Gene3D G3DSA:3.40.50.1820 10 218 1.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16635 5ff54b61bac8a8ec5f73e1dfd0958844 326 Gene3D G3DSA:3.40.190.10 117 248 4.0E-11 T 06-07-2017 CAK95_RS16635 5ff54b61bac8a8ec5f73e1dfd0958844 326 SUPERFAMILY SSF53850 28 265 1.0E-26 T 06-07-2017 CAK95_RS16635 5ff54b61bac8a8ec5f73e1dfd0958844 326 Pfam PF13379 NMT1-like family 27 269 4.2E-15 T 06-07-2017 CAK95_RS10015 9c8be84aeeb17b475e1e5d71761eccb8 394 Pfam PF13458 Periplasmic binding protein 27 372 3.0E-66 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS10015 9c8be84aeeb17b475e1e5d71761eccb8 394 SUPERFAMILY SSF53822 27 383 1.85E-79 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS10015 9c8be84aeeb17b475e1e5d71761eccb8 394 Gene3D G3DSA:3.40.50.2300 23 149 1.0E-36 T 06-07-2017 CAK95_RS10015 9c8be84aeeb17b475e1e5d71761eccb8 394 Gene3D G3DSA:3.40.50.2300 304 355 1.0E-36 T 06-07-2017 CAK95_RS10015 9c8be84aeeb17b475e1e5d71761eccb8 394 Gene3D G3DSA:3.40.50.2300 150 303 6.4E-21 T 06-07-2017 CAK95_RS27545 e2a479d95c2b4df3f2e47df41cbf7e84 334 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 45 308 2.6E-27 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS11315 5b5703f456033714d18f97a0a13bbf8b 153 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 11 142 1.8E-14 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS11315 5b5703f456033714d18f97a0a13bbf8b 153 SMART SM00226 9 147 1.8E-22 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS11315 5b5703f456033714d18f97a0a13bbf8b 153 SUPERFAMILY SSF52788 9 145 3.14E-34 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK95_RS11315 5b5703f456033714d18f97a0a13bbf8b 153 Gene3D G3DSA:3.40.50.270 7 145 1.3E-30 T 06-07-2017 CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 Pfam PF07729 FCD domain 125 248 1.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 SMART SM00895 125 249 1.9E-12 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 SUPERFAMILY SSF46785 47 119 1.36E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 SUPERFAMILY SSF48008 121 251 2.3E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 Gene3D G3DSA:1.10.10.10 37 111 1.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 Gene3D G3DSA:1.20.120.530 119 252 8.5E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 SMART SM00345 58 114 1.7E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS27395 3df80548b9017124114a87e7dcae968a 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 55 111 1.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS02350 02c1433612e379a3b1331d44188f7474 89 PIRSF PIRSF017854 5 89 7.2E-34 T 06-07-2017 IPR016704 Conjugal transfer, TrbD CAK95_RS02350 02c1433612e379a3b1331d44188f7474 89 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 12 83 4.8E-11 T 06-07-2017 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB CAK95_RS07755 66b0408ecb10fae37cca70859cfd6e8f 252 Gene3D G3DSA:1.10.10.10 5 99 8.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07755 66b0408ecb10fae37cca70859cfd6e8f 252 Pfam PF01638 HxlR-like helix-turn-helix 18 102 1.7E-17 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS07755 66b0408ecb10fae37cca70859cfd6e8f 252 SUPERFAMILY SSF46785 5 107 1.69E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07755 66b0408ecb10fae37cca70859cfd6e8f 252 SUPERFAMILY SSF55718 114 220 1.88E-5 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 Gene3D G3DSA:2.60.120.600 301 481 1.2E-58 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 Pfam PF06742 Protein of unknown function (DUF1214) 347 458 1.9E-37 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 Gene3D G3DSA:1.10.3360.10 212 275 1.1E-4 T 06-07-2017 IPR023289 VPA0735-like domain CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 SUPERFAMILY SSF160935 21 480 1.28E-123 T 06-07-2017 CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 Gene3D G3DSA:2.60.40.1610 91 211 1.8E-21 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS03495 280ed1949d2f94ac4de206d22478bd15 481 Pfam PF06863 Protein of unknown function (DUF1254) 78 209 2.6E-40 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS19375 b7af87c616e78c38799f9d80ceeb868a 1448 Gene3D G3DSA:3.40.50.300 420 472 3.5E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19375 b7af87c616e78c38799f9d80ceeb868a 1448 Gene3D G3DSA:3.40.1140.10 1330 1347 8.3E-4 T 06-07-2017 CAK95_RS19375 b7af87c616e78c38799f9d80ceeb868a 1448 Gene3D G3DSA:3.40.1140.10 36 101 8.3E-4 T 06-07-2017 CAK95_RS15610 54281f21d0f1fd951c230b7b662aa828 257 SMART SM00382 28 228 3.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15610 54281f21d0f1fd951c230b7b662aa828 257 Pfam PF00005 ABC transporter 20 179 1.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15610 54281f21d0f1fd951c230b7b662aa828 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 1.0E-12 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS15610 54281f21d0f1fd951c230b7b662aa828 257 Gene3D G3DSA:3.40.50.300 3 249 2.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15610 54281f21d0f1fd951c230b7b662aa828 257 SUPERFAMILY SSF52540 4 250 2.72E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 Gene3D G3DSA:1.10.10.10 96 161 2.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 158 3.9E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 SUPERFAMILY SSF88946 5 84 1.18E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 SUPERFAMILY SSF88659 79 160 2.8E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 Pfam PF04545 Sigma-70, region 4 111 155 4.6E-6 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 Gene3D G3DSA:1.10.1740.10 5 93 1.1E-12 T 06-07-2017 CAK95_RS05230 50399fc68ceab53bed6b8a241776a65c 164 Pfam PF04542 Sigma-70 region 2 7 72 1.1E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07865 1d851abbb70a3f4bf59e3fbc76df6e06 254 SUPERFAMILY SSF51120 146 239 4.58E-7 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS07865 1d851abbb70a3f4bf59e3fbc76df6e06 254 SUPERFAMILY SSF54621 9 118 5.23E-6 T 06-07-2017 IPR010495 Haem-binding HasA CAK95_RS07865 1d851abbb70a3f4bf59e3fbc76df6e06 254 Gene3D G3DSA:2.150.10.10 145 234 3.2E-5 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS17365 ebf54837fd8009ce25bec55b268eb27a 333 SUPERFAMILY SSF47240 43 286 4.06E-83 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS17365 ebf54837fd8009ce25bec55b268eb27a 333 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 23 312 3.0E-161 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CAK95_RS17365 ebf54837fd8009ce25bec55b268eb27a 333 Gene3D G3DSA:1.20.1260.10 33 288 5.2E-103 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS17365 ebf54837fd8009ce25bec55b268eb27a 333 Pfam PF05138 Phenylacetic acid catabolic protein 33 308 1.8E-102 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 Gene3D G3DSA:3.90.226.10 186 220 2.6E-18 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 Gene3D G3DSA:3.90.226.10 33 137 2.6E-18 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 Gene3D G3DSA:2.40.50.140 394 449 2.5E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 SUPERFAMILY SSF141322 385 448 2.35E-10 T 06-07-2017 CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 SUPERFAMILY SSF52096 20 210 1.99E-24 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS25280 0b444b421d0f9b298b85535935699774 450 Pfam PF01957 NfeD-like C-terminal, partner-binding 312 449 2.1E-30 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain CAK95_RS18890 4477249aee655ab6b2e51457a077e49a 192 SUPERFAMILY SSF160935 23 167 1.57E-24 T 06-07-2017 CAK95_RS18890 4477249aee655ab6b2e51457a077e49a 192 Gene3D G3DSA:2.60.120.600 27 186 7.0E-26 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS18890 4477249aee655ab6b2e51457a077e49a 192 Pfam PF06742 Protein of unknown function (DUF1214) 72 169 2.3E-19 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS18890 4477249aee655ab6b2e51457a077e49a 192 PIRSF PIRSF009471 1 192 3.5E-63 T 06-07-2017 IPR012038 Uncharacterised conserved protein UCP009471 CAK95_RS25120 0f8ce7e2bfb26a81b50ad83a511c8578 86 SUPERFAMILY SSF141371 12 85 2.94E-7 T 06-07-2017 CAK95_RS25120 0f8ce7e2bfb26a81b50ad83a511c8578 86 Pfam PF07238 PilZ domain 15 85 2.1E-5 T 06-07-2017 IPR009875 PilZ domain GO:0035438 CAK95_RS27735 5bf38a18012936c74a51f6513a45ed1f 259 Gene3D G3DSA:3.90.226.10 4 202 2.1E-47 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS27735 5bf38a18012936c74a51f6513a45ed1f 259 SUPERFAMILY SSF52096 3 258 1.41E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS27735 5bf38a18012936c74a51f6513a45ed1f 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 4.2E-39 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS27735 5bf38a18012936c74a51f6513a45ed1f 259 Gene3D G3DSA:1.10.12.10 203 258 3.3E-12 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS08980 021a94b4549ff49ef3eb70d9e9c1fe79 276 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 38 140 7.9E-11 T 06-07-2017 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CAK95_RS08980 021a94b4549ff49ef3eb70d9e9c1fe79 276 Gene3D G3DSA:2.30.30.330 37 231 1.6E-21 T 06-07-2017 CAK95_RS08980 021a94b4549ff49ef3eb70d9e9c1fe79 276 SUPERFAMILY SSF54001 37 232 4.32E-24 T 06-07-2017 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 SUPERFAMILY SSF55681 104 345 4.27E-79 T 06-07-2017 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 343 7.1E-100 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 Pfam PF01409 tRNA synthetases class II core domain (F) 92 343 3.5E-103 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 3.5E-20 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 344 45.416 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 SUPERFAMILY SSF46589 12 99 1.88E-17 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK95_RS09025 16415094d7d0c9ed6303465f9f72e971 360 Gene3D G3DSA:3.30.930.10 9 344 2.0E-124 T 06-07-2017 CAK95_RS24855 9ca8cc7d41e55ad1490435de70e988af 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 424 1.5E-109 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS24855 9ca8cc7d41e55ad1490435de70e988af 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 419 6.1E-97 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS24855 9ca8cc7d41e55ad1490435de70e988af 430 PIRSF PIRSF006066 3 430 1.7E-117 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS13340 a5015c39e74b1d7917ea4ceb9bb0a517 139 Pfam PF00472 RF-1 domain 6 133 1.8E-26 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS13340 a5015c39e74b1d7917ea4ceb9bb0a517 139 SUPERFAMILY SSF75620 7 135 2.67E-14 T 06-07-2017 CAK95_RS13340 a5015c39e74b1d7917ea4ceb9bb0a517 139 Gene3D G3DSA:3.30.160.200 2 108 8.0E-33 T 06-07-2017 CAK95_RS13340 a5015c39e74b1d7917ea4ceb9bb0a517 139 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK95_RS05725 8e93290c268eea61f670d091d86d5413 216 Pfam PF06823 Protein of unknown function (DUF1236) 156 215 7.0E-20 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS05725 8e93290c268eea61f670d091d86d5413 216 Pfam PF08239 Bacterial SH3 domain 30 81 1.2E-10 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type CAK95_RS04685 cda3bc4b62cda0f51cb9a094bbc7df63 135 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 17.422 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK95_RS04685 cda3bc4b62cda0f51cb9a094bbc7df63 135 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 7 91 1.2E-15 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CAK95_RS04685 cda3bc4b62cda0f51cb9a094bbc7df63 135 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 88 2.4E-23 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK95_RS04685 cda3bc4b62cda0f51cb9a094bbc7df63 135 SUPERFAMILY SSF101386 5 92 1.1E-18 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 SUPERFAMILY SSF111369 80 131 1.96E-5 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 Gene3D G3DSA:2.40.50.100 301 335 3.9E-16 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 Gene3D G3DSA:2.40.50.100 74 105 3.9E-16 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 Pfam PF13437 HlyD family secretion protein 304 416 2.8E-15 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 Pfam PF13533 Biotin-lipoyl like 78 119 5.2E-7 T 06-07-2017 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 37 454 1.6E-114 T 06-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 433 453 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 41 64 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 316 337 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 83 103 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 418 433 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 349 373 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS21060 f07373fabeb9f60947f1cd9aae01edc4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 373 396 2.1E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAK95_RS17095 cb51591e29948741b7a555f8b77a98f4 457 Gene3D G3DSA:3.30.1330.120 262 395 2.5E-18 T 06-07-2017 CAK95_RS17095 cb51591e29948741b7a555f8b77a98f4 457 Pfam PF03972 MmgE/PrpD family 5 435 1.5E-89 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS17095 cb51591e29948741b7a555f8b77a98f4 457 SUPERFAMILY SSF103378 1 442 7.59E-93 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS12390 133c71b5c7a3a1194f12eebb4a62f0ce 269 SUPERFAMILY SSF53474 12 267 1.52E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12390 133c71b5c7a3a1194f12eebb4a62f0ce 269 Gene3D G3DSA:3.40.50.1820 12 267 1.4E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12390 133c71b5c7a3a1194f12eebb4a62f0ce 269 Pfam PF12697 Alpha/beta hydrolase family 31 257 1.1E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS19310 bf4dbe5811fe88ce7161823f96174e17 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 280 2.3E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 162 171 - T 06-07-2017 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 Gene3D G3DSA:3.20.20.80 27 268 4.4E-46 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 Gene3D G3DSA:3.20.20.80 307 386 4.4E-46 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 SUPERFAMILY SSF51445 50 248 6.28E-39 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 SUPERFAMILY SSF51445 307 386 6.28E-39 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS27445 4e9b75f96da3f0224b3747aa7e6db43a 412 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 65 379 1.5E-31 T 06-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAK95_RS00345 b912b1112e92af196c00c5de3689cd4b 294 SUPERFAMILY SSF54593 1 245 3.63E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00345 b912b1112e92af196c00c5de3689cd4b 294 Gene3D G3DSA:3.10.180.10 2 127 1.4E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00345 b912b1112e92af196c00c5de3689cd4b 294 Gene3D G3DSA:3.10.180.10 133 275 2.0E-41 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00345 b912b1112e92af196c00c5de3689cd4b 294 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 134 243 3.2E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS00345 b912b1112e92af196c00c5de3689cd4b 294 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 113 6.9E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS17920 5db0e85e50b9443b3c1bd8fdab16ecaf 306 Pfam PF02470 MlaD protein 49 114 2.4E-13 T 06-07-2017 IPR003399 Mce/MlaD CAK95_RS04655 6033945b64c0ed35114e2f5ea6680077 122 Gene3D G3DSA:3.40.50.2300 3 121 2.2E-42 T 06-07-2017 CAK95_RS04655 6033945b64c0ed35114e2f5ea6680077 122 Pfam PF00072 Response regulator receiver domain 5 116 1.7E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04655 6033945b64c0ed35114e2f5ea6680077 122 SMART SM00448 3 116 5.6E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS04655 6033945b64c0ed35114e2f5ea6680077 122 SUPERFAMILY SSF52172 3 120 2.85E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS14085 4e8f06831df792b1fd4f0ec676b651de 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 126 3.2E-16 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK95_RS14085 4e8f06831df792b1fd4f0ec676b651de 296 SUPERFAMILY SSF111331 3 293 1.26E-45 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK95_RS14085 4e8f06831df792b1fd4f0ec676b651de 296 Gene3D G3DSA:3.40.50.10330 53 134 3.3E-4 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK95_RS14085 4e8f06831df792b1fd4f0ec676b651de 296 SMART SM00046 3 127 0.0049 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 227 472 6.6E-50 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Gene3D G3DSA:3.40.50.10260 1 224 3.1E-65 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Pfam PF03853 YjeF-related protein N-terminus 26 181 2.0E-37 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Gene3D G3DSA:3.40.1190.20 225 492 5.0E-77 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 PIRSF PIRSF017184 2 495 2.0E-109 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 SUPERFAMILY SSF64153 3 239 9.81E-60 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 434 444 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 202 25.155 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 5 203 3.7E-42 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 217 490 18.122 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 SUPERFAMILY SSF53613 215 492 9.04E-62 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS22685 6438d46ef881a8099a546370ca5d3cc4 501 Pfam PF01256 Carbohydrate kinase 241 471 4.2E-49 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 Gene3D G3DSA:1.10.630.10 8 395 1.5E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 87 98 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 270 281 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 287 314 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 345 356 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 315 330 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 336 345 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 150 165 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 PRINTS PR00359 B-class P450 signature 133 149 8.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 Pfam PF00067 Cytochrome P450 264 365 3.6E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS08720 557749375cef72e7e48671b70fd9713b 408 SUPERFAMILY SSF48264 13 394 4.45E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 SUPERFAMILY SSF48498 136 248 2.46E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 89 112 1.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 81 1.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 Gene3D G3DSA:1.10.357.10 111 249 9.4E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 Gene3D G3DSA:1.10.10.60 62 110 8.3E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 SUPERFAMILY SSF46689 56 119 1.4E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS01040 ddc600cb8b1f4c7330df610f93fa0d4b 279 Pfam PF00440 Bacterial regulatory proteins, tetR family 69 114 1.8E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS18325 a3dac59e933bea177965ef75b785897a 187 SUPERFAMILY SSF52540 6 175 5.94E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18325 a3dac59e933bea177965ef75b785897a 187 Pfam PF13521 AAA domain 8 171 1.1E-45 T 06-07-2017 CAK95_RS18325 a3dac59e933bea177965ef75b785897a 187 Gene3D G3DSA:3.40.50.300 9 176 8.6E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19460 b47ef8fec052b4c1869a7a3b3bae96ca 311 Pfam PF10686 Protein of unknown function (DUF2493) 194 260 6.5E-30 T 06-07-2017 IPR019627 Mycobacteriophage D29, Gp61 CAK95_RS27275 296c1722d46e356a10354c6ef33cc8fb 305 SMART SM00849 72 283 1.7E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS27275 296c1722d46e356a10354c6ef33cc8fb 305 Pfam PF00753 Metallo-beta-lactamase superfamily 74 276 1.2E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS27275 296c1722d46e356a10354c6ef33cc8fb 305 SUPERFAMILY SSF56281 71 297 4.06E-34 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS27275 296c1722d46e356a10354c6ef33cc8fb 305 Gene3D G3DSA:3.60.15.10 56 299 3.3E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS14540 ecdab157dfd7e6f13403f486d19052b8 183 Pfam PF13279 Thioesterase-like superfamily 22 127 2.5E-13 T 06-07-2017 CAK95_RS14540 ecdab157dfd7e6f13403f486d19052b8 183 SUPERFAMILY SSF54637 16 92 1.07E-21 T 06-07-2017 IPR029069 HotDog domain CAK95_RS14540 ecdab157dfd7e6f13403f486d19052b8 183 Gene3D G3DSA:3.10.129.10 14 92 2.0E-25 T 06-07-2017 IPR029069 HotDog domain CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 269 288 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 PIRSF PIRSF000108 1 403 8.9E-222 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 SUPERFAMILY SSF53659 1 402 3.46E-149 T 06-07-2017 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 SMART SM01329 9 394 2.1E-122 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 402 3.3E-206 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 394 9.2E-70 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS26575 a741b8dfd98e4d7f1903a388d2731e77 403 Gene3D G3DSA:3.40.718.10 3 402 1.5E-171 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS02330 a53bcf1ae5d8fcb55cb866a7145840ba 449 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 254 1.2E-55 T 06-07-2017 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 CAK95_RS02330 a53bcf1ae5d8fcb55cb866a7145840ba 449 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 3 308 7.3E-59 T 06-07-2017 IPR014150 Conjugal transfer, TrbL CAK95_RS08630 f411ffafa574448b8925fcf9fb91a8d8 171 Pfam PF06078 Bacterial protein of unknown function (DUF937) 66 165 3.4E-12 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS08630 f411ffafa574448b8925fcf9fb91a8d8 171 SUPERFAMILY SSF140804 70 169 2.62E-28 T 06-07-2017 IPR027405 YidB-like CAK95_RS08630 f411ffafa574448b8925fcf9fb91a8d8 171 Gene3D G3DSA:1.10.10.690 63 170 8.4E-29 T 06-07-2017 IPR027405 YidB-like CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Gene3D G3DSA:1.10.530.10 170 232 1.8E-4 T 06-07-2017 CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 SUPERFAMILY SSF53955 26 333 4.5E-80 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Gene3D G3DSA:1.10.101.10 349 407 1.5E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Pfam PF01471 Putative peptidoglycan binding domain 349 404 8.6E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 SUPERFAMILY SSF47090 338 406 7.65E-14 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Gene3D G3DSA:1.10.530.10 233 332 4.2E-40 T 06-07-2017 CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Gene3D G3DSA:1.10.530.10 82 139 4.2E-40 T 06-07-2017 CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 39 330 3.2E-92 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS24720 cd3ec1c49ca0109ac345a560a394fc93 408 Pfam PF13406 Transglycosylase SLT domain 39 327 2.9E-81 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS06855 b82906b8fafb95e5a306585452186057 133 Pfam PF03610 PTS system fructose IIA component 3 114 4.3E-29 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAK95_RS06855 b82906b8fafb95e5a306585452186057 133 SUPERFAMILY SSF53062 1 128 7.98E-38 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAK95_RS06855 b82906b8fafb95e5a306585452186057 133 Gene3D G3DSA:3.40.50.510 1 128 1.6E-41 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 14 406 9.9E-153 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 Pfam PF00202 Aminotransferase class-III 22 406 4.1E-114 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 SUPERFAMILY SSF53383 22 408 7.13E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 Gene3D G3DSA:3.40.640.10 67 314 1.9E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 Gene3D G3DSA:3.90.1150.10 316 408 8.1E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 Gene3D G3DSA:3.90.1150.10 16 66 8.1E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 20 407 37.269 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAK95_RS21485 6aaa15ff06c2ef3202995243762e0f38 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 268 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Gene3D G3DSA:3.40.50.980 17 203 3.1E-31 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Pfam PF00501 AMP-binding enzyme 24 484 5.3E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Gene3D G3DSA:3.40.50.980 204 298 1.1E-27 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Gene3D G3DSA:3.40.50.980 351 406 1.1E-27 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Gene3D G3DSA:2.30.38.10 422 478 9.5E-16 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 SUPERFAMILY SSF56801 10 303 4.32E-107 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 SUPERFAMILY SSF56801 354 618 4.32E-107 T 06-07-2017 CAK95_RS16025 28185c37ca842f7785fc217217a213d4 633 Gene3D G3DSA:3.30.300.30 480 604 1.2E-5 T 06-07-2017 CAK95_RS07740 3d96ad50f3d747333a7626da92d1ceba 223 Pfam PF00484 Carbonic anhydrase 39 195 2.8E-46 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS07740 3d96ad50f3d747333a7626da92d1ceba 223 SUPERFAMILY SSF53056 2 212 2.22E-59 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS07740 3d96ad50f3d747333a7626da92d1ceba 223 SMART SM00947 31 200 3.2E-64 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS07740 3d96ad50f3d747333a7626da92d1ceba 223 Gene3D G3DSA:3.40.1050.10 2 209 1.8E-63 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK95_RS11115 1137a50edc0ba9cd3379a3e542805d40 186 Gene3D G3DSA:1.20.1440.20 14 186 1.2E-66 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS11115 1137a50edc0ba9cd3379a3e542805d40 186 Pfam PF04011 LemA family 6 186 1.1E-68 T 06-07-2017 IPR007156 LemA CAK95_RS11115 1137a50edc0ba9cd3379a3e542805d40 186 SUPERFAMILY SSF140478 25 172 4.58E-56 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS24970 4d4538e3392ffd2588753e4db97b5f89 127 Gene3D G3DSA:2.60.300.12 10 105 4.3E-35 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS24970 4d4538e3392ffd2588753e4db97b5f89 127 Pfam PF01521 Iron-sulphur cluster biosynthesis 11 112 9.7E-21 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS24970 4d4538e3392ffd2588753e4db97b5f89 127 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 12 115 4.7E-36 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAK95_RS24970 4d4538e3392ffd2588753e4db97b5f89 127 SUPERFAMILY SSF89360 6 102 2.35E-29 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK95_RS23430 4c9cd1885eb9fed2f55854dd0a83cbac 100 Gene3D G3DSA:3.40.30.10 13 98 8.2E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23430 4c9cd1885eb9fed2f55854dd0a83cbac 100 SUPERFAMILY SSF52833 12 98 5.96E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS28800 c3d012075081536c40ac91c4d7e069a7 214 Gene3D G3DSA:3.40.50.360 15 195 6.0E-37 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS28800 c3d012075081536c40ac91c4d7e069a7 214 Pfam PF03358 NADPH-dependent FMN reductase 17 156 3.1E-21 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS28800 c3d012075081536c40ac91c4d7e069a7 214 SUPERFAMILY SSF52218 17 192 7.11E-28 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS06040 d5c9b2cf3476d8af72ef39bfc94c2ced 129 Pfam PF00072 Response regulator receiver domain 9 121 1.4E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06040 d5c9b2cf3476d8af72ef39bfc94c2ced 129 SUPERFAMILY SSF52172 7 126 2.85E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06040 d5c9b2cf3476d8af72ef39bfc94c2ced 129 Gene3D G3DSA:3.40.50.2300 6 127 2.6E-34 T 06-07-2017 CAK95_RS06040 d5c9b2cf3476d8af72ef39bfc94c2ced 129 SMART SM00448 7 121 1.8E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS10620 7aeab08fe5c4565b2afc71e797c45ed9 224 Gene3D G3DSA:3.40.50.850 21 216 2.4E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS10620 7aeab08fe5c4565b2afc71e797c45ed9 224 SUPERFAMILY SSF52499 13 214 1.44E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS10620 7aeab08fe5c4565b2afc71e797c45ed9 224 Pfam PF00857 Isochorismatase family 27 207 2.3E-39 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 Gene3D G3DSA:2.60.40.420 51 192 5.8E-36 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 ProSitePatterns PS00080 Multicopper oxidases signature 2. 318 329 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 Gene3D G3DSA:2.60.40.420 200 326 6.4E-24 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 Gene3D G3DSA:2.60.40.420 393 413 6.4E-24 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 SUPERFAMILY SSF49503 174 330 1.94E-30 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 Pfam PF07731 Multicopper oxidase 219 333 1.2E-20 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 SUPERFAMILY SSF49503 63 196 6.88E-37 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19660 e3f9a4175fcceacca10686627ce0c925 465 Pfam PF07732 Multicopper oxidase 88 194 2.0E-36 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS15740 24b69c43385c9704fd280fad7f2cbf5e 315 PIRSF PIRSF017082 1 315 5.9E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15740 24b69c43385c9704fd280fad7f2cbf5e 315 SUPERFAMILY SSF53850 110 274 2.25E-7 T 06-07-2017 CAK95_RS15740 24b69c43385c9704fd280fad7f2cbf5e 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 308 1.3E-49 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 3.9E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 656 0.0 T 06-07-2017 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 514 4.5E-137 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 SUPERFAMILY SSF81442 53 570 1.1E-177 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09325 4534e8c185f60f6c7b5f43f2944bd2f1 667 Gene3D G3DSA:1.20.210.10 51 581 1.3E-186 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 359 368 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00385 P450 superfamily signature 290 301 8.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00385 P450 superfamily signature 366 377 8.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00385 P450 superfamily signature 357 366 8.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00385 P450 superfamily signature 255 272 8.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 Gene3D G3DSA:1.10.630.10 12 417 2.8E-109 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 Pfam PF00067 Cytochrome P450 218 387 1.1E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 SUPERFAMILY SSF48264 20 416 2.36E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 366 377 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 307 334 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 357 366 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 101 112 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 290 301 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 335 350 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 208 230 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS09975 9312ee962f10cde117839d8591884b83 418 PRINTS PR00359 B-class P450 signature 147 163 2.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK95_RS01440 e7acfc91fc5159760c984adeb8f3e324 137 SUPERFAMILY SSF140652 5 67 4.71E-5 T 06-07-2017 IPR023089 YozE SAM-like domain CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 Gene3D G3DSA:3.40.50.300 347 576 1.0E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 Pfam PF00005 ABC transporter 364 513 4.2E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 Pfam PF00664 ABC transporter transmembrane region 33 296 4.9E-34 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 SUPERFAMILY SSF52540 340 584 1.93E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 SUPERFAMILY SSF90123 22 335 2.49E-62 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 Gene3D G3DSA:1.20.1560.10 23 332 1.9E-61 T 06-07-2017 CAK95_RS17540 8d9e4e5dc4c4216ba8bf81fa70ea71fa 597 SMART SM00382 373 559 4.5E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07360 d00aed64cef085f0c2113b9c126db8f0 264 Gene3D G3DSA:1.10.3680.10 95 253 1.9E-21 T 06-07-2017 IPR029024 TerB-like CAK95_RS07360 d00aed64cef085f0c2113b9c126db8f0 264 Pfam PF04391 Protein of unknown function (DUF533) 60 250 9.1E-65 T 06-07-2017 IPR007486 Inner membrane protein YebE CAK95_RS07360 d00aed64cef085f0c2113b9c126db8f0 264 SUPERFAMILY SSF158682 96 252 4.97E-22 T 06-07-2017 IPR029024 TerB-like CAK95_RS09770 4ba35bf9e8e84b0cc383abc5cd1d63a3 124 Pfam PF07100 Anabaena sensory rhodopsin transducer 5 121 8.7E-51 T 06-07-2017 IPR009794 Protein of unknown function DUF1362 CAK95_RS09770 4ba35bf9e8e84b0cc383abc5cd1d63a3 124 PIRSF PIRSF008711 1 124 6.6E-56 T 06-07-2017 IPR009794 Protein of unknown function DUF1362 CAK95_RS09770 4ba35bf9e8e84b0cc383abc5cd1d63a3 124 SUPERFAMILY SSF89232 4 123 3.01E-47 T 06-07-2017 IPR009794 Protein of unknown function DUF1362 CAK95_RS09770 4ba35bf9e8e84b0cc383abc5cd1d63a3 124 Gene3D G3DSA:2.60.290.11 2 123 5.8E-50 T 06-07-2017 IPR009794 Protein of unknown function DUF1362 CAK95_RS08610 2960376071aa69fd3dff4e244601cda6 218 Gene3D G3DSA:3.40.50.150 13 190 3.4E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08610 2960376071aa69fd3dff4e244601cda6 218 SUPERFAMILY SSF53335 10 190 5.17E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08610 2960376071aa69fd3dff4e244601cda6 218 Pfam PF13649 Methyltransferase domain 48 148 8.6E-17 T 06-07-2017 CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 Pfam PF01614 Bacterial transcriptional regulator 125 230 2.4E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 Pfam PF09339 IclR helix-turn-helix domain 4 51 2.4E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 SUPERFAMILY SSF55781 58 246 3.2E-23 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 Gene3D G3DSA:1.10.10.10 3 61 3.0E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 SMART SM00346 1 90 2.5E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 Gene3D G3DSA:3.30.450.40 71 237 3.2E-27 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11365 bf8818fc71e487a7f1980309fc587857 260 SUPERFAMILY SSF46785 4 70 2.73E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 Gene3D G3DSA:3.40.140.10 136 276 5.4E-51 T 06-07-2017 CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 Gene3D G3DSA:3.10.20.10 41 122 5.8E-15 T 06-07-2017 CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 PIRSF PIRSF015626 5 275 2.1E-83 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 18 271 26.391 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 Pfam PF02634 FdhD/NarQ family 40 270 1.0E-69 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK95_RS06585 77c8031e670d8b29eb5946f82d608687 295 SUPERFAMILY SSF53927 21 271 2.23E-72 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 SUPERFAMILY SSF51395 20 294 4.21E-80 T 06-07-2017 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 Gene3D G3DSA:3.20.20.70 17 252 2.6E-76 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 PIRSF PIRSF006621 9 340 1.3E-90 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 Pfam PF01207 Dihydrouridine synthase (Dus) 22 303 9.5E-94 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK95_RS23245 c644d85bcc12f567b6c931d55c6e8635 351 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 13 332 4.3E-94 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CAK95_RS17270 2cc7a863bfcd943b40fc3d537e16e53e 230 Gene3D G3DSA:3.50.30.40 25 182 5.1E-52 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS17270 2cc7a863bfcd943b40fc3d537e16e53e 230 Pfam PF03737 Demethylmenaquinone methyltransferase 31 173 2.7E-41 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS17270 2cc7a863bfcd943b40fc3d537e16e53e 230 SUPERFAMILY SSF89562 23 184 2.49E-51 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS17270 2cc7a863bfcd943b40fc3d537e16e53e 230 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 4 224 6.2E-112 T 06-07-2017 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 CAK95_RS17725 25f0565c798335d41dceb94fe8cb95f7 298 SUPERFAMILY SSF52540 3 45 1.55E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17725 25f0565c798335d41dceb94fe8cb95f7 298 SUPERFAMILY SSF52540 85 211 1.55E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17725 25f0565c798335d41dceb94fe8cb95f7 298 Gene3D G3DSA:3.40.50.300 6 283 4.6E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24450 e826751f93bbfe0204445c2c9aefc72f 205 TIGRFAM TIGR02215 phage_chp_gp8: phage conserved hypothetical protein, phiE125 gp8 family 10 205 1.4E-26 T 06-07-2017 IPR011738 Phage conserved hypothetical protein CAK95_RS24450 e826751f93bbfe0204445c2c9aefc72f 205 Pfam PF05135 Phage gp6-like head-tail connector protein 20 56 5.6E-6 T 06-07-2017 IPR021146 Phage gp6-like head-tail connector protein CAK95_RS06950 5a5f70d4b4b9eeb34fa9bed54c1531d1 306 SUPERFAMILY SSF55166 48 303 5.1E-100 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS06950 5a5f70d4b4b9eeb34fa9bed54c1531d1 306 Pfam PF03411 Penicillin-insensitive murein endopeptidase 63 303 6.4E-106 T 06-07-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 CAK95_RS06950 5a5f70d4b4b9eeb34fa9bed54c1531d1 306 Gene3D G3DSA:3.30.1380.10 48 305 4.0E-105 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS06950 5a5f70d4b4b9eeb34fa9bed54c1531d1 306 PIRSF PIRSF018455 7 306 1.2E-120 T 06-07-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 SUPERFAMILY SSF49503 305 327 1.53E-32 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 SUPERFAMILY SSF49503 365 478 1.53E-32 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 ProSitePatterns PS00079 Multicopper oxidases signature 1. 456 476 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Gene3D G3DSA:2.60.40.420 358 478 1.2E-38 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Pfam PF07732 Multicopper oxidase 59 162 4.2E-38 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 ProSitePatterns PS00080 Multicopper oxidases signature 2. 461 472 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Gene3D G3DSA:2.60.40.420 163 287 1.2E-26 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Pfam PF07731 Multicopper oxidase 382 478 1.5E-27 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Pfam PF00394 Multicopper oxidase 170 291 3.4E-10 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 SUPERFAMILY SSF49503 164 322 1.14E-20 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 SUPERFAMILY SSF49503 35 187 1.09E-37 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS04165 30b37ab1385fd60fa2490e88db3109bc 479 Gene3D G3DSA:2.60.40.420 34 162 1.1E-34 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS12650 45bf2ca39613f071ddc4a360848d5cd8 248 Pfam PF06707 Protein of unknown function (DUF1194) 26 234 4.6E-68 T 06-07-2017 IPR010607 Protein of unknown function DUF1194 CAK95_RS12650 45bf2ca39613f071ddc4a360848d5cd8 248 SUPERFAMILY SSF53300 30 225 2.19E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS22470 e5402a1c7c47d1c42df66fc3dec92a57 406 Gene3D G3DSA:1.20.1250.20 220 397 1.7E-15 T 06-07-2017 CAK95_RS22470 e5402a1c7c47d1c42df66fc3dec92a57 406 Gene3D G3DSA:1.20.1250.20 30 203 6.2E-9 T 06-07-2017 CAK95_RS22470 e5402a1c7c47d1c42df66fc3dec92a57 406 Pfam PF07690 Major Facilitator Superfamily 229 398 2.8E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS22470 e5402a1c7c47d1c42df66fc3dec92a57 406 Pfam PF00083 Sugar (and other) transporter 18 193 1.2E-7 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK95_RS22470 e5402a1c7c47d1c42df66fc3dec92a57 406 SUPERFAMILY SSF103473 16 397 3.01E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS20135 9678fb7a1bbb8d72f17806300e529f39 113 SMART SM00450 14 109 5.5E-16 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS20135 9678fb7a1bbb8d72f17806300e529f39 113 Pfam PF00581 Rhodanese-like domain 16 106 1.0E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS20135 9678fb7a1bbb8d72f17806300e529f39 113 Gene3D G3DSA:3.40.250.10 3 113 1.0E-24 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS20135 9678fb7a1bbb8d72f17806300e529f39 113 SUPERFAMILY SSF52821 10 112 5.89E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS08585 755a3198ada19cc71e522266d205e552 140 Gene3D G3DSA:1.10.10.10 6 49 4.6E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08585 755a3198ada19cc71e522266d205e552 140 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 50 1.1E-14 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK95_RS08585 755a3198ada19cc71e522266d205e552 140 Pfam PF12728 Helix-turn-helix domain 5 50 1.0E-12 T 06-07-2017 CAK95_RS08585 755a3198ada19cc71e522266d205e552 140 SUPERFAMILY SSF46955 6 51 5.77E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 Pfam PF12840 Helix-turn-helix domain 13 70 3.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 SUPERFAMILY SSF46785 6 104 8.47E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 Gene3D G3DSA:1.10.10.10 7 109 2.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.8E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.8E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.8E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS12050 2e185b46306defcbeda1b8df2d81f031 146 SMART SM00418 11 90 2.0E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS16320 18c7797480e90b12e91db0c14cd8ac99 334 Gene3D G3DSA:1.20.58.340 262 332 8.4E-16 T 06-07-2017 CAK95_RS16320 18c7797480e90b12e91db0c14cd8ac99 334 SUPERFAMILY SSF144083 270 330 1.57E-14 T 06-07-2017 CAK95_RS16320 18c7797480e90b12e91db0c14cd8ac99 334 Pfam PF01544 CorA-like Mg2+ transporter protein 46 329 1.4E-50 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAK95_RS16320 18c7797480e90b12e91db0c14cd8ac99 334 Gene3D G3DSA:1.20.58.340 152 239 1.7E-8 T 06-07-2017 CAK95_RS16320 18c7797480e90b12e91db0c14cd8ac99 334 SUPERFAMILY SSF143865 9 244 1.44E-33 T 06-07-2017 CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 SUPERFAMILY SSF53850 34 265 3.07E-50 T 06-07-2017 CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 Gene3D G3DSA:3.40.190.10 229 274 9.7E-4 T 06-07-2017 CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 37 320 1.7E-74 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 SMART SM00062 36 251 0.0027 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 Pfam PF09084 NMT1/THI5 like 61 254 7.5E-25 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS06280 f413abdcc6ccb326254e01cdf3c48f62 328 Gene3D G3DSA:3.40.190.10 117 228 1.8E-26 T 06-07-2017 CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 SUPERFAMILY SSF52833 3 84 5.97E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 5 84 6.0E-28 T 06-07-2017 IPR011900 Glutaredoxin, GrxC GO:0045454 CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 Gene3D G3DSA:3.40.30.10 2 81 3.0E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 PRINTS PR00160 Glutaredoxin signature 5 23 2.7E-6 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 PRINTS PR00160 Glutaredoxin signature 48 61 2.7E-6 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 06-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CAK95_RS12540 e4bef3713ad1af755cd1494d7eeaa7fd 90 Pfam PF00462 Glutaredoxin 5 65 9.2E-18 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK95_RS06185 fef92ec9f2dad780c00664e488621ccf 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 262 4.1E-37 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS06185 fef92ec9f2dad780c00664e488621ccf 268 Gene3D G3DSA:3.90.226.10 14 260 1.7E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06185 fef92ec9f2dad780c00664e488621ccf 268 SUPERFAMILY SSF52096 14 266 2.44E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS15500 72c7634da8dd63eb0a0b3b45e691386e 265 Gene3D G3DSA:3.40.50.1820 29 253 6.7E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15500 72c7634da8dd63eb0a0b3b45e691386e 265 Pfam PF12697 Alpha/beta hydrolase family 31 246 1.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS15500 72c7634da8dd63eb0a0b3b45e691386e 265 SUPERFAMILY SSF53474 187 250 5.74E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15500 72c7634da8dd63eb0a0b3b45e691386e 265 SUPERFAMILY SSF53474 22 160 5.74E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 SUPERFAMILY SSF51735 6 262 9.61E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 Gene3D G3DSA:3.40.50.720 1 262 2.5E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 260 4.1E-55 T 06-07-2017 CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07910 11bdef2fda71bdbf596b9b951aa7e1e5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS23480 5d4fc9c7dc6a1637732a0f0ea04a5220 121 SUPERFAMILY SSF46626 22 108 2.4E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23480 5d4fc9c7dc6a1637732a0f0ea04a5220 121 Gene3D G3DSA:1.10.760.10 41 109 3.3E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS12015 fe159cb3b677721c4156a8da02845e40 120 Gene3D G3DSA:3.30.70.900 1 119 1.4E-47 T 06-07-2017 CAK95_RS12015 fe159cb3b677721c4156a8da02845e40 120 SUPERFAMILY SSF54909 1 119 2.25E-45 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS12015 fe159cb3b677721c4156a8da02845e40 120 PIRSF PIRSF007028 1 120 1.5E-49 T 06-07-2017 IPR009874 Protein of unknown function DUF1428 CAK95_RS12015 fe159cb3b677721c4156a8da02845e40 120 Pfam PF07237 Protein of unknown function (DUF1428) 3 105 8.4E-42 T 06-07-2017 IPR009874 Protein of unknown function DUF1428 CAK95_RS06215 500335252e7fdde9df46d0e6deb5dd54 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 313 2.8E-40 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 SUPERFAMILY SSF51905 9 175 2.23E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 SUPERFAMILY SSF51905 265 380 2.23E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 9 382 7.3E-97 T 06-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 Pfam PF01494 FAD binding domain 8 335 4.3E-30 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 2.0E-23 T 06-07-2017 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 2.0E-23 T 06-07-2017 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 2.0E-23 T 06-07-2017 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 2.0E-23 T 06-07-2017 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 Gene3D G3DSA:3.50.50.60 266 348 3.8E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS23560 3d903b56e2b93d185cd9a9f727593657 400 Gene3D G3DSA:3.50.50.60 9 180 3.8E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20130 27a64793f6e1dc2ff1c3b4e02b8f1e97 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 90 199 9.1E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS20130 27a64793f6e1dc2ff1c3b4e02b8f1e97 727 Pfam PF00593 TonB dependent receptor 475 692 2.7E-12 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS20130 27a64793f6e1dc2ff1c3b4e02b8f1e97 727 Gene3D G3DSA:2.40.170.20 213 727 2.6E-32 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS20130 27a64793f6e1dc2ff1c3b4e02b8f1e97 727 Gene3D G3DSA:2.170.130.10 88 202 3.7E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS20130 27a64793f6e1dc2ff1c3b4e02b8f1e97 727 SUPERFAMILY SSF56935 51 724 3.63E-72 T 06-07-2017 CAK95_RS15830 f2b72f0938c81decd48414187d093b1d 227 SUPERFAMILY SSF141523 64 203 4.05E-29 T 06-07-2017 CAK95_RS15830 f2b72f0938c81decd48414187d093b1d 227 Pfam PF03734 L,D-transpeptidase catalytic domain 70 202 2.0E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS15830 f2b72f0938c81decd48414187d093b1d 227 Gene3D G3DSA:2.40.440.10 64 203 8.7E-31 T 06-07-2017 CAK95_RS17680 8ee6199f1f562ca84dc0516bbf8ec32a 336 Gene3D G3DSA:3.30.360.10 141 331 3.1E-31 T 06-07-2017 CAK95_RS17680 8ee6199f1f562ca84dc0516bbf8ec32a 336 Gene3D G3DSA:3.40.50.720 6 140 1.3E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17680 8ee6199f1f562ca84dc0516bbf8ec32a 336 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.6E-16 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS17680 8ee6199f1f562ca84dc0516bbf8ec32a 336 SUPERFAMILY SSF51735 7 152 5.38E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17680 8ee6199f1f562ca84dc0516bbf8ec32a 336 SUPERFAMILY SSF55347 127 279 1.8E-28 T 06-07-2017 CAK95_RS15730 cbea132af25663172d48296a3ad0a8fc 325 SUPERFAMILY SSF54593 35 303 4.72E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS15730 cbea132af25663172d48296a3ad0a8fc 325 Pfam PF13468 Glyoxalase-like domain 46 231 1.7E-29 T 06-07-2017 IPR025870 Glyoxalase-like domain CAK95_RS15730 cbea132af25663172d48296a3ad0a8fc 325 Gene3D G3DSA:3.10.180.10 41 151 2.8E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS25080 0dfbfb2569e5a2723a1bd51e47f3d398 254 Gene3D G3DSA:3.40.50.1820 12 249 2.0E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25080 0dfbfb2569e5a2723a1bd51e47f3d398 254 SUPERFAMILY SSF53474 13 247 7.08E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25080 0dfbfb2569e5a2723a1bd51e47f3d398 254 Pfam PF12697 Alpha/beta hydrolase family 26 233 1.3E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS25080 0dfbfb2569e5a2723a1bd51e47f3d398 254 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 88 102 2.4E-5 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAK95_RS25080 0dfbfb2569e5a2723a1bd51e47f3d398 254 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 25 33 2.4E-5 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 Pfam PF01979 Amidohydrolase family 72 433 1.5E-53 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 SUPERFAMILY SSF51556 74 378 6.38E-94 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 SUPERFAMILY SSF51338 32 91 6.48E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 SUPERFAMILY SSF51338 374 433 6.26E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 Gene3D G3DSA:3.20.20.140 83 366 2.7E-103 T 06-07-2017 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 Gene3D G3DSA:2.30.40.10 367 433 1.6E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 Gene3D G3DSA:2.30.40.10 29 82 6.7E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS23135 89d60524e64ed018689099024f2b96d5 443 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 32 432 2.2E-168 T 06-07-2017 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 CAK95_RS05740 6f73f88065615702e95748994a9f7630 169 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 8.5E-61 T 06-07-2017 IPR018531 Domain of unknown function DUF1993 CAK95_RS05740 6f73f88065615702e95748994a9f7630 169 Gene3D G3DSA:1.20.120.450 1 165 6.5E-66 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK95_RS05740 6f73f88065615702e95748994a9f7630 169 SUPERFAMILY SSF109854 4 166 6.68E-57 T 06-07-2017 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 312 528 3.7E-24 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 SUPERFAMILY SSF53474 5 307 5.93E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 6 533 5.0E-102 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Gene3D G3DSA:3.40.50.1820 217 323 6.4E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Gene3D G3DSA:3.40.50.1820 3 139 6.4E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Gene3D G3DSA:2.60.120.260 324 532 1.4E-47 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 SMART SM00939 296 529 3.6E-45 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Gene3D G3DSA:1.10.3020.10 140 216 5.6E-6 T 06-07-2017 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 6 272 5.3E-53 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK95_RS28680 7452be7005d1a06b7268f29b630d4b60 535 SUPERFAMILY SSF49785 329 532 9.57E-44 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS06630 86a908e3daf5310fd0b2f09b1eb7c941 164 Pfam PF13629 Pilus formation protein N terminal region 37 106 6.4E-19 T 06-07-2017 IPR032789 Pilus formation protein, N-terminal CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 32 555 7.5E-215 T 06-07-2017 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 47 1.1E-7 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 224 1.1E-7 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 64 77 1.1E-7 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 32 337 8.8E-103 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 SUPERFAMILY SSF52374 16 341 2.28E-96 T 06-07-2017 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 344 533 1.7E-57 T 06-07-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:1.10.1160.10 267 343 1.2E-33 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:2.40.240.10 352 466 1.6E-51 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:2.40.240.10 467 551 3.7E-26 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 5 553 52.013 T 06-07-2017 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 38 49 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:3.90.800.10 105 213 1.1E-44 T 06-07-2017 CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:3.40.50.620 32 100 1.9E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 Gene3D G3DSA:3.40.50.620 216 266 1.9E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23055 6d61d1a347ce10eb12033dd4b399fa08 560 SUPERFAMILY SSF50715 344 551 1.26E-68 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS27170 80bdbbb2bca076a5aa78a8632003f832 384 SUPERFAMILY SSF89796 3 371 1.96E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS27170 80bdbbb2bca076a5aa78a8632003f832 384 Gene3D G3DSA:3.30.1540.10 223 305 4.8E-33 T 06-07-2017 CAK95_RS27170 80bdbbb2bca076a5aa78a8632003f832 384 Gene3D G3DSA:3.40.50.10540 2 217 1.4E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS27170 80bdbbb2bca076a5aa78a8632003f832 384 Gene3D G3DSA:3.40.50.10540 306 371 1.4E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS27170 80bdbbb2bca076a5aa78a8632003f832 384 Pfam PF02515 CoA-transferase family III 5 370 3.7E-120 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 Pfam PF00593 TonB dependent receptor 496 730 7.4E-19 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 Gene3D G3DSA:2.40.170.20 208 731 1.3E-128 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 Gene3D G3DSA:2.170.130.10 75 200 8.2E-38 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 95 731 1.2E-85 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 94 193 3.2E-20 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAK95_RS18240 fbbc18d6ae46b4afaff75fdc4914bf73 731 SUPERFAMILY SSF56935 85 731 1.68E-118 T 06-07-2017 CAK95_RS16575 2c0c15ba4839f73abc3f860e3d71bded 91 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 17 88 1.3E-34 T 06-07-2017 IPR018753 Azospirillum phage Cd, Gp10 CAK95_RS16575 2c0c15ba4839f73abc3f860e3d71bded 91 Hamap MF_00797 UPF0335 protein . 12 89 22.469 T 06-07-2017 IPR018753 Azospirillum phage Cd, Gp10 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 51 247 4.5E-90 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 Pfam PF00813 FliP family 51 243 4.5E-81 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 47 56 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 147 159 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 169 181 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 107 119 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 119 133 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 237 247 8.2E-26 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 49 68 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 221 246 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 88 107 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 197 218 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 68 88 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 176 196 1.1E-65 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 224 236 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS18265 6bc734aeeba6fe2e162b7cc63d5eaf22 249 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 176 191 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAK95_RS19670 2eba13005293971168f4a5798287cd51 105 Pfam PF11604 Copper binding periplasmic protein CusF 36 103 1.1E-26 T 06-07-2017 IPR021647 Copper binding periplasmic protein CusF CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 PIRSF PIRSF000429 3 397 1.9E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Gene3D G3DSA:3.40.47.10 199 279 5.4E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Gene3D G3DSA:3.40.47.10 8 127 5.4E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 SUPERFAMILY SSF53901 8 273 6.01E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 SUPERFAMILY SSF53901 275 395 3.74E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Gene3D G3DSA:3.40.47.10 280 395 4.7E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Gene3D G3DSA:3.40.47.10 146 198 4.7E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 394 1.2E-124 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Pfam PF02803 Thiolase, C-terminal domain 274 395 1.1E-45 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 Pfam PF00108 Thiolase, N-terminal domain 8 265 5.0E-79 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS26200 27966e1e0c9409990b55e59f99c26a14 397 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 SMART SM00347 29 133 3.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 Gene3D G3DSA:1.10.10.10 6 145 6.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 Pfam PF12802 MarR family 39 96 6.8E-14 T 06-07-2017 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 SUPERFAMILY SSF46785 9 145 1.52E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 9.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 9.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 9.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS26395 5aa7ab17fa4be5b652aa651c6d5b30ec 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 9.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Gene3D G3DSA:2.170.220.10 118 230 2.5E-45 T 06-07-2017 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 SUPERFAMILY SSF47323 354 510 1.2E-38 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Pfam PF09334 tRNA synthetases class I (M) 7 365 3.6E-112 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 25 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Gene3D G3DSA:3.40.50.620 231 340 1.3E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Gene3D G3DSA:3.40.50.620 4 115 1.3E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Pfam PF08264 Anticodon-binding domain of tRNA 387 468 3.9E-6 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 SUPERFAMILY SSF52374 4 352 6.7E-110 T 06-07-2017 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Gene3D G3DSA:1.10.730.10 342 510 3.9E-53 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 488 2.9E-155 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 Hamap MF_01228 Methionine--tRNA ligase [metG]. 3 510 47.099 T 06-07-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 353 364 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 261 276 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 229 240 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS23315 a7cca327604c5a4a083000459d5c5bf4 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 2.6E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 8 332 6.9E-146 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 Pfam PF00107 Zinc-binding dehydrogenase 158 277 2.1E-30 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 SMART SM00829 17 330 8.0E-48 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 SUPERFAMILY SSF51735 119 294 2.29E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 Gene3D G3DSA:3.90.180.10 7 151 2.6E-50 T 06-07-2017 IPR011032 GroES-like CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 Gene3D G3DSA:3.40.50.720 152 269 1.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 107 3.5E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS04230 98ca6a45b1f4484066c10af4fb33376a 332 SUPERFAMILY SSF50129 8 156 6.54E-39 T 06-07-2017 IPR011032 GroES-like CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 Pfam PF00106 short chain dehydrogenase 13 208 1.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 Gene3D G3DSA:3.40.50.720 13 257 2.3E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 SUPERFAMILY SSF51735 13 258 1.48E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS00100 c90e257a099c458197f8c8b20781182e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13255 18651355247195cc68928aa82cd78a28 171 Pfam PF12680 SnoaL-like domain 23 132 2.8E-12 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS13255 18651355247195cc68928aa82cd78a28 171 SUPERFAMILY SSF54427 19 145 1.31E-27 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS13255 18651355247195cc68928aa82cd78a28 171 Gene3D G3DSA:3.10.450.50 21 155 4.2E-32 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS19665 c78dec64a5711574dbb9dac21455927c 163 SUPERFAMILY SSF49503 56 162 3.88E-30 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS19665 c78dec64a5711574dbb9dac21455927c 163 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 58 163 2.0E-10 T 06-07-2017 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CAK95_RS19665 c78dec64a5711574dbb9dac21455927c 163 Gene3D G3DSA:2.60.40.420 39 162 2.0E-32 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS09670 ba92f8fb4a465bbbc7dbfecd35de5a71 237 Gene3D G3DSA:3.40.50.300 3 233 2.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09670 ba92f8fb4a465bbbc7dbfecd35de5a71 237 SUPERFAMILY SSF52540 4 234 1.02E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09670 ba92f8fb4a465bbbc7dbfecd35de5a71 237 SMART SM00382 30 214 3.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS09670 ba92f8fb4a465bbbc7dbfecd35de5a71 237 Pfam PF00005 ABC transporter 23 165 1.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09670 ba92f8fb4a465bbbc7dbfecd35de5a71 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS18820 db65a44e74bcbadf596e6e77df1abbc2 117 SUPERFAMILY SSF46785 19 111 2.28E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18820 db65a44e74bcbadf596e6e77df1abbc2 117 Gene3D G3DSA:1.10.10.10 18 111 6.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18820 db65a44e74bcbadf596e6e77df1abbc2 117 Pfam PF01638 HxlR-like helix-turn-helix 30 112 5.4E-23 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS20245 4191bcce4705b40ed45d477833e73498 334 Pfam PF03576 Peptidase family S58 3 317 9.5E-64 T 06-07-2017 IPR005321 Peptidase S58, DmpA CAK95_RS20245 4191bcce4705b40ed45d477833e73498 334 SUPERFAMILY SSF56266 2 315 9.94E-68 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS20245 4191bcce4705b40ed45d477833e73498 334 Gene3D G3DSA:3.60.70.12 2 316 3.2E-81 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 9 241 6.9E-106 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 SUPERFAMILY SSF49503 124 282 3.73E-50 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 Gene3D G3DSA:2.60.40.420 125 281 1.4E-39 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 152 222 6.2E-8 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 Pfam PF06481 COX Aromatic Rich Motif 241 286 1.9E-18 T 06-07-2017 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 Gene3D G3DSA:1.10.287.90 22 106 2.2E-33 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09320 00b9e563e00e3869ab098dcceabb128e 385 SUPERFAMILY SSF81464 12 111 5.23E-23 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS22640 223f4f48b23d343e43714f39f1c08c27 192 SUPERFAMILY SSF51735 7 140 1.24E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22640 223f4f48b23d343e43714f39f1c08c27 192 Pfam PF13380 CoA binding domain 19 137 7.6E-38 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS22640 223f4f48b23d343e43714f39f1c08c27 192 Gene3D G3DSA:3.40.50.720 8 146 1.8E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22640 223f4f48b23d343e43714f39f1c08c27 192 SMART SM00881 14 111 1.5E-22 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS03985 c43c71838361271cd3d30dc8eeda28ce 381 Gene3D G3DSA:2.40.50.100 60 93 1.2E-15 T 06-07-2017 CAK95_RS03985 c43c71838361271cd3d30dc8eeda28ce 381 Gene3D G3DSA:2.40.50.100 168 197 1.2E-15 T 06-07-2017 CAK95_RS03985 c43c71838361271cd3d30dc8eeda28ce 381 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 370 9.7E-83 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS03985 c43c71838361271cd3d30dc8eeda28ce 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 290 1.1E-17 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS03985 c43c71838361271cd3d30dc8eeda28ce 381 SUPERFAMILY SSF111369 49 295 4.32E-62 T 06-07-2017 CAK95_RS03880 c1522e6bf87dcd6e5468fdc70cf80362 274 Pfam PF13847 Methyltransferase domain 68 193 2.4E-10 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS03880 c1522e6bf87dcd6e5468fdc70cf80362 274 Gene3D G3DSA:3.40.50.150 49 175 1.8E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03880 c1522e6bf87dcd6e5468fdc70cf80362 274 SUPERFAMILY SSF53335 45 171 1.3E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 Gene3D G3DSA:3.40.605.10 3 258 1.5E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 SUPERFAMILY SSF53720 3 472 1.28E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 Pfam PF00171 Aldehyde dehydrogenase family 11 468 9.3E-158 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS02210 bc8969d534c8665a04560b8d8accbaaa 488 Gene3D G3DSA:3.40.309.10 259 444 7.4E-61 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 Pfam PF13768 von Willebrand factor type A domain 309 461 9.0E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 TIGRFAM TIGR03788 marine_srt_targ: marine proteobacterial sortase target protein 39 723 1.7E-242 T 06-07-2017 IPR022440 Conserved hypothetical protein CHP03788 CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 SMART SM00609 31 148 2.5E-7 T 06-07-2017 IPR013694 VIT domain CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 Pfam PF08487 Vault protein inter-alpha-trypsin domain 40 146 2.9E-28 T 06-07-2017 IPR013694 VIT domain CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 SMART SM00327 307 482 5.9E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 Gene3D G3DSA:3.40.50.410 306 477 1.2E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS07800 43681271b9e656d97d56ea50092b5ab6 731 SUPERFAMILY SSF53300 310 481 5.01E-27 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS12495 cb86d1b25eaaa3e7194ae13cd56f751f 282 Gene3D G3DSA:1.10.3720.10 77 269 8.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12495 cb86d1b25eaaa3e7194ae13cd56f751f 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 274 2.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS12495 cb86d1b25eaaa3e7194ae13cd56f751f 282 SUPERFAMILY SSF161098 79 259 4.58E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06320 537d891b35e95fe16f59e2cd0070c636 444 Pfam PF06850 PHB de-polymerase C-terminus 229 427 1.2E-101 T 06-07-2017 IPR009656 PHB de-polymerase, C-terminal CAK95_RS06320 537d891b35e95fe16f59e2cd0070c636 444 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 25 427 1.0E-190 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAK95_RS06320 537d891b35e95fe16f59e2cd0070c636 444 PIRSF PIRSF020818 19 439 7.5E-203 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAK95_RS06320 537d891b35e95fe16f59e2cd0070c636 444 Gene3D G3DSA:3.40.50.1820 121 426 2.0E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06320 537d891b35e95fe16f59e2cd0070c636 444 SUPERFAMILY SSF53474 119 426 8.89E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22020 68e7d75b8a7ddf5ef540785d95bedc05 99 Pfam PF12096 Protein of unknown function (DUF3572) 10 91 1.9E-29 T 06-07-2017 IPR021955 Protein of unknown function DUF3572 CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 SUPERFAMILY SSF52540 272 502 2.66E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 SMART SM00382 306 497 7.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 SMART SM00382 41 271 4.2E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 SUPERFAMILY SSF52540 15 243 1.54E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 Pfam PF12698 ABC-2 family transporter protein 583 922 6.1E-36 T 06-07-2017 CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 Gene3D G3DSA:3.40.50.300 10 245 4.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 Gene3D G3DSA:3.40.50.300 272 503 3.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 Pfam PF00005 ABC transporter 297 441 1.8E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16795 c62cff689de0380fee6a65fbd67d1c4b 930 Pfam PF00005 ABC transporter 33 179 4.5E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09405 a9150560c448dcd99d45ba0ab3a17f73 474 Gene3D G3DSA:3.40.605.10 14 241 1.0E-31 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS09405 a9150560c448dcd99d45ba0ab3a17f73 474 SUPERFAMILY SSF53720 14 450 1.24E-71 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS09405 a9150560c448dcd99d45ba0ab3a17f73 474 Pfam PF00171 Aldehyde dehydrogenase family 14 278 2.2E-24 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS09405 a9150560c448dcd99d45ba0ab3a17f73 474 Gene3D G3DSA:3.40.309.10 242 408 4.8E-14 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS26920 45ff296c784da6bfb35399f849365877 301 SUPERFAMILY SSF53335 6 196 1.41E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26920 45ff296c784da6bfb35399f849365877 301 Gene3D G3DSA:3.40.50.150 53 214 1.4E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26920 45ff296c784da6bfb35399f849365877 301 Pfam PF13489 Methyltransferase domain 56 187 1.6E-8 T 06-07-2017 CAK95_RS03425 2d7544caf8457aef32c136c2e8e2f112 81 Gene3D G3DSA:1.10.10.10 13 66 1.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03425 2d7544caf8457aef32c136c2e8e2f112 81 SUPERFAMILY SSF46955 18 71 8.61E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS03425 2d7544caf8457aef32c136c2e8e2f112 81 Pfam PF12728 Helix-turn-helix domain 18 63 6.9E-10 T 06-07-2017 CAK95_RS27280 f9f6df311015b2174d1d657071e31e6e 377 Gene3D G3DSA:3.40.50.2300 8 137 4.7E-40 T 06-07-2017 CAK95_RS27280 f9f6df311015b2174d1d657071e31e6e 377 Gene3D G3DSA:3.40.50.2300 286 340 4.7E-40 T 06-07-2017 CAK95_RS27280 f9f6df311015b2174d1d657071e31e6e 377 SUPERFAMILY SSF53822 13 373 6.18E-83 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS27280 f9f6df311015b2174d1d657071e31e6e 377 Gene3D G3DSA:3.40.50.2300 145 285 6.7E-22 T 06-07-2017 CAK95_RS27280 f9f6df311015b2174d1d657071e31e6e 377 Pfam PF13458 Periplasmic binding protein 13 349 2.5E-70 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS09370 7b65bd8c2470b703628434c3ab4b8b49 369 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 330 4.5E-38 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS09370 7b65bd8c2470b703628434c3ab4b8b49 369 PIRSF PIRSF039026 2 364 1.5E-106 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAK95_RS00110 313cdfa9c42890343d44c53325b5a0b5 152 Gene3D G3DSA:3.10.129.10 14 150 2.0E-28 T 06-07-2017 IPR029069 HotDog domain CAK95_RS00110 313cdfa9c42890343d44c53325b5a0b5 152 Pfam PF01575 MaoC like domain 11 125 6.3E-20 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS00110 313cdfa9c42890343d44c53325b5a0b5 152 SUPERFAMILY SSF54637 5 147 4.48E-29 T 06-07-2017 IPR029069 HotDog domain CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 467 4.9E-54 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 Gene3D G3DSA:3.30.465.10 98 218 1.8E-35 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 Gene3D G3DSA:1.10.45.10 428 467 9.9E-17 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 Gene3D G3DSA:3.30.43.10 4 95 2.3E-26 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 SUPERFAMILY SSF55103 222 468 1.34E-56 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 SUPERFAMILY SSF56176 6 218 1.2E-71 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS15760 5f2853d856ad348de18fdc5b29b0ce51 468 Pfam PF01565 FAD binding domain 43 178 5.0E-34 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS07585 086e7dfa0d789b20a3d5488ad0a5b371 202 ProSitePatterns PS00194 Thioredoxin family active site. 85 103 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS07585 086e7dfa0d789b20a3d5488ad0a5b371 202 Pfam PF08534 Redoxin 75 182 1.1E-14 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK95_RS07585 086e7dfa0d789b20a3d5488ad0a5b371 202 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 19 192 8.3E-52 T 06-07-2017 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 CAK95_RS07585 086e7dfa0d789b20a3d5488ad0a5b371 202 Gene3D G3DSA:3.40.30.10 22 192 2.0E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS07585 086e7dfa0d789b20a3d5488ad0a5b371 202 SUPERFAMILY SSF52833 47 191 1.6E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01545 f634c56cb9a37d04d9f0ed2e0b555d4d 437 Gene3D G3DSA:1.20.1530.10 19 259 1.1E-123 T 06-07-2017 IPR023171 Na/H antiporter domain CAK95_RS01545 f634c56cb9a37d04d9f0ed2e0b555d4d 437 Gene3D G3DSA:1.20.1530.10 300 432 1.1E-123 T 06-07-2017 IPR023171 Na/H antiporter domain CAK95_RS01545 f634c56cb9a37d04d9f0ed2e0b555d4d 437 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 20 436 20.896 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS01545 f634c56cb9a37d04d9f0ed2e0b555d4d 437 Pfam PF06965 Na+/H+ antiporter 1 22 428 2.2E-125 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS01545 f634c56cb9a37d04d9f0ed2e0b555d4d 437 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 23 426 5.9E-98 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS13500 907b2573278d452fbd6cec108d1d2125 102 Pfam PF04380 Membrane fusogenic activity 5 79 2.7E-25 T 06-07-2017 IPR007475 Membrane fusogenic activity CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 Gene3D G3DSA:1.10.1670.10 135 226 1.1E-22 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 Gene3D G3DSA:1.10.340.30 34 134 4.4E-12 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 SMART SM00525 206 226 2.5E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 207 223 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 169 4.0E-6 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 PIRSF PIRSF001435 6 230 3.2E-35 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 SUPERFAMILY SSF48150 15 225 2.36E-38 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK95_RS19235 b07c06bbd79c80524a4c5ca6846cc3ad 231 SMART SM00478 44 205 1.2E-5 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK95_RS18840 4afb42eb4f04520db8c639798743d7f7 141 Pfam PF02657 Fe-S metabolism associated domain 8 132 3.3E-48 T 06-07-2017 IPR003808 Fe-S metabolism associated domain, SufE-like CAK95_RS18840 4afb42eb4f04520db8c639798743d7f7 141 Gene3D G3DSA:3.90.1010.10 2 138 2.9E-55 T 06-07-2017 CAK95_RS18840 4afb42eb4f04520db8c639798743d7f7 141 SUPERFAMILY SSF82649 2 136 3.61E-47 T 06-07-2017 CAK95_RS10980 94a3ec842cdf19f9a1d732113cbb9882 419 SUPERFAMILY SSF103473 23 417 7.98E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS10980 94a3ec842cdf19f9a1d732113cbb9882 419 Gene3D G3DSA:1.20.1250.20 231 418 1.8E-21 T 06-07-2017 CAK95_RS10980 94a3ec842cdf19f9a1d732113cbb9882 419 Pfam PF07690 Major Facilitator Superfamily 35 316 3.9E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS10980 94a3ec842cdf19f9a1d732113cbb9882 419 Gene3D G3DSA:1.20.1250.20 33 198 4.3E-13 T 06-07-2017 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 Gene3D G3DSA:1.10.150.240 20 86 1.5E-13 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 Gene3D G3DSA:3.40.50.1000 1 19 1.6E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 Gene3D G3DSA:3.40.50.1000 87 217 1.6E-38 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 189 1.4E-36 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 59 189 7.4E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 6 216 2.7E-55 T 06-07-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 SUPERFAMILY SSF56784 5 219 3.53E-54 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS19925 293d0a77fc094e4efeba71cc4db29693 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 183 9.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS05390 3b1bf4b33b07c9616154ba7b2c156307 156 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 5 155 7.3E-51 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAK95_RS05390 3b1bf4b33b07c9616154ba7b2c156307 156 SUPERFAMILY SSF55826 5 155 5.1E-42 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS05390 3b1bf4b33b07c9616154ba7b2c156307 156 Pfam PF04073 Aminoacyl-tRNA editing domain 29 146 2.3E-24 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS05390 3b1bf4b33b07c9616154ba7b2c156307 156 Gene3D G3DSA:3.90.960.10 3 156 5.4E-54 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK95_RS05390 3b1bf4b33b07c9616154ba7b2c156307 156 PIRSF PIRSF006181 1 156 5.8E-50 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 255 272 6.0E-5 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 183 205 6.0E-5 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 39 56 6.0E-5 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 Gene3D G3DSA:2.120.10.30 38 325 1.9E-55 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 40 309 2.2E-39 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAK95_RS00840 607da03c7c904f956813497c39b10b35 327 SUPERFAMILY SSF63829 34 325 5.45E-50 T 06-07-2017 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 SUPERFAMILY SSF53474 2 272 2.82E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28100 978f35659b650c570654e3f690a435da 280 Pfam PF00561 alpha/beta hydrolase fold 22 253 9.4E-26 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 5.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 Gene3D G3DSA:3.40.50.1820 3 272 2.8E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00412 Epoxide hydrolase signature 248 270 6.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00412 Epoxide hydrolase signature 214 230 6.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS28100 978f35659b650c570654e3f690a435da 280 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 Gene3D G3DSA:3.40.50.970 2 357 2.2E-90 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 Gene3D G3DSA:3.40.50.920 636 783 2.2E-26 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 SUPERFAMILY SSF52922 630 786 2.67E-27 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 SUPERFAMILY SSF52518 3 363 1.18E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 PIRSF PIRSF000156 2 789 3.6E-55 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 SUPERFAMILY SSF52518 388 626 1.18E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 Gene3D G3DSA:3.40.50.970 388 632 7.2E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 48 221 2.9E-8 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK95_RS06960 5453d04c10d2380e6d55ef8d2d7f6871 796 SMART SM00861 406 625 2.9E-4 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK95_RS04025 0d833bca239e7015827813ffcba92d61 190 SUPERFAMILY SSF46689 13 80 2.26E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS04025 0d833bca239e7015827813ffcba92d61 190 SUPERFAMILY SSF48498 88 189 9.89E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS04025 0d833bca239e7015827813ffcba92d61 190 Gene3D G3DSA:1.10.357.10 10 186 5.8E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS04025 0d833bca239e7015827813ffcba92d61 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 Gene3D G3DSA:3.40.640.10 48 295 1.2E-107 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 18 433 53.078 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 PIRSF PIRSF000412 3 433 1.9E-166 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 Pfam PF00464 Serine hydroxymethyltransferase 19 396 1.0E-177 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 SUPERFAMILY SSF53383 14 432 6.25E-178 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 Gene3D G3DSA:3.90.1150.10 296 433 2.9E-51 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS22430 8f9615eb4ed19d89d95343086d02b504 433 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 233 249 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK95_RS26520 c6b3938d1dee11ace89ad72f334d9278 246 SUPERFAMILY SSF56281 14 245 1.9E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS26520 c6b3938d1dee11ace89ad72f334d9278 246 Pfam PF14234 Domain of unknown function (DUF4336) 37 164 8.9E-12 T 06-07-2017 IPR025638 Protein of unknown function DUF4336 CAK95_RS10290 7b8b125f9f045ac470ab1d72b52e3622 410 Pfam PF12704 MacB-like periplasmic core domain 21 249 2.6E-39 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAK95_RS10290 7b8b125f9f045ac470ab1d72b52e3622 410 Pfam PF02687 FtsX-like permease family 291 403 7.3E-23 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK95_RS10410 b74c0057d7e6faac4e71611cbad4667a 117 SUPERFAMILY SSF54909 1 98 6.44E-9 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS28675 bd188ee50af8b8124375207055382eba 272 SUPERFAMILY SSF102215 5 255 7.72E-65 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK95_RS28675 bd188ee50af8b8124375207055382eba 272 Gene3D G3DSA:3.40.50.10310 4 257 4.0E-72 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK95_RS28675 bd188ee50af8b8124375207055382eba 272 Pfam PF02633 Creatinine amidohydrolase 10 251 5.1E-59 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK95_RS06760 09d59e2fc33475a61745c4d40f1db616 259 Gene3D G3DSA:3.40.50.150 6 204 5.6E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06760 09d59e2fc33475a61745c4d40f1db616 259 Pfam PF08241 Methyltransferase domain 45 136 1.5E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS06760 09d59e2fc33475a61745c4d40f1db616 259 SUPERFAMILY SSF53335 7 205 7.0E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS16910 4efbd438b25cb37e7085a391d5a404c8 311 Gene3D G3DSA:3.40.50.720 113 276 4.4E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16910 4efbd438b25cb37e7085a391d5a404c8 311 SUPERFAMILY SSF51735 100 277 2.42E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16910 4efbd438b25cb37e7085a391d5a404c8 311 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 276 2.0E-46 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS16910 4efbd438b25cb37e7085a391d5a404c8 311 Gene3D G3DSA:3.40.50.720 12 112 1.1E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS11820 06e2c659c5824339cde41b6a23cec1fd 185 SMART SM00507 81 131 3.5E-12 T 06-07-2017 IPR003615 HNH nuclease CAK95_RS11820 06e2c659c5824339cde41b6a23cec1fd 185 Pfam PF14279 HNH endonuclease 94 142 5.0E-14 T 06-07-2017 IPR029471 HNH endonuclease 5 CAK95_RS03330 fb388682613040816487ce8e31e708e5 377 Pfam PF13817 IS66 C-terminal element 324 361 3.5E-14 T 06-07-2017 CAK95_RS03330 fb388682613040816487ce8e31e708e5 377 Pfam PF03050 Transposase IS66 family 29 317 5.6E-94 T 06-07-2017 IPR004291 Transposase, IS66 CAK95_RS22490 8c5320b8d51edde71b4642b1a41fe59b 708 Pfam PF03030 Inorganic H+ pyrophosphatase 12 701 5.7E-260 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 CAK95_RS22490 8c5320b8d51edde71b4642b1a41fe59b 708 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 1 707 25.391 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 CAK95_RS22490 8c5320b8d51edde71b4642b1a41fe59b 708 PIRSF PIRSF001265 1 708 1.8E-245 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 CAK95_RS22490 8c5320b8d51edde71b4642b1a41fe59b 708 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 6 708 4.1E-275 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 CAK95_RS26840 3a6d3c1876e666ed3df25eb3c2e1536a 184 Gene3D G3DSA:2.60.120.10 4 182 7.2E-73 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS26840 3a6d3c1876e666ed3df25eb3c2e1536a 184 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 179 1.2E-66 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK95_RS26840 3a6d3c1876e666ed3df25eb3c2e1536a 184 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 181 5.5E-67 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK95_RS26840 3a6d3c1876e666ed3df25eb3c2e1536a 184 SUPERFAMILY SSF51182 3 182 4.09E-71 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS26840 3a6d3c1876e666ed3df25eb3c2e1536a 184 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 176 7.0E-60 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK95_RS11710 b8107d2a8620dbdb46b08e0eb03e6433 844 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 81 283 2.6E-20 T 06-07-2017 IPR010090 Phage tail tape measure protein CAK95_RS11710 b8107d2a8620dbdb46b08e0eb03e6433 844 Pfam PF10145 Phage-related minor tail protein 125 322 6.6E-21 T 06-07-2017 IPR010090 Phage tail tape measure protein CAK95_RS19850 3f16e5143eb64a8e13a3323db63b98ce 220 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 170 3.9E-13 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS19850 3f16e5143eb64a8e13a3323db63b98ce 220 SMART SM00702 1 171 6.9E-9 T 06-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CAK95_RS19850 3f16e5143eb64a8e13a3323db63b98ce 220 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 220 38.797 T 06-07-2017 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 CAK95_RS03745 b26bc6dc78dd5c6570d7bda816b06567 77 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS03745 b26bc6dc78dd5c6570d7bda816b06567 77 Gene3D G3DSA:3.30.70.20 12 70 1.9E-14 T 06-07-2017 CAK95_RS03745 b26bc6dc78dd5c6570d7bda816b06567 77 Pfam PF12838 4Fe-4S dicluster domain 19 67 7.0E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS03745 b26bc6dc78dd5c6570d7bda816b06567 77 SUPERFAMILY SSF54862 7 70 3.72E-14 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 119 131 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 164 177 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 47 56 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 74 85 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00097 Anthranilate synthase component II signature 99 107 5.7E-32 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.4E-6 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.4E-6 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 Pfam PF00117 Glutamine amidotransferase class-I 3 185 5.8E-51 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 Gene3D G3DSA:3.40.50.880 1 188 1.0E-65 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 SUPERFAMILY SSF52317 1 191 1.7E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.7E-14 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 7.7E-14 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 7.7E-14 T 06-07-2017 CAK95_RS23090 ded60e884f72008d03ca1b1b1649b0f2 201 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.2E-70 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK95_RS10210 bf02fb9bc2bfbc08b0fd300fa38e0e19 478 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 207 475 2.1E-49 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10210 bf02fb9bc2bfbc08b0fd300fa38e0e19 478 SUPERFAMILY SSF53850 201 430 2.14E-5 T 06-07-2017 CAK95_RS03135 fc8b97e4c9d64a5ebc8078d377251add 340 Pfam PF03864 Phage major capsid protein E 13 335 1.4E-95 T 06-07-2017 IPR005564 Major capsid protein GpE GO:0019028 CAK95_RS16005 7c558f47779a682749914ed7499834df 281 Gene3D G3DSA:3.40.50.300 14 251 1.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16005 7c558f47779a682749914ed7499834df 281 SUPERFAMILY SSF52540 17 257 2.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16005 7c558f47779a682749914ed7499834df 281 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16005 7c558f47779a682749914ed7499834df 281 SMART SM00382 44 235 1.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16005 7c558f47779a682749914ed7499834df 281 Pfam PF00005 ABC transporter 36 183 2.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16065 d8a8abb1e9739de992ba68dc1d86028e 240 SUPERFAMILY SSF48613 1 238 6.95E-62 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS16065 d8a8abb1e9739de992ba68dc1d86028e 240 Pfam PF03070 TENA/THI-4/PQQC family 8 218 3.8E-54 T 06-07-2017 IPR004305 Thiaminase-2/PQQC CAK95_RS16065 d8a8abb1e9739de992ba68dc1d86028e 240 Gene3D G3DSA:1.20.910.10 1 237 8.3E-100 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS16065 d8a8abb1e9739de992ba68dc1d86028e 240 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 1 238 2.7E-116 T 06-07-2017 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 CAK95_RS16065 d8a8abb1e9739de992ba68dc1d86028e 240 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 240 122.433 T 06-07-2017 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 CAK95_RS20405 260fc3f87497fdd0e5431fc721282e18 111 Pfam PF02625 XdhC and CoxI family 19 86 1.1E-25 T 06-07-2017 IPR003777 XdhC- CoxI CAK95_RS02155 25aeb3815debba00074d4cb350c53b47 235 SMART SM00382 30 215 2.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS02155 25aeb3815debba00074d4cb350c53b47 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS02155 25aeb3815debba00074d4cb350c53b47 235 SUPERFAMILY SSF52540 4 232 4.46E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02155 25aeb3815debba00074d4cb350c53b47 235 Gene3D G3DSA:3.40.50.300 4 232 1.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02155 25aeb3815debba00074d4cb350c53b47 235 Pfam PF00005 ABC transporter 23 164 2.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS03640 e2caf166c85e5b37318624949e612602 70 SUPERFAMILY SSF46955 14 63 1.21E-7 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS03640 e2caf166c85e5b37318624949e612602 70 Pfam PF12728 Helix-turn-helix domain 14 59 5.8E-10 T 06-07-2017 CAK95_RS03640 e2caf166c85e5b37318624949e612602 70 Gene3D G3DSA:1.10.10.10 14 63 6.6E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13990 985e88d0b0000c7a5ddc50eff732a757 325 Pfam PF02915 Rubrerythrin 18 154 1.0E-31 T 06-07-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CAK95_RS13990 985e88d0b0000c7a5ddc50eff732a757 325 PIRSF PIRSF035918 2 325 4.2E-173 T 06-07-2017 IPR017040 Uncharacterised conserved protein UCP035918 , rubrerythrin/DUF125-related CAK95_RS13990 985e88d0b0000c7a5ddc50eff732a757 325 Gene3D G3DSA:1.20.1260.10 14 154 4.9E-28 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS13990 985e88d0b0000c7a5ddc50eff732a757 325 SUPERFAMILY SSF47240 9 154 1.55E-32 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Gene3D G3DSA:3.50.50.60 332 392 2.4E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Gene3D G3DSA:3.50.50.60 1 217 2.4E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Gene3D G3DSA:1.20.58.100 421 527 2.3E-25 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Pfam PF02910 Fumarate reductase flavoprotein C-term 429 528 9.3E-21 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.6E-5 T 06-07-2017 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 338 360 1.6E-5 T 06-07-2017 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 PIRSF PIRSF000171 1 539 1.8E-48 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 SUPERFAMILY SSF46977 420 539 1.7E-31 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Gene3D G3DSA:3.90.700.10 218 331 6.7E-14 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 Pfam PF00890 FAD binding domain 1 373 2.1E-56 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 SUPERFAMILY SSF56425 212 336 1.45E-16 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 SUPERFAMILY SSF51905 1 229 2.16E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS26740 07e0b557f226a92273ac7c95ff443cba 547 SUPERFAMILY SSF51905 339 390 2.16E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS02835 c15cbfd21c1503135f1084a5406eb4ca 182 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 92 3.0E-15 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS02835 c15cbfd21c1503135f1084a5406eb4ca 182 SUPERFAMILY SSF50475 5 143 3.44E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS02835 c15cbfd21c1503135f1084a5406eb4ca 182 Gene3D G3DSA:2.30.110.10 6 142 1.4E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 SUPERFAMILY SSF52317 1 229 7.18E-75 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 PIRSF PIRSF001586 1 232 5.5E-88 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 Gene3D G3DSA:3.40.50.880 1 227 3.4E-38 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 228 8.9E-95 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 227 43.849 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 213 2.9E-42 T 06-07-2017 CAK95_RS26515 6dda2aa96dee9e04cd1656bd33e09cdd 233 SMART SM01211 1 229 1.3E-132 T 06-07-2017 CAK95_RS05580 3b4c497a99434e2bb5d6aa2ecff4d855 391 Pfam PF00155 Aminotransferase class I and II 43 385 7.4E-60 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS05580 3b4c497a99434e2bb5d6aa2ecff4d855 391 Gene3D G3DSA:3.40.640.10 47 259 4.1E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS05580 3b4c497a99434e2bb5d6aa2ecff4d855 391 Gene3D G3DSA:3.90.1150.10 260 390 3.2E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS05580 3b4c497a99434e2bb5d6aa2ecff4d855 391 SUPERFAMILY SSF53383 25 390 5.39E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 SMART SM00347 55 155 3.5E-24 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 94 128 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 Pfam PF01047 MarR family 62 119 1.3E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 1.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 111 1.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 131 1.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 145 165 1.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 Gene3D G3DSA:1.10.10.10 26 169 1.4E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07065 34b9c357ef4b872c736c2422c1440617 181 SUPERFAMILY SSF46785 31 168 2.98E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 SUPERFAMILY SSF53901 2 251 4.01E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 Gene3D G3DSA:3.40.47.10 2 255 4.7E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 2.2E-27 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 SUPERFAMILY SSF53901 213 401 2.33E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.3E-37 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 SMART SM00825 Beta-ketoacyl synthase 4 405 1.1E-10 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 Gene3D G3DSA:3.40.47.10 261 403 6.9E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS09115 f9859cae5cfe0d6a1bdebbd2f3820624 405 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 SUPERFAMILY SSF53383 90 449 8.29E-67 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 SMART SM00345 18 77 1.8E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 SUPERFAMILY SSF46785 11 85 1.91E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 Pfam PF00155 Aminotransferase class I and II 93 442 2.2E-18 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 Gene3D G3DSA:3.40.640.10 127 344 5.3E-54 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS04610 8fae306c05fb66f3e39e44432f46fcb2 458 Gene3D G3DSA:1.10.10.10 12 79 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25630 dbb5f598758535364cdfaf397507aa3d 184 SUPERFAMILY SSF53597 6 164 8.64E-17 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS25630 dbb5f598758535364cdfaf397507aa3d 184 Gene3D G3DSA:3.40.430.10 8 157 7.3E-14 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 Gene3D G3DSA:3.10.180.10 156 293 1.1E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 SUPERFAMILY SSF54593 4 271 3.04E-43 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 8 313 1.3E-105 T 06-07-2017 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 Gene3D G3DSA:3.10.180.10 7 155 3.2E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 271 9.8E-16 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS17235 b00f31f94b102743e4c0d83fffa775d7 321 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 120 6.6E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 SUPERFAMILY SSF51735 1 160 1.23E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 282 1.0E-16 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 SUPERFAMILY SSF48179 161 284 2.83E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 Gene3D G3DSA:3.40.50.720 2 161 2.6E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 PIRSF PIRSF000103 1 289 1.5E-51 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 Gene3D G3DSA:1.10.1040.10 163 285 7.0E-24 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS00350 bed63c31758512f0d3c8e90dbb118021 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 160 2.0E-28 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Gene3D G3DSA:3.40.50.980 31 195 3.2E-16 T 06-07-2017 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Gene3D G3DSA:3.30.300.30 442 539 3.3E-23 T 06-07-2017 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Pfam PF00501 AMP-binding enzyme 40 445 1.4E-67 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 530 3.2E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Gene3D G3DSA:3.40.50.980 196 359 3.3E-27 T 06-07-2017 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 Gene3D G3DSA:2.30.38.10 360 436 3.1E-20 T 06-07-2017 CAK95_RS19290 2a0612004fc5f04be7351fb3336ef638 601 SUPERFAMILY SSF56801 30 537 1.13E-106 T 06-07-2017 CAK95_RS07285 b4fd859582bb66e31e345c7d38e7b01b 316 Pfam PF07987 Domain of unkown function (DUF1775) 11 156 4.9E-49 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria CAK95_RS07285 b4fd859582bb66e31e345c7d38e7b01b 316 Pfam PF04314 Protein of unknown function (DUF461) 183 292 5.4E-38 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAK95_RS07285 b4fd859582bb66e31e345c7d38e7b01b 316 SUPERFAMILY SSF110087 167 301 3.01E-46 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAK95_RS07285 b4fd859582bb66e31e345c7d38e7b01b 316 PIRSF PIRSF037139 1 316 2.3E-96 T 06-07-2017 IPR021174 Uncharacterised conserved protein UCP037139 CAK95_RS20470 b137a09bd83f89fbcd50dc1d014b4fb5 161 Gene3D G3DSA:3.40.630.30 7 145 1.9E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS20470 b137a09bd83f89fbcd50dc1d014b4fb5 161 Pfam PF00583 Acetyltransferase (GNAT) family 60 135 8.1E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS20470 b137a09bd83f89fbcd50dc1d014b4fb5 161 SUPERFAMILY SSF55729 7 145 3.66E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS24240 7f35b4fab406e67ca72084c00983c473 304 SMART SM00014 123 246 5.6E-9 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS24240 7f35b4fab406e67ca72084c00983c473 304 Gene3D G3DSA:1.20.144.10 87 253 6.7E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS24240 7f35b4fab406e67ca72084c00983c473 304 Pfam PF01569 PAP2 superfamily 122 252 7.6E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS24240 7f35b4fab406e67ca72084c00983c473 304 SUPERFAMILY SSF48317 37 256 1.31E-29 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS28710 fc384e42c02e7c8df4b7201441e8464a 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 352 2.7E-25 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS28715 823f558a4d7ff84273ea82a661da66f2 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 289 1.5E-44 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS00420 90626bc35ceea1d5831f7b9fb08aa51c 261 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 173 1.6E-41 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS00420 90626bc35ceea1d5831f7b9fb08aa51c 261 Gene3D G3DSA:3.30.43.10 1 53 6.9E-13 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS00420 90626bc35ceea1d5831f7b9fb08aa51c 261 Gene3D G3DSA:3.30.465.10 57 172 2.1E-29 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS00420 90626bc35ceea1d5831f7b9fb08aa51c 261 SUPERFAMILY SSF56176 5 172 5.23E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS17260 4f14f1109993093b4a5368007dfb7de2 228 Gene3D G3DSA:3.40.50.150 38 220 1.7E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17260 4f14f1109993093b4a5368007dfb7de2 228 Pfam PF06080 Protein of unknown function (DUF938) 22 221 2.9E-64 T 06-07-2017 IPR010342 Protein of unknown function DUF938 CAK95_RS17260 4f14f1109993093b4a5368007dfb7de2 228 SUPERFAMILY SSF53335 25 215 3.41E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 SUPERFAMILY SSF51726 2 339 7.46E-99 T 06-07-2017 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 18 27 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 5 339 5.6E-119 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 2 340 44.079 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 137 153 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 Gene3D G3DSA:3.20.20.210 2 339 2.4E-119 T 06-07-2017 CAK95_RS08075 c8899bd0ab1de581317de673f46d9aa6 340 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 2 339 9.2E-107 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 785 893 8.3E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Pfam PF00072 Response regulator receiver domain 920 1030 3.4E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SMART SM00387 785 896 3.7E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 PRINTS PR00344 Bacterial sensor protein C-terminal signature 821 835 1.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 PRINTS PR00344 Bacterial sensor protein C-terminal signature 880 893 1.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 PRINTS PR00344 Bacterial sensor protein C-terminal signature 856 874 1.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 PRINTS PR00344 Bacterial sensor protein C-terminal signature 839 849 1.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SUPERFAMILY SSF55874 728 892 3.27E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SUPERFAMILY SSF47384 659 739 1.96E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Gene3D G3DSA:3.40.50.2300 917 1036 5.8E-32 T 06-07-2017 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Gene3D G3DSA:3.30.565.10 739 894 1.1E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Pfam PF00512 His Kinase A (phospho-acceptor) domain 673 738 1.9E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SUPERFAMILY SSF52172 918 1040 9.25E-33 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SMART SM00448 918 1030 4.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 SMART SM00388 672 738 1.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS28520 05601411e115b4e6a7fd3a0aa4f5dc92 1126 Gene3D G3DSA:1.10.287.130 667 734 1.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 200 1.5E-51 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 SUPERFAMILY SSF52540 1 210 4.54E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 Pfam PF02223 Thymidylate kinase 8 200 3.0E-48 T 06-07-2017 CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 29.243 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 Gene3D G3DSA:3.40.50.300 2 208 2.1E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23325 29652fdacee658dcfe3d9048797710f6 222 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 06-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Gene3D G3DSA:3.40.50.980 59 251 1.2E-34 T 06-07-2017 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Gene3D G3DSA:3.30.300.30 507 610 3.0E-22 T 06-07-2017 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 246 257 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Gene3D G3DSA:3.40.50.980 252 412 1.5E-24 T 06-07-2017 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Gene3D G3DSA:2.30.38.10 427 504 1.6E-10 T 06-07-2017 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 SUPERFAMILY SSF56801 9 631 6.8E-153 T 06-07-2017 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Pfam PF13193 AMP-binding enzyme C-terminal domain 520 598 3.0E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Pfam PF00501 AMP-binding enzyme 70 510 1.0E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS04315 9a17d05310f7e6979eb7a63baa98817e 639 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 9 63 3.4E-19 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAK95_RS05690 83f25e427d3e2b3036ed722136493537 198 Pfam PF02630 SCO1/SenC 40 183 5.0E-46 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05690 83f25e427d3e2b3036ed722136493537 198 SUPERFAMILY SSF52833 42 198 4.17E-53 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS05690 83f25e427d3e2b3036ed722136493537 198 Gene3D G3DSA:3.40.30.10 17 197 2.8E-61 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 SMART SM00849 12 171 2.1E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 Gene3D G3DSA:3.40.250.10 229 343 1.0E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 Pfam PF00753 Metallo-beta-lactamase superfamily 11 171 1.6E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 SUPERFAMILY SSF52821 218 344 2.23E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 Pfam PF00581 Rhodanese-like domain 244 339 7.9E-12 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 SUPERFAMILY SSF56281 1 219 2.8E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 SMART SM00450 238 342 4.0E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS24195 533cc7aac4f9727e42bf98971c0d4e29 345 Gene3D G3DSA:3.60.15.10 4 217 3.9E-57 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15335 8872ad638685e2580aed16a700310646 113 SUPERFAMILY SSF101801 36 112 2.88E-23 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS15335 8872ad638685e2580aed16a700310646 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 39 55 1.8E-25 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS15335 8872ad638685e2580aed16a700310646 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 72 85 1.8E-25 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS15335 8872ad638685e2580aed16a700310646 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 56 72 1.8E-25 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS15335 8872ad638685e2580aed16a700310646 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 85 100 1.8E-25 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAK95_RS15335 8872ad638685e2580aed16a700310646 113 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 37 111 2.8E-30 T 06-07-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAK95_RS15335 8872ad638685e2580aed16a700310646 113 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 39 109 3.9E-25 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAK95_RS15335 8872ad638685e2580aed16a700310646 113 Gene3D G3DSA:2.30.330.10 29 111 2.2E-31 T 06-07-2017 CAK95_RS21950 67bfea668f5a1f38e3d8258082788fa2 129 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 35 124 28.576 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CAK95_RS21950 67bfea668f5a1f38e3d8258082788fa2 129 SUPERFAMILY SSF54736 44 128 1.83E-32 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS21950 67bfea668f5a1f38e3d8258082788fa2 129 Gene3D G3DSA:3.30.1390.10 28 128 3.9E-46 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK95_RS21950 67bfea668f5a1f38e3d8258082788fa2 129 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 46 124 2.4E-34 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 ProSitePatterns PS00737 Thiolases signature 2. 358 374 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 410 4.9E-122 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Gene3D G3DSA:3.40.47.10 296 411 1.1E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Gene3D G3DSA:3.40.47.10 153 203 1.1E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 PIRSF PIRSF000429 9 413 6.9E-118 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 SUPERFAMILY SSF53901 13 288 3.76E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Pfam PF00108 Thiolase, N-terminal domain 16 281 6.6E-61 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 SUPERFAMILY SSF53901 290 411 4.73E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Pfam PF02803 Thiolase, C-terminal domain 290 410 7.0E-49 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 ProSitePatterns PS00099 Thiolases active site. 393 406 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Gene3D G3DSA:3.40.47.10 14 134 8.0E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS06195 b5d37f805d7c9a808e3eb52b1469106d 417 Gene3D G3DSA:3.40.47.10 204 295 8.0E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS10725 1c97f79c168993beb815639b5b7154a0 652 Pfam PF04862 Protein of unknown function (DUF642) 441 588 1.9E-6 T 06-07-2017 IPR006946 Domain of unknown function DUF642 CAK95_RS10725 1c97f79c168993beb815639b5b7154a0 652 SUPERFAMILY SSF49785 438 590 8.5E-6 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK95_RS10725 1c97f79c168993beb815639b5b7154a0 652 Gene3D G3DSA:2.60.40.1560 351 424 3.4E-4 T 06-07-2017 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 Pfam PF05199 GMC oxidoreductase 393 532 1.9E-39 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 Gene3D G3DSA:3.50.50.60 474 539 4.1E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 Gene3D G3DSA:3.50.50.60 193 319 4.1E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 Gene3D G3DSA:3.50.50.60 9 132 4.1E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 SUPERFAMILY SSF51905 9 289 9.71E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 SUPERFAMILY SSF51905 477 539 9.71E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 260 274 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 88 111 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 PIRSF PIRSF000137 1 542 6.9E-145 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 SUPERFAMILY SSF54373 296 481 8.34E-60 T 06-07-2017 CAK95_RS06970 df0c536f6788864c443539279df9b64f 542 Pfam PF00732 GMC oxidoreductase 11 301 1.3E-82 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS20690 c1ea62ed26835abc5909ae28d3f8f572 82 Pfam PF10276 Zinc-finger domain 23 58 1.4E-10 T 06-07-2017 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS20690 c1ea62ed26835abc5909ae28d3f8f572 82 Gene3D G3DSA:2.60.260.40 1 80 1.8E-29 T 06-07-2017 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 Gene3D G3DSA:3.30.1330.60 46 157 7.1E-36 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 56 158 3.7E-42 T 06-07-2017 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 PRINTS PR01021 OMPA domain signature 104 120 1.6E-15 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 PRINTS PR01021 OMPA domain signature 89 104 1.6E-15 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 PRINTS PR01021 OMPA domain signature 59 81 1.6E-15 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 ProSitePatterns PS01068 OmpA-like domain. 91 135 - T 06-07-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 SUPERFAMILY SSF103088 47 159 1.19E-35 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS03990 5aea129e3f1d2507a1d73e6b048d63a7 163 Pfam PF00691 OmpA family 58 153 1.9E-23 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS04910 35a5b73fafae735b6a3aad1f9cb95293 248 PIRSF PIRSF015736 1 248 2.6E-48 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAK95_RS26420 efe39d2ae9c33ad4d39d9ba27744d62a 463 SUPERFAMILY SSF52129 16 249 1.26E-45 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS26420 efe39d2ae9c33ad4d39d9ba27744d62a 463 Pfam PF00656 Caspase domain 30 246 6.5E-30 T 06-07-2017 CAK95_RS26420 efe39d2ae9c33ad4d39d9ba27744d62a 463 Gene3D G3DSA:3.40.50.1460 29 249 3.7E-14 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 Gene3D G3DSA:3.40.390.30 30 165 8.3E-45 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 125 135 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 SUPERFAMILY SSF55486 23 165 8.55E-42 T 06-07-2017 CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 51 155 4.8E-34 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 Pfam PF02130 Uncharacterized protein family UPF0054 30 154 2.2E-36 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK95_RS09215 9cd650557015e79d30559515225ce0a5 168 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 15 159 22.182 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Gene3D G3DSA:1.10.540.10 2 119 8.5E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 7.8E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 SUPERFAMILY SSF47203 229 378 5.15E-55 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 SUPERFAMILY SSF56645 2 242 2.49E-66 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 5.2E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Gene3D G3DSA:1.20.140.10 220 378 1.4E-64 T 06-07-2017 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 1.5E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS14965 7bbbaad489072e2ef9d4bd54c65d4ffe 383 Gene3D G3DSA:2.40.110.10 122 219 8.7E-33 T 06-07-2017 CAK95_RS11185 1cec656ddb2e03b6aee042f1c91d58bf 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 322 1.4E-96 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK95_RS11185 1cec656ddb2e03b6aee042f1c91d58bf 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 327 3.4E-48 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK95_RS11185 1cec656ddb2e03b6aee042f1c91d58bf 333 PIRSF PIRSF000267 2 333 1.2E-89 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK95_RS27750 8c2c79a7fe236f388455e42316358cd9 403 Gene3D G3DSA:3.40.50.2300 25 153 2.4E-46 T 06-07-2017 CAK95_RS27750 8c2c79a7fe236f388455e42316358cd9 403 Gene3D G3DSA:3.40.50.2300 293 358 2.4E-46 T 06-07-2017 CAK95_RS27750 8c2c79a7fe236f388455e42316358cd9 403 Pfam PF13458 Periplasmic binding protein 30 373 1.2E-73 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS27750 8c2c79a7fe236f388455e42316358cd9 403 SUPERFAMILY SSF53822 29 383 1.31E-86 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS14035 134c186d9cc7a7b8dda5e6ae9178a644 322 PIRSF PIRSF017082 1 322 2.3E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14035 134c186d9cc7a7b8dda5e6ae9178a644 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 7.0E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14035 134c186d9cc7a7b8dda5e6ae9178a644 322 SUPERFAMILY SSF53850 110 276 3.69E-8 T 06-07-2017 CAK95_RS11340 3f7bb992614fb122280bdc09fcd18a43 143 Gene3D G3DSA:1.10.150.130 2 46 2.5E-5 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK95_RS11340 3f7bb992614fb122280bdc09fcd18a43 143 Gene3D G3DSA:1.10.443.10 63 142 3.4E-9 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS11340 3f7bb992614fb122280bdc09fcd18a43 143 SUPERFAMILY SSF56349 3 142 2.94E-23 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS11340 3f7bb992614fb122280bdc09fcd18a43 143 Pfam PF00589 Phage integrase family 59 140 1.4E-7 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 Gene3D G3DSA:3.40.50.880 2 214 1.1E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 214 34.627 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 Pfam PF00117 Glutamine amidotransferase class-I 6 211 7.3E-20 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 213 5.2E-62 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 PIRSF PIRSF000495 1 216 3.7E-68 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK95_RS07995 affa56a316e3c7b0ae6276fc2414eb24 216 SUPERFAMILY SSF52317 5 205 9.59E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS24785 6a26fb2a5529db5ac24cdf2a21c3a68f 405 Pfam PF00155 Aminotransferase class I and II 31 383 7.4E-55 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS24785 6a26fb2a5529db5ac24cdf2a21c3a68f 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAK95_RS24785 6a26fb2a5529db5ac24cdf2a21c3a68f 405 Gene3D G3DSA:3.90.1150.10 258 389 4.7E-44 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS24785 6a26fb2a5529db5ac24cdf2a21c3a68f 405 Gene3D G3DSA:3.40.640.10 45 257 3.3E-59 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS24785 6a26fb2a5529db5ac24cdf2a21c3a68f 405 SUPERFAMILY SSF53383 4 389 2.09E-105 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 Gene3D G3DSA:3.40.50.300 342 587 1.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 SMART SM00382 367 567 4.0E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 SUPERFAMILY SSF52540 343 589 1.04E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 Pfam PF00005 ABC transporter 358 518 1.3E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 568 589 3.0E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS14330 ac8da2e8d44aefae19f7383da80adf8b 599 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 294 8.6E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS24470 8d07efbae10e03ad930a79e9a615668b 424 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 50 393 1.1E-70 T 06-07-2017 IPR006427 Phage portal protein, HK97 CAK95_RS24470 8d07efbae10e03ad930a79e9a615668b 424 Pfam PF04860 Phage portal protein 60 387 9.4E-85 T 06-07-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Gene3D G3DSA:3.30.1360.120 17 49 1.4E-20 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Gene3D G3DSA:3.30.1360.120 123 217 1.4E-20 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 284 403 8.5E-12 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Gene3D G3DSA:2.40.30.110 343 402 3.9E-6 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 SUPERFAMILY SSF101790 342 407 2.29E-7 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 SUPERFAMILY SSF103025 264 295 1.31E-45 T 06-07-2017 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 SUPERFAMILY SSF103025 17 233 1.31E-45 T 06-07-2017 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Gene3D G3DSA:3.30.70.1400 50 98 2.6E-8 T 06-07-2017 CAK95_RS04385 fdcb5ff3a352f26ccb930423f8019be6 425 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 225 2.7E-34 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK95_RS22000 407fb7db24da28e6a1159a49d795cbdf 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 95 1.6E-13 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAK95_RS22000 407fb7db24da28e6a1159a49d795cbdf 241 SUPERFAMILY SSF51695 12 234 1.31E-40 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS22000 407fb7db24da28e6a1159a49d795cbdf 241 Gene3D G3DSA:3.20.20.190 12 230 6.1E-39 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS26335 178da6cc882416cc5ea173d51de254da 231 Pfam PF01728 FtsJ-like methyltransferase 49 227 1.7E-53 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CAK95_RS26335 178da6cc882416cc5ea173d51de254da 231 Gene3D G3DSA:3.40.50.150 11 229 7.9E-71 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26335 178da6cc882416cc5ea173d51de254da 231 SUPERFAMILY SSF53335 48 228 1.34E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26335 178da6cc882416cc5ea173d51de254da 231 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 29 227 28.387 T 06-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CAK95_RS26335 178da6cc882416cc5ea173d51de254da 231 PIRSF PIRSF005461 14 231 5.9E-71 T 06-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CAK95_RS06540 0b578b26629566de540f7807f4386765 261 Gene3D G3DSA:3.90.226.10 5 200 5.1E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06540 0b578b26629566de540f7807f4386765 261 SUPERFAMILY SSF52096 4 260 3.95E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS06540 0b578b26629566de540f7807f4386765 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS06540 0b578b26629566de540f7807f4386765 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 261 1.7E-58 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS06540 0b578b26629566de540f7807f4386765 261 Gene3D G3DSA:1.10.12.10 203 260 5.9E-14 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.7E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.7E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.7E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 231 4.4E-50 T 06-07-2017 CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 SUPERFAMILY SSF51735 6 238 5.1E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 190 1.2E-4 T 06-07-2017 CAK95_RS10645 ba4f61ee36668550c999227263f6974f 246 Gene3D G3DSA:3.40.50.720 5 241 5.4E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13850 14a1872f153195636d3eec0d6bf51a88 232 Pfam PF13280 WYL domain 139 227 3.0E-15 T 06-07-2017 IPR026881 WYL domain CAK95_RS13850 14a1872f153195636d3eec0d6bf51a88 232 Pfam PF08279 HTH domain 6 59 5.7E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 CAK95_RS13850 14a1872f153195636d3eec0d6bf51a88 232 SUPERFAMILY SSF46785 1 61 5.93E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13850 14a1872f153195636d3eec0d6bf51a88 232 Gene3D G3DSA:1.10.10.10 1 63 7.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17845 579701b166c7a159495831317b19d7bd 265 SUPERFAMILY SSF53613 2 264 1.08E-82 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS17845 579701b166c7a159495831317b19d7bd 265 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 261 1.8E-103 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK95_RS17845 579701b166c7a159495831317b19d7bd 265 Pfam PF08543 Phosphomethylpyrimidine kinase 12 259 3.3E-98 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAK95_RS17845 579701b166c7a159495831317b19d7bd 265 Gene3D G3DSA:3.40.1190.20 3 262 6.7E-106 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS05395 11abded74acbf2fd62dad420457f196d 298 SUPERFAMILY SSF103481 209 296 1.44E-8 T 06-07-2017 CAK95_RS05395 11abded74acbf2fd62dad420457f196d 298 SUPERFAMILY SSF103481 44 145 5.89E-11 T 06-07-2017 CAK95_RS05395 11abded74acbf2fd62dad420457f196d 298 Pfam PF00892 EamA-like transporter family 159 294 1.4E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS05395 11abded74acbf2fd62dad420457f196d 298 Pfam PF00892 EamA-like transporter family 13 142 9.6E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS22940 f800d2da57fb1bfe4ba8d29872c4912b 190 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 186 90.486 T 06-07-2017 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 CAK95_RS22940 f800d2da57fb1bfe4ba8d29872c4912b 190 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 20 181 4.6E-59 T 06-07-2017 IPR020761 Uncharacterised protein family UPF0114, bacteria CAK95_RS22940 f800d2da57fb1bfe4ba8d29872c4912b 190 Pfam PF03350 Uncharacterized protein family, UPF0114 22 138 6.0E-41 T 06-07-2017 IPR005134 Uncharacterised protein family UPF0114 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 SUPERFAMILY SSF63867 344 419 1.7E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 SMART SM00852 191 334 3.2E-41 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 264 297 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Pfam PF00994 Probable molybdopterin binding domain 192 332 8.0E-28 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 SUPERFAMILY SSF53218 186 337 4.45E-39 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Pfam PF03454 MoeA C-terminal region (domain IV) 348 418 5.5E-15 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Pfam PF03453 MoeA N-terminal region (domain I and II) 30 178 6.2E-34 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Gene3D G3DSA:3.90.105.10 35 58 3.7E-17 T 06-07-2017 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Gene3D G3DSA:3.90.105.10 153 173 3.7E-17 T 06-07-2017 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Gene3D G3DSA:3.40.980.10 174 347 9.1E-56 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Gene3D G3DSA:2.170.190.11 59 152 1.9E-28 T 06-07-2017 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 188 330 9.1E-27 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 Gene3D G3DSA:2.40.340.10 348 419 3.9E-16 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06575 a1ef79b92920937213775e48ee94af35 424 SUPERFAMILY SSF63882 15 186 4.06E-53 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 SMART SM00382 46 246 2.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 Gene3D G3DSA:3.40.50.300 21 266 7.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 SUPERFAMILY SSF52540 21 268 6.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 268 4.4E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS00380 1921b57106b38a7e1ae32d2a0d707756 277 Pfam PF00005 ABC transporter 37 197 1.6E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 Gene3D G3DSA:1.10.357.10 82 217 6.9E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 Pfam PF13305 WHG domain 107 193 4.1E-16 T 06-07-2017 IPR025996 WHG domain CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 80 3.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 SUPERFAMILY SSF48498 101 207 2.0E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 Gene3D G3DSA:1.10.10.60 21 81 8.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS07710 876c3352364b3f167ca3fca5cb62d922 222 SUPERFAMILY SSF46689 24 95 7.18E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS00660 8d7ef2bd8caa3c3c6b79ea04b2e7d135 291 SUPERFAMILY SSF88713 5 288 4.89E-54 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS00660 8d7ef2bd8caa3c3c6b79ea04b2e7d135 291 Gene3D G3DSA:3.20.20.370 6 289 1.6E-56 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS00660 8d7ef2bd8caa3c3c6b79ea04b2e7d135 291 Pfam PF01522 Polysaccharide deacetylase 69 174 7.4E-10 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS14335 bb0326f961374c8dee73ff69d4d453e5 247 Pfam PF00005 ABC transporter 24 168 5.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14335 bb0326f961374c8dee73ff69d4d453e5 247 SMART SM00382 32 221 2.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14335 bb0326f961374c8dee73ff69d4d453e5 247 SUPERFAMILY SSF52540 6 242 4.37E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14335 bb0326f961374c8dee73ff69d4d453e5 247 Gene3D G3DSA:3.40.50.300 5 238 1.1E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14335 bb0326f961374c8dee73ff69d4d453e5 247 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS17750 d54e0bfb12ebaf49e037e0295f877dce 384 SUPERFAMILY SSF53756 22 372 1.4E-61 T 06-07-2017 CAK95_RS17750 d54e0bfb12ebaf49e037e0295f877dce 384 Pfam PF13477 Glycosyl transferase 4-like 8 151 4.3E-15 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS17750 d54e0bfb12ebaf49e037e0295f877dce 384 Pfam PF13692 Glycosyl transferases group 1 197 338 5.8E-26 T 06-07-2017 CAK95_RS17750 d54e0bfb12ebaf49e037e0295f877dce 384 Gene3D G3DSA:3.40.50.2000 145 351 2.7E-23 T 06-07-2017 CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 Pfam PF04055 Radical SAM superfamily 173 332 4.2E-9 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 Gene3D G3DSA:3.80.30.20 167 368 3.0E-29 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 SMART SM00729 169 378 1.1E-4 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 Pfam PF13282 Domain of unknown function (DUF4070) 361 516 6.6E-30 T 06-07-2017 IPR025274 Domain of unknown function DUF4070 CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 Pfam PF02310 B12 binding domain 32 130 1.9E-7 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS26790 410d12907ed8a56e56be988529ea37e0 539 SUPERFAMILY SSF102114 153 373 1.57E-23 T 06-07-2017 CAK95_RS06905 fcc00a96ea1e18eb142e44ea6b4eecf4 131 Pfam PF00085 Thioredoxin 33 129 5.5E-14 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK95_RS06905 fcc00a96ea1e18eb142e44ea6b4eecf4 131 Gene3D G3DSA:3.40.30.10 30 129 2.1E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS06905 fcc00a96ea1e18eb142e44ea6b4eecf4 131 ProSitePatterns PS00194 Thioredoxin family active site. 47 65 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS06905 fcc00a96ea1e18eb142e44ea6b4eecf4 131 SUPERFAMILY SSF52833 26 130 1.08E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12980 e31dd4cb48cfc7bfd83ceecf8b395973 408 SUPERFAMILY SSF103473 10 398 3.79E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS12980 e31dd4cb48cfc7bfd83ceecf8b395973 408 Gene3D G3DSA:1.20.1250.20 220 399 2.8E-22 T 06-07-2017 CAK95_RS12980 e31dd4cb48cfc7bfd83ceecf8b395973 408 Gene3D G3DSA:1.20.1250.20 25 203 1.6E-20 T 06-07-2017 CAK95_RS12980 e31dd4cb48cfc7bfd83ceecf8b395973 408 Pfam PF07690 Major Facilitator Superfamily 26 306 6.8E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS21610 29dd4cae44f540959474b949692b3e6f 123 Gene3D G3DSA:1.10.10.10 2 106 6.9E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21610 29dd4cae44f540959474b949692b3e6f 123 SUPERFAMILY SSF46785 7 118 2.84E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS21610 29dd4cae44f540959474b949692b3e6f 123 Pfam PF01638 HxlR-like helix-turn-helix 20 105 1.7E-22 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS28395 97af9b5f2ba2882dcd54db76e7836a71 464 SUPERFAMILY SSF52467 294 464 3.01E-75 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS28395 97af9b5f2ba2882dcd54db76e7836a71 464 PIRSF PIRSF000204 1 464 7.0E-214 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK95_RS28395 97af9b5f2ba2882dcd54db76e7836a71 464 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 462 2.8E-191 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK95_RS28395 97af9b5f2ba2882dcd54db76e7836a71 464 Gene3D G3DSA:3.40.50.1220 289 464 1.0E-86 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS14570 367a9a2677a1f41efaf7a0ac9e84ab49 176 SUPERFAMILY SSF101738 4 117 2.35E-45 T 06-07-2017 IPR007481 Stringent starvation protein B CAK95_RS14570 367a9a2677a1f41efaf7a0ac9e84ab49 176 Gene3D G3DSA:2.30.30.220 2 117 2.9E-54 T 06-07-2017 IPR007481 Stringent starvation protein B CAK95_RS14570 367a9a2677a1f41efaf7a0ac9e84ab49 176 Pfam PF04386 Stringent starvation protein B 11 168 1.3E-52 T 06-07-2017 IPR007481 Stringent starvation protein B CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 SUPERFAMILY SSF100879 271 371 5.89E-26 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Gene3D G3DSA:1.10.150.20 201 267 1.6E-18 T 06-07-2017 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Hamap MF_01113 DNA polymerase IV [dinB]. 35 400 34.619 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Gene3D G3DSA:3.30.70.270 98 196 4.1E-27 T 06-07-2017 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Pfam PF00817 impB/mucB/samB family 41 187 3.7E-46 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Pfam PF11799 impB/mucB/samB family C-terminal domain 269 376 1.2E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 Gene3D G3DSA:3.30.1490.100 274 376 4.8E-32 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK95_RS22015 b82ad28e3da665126f103ab8f29e936b 422 SUPERFAMILY SSF56672 38 267 1.16E-77 T 06-07-2017 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 Pfam PF13180 PDZ domain 147 211 7.4E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 145 379 1.7E-48 T 06-07-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 SMART SM00228 138 206 2.5E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 Gene3D G3DSA:2.30.42.10 116 215 1.1E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 Pfam PF02163 Peptidase family M50 21 366 2.9E-80 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAK95_RS22990 9c6870b217af740df4cfc4fe49ed0771 381 SUPERFAMILY SSF50156 120 214 3.02E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS08640 1c18ce26057c9c809066f2b598b912aa 299 SUPERFAMILY SSF103481 167 189 1.44E-8 T 06-07-2017 CAK95_RS08640 1c18ce26057c9c809066f2b598b912aa 299 SUPERFAMILY SSF103481 226 293 1.44E-8 T 06-07-2017 CAK95_RS08640 1c18ce26057c9c809066f2b598b912aa 299 SUPERFAMILY SSF103481 51 149 7.06E-6 T 06-07-2017 CAK95_RS08640 1c18ce26057c9c809066f2b598b912aa 299 Pfam PF00892 EamA-like transporter family 16 148 2.1E-7 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS08640 1c18ce26057c9c809066f2b598b912aa 299 Pfam PF00892 EamA-like transporter family 162 293 8.1E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS27800 f7e744a8cec45f7e091035347f2fb4c0 200 Gene3D G3DSA:3.20.20.140 9 154 1.2E-34 T 06-07-2017 CAK95_RS27800 f7e744a8cec45f7e091035347f2fb4c0 200 Pfam PF04909 Amidohydrolase 15 152 6.1E-18 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS27800 f7e744a8cec45f7e091035347f2fb4c0 200 SUPERFAMILY SSF51556 15 152 7.48E-29 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS18790 168086022e5bda5b28d59444379678a2 344 Gene3D G3DSA:2.150.10.10 121 336 2.2E-15 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 5 226 1.2E-93 T 06-07-2017 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 Gene3D G3DSA:3.40.50.300 3 223 2.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 SUPERFAMILY SSF52540 4 223 7.31E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 Pfam PF00005 ABC transporter 28 181 4.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27900 139b73ab67961f6337a9327da9a199a9 232 SMART SM00382 36 229 5.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16735 b24484184676605f85b52d027be954db 98 Pfam PF00034 Cytochrome c 22 98 2.2E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16735 b24484184676605f85b52d027be954db 98 SUPERFAMILY SSF46626 4 98 2.96E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16735 b24484184676605f85b52d027be954db 98 Gene3D G3DSA:1.10.760.10 3 98 1.5E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS10655 64537aa877a2ad08585d4cd9bf0d40e0 358 Pfam PF02615 Malate/L-lactate dehydrogenase 13 338 7.2E-108 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS10655 64537aa877a2ad08585d4cd9bf0d40e0 358 Gene3D G3DSA:1.10.1530.10 11 82 4.6E-20 T 06-07-2017 CAK95_RS10655 64537aa877a2ad08585d4cd9bf0d40e0 358 SUPERFAMILY SSF89733 11 352 4.05E-103 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS10655 64537aa877a2ad08585d4cd9bf0d40e0 358 Gene3D G3DSA:3.30.1370.60 83 281 1.3E-73 T 06-07-2017 CAK95_RS20835 00616fb45ac455255b3043716c81ee89 142 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 37 111 5.2E-36 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK95_RS20835 00616fb45ac455255b3043716c81ee89 142 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 11 115 32.485 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK95_RS20835 00616fb45ac455255b3043716c81ee89 142 SUPERFAMILY SSF141734 11 119 1.44E-46 T 06-07-2017 CAK95_RS20835 00616fb45ac455255b3043716c81ee89 142 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 60 114 4.0E-21 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 SUPERFAMILY SSF53850 94 297 7.6E-42 T 06-07-2017 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 Gene3D G3DSA:1.10.10.10 13 86 2.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 Pfam PF03466 LysR substrate binding domain 92 296 1.9E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 Gene3D G3DSA:3.40.190.10 96 180 1.0E-23 T 06-07-2017 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 Gene3D G3DSA:3.40.190.10 181 265 3.9E-22 T 06-07-2017 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 67 1.6E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12920 ac17bd6c8857a37ca38b2f6685165674 304 SUPERFAMILY SSF46785 13 89 4.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04615 787443991eab9e8a17060a4e65b4b5e9 141 Pfam PF06170 Protein of unknown function (DUF983) 34 118 3.2E-36 T 06-07-2017 IPR009325 Protein of unknown function DUF983 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 200 449 1.8E-16 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 Gene3D G3DSA:2.102.10.10 51 156 6.5E-22 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 SUPERFAMILY SSF50022 18 166 1.96E-46 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 94 117 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 SUPERFAMILY SSF55961 168 453 3.22E-40 T 06-07-2017 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 193 215 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 87 107 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 66 81 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 108 128 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 152 178 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 36 61 8.8E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 Gene3D G3DSA:3.90.380.10 157 455 4.0E-56 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS12550 25ce0584f4ecbd6b1732e49dde1ab080 463 Pfam PF00355 Rieske [2Fe-2S] domain 51 132 1.8E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 Pfam PF13145 PPIC-type PPIASE domain 247 365 1.1E-22 T 06-07-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 SUPERFAMILY SSF109998 241 296 5.1E-21 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 SUPERFAMILY SSF109998 40 167 5.1E-21 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 Pfam PF13624 SurA N-terminal domain 10 163 2.1E-36 T 06-07-2017 CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 SUPERFAMILY SSF54534 222 351 1.65E-13 T 06-07-2017 CAK95_RS23110 ddddeee79c618ee3c20e755dd0dc5c2e 631 Gene3D G3DSA:3.10.50.40 261 377 2.5E-18 T 06-07-2017 CAK95_RS02085 f2f0f810c810f7ccb237f7b8394cf672 208 Pfam PF01614 Bacterial transcriptional regulator 75 172 3.7E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS02085 f2f0f810c810f7ccb237f7b8394cf672 208 SUPERFAMILY SSF55781 23 198 1.77E-27 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS02085 f2f0f810c810f7ccb237f7b8394cf672 208 Gene3D G3DSA:3.30.450.40 25 201 2.4E-30 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS27500 73e76c1bdb49b1b18251db380405f031 547 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 102 547 2.9E-121 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAK95_RS27500 73e76c1bdb49b1b18251db380405f031 547 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 102 547 1.9E-134 T 06-07-2017 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 CAK95_RS27500 73e76c1bdb49b1b18251db380405f031 547 Pfam PF13727 CoA-binding domain 153 321 1.2E-14 T 06-07-2017 CAK95_RS27500 73e76c1bdb49b1b18251db380405f031 547 Pfam PF02397 Bacterial sugar transferase 357 538 1.3E-57 T 06-07-2017 IPR003362 Bacterial sugar transferase CAK95_RS19860 710b9bd1d010d179a501f1fd6e810d5f 362 SUPERFAMILY SSF53850 140 267 7.77E-6 T 06-07-2017 CAK95_RS19860 710b9bd1d010d179a501f1fd6e810d5f 362 PIRSF PIRSF039026 1 356 5.9E-122 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAK95_RS19860 710b9bd1d010d179a501f1fd6e810d5f 362 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 321 1.9E-62 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS27185 0b8932385b8f5bbb573efdeb3abc9488 418 Pfam PF00925 GTP cyclohydrolase II 236 373 2.9E-14 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK95_RS27185 0b8932385b8f5bbb573efdeb3abc9488 418 Pfam PF12471 GTP cyclohydrolase N terminal 8 196 1.0E-78 T 06-07-2017 IPR022163 GTP cyclohydrolase N-terminal CAK95_RS27185 0b8932385b8f5bbb573efdeb3abc9488 418 SUPERFAMILY SSF142695 202 375 1.44E-31 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK95_RS08085 0ed03131f3e7807db2dc4196e03e81ca 141 PIRSF PIRSF004638 1 141 6.1E-60 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAK95_RS08085 0ed03131f3e7807db2dc4196e03e81ca 141 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 3 141 6.6E-52 T 06-07-2017 IPR014351 Conserved hypothetical protein CHP00701 CAK95_RS08085 0ed03131f3e7807db2dc4196e03e81ca 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 2.0E-59 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 Gene3D G3DSA:1.20.1560.10 9 332 5.8E-42 T 06-07-2017 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 TIGRFAM TIGR01192 chvA: glucan exporter ATP-binding protein 1 584 1.3E-177 T 06-07-2017 IPR005896 Glucan exporter ATP-binding protein, NdvA GO:0005886|GO:0015441|GO:0015775 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 Pfam PF00664 ABC transporter transmembrane region 24 296 7.3E-33 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 SUPERFAMILY SSF52540 335 580 3.26E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 Gene3D G3DSA:3.40.50.300 344 573 1.2E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 SMART SM00382 369 555 2.1E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 SUPERFAMILY SSF90123 9 308 1.57E-45 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS04715 5191a5dc0d7df65d4a4cdd3935606704 595 Pfam PF00005 ABC transporter 362 509 2.3E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 Gene3D G3DSA:1.25.40.10 43 227 2.6E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 SMART SM00671 119 157 30.0 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 SMART SM00671 195 230 30.0 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 SMART SM00671 71 106 2.5E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 SMART SM00671 159 194 5.6E-7 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 SUPERFAMILY SSF81901 44 227 8.02E-31 T 06-07-2017 CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 Pfam PF08238 Sel1 repeat 71 103 3.9E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 Pfam PF08238 Sel1 repeat 159 193 1.1E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 Pfam PF08238 Sel1 repeat 124 154 0.093 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS24020 b980b5ca445e8e85cfa8326222800eba 267 Pfam PF08238 Sel1 repeat 195 225 0.3 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS11910 eaee23b79004691d2b35f6ff375c9f21 283 PIRSF PIRSF035875 1 283 4.6E-58 T 06-07-2017 IPR017039 Virulence factor BrkB CAK95_RS11910 eaee23b79004691d2b35f6ff375c9f21 283 Pfam PF03631 Virulence factor BrkB 17 270 1.2E-44 T 06-07-2017 IPR017039 Virulence factor BrkB CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 SUPERFAMILY SSF51735 6 255 1.1E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 Gene3D G3DSA:3.40.50.720 2 255 3.0E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28360 7e3af03e7a16567e18e072786d8a6a2f 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 255 1.2E-42 T 06-07-2017 CAK95_RS18440 912e5fb127a45bb9208898261a8f7dc3 391 Pfam PF13458 Periplasmic binding protein 25 360 1.4E-69 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS18440 912e5fb127a45bb9208898261a8f7dc3 391 SUPERFAMILY SSF53822 26 390 1.33E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS18440 912e5fb127a45bb9208898261a8f7dc3 391 Gene3D G3DSA:3.40.50.2300 297 349 1.9E-39 T 06-07-2017 CAK95_RS18440 912e5fb127a45bb9208898261a8f7dc3 391 Gene3D G3DSA:3.40.50.2300 21 148 1.9E-39 T 06-07-2017 CAK95_RS18440 912e5fb127a45bb9208898261a8f7dc3 391 Gene3D G3DSA:3.40.50.2300 149 296 4.8E-24 T 06-07-2017 CAK95_RS25235 063cbdf186a7aea0c388f75bc0d53eb7 247 Pfam PF13462 Thioredoxin 76 238 4.2E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25235 063cbdf186a7aea0c388f75bc0d53eb7 247 Gene3D G3DSA:3.40.30.10 69 240 2.6E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25235 063cbdf186a7aea0c388f75bc0d53eb7 247 SUPERFAMILY SSF52833 66 238 8.03E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS17780 cd03feb64768a81485965bc358088790 383 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 28 379 1.4E-106 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAK95_RS17780 cd03feb64768a81485965bc358088790 383 Gene3D G3DSA:3.40.640.10 26 260 2.3E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS17780 cd03feb64768a81485965bc358088790 383 Gene3D G3DSA:3.90.1150.10 265 382 1.8E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS17780 cd03feb64768a81485965bc358088790 383 SUPERFAMILY SSF53383 28 382 7.12E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS17780 cd03feb64768a81485965bc358088790 383 PIRSF PIRSF000390 6 383 2.4E-94 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 Pfam PF00656 Caspase domain 82 304 6.6E-37 T 06-07-2017 CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 SMART SM00115 73 306 0.0032 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 SUPERFAMILY SSF52129 71 306 1.33E-54 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 Gene3D G3DSA:3.40.50.1460 79 305 2.7E-22 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 PRINTS PR00376 Interleukin-1B converting enzyme signature 296 305 8.6E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 PRINTS PR00376 Interleukin-1B converting enzyme signature 194 212 8.6E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 PRINTS PR00376 Interleukin-1B converting enzyme signature 116 134 8.6E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS19810 5195fbcc9947ff757596e753c6a5621c 665 PRINTS PR00376 Interleukin-1B converting enzyme signature 80 93 8.6E-5 T 06-07-2017 IPR015917 Peptidase C14A, caspase catalytic domain GO:0006915|GO:0008234 CAK95_RS13660 fe14cf84dfc1203dbcf54ed6c96c76de 159 Gene3D G3DSA:3.40.1260.10 44 150 2.5E-17 T 06-07-2017 IPR027396 DsrEFH-like CAK95_RS13660 fe14cf84dfc1203dbcf54ed6c96c76de 159 SUPERFAMILY SSF75169 46 157 5.55E-17 T 06-07-2017 IPR027396 DsrEFH-like CAK95_RS13660 fe14cf84dfc1203dbcf54ed6c96c76de 159 Pfam PF02635 DsrE/DsrF-like family 47 140 1.8E-10 T 06-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein CAK95_RS09755 531660d650ca818b178bc09239a10d88 402 Pfam PF00266 Aminotransferase class-V 13 321 1.8E-32 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK95_RS09755 531660d650ca818b178bc09239a10d88 402 Gene3D G3DSA:3.90.1150.10 268 375 1.4E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS09755 531660d650ca818b178bc09239a10d88 402 Gene3D G3DSA:3.40.640.10 23 267 4.5E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS09755 531660d650ca818b178bc09239a10d88 402 SUPERFAMILY SSF53383 10 374 7.5E-104 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS09755 531660d650ca818b178bc09239a10d88 402 PIRSF PIRSF000524 6 395 2.4E-128 T 06-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 2.8E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 Gene3D G3DSA:3.40.190.10 97 182 3.0E-18 T 06-07-2017 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 Gene3D G3DSA:3.40.190.10 183 270 1.0E-17 T 06-07-2017 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 SUPERFAMILY SSF46785 12 118 1.45E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 SUPERFAMILY SSF53850 97 304 4.92E-38 T 06-07-2017 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 Pfam PF03466 LysR substrate binding domain 95 301 1.5E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS02725 81fe9975dfed8b0c9fca13f224e8295a 307 Gene3D G3DSA:1.10.10.10 12 92 7.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 Hamap MF_00300 Chorismate synthase [aroC]. 10 362 35.995 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 PIRSF PIRSF001456 3 366 3.5E-133 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 Pfam PF01264 Chorismate synthase 10 355 2.2E-131 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 ProSitePatterns PS00789 Chorismate synthase signature 3. 329 345 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 SUPERFAMILY SSF103263 4 360 8.63E-139 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 TIGRFAM TIGR00033 aroC: chorismate synthase 10 359 8.5E-126 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 ProSitePatterns PS00788 Chorismate synthase signature 2. 130 146 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS15890 5269478ae226484708c6f20872b7992c 374 Gene3D G3DSA:3.60.150.10 9 360 1.3E-149 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK95_RS26065 5ddc02f33df13e736b70189dbc7a6fcf 324 PIRSF PIRSF017082 1 291 4.7E-62 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26065 5ddc02f33df13e736b70189dbc7a6fcf 324 SUPERFAMILY SSF53850 116 279 1.63E-11 T 06-07-2017 CAK95_RS26065 5ddc02f33df13e736b70189dbc7a6fcf 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 292 2.3E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 Pfam PF01569 PAP2 superfamily 372 474 2.1E-12 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 Gene3D G3DSA:1.20.144.10 191 255 4.9E-13 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 SUPERFAMILY SSF48317 191 253 5.23E-12 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 Gene3D G3DSA:1.10.606.10 279 481 1.5E-43 T 06-07-2017 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 Gene3D G3DSA:1.10.606.10 83 162 5.8E-5 T 06-07-2017 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 CAK95_RS00015 0e5e1fb0f97b26ffcdf06513aa1ee7c9 487 SUPERFAMILY SSF48317 279 481 4.06E-44 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK95_RS16515 eb7066c3c97420e6c8abf228fecb6daa 447 PIRSF PIRSF006060 2 447 2.9E-62 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS16515 eb7066c3c97420e6c8abf228fecb6daa 447 Pfam PF13520 Amino acid permease 16 418 1.1E-45 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 Gene3D G3DSA:3.40.720.10 116 480 5.9E-121 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 Gene3D G3DSA:3.40.720.10 520 583 5.9E-121 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 SUPERFAMILY SSF53649 114 439 3.66E-117 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 SUPERFAMILY SSF53649 474 579 3.66E-117 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 Pfam PF00245 Alkaline phosphatase 121 435 4.1E-70 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 Pfam PF00245 Alkaline phosphatase 540 578 9.8E-6 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 SMART SM00098 122 579 9.1E-47 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 PRINTS PR00113 Alkaline phosphatase signature 221 241 6.6E-37 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 PRINTS PR00113 Alkaline phosphatase signature 121 141 6.6E-37 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 PRINTS PR00113 Alkaline phosphatase signature 265 275 6.6E-37 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 PRINTS PR00113 Alkaline phosphatase signature 352 381 6.6E-37 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS07945 669f97697a4af5a1f90a6a8f5bfbf81d 589 PRINTS PR00113 Alkaline phosphatase signature 176 191 6.6E-37 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 SUPERFAMILY SSF54292 5 81 6.16E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 Pfam PF01799 [2Fe-2S] binding domain 76 147 9.0E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 Gene3D G3DSA:1.10.150.120 78 153 1.2E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 Gene3D G3DSA:3.10.20.30 4 77 1.3E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 62 6.5E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS14275 9a3fa432d16d95b8f3c2ba59d667985e 160 SUPERFAMILY SSF47741 76 154 2.22E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS18740 f8b4567373f50f1429acd398dcf66299 160 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 90 101 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18740 f8b4567373f50f1429acd398dcf66299 160 SUPERFAMILY SSF55083 1 157 1.7E-48 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18740 f8b4567373f50f1429acd398dcf66299 160 Gene3D G3DSA:3.30.70.560 3 153 2.7E-51 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18740 f8b4567373f50f1429acd398dcf66299 160 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 135 1.1E-39 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18740 f8b4567373f50f1429acd398dcf66299 160 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 135 2.9E-34 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 SMART SM00893 3 181 3.9E-55 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 Gene3D G3DSA:3.40.50.1220 183 309 6.7E-59 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 Gene3D G3DSA:3.40.50.620 1 181 8.8E-62 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 272 1.3E-34 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 SUPERFAMILY SSF52402 3 183 2.79E-58 T 06-07-2017 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 PIRSF PIRSF000089 1 314 4.4E-106 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 Pfam PF01012 Electron transfer flavoprotein domain 4 170 2.4E-41 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK95_RS11945 a192c142859967f9f7e6b7d3a4c3afd6 314 SUPERFAMILY SSF52467 188 307 4.73E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 345 414 7.1E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 199 332 1.7E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SUPERFAMILY SSF47384 330 415 4.71E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SMART SM00388 345 414 3.5E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Gene3D G3DSA:1.10.287.130 352 400 4.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Gene3D G3DSA:3.30.565.10 401 570 1.2E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Gene3D G3DSA:3.30.450.20 201 351 3.9E-27 T 06-07-2017 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Pfam PF00989 PAS fold 202 306 3.3E-8 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SUPERFAMILY SSF55785 197 323 1.18E-15 T 06-07-2017 IPR000014 PAS domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SMART SM00091 202 268 3.6E-10 T 06-07-2017 IPR000014 PAS domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 525 2.2E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 511 2.2E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 550 2.2E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 569 2.2E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 461 571 1.6E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SMART SM00387 460 572 2.5E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS18850 d21e7f1ba0a86ffb36a9fe8006046208 603 SUPERFAMILY SSF55874 403 570 2.23E-46 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.7E-6 T 06-07-2017 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 296 1.7E-6 T 06-07-2017 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 Gene3D G3DSA:3.50.50.60 356 414 2.4E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 Gene3D G3DSA:3.50.50.60 110 132 2.4E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 Gene3D G3DSA:3.50.50.60 187 267 2.4E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 Gene3D G3DSA:3.50.50.60 3 60 2.4E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 SUPERFAMILY SSF54373 270 356 1.39E-9 T 06-07-2017 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 Pfam PF01266 FAD dependent oxidoreductase 5 395 2.3E-56 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 SUPERFAMILY SSF51905 106 268 6.47E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 SUPERFAMILY SSF51905 4 58 6.47E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20235 c69bf2d368ceb7013beb1bd104b30875 415 SUPERFAMILY SSF51905 356 414 6.47E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 Gene3D G3DSA:3.10.20.30 4 77 7.6E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 SUPERFAMILY SSF47741 87 153 9.29E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 65 1.2E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 Pfam PF01799 [2Fe-2S] binding domain 76 149 3.8E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 SUPERFAMILY SSF54292 5 90 4.59E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS18025 3732a7d101e934d3739c1535cb032beb 155 Gene3D G3DSA:1.10.150.120 78 153 2.3E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS18375 9f2b1d64ad4fad25f44f63d436e156e4 132 SUPERFAMILY SSF101447 30 41 7.85E-5 T 06-07-2017 CAK95_RS20390 af2d50ef7a5092cc8b051e91f9ba78a4 168 ProSitePatterns PS00934 Glyoxalase I signature 1. 17 38 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAK95_RS20390 af2d50ef7a5092cc8b051e91f9ba78a4 168 SUPERFAMILY SSF54593 13 165 2.15E-48 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20390 af2d50ef7a5092cc8b051e91f9ba78a4 168 Gene3D G3DSA:3.10.180.10 9 141 2.5E-37 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20390 af2d50ef7a5092cc8b051e91f9ba78a4 168 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 129 1.6E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS15910 6c4252a1ca6ed9c3ce7460dc9cc34464 472 Pfam PF01554 MatE 33 192 3.6E-30 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS15910 6c4252a1ca6ed9c3ce7460dc9cc34464 472 Pfam PF01554 MatE 259 424 6.2E-25 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS15910 6c4252a1ca6ed9c3ce7460dc9cc34464 472 TIGRFAM TIGR00797 matE: MATE efflux family protein 33 438 6.0E-70 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS15910 6c4252a1ca6ed9c3ce7460dc9cc34464 472 PIRSF PIRSF006603 24 467 2.7E-50 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS19175 6e5328398095b10810aa88970f3318b6 167 Pfam PF03918 Cytochrome C biogenesis protein 12 159 1.3E-51 T 06-07-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family CAK95_RS15150 b55c7b03eabaca16ad23125b2051b2f6 121 SUPERFAMILY SSF52172 1 117 7.68E-37 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS15150 b55c7b03eabaca16ad23125b2051b2f6 121 Gene3D G3DSA:3.40.50.2300 2 118 1.7E-36 T 06-07-2017 CAK95_RS15150 b55c7b03eabaca16ad23125b2051b2f6 121 SMART SM00448 2 115 1.7E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15150 b55c7b03eabaca16ad23125b2051b2f6 121 Pfam PF00072 Response regulator receiver domain 5 111 2.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06390 8e4ec7b3c24549f53abf7fd40c0af1f2 607 Pfam PF07287 Protein of unknown function (DUF1446) 8 345 4.4E-120 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 SUPERFAMILY SSF46626 57 163 8.86E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 SUPERFAMILY SSF46626 275 361 5.15E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 75 155 4.8E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 Gene3D G3DSA:1.10.760.10 63 161 2.1E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 SUPERFAMILY SSF46626 195 263 2.53E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 Gene3D G3DSA:1.10.760.10 187 263 3.2E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS11625 b9ef52eaa94f31f9d471290322d99623 379 Gene3D G3DSA:1.10.760.10 285 362 7.8E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS05480 1f37eb3fe733d3e93b8a0e0c10c980ae 326 Pfam PF01040 UbiA prenyltransferase family 48 293 2.3E-59 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK95_RS05480 1f37eb3fe733d3e93b8a0e0c10c980ae 326 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 86 108 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site CAK95_RS05480 1f37eb3fe733d3e93b8a0e0c10c980ae 326 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 32 316 19.947 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK95_RS05480 1f37eb3fe733d3e93b8a0e0c10c980ae 326 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 34 314 3.7E-99 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 Gene3D G3DSA:1.10.287.130 182 259 2.9E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 SMART SM00387 287 396 4.0E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 SUPERFAMILY SSF55874 252 394 2.62E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 SMART SM00304 137 189 0.0015 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 349 6.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 6.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 6.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 Gene3D G3DSA:3.30.565.10 260 396 2.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 SUPERFAMILY SSF47384 174 248 1.0E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 Pfam PF00512 His Kinase A (phospho-acceptor) domain 190 266 1.6E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 Pfam PF00672 HAMP domain 119 185 3.3E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 SMART SM00388 190 248 2.9E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS05025 f43f7769a4564b19d93640589c2a8ff3 398 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 385 5.1E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS17610 642a4e8349b84e6d0f47894bce7a0876 280 Gene3D G3DSA:3.40.50.150 57 199 8.4E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17610 642a4e8349b84e6d0f47894bce7a0876 280 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 62 193 9.2E-14 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS17610 642a4e8349b84e6d0f47894bce7a0876 280 SUPERFAMILY SSF53335 51 224 4.48E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS17610 642a4e8349b84e6d0f47894bce7a0876 280 Pfam PF05050 Methyltransferase FkbM domain 64 203 2.5E-15 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS24990 cbe329462b7ca0f108b6d3bb3478caf1 438 SUPERFAMILY SSF101960 33 434 5.62E-102 T 06-07-2017 CAK95_RS24990 cbe329462b7ca0f108b6d3bb3478caf1 438 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 426 8.7E-82 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CAK95_RS24990 cbe329462b7ca0f108b6d3bb3478caf1 438 Pfam PF01458 Uncharacterized protein family (UPF0051) 185 409 1.4E-70 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAK95_RS13465 ed45e0417a66060630f41ad608acb879 403 SUPERFAMILY SSF103473 10 393 3.92E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS13465 ed45e0417a66060630f41ad608acb879 403 Gene3D G3DSA:1.20.1250.20 30 193 2.6E-20 T 06-07-2017 CAK95_RS13465 ed45e0417a66060630f41ad608acb879 403 Gene3D G3DSA:1.20.1250.20 213 394 5.5E-19 T 06-07-2017 CAK95_RS13465 ed45e0417a66060630f41ad608acb879 403 Pfam PF07690 Major Facilitator Superfamily 223 392 4.4E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS13465 ed45e0417a66060630f41ad608acb879 403 Pfam PF07690 Major Facilitator Superfamily 32 204 2.6E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS00325 89f5bef59bbe8ce9395d86b03fab868a 326 Gene3D G3DSA:3.20.20.140 4 324 2.0E-83 T 06-07-2017 CAK95_RS00325 89f5bef59bbe8ce9395d86b03fab868a 326 SUPERFAMILY SSF51556 7 324 7.71E-82 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00325 89f5bef59bbe8ce9395d86b03fab868a 326 Pfam PF04909 Amidohydrolase 39 324 9.3E-46 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS25045 f9d7c2d1228c34facfdc4dc50f7c4c66 156 Pfam PF00578 AhpC/TSA family 8 135 9.5E-33 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS25045 f9d7c2d1228c34facfdc4dc50f7c4c66 156 PIRSF PIRSF000239 2 156 1.8E-17 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS25045 f9d7c2d1228c34facfdc4dc50f7c4c66 156 SUPERFAMILY SSF52833 7 156 5.81E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS25045 f9d7c2d1228c34facfdc4dc50f7c4c66 156 Gene3D G3DSA:3.40.30.10 7 156 1.5E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01645 083b01c62d59577d8cb623ee79b59478 158 Gene3D G3DSA:3.90.1170.40 3 149 6.7E-51 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS01645 083b01c62d59577d8cb623ee79b59478 158 SUPERFAMILY SSF54690 4 149 7.59E-49 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS01645 083b01c62d59577d8cb623ee79b59478 158 Pfam PF02391 MoaE protein 10 120 8.2E-34 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 SUPERFAMILY SSF50494 58 296 6.43E-62 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Gene3D G3DSA:2.40.10.10 60 195 2.6E-35 T 06-07-2017 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 142 154 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 163 183 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 236 253 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 344 356 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 258 275 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 PRINTS PR00834 HtrA/DegQ protease family signature 202 226 3.0E-55 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 SUPERFAMILY SSF50156 303 399 4.07E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Pfam PF13365 Trypsin-like peptidase domain 133 265 3.2E-33 T 06-07-2017 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 61 504 1.3E-137 T 06-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Pfam PF13180 PDZ domain 421 494 3.6E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Pfam PF13180 PDZ domain 304 395 1.4E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 SMART SM00228 304 386 4.2E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 SMART SM00228 419 498 2.6E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 SUPERFAMILY SSF50156 436 506 5.92E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Gene3D G3DSA:2.30.42.10 306 401 3.7E-30 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Gene3D G3DSA:2.40.10.10 198 305 7.0E-40 T 06-07-2017 CAK95_RS19180 9fc5087dc33f96bc6cf5455333594a62 510 Gene3D G3DSA:2.30.42.10 435 505 1.8E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK95_RS14325 457c879605dfdb0e5dfb787ee9a045ca 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 5.9E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 7.4E-16 T 06-07-2017 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 7.4E-16 T 06-07-2017 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 7.4E-16 T 06-07-2017 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 7.4E-16 T 06-07-2017 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.4E-16 T 06-07-2017 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 Pfam PF01494 FAD binding domain 6 351 1.2E-23 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 SUPERFAMILY SSF51905 7 178 4.29E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 SUPERFAMILY SSF51905 278 379 4.29E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 Gene3D G3DSA:3.50.50.60 278 362 3.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 Gene3D G3DSA:3.50.50.60 6 183 3.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS20685 9d246e8806546e67f015a03c4455ac92 397 SUPERFAMILY SSF54373 186 283 4.9E-16 T 06-07-2017 CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 49 6.9E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 17 31 4.8E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 47 4.8E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 SMART SM00345 3 57 8.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 Gene3D G3DSA:1.10.10.10 2 58 4.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 SUPERFAMILY SSF46785 2 85 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 SMART SM00895 67 204 4.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 SUPERFAMILY SSF48008 64 209 1.65E-15 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 Gene3D G3DSA:1.20.120.530 61 216 2.2E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS26160 51b24e1a1944ab88dff87100b18d3668 236 Pfam PF07729 FCD domain 69 202 4.3E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS12340 8a88f689813bcd7a67e831d8e6760154 126 Gene3D G3DSA:2.60.120.10 38 122 2.8E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS12340 8a88f689813bcd7a67e831d8e6760154 126 SUPERFAMILY SSF51182 24 124 3.51E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 Gene3D G3DSA:2.40.240.10 6 96 5.0E-31 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 186 1.6E-28 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 Gene3D G3DSA:2.170.120.20 102 192 3.5E-29 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 184 2.9E-43 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 SUPERFAMILY SSF50715 5 192 1.24E-57 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 Pfam PF01386 Ribosomal L25p family 7 94 8.4E-24 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 187 29.135 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK95_RS13495 3fd4a8f80375f3b48c47d52d1d1aba07 226 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 97 3.0E-27 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 SUPERFAMILY SSF52402 8 210 1.7E-64 T 06-07-2017 CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 Gene3D G3DSA:3.40.50.620 244 253 3.0E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 Gene3D G3DSA:3.40.50.620 6 210 3.0E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 30 256 1.0E-56 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 2.1E-142 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK95_RS26665 fc14849779c5e65558d4c6fd3b5e1389 302 PIRSF PIRSF002936 1 302 4.2E-138 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK95_RS00755 5e882464bf1d27656a7d775741a76a82 300 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 14 291 2.9E-39 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CAK95_RS00755 5e882464bf1d27656a7d775741a76a82 300 SUPERFAMILY SSF53067 11 120 3.7E-24 T 06-07-2017 CAK95_RS00755 5e882464bf1d27656a7d775741a76a82 300 Gene3D G3DSA:3.30.420.40 208 277 7.2E-6 T 06-07-2017 CAK95_RS00755 5e882464bf1d27656a7d775741a76a82 300 SUPERFAMILY SSF53067 123 291 4.54E-43 T 06-07-2017 CAK95_RS24830 fbf18d6892c41313ea1cfd7535a6b56d 319 Gene3D G3DSA:3.60.15.10 30 316 3.9E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24830 fbf18d6892c41313ea1cfd7535a6b56d 319 Pfam PF00753 Metallo-beta-lactamase superfamily 93 252 5.6E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24830 fbf18d6892c41313ea1cfd7535a6b56d 319 SMART SM00849 89 304 4.5E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS24830 fbf18d6892c41313ea1cfd7535a6b56d 319 SUPERFAMILY SSF56281 34 317 5.9E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04510 090e1f8aafadea11cdf8aab09f317b52 310 Pfam PF02401 LytB protein 5 281 8.3E-92 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS04510 090e1f8aafadea11cdf8aab09f317b52 310 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 4 283 1.0E-99 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS04510 090e1f8aafadea11cdf8aab09f317b52 310 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 3 285 38.193 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 SUPERFAMILY SSF46785 5 86 1.27E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 Gene3D G3DSA:3.40.190.10 182 269 3.8E-11 T 06-07-2017 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.7E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 SUPERFAMILY SSF53850 98 301 1.45E-30 T 06-07-2017 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 Pfam PF03466 LysR substrate binding domain 98 300 1.9E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 Gene3D G3DSA:3.40.190.10 98 181 5.7E-14 T 06-07-2017 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 TIGRFAM TIGR02424 TF_pcaQ: pca operon transcription factor PcaQ 5 301 3.2E-106 T 06-07-2017 IPR012787 Pca transcription factor PcaQ GO:0003677|GO:0019619|GO:0045893 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS05300 fc804e5595af2a3790e9f50aeffb8aa5 303 Gene3D G3DSA:1.10.10.10 6 88 9.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 SUPERFAMILY SSF63411 2 206 2.75E-60 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 Pfam PF05193 Peptidase M16 inactive domain 166 338 6.8E-41 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 Gene3D G3DSA:3.30.830.10 12 220 7.6E-63 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 SUPERFAMILY SSF63411 224 404 3.83E-48 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 34 57 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 Pfam PF00675 Insulinase (Peptidase family M16) 14 160 3.0E-44 T 06-07-2017 IPR011765 Peptidase M16, N-terminal CAK95_RS05515 f2cd197f57d1e9c7616a57b84beb3291 423 Gene3D G3DSA:3.30.830.10 221 418 7.8E-62 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 57 272 7.1E-54 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 Pfam PF05036 Sporulation related domain 489 567 2.4E-9 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 133 150 5.3E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 80 91 5.3E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 160 173 5.3E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 Gene3D G3DSA:3.30.70.1070 486 567 1.1E-4 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 Gene3D G3DSA:3.40.710.10 58 287 6.7E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 SUPERFAMILY SSF110997 489 566 4.18E-5 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS21935 c23dced30be4c23772d329011ea78d46 568 SUPERFAMILY SSF56601 22 287 2.94E-68 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 251 7.1E-28 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 Gene3D G3DSA:3.60.10.10 1 259 8.9E-84 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 SUPERFAMILY SSF56219 1 259 3.53E-85 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 215 226 - T 06-07-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 259 2.9E-72 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 06-07-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CAK95_RS23980 34ea43694be4666f982d41ba19af62c0 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 257 2.7E-74 T 06-07-2017 CAK95_RS08850 2d8639145f3022432c2641cf130ee64f 126 Gene3D G3DSA:3.40.1350.10 21 125 6.0E-34 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAK95_RS08850 2d8639145f3022432c2641cf130ee64f 126 SUPERFAMILY SSF52980 21 119 1.43E-24 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS08850 2d8639145f3022432c2641cf130ee64f 126 Pfam PF02021 Uncharacterised protein family UPF0102 21 110 4.8E-24 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAK95_RS08850 2d8639145f3022432c2641cf130ee64f 126 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 123 20.689 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAK95_RS13030 0aef76cb84ab38bef34c5e58893d0d5b 281 SUPERFAMILY SSF52540 18 257 2.43E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13030 0aef76cb84ab38bef34c5e58893d0d5b 281 SMART SM00382 44 238 1.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13030 0aef76cb84ab38bef34c5e58893d0d5b 281 Gene3D G3DSA:3.40.50.300 15 255 2.9E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13030 0aef76cb84ab38bef34c5e58893d0d5b 281 Pfam PF00005 ABC transporter 35 186 3.5E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 34 427 5.3E-161 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 Gene3D G3DSA:3.40.50.1980 28 240 6.9E-80 T 06-07-2017 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 SUPERFAMILY SSF53720 28 429 2.35E-86 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 428 42.385 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 171 197 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 201 226 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 362 380 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 321 346 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 34 58 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 4.1E-84 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 PIRSF PIRSF000099 6 431 1.9E-161 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS11305 22f542806650a5fef9553740ba02ecb6 431 Pfam PF00815 Histidinol dehydrogenase 24 428 3.2E-168 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK95_RS24745 335565f0fbcbc912d273ddea18f8d623 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 253 4.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24745 335565f0fbcbc912d273ddea18f8d623 264 Gene3D G3DSA:1.10.3720.10 64 255 5.2E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS24745 335565f0fbcbc912d273ddea18f8d623 264 SUPERFAMILY SSF161098 65 247 6.15E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23505 373ec8d3efd779066ea33a252d31edc0 326 Pfam PF06629 MltA-interacting protein MipA 108 326 2.5E-45 T 06-07-2017 IPR010583 MltA-interacting MipA CAK95_RS23505 373ec8d3efd779066ea33a252d31edc0 326 Gene3D G3DSA:2.40.160.10 148 298 4.1E-4 T 06-07-2017 IPR023614 Porin domain CAK95_RS23505 373ec8d3efd779066ea33a252d31edc0 326 SUPERFAMILY SSF56935 135 303 3.66E-8 T 06-07-2017 CAK95_RS26845 f3622644a52f2935e07ef009029875f2 353 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 6 338 5.2E-146 T 06-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAK95_RS26845 f3622644a52f2935e07ef009029875f2 353 SUPERFAMILY SSF51735 1 336 1.39E-90 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26845 f3622644a52f2935e07ef009029875f2 353 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 325 1.1E-95 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26845 f3622644a52f2935e07ef009029875f2 353 Gene3D G3DSA:3.90.25.10 195 337 8.4E-52 T 06-07-2017 CAK95_RS26845 f3622644a52f2935e07ef009029875f2 353 Gene3D G3DSA:3.40.50.720 2 194 2.4E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10105 7e4995be086d3e923c9806121539d8a7 353 SUPERFAMILY SSF51556 29 353 8.81E-80 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS10105 7e4995be086d3e923c9806121539d8a7 353 Pfam PF04909 Amidohydrolase 29 353 3.5E-38 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS10105 7e4995be086d3e923c9806121539d8a7 353 Gene3D G3DSA:3.20.20.140 29 353 3.5E-85 T 06-07-2017 CAK95_RS26360 14b60dbb06e33b45974e199730fd0384 291 Pfam PF04909 Amidohydrolase 76 288 8.2E-52 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS26360 14b60dbb06e33b45974e199730fd0384 291 SUPERFAMILY SSF51556 10 288 8.75E-66 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS26360 14b60dbb06e33b45974e199730fd0384 291 Gene3D G3DSA:3.20.20.140 10 289 5.1E-65 T 06-07-2017 CAK95_RS13570 abc1f560816ddba4a69c29c4a38b12c2 158 Pfam PF02381 MraZ protein, putative antitoxin-like 83 133 4.2E-7 T 06-07-2017 IPR020603 MraZ domain CAK95_RS13570 abc1f560816ddba4a69c29c4a38b12c2 158 SUPERFAMILY SSF89447 3 139 3.45E-31 T 06-07-2017 CAK95_RS13570 abc1f560816ddba4a69c29c4a38b12c2 158 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 158 31.837 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAK95_RS13570 abc1f560816ddba4a69c29c4a38b12c2 158 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 10 122 1.0E-11 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 SMART SM01008 20 135 3.0E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 729 1.2E-176 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 179 286 5.0E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 289 363 1.0E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 124 178 1.0E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.90.1170.50 4 123 2.2E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 465 598 1.8E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 644 792 3.2E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Gene3D G3DSA:3.30.365.10 366 464 3.2E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 134 6.3E-29 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 SUPERFAMILY SSF56003 127 793 3.79E-185 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28600 a7eeda78637ed018e56bd7043d41b617 797 SUPERFAMILY SSF54665 5 156 9.16E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS21825 56c19f733def967415e658508627b2bc 535 Pfam PF01039 Carboxyl transferase domain 48 526 5.6E-150 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21825 56c19f733def967415e658508627b2bc 535 SUPERFAMILY SSF52096 278 535 4.68E-85 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21825 56c19f733def967415e658508627b2bc 535 Gene3D G3DSA:3.90.226.10 29 275 3.2E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21825 56c19f733def967415e658508627b2bc 535 Gene3D G3DSA:3.90.226.10 276 530 2.4E-91 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21825 56c19f733def967415e658508627b2bc 535 SUPERFAMILY SSF52096 23 268 4.98E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS20620 bbe15502fec08b4512d919d54cea5218 313 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 312 2.1E-95 T 06-07-2017 IPR007296 Domain of unknown function DUF403 CAK95_RS19280 bb69eaec6e9dc8b7d1970d98a5ff7acc 85 Gene3D G3DSA:3.40.50.1820 9 84 7.6E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS19280 bb69eaec6e9dc8b7d1970d98a5ff7acc 85 SUPERFAMILY SSF53474 14 84 1.71E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12135 f39539b5bda92e25a6070237758e6419 192 Pfam PF04752 ChaC-like protein 12 180 1.6E-47 T 06-07-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 CAK95_RS12135 f39539b5bda92e25a6070237758e6419 192 SUPERFAMILY SSF110857 12 142 3.79E-14 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK95_RS12135 f39539b5bda92e25a6070237758e6419 192 Gene3D G3DSA:3.10.490.10 9 176 7.4E-23 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 SUPERFAMILY SSF54197 6 139 2.94E-39 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 Gene3D G3DSA:3.30.428.10 7 139 1.9E-38 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 PRINTS PR00332 Histidine triad family signature 9 25 2.6E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 PRINTS PR00332 Histidine triad family signature 30 48 2.6E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 PRINTS PR00332 Histidine triad family signature 97 107 2.6E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS21990 f9a23710df2b05246264c0a3ffdbcbe1 142 Pfam PF01230 HIT domain 15 111 8.2E-28 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS01865 a4536e23c8c43cbf0eae086813f308d8 327 SUPERFAMILY SSF53850 28 259 3.96E-37 T 06-07-2017 CAK95_RS01865 a4536e23c8c43cbf0eae086813f308d8 327 Pfam PF09084 NMT1/THI5 like 118 256 5.2E-16 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS01865 a4536e23c8c43cbf0eae086813f308d8 327 Gene3D G3DSA:3.40.190.10 118 242 3.4E-23 T 06-07-2017 CAK95_RS14230 f35753404191139746166a508d8c15b7 184 Gene3D G3DSA:3.40.50.720 2 101 1.9E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14230 f35753404191139746166a508d8c15b7 184 SUPERFAMILY SSF51735 2 133 2.37E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 Gene3D G3DSA:3.40.50.300 2 212 2.8E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 SMART SM00490 259 340 1.4E-33 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 SMART SM00487 21 223 1.9E-60 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 Gene3D G3DSA:3.40.50.300 213 374 9.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 Pfam PF00271 Helicase conserved C-terminal domain 232 340 8.9E-29 T 06-07-2017 IPR001650 Helicase, C-terminal CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 SUPERFAMILY SSF52540 76 361 1.72E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20000 716fbb30d769488f4aebcca5c478795c 491 Pfam PF00270 DEAD/DEAH box helicase 26 196 6.3E-51 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 117 151 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 5 157 44.202 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 9.3E-31 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 9.3E-31 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 142 154 9.3E-31 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 9.3E-31 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 9.3E-31 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 7 154 2.2E-44 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 7 158 3.0E-43 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 Gene3D G3DSA:3.30.420.10 6 159 3.5E-57 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS04070 1468dc108c7157785bf412ce1052b11c 168 SUPERFAMILY SSF53098 6 158 3.22E-47 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS21140 a3d3f2e978c08a84b390a51790c3cbbc 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 212 1.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21140 a3d3f2e978c08a84b390a51790c3cbbc 216 Gene3D G3DSA:1.10.3720.10 11 212 8.8E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21140 a3d3f2e978c08a84b390a51790c3cbbc 216 SUPERFAMILY SSF161098 12 204 2.35E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21140 a3d3f2e978c08a84b390a51790c3cbbc 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 1.9E-27 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS22315 b1ef89ea37e18e6547b02d4a372ff94d 230 SMART SM00987 49 215 2.1E-28 T 06-07-2017 CAK95_RS22315 b1ef89ea37e18e6547b02d4a372ff94d 230 SMART SM00986 49 215 2.1E-28 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS22315 b1ef89ea37e18e6547b02d4a372ff94d 230 SUPERFAMILY SSF52141 23 224 9.81E-46 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS22315 b1ef89ea37e18e6547b02d4a372ff94d 230 Pfam PF03167 Uracil DNA glycosylase superfamily 51 218 2.8E-27 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS22315 b1ef89ea37e18e6547b02d4a372ff94d 230 Gene3D G3DSA:3.40.470.10 21 220 5.7E-52 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK95_RS02515 35ba94b675240a0318d69b2996064f1d 154 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 35 142 6.3E-25 T 06-07-2017 IPR018754 Protein of unknown function DUF2285 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 1.2E-37 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 1.2E-37 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 1.2E-37 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 1.2E-37 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 1.2E-37 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 36.338 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 283 1.4E-106 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 Gene3D G3DSA:3.90.226.10 19 282 3.1E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 Pfam PF01039 Carboxyl transferase domain 92 265 8.0E-17 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS10990 77e741be37810be06b38d98bd3fa5d45 301 SUPERFAMILY SSF52096 25 281 2.32E-82 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 Gene3D G3DSA:1.10.10.60 16 68 3.4E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 71 9.8E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 Gene3D G3DSA:1.10.357.10 69 202 1.3E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK95_RS15035 b1cd7a1766a671a3126101bd69f16a8d 213 SUPERFAMILY SSF46689 16 91 9.45E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS00635 57158899d659d968ef2600c3b4f36253 169 Gene3D G3DSA:3.40.630.30 6 136 8.2E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS00635 57158899d659d968ef2600c3b4f36253 169 Pfam PF13527 Acetyltransferase (GNAT) domain 12 127 1.4E-5 T 06-07-2017 CAK95_RS00635 57158899d659d968ef2600c3b4f36253 169 SUPERFAMILY SSF55729 6 135 7.03E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS16510 69c336962cfc688ce0f672893514d6fb 535 Gene3D G3DSA:3.50.50.60 241 321 6.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16510 69c336962cfc688ce0f672893514d6fb 535 Gene3D G3DSA:3.50.50.60 4 58 6.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16510 69c336962cfc688ce0f672893514d6fb 535 Gene3D G3DSA:3.50.50.60 147 179 6.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16510 69c336962cfc688ce0f672893514d6fb 535 Pfam PF01593 Flavin containing amine oxidoreductase 16 330 8.3E-13 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS16510 69c336962cfc688ce0f672893514d6fb 535 SUPERFAMILY SSF51905 4 412 2.2E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 Pfam PF09335 SNARE associated Golgi protein 547 663 1.3E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 Pfam PF13091 PLD-like domain 258 388 3.0E-15 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 SMART SM00155 130 157 0.36 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 SMART SM00155 347 374 1.6E-5 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 SUPERFAMILY SSF56024 252 388 1.3E-24 T 06-07-2017 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 Gene3D G3DSA:3.30.870.10 15 243 4.7E-24 T 06-07-2017 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 Gene3D G3DSA:3.30.870.10 255 391 2.1E-21 T 06-07-2017 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 Pfam PF00614 Phospholipase D Active site motif 133 156 1.1E-6 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAK95_RS21810 bb34e6c47cb78cefde83b42055d37db4 705 SUPERFAMILY SSF56024 7 242 9.42E-31 T 06-07-2017 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 SUPERFAMILY SSF54373 310 387 7.85E-9 T 06-07-2017 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 SUPERFAMILY SSF51905 376 439 2.05E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 SUPERFAMILY SSF51905 31 297 2.05E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 Pfam PF01593 Flavin containing amine oxidoreductase 41 437 1.7E-41 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 Gene3D G3DSA:3.50.50.60 28 112 2.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 Gene3D G3DSA:3.50.50.60 200 299 2.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 Gene3D G3DSA:3.50.50.60 396 440 2.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 405 420 1.0E-5 T 06-07-2017 CAK95_RS08985 45da87cb5570199e4ec1d01e3458e6b3 482 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 32 54 1.0E-5 T 06-07-2017 CAK95_RS07425 0f545d96a1918a64920638dde380d03b 186 SUPERFAMILY SSF88723 43 176 1.37E-11 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS07425 0f545d96a1918a64920638dde380d03b 186 Gene3D G3DSA:3.40.50.1010 43 176 2.1E-6 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS06660 67c1b21eb0aab177ffc34fd33ed9b700 248 TIGRFAM TIGR02522 pilus_cpaD: pilus (Caulobacter type) biogenesis lipoprotein CpaD 23 228 3.5E-54 T 06-07-2017 IPR013361 Pilus biogenesis CpaD CAK95_RS06660 67c1b21eb0aab177ffc34fd33ed9b700 248 Pfam PF09476 Pilus biogenesis CpaD protein (pilus_cpaD) 25 226 1.3E-63 T 06-07-2017 IPR019027 Pilus biogenesis CpaD-related CAK95_RS24955 6bb1d264791175d19e6bca48259c4560 355 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 176 339 1.2E-52 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS24955 6bb1d264791175d19e6bca48259c4560 355 SMART SM00267 163 340 8.9E-54 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS24955 6bb1d264791175d19e6bca48259c4560 355 Pfam PF00990 Diguanylate cyclase, GGDEF domain 178 336 6.4E-47 T 06-07-2017 IPR000160 GGDEF domain CAK95_RS24955 6bb1d264791175d19e6bca48259c4560 355 Gene3D G3DSA:3.30.70.270 179 339 4.7E-52 T 06-07-2017 CAK95_RS24955 6bb1d264791175d19e6bca48259c4560 355 SUPERFAMILY SSF55073 182 339 7.53E-45 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS02360 256bbf48489aba8bdbc3641970fa5f76 332 Pfam PF00437 Type II/IV secretion system protein 27 291 1.5E-83 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAK95_RS02360 256bbf48489aba8bdbc3641970fa5f76 332 SUPERFAMILY SSF52540 27 288 6.02E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02360 256bbf48489aba8bdbc3641970fa5f76 332 Gene3D G3DSA:3.30.450.90 26 118 7.9E-13 T 06-07-2017 CAK95_RS02360 256bbf48489aba8bdbc3641970fa5f76 332 Gene3D G3DSA:3.40.50.300 123 289 5.4E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02360 256bbf48489aba8bdbc3641970fa5f76 332 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 13 314 1.4E-132 T 06-07-2017 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 CAK95_RS00280 6ace7476e6b8e0186b8ff4c861bab47b 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 288 7.0E-29 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 97 1.6E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 Gene3D G3DSA:1.20.120.530 102 239 3.2E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 SMART SM00345 39 97 5.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 SUPERFAMILY SSF48008 103 235 1.31E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 SMART SM00895 107 229 3.6E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 Gene3D G3DSA:1.10.10.10 32 98 6.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 SUPERFAMILY SSF46785 32 101 1.92E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12325 664facf914141692921b8b9d179f19f8 263 Pfam PF07729 FCD domain 107 228 1.3E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 SUPERFAMILY SSF47090 383 453 1.36E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Gene3D G3DSA:1.10.530.10 172 187 4.8E-5 T 06-07-2017 CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Gene3D G3DSA:1.10.530.10 232 257 4.8E-5 T 06-07-2017 CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Gene3D G3DSA:1.10.530.10 128 171 9.7E-59 T 06-07-2017 CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Gene3D G3DSA:1.10.530.10 266 381 9.7E-59 T 06-07-2017 CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Pfam PF13406 Transglycosylase SLT domain 85 376 1.3E-104 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Pfam PF01471 Putative peptidoglycan binding domain 397 452 1.2E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 84 380 2.0E-107 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 SUPERFAMILY SSF53955 74 382 1.8E-96 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS16425 e2c9faee5537f81b4af98eedcb410742 455 Gene3D G3DSA:1.10.101.10 396 453 4.0E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 SMART SM00346 20 108 2.2E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 Gene3D G3DSA:1.10.10.10 17 88 3.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 SUPERFAMILY SSF55781 79 257 4.58E-39 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 SUPERFAMILY SSF46785 20 91 5.72E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 Pfam PF01614 Bacterial transcriptional regulator 135 245 2.7E-29 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 Gene3D G3DSA:3.30.450.40 93 258 4.0E-44 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS17070 2ba21d2581b20a22491a1a7110b32870 264 Pfam PF09339 IclR helix-turn-helix domain 23 69 2.3E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS16120 a6d45398026a5d7076f18d5e5504d9e3 245 Gene3D G3DSA:3.40.50.300 3 242 4.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16120 a6d45398026a5d7076f18d5e5504d9e3 245 SUPERFAMILY SSF52540 4 243 5.11E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16120 a6d45398026a5d7076f18d5e5504d9e3 245 SMART SM00382 30 221 1.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16120 a6d45398026a5d7076f18d5e5504d9e3 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 1.6E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS16120 a6d45398026a5d7076f18d5e5504d9e3 245 Pfam PF00005 ABC transporter 21 173 6.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 PIRSF PIRSF006305 2 200 3.0E-47 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 Hamap MF_00528 Septum formation protein Maf [maf]. 6 199 30.716 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 192 3.8E-41 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 Gene3D G3DSA:3.90.950.10 5 196 3.4E-59 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 SUPERFAMILY SSF52972 5 193 7.19E-55 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK95_RS11320 b4aec5a65ac7772dea77f838b87bac1e 206 Pfam PF02545 Maf-like protein 6 193 5.6E-49 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK95_RS16520 efbfb49b0dd0256d4df0ce20dd620f06 258 Pfam PF13847 Methyltransferase domain 57 171 4.1E-12 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS16520 efbfb49b0dd0256d4df0ce20dd620f06 258 SUPERFAMILY SSF53335 31 166 1.09E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS16520 efbfb49b0dd0256d4df0ce20dd620f06 258 Gene3D G3DSA:3.40.50.150 41 169 6.1E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13965 579c21d349920774e1538828afab47c7 356 SUPERFAMILY SSF53474 40 315 1.79E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13965 579c21d349920774e1538828afab47c7 356 Gene3D G3DSA:3.40.50.1820 51 322 2.5E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13965 579c21d349920774e1538828afab47c7 356 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 73 120 1.5E-7 T 06-07-2017 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 Gene3D G3DSA:1.10.10.60 4 46 8.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 Gene3D G3DSA:1.10.357.10 71 203 3.1E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 Gene3D G3DSA:1.10.10.60 47 70 1.7E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 SUPERFAMILY SSF46689 6 83 6.98E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS14285 7bde6bc2c815b2dc8ed4581a16ef07f8 223 SUPERFAMILY SSF48498 82 201 2.94E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS10100 d6f7d1bc71645d97e3a88282f4460505 179 SUPERFAMILY SSF50475 27 178 3.58E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS10100 d6f7d1bc71645d97e3a88282f4460505 179 SMART SM00903 31 178 4.8E-50 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS10100 d6f7d1bc71645d97e3a88282f4460505 179 Gene3D G3DSA:2.30.110.10 23 177 2.4E-51 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS10100 d6f7d1bc71645d97e3a88282f4460505 179 Pfam PF01613 Flavin reductase like domain 31 179 1.7E-32 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS16180 a4929f4ab532fafbd95dfb70895a10d0 195 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 102 1.1E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS16180 a4929f4ab532fafbd95dfb70895a10d0 195 Gene3D G3DSA:1.20.1290.10 18 153 1.2E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS16180 a4929f4ab532fafbd95dfb70895a10d0 195 SUPERFAMILY SSF69118 15 155 1.1E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS06060 1b483bb1adac80ecc518578b12aae10a 215 Pfam PF03975 CheD chemotactic sensory transduction 79 179 4.9E-27 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CAK95_RS06060 1b483bb1adac80ecc518578b12aae10a 215 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 31 185 26.657 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CAK95_RS06060 1b483bb1adac80ecc518578b12aae10a 215 SUPERFAMILY SSF64438 35 185 1.19E-45 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAK95_RS01470 3de6d5862f4c85af515cab2fb1ea2d89 310 SUPERFAMILY SSF53213 224 306 3.01E-63 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS01470 3de6d5862f4c85af515cab2fb1ea2d89 310 SUPERFAMILY SSF53213 2 185 3.01E-63 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS01470 3de6d5862f4c85af515cab2fb1ea2d89 310 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 302 3.8E-47 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS01470 3de6d5862f4c85af515cab2fb1ea2d89 310 Gene3D G3DSA:3.40.830.10 231 308 1.2E-76 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS01470 3de6d5862f4c85af515cab2fb1ea2d89 310 Gene3D G3DSA:3.40.830.10 2 187 1.2E-76 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS18735 ed076dd16ca6a8a9e2b9a28961bbb199 201 Gene3D G3DSA:3.30.460.10 99 186 1.0E-14 T 06-07-2017 CAK95_RS18735 ed076dd16ca6a8a9e2b9a28961bbb199 201 SUPERFAMILY SSF81301 101 183 7.3E-15 T 06-07-2017 CAK95_RS18735 ed076dd16ca6a8a9e2b9a28961bbb199 201 SUPERFAMILY SSF46785 9 83 2.73E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18735 ed076dd16ca6a8a9e2b9a28961bbb199 201 Pfam PF01909 Nucleotidyltransferase domain 112 149 1.4E-4 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAK95_RS18735 ed076dd16ca6a8a9e2b9a28961bbb199 201 Gene3D G3DSA:1.10.10.10 11 87 3.3E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07580 8c755cf38b9d40f77c73a202989080a2 68 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 1 46 2.1E-12 T 06-07-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 CAK95_RS07580 8c755cf38b9d40f77c73a202989080a2 68 Pfam PF04995 Heme exporter protein D (CcmD) 4 46 1.4E-10 T 06-07-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 CAK95_RS25210 ccfac1bbbcc58bc7793c9fc38c0909d5 174 Pfam PF09335 SNARE associated Golgi protein 38 160 8.9E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK95_RS20630 9b567e39b16924eba4348a82a613238e 250 Pfam PF00994 Probable molybdopterin binding domain 10 168 2.9E-32 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20630 9b567e39b16924eba4348a82a613238e 250 SMART SM00852 10 170 5.8E-29 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20630 9b567e39b16924eba4348a82a613238e 250 Gene3D G3DSA:3.40.980.10 6 205 3.3E-36 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS20630 9b567e39b16924eba4348a82a613238e 250 SUPERFAMILY SSF53218 6 199 2.49E-37 T 06-07-2017 IPR001453 MoaB/Mog domain CAK95_RS23960 072c6e5534da6324a9ea519032bde3de 320 PIRSF PIRSF017082 1 320 6.4E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS23960 072c6e5534da6324a9ea519032bde3de 320 SUPERFAMILY SSF53850 82 284 4.13E-11 T 06-07-2017 CAK95_RS23960 072c6e5534da6324a9ea519032bde3de 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 1.6E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16625 f24ab01c8443afac41f49457a6618ccf 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 242 7.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16625 f24ab01c8443afac41f49457a6618ccf 253 SUPERFAMILY SSF161098 58 237 8.63E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16625 f24ab01c8443afac41f49457a6618ccf 253 Gene3D G3DSA:1.10.3720.10 59 246 4.0E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 SUPERFAMILY SSF51351 6 249 3.27E-87 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 5 250 38.208 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 241 6.5E-61 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 Pfam PF00121 Triosephosphate isomerase 8 246 2.6E-82 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK95_RS23115 4da26cc4012183c9abab5b9723e1884a 251 Gene3D G3DSA:3.20.20.70 6 250 1.0E-91 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS25165 4a45d3efa6a0bd7ac8862529ab24220e 169 SMART SM00260 19 156 7.9E-37 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS25165 4a45d3efa6a0bd7ac8862529ab24220e 169 SUPERFAMILY SSF50341 22 158 6.15E-36 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS25165 4a45d3efa6a0bd7ac8862529ab24220e 169 Gene3D G3DSA:2.40.50.180 61 99 4.7E-8 T 06-07-2017 CAK95_RS25165 4a45d3efa6a0bd7ac8862529ab24220e 169 Pfam PF01584 CheW-like domain 24 158 1.8E-32 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS25165 4a45d3efa6a0bd7ac8862529ab24220e 169 Gene3D G3DSA:2.30.30.40 100 140 2.4E-4 T 06-07-2017 CAK95_RS05985 17aff6db1b4e237012e524f944ae3299 353 SUPERFAMILY SSF51569 22 334 1.65E-31 T 06-07-2017 CAK95_RS05985 17aff6db1b4e237012e524f944ae3299 353 SMART SM01130 17 336 1.6E-9 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05985 17aff6db1b4e237012e524f944ae3299 353 Pfam PF00701 Dihydrodipicolinate synthetase family 32 217 1.4E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS05985 17aff6db1b4e237012e524f944ae3299 353 Gene3D G3DSA:3.20.20.70 22 335 8.4E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS17380 c909b198cdb98ec1e8cf13983334d546 182 SUPERFAMILY SSF117916 29 120 2.16E-21 T 06-07-2017 CAK95_RS17380 c909b198cdb98ec1e8cf13983334d546 182 Pfam PF01883 Domain of unknown function DUF59 35 91 6.0E-13 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAK95_RS17380 c909b198cdb98ec1e8cf13983334d546 182 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 37 182 7.8E-61 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 Pfam PF01743 Poly A polymerase head domain 32 153 5.5E-25 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 186 237 9.4E-7 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 SUPERFAMILY SSF81891 152 410 1.2E-42 T 06-07-2017 CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 Gene3D G3DSA:3.30.460.10 16 150 5.1E-39 T 06-07-2017 CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 SUPERFAMILY SSF81301 11 150 8.83E-38 T 06-07-2017 CAK95_RS00595 5a8ee5a587106458aefa6bb5b67ef79e 418 Gene3D G3DSA:1.10.3090.10 152 376 8.1E-34 T 06-07-2017 CAK95_RS21730 d652d4ca080a118ffa43c3629fc7211e 155 SUPERFAMILY SSF54637 10 142 1.12E-30 T 06-07-2017 IPR029069 HotDog domain CAK95_RS21730 d652d4ca080a118ffa43c3629fc7211e 155 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 124 4.0E-16 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS21730 d652d4ca080a118ffa43c3629fc7211e 155 Pfam PF03061 Thioesterase superfamily 55 122 2.6E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS21730 d652d4ca080a118ffa43c3629fc7211e 155 Gene3D G3DSA:3.10.129.10 13 143 1.6E-34 T 06-07-2017 IPR029069 HotDog domain CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 Pfam PF01070 FMN-dependent dehydrogenase 39 399 3.1E-105 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 PIRSF PIRSF000138 17 406 3.2E-101 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 SUPERFAMILY SSF51395 251 400 5.5E-78 T 06-07-2017 CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 SUPERFAMILY SSF51395 29 222 5.5E-78 T 06-07-2017 CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 Gene3D G3DSA:3.20.20.70 31 403 2.8E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS22465 d6805f1db20daf80ecc647df9657eef4 411 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 301 307 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAK95_RS14405 eb6c6fe83c78e2f069cddd9d5b4a0d9e 85 Pfam PF04226 Transglycosylase associated protein 36 83 8.2E-12 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS13550 c9c5de48424e5517d472b0a5f65ccf04 322 SUPERFAMILY SSF103481 205 302 2.88E-8 T 06-07-2017 CAK95_RS13550 c9c5de48424e5517d472b0a5f65ccf04 322 Pfam PF00892 EamA-like transporter family 26 150 7.8E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS13550 c9c5de48424e5517d472b0a5f65ccf04 322 Pfam PF00892 EamA-like transporter family 170 301 1.0E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS13550 c9c5de48424e5517d472b0a5f65ccf04 322 SUPERFAMILY SSF103481 61 152 2.75E-7 T 06-07-2017 CAK95_RS22290 6b403e41ae8a8148f70d870021154a89 335 SUPERFAMILY SSF53850 124 295 3.53E-8 T 06-07-2017 CAK95_RS22290 6b403e41ae8a8148f70d870021154a89 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 330 5.7E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS22290 6b403e41ae8a8148f70d870021154a89 335 PIRSF PIRSF017082 1 335 1.5E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00705 ee23c11a74842a28ae791c7057b1b6dd 96 Pfam PF11373 Protein of unknown function (DUF3175) 11 95 1.5E-39 T 06-07-2017 IPR021513 Ralstonia phage RSL1, Orf186 CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 SUPERFAMILY SSF51430 13 288 3.67E-63 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 Pfam PF00248 Aldo/keto reductase family 19 287 3.9E-48 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 Gene3D G3DSA:3.20.20.100 14 288 4.2E-60 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 PRINTS PR00069 Aldo-keto reductase signature 220 244 3.4E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 PRINTS PR00069 Aldo-keto reductase signature 49 73 3.4E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS16580 e738a6b203c5947f60d68b11fc9d86b8 294 PRINTS PR00069 Aldo-keto reductase signature 150 167 3.4E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS19955 0d251259dc5a42566780ab2343e02738 462 Pfam PF01474 Class-II DAHP synthetase family 5 442 8.4E-205 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK95_RS19955 0d251259dc5a42566780ab2343e02738 462 SUPERFAMILY SSF51569 3 446 1.68E-204 T 06-07-2017 CAK95_RS19955 0d251259dc5a42566780ab2343e02738 462 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 5 448 4.5E-221 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK95_RS05250 5a722deda59a66e3441355211fa4da7c 227 Gene3D G3DSA:2.60.450.10 41 191 7.8E-35 T 06-07-2017 CAK95_RS05250 5a722deda59a66e3441355211fa4da7c 227 Pfam PF03968 OstA-like protein 49 175 2.0E-20 T 06-07-2017 IPR005653 Organic solvent tolerance-like, N-terminal CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 SUPERFAMILY SSF75615 109 201 1.7E-24 T 06-07-2017 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Pfam PF10414 Sirohaem synthase dimerisation region 146 198 4.7E-10 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 215 424 6.5E-48 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Pfam PF14824 Sirohaem biosynthesis protein central 114 140 3.3E-7 T 06-07-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Gene3D G3DSA:3.30.950.10 329 449 1.7E-33 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 SUPERFAMILY SSF53790 210 446 3.53E-68 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Gene3D G3DSA:3.40.1010.10 212 328 1.2E-41 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 198 8.4E-43 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 SUPERFAMILY SSF51735 1 108 2.76E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Pfam PF13241 Putative NAD(P)-binding 6 110 9.5E-11 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 293 326 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Gene3D G3DSA:3.40.50.720 1 107 1.9E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 218 232 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Gene3D G3DSA:3.30.160.110 108 143 8.5E-20 T 06-07-2017 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 213 447 1.2E-79 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 Gene3D G3DSA:1.10.8.210 146 203 8.5E-10 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS24705 ccf4396d319ae28ed99d7fa8a6fc100c 461 PIRSF PIRSF036426 1 460 7.9E-153 T 06-07-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK95_RS08470 13fbb301416b5584368477decdc8c379 172 Gene3D G3DSA:2.40.440.10 37 171 1.9E-33 T 06-07-2017 CAK95_RS08470 13fbb301416b5584368477decdc8c379 172 Pfam PF03734 L,D-transpeptidase catalytic domain 43 170 1.0E-18 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS08470 13fbb301416b5584368477decdc8c379 172 SUPERFAMILY SSF141523 36 171 9.68E-31 T 06-07-2017 CAK95_RS26425 e00e61acb3fbbbd7bec43710471f7df4 403 SUPERFAMILY SSF89796 7 396 9.55E-127 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS26425 e00e61acb3fbbbd7bec43710471f7df4 403 Gene3D G3DSA:3.40.50.10540 6 221 7.2E-109 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS26425 e00e61acb3fbbbd7bec43710471f7df4 403 Gene3D G3DSA:3.40.50.10540 310 395 7.2E-109 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS26425 e00e61acb3fbbbd7bec43710471f7df4 403 Gene3D G3DSA:3.30.1540.10 238 309 7.7E-27 T 06-07-2017 CAK95_RS26425 e00e61acb3fbbbd7bec43710471f7df4 403 Pfam PF02515 CoA-transferase family III 10 377 9.9E-113 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS24045 df27594c6a5dbb4798b4ef5790c91b94 659 SUPERFAMILY SSF53649 278 596 5.67E-59 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS24045 df27594c6a5dbb4798b4ef5790c91b94 659 Gene3D G3DSA:3.40.720.10 279 575 9.9E-38 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS24045 df27594c6a5dbb4798b4ef5790c91b94 659 Pfam PF00884 Sulfatase 279 563 2.4E-37 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS24045 df27594c6a5dbb4798b4ef5790c91b94 659 PIRSF PIRSF005091 20 604 6.6E-79 T 06-07-2017 IPR012160 Lipoteichoic acid synthase-like CAK95_RS11205 b5ff09927d48345bef5b668e55e41453 401 Pfam PF04055 Radical SAM superfamily 114 292 1.8E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS11205 b5ff09927d48345bef5b668e55e41453 401 SMART SM00729 110 335 1.2E-5 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS11205 b5ff09927d48345bef5b668e55e41453 401 Gene3D G3DSA:3.20.20.70 114 299 8.6E-9 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS11205 b5ff09927d48345bef5b668e55e41453 401 SUPERFAMILY SSF102114 95 301 2.35E-11 T 06-07-2017 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 SUPERFAMILY SSF53474 51 339 1.43E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 PRINTS PR00412 Epoxide hydrolase signature 77 95 1.2E-14 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 PRINTS PR00412 Epoxide hydrolase signature 159 172 1.2E-14 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 PRINTS PR00412 Epoxide hydrolase signature 97 112 1.2E-14 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 PRINTS PR00412 Epoxide hydrolase signature 145 158 1.2E-14 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 PRINTS PR00412 Epoxide hydrolase signature 318 340 1.2E-14 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 Pfam PF00561 alpha/beta hydrolase fold 71 199 1.4E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS26180 635f3878d7e8ca563575a2c21325b540 343 Gene3D G3DSA:3.40.50.1820 51 339 3.2E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20525 225a745e1ec42266f75b7108b3e10f36 279 Pfam PF13505 Outer membrane protein beta-barrel domain 34 279 4.6E-21 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS20525 225a745e1ec42266f75b7108b3e10f36 279 Gene3D G3DSA:2.40.160.20 33 279 7.5E-33 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS20525 225a745e1ec42266f75b7108b3e10f36 279 SUPERFAMILY SSF56925 40 279 5.23E-29 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS11325 5248d505ccbf87b5e3397365a1029793 67 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 7 57 16.752 T 06-07-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 CAK95_RS11325 5248d505ccbf87b5e3397365a1029793 67 Pfam PF03884 Domain of unknown function (DUF329) 12 56 9.1E-15 T 06-07-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 CAK95_RS11325 5248d505ccbf87b5e3397365a1029793 67 SUPERFAMILY SSF57716 11 59 2.0E-14 T 06-07-2017 CAK95_RS11325 5248d505ccbf87b5e3397365a1029793 67 Gene3D G3DSA:3.30.50.10 10 58 1.8E-19 T 06-07-2017 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 CAK95_RS14300 04f9c724768cbb18accf40bc062ea8dc 337 SUPERFAMILY SSF51556 22 337 1.98E-81 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS14300 04f9c724768cbb18accf40bc062ea8dc 337 Gene3D G3DSA:3.20.20.140 23 337 6.1E-91 T 06-07-2017 CAK95_RS14300 04f9c724768cbb18accf40bc062ea8dc 337 Pfam PF04909 Amidohydrolase 62 337 2.2E-46 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS06460 9307c0cda07fcc7c4de94117372fc341 162 Pfam PF01899 Na+/H+ ion antiporter subunit 12 160 1.6E-43 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CAK95_RS06460 9307c0cda07fcc7c4de94117372fc341 162 PIRSF PIRSF019239 1 162 4.0E-41 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 PIRSF PIRSF000545 1 317 1.2E-143 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 SUPERFAMILY SSF52540 8 315 4.18E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 Hamap MF_00215 Pantothenate kinase [coaA]. 1 317 180.863 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 90 243 1.2E-11 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 11 316 5.9E-130 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK95_RS08810 e45b7ee5fce9e3fb2a0b4d8a2cf8727c 317 Gene3D G3DSA:3.40.50.300 10 315 2.9E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15975 bc4c5f75edad512d44de2706a82ac29e 356 SUPERFAMILY SSF51182 23 354 1.06E-101 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS15975 bc4c5f75edad512d44de2706a82ac29e 356 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 23 355 2.6E-145 T 06-07-2017 IPR011960 Gentisate 1,2-dioxygenase CAK95_RS15975 bc4c5f75edad512d44de2706a82ac29e 356 Gene3D G3DSA:2.60.120.10 53 212 2.7E-43 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15975 bc4c5f75edad512d44de2706a82ac29e 356 Gene3D G3DSA:2.60.120.10 224 354 1.9E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15975 bc4c5f75edad512d44de2706a82ac29e 356 Pfam PF07883 Cupin domain 107 175 1.8E-21 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 SUPERFAMILY SSF53335 57 410 1.02E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 342 372 - T 06-07-2017 IPR030390 RNA methyltransferase TrmA, active site CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 SUPERFAMILY SSF50249 4 49 3.43E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 261 403 1.3E-9 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 Gene3D G3DSA:3.40.50.150 232 410 2.4E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15905 4645c1168028edc6f787531e9f767af8 410 Gene3D G3DSA:2.40.50.140 5 69 4.1E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.2E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 SUPERFAMILY SSF56645 5 246 1.96E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 SUPERFAMILY SSF47203 232 387 3.22E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 118 1.3E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 367 1.3E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Gene3D G3DSA:1.20.140.10 224 388 8.5E-57 T 06-07-2017 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Gene3D G3DSA:2.40.110.10 123 223 3.3E-31 T 06-07-2017 CAK95_RS27165 17a9ac1b7ff9a7f10ea23e29b1baefc3 389 Gene3D G3DSA:1.10.540.10 6 119 1.1E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 SUPERFAMILY SSF46785 6 96 5.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 5.7E-16 T 06-07-2017 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 Gene3D G3DSA:1.10.10.10 8 58 2.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 SMART SM00344 7 116 4.1E-33 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 Pfam PF01037 Lrp/AsnC ligand binding domain 75 147 1.8E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 SUPERFAMILY SSF54909 67 156 1.88E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS17440 9599441ba08e57f1ff21361c637b7539 157 Gene3D G3DSA:3.30.70.920 60 156 5.9E-26 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 SUPERFAMILY SSF48008 76 211 1.91E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 SMART SM00345 13 71 1.4E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 Pfam PF07729 FCD domain 81 204 2.9E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 1.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 SUPERFAMILY SSF46785 9 97 1.09E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 SMART SM00895 81 205 6.2E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 Gene3D G3DSA:1.10.10.10 9 73 2.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04975 c7c65cce7f5a51f9e1361b8465ac57df 236 Gene3D G3DSA:1.20.120.530 75 211 2.8E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS18340 c1ed2100a100648226bc5ca4d7814965 236 SUPERFAMILY SSF52833 1 83 1.48E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS18340 c1ed2100a100648226bc5ca4d7814965 236 Gene3D G3DSA:1.20.1050.10 102 206 8.0E-54 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS18340 c1ed2100a100648226bc5ca4d7814965 236 SUPERFAMILY SSF47616 83 235 1.05E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS18340 c1ed2100a100648226bc5ca4d7814965 236 Gene3D G3DSA:3.40.30.10 1 101 3.3E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS18340 c1ed2100a100648226bc5ca4d7814965 236 Pfam PF14497 Glutathione S-transferase, C-terminal domain 110 217 5.5E-31 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 Pfam PF12802 MarR family 43 100 8.7E-14 T 06-07-2017 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 3.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 3.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 3.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 3.8E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 SMART SM00347 37 137 2.0E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 SUPERFAMILY SSF46785 6 150 4.92E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00250 0e8bf234e92767411c70b467f9c90f81 160 Gene3D G3DSA:1.10.10.10 5 150 2.3E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00800 1bc5f270d6db9428424b605896884e87 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 319 6.5E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00800 1bc5f270d6db9428424b605896884e87 323 SUPERFAMILY SSF53850 110 283 1.09E-6 T 06-07-2017 CAK95_RS00800 1bc5f270d6db9428424b605896884e87 323 PIRSF PIRSF017082 1 323 2.4E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18015 8ce272fbc7b55357ebbf43a183aa1d36 359 Pfam PF13692 Glycosyl transferases group 1 179 297 4.1E-19 T 06-07-2017 CAK95_RS18015 8ce272fbc7b55357ebbf43a183aa1d36 359 SUPERFAMILY SSF53756 1 326 8.9E-66 T 06-07-2017 CAK95_RS18015 8ce272fbc7b55357ebbf43a183aa1d36 359 Pfam PF13439 Glycosyltransferase Family 4 15 163 1.8E-13 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS18015 8ce272fbc7b55357ebbf43a183aa1d36 359 Gene3D G3DSA:3.40.50.2000 175 298 3.4E-19 T 06-07-2017 CAK95_RS20430 0ac46406d32f85a577e92a43c47f3d66 310 Pfam PF00005 ABC transporter 25 166 6.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS20430 0ac46406d32f85a577e92a43c47f3d66 310 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS20430 0ac46406d32f85a577e92a43c47f3d66 310 SMART SM00382 33 212 6.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS20430 0ac46406d32f85a577e92a43c47f3d66 310 SUPERFAMILY SSF52540 8 229 5.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20430 0ac46406d32f85a577e92a43c47f3d66 310 Gene3D G3DSA:3.40.50.300 4 228 2.7E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00215 3b9c399765604e1413cf6f07896435ac 295 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 220 294 3.0E-17 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS00215 3b9c399765604e1413cf6f07896435ac 295 Gene3D G3DSA:3.30.1150.10 186 295 6.5E-21 T 06-07-2017 CAK95_RS00215 3b9c399765604e1413cf6f07896435ac 295 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 218 293 6.4E-14 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAK95_RS00215 3b9c399765604e1413cf6f07896435ac 295 SUPERFAMILY SSF74653 194 294 5.1E-20 T 06-07-2017 CAK95_RS24750 66f14e215d5e1d1b3cfb31117f26d56d 320 Pfam PF09084 NMT1/THI5 like 47 250 3.4E-21 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS24750 66f14e215d5e1d1b3cfb31117f26d56d 320 SUPERFAMILY SSF53850 37 257 2.51E-29 T 06-07-2017 CAK95_RS24750 66f14e215d5e1d1b3cfb31117f26d56d 320 Gene3D G3DSA:3.40.190.10 117 235 3.0E-12 T 06-07-2017 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 Pfam PF01220 Dehydroquinase class II 5 141 3.0E-49 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 PIRSF PIRSF001399 2 148 1.6E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 SUPERFAMILY SSF52304 5 149 1.18E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 Gene3D G3DSA:3.40.50.9100 4 145 2.6E-55 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 156 61.716 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS16915 ebaccb3e75bf9d1d4895382b0cd10685 156 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 6 141 8.0E-40 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS26460 341597deca2401824efb8068e25d62ac 1173 SMART SM00869 902 1162 5.8E-46 T 06-07-2017 IPR005546 Autotransporter beta-domain CAK95_RS26460 341597deca2401824efb8068e25d62ac 1173 Pfam PF03797 Autotransporter beta-domain 902 1156 2.6E-46 T 06-07-2017 IPR005546 Autotransporter beta-domain CAK95_RS26460 341597deca2401824efb8068e25d62ac 1173 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 878 1173 4.4E-26 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAK95_RS26460 341597deca2401824efb8068e25d62ac 1173 Gene3D G3DSA:2.40.128.130 900 1173 6.6E-51 T 06-07-2017 IPR005546 Autotransporter beta-domain CAK95_RS26460 341597deca2401824efb8068e25d62ac 1173 SUPERFAMILY SSF103515 898 1173 3.14E-51 T 06-07-2017 IPR005546 Autotransporter beta-domain CAK95_RS02100 63e21a419004037751b5aa0eb144c7e2 168 SUPERFAMILY SSF54427 13 168 9.43E-35 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS02100 63e21a419004037751b5aa0eb144c7e2 168 Gene3D G3DSA:3.10.450.50 11 161 6.4E-23 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS02100 63e21a419004037751b5aa0eb144c7e2 168 Pfam PF00866 Ring hydroxylating beta subunit 28 160 9.9E-9 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAK95_RS06580 559774ff67fbf77f38b49667780b3fca 213 SUPERFAMILY SSF53448 10 202 1.42E-31 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS06580 559774ff67fbf77f38b49667780b3fca 213 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 8 202 27.424 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 CAK95_RS06580 559774ff67fbf77f38b49667780b3fca 213 Pfam PF12804 MobA-like NTP transferase domain 12 167 2.6E-36 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK95_RS06580 559774ff67fbf77f38b49667780b3fca 213 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 12 198 3.6E-64 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 CAK95_RS06580 559774ff67fbf77f38b49667780b3fca 213 Gene3D G3DSA:3.90.550.10 11 208 2.5E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26235 f9b235c595ec12fed8a966b393ab10a1 406 SUPERFAMILY SSF46785 334 386 1.53E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS26235 f9b235c595ec12fed8a966b393ab10a1 406 Gene3D G3DSA:1.10.10.10 335 372 1.8E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20435 b8dbcf9f05bbedb9e5edcb6254cc5995 389 Pfam PF12698 ABC-2 family transporter protein 43 380 8.5E-46 T 06-07-2017 CAK95_RS22750 68f815e872bb00a9118f0b20a0594742 228 SUPERFAMILY SSF51197 3 179 1.65E-6 T 06-07-2017 CAK95_RS22750 68f815e872bb00a9118f0b20a0594742 228 SMART SM00702 1 178 4.7E-16 T 06-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CAK95_RS22750 68f815e872bb00a9118f0b20a0594742 228 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 177 1.3E-12 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS22750 68f815e872bb00a9118f0b20a0594742 228 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 228 44.328 T 06-07-2017 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PIRSF PIRSF000126 1 266 4.3E-73 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 0.0087 T 06-07-2017 CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 SUPERFAMILY SSF51735 4 233 2.32E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 Pfam PF00106 short chain dehydrogenase 9 197 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25370 dbc23bc05f29a7d022e3bbad88472d2b 266 Gene3D G3DSA:3.40.50.720 9 227 1.0E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS03275 d87d144606d7ed7fb04b09c2acc76e71 396 Gene3D G3DSA:3.40.50.2300 34 158 3.1E-42 T 06-07-2017 CAK95_RS03275 d87d144606d7ed7fb04b09c2acc76e71 396 Gene3D G3DSA:3.40.50.2300 310 363 3.1E-42 T 06-07-2017 CAK95_RS03275 d87d144606d7ed7fb04b09c2acc76e71 396 Pfam PF13458 Periplasmic binding protein 35 375 2.8E-74 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS03275 d87d144606d7ed7fb04b09c2acc76e71 396 Gene3D G3DSA:3.40.50.2300 160 309 7.6E-26 T 06-07-2017 CAK95_RS03275 d87d144606d7ed7fb04b09c2acc76e71 396 SUPERFAMILY SSF53822 35 388 7.74E-90 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS05945 4ea75750536340e4e0734c73b8402c62 291 Pfam PF00583 Acetyltransferase (GNAT) family 55 125 5.0E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS05945 4ea75750536340e4e0734c73b8402c62 291 Gene3D G3DSA:3.40.630.30 16 127 2.6E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS05945 4ea75750536340e4e0734c73b8402c62 291 SUPERFAMILY SSF55729 14 255 3.63E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS04110 55863022aa6567dd4137fd488f48f30e 273 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 255 8.7E-78 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like CAK95_RS04110 55863022aa6567dd4137fd488f48f30e 273 Pfam PF13277 YmdB-like protein 4 257 5.8E-101 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like CAK95_RS04110 55863022aa6567dd4137fd488f48f30e 273 Gene3D G3DSA:3.60.21.30 1 271 1.8E-109 T 06-07-2017 CAK95_RS04110 55863022aa6567dd4137fd488f48f30e 273 PIRSF PIRSF004789 1 265 1.4E-87 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like CAK95_RS04110 55863022aa6567dd4137fd488f48f30e 273 SUPERFAMILY SSF56300 1 259 1.0E-83 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 Gene3D G3DSA:3.40.190.10 90 175 6.9E-16 T 06-07-2017 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 Gene3D G3DSA:1.10.10.10 5 86 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 SUPERFAMILY SSF53850 91 294 9.15E-26 T 06-07-2017 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 Gene3D G3DSA:3.40.190.10 176 262 4.7E-14 T 06-07-2017 CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 SUPERFAMILY SSF46785 5 86 1.91E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02395 5c13550805a2e3c61b7bf5d9bee419a9 321 Pfam PF03466 LysR substrate binding domain 89 294 4.8E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS11495 d699a8cd9b9a966363a03cea6be2a089 264 SUPERFAMILY SSF52096 2 258 5.55E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS11495 d699a8cd9b9a966363a03cea6be2a089 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 4.6E-56 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS11495 d699a8cd9b9a966363a03cea6be2a089 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS11495 d699a8cd9b9a966363a03cea6be2a089 264 Gene3D G3DSA:3.90.226.10 3 257 2.5E-71 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 SUPERFAMILY SSF56784 83 290 2.67E-44 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 76 286 2.9E-66 T 06-07-2017 CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 Gene3D G3DSA:1.10.150.210 93 143 6.8E-25 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 Pfam PF12710 haloacid dehalogenase-like hydrolase 85 252 6.0E-16 T 06-07-2017 CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 Gene3D G3DSA:3.40.50.1000 144 285 1.2E-37 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS14635 1e79d22fe5ca350d16d47bb6f57f6552 302 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 83 255 1.4E-30 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAK95_RS28650 69afd2cc7a2c13c6e28b3bf08122cd5f 285 Gene3D G3DSA:3.40.50.300 30 243 3.7E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28650 69afd2cc7a2c13c6e28b3bf08122cd5f 285 SMART SM00382 57 241 1.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS28650 69afd2cc7a2c13c6e28b3bf08122cd5f 285 SUPERFAMILY SSF52540 36 260 3.41E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28650 69afd2cc7a2c13c6e28b3bf08122cd5f 285 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28650 69afd2cc7a2c13c6e28b3bf08122cd5f 285 Pfam PF00005 ABC transporter 48 190 3.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 SUPERFAMILY SSF48452 451 655 1.77E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 Pfam PF03704 Bacterial transcriptional activator domain 114 245 3.0E-8 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 Gene3D G3DSA:1.25.40.10 452 655 8.9E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 Gene3D G3DSA:1.25.40.10 188 226 4.5E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 SMART SM01043 121 259 7.8E-14 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 SUPERFAMILY SSF48452 141 244 5.69E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS00030 7e115633e33c7f9d577c8f62bcea9f71 685 Pfam PF13432 Tetratricopeptide repeat 523 572 0.0025 T 06-07-2017 CAK95_RS27450 afc93a4cfb0ce9c9f202310f9359e463 286 SUPERFAMILY SSF53335 47 214 8.47E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27450 afc93a4cfb0ce9c9f202310f9359e463 286 Gene3D G3DSA:3.40.50.150 154 262 8.4E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27450 afc93a4cfb0ce9c9f202310f9359e463 286 SUPERFAMILY SSF53335 150 279 2.84E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27450 afc93a4cfb0ce9c9f202310f9359e463 286 Pfam PF08241 Methyltransferase domain 119 200 4.7E-13 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS18885 f56f215ec043769927c46c0905071553 182 PIRSF PIRSF010244 1 182 4.0E-30 T 06-07-2017 IPR014456 Uncharacterised conserved protein UCP010244, integral membrane protein CAK95_RS18885 f56f215ec043769927c46c0905071553 182 Pfam PF06863 Protein of unknown function (DUF1254) 70 172 3.8E-6 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS13815 d6ffba01303fcd77dabcdbf2f83c0c39 280 SUPERFAMILY SSF53335 74 264 2.66E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13815 d6ffba01303fcd77dabcdbf2f83c0c39 280 Gene3D G3DSA:3.40.50.150 85 261 8.9E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13815 d6ffba01303fcd77dabcdbf2f83c0c39 280 Pfam PF08241 Methyltransferase domain 94 189 2.0E-11 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS12105 b8e13484f9dbe47b40976ce88397d81d 126 SUPERFAMILY SSF52172 1 120 1.71E-30 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS12105 b8e13484f9dbe47b40976ce88397d81d 126 Gene3D G3DSA:3.40.50.2300 1 122 1.8E-31 T 06-07-2017 CAK95_RS12105 b8e13484f9dbe47b40976ce88397d81d 126 Pfam PF00072 Response regulator receiver domain 4 115 8.3E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS12105 b8e13484f9dbe47b40976ce88397d81d 126 SMART SM00448 2 115 1.2E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS02570 20b0f13bb0649fbf7e57de7393c6cef5 349 Pfam PF13362 Toprim domain 239 326 9.1E-20 T 06-07-2017 IPR006171 Toprim domain CAK95_RS02570 20b0f13bb0649fbf7e57de7393c6cef5 349 Gene3D G3DSA:3.40.1360.10 261 334 6.2E-4 T 06-07-2017 CAK95_RS20585 24a80619bba4fdb54a797428bf334203 384 Pfam PF07690 Major Facilitator Superfamily 15 327 3.2E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS20585 24a80619bba4fdb54a797428bf334203 384 SUPERFAMILY SSF103473 5 376 2.49E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS20585 24a80619bba4fdb54a797428bf334203 384 Gene3D G3DSA:1.20.1250.20 8 182 3.1E-23 T 06-07-2017 CAK95_RS20585 24a80619bba4fdb54a797428bf334203 384 Gene3D G3DSA:1.20.1250.20 199 373 3.8E-13 T 06-07-2017 CAK95_RS04820 e73a6bc43eef216db4a3ddaadc26895a 163 Pfam PF04542 Sigma-70 region 2 7 72 6.7E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS04820 e73a6bc43eef216db4a3ddaadc26895a 163 Gene3D G3DSA:1.10.1740.10 5 94 6.2E-12 T 06-07-2017 CAK95_RS04820 e73a6bc43eef216db4a3ddaadc26895a 163 SUPERFAMILY SSF88946 5 91 5.89E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS15585 440df7319c0fc77cdeb31cf92ce96da2 348 PIRSF PIRSF000164 1 327 4.2E-26 T 06-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CAK95_RS15585 440df7319c0fc77cdeb31cf92ce96da2 348 SUPERFAMILY SSF51395 4 317 7.94E-38 T 06-07-2017 CAK95_RS15585 440df7319c0fc77cdeb31cf92ce96da2 348 Gene3D G3DSA:3.20.20.70 4 318 1.0E-37 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS15585 440df7319c0fc77cdeb31cf92ce96da2 348 Pfam PF01180 Dihydroorotate dehydrogenase 89 301 2.8E-11 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAK95_RS16955 453fdd8a1e4f54219a4264f573be89ff 318 Gene3D G3DSA:1.10.3720.10 109 314 6.8E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16955 453fdd8a1e4f54219a4264f573be89ff 318 SUPERFAMILY SSF161098 115 303 1.96E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16955 453fdd8a1e4f54219a4264f573be89ff 318 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 48 92 6.1E-6 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAK95_RS16955 453fdd8a1e4f54219a4264f573be89ff 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 317 3.8E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23515 3cc0c82043da8344663d6deee4c745e9 307 SUPERFAMILY SSF53474 81 203 2.01E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23515 3cc0c82043da8344663d6deee4c745e9 307 Gene3D G3DSA:3.40.50.1820 79 203 4.1E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23515 3cc0c82043da8344663d6deee4c745e9 307 Gene3D G3DSA:3.10.350.10 246 286 4.9E-7 T 06-07-2017 IPR018392 LysM domain CAK95_RS23515 3cc0c82043da8344663d6deee4c745e9 307 SUPERFAMILY SSF54106 246 286 1.96E-5 T 06-07-2017 IPR018392 LysM domain CAK95_RS23515 3cc0c82043da8344663d6deee4c745e9 307 Pfam PF01476 LysM domain 247 286 9.0E-5 T 06-07-2017 IPR018392 LysM domain CAK95_RS03430 12e0404cb23d43f367b0e358970b5b35 271 Gene3D G3DSA:1.10.10.10 17 76 4.9E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03430 12e0404cb23d43f367b0e358970b5b35 271 Pfam PF13730 Helix-turn-helix domain 17 70 6.3E-9 T 06-07-2017 CAK95_RS01010 c47307c71aae2409e8952b06e02e54a6 151 Gene3D G3DSA:3.10.129.10 9 146 7.9E-25 T 06-07-2017 IPR029069 HotDog domain CAK95_RS01010 c47307c71aae2409e8952b06e02e54a6 151 SUPERFAMILY SSF54637 11 146 5.38E-21 T 06-07-2017 IPR029069 HotDog domain CAK95_RS20575 02b55619ca8aa379becd16d4c733df08 307 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 303 1.4E-55 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20575 02b55619ca8aa379becd16d4c733df08 307 SUPERFAMILY SSF56529 77 305 4.84E-59 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS20575 02b55619ca8aa379becd16d4c733df08 307 Gene3D G3DSA:3.90.850.10 73 306 1.2E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS04825 2add54048760c066f082c54f92548366 69 Pfam PF01381 Helix-turn-helix 12 65 4.9E-20 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS04825 2add54048760c066f082c54f92548366 69 SMART SM00530 11 66 4.2E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS04825 2add54048760c066f082c54f92548366 69 Gene3D G3DSA:1.10.260.40 2 68 1.6E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS04825 2add54048760c066f082c54f92548366 69 SUPERFAMILY SSF47413 2 67 5.09E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS17275 514e4da88819be1e813a41dbacfab02d 240 Gene3D G3DSA:3.40.50.10320 2 237 1.7E-39 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK95_RS17275 514e4da88819be1e813a41dbacfab02d 240 SUPERFAMILY SSF102588 4 238 1.29E-46 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK95_RS17275 514e4da88819be1e813a41dbacfab02d 240 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 134 9.9E-22 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 Pfam PF01494 FAD binding domain 11 355 2.4E-26 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 SUPERFAMILY SSF54373 186 283 1.9E-21 T 06-07-2017 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 SUPERFAMILY SSF51905 11 181 1.38E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 SUPERFAMILY SSF51905 280 367 1.38E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 Gene3D G3DSA:3.50.50.60 11 187 1.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 Gene3D G3DSA:3.50.50.60 280 357 1.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 1.1E-17 T 06-07-2017 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 1.1E-17 T 06-07-2017 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 1.1E-17 T 06-07-2017 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 1.1E-17 T 06-07-2017 CAK95_RS01385 4c6201b8f87e63c82b7844ec480a010c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 1.1E-17 T 06-07-2017 CAK95_RS02225 48604b752083a4467c4a947f8246133d 120 Gene3D G3DSA:2.102.10.10 3 119 3.2E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02225 48604b752083a4467c4a947f8246133d 120 Pfam PF00355 Rieske [2Fe-2S] domain 4 100 3.4E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS02225 48604b752083a4467c4a947f8246133d 120 SUPERFAMILY SSF50022 4 120 1.31E-23 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 9 380 2.1E-117 T 06-07-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 Gene3D G3DSA:3.40.630.10 326 385 1.2E-60 T 06-07-2017 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 Gene3D G3DSA:3.40.630.10 3 185 1.2E-60 T 06-07-2017 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 140 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 SUPERFAMILY SSF55031 177 283 7.85E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 Pfam PF01546 Peptidase family M20/M25/M40 70 381 1.8E-32 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 SUPERFAMILY SSF53187 4 176 5.71E-56 T 06-07-2017 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 SUPERFAMILY SSF53187 306 384 5.71E-56 T 06-07-2017 CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 Pfam PF07687 Peptidase dimerisation domain 173 281 2.1E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS16860 d9743a95787d83d46242d236b42bf8f6 394 Gene3D G3DSA:3.30.70.360 186 282 3.3E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS14945 f5b0f749c56bfda1dff2fcac241237f7 381 SUPERFAMILY SSF53822 25 379 3.39E-72 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS14945 f5b0f749c56bfda1dff2fcac241237f7 381 Pfam PF13458 Periplasmic binding protein 26 374 1.9E-53 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS14945 f5b0f749c56bfda1dff2fcac241237f7 381 Gene3D G3DSA:3.40.50.2300 25 215 8.0E-46 T 06-07-2017 CAK95_RS02485 11246e2d2a541e728010995f359a2dfa 111 Pfam PF05284 Protein of unknown function (DUF736) 3 104 1.7E-37 T 06-07-2017 IPR007948 Protein of unknown function DUF736 CAK95_RS26540 ad64d3ccf5e1fb9e790a349f8c3c0648 258 SUPERFAMILY SSF51621 9 255 3.45E-64 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26540 ad64d3ccf5e1fb9e790a349f8c3c0648 258 Gene3D G3DSA:3.20.20.60 8 255 8.4E-65 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS26540 ad64d3ccf5e1fb9e790a349f8c3c0648 258 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 23 245 2.2E-29 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 SUPERFAMILY SSF53697 127 310 4.45E-39 T 06-07-2017 CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 Pfam PF01418 Helix-turn-helix domain, rpiR family 38 110 2.8E-17 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 Pfam PF01380 SIS domain 159 287 2.6E-19 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 SUPERFAMILY SSF46689 37 112 2.51E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 Gene3D G3DSA:1.10.10.10 37 111 1.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00965 96f198528ebd613637b9c38a20672c24 313 Gene3D G3DSA:3.40.50.10490 128 294 6.2E-36 T 06-07-2017 CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 Gene3D G3DSA:1.10.357.10 12 191 1.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 SUPERFAMILY SSF48498 101 188 7.28E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS07280 825f92dbead1db45f6577d95d72036f2 209 SUPERFAMILY SSF46689 7 83 3.49E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 SMART SM00388 258 316 3.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 3.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 3.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 3.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 Gene3D G3DSA:3.30.565.10 302 461 3.8E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 Gene3D G3DSA:1.10.287.130 251 301 1.4E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 SUPERFAMILY SSF55874 309 461 2.36E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 Pfam PF00672 HAMP domain 187 252 1.5E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 460 3.3E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 SUPERFAMILY SSF47384 242 316 1.45E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK95_RS01665 27ccd6d1c2915f2ab35b5f4b5bb791b8 461 SMART SM00387 354 461 6.6E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS28865 21cbad59d97033a43f6a0ec88cb6d896 323 Pfam PF09084 NMT1/THI5 like 54 255 1.2E-13 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS28865 21cbad59d97033a43f6a0ec88cb6d896 323 SUPERFAMILY SSF53850 40 257 2.25E-21 T 06-07-2017 CAK95_RS28865 21cbad59d97033a43f6a0ec88cb6d896 323 Gene3D G3DSA:3.40.190.10 245 259 5.3E-8 T 06-07-2017 CAK95_RS28865 21cbad59d97033a43f6a0ec88cb6d896 323 Gene3D G3DSA:3.40.190.10 109 205 5.3E-8 T 06-07-2017 CAK95_RS08520 5a45193a54464d461b8095664c78e90a 208 SUPERFAMILY SSF140478 39 195 6.02E-53 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS08520 5a45193a54464d461b8095664c78e90a 208 Gene3D G3DSA:1.20.1440.20 26 208 5.1E-61 T 06-07-2017 IPR023353 LemA-like domain CAK95_RS08520 5a45193a54464d461b8095664c78e90a 208 Pfam PF04011 LemA family 21 208 5.7E-64 T 06-07-2017 IPR007156 LemA CAK95_RS21330 43a20b8e8acd46e1b70f70afcb1f6779 101 SUPERFAMILY SSF57716 2 101 1.92E-34 T 06-07-2017 CAK95_RS21330 43a20b8e8acd46e1b70f70afcb1f6779 101 Gene3D G3DSA:4.10.830.10 41 101 7.3E-30 T 06-07-2017 CAK95_RS21330 43a20b8e8acd46e1b70f70afcb1f6779 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 9.2E-25 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21330 43a20b8e8acd46e1b70f70afcb1f6779 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.887 T 06-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.4E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 Pfam PF03466 LysR substrate binding domain 100 311 1.8E-19 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 SUPERFAMILY SSF53850 94 310 1.86E-33 T 06-07-2017 CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 Gene3D G3DSA:1.10.10.10 4 89 2.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 Gene3D G3DSA:3.40.190.10 94 193 1.6E-21 T 06-07-2017 CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 Gene3D G3DSA:3.40.190.10 194 282 5.1E-27 T 06-07-2017 CAK95_RS12905 441604275255e8c1b9c5a11bee730094 327 SUPERFAMILY SSF46785 8 89 8.16E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10310 d615cc2bad52109443ad12fbe79a0b50 232 Pfam PF00912 Transglycosylase 53 200 9.3E-42 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK95_RS10310 d615cc2bad52109443ad12fbe79a0b50 232 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 8 224 37.581 T 06-07-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CAK95_RS10310 d615cc2bad52109443ad12fbe79a0b50 232 SUPERFAMILY SSF53955 40 222 5.06E-49 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS10310 d615cc2bad52109443ad12fbe79a0b50 232 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 17 220 1.9E-57 T 06-07-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CAK95_RS10310 d615cc2bad52109443ad12fbe79a0b50 232 Gene3D G3DSA:1.10.3810.10 52 202 9.5E-48 T 06-07-2017 CAK95_RS17520 6e8bc1bc0285961998afff05ba34ab25 162 Gene3D G3DSA:3.10.180.10 2 131 3.0E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17520 6e8bc1bc0285961998afff05ba34ab25 162 SUPERFAMILY SSF54593 1 133 9.4E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS17520 6e8bc1bc0285961998afff05ba34ab25 162 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 131 4.9E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS06375 ad5cd598d83c4d9203fa690f28a8e341 474 Pfam PF03734 L,D-transpeptidase catalytic domain 103 211 2.5E-21 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS06375 ad5cd598d83c4d9203fa690f28a8e341 474 SUPERFAMILY SSF141523 101 211 2.49E-30 T 06-07-2017 CAK95_RS06375 ad5cd598d83c4d9203fa690f28a8e341 474 PIRSF PIRSF029342 65 474 8.5E-97 T 06-07-2017 IPR016915 Uncharacterised conserved protein UCP029342 CAK95_RS06375 ad5cd598d83c4d9203fa690f28a8e341 474 Gene3D G3DSA:2.40.440.10 97 211 5.3E-22 T 06-07-2017 CAK95_RS23410 1098a619c6a9a782b31065dc1828d382 135 Pfam PF03733 Inner membrane component domain 7 57 9.3E-18 T 06-07-2017 IPR005185 Inner membrane component domain CAK95_RS23410 1098a619c6a9a782b31065dc1828d382 135 Pfam PF03733 Inner membrane component domain 79 129 2.6E-19 T 06-07-2017 IPR005185 Inner membrane component domain CAK95_RS23410 1098a619c6a9a782b31065dc1828d382 135 PIRSF PIRSF028777 4 135 2.6E-45 T 06-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 CAK95_RS19655 c5d4e8b09751409fe29f4320af455636 468 Pfam PF02321 Outer membrane efflux protein 267 440 3.2E-11 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS19655 c5d4e8b09751409fe29f4320af455636 468 Pfam PF02321 Outer membrane efflux protein 66 237 1.7E-5 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAK95_RS19655 c5d4e8b09751409fe29f4320af455636 468 SUPERFAMILY SSF56954 3 24 1.96E-52 T 06-07-2017 CAK95_RS19655 c5d4e8b09751409fe29f4320af455636 468 SUPERFAMILY SSF56954 56 444 1.96E-52 T 06-07-2017 CAK95_RS19655 c5d4e8b09751409fe29f4320af455636 468 Gene3D G3DSA:1.20.1600.10 60 446 8.7E-33 T 06-07-2017 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 Pfam PF00919 Uncharacterized protein family UPF0004 6 109 2.2E-29 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 160 180 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 Pfam PF01938 TRAM domain 388 447 1.1E-8 T 06-07-2017 IPR002792 TRAM domain CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 445 6.6E-145 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 Pfam PF04055 Radical SAM superfamily 161 334 3.2E-31 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 447 8.5E-145 T 06-07-2017 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 SUPERFAMILY SSF102114 133 380 7.98E-60 T 06-07-2017 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 5 448 70.987 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 Gene3D G3DSA:3.80.30.20 155 385 4.3E-77 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS09225 0c891b4f095b1897b4fed1068ebd7356 466 SMART SM00729 156 376 2.8E-59 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS11775 2dfc7757080d0642d1a514aa38ff287f 87 Gene3D G3DSA:3.30.450.40 12 65 1.5E-9 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11775 2dfc7757080d0642d1a514aa38ff287f 87 Pfam PF01614 Bacterial transcriptional regulator 13 65 1.9E-4 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS11775 2dfc7757080d0642d1a514aa38ff287f 87 SUPERFAMILY SSF55781 14 61 4.97E-8 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS14345 ecaa005ef440e6373f5dd1387ea74b6f 467 Gene3D G3DSA:3.90.1300.10 4 457 5.3E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS14345 ecaa005ef440e6373f5dd1387ea74b6f 467 Pfam PF01425 Amidase 26 446 2.1E-96 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS14345 ecaa005ef440e6373f5dd1387ea74b6f 467 SUPERFAMILY SSF75304 7 456 2.49E-123 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS18825 57a8512744285366168fd109f3ac64ac 151 Gene3D G3DSA:1.10.1750.10 33 119 1.7E-21 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS18825 57a8512744285366168fd109f3ac64ac 151 SMART SM00760 29 98 2.8E-15 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS18825 57a8512744285366168fd109f3ac64ac 151 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 33 96 7.7E-16 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK95_RS18825 57a8512744285366168fd109f3ac64ac 151 SUPERFAMILY SSF48295 30 118 5.49E-20 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAK95_RS26860 e41736247680712be93184b19538621b 425 Pfam PF05045 Rhamnan synthesis protein F 100 282 1.8E-16 T 06-07-2017 IPR007739 Rhamnan synthesis F CAK95_RS25800 82eae593be12a8943b78fcb671557ec4 319 PIRSF PIRSF017082 1 318 1.3E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25800 82eae593be12a8943b78fcb671557ec4 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 314 4.5E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25800 82eae593be12a8943b78fcb671557ec4 319 SUPERFAMILY SSF53850 107 284 4.64E-13 T 06-07-2017 CAK95_RS02165 f3df7009a6a74d3a62744b495f0e03af 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 79 1.1E-5 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS02165 f3df7009a6a74d3a62744b495f0e03af 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 106 329 6.6E-21 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS28475 c28cb8c4c84dcb546255f3c3d2faa219 112 Pfam PF06823 Protein of unknown function (DUF1236) 53 112 2.4E-17 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS15560 4c3c97f3cdc56f89febdcfecdce5bed3 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 298 4.4E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS04905 a289bd5da1f089b9c0291e27c2259aef 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 7 148 2.9E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS04905 a289bd5da1f089b9c0291e27c2259aef 155 SUPERFAMILY SSF55298 6 154 3.61E-45 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS04905 a289bd5da1f089b9c0291e27c2259aef 155 Gene3D G3DSA:3.30.1330.40 5 154 5.7E-52 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS14880 915487820716bd2d6d3f6a4eb5536d22 708 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 17 204 1.1E-40 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS14880 915487820716bd2d6d3f6a4eb5536d22 708 SUPERFAMILY SSF53067 16 93 7.14E-5 T 06-07-2017 CAK95_RS14880 915487820716bd2d6d3f6a4eb5536d22 708 SUPERFAMILY SSF53067 283 337 7.14E-5 T 06-07-2017 CAK95_RS14880 915487820716bd2d6d3f6a4eb5536d22 708 Pfam PF01968 Hydantoinase/oxoprolinase 225 508 4.9E-86 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS04500 eee31f06484bcda047e294b9e96f556e 230 Pfam PF01048 Phosphorylase superfamily 51 162 7.1E-14 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS04500 eee31f06484bcda047e294b9e96f556e 230 SUPERFAMILY SSF53167 51 162 7.59E-22 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS04500 eee31f06484bcda047e294b9e96f556e 230 Gene3D G3DSA:3.40.50.1580 50 161 1.4E-18 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK95_RS04500 eee31f06484bcda047e294b9e96f556e 230 TIGRFAM TIGR03468 HpnG: hopanoid-associated phosphorylase 8 215 1.8E-65 T 06-07-2017 IPR017831 Hopanoid-associated phosphorylase HpnG CAK95_RS08215 b0fdfdcf1c6d5f35e1201b6a659b1b56 393 SUPERFAMILY SSF53383 15 389 2.18E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS08215 b0fdfdcf1c6d5f35e1201b6a659b1b56 393 Pfam PF00155 Aminotransferase class I and II 32 379 3.4E-57 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK95_RS08215 b0fdfdcf1c6d5f35e1201b6a659b1b56 393 Gene3D G3DSA:3.40.640.10 45 257 7.6E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS08215 b0fdfdcf1c6d5f35e1201b6a659b1b56 393 Gene3D G3DSA:3.90.1150.10 258 388 2.7E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS05820 4497388c6ee6366114828d3616a5aef8 264 Gene3D G3DSA:3.40.50.1110 64 230 1.5E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05820 4497388c6ee6366114828d3616a5aef8 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 79 215 4.6E-11 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05820 4497388c6ee6366114828d3616a5aef8 264 SUPERFAMILY SSF52266 64 221 3.16E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 Gene3D G3DSA:3.50.50.60 4 178 1.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 Gene3D G3DSA:3.50.50.60 271 348 1.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 SUPERFAMILY SSF54373 180 265 6.67E-6 T 06-07-2017 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 Pfam PF01494 FAD binding domain 4 339 1.1E-20 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 SUPERFAMILY SSF51905 271 366 1.73E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 SUPERFAMILY SSF51905 4 173 1.73E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.1E-15 T 06-07-2017 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 6.1E-15 T 06-07-2017 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 6.1E-15 T 06-07-2017 CAK95_RS01775 c4aa4661125c2f183ee9ee9269bc0ca1 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 6.1E-15 T 06-07-2017 CAK95_RS19060 3e201acedee0ab047ca02c725ca11d15 76 Pfam PF09550 Phage tail assembly chaperone protein, TAC 11 67 3.5E-22 T 06-07-2017 IPR019056 Phage tail assembly chaperone protein, TAC6 CAK95_RS19060 3e201acedee0ab047ca02c725ca11d15 76 TIGRFAM TIGR02216 phage_TIGR02216: phage conserved hypothetical protein 10 68 1.4E-21 T 06-07-2017 IPR011739 Gene transfer agent, rcc01693 CAK95_RS25975 ab4b6821e65a5f936bf067d06c7b17cb 345 Pfam PF07859 alpha/beta hydrolase fold 110 316 6.0E-56 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS25975 ab4b6821e65a5f936bf067d06c7b17cb 345 Gene3D G3DSA:3.40.50.1820 65 340 1.1E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25975 ab4b6821e65a5f936bf067d06c7b17cb 345 SUPERFAMILY SSF53474 75 339 3.12E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS00360 e587afcacc27e3054b088e164f298fda 311 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 305 1.2E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00360 e587afcacc27e3054b088e164f298fda 311 SUPERFAMILY SSF56529 73 306 2.09E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00360 e587afcacc27e3054b088e164f298fda 311 Gene3D G3DSA:3.90.850.10 76 308 8.4E-74 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 94 1.1E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 Gene3D G3DSA:3.40.50.720 153 267 4.8E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 Gene3D G3DSA:3.90.180.10 6 152 1.9E-50 T 06-07-2017 IPR011032 GroES-like CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 SMART SM00829 17 330 1.5E-60 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 SUPERFAMILY SSF50129 4 152 1.11E-39 T 06-07-2017 IPR011032 GroES-like CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 SUPERFAMILY SSF51735 119 294 5.63E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 8 331 7.0E-126 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAK95_RS16850 caf74cf2add413cd190c8411c3d6a1c7 332 Pfam PF00107 Zinc-binding dehydrogenase 158 272 1.2E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 343 358 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 SUPERFAMILY SSF52833 47 207 5.81E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 Pfam PF10531 SLBB domain 419 468 3.1E-8 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 54 191 4.8E-27 T 06-07-2017 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 SUPERFAMILY SSF142019 202 415 4.05E-68 T 06-07-2017 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 233 394 3.5E-43 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 518 529 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 SUPERFAMILY SSF140490 502 586 7.72E-26 T 06-07-2017 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 SMART SM00928 505 550 6.7E-16 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 SUPERFAMILY SSF142984 417 500 4.71E-20 T 06-07-2017 CAK95_RS12780 2278a2314517c1823d66af241cec6c46 588 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 507 582 3.2E-22 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS12255 1c59e74d0d8d921fcc0091354f25b6d0 152 Gene3D G3DSA:3.10.129.10 3 139 6.0E-8 T 06-07-2017 IPR029069 HotDog domain CAK95_RS12255 1c59e74d0d8d921fcc0091354f25b6d0 152 SUPERFAMILY SSF54637 3 139 1.9E-11 T 06-07-2017 IPR029069 HotDog domain CAK95_RS06275 30316ad39acbae9092b3e7babf24a400 277 Gene3D G3DSA:1.10.3720.10 68 256 4.6E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06275 30316ad39acbae9092b3e7babf24a400 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 252 1.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06275 30316ad39acbae9092b3e7babf24a400 277 SUPERFAMILY SSF161098 71 257 3.01E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00750 ac75f08fd2d64de7130d36f33aaf1885 297 Gene3D G3DSA:3.40.50.10490 2 244 5.5E-68 T 06-07-2017 CAK95_RS00750 ac75f08fd2d64de7130d36f33aaf1885 297 SUPERFAMILY SSF53697 2 243 1.11E-59 T 06-07-2017 CAK95_RS00750 ac75f08fd2d64de7130d36f33aaf1885 297 Pfam PF13580 SIS domain 41 160 2.4E-7 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK95_RS00750 ac75f08fd2d64de7130d36f33aaf1885 297 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 289 33.222 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 SUPERFAMILY SSF47203 236 387 2.9E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 2.0E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 4.0E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Gene3D G3DSA:1.20.140.10 225 388 5.1E-66 T 06-07-2017 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 SUPERFAMILY SSF56645 8 250 1.83E-83 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Gene3D G3DSA:1.10.540.10 6 127 6.4E-43 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Gene3D G3DSA:2.40.110.10 129 224 6.6E-39 T 06-07-2017 CAK95_RS21735 93a6875be4a41abd37f36a93cecd0bb5 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 9.8E-37 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 SMART SM00922 142 251 1.6E-20 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 Gene3D G3DSA:3.30.390.10 1 126 3.0E-43 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 Pfam PF13378 Enolase C-terminal domain-like 145 366 1.8E-51 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 123 4.4E-18 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 SUPERFAMILY SSF54826 1 127 5.01E-32 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 Gene3D G3DSA:3.20.20.120 127 371 3.2E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 98 123 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAK95_RS24130 fd0808c85e7aca57e77a53ec3bc0477a 383 SUPERFAMILY SSF51604 111 370 9.69E-65 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS16760 1cd684d80e1967a836a1a70c59ab1563 399 Pfam PF13520 Amino acid permease 24 392 2.8E-35 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS16760 1cd684d80e1967a836a1a70c59ab1563 399 PIRSF PIRSF006060 4 399 6.7E-65 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS25570 ad391d463c6ddf2b2e6c9e05b9adbd53 154 SUPERFAMILY SSF55811 4 150 2.84E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS25570 ad391d463c6ddf2b2e6c9e05b9adbd53 154 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS25570 ad391d463c6ddf2b2e6c9e05b9adbd53 154 Gene3D G3DSA:3.90.79.10 3 149 2.6E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS25570 ad391d463c6ddf2b2e6c9e05b9adbd53 154 Pfam PF00293 NUDIX domain 3 146 2.6E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 Pfam PF00106 short chain dehydrogenase 8 201 1.3E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 Gene3D G3DSA:3.40.50.720 6 246 1.1E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS28805 864c74e35f2cc5bf7fc07754ef4e9885 280 SUPERFAMILY SSF51735 5 214 6.52E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS18150 ac6bcef743e1bac082b935b29196338c 598 Pfam PF00700 Bacterial flagellin C-terminal helical region 514 598 2.7E-8 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS18150 ac6bcef743e1bac082b935b29196338c 598 Pfam PF00669 Bacterial flagellin N-terminal helical region 13 104 5.1E-10 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS18150 ac6bcef743e1bac082b935b29196338c 598 SUPERFAMILY SSF64518 293 598 1.7E-26 T 06-07-2017 CAK95_RS18150 ac6bcef743e1bac082b935b29196338c 598 Gene3D G3DSA:1.20.1330.10 432 552 2.8E-12 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAK95_RS18150 ac6bcef743e1bac082b935b29196338c 598 SUPERFAMILY SSF64518 1 296 1.57E-21 T 06-07-2017 CAK95_RS10080 a1c889858a1cb6b73b868bafaa44eaa4 342 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 4 265 1.5E-69 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10080 a1c889858a1cb6b73b868bafaa44eaa4 342 Gene3D G3DSA:3.30.365.10 6 150 1.4E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10080 a1c889858a1cb6b73b868bafaa44eaa4 342 SUPERFAMILY SSF56003 4 327 2.09E-93 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS10080 a1c889858a1cb6b73b868bafaa44eaa4 342 Gene3D G3DSA:3.30.365.10 151 328 8.7E-58 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 Pfam PF01565 FAD binding domain 4 145 6.6E-18 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 SUPERFAMILY SSF56176 4 183 2.1E-31 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 Pfam PF02913 FAD linked oxidases, C-terminal domain 375 399 1.5E-4 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 Gene3D G3DSA:3.30.43.10 5 61 8.2E-4 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 Gene3D G3DSA:1.10.45.10 379 400 1.4E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 SUPERFAMILY SSF55103 197 401 1.96E-24 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK95_RS13045 ecdd5ee452e86dad0af847cd98b81494 404 Gene3D G3DSA:3.30.465.10 62 183 5.8E-16 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS11190 1151dbe391e891f123f82dff0f08124b 511 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 217 2.4E-22 T 06-07-2017 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 1.9E-27 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 1.9E-27 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.9E-27 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 PRINTS PR01798 Succinyl-CoA synthase signature 80 97 1.9E-27 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 SMART SM00881 2 98 7.9E-24 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 SUPERFAMILY SSF51735 3 120 3.03E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 Gene3D G3DSA:3.40.50.261 118 286 3.7E-57 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 Pfam PF02629 CoA binding domain 5 97 2.0E-21 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 PIRSF PIRSF001553 1 291 3.0E-104 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 281 1.1E-16 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 SUPERFAMILY SSF52210 121 286 4.32E-44 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK95_RS09395 b909d0da584c6db967584842a49675b5 296 Gene3D G3DSA:3.40.50.720 2 117 4.7E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21590 a4451cc730521eb1907c66ff26cf5324 155 Gene3D G3DSA:3.10.50.40 33 154 8.3E-51 T 06-07-2017 CAK95_RS21590 a4451cc730521eb1907c66ff26cf5324 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 59 152 3.3E-36 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAK95_RS21590 a4451cc730521eb1907c66ff26cf5324 155 SUPERFAMILY SSF54534 39 155 1.14E-45 T 06-07-2017 CAK95_RS00590 6f357fee0e3018cc6a0c92f2ac7385bd 243 SUPERFAMILY SSF56925 39 235 4.71E-31 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS00590 6f357fee0e3018cc6a0c92f2ac7385bd 243 Gene3D G3DSA:2.40.160.20 32 241 1.8E-37 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS00590 6f357fee0e3018cc6a0c92f2ac7385bd 243 Pfam PF13505 Outer membrane protein beta-barrel domain 15 232 1.4E-21 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 Pfam PF00037 4Fe-4S binding domain 34 55 1.0E-6 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 Pfam PF11953 Domain of unknown function (DUF3470) 66 105 3.1E-17 T 06-07-2017 IPR022569 Ferredoxin, C-terminal CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.9E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.9E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.9E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 Pfam PF12800 4Fe-4S binding domain 7 23 0.47 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 SUPERFAMILY SSF54862 4 79 5.02E-21 T 06-07-2017 CAK95_RS03730 391fc58b07a044222466346b7cd82e64 114 Gene3D G3DSA:3.30.70.20 5 82 9.9E-19 T 06-07-2017 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 PIRSF PIRSF038971 6 385 1.2E-127 T 06-07-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 SUPERFAMILY SSF51556 212 352 9.07E-13 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 SUPERFAMILY SSF51556 57 184 9.07E-13 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 9 384 1.5E-144 T 06-07-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 Gene3D G3DSA:2.30.40.10 263 366 7.7E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 Gene3D G3DSA:2.30.40.10 9 58 2.3E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 SUPERFAMILY SSF51338 352 384 5.34E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 SUPERFAMILY SSF51338 9 57 5.34E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS27895 b22768685dff129c5dea8af0b3d2d703 385 Pfam PF01979 Amidohydrolase family 54 382 2.0E-7 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS05375 b157b9ada6b3eb7b742b9ed12031299d 312 Gene3D G3DSA:1.20.1510.10 23 237 2.2E-49 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK95_RS05375 b157b9ada6b3eb7b742b9ed12031299d 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 311 6.7E-68 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS05375 b157b9ada6b3eb7b742b9ed12031299d 312 Pfam PF01545 Cation efflux family 28 237 2.8E-34 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS05375 b157b9ada6b3eb7b742b9ed12031299d 312 SUPERFAMILY SSF161111 20 238 8.24E-48 T 06-07-2017 CAK95_RS08360 a9d61f9b0fcafb0553aaddd78857a0db 238 SUPERFAMILY SSF52317 1 188 9.72E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS08360 a9d61f9b0fcafb0553aaddd78857a0db 238 Pfam PF00117 Glutamine amidotransferase class-I 46 179 5.5E-15 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK95_RS08360 a9d61f9b0fcafb0553aaddd78857a0db 238 Gene3D G3DSA:3.40.50.880 3 226 1.3E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 5.7E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 235 259 5.7E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 327 346 5.7E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 5.7E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 5.7E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS06455 83e528c7d090d5e15d70c3fa87f91568 507 Pfam PF00361 Proton-conducting membrane transporter 127 411 2.4E-39 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 SUPERFAMILY SSF51905 4 288 4.7E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 SUPERFAMILY SSF51905 472 532 4.7E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 SUPERFAMILY SSF54373 290 473 7.55E-48 T 06-07-2017 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 Gene3D G3DSA:3.50.50.60 187 313 1.6E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 Gene3D G3DSA:3.50.50.60 3 126 1.6E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 Gene3D G3DSA:3.50.50.60 466 531 1.6E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 Pfam PF05199 GMC oxidoreductase 387 522 1.5E-42 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 Pfam PF00732 GMC oxidoreductase 7 295 4.1E-82 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11485 e22c48217ffdefac4033270db272799f 533 PIRSF PIRSF000137 1 533 8.8E-152 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK95_RS19085 5090f4ab1046cf3fe73478d6899e6487 155 TIGRFAM TIGR02219 phage_NlpC_fam: putative phage cell wall peptidase, NlpC/P60 family 8 141 2.6E-61 T 06-07-2017 IPR011929 NlpC/P60 family, putative phage cell wall peptidase CAK95_RS19085 5090f4ab1046cf3fe73478d6899e6487 155 SUPERFAMILY SSF54001 4 142 1.18E-20 T 06-07-2017 CAK95_RS19085 5090f4ab1046cf3fe73478d6899e6487 155 Pfam PF00877 NlpC/P60 family 17 133 2.6E-9 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS19085 5090f4ab1046cf3fe73478d6899e6487 155 Gene3D G3DSA:3.90.1720.10 6 145 3.5E-30 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 Gene3D G3DSA:1.20.5.100 240 275 5.9E-19 T 06-07-2017 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 239 254 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 52 71 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 133 157 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 200 219 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 32 51 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 100 120 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 220 239 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 PRINTS PR00603 Cytochrome C1 signature 189 200 2.5E-66 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 Gene3D G3DSA:1.10.760.10 25 239 1.9E-80 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 SUPERFAMILY SSF81496 239 275 1.7E-6 T 06-07-2017 IPR021157 Cytochrome c1, transmembrane anchor, C-terminal Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 Pfam PF02167 Cytochrome C1 family 34 272 3.3E-98 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAK95_RS00555 e8eb1e4196b9a239c19fe12e8ae11bff 293 SUPERFAMILY SSF46626 28 238 1.77E-64 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS15900 68ebb48edf0d8f7a30cfc476c6397e12 278 SUPERFAMILY SSF53300 39 244 2.43E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS15900 68ebb48edf0d8f7a30cfc476c6397e12 278 Gene3D G3DSA:3.40.50.410 42 191 2.5E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS15900 68ebb48edf0d8f7a30cfc476c6397e12 278 Pfam PF06707 Protein of unknown function (DUF1194) 41 246 4.4E-77 T 06-07-2017 IPR010607 Protein of unknown function DUF1194 CAK95_RS07315 d4c8fe78472c538c7a5571a1dedadad8 229 PIRSF PIRSF026671 10 229 6.3E-65 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAK95_RS07315 d4c8fe78472c538c7a5571a1dedadad8 229 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 33 227 30.871 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAK95_RS07315 d4c8fe78472c538c7a5571a1dedadad8 229 SUPERFAMILY SSF55166 31 228 1.18E-58 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS07315 d4c8fe78472c538c7a5571a1dedadad8 229 Pfam PF01427 D-ala-D-ala dipeptidase 33 228 2.0E-38 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAK95_RS07315 d4c8fe78472c538c7a5571a1dedadad8 229 Gene3D G3DSA:3.30.1380.10 32 228 3.7E-67 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS05810 9835bfd04e5bc82d179fead671a33813 369 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 10 367 9.1E-173 T 06-07-2017 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAK95_RS05810 9835bfd04e5bc82d179fead671a33813 369 SUPERFAMILY SSF51283 12 173 3.14E-29 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS05810 9835bfd04e5bc82d179fead671a33813 369 Gene3D G3DSA:2.70.40.10 174 344 9.0E-63 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS05810 9835bfd04e5bc82d179fead671a33813 369 Gene3D G3DSA:2.70.40.10 11 172 2.0E-58 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS05810 9835bfd04e5bc82d179fead671a33813 369 SUPERFAMILY SSF51283 202 343 3.66E-21 T 06-07-2017 IPR029054 dUTPase-like CAK95_RS10845 7ec96c085f56360bf611e3b52f814b4d 111 SUPERFAMILY SSF54909 1 103 4.98E-34 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS10845 7ec96c085f56360bf611e3b52f814b4d 111 Gene3D G3DSA:3.30.70.900 1 102 5.5E-35 T 06-07-2017 CAK95_RS10845 7ec96c085f56360bf611e3b52f814b4d 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 5.3E-20 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAK95_RS05805 77bac8a7b9997efe2f81611df1337128 324 Gene3D G3DSA:3.40.190.10 128 213 1.4E-8 T 06-07-2017 CAK95_RS05805 77bac8a7b9997efe2f81611df1337128 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.7E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05805 77bac8a7b9997efe2f81611df1337128 324 SUPERFAMILY SSF53850 114 260 1.85E-16 T 06-07-2017 CAK95_RS05805 77bac8a7b9997efe2f81611df1337128 324 PIRSF PIRSF017082 5 323 3.0E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00630 761aeedb48ed71fdf3bb40824a6f240a 688 SUPERFAMILY SSF52317 259 510 4.81E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS00630 761aeedb48ed71fdf3bb40824a6f240a 688 Gene3D G3DSA:3.40.50.880 255 511 7.8E-32 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 1 128 1.1E-33 T 06-07-2017 IPR011855 Phage major tail protein TP901-1 CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 Pfam PF06199 Phage tail tube protein 3 132 2.7E-45 T 06-07-2017 IPR011855 Phage major tail protein TP901-1 CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 PRINTS PR01996 Phage major tail protein 1 family signature 81 104 1.4E-49 T 06-07-2017 IPR022344 Gene transfer agent, major tail protein CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 PRINTS PR01996 Phage major tail protein 1 family signature 1 13 1.4E-49 T 06-07-2017 IPR022344 Gene transfer agent, major tail protein CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 PRINTS PR01996 Phage major tail protein 1 family signature 108 132 1.4E-49 T 06-07-2017 IPR022344 Gene transfer agent, major tail protein CAK95_RS19050 b8b6396f267ae252ea170995742e4224 135 PRINTS PR01996 Phage major tail protein 1 family signature 19 48 1.4E-49 T 06-07-2017 IPR022344 Gene transfer agent, major tail protein CAK95_RS11970 1aec2f269d6ab2327c345fe72687b98a 172 SUPERFAMILY SSF46785 5 132 6.39E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11970 1aec2f269d6ab2327c345fe72687b98a 172 Gene3D G3DSA:1.10.10.10 3 105 4.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS11970 1aec2f269d6ab2327c345fe72687b98a 172 Pfam PF01638 HxlR-like helix-turn-helix 17 106 9.1E-19 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS17975 5aad3f62de1d79a3ecd9ad26c21edf3e 118 Gene3D G3DSA:1.20.120.160 4 115 2.5E-23 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS17975 5aad3f62de1d79a3ecd9ad26c21edf3e 118 SUPERFAMILY SSF47226 12 107 1.96E-16 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS17975 5aad3f62de1d79a3ecd9ad26c21edf3e 118 Pfam PF01627 Hpt domain 50 106 6.0E-7 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 Gene3D G3DSA:3.10.180.10 11 128 8.0E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 Gene3D G3DSA:3.10.180.10 162 281 2.5E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 SUPERFAMILY SSF54593 6 130 9.4E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 SUPERFAMILY SSF54593 162 277 7.25E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 163 275 3.9E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS27330 7f881156f57dd4b3f3214df1750cf908 302 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 127 1.2E-12 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS21755 d23d951e3d5de866960d72fce40d5396 115 Pfam PF13560 Helix-turn-helix domain 55 93 1.1E-7 T 06-07-2017 CAK95_RS21755 d23d951e3d5de866960d72fce40d5396 115 SMART SM00530 53 111 8.7E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS21755 d23d951e3d5de866960d72fce40d5396 115 SUPERFAMILY SSF47413 55 101 7.88E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS21755 d23d951e3d5de866960d72fce40d5396 115 Gene3D G3DSA:1.10.260.40 55 105 5.5E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 Gene3D G3DSA:3.20.20.120 126 347 6.0E-49 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 Pfam PF13378 Enolase C-terminal domain-like 142 351 1.4E-35 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 186 217 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 SUPERFAMILY SSF54826 1 124 4.66E-23 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 SUPERFAMILY SSF51604 134 359 4.35E-45 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 SMART SM00922 139 236 9.1E-23 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 Gene3D G3DSA:3.30.390.10 1 125 4.5E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK95_RS07200 0469dec7e2bd6871eebab43d2533cd1b 363 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 123 1.4E-8 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAK95_RS16070 39baa5dee412dab483e3513b10d1cbd4 97 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 31 95 9.8E-14 T 06-07-2017 IPR008792 Coenzyme PQQ synthesis D CAK95_RS16070 39baa5dee412dab483e3513b10d1cbd4 97 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 15 96 6.3E-25 T 06-07-2017 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 Gene3D G3DSA:3.30.565.10 225 344 3.0E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 Gene3D G3DSA:3.30.450.20 17 132 5.2E-8 T 06-07-2017 CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 Pfam PF13581 Histidine kinase-like ATPase domain 248 343 4.4E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 SUPERFAMILY SSF55874 247 346 5.5E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 Pfam PF00989 PAS fold 21 131 2.2E-5 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 SUPERFAMILY SSF55785 11 132 1.58E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 SMART SM00387 250 349 8.3E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS14390 c0fee661d31f12bb20f6017b4b2d726e 363 Pfam PF07568 Histidine kinase 154 228 7.7E-20 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CAK95_RS22780 c740c79575dade0b7c661d33bdebeafb 128 Pfam PF03815 LCCL domain 58 118 2.7E-11 T 06-07-2017 IPR004043 LCCL domain CAK95_RS22780 c740c79575dade0b7c661d33bdebeafb 128 SUPERFAMILY SSF69848 59 125 9.15E-13 T 06-07-2017 IPR004043 LCCL domain CAK95_RS22780 c740c79575dade0b7c661d33bdebeafb 128 Gene3D G3DSA:2.170.130.20 58 125 3.8E-12 T 06-07-2017 IPR004043 LCCL domain CAK95_RS18495 bbdb2ca7e09db02578cf3e178170bfea 96 Pfam PF10048 Predicted integral membrane protein (DUF2282) 36 90 3.6E-25 T 06-07-2017 IPR018740 Protein of unknown function DUF2282, integral membrane CAK95_RS14990 d8cccdd30808f2dcd3682c23c07ad96d 279 SUPERFAMILY SSF46626 47 166 3.72E-30 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14990 d8cccdd30808f2dcd3682c23c07ad96d 279 SUPERFAMILY SSF46626 170 279 1.79E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14990 d8cccdd30808f2dcd3682c23c07ad96d 279 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 71 278 5.3E-70 T 06-07-2017 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 CAK95_RS14990 d8cccdd30808f2dcd3682c23c07ad96d 279 Gene3D G3DSA:1.10.760.10 104 278 5.9E-50 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS14990 d8cccdd30808f2dcd3682c23c07ad96d 279 PIRSF PIRSF038455 17 279 2.7E-80 T 06-07-2017 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 CAK95_RS01965 90d504b4940f6ef6c17de44dd5fe229e 82 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 6 64 2.0E-5 T 06-07-2017 IPR018691 Protein of unknown function DUF2188 CAK95_RS09485 a37d33a2dab3db8518de63fd2447276a 165 Pfam PF03928 Haem-degrading 33 157 2.9E-31 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS09485 a37d33a2dab3db8518de63fd2447276a 165 SUPERFAMILY SSF143744 32 161 2.48E-36 T 06-07-2017 CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 Pfam PF12840 Helix-turn-helix domain 5 62 7.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 SMART SM00418 5 83 3.8E-23 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 Gene3D G3DSA:1.10.10.10 6 97 4.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 2.6E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.6E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 2.6E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS09715 cd597ec935fc24808667a3ff08eb0a1f 102 SUPERFAMILY SSF46785 4 97 1.45E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28925 8d885170b4a8089a8bc9551647d15350 253 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 5 76 1.2E-29 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family CAK95_RS28925 8d885170b4a8089a8bc9551647d15350 253 Pfam PF13586 Transposase DDE domain 163 246 1.7E-23 T 06-07-2017 IPR025668 Transposase DDE domain CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 8.8E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 9 24 8.8E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 8.8E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 Gene3D G3DSA:1.10.10.10 5 106 9.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 SMART SM00418 7 82 6.7E-20 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 SUPERFAMILY SSF46785 5 98 4.37E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25105 d8bb299b4307808a85b159ad2675f829 107 Pfam PF12840 Helix-turn-helix domain 8 66 7.0E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28685 1a42c44f296a894f46e277ac6a737e2e 176 Gene3D G3DSA:3.10.180.10 4 162 2.9E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28685 1a42c44f296a894f46e277ac6a737e2e 176 SUPERFAMILY SSF54593 6 159 8.99E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28685 1a42c44f296a894f46e277ac6a737e2e 176 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 141 2.4E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 SUPERFAMILY SSF56300 39 62 2.92E-79 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 SUPERFAMILY SSF56300 116 374 2.92E-79 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 3 560 4.0E-258 T 06-07-2017 IPR030998 Thiosulfohydrolase SoxB CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 SUPERFAMILY SSF55816 373 559 5.1E-37 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 Gene3D G3DSA:3.60.21.10 116 373 8.1E-79 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 Gene3D G3DSA:3.60.21.10 42 62 8.1E-79 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 Pfam PF02872 5'-nucleotidase, C-terminal domain 391 521 6.5E-19 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 Gene3D G3DSA:3.90.780.10 377 558 1.3E-22 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 PRINTS PR01607 Apyrase family signature 313 333 1.1E-12 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 PRINTS PR01607 Apyrase family signature 509 528 1.1E-12 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 PRINTS PR01607 Apyrase family signature 285 308 1.1E-12 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 PRINTS PR01607 Apyrase family signature 43 61 1.1E-12 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS23465 4645cce3659027f04d7d520c439ed6e0 560 PRINTS PR01607 Apyrase family signature 266 283 1.1E-12 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAK95_RS13605 1f438d2b17f004c1635873215a4cf7e7 298 SMART SM00382 43 229 1.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13605 1f438d2b17f004c1635873215a4cf7e7 298 Pfam PF00005 ABC transporter 35 181 1.7E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13605 1f438d2b17f004c1635873215a4cf7e7 298 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS13605 1f438d2b17f004c1635873215a4cf7e7 298 Gene3D G3DSA:3.40.50.300 16 248 1.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13605 1f438d2b17f004c1635873215a4cf7e7 298 SUPERFAMILY SSF52540 14 244 3.07E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22810 a56d707bab1c0b02a74abb76f9f3a516 486 Pfam PF04317 YcjX-like family, DUF463 31 485 1.0E-164 T 06-07-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein CAK95_RS22810 a56d707bab1c0b02a74abb76f9f3a516 486 PIRSF PIRSF019381 2 486 4.1E-167 T 06-07-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein CAK95_RS00665 a1b8f59bab7949ff8898500ca7bdf46b 415 Pfam PF01425 Amidase 37 193 8.6E-47 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS00665 a1b8f59bab7949ff8898500ca7bdf46b 415 Pfam PF01425 Amidase 300 401 2.3E-7 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS00665 a1b8f59bab7949ff8898500ca7bdf46b 415 Gene3D G3DSA:3.90.1300.10 32 411 4.2E-88 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS00665 a1b8f59bab7949ff8898500ca7bdf46b 415 SUPERFAMILY SSF75304 18 412 3.14E-87 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS16645 5cf6734f19e3b703b58eada7cb0c3e47 171 SUPERFAMILY SSF54593 5 133 6.33E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS16645 5cf6734f19e3b703b58eada7cb0c3e47 171 Gene3D G3DSA:3.10.180.10 10 130 1.2E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 262 278 2.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 248 262 2.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 278 290 2.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 Gene3D G3DSA:1.10.10.10 248 304 6.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 SUPERFAMILY SSF46894 240 304 6.12E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 SMART SM00421 245 302 3.1E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 Pfam PF00196 Bacterial regulatory proteins, luxR family 248 302 5.6E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 SUPERFAMILY SSF52172 10 141 9.68E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 Pfam PF00072 Response regulator receiver domain 10 122 5.5E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 SMART SM00448 8 121 4.1E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS28525 38617e23b5b0f5b7a222f8a27ecef8d8 309 Gene3D G3DSA:3.40.50.2300 9 133 1.1E-39 T 06-07-2017 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 Gene3D G3DSA:1.10.10.10 25 158 1.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 77 96 3.6E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 66 77 3.6E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 SMART SM00347 43 144 3.7E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 SUPERFAMILY SSF46785 20 160 3.91E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 Pfam PF01047 MarR family 58 107 5.7E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 8.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 8.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS07175 ff70ac5bc82bb82ec9f93dce4c5cf6c8 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 8.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS26400 de51eee82ff2996a86f58faa18e7b38b 63 Pfam PF10931 Protein of unknown function (DUF2735) 9 58 1.8E-13 T 06-07-2017 IPR021232 Protein of unknown function DUF2735 CAK95_RS18465 42e73c6e6e3849dcdde4b317ec214878 190 SUPERFAMILY SSF50475 26 176 1.18E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS18465 42e73c6e6e3849dcdde4b317ec214878 190 SMART SM00903 31 177 5.6E-41 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS18465 42e73c6e6e3849dcdde4b317ec214878 190 Pfam PF01613 Flavin reductase like domain 31 176 5.9E-28 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS18465 42e73c6e6e3849dcdde4b317ec214878 190 Gene3D G3DSA:2.30.110.10 20 175 1.9E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS11015 4b87aa127611908a0e953175ab4154f7 1041 Pfam PF12705 PD-(D/E)XK nuclease superfamily 762 993 9.1E-21 T 06-07-2017 CAK95_RS11015 4b87aa127611908a0e953175ab4154f7 1041 SUPERFAMILY SSF52540 353 714 1.38E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11015 4b87aa127611908a0e953175ab4154f7 1041 Gene3D G3DSA:3.40.50.300 351 432 3.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11015 4b87aa127611908a0e953175ab4154f7 1041 Gene3D G3DSA:3.40.50.300 619 653 3.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11015 4b87aa127611908a0e953175ab4154f7 1041 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 7 1030 0.0 T 06-07-2017 IPR014153 Double-strand break repair protein AddB CAK95_RS28210 d92fb97679344074bc3ae907a6617bef 396 PIRSF PIRSF000138 1 381 4.1E-129 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAK95_RS28210 d92fb97679344074bc3ae907a6617bef 396 Gene3D G3DSA:3.20.20.70 4 380 4.4E-142 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS28210 d92fb97679344074bc3ae907a6617bef 396 SUPERFAMILY SSF51395 4 376 4.7E-103 T 06-07-2017 CAK95_RS28210 d92fb97679344074bc3ae907a6617bef 396 Pfam PF01070 FMN-dependent dehydrogenase 14 377 3.2E-137 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK95_RS28210 d92fb97679344074bc3ae907a6617bef 396 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 274 280 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 Pfam PF01047 MarR family 32 89 1.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 SUPERFAMILY SSF46785 5 141 7.11E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 SMART SM00347 25 125 4.9E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 7 136 2.6E-44 T 06-07-2017 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 9.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 9.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28365 5cadb70296cbde7293e4c4277a0c55a6 163 Gene3D G3DSA:1.10.10.10 6 137 1.9E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS14380 7e42a3b3d7a45deb4fe679194b715501 246 Pfam PF06823 Protein of unknown function (DUF1236) 176 245 1.2E-18 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS06550 f8d13da96f8722e0d83cd3ad61dde159 74 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 06-07-2017 IPR001455 TusA-like domain CAK95_RS06550 f8d13da96f8722e0d83cd3ad61dde159 74 Gene3D G3DSA:3.30.110.40 2 73 3.8E-21 T 06-07-2017 IPR001455 TusA-like domain CAK95_RS06550 f8d13da96f8722e0d83cd3ad61dde159 74 SUPERFAMILY SSF64307 4 73 3.14E-20 T 06-07-2017 IPR001455 TusA-like domain CAK95_RS06550 f8d13da96f8722e0d83cd3ad61dde159 74 Pfam PF01206 Sulfurtransferase TusA 4 73 2.0E-17 T 06-07-2017 IPR001455 TusA-like domain CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 219 238 1.4E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 408 424 1.4E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 267 1.4E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 SUPERFAMILY SSF52743 202 470 5.5E-74 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 224 235 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 Gene3D G3DSA:3.40.50.200 171 468 2.8E-78 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 258 268 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAK95_RS18630 e0047799885f06528eb6dd7520ffe8b6 485 Pfam PF00082 Subtilase family 219 459 3.2E-44 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK95_RS21685 cb1220f6538cdffe9e0a4764aba6b244 431 Pfam PF02308 MgtC family 11 142 1.7E-18 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK95_RS21685 cb1220f6538cdffe9e0a4764aba6b244 431 Pfam PF13194 Domain of unknown function (DUF4010) 190 399 2.1E-52 T 06-07-2017 IPR025105 Domain of unknown function DUF4010 CAK95_RS07330 50c11b66516cf6c1c110d0c562077781 155 SUPERFAMILY SSF81301 42 146 5.23E-36 T 06-07-2017 CAK95_RS07330 50c11b66516cf6c1c110d0c562077781 155 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 46 143 7.1E-34 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAK95_RS07330 50c11b66516cf6c1c110d0c562077781 155 Pfam PF02410 Ribosomal silencing factor during starvation 49 143 2.2E-24 T 06-07-2017 CAK95_RS07330 50c11b66516cf6c1c110d0c562077781 155 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 42 144 24.464 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAK95_RS07330 50c11b66516cf6c1c110d0c562077781 155 Gene3D G3DSA:3.30.460.10 42 145 6.0E-35 T 06-07-2017 CAK95_RS05940 a6dcc7b83b438436a304ff42888386f5 343 SUPERFAMILY SSF51726 9 329 6.8E-52 T 06-07-2017 CAK95_RS05940 a6dcc7b83b438436a304ff42888386f5 343 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 26 326 8.5E-25 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS05940 a6dcc7b83b438436a304ff42888386f5 343 Gene3D G3DSA:3.20.20.210 3 329 2.6E-60 T 06-07-2017 CAK95_RS27110 79b52b9398c84e443e68b4dc43960069 348 SUPERFAMILY SSF144052 22 280 1.16E-13 T 06-07-2017 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 Gene3D G3DSA:2.130.10.10 142 338 2.5E-21 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SMART SM00320 298 338 6.1 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SMART SM00320 256 295 13.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SMART SM00320 52 89 20.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SMART SM00320 210 248 1.2 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SMART SM00320 130 167 360.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 Gene3D G3DSA:2.120.10.30 42 132 9.6E-9 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 SUPERFAMILY SSF50998 65 331 3.06E-31 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAK95_RS12900 c2c7d14a5f245d8ae507ca426dd2fe5f 340 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 277 332 2.2E-4 T 06-07-2017 IPR024977 Anaphase-promoting complex subunit 4, WD40 domain CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 Gene3D G3DSA:1.10.10.10 152 251 8.0E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 Gene3D G3DSA:3.40.50.2300 26 151 1.7E-34 T 06-07-2017 CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 176 249 1.5E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 SUPERFAMILY SSF52172 29 209 3.18E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 SMART SM00862 174 250 1.1E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 SMART SM00448 30 141 4.3E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS19185 32ee4a37dd024554bec3d80eebffd03d 255 Pfam PF00072 Response regulator receiver domain 33 141 3.2E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 Pfam PF01494 FAD binding domain 4 356 1.1E-72 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 SUPERFAMILY SSF51905 4 192 1.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 SUPERFAMILY SSF51905 280 364 1.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 Gene3D G3DSA:3.50.50.60 116 197 4.0E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 Gene3D G3DSA:3.50.50.60 4 72 4.0E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 Gene3D G3DSA:3.50.50.60 281 359 4.0E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 8.4E-39 T 06-07-2017 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 8.4E-39 T 06-07-2017 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 8.4E-39 T 06-07-2017 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.4E-39 T 06-07-2017 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 8.4E-39 T 06-07-2017 CAK95_RS19270 fcd154c6b0557ea48fd25cd473435dda 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 8.4E-39 T 06-07-2017 CAK95_RS08185 2c2feedab2230d489b31760c0367a011 599 SUPERFAMILY SSF52540 275 509 2.77E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08185 2c2feedab2230d489b31760c0367a011 599 SUPERFAMILY SSF52540 130 230 2.77E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08185 2c2feedab2230d489b31760c0367a011 599 Gene3D G3DSA:3.40.50.300 340 505 1.4E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08185 2c2feedab2230d489b31760c0367a011 599 Gene3D G3DSA:3.40.50.300 144 217 1.4E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08185 2c2feedab2230d489b31760c0367a011 599 Pfam PF01935 Domain of unknown function DUF87 132 378 5.0E-44 T 06-07-2017 IPR002789 Helicase HerA, central domain CAK95_RS25360 d241207649508577841057a8f0ec6279 136 Gene3D G3DSA:1.10.10.10 11 119 5.5E-45 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25360 d241207649508577841057a8f0ec6279 136 Pfam PF01638 HxlR-like helix-turn-helix 22 107 6.3E-29 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS25360 d241207649508577841057a8f0ec6279 136 SUPERFAMILY SSF46785 10 120 7.18E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13770 3f386177a0cb29496e6e8b3301f1ccb2 161 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 22 151 2.3E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS15325 b4eb16fda962d98ac0b2b61c8947410c 113 Pfam PF06108 Protein of unknown function (DUF952) 7 94 2.8E-32 T 06-07-2017 IPR009297 Protein of unknown function DUF952 CAK95_RS15325 b4eb16fda962d98ac0b2b61c8947410c 113 SUPERFAMILY SSF56399 3 110 4.03E-40 T 06-07-2017 CAK95_RS18410 592f0ef34a48a8bd5d358d5305ecb236 210 Pfam PF11454 Protein of unknown function (DUF3016) 71 206 3.0E-35 T 06-07-2017 IPR021557 Protein of unknown function DUF3016 CAK95_RS19215 4e28eee6785babd0ef90dbea81b89f4f 208 Pfam PF16357 Putative PepSY_TM-like 12 208 3.1E-77 T 06-07-2017 IPR032307 Putative PepSY TM-like protein CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 Gene3D G3DSA:3.40.190.10 187 265 3.8E-16 T 06-07-2017 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 Gene3D G3DSA:3.40.190.10 94 186 3.2E-14 T 06-07-2017 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 SUPERFAMILY SSF46785 6 116 1.72E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 9.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 9.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 9.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 Gene3D G3DSA:1.10.10.10 9 90 8.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 SUPERFAMILY SSF53850 95 302 2.65E-31 T 06-07-2017 CAK95_RS04800 53e4d3be4912cb849be6fdb2b92b0c4b 311 Pfam PF03466 LysR substrate binding domain 94 298 1.1E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS28450 05dbedab74f0cbcc10a08eb9c55ca396 120 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 5 91 3.7E-33 T 06-07-2017 IPR014057 Addiction module antidote protein, HI1420 CAK95_RS28450 05dbedab74f0cbcc10a08eb9c55ca396 120 Gene3D G3DSA:1.10.260.40 50 89 3.8E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS28450 05dbedab74f0cbcc10a08eb9c55ca396 120 SUPERFAMILY SSF47413 30 89 1.13E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS19320 64c52795f066f979a4d8a6ffcf07bd5f 286 Pfam PF13468 Glyoxalase-like domain 8 190 2.8E-16 T 06-07-2017 IPR025870 Glyoxalase-like domain CAK95_RS19320 64c52795f066f979a4d8a6ffcf07bd5f 286 SUPERFAMILY SSF54593 1 114 1.06E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS19320 64c52795f066f979a4d8a6ffcf07bd5f 286 Gene3D G3DSA:3.10.180.10 4 116 5.2E-4 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 SUPERFAMILY SSF51182 33 462 2.48E-168 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 Pfam PF04209 homogentisate 1,2-dioxygenase 33 457 2.3E-206 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 32 457 1.6E-203 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 Gene3D G3DSA:2.60.120.10 310 427 9.6E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 Gene3D G3DSA:2.60.120.10 230 249 9.6E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 Gene3D G3DSA:2.60.120.10 163 229 3.5E-5 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20005 80391559a04af2ea169b72dc727998b7 465 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 33 459 69.819 T 06-07-2017 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 246 5.7E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 Pfam PF00005 ABC transporter 22 176 4.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 SUPERFAMILY SSF52540 4 245 9.32E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 SMART SM00382 30 224 3.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 Gene3D G3DSA:3.40.50.300 4 244 7.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10000 bf63ec9b5fae522de9d3b7700895fc31 250 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS21925 c9417ddf08a90d7ab090797cd16ee7d6 242 SUPERFAMILY SSF53300 47 208 3.16E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS25520 6e386305a3dcb172f59dfef06a3d02b9 464 Pfam PF01425 Amidase 20 445 8.3E-87 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS25520 6e386305a3dcb172f59dfef06a3d02b9 464 SUPERFAMILY SSF75304 12 454 1.96E-106 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS25520 6e386305a3dcb172f59dfef06a3d02b9 464 Gene3D G3DSA:3.90.1300.10 13 457 1.6E-106 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS23645 4ae256729fbb66da12f1022eee0142fc 259 Pfam PF04367 Protein of unknown function (DUF502) 80 187 1.5E-32 T 06-07-2017 IPR007462 Protein of unknown function DUF502 CAK95_RS08235 bec714de60b0683fc53be442f79d39fd 281 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 249 6.8E-70 T 06-07-2017 CAK95_RS08235 bec714de60b0683fc53be442f79d39fd 281 SUPERFAMILY SSF51621 8 260 2.41E-63 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS08235 bec714de60b0683fc53be442f79d39fd 281 Gene3D G3DSA:3.20.20.60 7 231 3.9E-61 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS20250 277edc56f55989e2c6986a79c9a61dec 243 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 222 2.0E-60 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK95_RS05925 f3749b56b101f3cd81dcb010060073e7 203 Pfam PF01047 MarR family 62 119 1.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS05925 f3749b56b101f3cd81dcb010060073e7 203 SMART SM00347 54 154 2.3E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS05925 f3749b56b101f3cd81dcb010060073e7 203 SUPERFAMILY SSF46785 32 169 3.31E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05925 f3749b56b101f3cd81dcb010060073e7 203 Gene3D G3DSA:1.10.10.10 31 169 8.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 Gene3D G3DSA:3.90.380.10 163 447 5.7E-61 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 SUPERFAMILY SSF55961 169 447 3.69E-50 T 06-07-2017 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 Pfam PF00355 Rieske [2Fe-2S] domain 52 135 1.2E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 36 61 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 153 179 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 108 128 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 66 81 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 87 107 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 195 217 2.3E-34 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 Gene3D G3DSA:2.102.10.10 50 162 2.1E-35 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 SUPERFAMILY SSF50022 19 168 4.45E-45 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS27560 9c3e94a700a734bcc3b2ff7c99cf2c18 449 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 200 402 3.8E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAK95_RS08015 fc3a1f58c059cb40a43ecbb6edea576f 177 Pfam PF13523 Acetyltransferase (GNAT) domain 16 157 6.1E-25 T 06-07-2017 CAK95_RS08015 fc3a1f58c059cb40a43ecbb6edea576f 177 Gene3D G3DSA:3.40.630.30 6 170 8.4E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08015 fc3a1f58c059cb40a43ecbb6edea576f 177 SMART SM01006 11 54 3.1E-4 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain CAK95_RS08015 fc3a1f58c059cb40a43ecbb6edea576f 177 SUPERFAMILY SSF55729 7 170 1.38E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08365 661311f0280791fc15671d7db66937a4 130 Gene3D G3DSA:3.30.1330.40 5 129 6.6E-35 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS08365 661311f0280791fc15671d7db66937a4 130 SUPERFAMILY SSF55298 6 129 1.18E-36 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS08365 661311f0280791fc15671d7db66937a4 130 Pfam PF01042 Endoribonuclease L-PSP 17 128 1.2E-28 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 Pfam PF03466 LysR substrate binding domain 92 296 4.0E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 Gene3D G3DSA:1.10.10.10 6 85 9.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 SUPERFAMILY SSF46785 6 114 7.07E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 Gene3D G3DSA:3.40.190.10 198 268 9.9E-7 T 06-07-2017 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 Gene3D G3DSA:3.40.190.10 86 197 2.1E-17 T 06-07-2017 CAK95_RS10150 557c595c5d69786bb66caee4a23f625a 334 SUPERFAMILY SSF53850 92 295 9.99E-33 T 06-07-2017 CAK95_RS01910 d95eb7f00901d6469270a94568b1c1d6 260 SUPERFAMILY SSF110399 1 240 6.8E-84 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAK95_RS01910 d95eb7f00901d6469270a94568b1c1d6 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 249 1.2E-107 T 06-07-2017 CAK95_RS01910 d95eb7f00901d6469270a94568b1c1d6 260 Gene3D G3DSA:3.20.20.70 1 257 2.9E-55 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS01910 d95eb7f00901d6469270a94568b1c1d6 260 Hamap MF_00443 Thiazole synthase [thiG]. 1 255 42.598 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAK95_RS21520 886ab26ae5b496b3b51e6ef3e81aaa9f 274 Pfam PF00905 Penicillin binding protein transpeptidase domain 66 268 9.6E-29 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS21520 886ab26ae5b496b3b51e6ef3e81aaa9f 274 SUPERFAMILY SSF56601 57 268 2.54E-32 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS21520 886ab26ae5b496b3b51e6ef3e81aaa9f 274 Gene3D G3DSA:3.40.710.10 33 274 7.5E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS21520 886ab26ae5b496b3b51e6ef3e81aaa9f 274 ProSitePatterns PS00337 Beta-lactamase class-D active site. 72 82 - T 06-07-2017 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 CAK95_RS14855 0201e83ae4d6159b22618743cbfe2434 428 Gene3D G3DSA:3.40.50.2300 210 325 1.5E-10 T 06-07-2017 CAK95_RS14855 0201e83ae4d6159b22618743cbfe2434 428 Pfam PF13458 Periplasmic binding protein 42 399 5.7E-45 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS14855 0201e83ae4d6159b22618743cbfe2434 428 SUPERFAMILY SSF53822 42 384 7.33E-44 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS14855 0201e83ae4d6159b22618743cbfe2434 428 Gene3D G3DSA:3.40.50.2300 326 383 1.0E-18 T 06-07-2017 CAK95_RS14855 0201e83ae4d6159b22618743cbfe2434 428 Gene3D G3DSA:3.40.50.2300 38 174 1.0E-18 T 06-07-2017 CAK95_RS17960 10b5e0dec3fb19ffd63227f4f5e55a97 304 Pfam PF05235 CHAD domain 22 242 3.0E-27 T 06-07-2017 IPR007899 CHAD domain CAK95_RS17960 10b5e0dec3fb19ffd63227f4f5e55a97 304 SMART SM00880 16 279 7.9E-17 T 06-07-2017 IPR007899 CHAD domain CAK95_RS08240 b3557453cf9a96617294194d5b529641 221 SUPERFAMILY SSF55729 37 185 1.35E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS08240 b3557453cf9a96617294194d5b529641 221 Pfam PF13302 Acetyltransferase (GNAT) domain 40 160 9.7E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS08240 b3557453cf9a96617294194d5b529641 221 Gene3D G3DSA:3.40.630.30 11 201 1.4E-55 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS13075 d23feeb0045b2c6babf51618ff586a97 156 Pfam PF04982 HPP family 39 152 5.3E-29 T 06-07-2017 IPR007065 HPP CAK95_RS00335 f20b7bd2b49aa03edc9426fbc3bed5fd 339 PIRSF PIRSF017082 8 339 1.8E-58 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00335 f20b7bd2b49aa03edc9426fbc3bed5fd 339 SUPERFAMILY SSF53850 131 295 7.85E-9 T 06-07-2017 CAK95_RS00335 f20b7bd2b49aa03edc9426fbc3bed5fd 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 330 1.3E-56 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18965 aec2bcf8c7dddcbaebf455a87a4479b4 394 Pfam PF04860 Phage portal protein 55 380 7.0E-87 T 06-07-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein CAK95_RS18965 aec2bcf8c7dddcbaebf455a87a4479b4 394 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 46 389 9.6E-72 T 06-07-2017 IPR006427 Phage portal protein, HK97 CAK95_RS19495 0bcca23f8a5d0498aa2b85631079eda1 154 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 35 142 9.8E-27 T 06-07-2017 IPR018754 Protein of unknown function DUF2285 CAK95_RS24930 0f75dd2624268d8709b8201a21c957fb 389 SUPERFAMILY SSF111369 48 259 1.31E-8 T 06-07-2017 CAK95_RS24930 0f75dd2624268d8709b8201a21c957fb 389 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 379 6.2E-32 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS24930 0f75dd2624268d8709b8201a21c957fb 389 Gene3D G3DSA:2.40.50.100 58 89 5.1E-9 T 06-07-2017 CAK95_RS24930 0f75dd2624268d8709b8201a21c957fb 389 Gene3D G3DSA:2.40.50.100 192 224 5.1E-9 T 06-07-2017 CAK95_RS24930 0f75dd2624268d8709b8201a21c957fb 389 Pfam PF13437 HlyD family secretion protein 195 284 1.8E-13 T 06-07-2017 CAK95_RS05830 ca6f54a7b87f24294a7b0f0ef4660a43 130 Gene3D G3DSA:2.60.40.1470 3 124 2.1E-47 T 06-07-2017 IPR007474 ApaG domain CAK95_RS05830 ca6f54a7b87f24294a7b0f0ef4660a43 130 Hamap MF_00791 Protein ApaG [apaG]. 2 130 32.146 T 06-07-2017 IPR023065 Uncharacterised protein family ApaG CAK95_RS05830 ca6f54a7b87f24294a7b0f0ef4660a43 130 SUPERFAMILY SSF110069 5 125 4.05E-47 T 06-07-2017 IPR007474 ApaG domain CAK95_RS05830 ca6f54a7b87f24294a7b0f0ef4660a43 130 Pfam PF04379 Protein of unknown function (DUF525) 20 104 9.3E-34 T 06-07-2017 IPR007474 ApaG domain CAK95_RS19735 84ef383c741f55f73f2c251a614f09bd 206 SUPERFAMILY SSF53335 29 187 3.65E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS19735 84ef383c741f55f73f2c251a614f09bd 206 Pfam PF08241 Methyltransferase domain 54 138 1.3E-4 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS19735 84ef383c741f55f73f2c251a614f09bd 206 Gene3D G3DSA:3.40.50.150 33 187 4.8E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24305 2ae619754fba15ff1c60ce839c156e0f 372 Gene3D G3DSA:1.10.443.10 227 355 1.2E-16 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS24305 2ae619754fba15ff1c60ce839c156e0f 372 SUPERFAMILY SSF56349 226 359 1.62E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS24305 2ae619754fba15ff1c60ce839c156e0f 372 Pfam PF00589 Phage integrase family 227 352 1.5E-7 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK95_RS24305 2ae619754fba15ff1c60ce839c156e0f 372 SUPERFAMILY SSF56349 54 205 4.24E-7 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK95_RS07715 283b4cd6b86c6dee5359aa547f1dc1f0 132 Pfam PF03928 Haem-degrading 7 128 2.7E-32 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS07715 283b4cd6b86c6dee5359aa547f1dc1f0 132 SUPERFAMILY SSF143744 3 131 5.36E-37 T 06-07-2017 CAK95_RS20210 4f10251411179a21b4617a7678898bec 179 Gene3D G3DSA:1.20.1290.10 33 171 4.1E-21 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS20210 4f10251411179a21b4617a7678898bec 179 SUPERFAMILY SSF69118 3 172 6.96E-25 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS19945 59a21757ddf8a2d28cb7212375bf43b9 241 Pfam PF01988 VIT family 29 234 7.8E-48 T 06-07-2017 IPR008217 Ccc1 family CAK95_RS23320 9b241fac62f88652c79de80f2577d8e1 342 SUPERFAMILY SSF52540 22 236 1.67E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23320 9b241fac62f88652c79de80f2577d8e1 342 Gene3D G3DSA:3.40.50.300 22 189 1.9E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23320 9b241fac62f88652c79de80f2577d8e1 342 Gene3D G3DSA:1.10.8.60 190 236 1.2E-5 T 06-07-2017 CAK95_RS23320 9b241fac62f88652c79de80f2577d8e1 342 Pfam PF13177 DNA polymerase III, delta subunit 25 199 2.0E-30 T 06-07-2017 CAK95_RS27700 2f07383bdcc6306f4cb0ed7d9508196b 191 SUPERFAMILY SSF160519 1 185 2.09E-62 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAK95_RS27700 2f07383bdcc6306f4cb0ed7d9508196b 191 Gene3D G3DSA:3.30.1330.110 1 185 3.4E-68 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAK95_RS27700 2f07383bdcc6306f4cb0ed7d9508196b 191 Pfam PF06684 Amino acid synthesis 5 178 1.9E-64 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAK95_RS28880 d63f582feebbc674cae86d3954daac49 154 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 145 8.2E-29 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS28880 d63f582feebbc674cae86d3954daac49 154 Gene3D G3DSA:3.30.530.20 4 150 6.3E-41 T 06-07-2017 IPR023393 START-like domain CAK95_RS28880 d63f582feebbc674cae86d3954daac49 154 SUPERFAMILY SSF55961 4 147 1.47E-31 T 06-07-2017 CAK95_RS21560 11b9622b8a8ae906c62ce1c4df6d49c4 508 Gene3D G3DSA:3.90.226.10 253 508 9.6E-99 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21560 11b9622b8a8ae906c62ce1c4df6d49c4 508 SUPERFAMILY SSF52096 223 508 6.22E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21560 11b9622b8a8ae906c62ce1c4df6d49c4 508 Pfam PF01039 Carboxyl transferase domain 27 506 7.7E-187 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK95_RS21560 11b9622b8a8ae906c62ce1c4df6d49c4 508 SUPERFAMILY SSF52096 3 248 2.8E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS21560 11b9622b8a8ae906c62ce1c4df6d49c4 508 Gene3D G3DSA:3.90.226.10 2 247 9.9E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS07145 97d1aa87f1a590ff639622ca9e5c7baf 377 Pfam PF06078 Bacterial protein of unknown function (DUF937) 9 136 2.4E-11 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS04480 c4484b0a458b6d6b12f58b216a2d0c3f 294 Gene3D G3DSA:1.10.600.10 16 278 1.0E-44 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS04480 c4484b0a458b6d6b12f58b216a2d0c3f 294 Pfam PF00494 Squalene/phytoene synthase 13 259 1.3E-47 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAK95_RS04480 c4484b0a458b6d6b12f58b216a2d0c3f 294 SUPERFAMILY SSF48576 13 278 1.87E-55 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK95_RS04480 c4484b0a458b6d6b12f58b216a2d0c3f 294 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 11 271 1.9E-83 T 06-07-2017 IPR017827 Squalene synthase HpnC CAK95_RS22595 7ccaca035eaa806c9dc80f786b8b5a87 721 SUPERFAMILY SSF52540 542 681 7.77E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22595 7ccaca035eaa806c9dc80f786b8b5a87 721 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 546 660 9.8E-7 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK95_RS22595 7ccaca035eaa806c9dc80f786b8b5a87 721 Pfam PF02706 Chain length determinant protein 21 193 5.0E-21 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAK95_RS22595 7ccaca035eaa806c9dc80f786b8b5a87 721 Gene3D G3DSA:3.40.50.300 542 681 3.3E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 SUPERFAMILY SSF53335 22 271 3.97E-69 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 Gene3D G3DSA:3.40.50.150 19 271 2.1E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 90 110 3.2E-37 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 225 243 3.2E-37 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 206 223 3.2E-37 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 41 55 3.2E-37 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 248 268 3.2E-37 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 Pfam PF01555 DNA methylase 42 264 3.3E-52 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS11240 e289ce740fe88d0bd516faf992d1c64c 375 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 45 51 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK95_RS17625 8b898f82b418f2fb85de69217eb3748f 413 Pfam PF04932 O-Antigen ligase 187 334 4.8E-19 T 06-07-2017 IPR007016 O-antigen ligase-related CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 SMART SM00387 361 474 1.4E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 SUPERFAMILY SSF55874 315 472 1.05E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 3.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 Gene3D G3DSA:3.30.565.10 323 471 5.5E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS12205 88ac01bd7c5ea8dfa32a43f2669cd978 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 472 1.1E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS05155 6801fdfdb70f268803edd465a8b13fc5 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 89 6.1E-12 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 283 7.4E-24 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 SUPERFAMILY SSF161111 4 203 4.32E-49 T 06-07-2017 CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 Gene3D G3DSA:3.30.70.1350 203 285 5.2E-27 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 Pfam PF01545 Cation efflux family 12 202 3.5E-35 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 Gene3D G3DSA:1.20.1510.10 11 202 1.7E-40 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 SUPERFAMILY SSF160240 205 284 4.05E-22 T 06-07-2017 CAK95_RS25340 d58b092bce3d5fcc7127639f2d43a7bc 295 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 284 7.8E-67 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS19725 82ef534a4849b97d4f279571d7e0f22e 320 SUPERFAMILY SSF141523 37 156 1.01E-8 T 06-07-2017 CAK95_RS10720 aea0a564c34c1054824273449bda831d 154 Pfam PF04892 VanZ like family 78 145 1.3E-6 T 06-07-2017 IPR006976 VanZ-like CAK95_RS01975 c6f10b56f09993413e3e9dcf6eee9adf 141 Gene3D G3DSA:2.60.120.10 36 114 2.4E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS01975 c6f10b56f09993413e3e9dcf6eee9adf 141 Pfam PF07883 Cupin domain 44 111 1.2E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS01975 c6f10b56f09993413e3e9dcf6eee9adf 141 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 47 98 6.0E-4 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK95_RS01975 c6f10b56f09993413e3e9dcf6eee9adf 141 SUPERFAMILY SSF51182 40 119 4.82E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS26910 8b25618a8b5be32659b9326fd8589bf5 271 SUPERFAMILY SSF53335 37 182 2.41E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26910 8b25618a8b5be32659b9326fd8589bf5 271 Gene3D G3DSA:3.40.50.150 39 179 4.6E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26910 8b25618a8b5be32659b9326fd8589bf5 271 Pfam PF13489 Methyltransferase domain 34 173 7.7E-9 T 06-07-2017 CAK95_RS17205 7912adf52a5edf93bf2055b57688808f 320 SUPERFAMILY SSF53850 29 252 2.44E-26 T 06-07-2017 CAK95_RS17205 7912adf52a5edf93bf2055b57688808f 320 Gene3D G3DSA:3.40.190.10 115 236 2.0E-8 T 06-07-2017 CAK95_RS17205 7912adf52a5edf93bf2055b57688808f 320 Pfam PF09084 NMT1/THI5 like 47 250 9.5E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 9.5E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 SUPERFAMILY SSF51735 111 287 1.03E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 SMART SM00829 10 323 2.5E-47 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 Gene3D G3DSA:3.40.50.720 148 262 9.7E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 Pfam PF00107 Zinc-binding dehydrogenase 151 266 1.2E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 Gene3D G3DSA:3.90.180.10 1 147 3.3E-49 T 06-07-2017 IPR011032 GroES-like CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 SUPERFAMILY SSF50129 1 139 9.12E-40 T 06-07-2017 IPR011032 GroES-like CAK95_RS00115 d2d88035020dbc341b5965e4b66b3cdc 343 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 4.7E-121 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 SUPERFAMILY SSF55785 222 344 2.86E-13 T 06-07-2017 IPR000014 PAS domain CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 Pfam PF08448 PAS fold 124 216 2.1E-7 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 Pfam PF08448 PAS fold 245 348 1.1E-14 T 06-07-2017 IPR013656 PAS fold-4 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 237 353 2.6E-7 T 06-07-2017 IPR000014 PAS domain CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 SUPERFAMILY SSF55785 101 215 4.57E-6 T 06-07-2017 IPR000014 PAS domain CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 Gene3D G3DSA:3.30.450.20 226 346 5.4E-16 T 06-07-2017 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 Gene3D G3DSA:3.30.450.20 103 215 2.0E-7 T 06-07-2017 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 Pfam PF07536 HWE histidine kinase 359 441 1.1E-26 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS11095 f0ac1ba61c431511e087c207777bb3f6 550 SMART SM00911 359 441 4.6E-39 T 06-07-2017 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CAK95_RS03305 8c3bc605a9791fdb2acbe5d9e3f75f94 257 Pfam PF05138 Phenylacetic acid catabolic protein 33 236 1.7E-15 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAK95_RS03305 8c3bc605a9791fdb2acbe5d9e3f75f94 257 SUPERFAMILY SSF47240 29 235 4.56E-32 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS03305 8c3bc605a9791fdb2acbe5d9e3f75f94 257 Gene3D G3DSA:1.20.1260.10 27 241 1.4E-19 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS20625 085f83fd5858db7d4dd68748cd33f78a 472 SUPERFAMILY SSF56059 13 209 7.07E-64 T 06-07-2017 CAK95_RS20625 085f83fd5858db7d4dd68748cd33f78a 472 SUPERFAMILY SSF56059 317 463 7.07E-64 T 06-07-2017 CAK95_RS20625 085f83fd5858db7d4dd68748cd33f78a 472 Pfam PF14403 Circularly permuted ATP-grasp type 2 71 448 6.1E-162 T 06-07-2017 IPR025841 Circularly permuted ATP-grasp type 2 CAK95_RS20625 085f83fd5858db7d4dd68748cd33f78a 472 PIRSF PIRSF005522 1 472 4.1E-226 T 06-07-2017 IPR016450 Uncharacterised conserved protein UCP005522 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 Gene3D G3DSA:3.40.50.300 361 596 9.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 Pfam PF00005 ABC transporter 378 531 1.9E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 SUPERFAMILY SSF90123 28 339 5.36E-51 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 Gene3D G3DSA:1.20.1560.10 29 333 3.1E-42 T 06-07-2017 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 Pfam PF00664 ABC transporter transmembrane region 41 304 4.2E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 SMART SM00382 386 577 5.0E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16335 41079ff3bbc98360a0a1846711c19f5b 615 SUPERFAMILY SSF52540 351 601 1.05E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27675 697d07116e397386aba0d92d7f12fee3 292 Gene3D G3DSA:3.40.50.1820 4 242 4.3E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27675 697d07116e397386aba0d92d7f12fee3 292 SUPERFAMILY SSF53474 9 265 5.12E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27675 697d07116e397386aba0d92d7f12fee3 292 Pfam PF07859 alpha/beta hydrolase fold 47 240 1.4E-49 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS01640 a07476f74ba8659845e251c46af1e320 83 SUPERFAMILY SSF54285 2 81 2.06E-17 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAK95_RS01640 a07476f74ba8659845e251c46af1e320 83 Gene3D G3DSA:3.10.20.30 2 83 3.3E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS01640 a07476f74ba8659845e251c46af1e320 83 Pfam PF02597 ThiS family 4 83 1.6E-15 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAK95_RS01640 a07476f74ba8659845e251c46af1e320 83 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 83 5.1E-23 T 06-07-2017 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CAK95_RS24725 d1b406854c412277152af539bebbab03 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.5E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS24725 d1b406854c412277152af539bebbab03 315 SUPERFAMILY SSF46785 4 111 5.96E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS24725 d1b406854c412277152af539bebbab03 315 Gene3D G3DSA:3.40.190.10 89 177 4.9E-8 T 06-07-2017 CAK95_RS24725 d1b406854c412277152af539bebbab03 315 Gene3D G3DSA:3.40.190.10 178 263 9.2E-23 T 06-07-2017 CAK95_RS24725 d1b406854c412277152af539bebbab03 315 SUPERFAMILY SSF53850 89 300 6.52E-40 T 06-07-2017 CAK95_RS24725 d1b406854c412277152af539bebbab03 315 Pfam PF03466 LysR substrate binding domain 89 295 7.9E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS24725 d1b406854c412277152af539bebbab03 315 Gene3D G3DSA:1.10.10.10 3 83 4.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS08080 84851e4702d43e5f2183e7700ef9bac1 128 Pfam PF04480 Protein of unknown function (DUF559) 3 109 6.5E-33 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK95_RS08080 84851e4702d43e5f2183e7700ef9bac1 128 SUPERFAMILY SSF52980 4 111 3.38E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS27805 cdf8d50d6cbdfaa28fbd734af351d134 337 SUPERFAMILY SSF102198 263 318 6.02E-42 T 06-07-2017 CAK95_RS27805 cdf8d50d6cbdfaa28fbd734af351d134 337 SUPERFAMILY SSF102198 56 219 6.02E-42 T 06-07-2017 CAK95_RS27805 cdf8d50d6cbdfaa28fbd734af351d134 337 Gene3D G3DSA:3.50.30.50 263 319 1.2E-50 T 06-07-2017 CAK95_RS27805 cdf8d50d6cbdfaa28fbd734af351d134 337 Gene3D G3DSA:3.50.30.50 57 219 1.2E-50 T 06-07-2017 CAK95_RS27805 cdf8d50d6cbdfaa28fbd734af351d134 337 Pfam PF04199 Putative cyclase 59 218 1.1E-26 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS10340 dee858bb428b03febac16d9486013958 200 Pfam PF05233 PHB accumulation regulatory domain 74 113 1.0E-19 T 06-07-2017 IPR007897 PHB accumulation regulatory CAK95_RS10340 dee858bb428b03febac16d9486013958 200 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 9 68 2.5E-29 T 06-07-2017 IPR012909 PHA accumulation regulator DNA-binding, N-terminal CAK95_RS10340 dee858bb428b03febac16d9486013958 200 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 10 115 1.1E-45 T 06-07-2017 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 247 383 3.7E-40 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 SUPERFAMILY SSF56645 24 215 1.57E-32 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 Gene3D G3DSA:1.10.540.10 13 119 1.7E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 SUPERFAMILY SSF47203 237 379 1.11E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 Gene3D G3DSA:1.20.140.10 209 401 2.6E-45 T 06-07-2017 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 PIRSF PIRSF016578 6 403 1.9E-128 T 06-07-2017 CAK95_RS00315 a8e2853547e23fc136288f9ed08f1f85 403 Gene3D G3DSA:2.40.110.10 127 208 8.5E-23 T 06-07-2017 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 136 1.1E-23 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 458 628 3.5E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 SUPERFAMILY SSF56003 128 790 1.23E-152 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 728 3.5E-129 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.90.1170.50 7 124 2.9E-34 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 SMART SM01008 25 136 3.7E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 365 457 5.7E-53 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 643 792 5.7E-53 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 289 363 2.7E-25 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 125 180 2.7E-25 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 Gene3D G3DSA:3.30.365.10 181 285 1.4E-21 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK95_RS28890 36d5cb60a61efb1de0cef3f7d64ede08 801 SUPERFAMILY SSF54665 9 157 3.01E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK95_RS19935 d9546f82b2eb5918a76ebde3aae10c7b 179 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 106 162 2.7E-16 T 06-07-2017 IPR018637 Domain of unknown function DUF2059 CAK95_RS21475 950e95e18126e219a7480f8ccbe98edb 174 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 20 144 4.2E-20 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS21475 950e95e18126e219a7480f8ccbe98edb 174 Gene3D G3DSA:3.30.530.20 10 154 2.6E-31 T 06-07-2017 IPR023393 START-like domain CAK95_RS21475 950e95e18126e219a7480f8ccbe98edb 174 SUPERFAMILY SSF55961 8 148 2.67E-34 T 06-07-2017 CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 SMART SM00418 8 89 5.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 SUPERFAMILY SSF46785 2 93 5.36E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 Pfam PF12840 Helix-turn-helix domain 9 69 4.0E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.3E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.3E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.3E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK95_RS05340 3aa0d5ef62f9c4bd9deee9b8efe4aa22 107 Gene3D G3DSA:1.10.10.10 2 101 7.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28605 bcbe8a006f70594a949ba704b29031df 233 SUPERFAMILY SSF52499 19 223 1.7E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS28605 bcbe8a006f70594a949ba704b29031df 233 Gene3D G3DSA:3.40.50.850 20 225 5.4E-42 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS28605 bcbe8a006f70594a949ba704b29031df 233 Pfam PF00857 Isochorismatase family 25 216 6.4E-31 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS10090 ce5f1ab463c9c34f29d2adf72aa85005 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 4.4E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10090 ce5f1ab463c9c34f29d2adf72aa85005 330 PIRSF PIRSF017082 1 324 8.6E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10090 ce5f1ab463c9c34f29d2adf72aa85005 330 SUPERFAMILY SSF53850 113 287 4.07E-10 T 06-07-2017 CAK95_RS25355 221ff5020618e5851a7a42dfdd1b8412 197 SUPERFAMILY SSF52218 8 178 2.17E-44 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS25355 221ff5020618e5851a7a42dfdd1b8412 197 Gene3D G3DSA:3.40.50.360 4 187 1.0E-47 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS25355 221ff5020618e5851a7a42dfdd1b8412 197 Pfam PF03358 NADPH-dependent FMN reductase 8 152 5.5E-35 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS21360 f26113a0de22ce6fb27fb78660e07792 212 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 150 5.6E-36 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAK95_RS21360 f26113a0de22ce6fb27fb78660e07792 212 SUPERFAMILY SSF52080 5 151 1.83E-41 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAK95_RS21360 f26113a0de22ce6fb27fb78660e07792 212 Gene3D G3DSA:3.100.10.10 32 160 2.4E-24 T 06-07-2017 CAK95_RS21360 f26113a0de22ce6fb27fb78660e07792 212 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 149 1.0E-43 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS21360 f26113a0de22ce6fb27fb78660e07792 212 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 152 20.122 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CAK95_RS25555 0e96bc905a2e210690c1b80ca047fcf0 194 SMART SM00318 60 178 3.6E-9 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS25555 0e96bc905a2e210690c1b80ca047fcf0 194 SUPERFAMILY SSF50199 60 180 9.02E-26 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS25555 0e96bc905a2e210690c1b80ca047fcf0 194 Gene3D G3DSA:2.40.50.90 59 151 1.4E-18 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS25555 0e96bc905a2e210690c1b80ca047fcf0 194 Pfam PF00565 Staphylococcal nuclease homologue 74 177 5.3E-12 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS23230 82ef3021a45f75af5f0329ed955436f0 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 12 141 8.2E-26 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAK95_RS23230 82ef3021a45f75af5f0329ed955436f0 153 Gene3D G3DSA:3.30.530.20 1 150 1.8E-47 T 06-07-2017 IPR023393 START-like domain CAK95_RS23230 82ef3021a45f75af5f0329ed955436f0 153 SUPERFAMILY SSF55961 1 150 1.33E-33 T 06-07-2017 CAK95_RS04740 54d4d740668e7baeb83d7dea435cea10 397 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 305 390 9.9E-14 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CAK95_RS04740 54d4d740668e7baeb83d7dea435cea10 397 Pfam PF01943 Polysaccharide biosynthesis protein 5 243 7.8E-13 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CAK95_RS24545 1132d9e439ee18f1165e57c3ba90df40 173 SUPERFAMILY SSF101386 10 79 1.0E-6 T 06-07-2017 CAK95_RS24545 1132d9e439ee18f1165e57c3ba90df40 173 Gene3D G3DSA:1.10.287.1080 12 79 1.3E-6 T 06-07-2017 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 Pfam PF00672 HAMP domain 341 408 5.2E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 SMART SM00304 360 413 1.4E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 SMART SM00304 441 493 0.0078 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 SMART SM00283 494 741 4.3E-92 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 SUPERFAMILY SSF158472 360 407 6.28E-7 T 06-07-2017 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 Gene3D G3DSA:1.10.287.950 509 713 2.5E-60 T 06-07-2017 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 SUPERFAMILY SSF58104 461 742 3.49E-72 T 06-07-2017 CAK95_RS25160 8ab58d44a6cd66a3d1e5fe1c8a20c381 806 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 563 740 1.5E-56 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS11140 9dfd65156b7cab5e84b5c73108531e0b 76 Gene3D G3DSA:3.30.70.790 1 74 1.9E-32 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAK95_RS11140 9dfd65156b7cab5e84b5c73108531e0b 76 SUPERFAMILY SSF54913 1 73 2.89E-23 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS11140 9dfd65156b7cab5e84b5c73108531e0b 76 Pfam PF09413 Putative prokaryotic signal transducing protein 1 65 6.6E-20 T 06-07-2017 IPR018551 Domain of unknown function DUF2007 CAK95_RS25475 0dffb77cb33fe92d48d1c00ea07d4791 339 Pfam PF09084 NMT1/THI5 like 41 245 3.4E-33 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS25475 0dffb77cb33fe92d48d1c00ea07d4791 339 Gene3D G3DSA:3.40.190.10 110 231 3.0E-16 T 06-07-2017 CAK95_RS25475 0dffb77cb33fe92d48d1c00ea07d4791 339 SUPERFAMILY SSF53850 33 256 2.9E-38 T 06-07-2017 CAK95_RS26950 98ac5afc4fde74e93d459a20e0f5c365 215 SUPERFAMILY SSF53335 54 164 9.6E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26950 98ac5afc4fde74e93d459a20e0f5c365 215 Gene3D G3DSA:3.40.50.150 50 192 5.4E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26950 98ac5afc4fde74e93d459a20e0f5c365 215 Pfam PF13649 Methyltransferase domain 58 154 1.8E-18 T 06-07-2017 CAK95_RS16290 42ed7f8a13ff0ad43f270fd1815f944c 122 SUPERFAMILY SSF46785 4 111 1.49E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16290 42ed7f8a13ff0ad43f270fd1815f944c 122 Gene3D G3DSA:1.10.10.10 3 114 1.9E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16290 42ed7f8a13ff0ad43f270fd1815f944c 122 Pfam PF01638 HxlR-like helix-turn-helix 18 104 9.8E-28 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS10775 5af19fb4010c57a673f5d5c56ee7fc39 352 SUPERFAMILY SSF51735 1 297 1.33E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS10775 5af19fb4010c57a673f5d5c56ee7fc39 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 4.7E-35 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS10775 5af19fb4010c57a673f5d5c56ee7fc39 352 Gene3D G3DSA:3.40.50.720 1 281 4.1E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 Gene3D G3DSA:1.20.1250.20 3 185 8.0E-30 T 06-07-2017 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 PRINTS PR01035 Tetracycline resistance protein signature 130 152 2.3E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 PRINTS PR01035 Tetracycline resistance protein signature 41 60 2.3E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 PRINTS PR01035 Tetracycline resistance protein signature 327 350 2.3E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 PRINTS PR01035 Tetracycline resistance protein signature 244 264 2.3E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 Pfam PF07690 Major Facilitator Superfamily 9 232 4.5E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 Gene3D G3DSA:1.20.1250.20 210 385 4.2E-19 T 06-07-2017 CAK95_RS23145 09d5408072fa7e0ab81ac679b677b8db 388 SUPERFAMILY SSF103473 4 386 3.4E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS19555 d3719bc5c50cc32368c1cc3f0f0e2347 145 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 42 6.2E-5 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK95_RS00180 e4196ff59a8a8f460be806f43b1c36c5 186 SUPERFAMILY SSF52218 3 174 2.01E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS00180 e4196ff59a8a8f460be806f43b1c36c5 186 Gene3D G3DSA:3.40.50.360 1 180 1.4E-48 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS00180 e4196ff59a8a8f460be806f43b1c36c5 186 Pfam PF03358 NADPH-dependent FMN reductase 3 147 5.8E-33 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 3 258 9.0E-109 T 06-07-2017 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 SUPERFAMILY SSF117143 93 221 2.88E-33 T 06-07-2017 CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 259 4.1E-22 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 10 30 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 145 243 2.9E-27 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 136 3.8E-45 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAK95_RS18205 2e8233546f4c2f0f681939aef9f1bb60 262 Pfam PF00460 Flagella basal body rod protein 4 34 4.6E-10 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAK95_RS22220 c3ef62321148ec2774a1fcfad1f8db6a 278 SUPERFAMILY SSF56925 62 269 5.18E-28 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS22220 c3ef62321148ec2774a1fcfad1f8db6a 278 Gene3D G3DSA:2.40.160.20 33 276 6.0E-36 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS22220 c3ef62321148ec2774a1fcfad1f8db6a 278 Pfam PF13505 Outer membrane protein beta-barrel domain 32 265 6.7E-18 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS04550 ccdf9b05bd9c2942e5ecc27ce31ec431 356 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 55 318 6.4E-27 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS07795 f2418be0e4d8b63e7cb3b9345178816b 256 SUPERFAMILY SSF47413 14 71 3.66E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS07795 f2418be0e4d8b63e7cb3b9345178816b 256 Pfam PF13560 Helix-turn-helix domain 25 70 1.2E-6 T 06-07-2017 CAK95_RS07795 f2418be0e4d8b63e7cb3b9345178816b 256 Gene3D G3DSA:1.10.260.40 19 70 2.7E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS07795 f2418be0e4d8b63e7cb3b9345178816b 256 SMART SM00530 19 74 2.0E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS25100 07fa8910c721294d787773eb5929412b 143 SUPERFAMILY SSF55961 7 139 4.32E-41 T 06-07-2017 CAK95_RS25100 07fa8910c721294d787773eb5929412b 143 Gene3D G3DSA:3.30.530.20 2 139 1.1E-41 T 06-07-2017 IPR023393 START-like domain CAK95_RS25100 07fa8910c721294d787773eb5929412b 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 139 5.5E-28 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS14890 bceb15537d9800820e96a795f13b92b4 309 Pfam PF09084 NMT1/THI5 like 36 252 2.3E-33 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS14890 bceb15537d9800820e96a795f13b92b4 309 SUPERFAMILY SSF53850 24 252 2.11E-36 T 06-07-2017 CAK95_RS14890 bceb15537d9800820e96a795f13b92b4 309 Gene3D G3DSA:3.40.190.10 111 233 1.3E-18 T 06-07-2017 CAK95_RS03050 f75e24b5f9d3e7f13e0b2c9b91522a8b 272 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 44 119 2.3E-6 T 06-07-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 Gene3D G3DSA:3.40.50.300 133 235 4.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 Gene3D G3DSA:3.40.50.300 315 375 4.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 SUPERFAMILY SSF52540 130 270 6.99E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 SUPERFAMILY SSF52540 301 374 6.99E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 Gene3D G3DSA:3.40.50.300 8 128 4.3E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 SUPERFAMILY SSF52540 3 166 3.2E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 Pfam PF13604 AAA domain 31 186 4.9E-25 T 06-07-2017 CAK95_RS20280 5778797e6949fb41aef5ae0f8d443dfa 376 Pfam PF13538 UvrD-like helicase C-terminal domain 326 374 4.4E-19 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 Gene3D G3DSA:3.40.50.300 7 245 1.1E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 SMART SM00382 33 231 1.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 SUPERFAMILY SSF52540 8 244 2.15E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 Pfam PF00005 ABC transporter 24 174 1.5E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS21135 b931be9c6a6f1034e68df8b0f7cfa142 249 PIRSF PIRSF039085 5 249 1.1E-108 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAK95_RS00645 15103b93b9261aeff7f6a983e36ffab7 545 Gene3D G3DSA:1.10.101.10 388 437 3.5E-4 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS00645 15103b93b9261aeff7f6a983e36ffab7 545 Gene3D G3DSA:3.40.50.1460 26 161 9.4E-17 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS00645 15103b93b9261aeff7f6a983e36ffab7 545 Pfam PF00656 Caspase domain 29 246 7.2E-29 T 06-07-2017 CAK95_RS00645 15103b93b9261aeff7f6a983e36ffab7 545 SUPERFAMILY SSF52129 23 257 2.99E-47 T 06-07-2017 IPR029030 Caspase-like domain CAK95_RS06555 958a29420e3cc1763a7021229379cf92 160 SUPERFAMILY SSF63882 23 159 2.49E-25 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06555 958a29420e3cc1763a7021229379cf92 160 Pfam PF03453 MoeA N-terminal region (domain I and II) 25 159 2.7E-17 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK95_RS06555 958a29420e3cc1763a7021229379cf92 160 Gene3D G3DSA:3.90.105.10 34 55 2.8E-5 T 06-07-2017 CAK95_RS06555 958a29420e3cc1763a7021229379cf92 160 Gene3D G3DSA:3.90.105.10 136 160 2.8E-5 T 06-07-2017 CAK95_RS06555 958a29420e3cc1763a7021229379cf92 160 Gene3D G3DSA:2.170.190.11 56 135 1.6E-5 T 06-07-2017 CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 321 407 3.9E-33 T 06-07-2017 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 SUPERFAMILY SSF53213 2 279 2.49E-89 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 Gene3D G3DSA:3.40.830.10 1 291 7.0E-106 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 266 1.8E-63 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 SUPERFAMILY SSF48076 293 417 3.01E-44 T 06-07-2017 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CAK95_RS21960 7753bc7133f87fbf46313e612c07a178 432 Gene3D G3DSA:1.10.700.10 292 421 1.0E-51 T 06-07-2017 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CAK95_RS12985 6209b12c240931caccb626a2087dabc7 332 PIRSF PIRSF017082 4 331 1.5E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12985 6209b12c240931caccb626a2087dabc7 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 327 3.4E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12985 6209b12c240931caccb626a2087dabc7 332 SUPERFAMILY SSF53850 120 292 1.7E-10 T 06-07-2017 CAK95_RS19110 dbaf4e7a1c5e82e6afad69000648bf64 230 SUPERFAMILY SSF52540 50 224 2.16E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS19110 dbaf4e7a1c5e82e6afad69000648bf64 230 Pfam PF13469 Sulfotransferase family 45 155 2.1E-7 T 06-07-2017 CAK95_RS19110 dbaf4e7a1c5e82e6afad69000648bf64 230 Gene3D G3DSA:3.40.50.300 59 222 5.3E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06260 1c00b02d859cfb6f85bbfd44176c610c 169 Pfam PF02566 OsmC-like protein 64 164 4.7E-19 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS06260 1c00b02d859cfb6f85bbfd44176c610c 169 Gene3D G3DSA:3.30.300.20 2 157 1.3E-44 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK95_RS06260 1c00b02d859cfb6f85bbfd44176c610c 169 SUPERFAMILY SSF82784 8 166 1.02E-35 T 06-07-2017 IPR003718 OsmC/Ohr family CAK95_RS20360 639544175215d5c7cdaeacb1d35a7622 291 Gene3D G3DSA:3.20.20.140 7 289 2.1E-82 T 06-07-2017 CAK95_RS20360 639544175215d5c7cdaeacb1d35a7622 291 Pfam PF04909 Amidohydrolase 24 287 8.6E-40 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS20360 639544175215d5c7cdaeacb1d35a7622 291 SUPERFAMILY SSF51556 20 287 3.32E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS15805 f53ffa61d033320b186c028633cdb65a 422 Pfam PF05987 Bacterial protein of unknown function (DUF898) 18 416 4.6E-61 T 06-07-2017 IPR010295 Protein of unknown function DUF898 CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 Pfam PF00912 Transglycosylase 59 226 1.7E-49 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 602 682 8.6E-19 T 06-07-2017 IPR009647 Penicillin-binding, C-terminal CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 Gene3D G3DSA:3.40.710.10 230 571 4.7E-61 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 SUPERFAMILY SSF53955 38 259 8.15E-64 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 Gene3D G3DSA:1.10.3810.10 58 229 4.1E-51 T 06-07-2017 CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 34 573 1.3E-215 T 06-07-2017 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 SUPERFAMILY SSF56601 208 230 1.89E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 SUPERFAMILY SSF56601 257 580 1.89E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS24250 53952bed0f117a33b59508bc19ca57fd 687 Pfam PF00905 Penicillin binding protein transpeptidase domain 303 422 9.4E-13 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 Gene3D G3DSA:1.10.760.10 18 158 1.1E-31 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 Gene3D G3DSA:1.10.760.10 202 229 1.1E-31 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 7 239 9.5E-105 T 06-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 7 232 5.6E-97 T 06-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 SUPERFAMILY SSF46626 217 228 2.0E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS16720 c68a26aba9ded974d9a2d6b5658c8b19 244 SUPERFAMILY SSF46626 20 173 2.0E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 Gene3D G3DSA:1.10.287.950 482 686 2.6E-59 T 06-07-2017 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 SMART SM00304 414 466 1.9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 SMART SM00304 300 352 0.69 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 526 708 4.0E-57 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 Pfam PF00672 HAMP domain 280 342 1.2E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 SMART SM00283 467 714 3.2E-87 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 SUPERFAMILY SSF58104 434 715 5.89E-71 T 06-07-2017 CAK95_RS03950 9c6d062d0080dab9b3b760964ae54935 767 Pfam PF12729 Four helix bundle sensory module for signal transduction 88 254 5.7E-10 T 06-07-2017 IPR024478 4HB MCP domain CAK95_RS11975 03ca50c67849ae1d76d9b8163339962c 94 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 7 79 3.0E-21 T 06-07-2017 IPR011893 Selenoprotein, Rdx type CAK95_RS11975 03ca50c67849ae1d76d9b8163339962c 94 Gene3D G3DSA:3.40.30.10 3 93 1.6E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11975 03ca50c67849ae1d76d9b8163339962c 94 SUPERFAMILY SSF52833 5 89 2.46E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS11975 03ca50c67849ae1d76d9b8163339962c 94 Pfam PF10262 Rdx family 6 80 4.4E-30 T 06-07-2017 IPR011893 Selenoprotein, Rdx type CAK95_RS15210 e6a2894c2a9a8afb701f244f62d7be2b 305 Pfam PF10908 Protein of unknown function (DUF2778) 183 285 4.2E-24 T 06-07-2017 IPR021225 Protein of unknown function DUF2778 CAK95_RS10280 993e6a0524bfd5993ca9adc435fca026 423 Pfam PF04551 GcpE protein 20 388 1.1E-108 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK95_RS10280 993e6a0524bfd5993ca9adc435fca026 423 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 17 403 1.4E-123 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK95_RS10280 993e6a0524bfd5993ca9adc435fca026 423 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 13 407 29.514 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK95_RS10280 993e6a0524bfd5993ca9adc435fca026 423 SUPERFAMILY SSF56014 304 396 2.22E-6 T 06-07-2017 CAK95_RS10280 993e6a0524bfd5993ca9adc435fca026 423 PIRSF PIRSF004640 7 414 1.4E-125 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK95_RS08415 3f199159f0c78cc69ee850906277fe9d 633 Pfam PF01103 Surface antigen 329 633 3.0E-49 T 06-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 CAK95_RS08415 3f199159f0c78cc69ee850906277fe9d 633 Gene3D G3DSA:2.40.160.50 316 633 7.9E-27 T 06-07-2017 CAK95_RS00995 e79a13f4203429484a6227e28b26ce96 268 Gene3D G3DSA:3.60.21.10 1 247 7.4E-37 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS00995 e79a13f4203429484a6227e28b26ce96 268 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 252 36.398 T 06-07-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CAK95_RS00995 e79a13f4203429484a6227e28b26ce96 268 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 7.8E-17 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS00995 e79a13f4203429484a6227e28b26ce96 268 SUPERFAMILY SSF56300 1 251 6.53E-52 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS00620 ce83ea4a7920cdc92ea7252f69de8d65 316 Pfam PF01882 Protein of unknown function DUF58 56 142 1.4E-17 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAK95_RS27730 65f3869aaa33d827c165e96568fa00a9 286 SUPERFAMILY SSF53474 3 272 8.38E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27730 65f3869aaa33d827c165e96568fa00a9 286 Pfam PF00561 alpha/beta hydrolase fold 22 258 3.4E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS27730 65f3869aaa33d827c165e96568fa00a9 286 Gene3D G3DSA:3.40.50.1820 6 271 6.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS17175 93348b87b725738364ada2436a412d9b 334 PIRSF PIRSF017082 1 310 1.1E-49 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17175 93348b87b725738364ada2436a412d9b 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 289 7.8E-32 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13600 c30c127d1bef360fa013115b4d343763 294 Pfam PF00950 ABC 3 transport family 13 268 3.0E-82 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAK95_RS13600 c30c127d1bef360fa013115b4d343763 294 SUPERFAMILY SSF81345 5 264 1.27E-37 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS13600 c30c127d1bef360fa013115b4d343763 294 Gene3D G3DSA:1.10.3470.10 64 247 9.9E-8 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS13275 3dae466596f4041f685e926b63f81783 506 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 229 1.4E-31 T 06-07-2017 CAK95_RS10420 3f396f9a6fafb831891dc16884ea5fd3 115 SUPERFAMILY SSF50685 25 106 1.26E-15 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS10420 3f396f9a6fafb831891dc16884ea5fd3 115 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 25 111 3.8E-35 T 06-07-2017 IPR012997 Rare lipoprotein A CAK95_RS10420 3f396f9a6fafb831891dc16884ea5fd3 115 Pfam PF03330 Lytic transglycolase 24 111 2.1E-23 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS10420 3f396f9a6fafb831891dc16884ea5fd3 115 Gene3D G3DSA:2.40.40.10 62 106 3.0E-7 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS08300 5a69c3cf630caf28fe2fbbddb9850d37 272 Gene3D G3DSA:3.40.250.10 6 105 8.4E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS08300 5a69c3cf630caf28fe2fbbddb9850d37 272 Pfam PF00581 Rhodanese-like domain 12 100 1.6E-5 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS08300 5a69c3cf630caf28fe2fbbddb9850d37 272 SMART SM00450 7 104 4.7E-10 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS08300 5a69c3cf630caf28fe2fbbddb9850d37 272 Pfam PF09828 Chromate resistance exported protein 122 256 4.5E-47 T 06-07-2017 IPR018634 Chromate resistance exported protein CAK95_RS08300 5a69c3cf630caf28fe2fbbddb9850d37 272 SUPERFAMILY SSF52821 1 154 3.93E-21 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS18680 cab387e2c5542a14644630a04fb9eb13 280 SUPERFAMILY SSF103481 40 135 7.06E-12 T 06-07-2017 CAK95_RS18680 cab387e2c5542a14644630a04fb9eb13 280 Pfam PF00892 EamA-like transporter family 146 278 1.5E-6 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS18680 cab387e2c5542a14644630a04fb9eb13 280 SUPERFAMILY SSF103481 184 278 1.29E-11 T 06-07-2017 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 PIRSF PIRSF006004 20 403 3.8E-139 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 22 389 2.2E-114 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 23 390 70.807 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 Gene3D G3DSA:3.20.20.70 133 376 1.4E-13 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 Pfam PF04055 Radical SAM superfamily 137 317 8.7E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS08770 cbb1d1d5720ec4c6bd1d88088017c7fa 406 SUPERFAMILY SSF102114 130 346 2.09E-12 T 06-07-2017 CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 SUPERFAMILY SSF52540 26 218 5.28E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 Gene3D G3DSA:3.40.50.300 26 218 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 SUPERFAMILY SSF90002 245 337 6.67E-20 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 245 338 9.6E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 SMART SM00833 245 339 5.2E-20 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 28 209 1.5E-43 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK95_RS17155 26960ede4ee59ecaf9f018b9ca740cfa 345 Gene3D G3DSA:3.30.1220.10 237 338 2.2E-23 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK95_RS20090 5e87f34b62ce41ceba276e2f84cf7182 347 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 320 1.0E-51 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS00955 8b9bf1b928d26e3b29f58436a930f765 115 Gene3D G3DSA:3.30.429.10 1 113 3.2E-30 T 06-07-2017 CAK95_RS00955 8b9bf1b928d26e3b29f58436a930f765 115 SUPERFAMILY SSF55331 2 113 1.28E-25 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK95_RS18870 b2a444c01e179ade5c4b662d3ad8b49a 335 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 69 277 7.7E-10 T 06-07-2017 IPR019285 Protein of unknown function DUF2336 CAK95_RS15310 6f6e3ba2ddb595f4983105835da21762 362 Pfam PF06674 Protein of unknown function (DUF1176) 26 358 6.9E-67 T 06-07-2017 IPR009560 Protein of unknown function DUF1176 CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 244 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 310 330 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 255 274 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 123 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 276 293 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 192 1.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 Gene3D G3DSA:3.40.50.720 98 347 1.5E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 114 345 2.2E-55 T 06-07-2017 CAK95_RS17080 cec3a5d3ad10326fea5973b6fb3e9e9f 349 SUPERFAMILY SSF51735 103 348 6.77E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26585 e3ef917f3d139d745ebd5f3e0c18ca5f 274 SUPERFAMILY SSF52540 102 227 4.93E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26585 e3ef917f3d139d745ebd5f3e0c18ca5f 274 SUPERFAMILY SSF52540 4 49 4.93E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26585 e3ef917f3d139d745ebd5f3e0c18ca5f 274 Pfam PF13469 Sulfotransferase family 6 210 5.9E-7 T 06-07-2017 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 SUPERFAMILY SSF100950 2 353 1.81E-111 T 06-07-2017 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 351 1.2E-91 T 06-07-2017 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 Pfam PF01008 Initiation factor 2 subunit family 51 351 7.8E-62 T 06-07-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 Gene3D G3DSA:1.20.120.420 9 163 7.6E-46 T 06-07-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 360 35.446 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 Gene3D G3DSA:3.40.50.10470 164 353 2.4E-60 T 06-07-2017 CAK95_RS06350 80bd9cc1b212a645eff6a643a9df5df8 374 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 350 1.6E-125 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAK95_RS25040 6d75839c5c0fddfb95f2225254625dcf 1191 Pfam PF13502 AsmA-like C-terminal region 1057 1152 1.8E-8 T 06-07-2017 IPR032712 AsmA-like, C-terminal CAK95_RS25040 6d75839c5c0fddfb95f2225254625dcf 1191 Pfam PF13116 Protein of unknown function 519 797 3.3E-9 T 06-07-2017 IPR025263 Domain of unknown function DUF3971 CAK95_RS07905 1d9171ad84458d4808ffeb822fd7aba0 345 SUPERFAMILY SSF53850 31 266 1.14E-30 T 06-07-2017 CAK95_RS07905 1d9171ad84458d4808ffeb822fd7aba0 345 Gene3D G3DSA:3.40.190.10 118 245 3.1E-12 T 06-07-2017 CAK95_RS07905 1d9171ad84458d4808ffeb822fd7aba0 345 Pfam PF09084 NMT1/THI5 like 48 259 5.5E-42 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS03485 9d5716338a145381b2c992e5f483ec90 120 SUPERFAMILY SSF143081 4 81 1.83E-16 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS03485 9d5716338a145381b2c992e5f483ec90 120 Pfam PF02586 SOS response associated peptidase (SRAP) 3 81 9.1E-16 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS03485 9d5716338a145381b2c992e5f483ec90 120 Gene3D G3DSA:3.90.1680.10 5 81 6.8E-16 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK95_RS18165 6a6ee88e3ce9f1ce1d669058ddc25a9b 118 Pfam PF10135 Rod binding protein 51 97 2.3E-10 T 06-07-2017 IPR019301 Flagellar protein FlgJ, N-terminal CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 359 375 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 2.0E-42 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 Gene3D G3DSA:3.50.50.60 306 346 1.5E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 Gene3D G3DSA:3.50.50.60 2 185 1.5E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 Pfam PF01494 FAD binding domain 5 370 3.6E-81 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 SUPERFAMILY SSF51905 6 195 5.27E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 SUPERFAMILY SSF51905 295 383 5.27E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 Gene3D G3DSA:3.30.9.10 356 369 1.7E-7 T 06-07-2017 CAK95_RS04580 0da1f1562962bfcaf5d568fb98b5da93 558 Gene3D G3DSA:3.30.9.10 186 304 1.7E-7 T 06-07-2017 CAK95_RS23575 d97f16e7f051d52374974e836465c0ff 318 Pfam PF03547 Membrane transport protein 9 146 5.6E-8 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAK95_RS23575 d97f16e7f051d52374974e836465c0ff 318 Pfam PF03547 Membrane transport protein 160 304 1.3E-15 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 PIRSF PIRSF001235 5 417 3.2E-129 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 Gene3D G3DSA:3.30.70.360 225 320 1.4E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 SUPERFAMILY SSF55031 212 320 6.28E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 SUPERFAMILY SSF53187 5 222 6.81E-81 T 06-07-2017 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 SUPERFAMILY SSF53187 340 413 6.81E-81 T 06-07-2017 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 Pfam PF01546 Peptidase family M20/M25/M40 78 409 6.5E-33 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 Gene3D G3DSA:3.40.630.10 355 414 5.7E-99 T 06-07-2017 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 Gene3D G3DSA:3.40.630.10 6 224 5.7E-99 T 06-07-2017 CAK95_RS15045 91b9156875ad7fe8fcc1b726b8f40ef9 417 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 9 409 1.6E-109 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAK95_RS25810 e58e1916374dddb2cb01b31c53e53eac 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 7.2E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS25810 e58e1916374dddb2cb01b31c53e53eac 323 PIRSF PIRSF017082 1 323 1.6E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14920 86a8e8767d2084fdd6bb074382260c68 252 Pfam PF00005 ABC transporter 19 160 9.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14920 86a8e8767d2084fdd6bb074382260c68 252 SMART SM00382 28 211 1.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS14920 86a8e8767d2084fdd6bb074382260c68 252 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS14920 86a8e8767d2084fdd6bb074382260c68 252 Gene3D G3DSA:3.40.50.300 2 207 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14920 86a8e8767d2084fdd6bb074382260c68 252 SUPERFAMILY SSF52540 4 230 1.08E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 SMART SM00382 27 200 9.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 SUPERFAMILY SSF52540 3 183 1.97E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 3 196 4.9E-69 T 06-07-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 Gene3D G3DSA:3.40.50.300 3 183 1.5E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07565 d38fc807ee496c25cb8d7414b9f41706 200 Pfam PF00005 ABC transporter 19 154 2.6E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16000 fbf0fb23a62bbe067a03b5e31c741ab3 255 SMART SM00382 28 228 2.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16000 fbf0fb23a62bbe067a03b5e31c741ab3 255 Gene3D G3DSA:3.40.50.300 3 250 1.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16000 fbf0fb23a62bbe067a03b5e31c741ab3 255 SUPERFAMILY SSF52540 4 250 1.2E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16000 fbf0fb23a62bbe067a03b5e31c741ab3 255 Pfam PF00005 ABC transporter 19 179 5.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS16000 fbf0fb23a62bbe067a03b5e31c741ab3 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 1.3E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS18315 cfdf3c7edd8efb7908eea1cf81f245eb 327 SUPERFAMILY SSF54427 205 325 1.14E-18 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS18315 cfdf3c7edd8efb7908eea1cf81f245eb 327 SMART SM00978 183 326 5.8E-32 T 06-07-2017 IPR007379 Tim44-like domain CAK95_RS18315 cfdf3c7edd8efb7908eea1cf81f245eb 327 Pfam PF04280 Tim44-like domain 201 325 5.9E-26 T 06-07-2017 IPR007379 Tim44-like domain CAK95_RS11870 aa84881ea8ee434c5fde5bd6c4ee6572 97 Pfam PF00839 Cysteine rich repeat 45 77 5.5E-5 T 06-07-2017 IPR001893 Cysteine-rich Golgi apparatus protein 1 repeat GO:0016020 Reactome: R-HSA-202733 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.4E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 SUPERFAMILY SSF46689 9 84 5.49E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 Gene3D G3DSA:1.10.357.10 61 208 3.2E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 Gene3D G3DSA:1.10.10.60 6 60 7.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 153 205 4.3E-6 T 06-07-2017 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS26270 0abfcfe3df50187fc351ccaaf71b3800 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS19210 9e1249a75e6a5743a0032c32026dc357 321 SUPERFAMILY SSF53850 89 284 5.43E-12 T 06-07-2017 CAK95_RS19210 9e1249a75e6a5743a0032c32026dc357 321 PIRSF PIRSF017082 2 321 1.6E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS19210 9e1249a75e6a5743a0032c32026dc357 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 317 7.6E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 Gene3D G3DSA:2.10.109.10 21 107 5.2E-38 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 Gene3D G3DSA:2.10.109.10 175 221 5.2E-38 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 ProSitePatterns PS00760 Signal peptidases I lysine active site. 99 111 - T 06-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 SUPERFAMILY SSF51306 24 245 1.34E-54 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 97 109 6.7E-24 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 175 194 6.7E-24 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 6.7E-24 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 Pfam PF00717 Peptidase S24-like 30 121 5.9E-18 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 ProSitePatterns PS00761 Signal peptidases I signature 3. 180 193 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAK95_RS05430 9ab773c3cc30c6968c24a1d46fcf4ed6 247 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 217 8.3E-44 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 PRINTS PR00502 NUDIX hydrolase family signature 42 56 2.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 PRINTS PR00502 NUDIX hydrolase family signature 56 71 2.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 Gene3D G3DSA:3.90.79.10 18 140 1.1E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 Pfam PF00293 NUDIX domain 18 125 1.8E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS15945 3fcbd3b560a3e33daf56d91a0edca7bb 148 SUPERFAMILY SSF55811 8 141 3.11E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS10405 d00a738c1410e23d01d8d94b9febec6b 248 Gene3D G3DSA:3.40.50.150 24 230 1.2E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10405 d00a738c1410e23d01d8d94b9febec6b 248 SUPERFAMILY SSF53335 15 244 2.37E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10405 d00a738c1410e23d01d8d94b9febec6b 248 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 11 247 40.118 T 06-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CAK95_RS10405 d00a738c1410e23d01d8d94b9febec6b 248 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 13 241 8.0E-89 T 06-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CAK95_RS10405 d00a738c1410e23d01d8d94b9febec6b 248 Pfam PF13489 Methyltransferase domain 64 217 2.7E-24 T 06-07-2017 CAK95_RS00715 2257d67443f5a116b0a829f85b85c7aa 289 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 62 284 1.0E-47 T 06-07-2017 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAK95_RS00715 2257d67443f5a116b0a829f85b85c7aa 289 Pfam PF02666 Phosphatidylserine decarboxylase 72 284 8.6E-53 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAK95_RS21775 446faad3daccd1bb78c043b17664fc3a 192 Pfam PF02592 Putative vitamin uptake transporter 101 179 5.1E-10 T 06-07-2017 IPR003744 Protein of unknown function DUF165 CAK95_RS18645 010494494d367a92f1a2799715cc9ee6 251 Gene3D G3DSA:3.40.50.300 4 246 4.7E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18645 010494494d367a92f1a2799715cc9ee6 251 Pfam PF00005 ABC transporter 23 178 3.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS18645 010494494d367a92f1a2799715cc9ee6 251 SMART SM00382 31 233 2.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS18645 010494494d367a92f1a2799715cc9ee6 251 SUPERFAMILY SSF52540 5 247 1.85E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18645 010494494d367a92f1a2799715cc9ee6 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.9E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS14290 4723639c5cf141e127f200a82af6b00d 320 PIRSF PIRSF017082 2 320 1.2E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14290 4723639c5cf141e127f200a82af6b00d 320 SUPERFAMILY SSF53850 107 280 5.74E-10 T 06-07-2017 CAK95_RS14290 4723639c5cf141e127f200a82af6b00d 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 2.2E-92 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18000 eeeb90b3e334ee6ac29da2b93d513029 652 Gene3D G3DSA:3.40.50.1110 254 522 2.2E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS18000 eeeb90b3e334ee6ac29da2b93d513029 652 Gene3D G3DSA:3.40.50.1110 191 202 2.2E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS18000 eeeb90b3e334ee6ac29da2b93d513029 652 Gene3D G3DSA:3.40.50.1110 592 626 2.2E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS18000 eeeb90b3e334ee6ac29da2b93d513029 652 SUPERFAMILY SSF52266 585 628 3.75E-11 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS18000 eeeb90b3e334ee6ac29da2b93d513029 652 SUPERFAMILY SSF52266 256 517 3.75E-11 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 SUPERFAMILY SSF46785 61 132 5.55E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 Gene3D G3DSA:1.10.10.10 60 133 2.8E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 Pfam PF01614 Bacterial transcriptional regulator 179 301 1.0E-29 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 Gene3D G3DSA:3.30.450.40 139 303 1.3E-51 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 SMART SM00346 59 149 2.2E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 Pfam PF09339 IclR helix-turn-helix domain 61 110 1.4E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS09380 697b75be9e1c4923b660f41a9002016d 305 SUPERFAMILY SSF55781 125 301 9.81E-47 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 Gene3D G3DSA:3.30.70.260 140 209 7.6E-22 T 06-07-2017 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 224 2.4E-56 T 06-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 226 1.3E-72 T 06-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 Gene3D G3DSA:3.40.50.1360 5 139 1.5E-53 T 06-07-2017 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 SUPERFAMILY SSF100950 2 144 1.67E-40 T 06-07-2017 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 229 32.634 T 06-07-2017 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAK95_RS19930 aa8f875ad80703dedba76ca886fd3e2e 232 SUPERFAMILY SSF75445 128 212 3.27E-19 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 327 3.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.2E-13 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.2E-13 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.2E-13 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 1.2E-13 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 Gene3D G3DSA:3.50.50.60 106 335 5.5E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 1.1E-9 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.1E-9 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 1.1E-9 T 06-07-2017 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 Gene3D G3DSA:3.50.50.60 9 105 1.1E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00865 a85e6c7b3de0bcf3931c8fe9e7d6398a 440 SUPERFAMILY SSF51905 11 341 9.79E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS28885 daedf00e4c78ed9a143f71dcaaebee0d 325 SUPERFAMILY SSF51556 1 325 1.13E-60 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS28885 daedf00e4c78ed9a143f71dcaaebee0d 325 Gene3D G3DSA:3.20.20.140 1 324 7.9E-64 T 06-07-2017 CAK95_RS28885 daedf00e4c78ed9a143f71dcaaebee0d 325 Pfam PF04909 Amidohydrolase 3 311 1.5E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS03580 6ab21eb9cf9f524585f2697a032eed5c 301 Pfam PF13289 SIR2-like domain 65 221 2.8E-24 T 06-07-2017 CAK95_RS27435 bcde65801e37a1402cb9acc0aecc7c4c 265 SUPERFAMILY SSF102198 22 263 1.44E-51 T 06-07-2017 CAK95_RS27435 bcde65801e37a1402cb9acc0aecc7c4c 265 Gene3D G3DSA:3.50.30.50 23 263 2.1E-56 T 06-07-2017 CAK95_RS27435 bcde65801e37a1402cb9acc0aecc7c4c 265 Pfam PF04199 Putative cyclase 26 202 1.2E-31 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS02435 1608230b0853635489f1eebc01f7acd2 415 Pfam PF01757 Acyltransferase family 65 378 3.8E-13 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK95_RS07255 22bcd897fc4fb70418168c115f2d17f8 134 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 3.2E-30 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07255 22bcd897fc4fb70418168c115f2d17f8 134 SUPERFAMILY SSF141091 1 100 8.24E-33 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07255 22bcd897fc4fb70418168c115f2d17f8 134 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.5E-34 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07255 22bcd897fc4fb70418168c115f2d17f8 134 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.113 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07255 22bcd897fc4fb70418168c115f2d17f8 134 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 Pfam PF13458 Periplasmic binding protein 26 371 2.1E-64 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 Gene3D G3DSA:3.40.50.2300 150 301 8.4E-20 T 06-07-2017 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 88 98 4.0E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 335 350 4.0E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 293 4.0E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 4.0E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 SUPERFAMILY SSF53822 26 374 6.54E-76 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 Gene3D G3DSA:3.40.50.2300 302 356 7.6E-34 T 06-07-2017 CAK95_RS00930 69da420934dc03ab3b316bc3c2b9481d 392 Gene3D G3DSA:3.40.50.2300 22 147 7.6E-34 T 06-07-2017 CAK95_RS02650 50cb930d0a637536daa5b5782f545438 320 PIRSF PIRSF037112 3 312 5.9E-109 T 06-07-2017 IPR017113 Antirestriction, ArdC CAK95_RS02650 50cb930d0a637536daa5b5782f545438 320 Pfam PF08401 Domain of unknown function (DUF1738) 17 139 1.1E-39 T 06-07-2017 IPR013610 Domain of unknown function DUF1738 CAK95_RS09570 75e08382cd2c2718766e54ef9001b2cc 431 Pfam PF13449 Esterase-like activity of phytase 112 411 2.4E-49 T 06-07-2017 IPR027372 Phytase-like domain CAK95_RS09570 75e08382cd2c2718766e54ef9001b2cc 431 Gene3D G3DSA:2.120.10.30 180 258 7.9E-5 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS09570 75e08382cd2c2718766e54ef9001b2cc 431 SUPERFAMILY SSF63825 180 255 1.99E-5 T 06-07-2017 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 PIRSF PIRSF001365 5 303 8.6E-78 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 11 294 2.3E-80 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 169 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 3.8E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 3.8E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 3.8E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.8E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 Pfam PF00701 Dihydrodipicolinate synthetase family 8 293 1.3E-72 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 SMART SM01130 7 296 2.6E-104 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 SUPERFAMILY SSF51569 5 298 3.87E-87 T 06-07-2017 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 294 47.107 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK95_RS28375 180e25c26ef509b1bf396d42ce2610e9 304 Gene3D G3DSA:3.20.20.70 7 298 2.6E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 97 117 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 42 59 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 59 79 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 118 138 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 153 179 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 201 225 4.5E-56 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 42 225 7.6E-83 T 06-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CAK95_RS07575 1d9c861495568f6628eb0d6829a907d2 244 Pfam PF01578 Cytochrome C assembly protein 26 181 4.9E-31 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAK95_RS00095 ec36a93aed959725cc07d233ed74049f 248 SUPERFAMILY SSF47616 119 242 1.03E-15 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS00095 ec36a93aed959725cc07d233ed74049f 248 Gene3D G3DSA:3.40.30.10 43 126 1.8E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS00095 ec36a93aed959725cc07d233ed74049f 248 Pfam PF02798 Glutathione S-transferase, N-terminal domain 50 111 2.7E-11 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS00095 ec36a93aed959725cc07d233ed74049f 248 Gene3D G3DSA:1.20.1050.10 127 232 2.2E-16 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS00095 ec36a93aed959725cc07d233ed74049f 248 SUPERFAMILY SSF52833 41 122 7.18E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS13105 37a921812535c6aa51c095b8128af412 453 SUPERFAMILY SSF75304 4 439 8.63E-124 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS13105 37a921812535c6aa51c095b8128af412 453 Pfam PF01425 Amidase 28 431 1.3E-93 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS13105 37a921812535c6aa51c095b8128af412 453 Gene3D G3DSA:3.90.1300.10 6 443 3.1E-133 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS13710 ecda3d6826ff6aa73a89cab5f42ef434 368 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 5 289 3.6E-84 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK95_RS13710 ecda3d6826ff6aa73a89cab5f42ef434 368 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 5 284 1.7E-53 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK95_RS13710 ecda3d6826ff6aa73a89cab5f42ef434 368 SUPERFAMILY SSF55931 3 363 8.34E-96 T 06-07-2017 CAK95_RS13710 ecda3d6826ff6aa73a89cab5f42ef434 368 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 368 80.598 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK95_RS00370 ac3c650bb563474a4e47151e25a976e7 112 Gene3D G3DSA:2.102.10.10 2 105 1.4E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00370 ac3c650bb563474a4e47151e25a976e7 112 Pfam PF00355 Rieske [2Fe-2S] domain 4 91 2.0E-14 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS00370 ac3c650bb563474a4e47151e25a976e7 112 SUPERFAMILY SSF50022 2 104 6.15E-25 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK95_RS16015 c4125f5c72d2a9d6fbefa4f915c4d4ce 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 273 2.4E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 PIRSF PIRSF002825 5 342 3.4E-101 T 06-07-2017 IPR026045 Ferric binding protein CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 SUPERFAMILY SSF53850 30 339 1.89E-83 T 06-07-2017 CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 Gene3D G3DSA:3.40.190.10 7 126 2.7E-34 T 06-07-2017 CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 Gene3D G3DSA:3.40.190.10 273 319 2.7E-34 T 06-07-2017 CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 Gene3D G3DSA:3.40.190.10 130 272 1.6E-54 T 06-07-2017 CAK95_RS12645 798bc0c6bd4ab62a627fb59631417be3 342 Pfam PF13343 Bacterial extracellular solute-binding protein 77 300 7.2E-31 T 06-07-2017 CAK95_RS19285 c92daebb1adf7d94211f98270b3655df 149 SUPERFAMILY SSF54637 11 134 1.95E-24 T 06-07-2017 IPR029069 HotDog domain CAK95_RS19285 c92daebb1adf7d94211f98270b3655df 149 Pfam PF03061 Thioesterase superfamily 51 124 6.3E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS19285 c92daebb1adf7d94211f98270b3655df 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 131 4.7E-17 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK95_RS19285 c92daebb1adf7d94211f98270b3655df 149 Gene3D G3DSA:3.10.129.10 5 134 6.1E-28 T 06-07-2017 IPR029069 HotDog domain CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 Gene3D G3DSA:3.10.20.30 2 77 1.4E-24 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 Gene3D G3DSA:1.10.150.120 78 153 8.3E-34 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 SUPERFAMILY SSF54292 2 90 1.23E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 SUPERFAMILY SSF47741 87 154 7.85E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 Pfam PF01799 [2Fe-2S] binding domain 76 148 3.4E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK95_RS04925 50ad1548841616370fddef046d1cab75 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 65 8.3E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12675 c7d3fe8c5d01f5297d2570ea36dd044c 223 Gene3D G3DSA:3.90.850.10 4 220 7.1E-33 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS12675 c7d3fe8c5d01f5297d2570ea36dd044c 223 SUPERFAMILY SSF56529 3 220 1.06E-30 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17730 505b2a5c9b4d6a17ec492b14cb713db6 640 Pfam PF01757 Acyltransferase family 5 328 9.5E-29 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK95_RS05635 5ce9fe0fdebba8876b210cf7f3be157c 245 Pfam PF00149 Calcineurin-like phosphoesterase 47 160 4.5E-6 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK95_RS05635 5ce9fe0fdebba8876b210cf7f3be157c 245 Gene3D G3DSA:3.60.21.10 47 137 2.3E-10 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS05635 5ce9fe0fdebba8876b210cf7f3be157c 245 SUPERFAMILY SSF56300 47 136 9.19E-15 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK95_RS05635 5ce9fe0fdebba8876b210cf7f3be157c 245 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 27 219 4.6E-66 T 06-07-2017 IPR026336 Metallophosphoesterase, DNA ligase-associated CAK95_RS25310 f68994327dcc2e04808cf501f93393ea 422 Pfam PF07690 Major Facilitator Superfamily 41 338 6.4E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS25310 f68994327dcc2e04808cf501f93393ea 422 SUPERFAMILY SSF103473 29 412 3.01E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS25310 f68994327dcc2e04808cf501f93393ea 422 Gene3D G3DSA:1.20.1250.20 245 412 1.3E-8 T 06-07-2017 CAK95_RS25310 f68994327dcc2e04808cf501f93393ea 422 Gene3D G3DSA:1.20.1250.20 40 213 3.2E-17 T 06-07-2017 CAK95_RS24690 80f44081830038e6bcc12954b725d33a 176 Pfam PF06073 Bacterial protein of unknown function (DUF934) 51 154 4.4E-38 T 06-07-2017 IPR008318 Uncharacterised conserved protein UCP030820 CAK95_RS24690 80f44081830038e6bcc12954b725d33a 176 PIRSF PIRSF030820 3 164 9.8E-51 T 06-07-2017 IPR008318 Uncharacterised conserved protein UCP030820 CAK95_RS28370 88275c754539f3ff38441ada2d0620d8 285 SUPERFAMILY SSF56529 61 281 3.92E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS28370 88275c754539f3ff38441ada2d0620d8 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 281 3.1E-62 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS28370 88275c754539f3ff38441ada2d0620d8 285 Gene3D G3DSA:3.90.850.10 65 282 1.6E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS02370 07a100377c61d37687afb12692faaa27 199 Gene3D G3DSA:1.20.950.20 10 74 1.1E-6 T 06-07-2017 CAK95_RS02370 07a100377c61d37687afb12692faaa27 199 SUPERFAMILY SSF81342 9 186 1.1E-24 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK95_RS02370 07a100377c61d37687afb12692faaa27 199 Pfam PF01292 Prokaryotic cytochrome b561 11 183 1.9E-21 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAK95_RS12875 c5932f6cb004239eb3788f96ae4b494e 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAK95_RS12875 c5932f6cb004239eb3788f96ae4b494e 308 SUPERFAMILY SSF53613 6 301 1.56E-74 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS12875 c5932f6cb004239eb3788f96ae4b494e 308 Pfam PF00294 pfkB family carbohydrate kinase 6 300 1.8E-49 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK95_RS12875 c5932f6cb004239eb3788f96ae4b494e 308 Gene3D G3DSA:3.40.1190.20 3 304 6.4E-72 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS15670 e413580ad277fac2a8022b13991cf742 168 SUPERFAMILY SSF52799 54 140 1.84E-13 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAK95_RS15670 e413580ad277fac2a8022b13991cf742 168 Pfam PF00102 Protein-tyrosine phosphatase 58 108 1.5E-5 T 06-07-2017 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 CAK95_RS15670 e413580ad277fac2a8022b13991cf742 168 Gene3D G3DSA:3.90.190.10 12 120 4.8E-10 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAK95_RS16450 6ed1f572f97c179b4985fc60b9611474 132 Gene3D G3DSA:1.10.10.10 11 128 1.1E-46 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16450 6ed1f572f97c179b4985fc60b9611474 132 SUPERFAMILY SSF46785 16 127 2.93E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16450 6ed1f572f97c179b4985fc60b9611474 132 Pfam PF01638 HxlR-like helix-turn-helix 31 117 7.3E-27 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK95_RS10670 2fac67bcc1d9492053f4da3472e320c4 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 247 1.2E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10670 2fac67bcc1d9492053f4da3472e320c4 255 SUPERFAMILY SSF161098 54 233 2.62E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10670 2fac67bcc1d9492053f4da3472e320c4 255 Gene3D G3DSA:1.10.3720.10 53 244 1.5E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28430 374db39b892328529e065a13c2070b56 234 Pfam PF04402 Protein of unknown function (DUF541) 31 228 1.2E-31 T 06-07-2017 IPR007497 Protein of unknown function DUF541 CAK95_RS04365 657c4ad67e73f1ab4638bc0414580507 68 Pfam PF04325 Protein of unknown function (DUF465) 13 58 2.5E-15 T 06-07-2017 IPR007420 Protein of unknown function DUF465 CAK95_RS22500 53c8c495d8a0d5b042bc69c9466a51df 179 Pfam PF03981 Ubiquinol-cytochrome C chaperone 34 170 1.7E-34 T 06-07-2017 IPR021150 Ubiquinol-cytochrome c chaperone/UPF0174 CAK95_RS22500 53c8c495d8a0d5b042bc69c9466a51df 179 PIRSF PIRSF032079 1 175 1.2E-53 T 06-07-2017 IPR014569 Ubiquinol-cytochrome c chaperone, CBP3-related CAK95_RS04600 36fb22fea117777f194e18932f35558a 156 Pfam PF07883 Cupin domain 57 124 3.9E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS04600 36fb22fea117777f194e18932f35558a 156 SUPERFAMILY SSF51182 19 126 6.11E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS04600 36fb22fea117777f194e18932f35558a 156 Gene3D G3DSA:2.60.120.10 18 129 3.7E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 SUPERFAMILY SSF53901 7 112 3.22E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 SUPERFAMILY SSF53901 173 346 3.22E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Gene3D G3DSA:3.40.47.10 164 226 8.7E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Gene3D G3DSA:3.40.47.10 6 112 8.7E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Gene3D G3DSA:3.40.47.10 140 163 3.6E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Gene3D G3DSA:3.40.47.10 232 354 3.6E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 PIRSF PIRSF000429 2 373 3.0E-56 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Pfam PF02803 Thiolase, C-terminal domain 242 344 6.9E-9 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK95_RS03295 8c69d0fe956b1a30c13f322ca0cb4017 377 Pfam PF00108 Thiolase, N-terminal domain 6 178 4.3E-22 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 Pfam PF00005 ABC transporter 336 469 4.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 Pfam PF00005 ABC transporter 24 187 1.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 Gene3D G3DSA:3.40.50.300 318 530 4.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 5 549 9.5E-289 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 SUPERFAMILY SSF52540 10 240 1.14E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 Pfam PF12848 ABC transporter 226 293 7.5E-11 T 06-07-2017 IPR032781 ABC-transporter extension domain CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 SUPERFAMILY SSF52540 300 518 6.38E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 Gene3D G3DSA:3.40.50.300 10 283 4.8E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 SMART SM00382 344 520 1.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS01990 5fda984c98a6dab307bd8f82b068d679 551 SMART SM00382 33 228 2.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 Pfam PF01252 Signal peptidase (SPase) II 19 163 8.3E-31 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 TIGRFAM TIGR00077 lspA: signal peptidase II 19 168 2.3E-31 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 ProSitePatterns PS00855 Signal peptidases II signature. 107 119 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 169 14.498 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 144 160 8.0E-14 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 58 66 8.0E-14 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS13310 c0ff439f996dd116bd6f03ac16e9e909 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 104 119 8.0E-14 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK95_RS11200 5acca7181e508948e11a641aa9219019 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 128 1.1E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS11200 5acca7181e508948e11a641aa9219019 146 SUPERFAMILY SSF54593 5 142 7.65E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS11200 5acca7181e508948e11a641aa9219019 146 Gene3D G3DSA:3.10.180.10 1 143 2.0E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 SUPERFAMILY SSF53383 24 422 1.13E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 Gene3D G3DSA:3.40.640.10 88 326 2.4E-49 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 Gene3D G3DSA:3.90.1150.10 18 87 2.9E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 Gene3D G3DSA:3.90.1150.10 329 423 2.9E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 Pfam PF00202 Aminotransferase class-III 197 352 1.1E-23 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS20485 0478bec578863c0ca7f6821fe74675b7 458 Pfam PF00202 Aminotransferase class-III 52 148 8.1E-13 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK95_RS03220 a78fa908f030d868a9c4d15ccffea378 269 Gene3D G3DSA:1.20.141.10 2 169 1.7E-46 T 06-07-2017 CAK95_RS03220 a78fa908f030d868a9c4d15ccffea378 269 Pfam PF05838 Glycosyl hydrolase 108 10 93 2.4E-28 T 06-07-2017 IPR008565 Protein of unknown function DUF847 CAK95_RS03220 a78fa908f030d868a9c4d15ccffea378 269 SUPERFAMILY SSF53955 2 165 9.0E-42 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 Pfam PF00072 Response regulator receiver domain 18 127 2.3E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 SMART SM00448 16 127 1.6E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 Gene3D G3DSA:3.40.50.2300 16 156 2.6E-33 T 06-07-2017 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 SMART SM00421 151 208 1.0E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 SUPERFAMILY SSF46894 144 212 1.36E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 6.0E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 SUPERFAMILY SSF52172 15 165 2.42E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 Gene3D G3DSA:1.10.10.10 157 209 4.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS15470 0fd5cb18cdf50f11c184636c62f056bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS12450 ee9bb4d4a5572ba67fefec1b413a3cbd 81 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 26 34 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK95_RS12450 ee9bb4d4a5572ba67fefec1b413a3cbd 81 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 73 1.1E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS12450 ee9bb4d4a5572ba67fefec1b413a3cbd 81 Gene3D G3DSA:3.10.20.30 4 80 2.9E-18 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS12450 ee9bb4d4a5572ba67fefec1b413a3cbd 81 SUPERFAMILY SSF54292 3 80 1.44E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS16600 39617b1e11b3c907837878c36e926d77 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 278 1.2E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS19975 baa18793e7ef59ff8edebb7d7ff570d2 305 Pfam PF00892 EamA-like transporter family 9 141 1.2E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS19975 baa18793e7ef59ff8edebb7d7ff570d2 305 Pfam PF00892 EamA-like transporter family 151 280 7.7E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS19975 baa18793e7ef59ff8edebb7d7ff570d2 305 SUPERFAMILY SSF103481 203 284 2.88E-11 T 06-07-2017 CAK95_RS19975 baa18793e7ef59ff8edebb7d7ff570d2 305 SUPERFAMILY SSF103481 50 145 9.42E-13 T 06-07-2017 CAK95_RS03635 2cac7dff82e9f4db127a2188ca2403b7 146 Pfam PF11149 Protein of unknown function (DUF2924) 7 140 1.0E-50 T 06-07-2017 IPR021322 Protein of unknown function DUF2924 CAK95_RS08095 5e87fc391eae0550a5ea44f6041fb9d2 450 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 20 117 9.1E-7 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS08095 5e87fc391eae0550a5ea44f6041fb9d2 450 SUPERFAMILY SSF51735 17 142 6.47E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08095 5e87fc391eae0550a5ea44f6041fb9d2 450 SMART SM00858 353 418 8.4E-6 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS08095 5e87fc391eae0550a5ea44f6041fb9d2 450 Gene3D G3DSA:3.40.50.720 16 166 2.6E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08095 5e87fc391eae0550a5ea44f6041fb9d2 450 Pfam PF08666 SAF domain 353 418 1.3E-4 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK95_RS06980 6fe01bef139943d45b48836093b3d772 231 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 13 223 8.2E-69 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CAK95_RS06980 6fe01bef139943d45b48836093b3d772 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 225 1.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06980 6fe01bef139943d45b48836093b3d772 231 SUPERFAMILY SSF161098 6 215 3.66E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06980 6fe01bef139943d45b48836093b3d772 231 Gene3D G3DSA:1.10.3720.10 9 225 1.7E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS20260 303e39d68e33d29e1ebb6699c0c657db 265 Pfam PF13847 Methyltransferase domain 76 169 4.2E-7 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS20260 303e39d68e33d29e1ebb6699c0c657db 265 Gene3D G3DSA:3.40.50.150 76 242 4.4E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS20260 303e39d68e33d29e1ebb6699c0c657db 265 SUPERFAMILY SSF53335 73 244 1.84E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06620 55a185e4d4d6f3383f7ec5ebaab44d53 190 Pfam PF07811 TadE-like protein 30 71 2.6E-9 T 06-07-2017 IPR012495 TadE-like CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 SUPERFAMILY SSF56176 2 173 7.63E-46 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 SUPERFAMILY SSF55447 180 285 3.66E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 Gene3D G3DSA:3.30.390.50 178 287 1.5E-24 T 06-07-2017 CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 SMART SM01092 180 282 6.7E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 Gene3D G3DSA:3.30.465.10 58 172 3.6E-28 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 173 8.6E-41 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 180 281 2.0E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAK95_RS28590 fe0bba294c03be6ebc710a29cfb3f90c 292 Gene3D G3DSA:3.30.43.10 1 53 4.0E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS19090 05da6ffbb3012c265db2e28067a8f7fa 1295 Pfam PF13550 Putative phage tail protein 786 947 1.3E-45 T 06-07-2017 IPR032876 Tip attachment protein J CAK95_RS19090 05da6ffbb3012c265db2e28067a8f7fa 1295 Pfam PF13547 GTA TIM-barrel-like domain 431 728 1.7E-137 T 06-07-2017 IPR025195 GTA TIM-barrel-like domain CAK95_RS19090 05da6ffbb3012c265db2e28067a8f7fa 1295 SUPERFAMILY SSF51445 625 742 1.11E-9 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS19090 05da6ffbb3012c265db2e28067a8f7fa 1295 SUPERFAMILY SSF51445 326 402 1.11E-9 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS19090 05da6ffbb3012c265db2e28067a8f7fa 1295 SUPERFAMILY SSF51445 431 538 1.11E-9 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK95_RS04340 e38ec2c9d4cc0a4f32f4f49748a07307 383 SUPERFAMILY SSF53756 7 369 9.42E-67 T 06-07-2017 CAK95_RS04340 e38ec2c9d4cc0a4f32f4f49748a07307 383 Gene3D G3DSA:3.40.50.2000 173 344 3.0E-21 T 06-07-2017 CAK95_RS04340 e38ec2c9d4cc0a4f32f4f49748a07307 383 Pfam PF00534 Glycosyl transferases group 1 184 341 7.4E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS04340 e38ec2c9d4cc0a4f32f4f49748a07307 383 Pfam PF13439 Glycosyltransferase Family 4 13 183 1.5E-21 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS10355 2c430c5697c531841df787893ebf79cd 325 Pfam PF01699 Sodium/calcium exchanger protein 187 323 2.6E-27 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK95_RS10355 2c430c5697c531841df787893ebf79cd 325 Pfam PF01699 Sodium/calcium exchanger protein 4 141 1.4E-21 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK95_RS10355 2c430c5697c531841df787893ebf79cd 325 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 318 1.2E-68 T 06-07-2017 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 SUPERFAMILY SSF47616 141 261 4.73E-37 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 Gene3D G3DSA:1.20.1050.10 142 258 2.0E-52 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 Gene3D G3DSA:3.40.30.10 54 141 8.7E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 Pfam PF00043 Glutathione S-transferase, C-terminal domain 169 254 1.8E-9 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 Pfam PF02798 Glutathione S-transferase, N-terminal domain 64 139 2.4E-12 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS23775 cd30e7036d4880e602eaa60b9e764550 289 SUPERFAMILY SSF52833 59 142 5.49E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 SUPERFAMILY SSF53720 21 493 9.29E-164 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 25 504 8.1E-241 T 06-07-2017 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 Gene3D G3DSA:3.40.605.10 24 280 5.4E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 Pfam PF00171 Aldehyde dehydrogenase family 37 491 1.6E-172 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS28385 ff84c7da53e5ecf93d2505610dd4a986 506 Gene3D G3DSA:3.40.309.10 281 466 1.2E-69 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 54 100 7.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 Gene3D G3DSA:1.10.357.10 37 227 2.3E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 Pfam PF16859 Bacterial transcriptional repressor C-terminal 134 221 4.3E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 SUPERFAMILY SSF48498 132 234 1.19E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 75 98 2.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 67 2.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS20420 2a75b3f822bad38d49f7859f2ebb568f 239 SUPERFAMILY SSF46689 43 119 4.34E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 Gene3D G3DSA:3.20.20.30 348 435 1.3E-141 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 Gene3D G3DSA:3.20.20.30 2 310 1.3E-141 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 PIRSF PIRSF000337 3 443 7.3E-163 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 429 9.6E-172 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 SUPERFAMILY SSF51679 4 435 6.8E-138 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS16935 b1b252ab05a806c2eff5edfe9ac05995 455 Pfam PF00296 Luciferase-like monooxygenase 23 386 1.4E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 354 369 9.5E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 36 52 9.5E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 58 74 9.5E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 77 95 9.5E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 Pfam PF13458 Periplasmic binding protein 35 373 4.5E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 SUPERFAMILY SSF53822 35 387 6.8E-68 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS00340 b2542c1670c04e1ccbe59f1d5aedbb92 423 Gene3D G3DSA:3.40.50.2300 34 238 4.0E-45 T 06-07-2017 CAK95_RS06925 d9e842a8dd2d6d09884b7ab205e7f9f7 302 Pfam PF07751 Abi-like protein 17 216 2.7E-52 T 06-07-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like CAK95_RS06925 d9e842a8dd2d6d09884b7ab205e7f9f7 302 PIRSF PIRSF034934 1 302 3.6E-59 T 06-07-2017 IPR017034 Abortive infection system protein AbiD/AbiF CAK95_RS23550 ce01b6aafc252e11ac91fc02f7b35ecf 246 Pfam PF03741 Integral membrane protein TerC family 16 204 6.5E-48 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK95_RS20015 c9caf6d32cab2c39441efd9f7f5512bd 316 SMART SM00849 33 219 2.0E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20015 c9caf6d32cab2c39441efd9f7f5512bd 316 Gene3D G3DSA:3.60.15.10 11 246 5.7E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20015 c9caf6d32cab2c39441efd9f7f5512bd 316 SUPERFAMILY SSF56281 15 307 3.92E-54 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20015 c9caf6d32cab2c39441efd9f7f5512bd 316 Pfam PF00753 Metallo-beta-lactamase superfamily 33 186 2.9E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS02065 4b8b53a3b4d5e7f98a14c733489bb602 170 Gene3D G3DSA:3.40.50.1820 11 80 2.4E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS02065 4b8b53a3b4d5e7f98a14c733489bb602 170 SUPERFAMILY SSF53474 9 114 2.8E-10 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS02065 4b8b53a3b4d5e7f98a14c733489bb602 170 Gene3D G3DSA:3.40.50.1820 81 138 1.6E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 2.5E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 74 2.5E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 42 58 2.5E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 Gene3D G3DSA:1.10.10.10 2 133 8.2E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 SMART SM00347 18 118 1.8E-24 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 SUPERFAMILY SSF46785 2 136 6.84E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10240 2129abf23e14c472f4529cb4ed88b43c 152 Pfam PF01047 MarR family 26 82 5.4E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 Gene3D G3DSA:1.10.10.10 8 71 1.2E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 Gene3D G3DSA:3.30.450.40 92 257 2.8E-33 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 Pfam PF01614 Bacterial transcriptional regulator 142 242 1.6E-17 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 SUPERFAMILY SSF46785 22 90 1.09E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 Pfam PF09339 IclR helix-turn-helix domain 22 69 1.2E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 SUPERFAMILY SSF55781 92 257 6.02E-28 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS06405 bc9ecbd664a510f72c551e52d3ae805d 261 SMART SM00346 19 109 0.0028 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 Pfam PF00571 CBS domain 12 58 2.8E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 Pfam PF00571 CBS domain 73 123 1.8E-12 T 06-07-2017 IPR000644 CBS domain CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 SMART SM00116 79 126 2.0E-9 T 06-07-2017 IPR000644 CBS domain CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 SMART SM00116 13 61 2.6E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 Gene3D G3DSA:3.10.580.10 1 124 3.1E-34 T 06-07-2017 CAK95_RS20755 076691bc587a324d1c39816fae75bb66 143 SUPERFAMILY SSF54631 1 141 9.22E-35 T 06-07-2017 CAK95_RS14185 e8c1ced5566898c6dc7e8f6bdc34e9fb 237 Gene3D G3DSA:3.40.50.850 30 229 3.6E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS14185 e8c1ced5566898c6dc7e8f6bdc34e9fb 237 Pfam PF00857 Isochorismatase family 36 218 1.1E-30 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS14185 e8c1ced5566898c6dc7e8f6bdc34e9fb 237 SUPERFAMILY SSF52499 25 225 1.44E-43 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS11405 4f80372d56661533dae300026414ae0e 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 236 4.9E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11405 4f80372d56661533dae300026414ae0e 258 Gene3D G3DSA:1.10.3720.10 52 240 2.0E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11405 4f80372d56661533dae300026414ae0e 258 SUPERFAMILY SSF161098 53 240 1.7E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05415 53bcb6c6ee381c6273d058d90b9651f8 174 Gene3D G3DSA:3.50.4.10 109 172 3.9E-9 T 06-07-2017 CAK95_RS05415 53bcb6c6ee381c6273d058d90b9651f8 174 Gene3D G3DSA:3.50.4.10 16 89 1.3E-9 T 06-07-2017 CAK95_RS05415 53bcb6c6ee381c6273d058d90b9651f8 174 Pfam PF14295 PAN domain 22 72 3.6E-14 T 06-07-2017 IPR003609 PAN/Apple domain CAK95_RS05415 53bcb6c6ee381c6273d058d90b9651f8 174 Pfam PF14295 PAN domain 105 156 4.3E-13 T 06-07-2017 IPR003609 PAN/Apple domain CAK95_RS13195 943380a4cef5d6b281e6892234f1ec9a 256 Gene3D G3DSA:2.40.440.10 124 255 9.6E-37 T 06-07-2017 CAK95_RS13195 943380a4cef5d6b281e6892234f1ec9a 256 Pfam PF03734 L,D-transpeptidase catalytic domain 128 255 6.2E-19 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS13195 943380a4cef5d6b281e6892234f1ec9a 256 SUPERFAMILY SSF141523 122 256 9.55E-35 T 06-07-2017 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 66 127 5.5E-8 T 06-07-2017 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 487 4.7E-196 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 6.3E-50 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 6.3E-50 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 6.3E-50 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 6.3E-50 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 6.3E-50 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22890 84507ea8f8aa193ab34d8aadc9cc5385 514 Pfam PF00361 Proton-conducting membrane transporter 133 420 1.6E-89 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS22525 9e782013eeceb8b63fd240ae365bcbf5 187 SMART SM00422 10 79 1.2E-4 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS22525 9e782013eeceb8b63fd240ae365bcbf5 187 Gene3D G3DSA:1.10.1660.10 139 174 1.1E-13 T 06-07-2017 CAK95_RS22525 9e782013eeceb8b63fd240ae365bcbf5 187 Gene3D G3DSA:1.10.1660.10 10 80 1.1E-13 T 06-07-2017 CAK95_RS22525 9e782013eeceb8b63fd240ae365bcbf5 187 SUPERFAMILY SSF46955 10 77 1.24E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK95_RS22525 9e782013eeceb8b63fd240ae365bcbf5 187 Pfam PF13411 MerR HTH family regulatory protein 10 78 1.8E-23 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 SUPERFAMILY SSF50891 16 164 4.53E-48 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 60 1.3E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 127 139 1.3E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 71 83 1.3E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 140 155 1.3E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 32 172 6.4E-46 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 66 83 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CAK95_RS22260 1238be0d5373a9be53ad02569e55e2bb 181 Gene3D G3DSA:2.40.100.10 18 173 4.9E-48 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK95_RS06245 8255b1279409b96accb9392a71f59dde 339 SUPERFAMILY SSF51556 1 332 6.5E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS06245 8255b1279409b96accb9392a71f59dde 339 Gene3D G3DSA:3.20.20.140 1 334 4.1E-67 T 06-07-2017 CAK95_RS06245 8255b1279409b96accb9392a71f59dde 339 Pfam PF04909 Amidohydrolase 81 329 2.1E-32 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS27140 c56a018b3f3975defa4cf9b094b4862f 113 Pfam PF13564 DoxX-like family 11 105 9.3E-10 T 06-07-2017 IPR032808 DoxX family CAK95_RS17710 a7800cb18918ac374c1f773240a45736 390 SUPERFAMILY SSF53756 15 381 1.36E-64 T 06-07-2017 CAK95_RS17710 a7800cb18918ac374c1f773240a45736 390 Gene3D G3DSA:3.40.50.2000 178 361 3.6E-25 T 06-07-2017 CAK95_RS17710 a7800cb18918ac374c1f773240a45736 390 Pfam PF13439 Glycosyltransferase Family 4 25 186 1.5E-12 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS17710 a7800cb18918ac374c1f773240a45736 390 Pfam PF13692 Glycosyl transferases group 1 213 346 1.5E-24 T 06-07-2017 CAK95_RS12065 101705573a2b20869ad5686d62f24d98 220 ProSitePatterns PS00194 Thioredoxin family active site. 103 121 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS12065 101705573a2b20869ad5686d62f24d98 220 Gene3D G3DSA:3.40.30.10 27 219 7.4E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12065 101705573a2b20869ad5686d62f24d98 220 Pfam PF08534 Redoxin 83 205 6.2E-21 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK95_RS12065 101705573a2b20869ad5686d62f24d98 220 SUPERFAMILY SSF52833 69 218 1.01E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10695 e717dead84fbc9ec5eab6b978d0ae8ca 250 Pfam PF00005 ABC transporter 21 177 1.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS10695 e717dead84fbc9ec5eab6b978d0ae8ca 250 Gene3D G3DSA:3.40.50.300 3 243 2.7E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10695 e717dead84fbc9ec5eab6b978d0ae8ca 250 SUPERFAMILY SSF52540 3 246 2.39E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS10695 e717dead84fbc9ec5eab6b978d0ae8ca 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.0E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS10695 e717dead84fbc9ec5eab6b978d0ae8ca 250 SMART SM00382 30 224 6.5E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS04030 e862aacbbce7a58ff8c7de28bce2004a 155 Gene3D G3DSA:3.10.450.50 10 150 4.1E-72 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS04030 e862aacbbce7a58ff8c7de28bce2004a 155 Pfam PF07080 Protein of unknown function (DUF1348) 3 145 1.0E-72 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 CAK95_RS04030 e862aacbbce7a58ff8c7de28bce2004a 155 SUPERFAMILY SSF54427 2 150 3.73E-75 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 Gene3D G3DSA:3.40.50.2300 4 127 2.4E-18 T 06-07-2017 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 206 1.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 Gene3D G3DSA:1.10.10.10 148 210 3.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 SMART SM00448 2 116 4.9E-4 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 SUPERFAMILY SSF46894 148 211 5.44E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 SMART SM00421 152 209 1.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 SUPERFAMILY SSF52172 4 130 1.85E-16 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS10780 7bc4b257891cccd952771691d38060a7 238 Pfam PF00072 Response regulator receiver domain 4 116 5.4E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS02715 20274fb12bc9280f68171cb7d047185e 158 Pfam PF14437 MafB19-like deaminase 3 108 3.5E-18 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAK95_RS02715 20274fb12bc9280f68171cb7d047185e 158 SUPERFAMILY SSF53927 2 151 2.83E-32 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS02715 20274fb12bc9280f68171cb7d047185e 158 Gene3D G3DSA:3.40.140.10 1 151 3.8E-35 T 06-07-2017 CAK95_RS00900 f256ca268d49cd629cd3a3976e2a47d4 609 Gene3D G3DSA:1.50.10.10 220 598 4.6E-82 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK95_RS00900 f256ca268d49cd629cd3a3976e2a47d4 609 Pfam PF00723 Glycosyl hydrolases family 15 228 588 7.3E-65 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK95_RS00900 f256ca268d49cd629cd3a3976e2a47d4 609 SUPERFAMILY SSF48208 211 590 2.19E-104 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK95_RS28855 996c9a1fc60fc2a1294886d819c91fe0 247 Gene3D G3DSA:3.40.50.300 5 215 6.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28855 996c9a1fc60fc2a1294886d819c91fe0 247 SUPERFAMILY SSF52540 9 226 2.42E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28855 996c9a1fc60fc2a1294886d819c91fe0 247 Pfam PF00005 ABC transporter 25 167 1.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28855 996c9a1fc60fc2a1294886d819c91fe0 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS28855 996c9a1fc60fc2a1294886d819c91fe0 247 SMART SM00382 33 217 1.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS23370 1e176f51c680f1fb79523d70bcf046d7 113 SMART SM00507 21 73 5.5E-9 T 06-07-2017 IPR003615 HNH nuclease CAK95_RS23370 1e176f51c680f1fb79523d70bcf046d7 113 Pfam PF01844 HNH endonuclease 34 77 1.8E-8 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CAK95_RS13775 724e3ce783975be356f51c435ec88c69 436 PIRSF PIRSF006066 7 436 1.4E-94 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS13775 724e3ce783975be356f51c435ec88c69 436 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 426 1.1E-93 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS13775 724e3ce783975be356f51c435ec88c69 436 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 24 431 8.4E-95 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAK95_RS28790 8cf46f70d7c865a98c2adbc651d6355e 662 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 133 569 5.3E-88 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS28790 8cf46f70d7c865a98c2adbc651d6355e 662 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 47 643 2.9E-167 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein CAK95_RS28220 b23213be40bffec1efbb12f0de59090a 286 SUPERFAMILY SSF103481 42 134 1.09E-13 T 06-07-2017 CAK95_RS28220 b23213be40bffec1efbb12f0de59090a 286 Pfam PF00892 EamA-like transporter family 142 277 2.6E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS28220 b23213be40bffec1efbb12f0de59090a 286 Pfam PF00892 EamA-like transporter family 6 130 1.6E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS28220 b23213be40bffec1efbb12f0de59090a 286 SUPERFAMILY SSF103481 186 282 3.01E-14 T 06-07-2017 CAK95_RS25770 4f7cd6a39fa63518f5237ea2a59ccd5d 266 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 19 205 1.1E-57 T 06-07-2017 IPR022301 Integral membrane protein YjbE CAK95_RS25770 4f7cd6a39fa63518f5237ea2a59ccd5d 266 Pfam PF03741 Integral membrane protein TerC family 21 204 2.6E-37 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK95_RS09005 e2bf3a8f5cf90ba1e0f5dc46df08d01c 315 Pfam PF00753 Metallo-beta-lactamase superfamily 85 275 3.0E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09005 e2bf3a8f5cf90ba1e0f5dc46df08d01c 315 Gene3D G3DSA:3.60.15.10 28 314 4.6E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09005 e2bf3a8f5cf90ba1e0f5dc46df08d01c 315 SMART SM00849 83 290 5.5E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09005 e2bf3a8f5cf90ba1e0f5dc46df08d01c 315 SUPERFAMILY SSF56281 30 312 2.75E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Gene3D G3DSA:1.25.40.10 45 286 3.4E-61 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 109 142 1.4E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 253 278 8.5E-4 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 144 179 3.9E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 72 107 1.6E-8 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 181 215 1.5E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 Pfam PF08238 Sel1 repeat 217 250 0.13 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SUPERFAMILY SSF81901 45 287 1.18E-48 T 06-07-2017 CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 72 107 5.3E-10 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 108 143 0.027 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 252 289 2.7 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 180 215 1.7E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 216 251 0.017 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS04180 9151ba0ab518059ae5facca517e94f07 323 SMART SM00671 144 179 2.7E-6 T 06-07-2017 IPR006597 Sel1-like repeat CAK95_RS26710 cffb5bc9a4d9aea7b281a94e95383abc 295 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 55 8.7E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAK95_RS26710 cffb5bc9a4d9aea7b281a94e95383abc 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 291 1.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26710 cffb5bc9a4d9aea7b281a94e95383abc 295 Gene3D G3DSA:1.10.3720.10 87 292 6.6E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26710 cffb5bc9a4d9aea7b281a94e95383abc 295 SUPERFAMILY SSF161098 90 277 3.49E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14975 cb594ea9e9d597cb1d5f9107e5c0400c 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 261 3.5E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS14975 cb594ea9e9d597cb1d5f9107e5c0400c 267 Gene3D G3DSA:3.90.226.10 13 259 7.4E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS14975 cb594ea9e9d597cb1d5f9107e5c0400c 267 SUPERFAMILY SSF52096 14 263 4.98E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS14975 cb594ea9e9d597cb1d5f9107e5c0400c 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS09610 96b0eebbe7279b7258ced0125af949f5 149 Gene3D G3DSA:1.10.10.10 3 144 8.2E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09610 96b0eebbe7279b7258ced0125af949f5 149 SMART SM00347 30 131 3.9E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09610 96b0eebbe7279b7258ced0125af949f5 149 SUPERFAMILY SSF46785 2 143 1.44E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09610 96b0eebbe7279b7258ced0125af949f5 149 Pfam PF01047 MarR family 39 87 3.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS10315 b50edb8d1f28a22ad5101533df91ee84 62 Pfam PF01783 Ribosomal L32p protein family 2 56 2.5E-21 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS10315 b50edb8d1f28a22ad5101533df91ee84 62 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 18.4 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS10315 b50edb8d1f28a22ad5101533df91ee84 62 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 4.1E-22 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS10315 b50edb8d1f28a22ad5101533df91ee84 62 SUPERFAMILY SSF57829 1 57 5.43E-20 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAK95_RS06935 d7b7867c0bba4f970476fe543ba7f5fb 71 SUPERFAMILY SSF160113 1 57 5.49E-17 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 CAK95_RS06935 d7b7867c0bba4f970476fe543ba7f5fb 71 Gene3D G3DSA:3.30.160.160 5 49 1.2E-17 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 CAK95_RS06935 d7b7867c0bba4f970476fe543ba7f5fb 71 Pfam PF07411 Domain of unknown function (DUF1508) 10 57 1.7E-18 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 11 326 1.0E-103 T 06-07-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 SUPERFAMILY SSF51735 138 293 1.54E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 131 1.8E-32 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 Gene3D G3DSA:3.90.180.10 1 165 4.3E-54 T 06-07-2017 IPR011032 GroES-like CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 SUPERFAMILY SSF50129 1 160 3.2E-47 T 06-07-2017 IPR011032 GroES-like CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 SMART SM00829 10 325 0.0031 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK95_RS27335 3a04559deb00b2228dea3b39021d3323 327 Gene3D G3DSA:3.40.50.720 166 295 3.8E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 7.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 7.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 7.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 SUPERFAMILY SSF46785 2 85 9.54E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 Gene3D G3DSA:3.40.190.10 181 262 7.2E-16 T 06-07-2017 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 Pfam PF03466 LysR substrate binding domain 86 291 2.7E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 Gene3D G3DSA:3.40.190.10 87 180 5.1E-14 T 06-07-2017 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 Gene3D G3DSA:1.10.10.10 2 84 7.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 61 1.1E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS12775 1cb1a1a4012e39f6ef84a19224d57fa9 303 SUPERFAMILY SSF53850 87 295 1.55E-35 T 06-07-2017 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Gene3D G3DSA:1.20.140.10 225 386 5.0E-42 T 06-07-2017 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 SUPERFAMILY SSF56645 6 236 6.02E-80 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 SUPERFAMILY SSF47203 242 388 2.09E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Gene3D G3DSA:2.40.110.10 134 224 5.0E-35 T 06-07-2017 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Gene3D G3DSA:1.10.540.10 5 133 1.4E-43 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 131 1.4E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 224 6.4E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK95_RS06370 99aa02ae6d04eb922a0077339443abcb 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 4.8E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS01255 c7fe15070c46f52e61a87910c19ac172 361 SUPERFAMILY SSF111369 50 274 3.53E-20 T 06-07-2017 CAK95_RS01255 c7fe15070c46f52e61a87910c19ac172 361 Gene3D G3DSA:2.40.50.100 62 142 2.1E-4 T 06-07-2017 CAK95_RS01255 c7fe15070c46f52e61a87910c19ac172 361 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 350 6.2E-60 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS01255 c7fe15070c46f52e61a87910c19ac172 361 Gene3D G3DSA:2.40.50.100 167 200 3.9E-12 T 06-07-2017 CAK95_RS01255 c7fe15070c46f52e61a87910c19ac172 361 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 270 4.7E-21 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS04870 b2e7591c19da58f9f56cc497480ecbbc 334 Pfam PF16344 Domain of unknown function (DUF4974) 234 317 1.1E-9 T 06-07-2017 IPR032508 Protein FecR, C-terminal CAK95_RS04870 b2e7591c19da58f9f56cc497480ecbbc 334 Pfam PF16220 Domain of unknown function (DUF4880) 36 67 8.3E-9 T 06-07-2017 IPR032623 FecR, N-terminal CAK95_RS04870 b2e7591c19da58f9f56cc497480ecbbc 334 Pfam PF04773 FecR protein 133 222 9.5E-9 T 06-07-2017 IPR006860 FecR protein CAK95_RS04870 b2e7591c19da58f9f56cc497480ecbbc 334 PIRSF PIRSF018266 26 332 2.1E-55 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAK95_RS19120 5053bb0b022a631f4f90eb8b1ab79738 336 Pfam PF05838 Glycosyl hydrolase 108 12 94 5.3E-29 T 06-07-2017 IPR008565 Protein of unknown function DUF847 CAK95_RS19120 5053bb0b022a631f4f90eb8b1ab79738 336 Gene3D G3DSA:1.20.141.10 4 169 1.3E-49 T 06-07-2017 CAK95_RS19120 5053bb0b022a631f4f90eb8b1ab79738 336 SUPERFAMILY SSF53955 5 164 6.19E-44 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS25785 bf6db316d0891b7c8c7e980149730950 186 Pfam PF05163 DinB family 3 168 5.7E-33 T 06-07-2017 IPR007837 DNA damage-inducible protein DinB CAK95_RS25785 bf6db316d0891b7c8c7e980149730950 186 SUPERFAMILY SSF109854 6 145 9.52E-38 T 06-07-2017 CAK95_RS25785 bf6db316d0891b7c8c7e980149730950 186 Gene3D G3DSA:1.20.120.450 1 163 1.5E-39 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 Pfam PF00884 Sulfatase 22 387 5.3E-53 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 Gene3D G3DSA:3.30.1120.10 425 458 6.0E-5 T 06-07-2017 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 Pfam PF14707 C-terminal region of aryl-sulfatase 427 485 3.9E-7 T 06-07-2017 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 Gene3D G3DSA:3.40.720.10 19 170 4.0E-83 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 Gene3D G3DSA:3.40.720.10 211 424 4.0E-83 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 SUPERFAMILY SSF53649 20 165 2.04E-98 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS10580 cc7bad23f5b6bfa129fb191c0a6e4110 559 SUPERFAMILY SSF53649 208 485 2.04E-98 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS16140 8a4d25fbf1719705cfad59edb0d8275f 268 SUPERFAMILY SSF53474 15 266 1.5E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16140 8a4d25fbf1719705cfad59edb0d8275f 268 Pfam PF12697 Alpha/beta hydrolase family 44 257 5.6E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16140 8a4d25fbf1719705cfad59edb0d8275f 268 Gene3D G3DSA:3.40.50.1820 9 264 6.1E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS14255 043a4a335995db81bb4da424dd4ceea2 341 PIRSF PIRSF017082 6 340 3.8E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14255 043a4a335995db81bb4da424dd4ceea2 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 337 1.6E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14255 043a4a335995db81bb4da424dd4ceea2 341 SUPERFAMILY SSF53850 132 304 2.2E-6 T 06-07-2017 CAK95_RS17160 72564b7d423f5054b51babdc1d775660 276 Gene3D G3DSA:3.20.20.150 6 266 4.8E-53 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS17160 72564b7d423f5054b51babdc1d775660 276 SUPERFAMILY SSF51658 10 273 1.93E-48 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS17160 72564b7d423f5054b51babdc1d775660 276 Pfam PF01261 Xylose isomerase-like TIM barrel 20 225 1.5E-28 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS02310 15730d572c1536267c7e1bf8837ffaf8 77 Pfam PF10038 Protein of unknown function (DUF2274) 1 70 6.0E-32 T 06-07-2017 IPR018733 Protein of unknown function DUF2274 CAK95_RS10860 7630ac0e5d9ab8b754b06445d3c9a851 320 SUPERFAMILY SSF53807 44 300 6.28E-52 T 06-07-2017 CAK95_RS10860 7630ac0e5d9ab8b754b06445d3c9a851 320 Gene3D G3DSA:3.40.50.1980 174 300 1.5E-21 T 06-07-2017 CAK95_RS10860 7630ac0e5d9ab8b754b06445d3c9a851 320 Gene3D G3DSA:3.40.50.1980 44 159 6.9E-21 T 06-07-2017 CAK95_RS10860 7630ac0e5d9ab8b754b06445d3c9a851 320 Pfam PF01497 Periplasmic binding protein 47 275 1.8E-30 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK95_RS19045 1fddb8a62d6dd89079a8d8b0a6b513f8 135 Pfam PF11367 Protein of unknown function (DUF3168) 11 128 1.4E-33 T 06-07-2017 IPR021508 Protein of unknown function DUF3168 CAK95_RS18430 061c93de985bccb5a14e840e45b4c2d6 328 SUPERFAMILY SSF53850 119 292 1.63E-10 T 06-07-2017 CAK95_RS18430 061c93de985bccb5a14e840e45b4c2d6 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.6E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18430 061c93de985bccb5a14e840e45b4c2d6 328 PIRSF PIRSF017082 1 326 1.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13940 04edc9cd418dbb85321ce4a0a826a0a2 268 Pfam PF01841 Transglutaminase-like superfamily 126 225 4.7E-21 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS13940 04edc9cd418dbb85321ce4a0a826a0a2 268 SUPERFAMILY SSF54001 49 254 7.57E-40 T 06-07-2017 CAK95_RS13940 04edc9cd418dbb85321ce4a0a826a0a2 268 SMART SM00460 161 227 8.5E-18 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS13940 04edc9cd418dbb85321ce4a0a826a0a2 268 Gene3D G3DSA:3.90.260.10 164 227 4.5E-12 T 06-07-2017 IPR002931 Transglutaminase-like CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 Pfam PF03466 LysR substrate binding domain 89 288 7.3E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 SUPERFAMILY SSF53850 89 288 6.33E-43 T 06-07-2017 CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 SUPERFAMILY SSF46785 4 85 2.99E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 Gene3D G3DSA:3.40.190.10 177 258 1.6E-21 T 06-07-2017 CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 Gene3D G3DSA:1.10.10.10 3 80 1.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 Gene3D G3DSA:3.40.190.10 92 176 4.9E-22 T 06-07-2017 CAK95_RS03375 71f79d3d250dde4b7ddc8bce4e7b07c7 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 9.6E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09900 13707f2c67ecd974a292f9c055fa426b 232 Gene3D G3DSA:3.40.50.300 1 227 1.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09900 13707f2c67ecd974a292f9c055fa426b 232 SUPERFAMILY SSF52540 2 227 2.83E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09900 13707f2c67ecd974a292f9c055fa426b 232 Pfam PF00005 ABC transporter 19 160 1.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS09900 13707f2c67ecd974a292f9c055fa426b 232 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09900 13707f2c67ecd974a292f9c055fa426b 232 SMART SM00382 26 209 9.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 SUPERFAMILY SSF52833 1 87 4.9E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 Gene3D G3DSA:1.20.1050.10 149 236 5.7E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 Gene3D G3DSA:1.20.1050.10 94 117 5.7E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 82 5.7E-21 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 Pfam PF00043 Glutathione S-transferase, C-terminal domain 150 230 7.8E-12 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 SUPERFAMILY SSF47616 157 237 4.78E-26 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 SUPERFAMILY SSF47616 75 125 4.78E-26 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS01140 19126f19c39d1739ee3db255107c02d5 257 Gene3D G3DSA:3.40.30.10 2 93 4.1E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 Pfam PF06742 Protein of unknown function (DUF1214) 343 454 6.0E-37 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 Gene3D G3DSA:2.60.120.600 300 476 1.6E-57 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 SUPERFAMILY SSF160935 37 476 2.48E-123 T 06-07-2017 CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 Gene3D G3DSA:1.10.3360.10 208 284 7.4E-6 T 06-07-2017 IPR023289 VPA0735-like domain CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 Pfam PF06863 Protein of unknown function (DUF1254) 74 206 9.7E-39 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS05085 24e73b699e2c6d295b8521765df27a7c 476 Gene3D G3DSA:2.60.40.1610 88 207 5.1E-19 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK95_RS26955 d6a955b7d4e440e65219469475905d36 335 Pfam PF05686 Glycosyl transferase family 90 214 326 1.5E-8 T 06-07-2017 IPR006598 Lipopolysaccharide-modifying protein CAK95_RS26955 d6a955b7d4e440e65219469475905d36 335 SMART SM00672 123 327 1.2E-4 T 06-07-2017 IPR006598 Lipopolysaccharide-modifying protein CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 SUPERFAMILY SSF51905 30 317 1.3E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 SUPERFAMILY SSF51905 500 559 1.3E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 Pfam PF05199 GMC oxidoreductase 415 551 1.3E-42 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 Pfam PF00732 GMC oxidoreductase 33 324 2.1E-91 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 283 297 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 110 133 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 Gene3D G3DSA:3.50.50.60 30 154 7.7E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 Gene3D G3DSA:3.50.50.60 494 557 7.7E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 Gene3D G3DSA:3.50.50.60 216 342 7.7E-124 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS11435 e1ad438290770c965f461c8bab6945ad 567 SUPERFAMILY SSF54373 319 501 3.83E-49 T 06-07-2017 CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 Gene3D G3DSA:3.40.50.720 10 276 3.6E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 Pfam PF00106 short chain dehydrogenase 10 189 1.4E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 SUPERFAMILY SSF51735 9 193 1.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 SUPERFAMILY SSF51735 222 274 1.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 181 0.0092 T 06-07-2017 CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS22145 51840eb3ab58400e0d6b9dbe8b4e349e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20310 df4ecd9befb5f72f7b918b825b1b38dd 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 289 1.2E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS18035 ac2511bb0ed94536bee813456377f68d 161 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 23 150 2.2E-47 T 06-07-2017 IPR003791 Protein of unknown function UPF0178 CAK95_RS18035 ac2511bb0ed94536bee813456377f68d 161 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 9 153 30.971 T 06-07-2017 IPR003791 Protein of unknown function UPF0178 CAK95_RS04255 6ff12d13d0249e53b831f7f1dcdd5a68 263 Pfam PF11412 Disulphide bond corrector protein DsbC 32 139 2.9E-21 T 06-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 SUPERFAMILY SSF56784 54 276 9.73E-34 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 Pfam PF13419 Haloacid dehalogenase-like hydrolase 131 247 1.5E-7 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 54 65 1.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 171 1.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 236 249 1.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK95_RS01220 fbb0b7a1b6b449242739eb09a16ae42b 290 Gene3D G3DSA:3.40.50.1000 54 276 5.5E-26 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS02285 b1c3384de82412a4cf6579db4048dbba 132 Gene3D G3DSA:3.30.420.10 4 124 4.7E-29 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS02285 b1c3384de82412a4cf6579db4048dbba 132 SUPERFAMILY SSF53098 4 124 2.02E-28 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS02285 b1c3384de82412a4cf6579db4048dbba 132 Pfam PF13683 Integrase core domain 58 123 1.4E-30 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 SUPERFAMILY SSF56645 16 229 6.68E-28 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 Gene3D G3DSA:1.20.140.10 223 365 2.5E-6 T 06-07-2017 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 SUPERFAMILY SSF47203 283 371 5.32E-7 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 121 4.1E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 Gene3D G3DSA:2.40.110.10 142 222 6.1E-14 T 06-07-2017 CAK95_RS21100 96ea21fc044cb9d1445b7089c038f10a 375 Gene3D G3DSA:1.10.540.10 15 120 1.4E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK95_RS19080 cb0b4c3141ed59a934ac6c3d76eaa2a6 298 Pfam PF09931 Uncharacterized conserved protein (DUF2163) 1 163 2.1E-56 T 06-07-2017 IPR019228 Bacteriophage phiJL001, Gp84, N-terminal CAK95_RS19080 cb0b4c3141ed59a934ac6c3d76eaa2a6 298 TIGRFAM TIGR02218 phg_TIGR02218: phage conserved hypothetical protein BR0599 23 293 1.5E-88 T 06-07-2017 IPR011928 Bacteriophage phiJL001, Gp84 CAK95_RS19080 cb0b4c3141ed59a934ac6c3d76eaa2a6 298 Pfam PF09356 Phage conserved hypothetical protein BR0599 195 277 9.3E-33 T 06-07-2017 IPR018964 Bacteriophage phiJL001, Gp84, C-terminal CAK95_RS16355 b7b4f0d6d7c7148d2675d57708e56310 173 Pfam PF03928 Haem-degrading 5 136 4.1E-22 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS16355 b7b4f0d6d7c7148d2675d57708e56310 173 SUPERFAMILY SSF143744 3 140 1.44E-25 T 06-07-2017 CAK95_RS18400 1659f60e8c0e4e2e32b99b3bccf9f398 154 Gene3D G3DSA:3.30.70.900 33 152 7.2E-18 T 06-07-2017 CAK95_RS18400 1659f60e8c0e4e2e32b99b3bccf9f398 154 SUPERFAMILY SSF54909 46 151 2.08E-8 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS18400 1659f60e8c0e4e2e32b99b3bccf9f398 154 Pfam PF07876 Stress responsive A/B Barrel Domain 48 151 6.8E-6 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel CAK95_RS24235 39334e29333bf19dd790a7cd3c472155 266 Pfam PF00535 Glycosyl transferase family 2 11 130 5.4E-25 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS24235 39334e29333bf19dd790a7cd3c472155 266 Gene3D G3DSA:3.90.550.10 8 179 1.8E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS24235 39334e29333bf19dd790a7cd3c472155 266 SUPERFAMILY SSF53448 9 232 8.63E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS16500 eca75d35e9c7b5f3531c8be240f2b1b2 294 SUPERFAMILY SSF53187 9 281 3.35E-83 T 06-07-2017 CAK95_RS16500 eca75d35e9c7b5f3531c8be240f2b1b2 294 Pfam PF05013 N-formylglutamate amidohydrolase 22 253 2.0E-69 T 06-07-2017 IPR007709 N-formylglutamate amidohydrolase CAK95_RS16500 eca75d35e9c7b5f3531c8be240f2b1b2 294 Gene3D G3DSA:3.40.630.40 5 280 1.0E-96 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK95_RS02975 26668a00efa154ba2b2ccf204e2443b0 148 Pfam PF11149 Protein of unknown function (DUF2924) 7 142 2.4E-52 T 06-07-2017 IPR021322 Protein of unknown function DUF2924 CAK95_RS21675 fc6115e5c3a7838424a7948393b0240a 198 Gene3D G3DSA:3.40.50.1820 2 195 7.5E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS21675 fc6115e5c3a7838424a7948393b0240a 198 SUPERFAMILY SSF53474 2 193 9.73E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS21675 fc6115e5c3a7838424a7948393b0240a 198 Pfam PF02230 Phospholipase/Carboxylesterase 90 190 7.3E-6 T 06-07-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 Pfam PF01702 Queuine tRNA-ribosyltransferase 131 362 2.3E-77 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 5 363 53.206 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 Gene3D G3DSA:3.20.20.105 2 363 3.9E-148 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 364 4.0E-134 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 365 2.7E-141 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS22275 24e33a596564c5dad9e73f1dcf58eb56 377 SUPERFAMILY SSF51713 5 362 5.75E-144 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK95_RS02795 5d305d8762cb9b251e4a94144cc62007 330 SUPERFAMILY SSF53850 117 291 3.85E-14 T 06-07-2017 CAK95_RS02795 5d305d8762cb9b251e4a94144cc62007 330 PIRSF PIRSF017082 1 330 6.5E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02795 5d305d8762cb9b251e4a94144cc62007 330 Gene3D G3DSA:3.40.190.10 129 229 1.8E-4 T 06-07-2017 CAK95_RS02795 5d305d8762cb9b251e4a94144cc62007 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 326 8.3E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 333 2.6E-147 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 117 2.6E-32 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 318 1.1E-57 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 SMART SM00859 4 119 3.9E-40 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 SUPERFAMILY SSF51735 3 157 6.42E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 Gene3D G3DSA:3.30.360.10 143 314 1.0E-82 T 06-07-2017 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 Gene3D G3DSA:3.40.50.720 1 142 2.6E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 PIRSF PIRSF000148 2 337 6.0E-131 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 332 36.685 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK95_RS07745 fb224241c4d68a9afa784e465465ad99 344 SUPERFAMILY SSF55347 129 319 2.98E-76 T 06-07-2017 CAK95_RS12565 1deeb7838a53a69a424725e74cca24a0 369 SUPERFAMILY SSF51726 10 368 1.11E-77 T 06-07-2017 CAK95_RS12565 1deeb7838a53a69a424725e74cca24a0 369 Gene3D G3DSA:3.20.20.210 4 368 7.4E-117 T 06-07-2017 CAK95_RS12565 1deeb7838a53a69a424725e74cca24a0 369 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 347 4.6E-15 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS18480 6bb96798eb593462d0396b89b5be39f7 155 Pfam PF07681 DoxX 33 119 7.7E-21 T 06-07-2017 IPR032808 DoxX family CAK95_RS25295 03af4ee76788bb923e76f07eb431d184 232 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 232 81.36 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAK95_RS25295 03af4ee76788bb923e76f07eb431d184 232 SUPERFAMILY SSF55729 14 208 1.62E-74 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS25295 03af4ee76788bb923e76f07eb431d184 232 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 17 188 9.7E-67 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAK95_RS25295 03af4ee76788bb923e76f07eb431d184 232 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 21 204 1.2E-55 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAK95_RS15985 1608e0232f32b020e6263f6cd92e5cd9 200 SUPERFAMILY SSF54427 5 137 1.42E-29 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS15985 1608e0232f32b020e6263f6cd92e5cd9 200 Gene3D G3DSA:3.10.450.50 4 132 1.6E-23 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS15985 1608e0232f32b020e6263f6cd92e5cd9 200 Pfam PF13577 SnoaL-like domain 6 122 2.6E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 Pfam PF12697 Alpha/beta hydrolase family 5 233 3.7E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 SUPERFAMILY SSF53474 4 237 5.27E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 29 44 2.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 2.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 2.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16480 1835f3b5279ccec8329abf5e5dce369c 241 Gene3D G3DSA:3.40.50.1820 4 237 8.2E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS27945 c23b9babee5d067169ec91054b0d1e14 269 Gene3D G3DSA:1.10.3720.10 74 268 3.7E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27945 c23b9babee5d067169ec91054b0d1e14 269 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 20 269 2.9E-88 T 06-07-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CAK95_RS27945 c23b9babee5d067169ec91054b0d1e14 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 263 8.2E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27945 c23b9babee5d067169ec91054b0d1e14 269 SUPERFAMILY SSF161098 74 260 7.59E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11310 58f5f8d851dc02770aed7f59114c9e53 161 PIRSF PIRSF032146 1 161 1.3E-80 T 06-07-2017 IPR008321 Uncharacterised conserved protein UCP032146 CAK95_RS11310 58f5f8d851dc02770aed7f59114c9e53 161 Pfam PF06793 Uncharacterised protein family (UPF0262) 9 160 3.4E-74 T 06-07-2017 IPR008321 Uncharacterised conserved protein UCP032146 CAK95_RS11310 58f5f8d851dc02770aed7f59114c9e53 161 Hamap MF_00678 UPF0262 protein . 8 160 40.524 T 06-07-2017 IPR008321 Uncharacterised conserved protein UCP032146 CAK95_RS07395 fffe72c7ea97996ae8936876ba738c81 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 5.6E-29 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAK95_RS07395 fffe72c7ea97996ae8936876ba738c81 104 SUPERFAMILY SSF103481 5 102 9.29E-19 T 06-07-2017 CAK95_RS17475 ce276d873980be6b2aed989c399e047d 234 SUPERFAMILY SSF52540 2 232 7.94E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17475 ce276d873980be6b2aed989c399e047d 234 SMART SM00382 26 213 2.5E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS17475 ce276d873980be6b2aed989c399e047d 234 Gene3D G3DSA:3.40.50.300 1 231 1.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17475 ce276d873980be6b2aed989c399e047d 234 Pfam PF00005 ABC transporter 17 162 1.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS17475 ce276d873980be6b2aed989c399e047d 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS09010 757801f475150db8c62633b0866dd993 143 Pfam PF07886 BA14K-like protein 114 143 2.8E-15 T 06-07-2017 IPR012413 BA14k family GO:0009405 CAK95_RS09330 455a21739f988bac645fb438c104ad3c 209 SUPERFAMILY SSF81452 19 206 3.14E-57 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09330 455a21739f988bac645fb438c104ad3c 209 Pfam PF00510 Cytochrome c oxidase subunit III 28 206 6.0E-13 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09330 455a21739f988bac645fb438c104ad3c 209 Gene3D G3DSA:1.20.120.80 29 206 3.2E-49 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS09330 455a21739f988bac645fb438c104ad3c 209 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 29 208 6.3E-80 T 06-07-2017 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CAK95_RS20050 f50e779f4446d2bf529024dfbc5cb0f7 173 Gene3D G3DSA:3.40.630.30 6 163 6.9E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS20050 f50e779f4446d2bf529024dfbc5cb0f7 173 SUPERFAMILY SSF55729 8 161 2.44E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS20050 f50e779f4446d2bf529024dfbc5cb0f7 173 Pfam PF13673 Acetyltransferase (GNAT) domain 34 150 1.7E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 Gene3D G3DSA:3.40.1280.10 9 247 1.3E-70 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 SUPERFAMILY SSF88697 8 78 5.47E-16 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 PIRSF PIRSF015601 8 247 5.8E-54 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 20 246 1.1E-36 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 Pfam PF04452 RNA methyltransferase 25 241 3.5E-58 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK95_RS13445 0637d2c5a7ec0356691d359a029fff78 248 SUPERFAMILY SSF75217 80 247 2.88E-45 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS04445 bbfb66f460f52e595eab6297590e5d45 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 288 2.3E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 SUPERFAMILY SSF53335 289 366 4.66E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 SUPERFAMILY SSF53335 128 212 4.66E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 SUPERFAMILY SSF53335 3 82 4.66E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 Gene3D G3DSA:3.40.50.150 131 196 4.7E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 Gene3D G3DSA:3.40.50.150 3 85 4.7E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 Gene3D G3DSA:3.40.50.150 286 368 4.7E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 26 31 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 304 321 6.1E-30 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 59 79 6.1E-30 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 323 341 6.1E-30 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 21 35 6.1E-30 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 346 366 6.1E-30 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAK95_RS24320 afd69fdcd5e8a72d74e3b1e812e9a0d8 376 Pfam PF01555 DNA methylase 22 361 7.6E-49 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS20840 ed7166dd4c130b8da9b703fb34f514e4 277 Pfam PF13560 Helix-turn-helix domain 7 84 2.2E-17 T 06-07-2017 CAK95_RS20840 ed7166dd4c130b8da9b703fb34f514e4 277 Gene3D G3DSA:1.10.260.40 21 77 1.5E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS20840 ed7166dd4c130b8da9b703fb34f514e4 277 SMART SM00530 10 81 1.2E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS20840 ed7166dd4c130b8da9b703fb34f514e4 277 SUPERFAMILY SSF47413 27 74 5.3E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS27370 f03676c152816547becfcb63aa251fd1 168 Pfam PF00866 Ring hydroxylating beta subunit 26 156 3.1E-32 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAK95_RS27370 f03676c152816547becfcb63aa251fd1 168 SUPERFAMILY SSF54427 16 164 1.92E-43 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS27370 f03676c152816547becfcb63aa251fd1 168 Gene3D G3DSA:3.10.450.50 16 167 7.7E-49 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS03650 f5ecd7bc606110a7c3a9645f3790cd1b 272 Gene3D G3DSA:1.10.10.10 29 121 7.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03650 f5ecd7bc606110a7c3a9645f3790cd1b 272 SUPERFAMILY SSF46785 39 93 1.28E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS03650 f5ecd7bc606110a7c3a9645f3790cd1b 272 Pfam PF13730 Helix-turn-helix domain 30 82 2.6E-12 T 06-07-2017 CAK95_RS17465 e6e0d29dd8d52ab5d950e8e033393dea 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 288 5.6E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS19985 0d8a0c9690f235622847d9650118c394 175 SUPERFAMILY SSF46785 19 162 4.81E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19985 0d8a0c9690f235622847d9650118c394 175 Gene3D G3DSA:1.10.10.10 13 162 1.0E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS19985 0d8a0c9690f235622847d9650118c394 175 Pfam PF01047 MarR family 59 113 1.5E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS19985 0d8a0c9690f235622847d9650118c394 175 SMART SM00347 49 149 4.9E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS09220 07c04f603fc6294f6f7d75534bf4365d 335 Gene3D G3DSA:3.40.50.300 119 322 9.8E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09220 07c04f603fc6294f6f7d75534bf4365d 335 SUPERFAMILY SSF54791 18 74 1.74E-5 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK95_RS09220 07c04f603fc6294f6f7d75534bf4365d 335 SUPERFAMILY SSF52540 114 286 7.04E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09220 07c04f603fc6294f6f7d75534bf4365d 335 Pfam PF02562 PhoH-like protein 120 323 7.3E-90 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 CAK95_RS03290 4b16456fcac3c6f42b75e1b69f238d5a 187 Gene3D G3DSA:3.10.129.10 74 185 4.7E-22 T 06-07-2017 IPR029069 HotDog domain CAK95_RS03290 4b16456fcac3c6f42b75e1b69f238d5a 187 Pfam PF01575 MaoC like domain 79 163 4.3E-18 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS03290 4b16456fcac3c6f42b75e1b69f238d5a 187 SUPERFAMILY SSF54637 61 163 9.56E-21 T 06-07-2017 IPR029069 HotDog domain CAK95_RS16055 e0f255672c0497fe3ce33e6d11344176 31 Pfam PF08042 PqqA family 8 26 2.1E-7 T 06-07-2017 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CAK95_RS16055 e0f255672c0497fe3ce33e6d11344176 31 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 9 26 4.0E-6 T 06-07-2017 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CAK95_RS18860 a824d2376941404679203a81696d69e0 117 Pfam PF01471 Putative peptidoglycan binding domain 54 104 3.0E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS18860 a824d2376941404679203a81696d69e0 117 Gene3D G3DSA:1.10.101.10 52 109 2.8E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS18860 a824d2376941404679203a81696d69e0 117 SUPERFAMILY SSF47090 52 109 4.08E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK95_RS28695 39cff29e9bb26ea9cc0890632667e9dc 351 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 5 342 1.0E-45 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAK95_RS28695 39cff29e9bb26ea9cc0890632667e9dc 351 Pfam PF13816 Haem-containing dehydratase 40 341 5.6E-75 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 Gene3D G3DSA:3.40.190.10 91 176 8.9E-19 T 06-07-2017 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 Gene3D G3DSA:1.10.10.10 2 85 2.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 SUPERFAMILY SSF53850 90 294 1.09E-37 T 06-07-2017 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 SUPERFAMILY SSF46785 2 111 1.87E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 Gene3D G3DSA:3.40.190.10 177 268 1.6E-26 T 06-07-2017 CAK95_RS09140 5be7a590d55a4b43673f8fcac5a5465a 295 Pfam PF03466 LysR substrate binding domain 89 293 2.0E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS27880 edc08e5964f2e6a1479353805541e86f 203 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 29 121 5.1E-18 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS27880 edc08e5964f2e6a1479353805541e86f 203 SUPERFAMILY SSF50475 28 149 2.69E-23 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS27880 edc08e5964f2e6a1479353805541e86f 203 Gene3D G3DSA:2.30.110.10 27 146 2.9E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS27880 edc08e5964f2e6a1479353805541e86f 203 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 8 203 2.1E-80 T 06-07-2017 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CAK95_RS20860 eac9c29cc5e3e1e3c73e797c397e83e7 161 Pfam PF01575 MaoC like domain 20 127 1.9E-22 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS20860 eac9c29cc5e3e1e3c73e797c397e83e7 161 Gene3D G3DSA:3.10.129.10 9 159 1.5E-43 T 06-07-2017 IPR029069 HotDog domain CAK95_RS20860 eac9c29cc5e3e1e3c73e797c397e83e7 161 SUPERFAMILY SSF54637 12 159 1.27E-42 T 06-07-2017 IPR029069 HotDog domain CAK95_RS02120 88c23816370c24a23a6b5b3321b94da0 227 SUPERFAMILY SSF52499 20 220 1.96E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS02120 88c23816370c24a23a6b5b3321b94da0 227 Gene3D G3DSA:3.40.50.850 18 221 7.6E-48 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS02120 88c23816370c24a23a6b5b3321b94da0 227 Pfam PF00857 Isochorismatase family 36 212 2.3E-32 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS23435 92e9f021d1460c3b95d065ce659848e8 189 SUPERFAMILY SSF52833 33 176 9.18E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23435 92e9f021d1460c3b95d065ce659848e8 189 Pfam PF13098 Thioredoxin-like domain 54 165 1.3E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23435 92e9f021d1460c3b95d065ce659848e8 189 Gene3D G3DSA:3.40.30.10 44 178 1.2E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS17150 39df7ebbee3956cca0ceb11bf80e5a7b 412 SUPERFAMILY SSF75011 31 69 3.66E-6 T 06-07-2017 CAK95_RS17150 39df7ebbee3956cca0ceb11bf80e5a7b 412 SUPERFAMILY SSF75011 108 155 3.66E-6 T 06-07-2017 CAK95_RS17150 39df7ebbee3956cca0ceb11bf80e5a7b 412 SUPERFAMILY SSF75011 231 387 3.66E-6 T 06-07-2017 CAK95_RS17150 39df7ebbee3956cca0ceb11bf80e5a7b 412 Pfam PF08309 LVIVD repeat 226 245 1.0 T 06-07-2017 IPR013211 LVIVD CAK95_RS28380 9d036120bd3973812919471d828ed8ed 127 Gene3D G3DSA:3.30.429.10 2 119 2.0E-36 T 06-07-2017 CAK95_RS28380 9d036120bd3973812919471d828ed8ed 127 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 120 1.2E-10 T 06-07-2017 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 CAK95_RS28380 9d036120bd3973812919471d828ed8ed 127 SUPERFAMILY SSF55331 2 117 4.07E-32 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK95_RS01335 7fa2ffa1b648bb81f7b10098fa228997 159 Gene3D G3DSA:2.60.120.10 68 146 2.4E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS01335 7fa2ffa1b648bb81f7b10098fa228997 159 Pfam PF07883 Cupin domain 79 146 4.1E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS01335 7fa2ffa1b648bb81f7b10098fa228997 159 SUPERFAMILY SSF51182 70 154 1.78E-14 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS07965 448728ee841a8513b5464c89b1a9b648 297 SUPERFAMILY SSF103088 171 278 7.46E-25 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS07965 448728ee841a8513b5464c89b1a9b648 297 Pfam PF00691 OmpA family 175 272 2.7E-18 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS07965 448728ee841a8513b5464c89b1a9b648 297 Gene3D G3DSA:3.30.1330.60 171 278 4.1E-28 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS07005 f5f34ccfe16cc0b5959d212f75e196b7 258 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS07005 f5f34ccfe16cc0b5959d212f75e196b7 258 SMART SM00382 30 217 1.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS07005 f5f34ccfe16cc0b5959d212f75e196b7 258 SUPERFAMILY SSF52540 4 228 2.71E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07005 f5f34ccfe16cc0b5959d212f75e196b7 258 Gene3D G3DSA:3.40.50.300 7 236 2.9E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07005 f5f34ccfe16cc0b5959d212f75e196b7 258 Pfam PF00005 ABC transporter 22 168 6.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27705 0136af285936d3b72e3b7e1ab2fa2f10 220 SUPERFAMILY SSF54909 112 184 8.85E-8 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS27705 0136af285936d3b72e3b7e1ab2fa2f10 220 SUPERFAMILY SSF54909 12 58 7.6E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 Pfam PF01494 FAD binding domain 8 339 8.8E-59 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 2.6E-27 T 06-07-2017 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.6E-27 T 06-07-2017 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 2.6E-27 T 06-07-2017 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 2.6E-27 T 06-07-2017 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 331 2.6E-27 T 06-07-2017 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 SUPERFAMILY SSF51905 267 344 2.12E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 SUPERFAMILY SSF51905 8 179 2.12E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 Gene3D G3DSA:3.50.50.60 8 184 3.4E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS18550 9fe86ec6f4fabc8e73de2d2bf7afee7f 399 Gene3D G3DSA:3.50.50.60 268 343 3.4E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15965 3d9f40ed4fc40f4719e3358ac6f44436 469 SUPERFAMILY SSF53335 298 344 3.43E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15965 3d9f40ed4fc40f4719e3358ac6f44436 469 SUPERFAMILY SSF53335 127 188 3.43E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS11535 bbf62e6af413ec8c8e5578f280ea639b 329 Gene3D G3DSA:3.90.850.10 75 326 5.9E-63 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS11535 bbf62e6af413ec8c8e5578f280ea639b 329 SUPERFAMILY SSF56529 124 325 2.35E-59 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS11535 bbf62e6af413ec8c8e5578f280ea639b 329 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 123 325 4.5E-55 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS17840 85d0e2c1d77ab1aa70d63d217eecd12d 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.6E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17840 85d0e2c1d77ab1aa70d63d217eecd12d 326 PIRSF PIRSF017082 1 324 9.1E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS17840 85d0e2c1d77ab1aa70d63d217eecd12d 326 SUPERFAMILY SSF53850 112 286 1.88E-12 T 06-07-2017 CAK95_RS00570 19674b0042c41bd2e29cbaeb364edd86 159 Pfam PF00588 SpoU rRNA Methylase family 7 145 2.1E-31 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK95_RS00570 19674b0042c41bd2e29cbaeb364edd86 159 SUPERFAMILY SSF75217 4 153 1.77E-39 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK95_RS00570 19674b0042c41bd2e29cbaeb364edd86 159 Gene3D G3DSA:3.40.1280.10 6 155 5.6E-49 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK95_RS00570 19674b0042c41bd2e29cbaeb364edd86 159 PIRSF PIRSF029256 6 158 4.6E-52 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAK95_RS00570 19674b0042c41bd2e29cbaeb364edd86 159 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 7 156 29.468 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAK95_RS03270 511e82efe3cb7482bec6cde58ed0f6b4 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 5.0E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05215 d900f3ca4f4abfa97ff81cbe1cd4ac93 438 Pfam PF03929 PepSY-associated TM region 7 406 5.2E-48 T 06-07-2017 IPR005625 PepSY-associated TM protein CAK95_RS13800 d657bc67bbaa9e5decfb57331b111849 385 Pfam PF03631 Virulence factor BrkB 102 356 2.6E-60 T 06-07-2017 IPR017039 Virulence factor BrkB CAK95_RS13800 d657bc67bbaa9e5decfb57331b111849 385 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 95 353 9.4E-33 T 06-07-2017 IPR017039 Virulence factor BrkB CAK95_RS12000 799f66162601cae204194c8f9ac3006e 189 SUPERFAMILY SSF55961 21 175 7.81E-19 T 06-07-2017 CAK95_RS12000 799f66162601cae204194c8f9ac3006e 189 Gene3D G3DSA:3.30.530.20 23 175 1.3E-8 T 06-07-2017 IPR023393 START-like domain CAK95_RS12000 799f66162601cae204194c8f9ac3006e 189 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 29 174 1.1E-15 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK95_RS16685 eacd9729c6b8bd30ca5d7e7e905392a4 466 Pfam PF07995 Glucose / Sorbosone dehydrogenase 201 368 5.2E-13 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAK95_RS16685 eacd9729c6b8bd30ca5d7e7e905392a4 466 Gene3D G3DSA:2.120.10.30 72 444 3.7E-60 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS16685 eacd9729c6b8bd30ca5d7e7e905392a4 466 SUPERFAMILY SSF50952 134 443 1.06E-36 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK95_RS16685 eacd9729c6b8bd30ca5d7e7e905392a4 466 SUPERFAMILY SSF50952 75 106 1.06E-36 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 SUPERFAMILY SSF46894 196 256 2.28E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 231 243 3.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 215 3.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 231 3.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 SMART SM00421 198 255 2.2E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 Gene3D G3DSA:1.10.10.10 200 253 1.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28690 a43d0b1fecbaad2248920287630806d3 270 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 251 1.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 189 286 2.8E-22 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 Gene3D G3DSA:2.60.120.330 11 326 5.0E-109 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 PRINTS PR00682 Isopenicillin N synthase signature 38 55 1.4E-14 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 PRINTS PR00682 Isopenicillin N synthase signature 247 273 1.4E-14 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 PRINTS PR00682 Isopenicillin N synthase signature 161 177 1.4E-14 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 SUPERFAMILY SSF51197 12 325 2.33E-101 T 06-07-2017 CAK95_RS28580 77862702bb19e104ec1ee1fac11cd775 326 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 15 139 3.5E-36 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 26 411 3.0E-169 T 06-07-2017 CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 Gene3D G3DSA:3.60.70.12 16 285 5.4E-92 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 SUPERFAMILY SSF56266 19 410 1.01E-132 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 Pfam PF01960 ArgJ family 24 413 1.4E-137 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 413 149.083 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS10460 ea40ae8b86d74c6fcf0cfe1e988e167f 413 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 413 7.0E-112 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 SUPERFAMILY SSF52540 363 612 2.55E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 592 679 6.2E-25 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 333 3.2E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 SMART SM00382 398 591 2.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 SMART SM00382 48 248 2.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 SUPERFAMILY SSF52540 19 268 3.19E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Pfam PF00005 ABC transporter 40 198 5.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Pfam PF00005 ABC transporter 390 541 5.4E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 593 660 1.4E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 315 1.2E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Gene3D G3DSA:3.40.50.300 18 272 9.4E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 Gene3D G3DSA:3.40.50.300 362 615 1.3E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS13680 21961006edda62270288c88cb9bb1716 681 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS27095 24ba51a895275ac0770a34c6b265e668 138 Gene3D G3DSA:2.60.40.790 9 132 4.5E-14 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS27095 24ba51a895275ac0770a34c6b265e668 138 SUPERFAMILY SSF49764 23 135 9.16E-17 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS04275 3c468e6891ff1ad5ef40c787ecf981cc 328 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 15 297 5.1E-93 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS04275 3c468e6891ff1ad5ef40c787ecf981cc 328 Pfam PF02401 LytB protein 16 294 6.8E-84 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS04275 3c468e6891ff1ad5ef40c787ecf981cc 328 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 14 299 35.924 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 SUPERFAMILY SSF48008 71 205 8.63E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 SUPERFAMILY SSF46785 5 85 1.53E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 Gene3D G3DSA:1.10.10.10 5 66 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 Gene3D G3DSA:1.20.120.530 67 207 8.1E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 Pfam PF07729 FCD domain 74 196 1.1E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 SMART SM00895 74 197 7.7E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 SMART SM00345 6 64 7.4E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS17515 9f29efb5acbdb1d713893169537b73ff 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 64 3.4E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK95_RS24505 ae5737db89c127373b475c904c00a277 165 Pfam PF04480 Protein of unknown function (DUF559) 76 153 2.5E-5 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK95_RS24505 ae5737db89c127373b475c904c00a277 165 SUPERFAMILY SSF52980 75 158 6.43E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK95_RS06360 9239e7b95c8258796506c168d1d0555f 280 Pfam PF07859 alpha/beta hydrolase fold 69 183 1.1E-10 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK95_RS06360 9239e7b95c8258796506c168d1d0555f 280 Gene3D G3DSA:3.40.50.1820 38 264 1.6E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06360 9239e7b95c8258796506c168d1d0555f 280 SUPERFAMILY SSF53474 6 259 3.44E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 230 6.9E-46 T 06-07-2017 CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 SUPERFAMILY SSF51735 3 230 1.05E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 Gene3D G3DSA:3.40.50.720 2 230 4.9E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS20355 478daa0a1b01e3231e55ee6e500f6a67 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21395 7c30f9c4475205f95fd23d34687d3183 97 SUPERFAMILY SSF54909 1 95 6.04E-29 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS21395 7c30f9c4475205f95fd23d34687d3183 97 Pfam PF07045 Domain of unknown function (DUF1330) 3 95 2.7E-32 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 CAK95_RS21395 7c30f9c4475205f95fd23d34687d3183 97 Gene3D G3DSA:3.30.70.900 1 96 5.2E-32 T 06-07-2017 CAK95_RS16675 119b8f4ccb698c64e892689de25fc8e8 274 SUPERFAMILY SSF53335 85 251 5.31E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS16675 119b8f4ccb698c64e892689de25fc8e8 274 Gene3D G3DSA:3.40.50.150 93 259 7.2E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS16675 119b8f4ccb698c64e892689de25fc8e8 274 Pfam PF05050 Methyltransferase FkbM domain 96 249 3.5E-14 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS10610 5a02a1198337c596b209d0197d4a94eb 386 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 112 383 1.6E-57 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS10610 5a02a1198337c596b209d0197d4a94eb 386 SUPERFAMILY SSF53850 216 354 2.39E-5 T 06-07-2017 CAK95_RS07550 7f41288817fff9a86ac33d593d1e1b66 124 Pfam PF10984 Protein of unknown function (DUF2794) 28 112 4.1E-41 T 06-07-2017 IPR021252 Protein of unknown function DUF2794 CAK95_RS15105 0edf7d2d83a74f59797058c227997714 266 SUPERFAMILY SSF53474 36 264 3.16E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15105 0edf7d2d83a74f59797058c227997714 266 Gene3D G3DSA:3.40.50.1820 35 264 1.2E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15105 0edf7d2d83a74f59797058c227997714 266 Pfam PF12697 Alpha/beta hydrolase family 37 170 1.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 SMART SM00411 29 117 2.8E-27 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 PRINTS PR01727 Prokaryotic integration host factor signature 68 83 5.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 PRINTS PR01727 Prokaryotic integration host factor signature 102 116 5.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 PRINTS PR01727 Prokaryotic integration host factor signature 86 99 5.8E-12 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 Pfam PF00216 Bacterial DNA-binding protein 30 117 5.5E-28 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 Gene3D G3DSA:4.10.520.10 29 117 7.9E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS26330 33308b892982c01739d7f6300c72a8d5 117 SUPERFAMILY SSF47729 30 117 8.83E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS05130 25446b15f87817d10c2164fe96870aa7 394 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 135 348 1.2E-68 T 06-07-2017 IPR010297 Protein of unknown function DUF900, hydrolase-like CAK95_RS05130 25446b15f87817d10c2164fe96870aa7 394 Gene3D G3DSA:3.40.50.1820 152 313 6.8E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS05130 25446b15f87817d10c2164fe96870aa7 394 PIRSF PIRSF033909 19 394 2.5E-115 T 06-07-2017 IPR014586 Uncharacterised conserved protein UCP033909 CAK95_RS05130 25446b15f87817d10c2164fe96870aa7 394 SUPERFAMILY SSF53474 146 320 3.72E-10 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01500 f6b0ab9579a44f1cd03cbe53e7c5173a 151 Gene3D G3DSA:3.90.420.10 61 126 1.1E-12 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS01500 f6b0ab9579a44f1cd03cbe53e7c5173a 151 Pfam PF00174 Oxidoreductase molybdopterin binding domain 61 126 1.9E-10 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS01500 f6b0ab9579a44f1cd03cbe53e7c5173a 151 SUPERFAMILY SSF56524 30 127 7.72E-15 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS23695 0dcf57d0625a4d726a9d951e555116a5 240 Pfam PF13505 Outer membrane protein beta-barrel domain 15 239 2.0E-20 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS23695 0dcf57d0625a4d726a9d951e555116a5 240 Gene3D G3DSA:2.40.160.20 35 239 5.9E-40 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS23695 0dcf57d0625a4d726a9d951e555116a5 240 SUPERFAMILY SSF56925 41 239 4.08E-31 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS22785 a6def90bd26d704f575a917ef329a4fd 445 Pfam PF09967 VWA-like domain (DUF2201) 318 441 3.3E-14 T 06-07-2017 IPR018698 VWA-like domain CAK95_RS22785 a6def90bd26d704f575a917ef329a4fd 445 Pfam PF13203 Putative metallopeptidase domain 50 309 1.4E-14 T 06-07-2017 IPR025154 Putative metallopeptidase domain CAK95_RS22785 a6def90bd26d704f575a917ef329a4fd 445 Gene3D G3DSA:3.30.2010.10 71 108 1.4E-4 T 06-07-2017 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 Gene3D G3DSA:1.10.10.10 31 164 2.5E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 SMART SM00347 52 152 9.6E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 Pfam PF01047 MarR family 59 115 4.6E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 2.8E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 2.8E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 2.8E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS06210 c0b287ad005f36f9b02eede0dd349c6d 167 SUPERFAMILY SSF46785 28 164 2.08E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 SUPERFAMILY SSF52540 2 51 1.09E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 SUPERFAMILY SSF52540 241 356 1.09E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 284 352 1.1E-15 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 PIRSF PIRSF029347 2 388 1.9E-116 T 06-07-2017 IPR014555 RecF-like CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 Gene3D G3DSA:3.40.50.300 188 363 3.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 Gene3D G3DSA:3.40.50.300 2 83 3.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00580 6ca89dfa206128d7818093b0e02c2c12 390 Gene3D G3DSA:3.40.50.300 140 141 3.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS24055 0b81abca40280705d153f1a8fd4aa34a 324 SUPERFAMILY SSF53850 80 281 1.15E-12 T 06-07-2017 CAK95_RS24055 0b81abca40280705d153f1a8fd4aa34a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.7E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS24055 0b81abca40280705d153f1a8fd4aa34a 324 PIRSF PIRSF017082 1 323 5.9E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS24230 a06b33d94d759e48bc1c9d5d0bce125d 111 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 24 104 4.0E-24 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS24230 a06b33d94d759e48bc1c9d5d0bce125d 111 PIRSF PIRSF028440 2 110 2.0E-46 T 06-07-2017 IPR014546 Uncharacterised conserved protein, lipid A biosynthesis CAK95_RS24230 a06b33d94d759e48bc1c9d5d0bce125d 111 SMART SM01259 27 98 5.2E-47 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS24230 a06b33d94d759e48bc1c9d5d0bce125d 111 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 27 97 2.7E-32 T 06-07-2017 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 Gene3D G3DSA:3.40.50.720 23 118 3.0E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 SUPERFAMILY SSF52283 27 138 4.73E-26 T 06-07-2017 CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 SUPERFAMILY SSF51735 104 286 3.25E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 40 316 2.2E-23 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 Gene3D G3DSA:3.40.50.720 119 287 3.1E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK95_RS08275 6fd6804d5d73f907dfa931f4d916aadc 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 285 4.7E-48 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK95_RS14950 18062c9cf5fb1f0b1a02675e02be27e3 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 328 1.8E-17 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS24840 47763621399012c0a1b77cf807dffba9 261 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 81 225 3.8E-28 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS24840 47763621399012c0a1b77cf807dffba9 261 Gene3D G3DSA:3.40.50.150 62 246 3.4E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS24840 47763621399012c0a1b77cf807dffba9 261 Pfam PF05050 Methyltransferase FkbM domain 83 244 3.6E-15 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS24840 47763621399012c0a1b77cf807dffba9 261 SUPERFAMILY SSF53335 33 250 7.19E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS12040 d2f58469c625e15a3314b786b42e3200 214 Gene3D G3DSA:1.20.1050.10 93 196 1.2E-14 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS12040 d2f58469c625e15a3314b786b42e3200 214 Gene3D G3DSA:3.40.30.10 18 92 4.7E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12040 d2f58469c625e15a3314b786b42e3200 214 Pfam PF02798 Glutathione S-transferase, N-terminal domain 18 79 1.6E-15 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS12040 d2f58469c625e15a3314b786b42e3200 214 SUPERFAMILY SSF47616 85 204 8.21E-21 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS12040 d2f58469c625e15a3314b786b42e3200 214 SUPERFAMILY SSF52833 18 81 7.63E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS15630 9cf1e2632e80960b05a0c8ceb3ed628e 305 SUPERFAMILY SSF51556 123 302 8.75E-17 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS15630 9cf1e2632e80960b05a0c8ceb3ed628e 305 SUPERFAMILY SSF51556 19 85 8.75E-17 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS15630 9cf1e2632e80960b05a0c8ceb3ed628e 305 Gene3D G3DSA:3.20.20.140 189 302 4.1E-4 T 06-07-2017 CAK95_RS12555 d97d0fad1b0bde9a69f7c3b3f7790483 197 Pfam PF00866 Ring hydroxylating beta subunit 53 185 1.1E-29 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAK95_RS12555 d97d0fad1b0bde9a69f7c3b3f7790483 197 Gene3D G3DSA:3.10.450.50 48 196 9.0E-46 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS12555 d97d0fad1b0bde9a69f7c3b3f7790483 197 SUPERFAMILY SSF54427 51 196 2.4E-40 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS13070 b0a067446a282b36f9aa715c086f97be 307 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 39 267 1.3E-10 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAK95_RS13070 b0a067446a282b36f9aa715c086f97be 307 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 41 268 1.4E-14 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAK95_RS10245 5117ec3b09229104cc60479137275961 125 Gene3D G3DSA:1.20.1290.10 4 121 6.1E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS10245 5117ec3b09229104cc60479137275961 125 SUPERFAMILY SSF69118 3 120 6.54E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS10245 5117ec3b09229104cc60479137275961 125 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 9.6E-22 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 155 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 470 485 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 118 136 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 416 434 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 494 511 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 47 72 1.7E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 Pfam PF01019 Gamma-glutamyltranspeptidase 40 597 9.4E-126 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 SUPERFAMILY SSF56235 13 375 5.71E-145 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS12490 1a32861aa91248465cec07a54d1005ae 605 SUPERFAMILY SSF56235 411 604 5.71E-145 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 Gene3D G3DSA:2.30.40.10 471 527 1.1E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 Pfam PF07969 Amidohydrolase family 49 528 3.8E-79 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 Gene3D G3DSA:2.30.40.10 4 97 3.6E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 Gene3D G3DSA:3.20.20.140 282 470 1.0E-21 T 06-07-2017 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 SUPERFAMILY SSF51338 487 530 3.72E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 SUPERFAMILY SSF51338 6 61 3.72E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 SUPERFAMILY SSF51556 195 488 1.72E-27 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00925 4f96cf622bb175b40a0b4b99ae995cac 544 SUPERFAMILY SSF51556 60 81 1.72E-27 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS28515 435ac065195bee49741936fafe865e18 401 Pfam PF13433 Periplasmic binding protein domain 39 398 1.7E-131 T 06-07-2017 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 SUPERFAMILY SSF53822 37 397 1.04E-90 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS28515 435ac065195bee49741936fafe865e18 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.6E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 291 304 1.6E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 101 111 1.6E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 Gene3D G3DSA:3.40.50.2300 32 156 4.6E-52 T 06-07-2017 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 Gene3D G3DSA:3.40.50.2300 310 367 4.6E-52 T 06-07-2017 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 Gene3D G3DSA:3.40.50.2300 157 309 5.2E-19 T 06-07-2017 CAK95_RS28515 435ac065195bee49741936fafe865e18 401 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 38 396 6.5E-165 T 06-07-2017 IPR017777 ABC transporter, urea, substrate-binding, UrtA CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 175 1.1E-48 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 SUPERFAMILY SSF52467 161 355 1.51E-39 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 538 9.0E-41 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 SUPERFAMILY SSF52518 8 179 1.95E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 SUPERFAMILY SSF52518 368 548 2.14E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 330 2.7E-32 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Gene3D G3DSA:3.40.50.970 387 549 2.3E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Gene3D G3DSA:3.40.50.970 8 183 2.1E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 Gene3D G3DSA:3.40.50.1220 190 386 2.5E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK95_RS00790 ede7c4ddc85ba2c25227a475e9de75d6 563 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK95_RS00170 f9cbfd69f0231c03d61d608590804584 315 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 275 3.0E-24 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS00170 f9cbfd69f0231c03d61d608590804584 315 Gene3D G3DSA:3.10.180.10 1 127 3.4E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00170 f9cbfd69f0231c03d61d608590804584 315 Gene3D G3DSA:3.10.180.10 135 314 3.4E-47 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS00170 f9cbfd69f0231c03d61d608590804584 315 SUPERFAMILY SSF54593 1 303 5.23E-48 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS15640 178e00fe55844374b0be439c1e8af5b7 291 Pfam PF04909 Amidohydrolase 5 279 4.9E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS15640 178e00fe55844374b0be439c1e8af5b7 291 SUPERFAMILY SSF51556 4 278 2.61E-53 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS15640 178e00fe55844374b0be439c1e8af5b7 291 Gene3D G3DSA:3.20.20.140 4 279 1.2E-67 T 06-07-2017 CAK95_RS23220 8463f99939094b812adae6afd02d9cc2 71 Pfam PF07311 Dodecin 5 68 4.4E-32 T 06-07-2017 IPR009923 Dodecin CAK95_RS23220 8463f99939094b812adae6afd02d9cc2 71 Gene3D G3DSA:3.30.1660.10 3 69 1.3E-36 T 06-07-2017 IPR025543 Dodecin-like CAK95_RS23220 8463f99939094b812adae6afd02d9cc2 71 SUPERFAMILY SSF89807 5 69 9.94E-28 T 06-07-2017 IPR009923 Dodecin CAK95_RS13885 c358f90abd765f2d7eebe6ba0afc14b9 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 3.2E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13885 c358f90abd765f2d7eebe6ba0afc14b9 326 SUPERFAMILY SSF53850 91 280 1.01E-9 T 06-07-2017 CAK95_RS13885 c358f90abd765f2d7eebe6ba0afc14b9 326 PIRSF PIRSF017082 1 325 2.0E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14415 72727beca7c0af37c57ce997271aba1f 47 SUPERFAMILY SSF53098 1 46 1.5E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS14415 72727beca7c0af37c57ce997271aba1f 47 Pfam PF13683 Integrase core domain 1 45 1.4E-19 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK95_RS14415 72727beca7c0af37c57ce997271aba1f 47 Gene3D G3DSA:3.30.420.10 1 46 9.7E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK95_RS06545 8a02c9c4405795e15d82d036677c3575 399 Pfam PF02515 CoA-transferase family III 12 376 8.0E-121 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS06545 8a02c9c4405795e15d82d036677c3575 399 Gene3D G3DSA:3.40.50.10540 10 220 6.5E-110 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS06545 8a02c9c4405795e15d82d036677c3575 399 Gene3D G3DSA:3.40.50.10540 309 398 6.5E-110 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS06545 8a02c9c4405795e15d82d036677c3575 399 SUPERFAMILY SSF89796 11 398 2.09E-131 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS06545 8a02c9c4405795e15d82d036677c3575 399 Gene3D G3DSA:3.30.1540.10 226 308 2.4E-28 T 06-07-2017 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 Gene3D G3DSA:3.50.50.60 252 375 8.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 Gene3D G3DSA:3.50.50.60 6 46 8.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 Gene3D G3DSA:3.50.50.60 100 160 8.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.8E-15 T 06-07-2017 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 132 147 1.8E-15 T 06-07-2017 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 262 277 1.8E-15 T 06-07-2017 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 293 1.8E-15 T 06-07-2017 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 SUPERFAMILY SSF51905 5 153 5.96E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 SUPERFAMILY SSF51905 249 336 5.96E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01005 846534799fada5ff8f265344bbf61e9d 385 Pfam PF01494 FAD binding domain 135 297 1.2E-11 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS13540 c1a95bf60a5b4eca21f453908e4ee5bb 212 Gene3D G3DSA:1.10.357.10 9 199 7.8E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS13540 c1a95bf60a5b4eca21f453908e4ee5bb 212 SUPERFAMILY SSF46689 9 73 8.21E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS16130 3b3edb6dab2808573c853633d04b01aa 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 279 7.1E-27 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS27655 3fec2ea40042a3fe33b22744c66fa1b7 143 SUPERFAMILY SSF54427 18 133 1.38E-13 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS27655 3fec2ea40042a3fe33b22744c66fa1b7 143 Gene3D G3DSA:3.10.450.50 15 133 1.1E-8 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS17230 e33fa07eb5da0833264ce1cd0f2a1659 109 SUPERFAMILY SSF103481 5 104 3.14E-20 T 06-07-2017 CAK95_RS17230 e33fa07eb5da0833264ce1cd0f2a1659 109 Pfam PF00893 Small Multidrug Resistance protein 2 93 2.1E-28 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAK95_RS08940 915ff6a7d17f33391423580248e1f68d 100 SUPERFAMILY SSF54909 1 95 4.02E-31 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS08940 915ff6a7d17f33391423580248e1f68d 100 Pfam PF07045 Domain of unknown function (DUF1330) 3 95 1.2E-33 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 CAK95_RS08940 915ff6a7d17f33391423580248e1f68d 100 Gene3D G3DSA:3.30.70.900 1 96 1.4E-34 T 06-07-2017 CAK95_RS06410 f972b55e5f66f7542833c93e3ea0b6d5 377 SUPERFAMILY SSF55909 21 377 1.47E-106 T 06-07-2017 CAK95_RS06410 f972b55e5f66f7542833c93e3ea0b6d5 377 Gene3D G3DSA:3.75.10.10 21 377 8.6E-138 T 06-07-2017 CAK95_RS17820 9832c86b36571fe42bbcfd2ea95c5ebc 78 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.0E-8 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS17820 9832c86b36571fe42bbcfd2ea95c5ebc 78 Gene3D G3DSA:3.30.70.920 5 77 4.3E-20 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS17820 9832c86b36571fe42bbcfd2ea95c5ebc 78 SUPERFAMILY SSF54909 2 77 5.5E-15 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS14195 26abef2a30887feaca6749b5399e965d 341 SUPERFAMILY SSF144052 12 332 1.28E-15 T 06-07-2017 CAK95_RS09815 f22cfbd94ef96d71eb7cf3210ef86009 67 Gene3D G3DSA:1.10.1470.10 1 64 1.1E-30 T 06-07-2017 IPR008462 CsbD-like CAK95_RS09815 f22cfbd94ef96d71eb7cf3210ef86009 67 SUPERFAMILY SSF69047 1 65 2.62E-26 T 06-07-2017 IPR008462 CsbD-like CAK95_RS09815 f22cfbd94ef96d71eb7cf3210ef86009 67 PIRSF PIRSF039008 1 66 1.4E-30 T 06-07-2017 IPR026042 Stress response protein YjbJ CAK95_RS09815 f22cfbd94ef96d71eb7cf3210ef86009 67 Pfam PF05532 CsbD-like 4 56 6.4E-23 T 06-07-2017 IPR008462 CsbD-like CAK95_RS10225 2b8086519abf3006a6736f09d3a8f4e9 376 Pfam PF02515 CoA-transferase family III 6 364 5.0E-101 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS10225 2b8086519abf3006a6736f09d3a8f4e9 376 SUPERFAMILY SSF89796 4 370 7.85E-106 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS10225 2b8086519abf3006a6736f09d3a8f4e9 376 Gene3D G3DSA:3.40.50.10540 304 373 1.3E-86 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS10225 2b8086519abf3006a6736f09d3a8f4e9 376 Gene3D G3DSA:3.40.50.10540 3 214 1.3E-86 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS10225 2b8086519abf3006a6736f09d3a8f4e9 376 Gene3D G3DSA:3.30.1540.10 220 303 9.9E-25 T 06-07-2017 CAK95_RS05815 ea07d1ae1fb2bf1ba3435f63b205a98d 278 SUPERFAMILY SSF52266 75 264 7.66E-32 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05815 ea07d1ae1fb2bf1ba3435f63b205a98d 278 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 80 248 3.6E-12 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS05815 ea07d1ae1fb2bf1ba3435f63b205a98d 278 Gene3D G3DSA:3.40.50.1110 75 263 2.8E-30 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS06695 b20ac7c4fdea785ca6757748c6beee63 290 Gene3D G3DSA:3.90.1720.10 152 283 4.1E-29 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS06695 b20ac7c4fdea785ca6757748c6beee63 290 Gene3D G3DSA:2.30.30.40 59 92 1.9E-7 T 06-07-2017 CAK95_RS06695 b20ac7c4fdea785ca6757748c6beee63 290 SUPERFAMILY SSF54001 149 284 1.37E-33 T 06-07-2017 CAK95_RS06695 b20ac7c4fdea785ca6757748c6beee63 290 SUPERFAMILY SSF50044 59 97 1.0E-8 T 06-07-2017 IPR001452 SH3 domain GO:0005515 CAK95_RS06695 b20ac7c4fdea785ca6757748c6beee63 290 Pfam PF00877 NlpC/P60 family 172 264 1.4E-12 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS26560 2446951c0ab168afa211688c13ee0f86 268 Pfam PF04909 Amidohydrolase 9 245 7.7E-34 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS26560 2446951c0ab168afa211688c13ee0f86 268 SUPERFAMILY SSF51556 8 264 3.25E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS26560 2446951c0ab168afa211688c13ee0f86 268 Gene3D G3DSA:3.20.20.140 6 265 7.5E-81 T 06-07-2017 CAK95_RS23880 eff962a4e92fee9c3db880f677cbb233 312 SUPERFAMILY SSF52540 70 222 7.61E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23880 eff962a4e92fee9c3db880f677cbb233 312 Gene3D G3DSA:3.40.50.300 95 243 4.1E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23880 eff962a4e92fee9c3db880f677cbb233 312 Pfam PF05673 Protein of unknown function (DUF815) 58 306 2.4E-107 T 06-07-2017 IPR008533 Domain of unknown function DUF815 CAK95_RS04330 950761d1115145bdaa696db2ac7d1595 324 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 25 305 7.2E-40 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAK95_RS04330 950761d1115145bdaa696db2ac7d1595 324 Gene3D G3DSA:3.20.20.190 20 314 2.6E-70 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS04330 950761d1115145bdaa696db2ac7d1595 324 SUPERFAMILY SSF51695 22 310 5.23E-65 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS00880 0022d431a818770515a8b6bdd756f0b4 206 Pfam PF00510 Cytochrome c oxidase subunit III 22 203 3.9E-13 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00880 0022d431a818770515a8b6bdd756f0b4 206 Gene3D G3DSA:1.20.120.80 24 203 2.1E-46 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS00880 0022d431a818770515a8b6bdd756f0b4 206 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 27 206 1.2E-72 T 06-07-2017 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CAK95_RS00880 0022d431a818770515a8b6bdd756f0b4 206 SUPERFAMILY SSF81452 21 204 1.31E-50 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 Pfam PF01545 Cation efflux family 95 273 2.5E-19 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 SUPERFAMILY SSF55008 6 77 1.02E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 SUPERFAMILY SSF161111 90 273 3.79E-34 T 06-07-2017 CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 Gene3D G3DSA:1.20.1510.10 92 270 5.6E-26 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 Pfam PF00403 Heavy-metal-associated domain 9 68 1.4E-9 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK95_RS19760 854288d6aa3b797140adb1ad0d0bbff3 284 Gene3D G3DSA:3.30.70.100 5 75 1.7E-16 T 06-07-2017 CAK95_RS13745 b7f73c2926d4d1ea60b77886b5048177 325 Pfam PF00174 Oxidoreductase molybdopterin binding domain 106 261 6.4E-27 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS13745 b7f73c2926d4d1ea60b77886b5048177 325 Gene3D G3DSA:3.90.420.10 74 316 4.3E-62 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS13745 b7f73c2926d4d1ea60b77886b5048177 325 SUPERFAMILY SSF56524 77 318 1.44E-79 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS24160 4ba821b018e795eb7ef98ee9b73cbfa2 323 SUPERFAMILY SSF53850 114 287 2.17E-8 T 06-07-2017 CAK95_RS24160 4ba821b018e795eb7ef98ee9b73cbfa2 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 3.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS24160 4ba821b018e795eb7ef98ee9b73cbfa2 323 PIRSF PIRSF017082 1 323 1.0E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS13385 d9f6878cd6f8856a349a45f25ea8f81e 474 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 4.6E-25 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CAK95_RS13385 d9f6878cd6f8856a349a45f25ea8f81e 474 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 447 2.3E-126 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS13385 d9f6878cd6f8856a349a45f25ea8f81e 474 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 9 449 26.501 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAK95_RS13385 d9f6878cd6f8856a349a45f25ea8f81e 474 Pfam PF02601 Exonuclease VII, large subunit 129 446 6.5E-92 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAK95_RS10205 7d0c9e52b96f4db0a60180607e4d972d 262 Gene3D G3DSA:3.50.30.50 3 261 5.7E-60 T 06-07-2017 CAK95_RS10205 7d0c9e52b96f4db0a60180607e4d972d 262 Pfam PF04199 Putative cyclase 6 190 1.8E-34 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS10205 7d0c9e52b96f4db0a60180607e4d972d 262 SUPERFAMILY SSF102198 2 260 3.27E-56 T 06-07-2017 CAK95_RS18105 0907b502ac780b08cddd658988399404 175 Gene3D G3DSA:3.40.50.1240 1 169 1.8E-56 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK95_RS18105 0907b502ac780b08cddd658988399404 175 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 84 3.2E-8 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK95_RS18105 0907b502ac780b08cddd658988399404 175 SUPERFAMILY SSF53254 1 168 4.5E-26 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK95_RS20325 7576535575a496c717bd93337a20ab5d 359 Pfam PF03358 NADPH-dependent FMN reductase 100 305 2.0E-24 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK95_RS20325 7576535575a496c717bd93337a20ab5d 359 SUPERFAMILY SSF52218 255 342 9.54E-26 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS20325 7576535575a496c717bd93337a20ab5d 359 SUPERFAMILY SSF52218 97 228 9.54E-26 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS20325 7576535575a496c717bd93337a20ab5d 359 Gene3D G3DSA:3.40.50.360 99 335 6.3E-30 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS23840 2156c698a800d9e8cc20de6693829a38 53 Pfam PF06568 Domain of unknown function (DUF1127) 7 41 1.5E-13 T 06-07-2017 IPR009506 Protein of unknown function DUF1127 CAK95_RS00610 0fa3e9a014871860460c5d305a21bfc6 199 Pfam PF06938 Protein of unknown function (DUF1285) 43 187 3.7E-56 T 06-07-2017 IPR010707 Protein of unknown function DUF1285 CAK95_RS00610 0fa3e9a014871860460c5d305a21bfc6 199 Gene3D G3DSA:3.10.540.10 11 93 8.7E-36 T 06-07-2017 CAK95_RS00610 0fa3e9a014871860460c5d305a21bfc6 199 PIRSF PIRSF029557 1 199 3.5E-84 T 06-07-2017 IPR010707 Protein of unknown function DUF1285 CAK95_RS00610 0fa3e9a014871860460c5d305a21bfc6 199 Gene3D G3DSA:2.20.70.10 178 196 5.9E-4 T 06-07-2017 CAK95_RS00610 0fa3e9a014871860460c5d305a21bfc6 199 Gene3D G3DSA:2.30.270.10 94 163 9.9E-27 T 06-07-2017 IPR023361 Protein of unknown function DUF1285, beta-roll domain CAK95_RS12420 3600479f599cd6d3b9fa8e85e1d8909f 358 SUPERFAMILY SSF52151 1 76 5.75E-20 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS12420 3600479f599cd6d3b9fa8e85e1d8909f 358 SUPERFAMILY SSF52151 159 285 5.75E-20 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS12420 3600479f599cd6d3b9fa8e85e1d8909f 358 Pfam PF01734 Patatin-like phospholipase 6 254 1.8E-14 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 Pfam PF13361 UvrD-like helicase C-terminal domain 500 560 6.1E-8 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 Gene3D G3DSA:3.40.50.300 492 562 1.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 Pfam PF00580 UvrD/REP helicase N-terminal domain 165 267 7.9E-13 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 Gene3D G3DSA:3.40.50.300 3 269 2.8E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 Pfam PF13245 Part of AAA domain 18 66 7.3E-7 T 06-07-2017 CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 SUPERFAMILY SSF52540 429 467 9.49E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 SUPERFAMILY SSF52540 500 565 9.49E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02675 0773d601735de6bf365a4d94523559e2 594 SUPERFAMILY SSF52540 4 374 9.49E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17240 1a92badb9168a644adc403f06e2ac21e 447 SUPERFAMILY SSF63829 140 205 6.54E-6 T 06-07-2017 CAK95_RS17240 1a92badb9168a644adc403f06e2ac21e 447 SUPERFAMILY SSF63829 86 108 6.54E-6 T 06-07-2017 CAK95_RS17240 1a92badb9168a644adc403f06e2ac21e 447 SUPERFAMILY SSF63829 237 318 6.54E-6 T 06-07-2017 CAK95_RS17240 1a92badb9168a644adc403f06e2ac21e 447 Pfam PF13449 Esterase-like activity of phytase 85 418 1.2E-63 T 06-07-2017 IPR027372 Phytase-like domain CAK95_RS23455 e6b2afee852a29a4a7b07f27f14397b7 152 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 6 152 4.2E-48 T 06-07-2017 IPR016568 Sulphur oxidation, SoxY CAK95_RS23455 e6b2afee852a29a4a7b07f27f14397b7 152 Pfam PF13501 Sulfur oxidation protein SoxY 41 150 2.5E-39 T 06-07-2017 IPR032711 Ig-like SoxY domain CAK95_RS23455 e6b2afee852a29a4a7b07f27f14397b7 152 PIRSF PIRSF010312 1 152 7.7E-52 T 06-07-2017 IPR016568 Sulphur oxidation, SoxY CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 Gene3D G3DSA:3.40.190.10 118 221 1.3E-17 T 06-07-2017 CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 317 4.8E-37 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 Gene3D G3DSA:3.40.190.10 245 319 1.4E-22 T 06-07-2017 CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 Gene3D G3DSA:3.40.190.10 26 105 1.4E-22 T 06-07-2017 CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 SUPERFAMILY SSF53850 26 319 8.0E-44 T 06-07-2017 CAK95_RS01390 bfb41c896fa7bba6965f7d6e01815bf1 336 Pfam PF16868 NMT1-like family 35 317 1.4E-28 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 SUPERFAMILY SSF50249 115 189 2.37E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 Gene3D G3DSA:3.30.160.100 4 112 3.7E-13 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 6 110 1.3E-10 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 SUPERFAMILY SSF69754 5 114 1.96E-13 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 Pfam PF00313 'Cold-shock' DNA-binding domain 127 187 4.5E-6 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK95_RS10475 7a8a1355990f7620bb9e0286fb099fb9 195 Gene3D G3DSA:2.40.50.140 127 190 2.7E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS19100 f246080cc0c6118abaf5a9ff88370fc0 495 Pfam PF10983 Protein of unknown function (DUF2793) 37 123 5.1E-30 T 06-07-2017 IPR021251 Protein of unknown function DUF2793 CAK95_RS19100 f246080cc0c6118abaf5a9ff88370fc0 495 SUPERFAMILY SSF51126 245 478 3.87E-11 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS04705 fca8cdb4549deda032b19af10e9238d5 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 246 4.0E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04705 fca8cdb4549deda032b19af10e9238d5 257 SUPERFAMILY SSF161098 51 236 1.96E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04705 fca8cdb4549deda032b19af10e9238d5 257 Gene3D G3DSA:1.10.3720.10 48 246 9.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26850 9a350ed68663fc1a95d3223af72d2251 290 Gene3D G3DSA:3.90.25.10 217 276 1.3E-26 T 06-07-2017 CAK95_RS26850 9a350ed68663fc1a95d3223af72d2251 290 SUPERFAMILY SSF51735 2 285 9.21E-97 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26850 9a350ed68663fc1a95d3223af72d2251 290 Pfam PF04321 RmlD substrate binding domain 2 287 1.7E-107 T 06-07-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 CAK95_RS26850 9a350ed68663fc1a95d3223af72d2251 290 Gene3D G3DSA:3.40.50.720 1 181 1.5E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26850 9a350ed68663fc1a95d3223af72d2251 290 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 283 5.6E-95 T 06-07-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 CAK95_RS24765 ba2a0610d16a74930049bc7869ffd3fb 156 SUPERFAMILY SSF55729 12 143 1.2E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS24765 ba2a0610d16a74930049bc7869ffd3fb 156 Pfam PF00583 Acetyltransferase (GNAT) family 65 144 1.3E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK95_RS24765 ba2a0610d16a74930049bc7869ffd3fb 156 Gene3D G3DSA:3.40.630.30 12 145 4.0E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS28635 713f4d9af93dc7db98f6bb83f49e6de3 453 Pfam PF01565 FAD binding domain 52 180 2.1E-26 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK95_RS28635 713f4d9af93dc7db98f6bb83f49e6de3 453 SUPERFAMILY SSF56176 6 218 3.22E-35 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK95_RS28635 713f4d9af93dc7db98f6bb83f49e6de3 453 Gene3D G3DSA:3.30.465.10 111 217 7.7E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK95_RS28635 713f4d9af93dc7db98f6bb83f49e6de3 453 Gene3D G3DSA:3.30.43.10 8 105 5.3E-15 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK95_RS12505 3c62f4d3b1de891516dcdee004d63566 349 Gene3D G3DSA:3.40.190.10 141 251 3.1E-5 T 06-07-2017 CAK95_RS12505 3c62f4d3b1de891516dcdee004d63566 349 Pfam PF09084 NMT1/THI5 like 53 260 3.5E-16 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS12505 3c62f4d3b1de891516dcdee004d63566 349 SUPERFAMILY SSF53850 46 262 3.15E-28 T 06-07-2017 CAK95_RS08710 c008f734b2cada411254afcc8257a7bd 353 PIRSF PIRSF017082 23 353 4.3E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08710 c008f734b2cada411254afcc8257a7bd 353 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 78 349 1.3E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08710 c008f734b2cada411254afcc8257a7bd 353 SUPERFAMILY SSF53850 142 313 5.43E-15 T 06-07-2017 CAK95_RS11120 47a183e87dbc2602254d840b36ddcf1e 387 Hamap MF_00188 Protease HtpX [htpX]. 14 317 23.699 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAK95_RS11120 47a183e87dbc2602254d840b36ddcf1e 387 Gene3D G3DSA:3.30.2010.10 93 180 3.6E-30 T 06-07-2017 CAK95_RS11120 47a183e87dbc2602254d840b36ddcf1e 387 Pfam PF01435 Peptidase family M48 99 317 7.0E-33 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS18900 b4e6e045bf15a641bf01f46317e9d1a5 190 Pfam PF03692 Putative zinc- or iron-chelating domain 56 124 3.3E-8 T 06-07-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein CAK95_RS18900 b4e6e045bf15a641bf01f46317e9d1a5 190 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 34 180 42.931 T 06-07-2017 IPR008228 Uncharacterised conserved protein UCP006173 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 SUPERFAMILY SSF63380 6 98 2.33E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 Pfam PF00175 Oxidoreductase NAD-binding domain 112 228 1.9E-9 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 SUPERFAMILY SSF52343 103 255 7.86E-39 T 06-07-2017 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 1.8E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 1.8E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 1.8E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 1.8E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 Pfam PF00970 Oxidoreductase FAD-binding domain 19 89 2.8E-5 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 Gene3D G3DSA:3.40.50.80 97 256 1.1E-43 T 06-07-2017 CAK95_RS16570 bd14f50fef6d5e06adf0cb6f17c92407 257 Gene3D G3DSA:2.40.30.10 4 92 1.4E-29 T 06-07-2017 CAK95_RS11065 56ea52cfca6696d33fc57bc694312b1b 164 Pfam PF04120 Low affinity iron permease 35 156 6.9E-48 T 06-07-2017 IPR007251 Low affinity iron permease, Fet4 GO:0055085 CAK95_RS25050 63e4401d504990463e422b96caffe300 471 Gene3D G3DSA:2.70.70.10 318 460 3.4E-48 T 06-07-2017 CAK95_RS25050 63e4401d504990463e422b96caffe300 471 SUPERFAMILY SSF51261 326 459 1.83E-51 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS25050 63e4401d504990463e422b96caffe300 471 Pfam PF01551 Peptidase family M23 361 455 1.7E-31 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS22575 7ba4369b28b7ebc12154285dcb88bd1c 406 Gene3D G3DSA:3.40.50.2000 191 380 2.8E-13 T 06-07-2017 CAK95_RS22575 7ba4369b28b7ebc12154285dcb88bd1c 406 Pfam PF00534 Glycosyl transferases group 1 214 381 7.5E-11 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS22575 7ba4369b28b7ebc12154285dcb88bd1c 406 SUPERFAMILY SSF53756 105 398 2.23E-32 T 06-07-2017 CAK95_RS24975 7f7aa8d42e84bbfd7a700a50c83f8557 141 SUPERFAMILY SSF54593 6 138 1.48E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS24975 7f7aa8d42e84bbfd7a700a50c83f8557 141 Gene3D G3DSA:3.10.180.10 7 139 1.3E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS24975 7f7aa8d42e84bbfd7a700a50c83f8557 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 132 5.1E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS23335 811dd0019af4b4864ff799d21b4bc40b 288 Pfam PF03330 Lytic transglycolase 84 173 3.7E-24 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS23335 811dd0019af4b4864ff799d21b4bc40b 288 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 86 182 1.2E-40 T 06-07-2017 IPR012997 Rare lipoprotein A CAK95_RS23335 811dd0019af4b4864ff799d21b4bc40b 288 Gene3D G3DSA:2.40.40.10 123 175 9.6E-4 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS23335 811dd0019af4b4864ff799d21b4bc40b 288 SUPERFAMILY SSF50685 80 176 4.55E-10 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS00275 58dc7e678d51448d13526bdcf39ed08d 244 SUPERFAMILY SSF52540 5 240 1.67E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00275 58dc7e678d51448d13526bdcf39ed08d 244 Gene3D G3DSA:3.40.50.300 5 237 3.7E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00275 58dc7e678d51448d13526bdcf39ed08d 244 SMART SM00382 30 217 9.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS00275 58dc7e678d51448d13526bdcf39ed08d 244 Pfam PF00005 ABC transporter 22 168 1.6E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28170 7fc9f7d9778749865a1a9bf16643455c 268 SUPERFAMILY SSF53850 12 229 1.09E-8 T 06-07-2017 CAK95_RS28170 7fc9f7d9778749865a1a9bf16643455c 268 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 16 250 5.8E-25 T 06-07-2017 CAK95_RS06505 9936dc05d57a87eb417a223376116f6e 339 SUPERFAMILY SSF51679 7 332 1.16E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS06505 9936dc05d57a87eb417a223376116f6e 339 Gene3D G3DSA:3.20.20.30 2 339 3.5E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS06505 9936dc05d57a87eb417a223376116f6e 339 Pfam PF00296 Luciferase-like monooxygenase 8 255 1.2E-24 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS11445 959f1501f3386144b72aabe3b097aa5a 474 SUPERFAMILY SSF103378 16 459 9.02E-104 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS11445 959f1501f3386144b72aabe3b097aa5a 474 Gene3D G3DSA:3.30.1330.120 281 422 4.8E-22 T 06-07-2017 CAK95_RS11445 959f1501f3386144b72aabe3b097aa5a 474 Pfam PF03972 MmgE/PrpD family 18 454 4.7E-107 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS04545 59538d4487ec8a90a479d2387970fe9e 344 Gene3D G3DSA:3.20.20.30 2 340 7.1E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS04545 59538d4487ec8a90a479d2387970fe9e 344 SUPERFAMILY SSF51679 7 338 2.62E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS04545 59538d4487ec8a90a479d2387970fe9e 344 Pfam PF00296 Luciferase-like monooxygenase 22 304 4.8E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS04545 59538d4487ec8a90a479d2387970fe9e 344 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 6 338 2.1E-155 T 06-07-2017 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative CAK95_RS15620 f6500db9541d99e584b7b4ac01f4dc9c 256 Gene3D G3DSA:3.20.20.60 3 253 3.7E-60 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS15620 f6500db9541d99e584b7b4ac01f4dc9c 256 SUPERFAMILY SSF51621 5 253 2.29E-57 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS15620 f6500db9541d99e584b7b4ac01f4dc9c 256 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 30 242 2.0E-30 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS04260 be46c376200c5aaa775a38b4e57240bf 160 SUPERFAMILY SSF52833 1 160 2.52E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS04260 be46c376200c5aaa775a38b4e57240bf 160 Pfam PF08534 Redoxin 4 157 1.7E-35 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK95_RS04260 be46c376200c5aaa775a38b4e57240bf 160 Gene3D G3DSA:3.40.30.10 1 160 3.7E-59 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Gene3D G3DSA:3.40.30.10 14 171 5.6E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 SUPERFAMILY SSF52833 13 170 1.23E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 183 603 20.652 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Gene3D G3DSA:1.20.1530.10 186 422 3.7E-128 T 06-07-2017 IPR023171 Na/H antiporter domain CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Gene3D G3DSA:1.20.1530.10 465 600 3.7E-128 T 06-07-2017 IPR023171 Na/H antiporter domain CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Pfam PF13462 Thioredoxin 18 165 3.7E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 192 597 1.7E-114 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS12575 a07c2262a9d4e2c83149afb3b07789ea 621 Pfam PF06965 Na+/H+ antiporter 1 190 597 1.1E-128 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PIRSF PIRSF005419 14 707 1.3E-237 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 Pfam PF00771 FHIPEP family 39 698 2.7E-257 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 29 707 7.6E-272 T 06-07-2017 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 83 102 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 46 59 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 199 216 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 250 264 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 169 187 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS15265 3c486ddd878464824ebfc6f10e1b13a9 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 150 166 7.5E-53 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAK95_RS27815 593a6d5e05f861209aea020948762844 438 Pfam PF01425 Amidase 5 418 7.0E-91 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS27815 593a6d5e05f861209aea020948762844 438 Gene3D G3DSA:3.90.1300.10 2 432 6.9E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS27815 593a6d5e05f861209aea020948762844 438 SUPERFAMILY SSF75304 2 430 1.44E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK95_RS11895 43952f59245c89b2da4a66e7b50f772f 86 SUPERFAMILY SSF47336 10 84 5.76E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS11895 43952f59245c89b2da4a66e7b50f772f 86 Pfam PF00550 Phosphopantetheine attachment site 24 80 3.2E-4 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS11895 43952f59245c89b2da4a66e7b50f772f 86 Gene3D G3DSA:1.10.1200.10 9 84 9.3E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK95_RS14080 5d80ad33f8c9f65ac3cd486ecdbc4bf2 131 Gene3D G3DSA:3.10.129.10 7 126 1.9E-42 T 06-07-2017 IPR029069 HotDog domain CAK95_RS14080 5d80ad33f8c9f65ac3cd486ecdbc4bf2 131 SUPERFAMILY SSF54637 7 127 1.09E-41 T 06-07-2017 IPR029069 HotDog domain CAK95_RS14080 5d80ad33f8c9f65ac3cd486ecdbc4bf2 131 Pfam PF03061 Thioesterase superfamily 24 92 2.1E-19 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS15785 bd2e9f142c76966eed68d13dc100f0eb 390 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 101 358 3.5E-54 T 06-07-2017 IPR019285 Protein of unknown function DUF2336 CAK95_RS13095 891fa49c353b7575c3bffb60a74f49b9 502 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 292 492 5.3E-30 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS13095 891fa49c353b7575c3bffb60a74f49b9 502 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 15 275 2.8E-40 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS27180 4710bb9316c7e3b5e9e57d2159aa4c18 412 Pfam PF07958 Protein of unknown function (DUF1688) 11 412 3.0E-144 T 06-07-2017 IPR012469 Protein of unknown function DUF1688 CAK95_RS26750 766ffb0e5cfa49ce92846aa2a163dcc9 285 Gene3D G3DSA:3.40.50.300 4 269 6.9E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26750 766ffb0e5cfa49ce92846aa2a163dcc9 285 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 32 255 1.9E-67 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAK95_RS26750 766ffb0e5cfa49ce92846aa2a163dcc9 285 SUPERFAMILY SSF52540 61 237 1.19E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26750 766ffb0e5cfa49ce92846aa2a163dcc9 285 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 5 266 1.7E-108 T 06-07-2017 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CAK95_RS26750 766ffb0e5cfa49ce92846aa2a163dcc9 285 PIRSF PIRSF028756 5 284 1.8E-68 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAK95_RS03300 d772f23c9ac194fd3247ce1924cc93cb 490 SUPERFAMILY SSF53720 5 482 1.57E-156 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS03300 d772f23c9ac194fd3247ce1924cc93cb 490 Gene3D G3DSA:3.40.309.10 265 443 4.8E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS03300 d772f23c9ac194fd3247ce1924cc93cb 490 Pfam PF00171 Aldehyde dehydrogenase family 17 478 5.5E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS03300 d772f23c9ac194fd3247ce1924cc93cb 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS03300 d772f23c9ac194fd3247ce1924cc93cb 490 Gene3D G3DSA:3.40.605.10 8 264 7.7E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS20890 c9f80d2b5ebea2576841262950e4f590 182 Gene3D G3DSA:3.40.50.2300 7 129 1.2E-32 T 06-07-2017 CAK95_RS20890 c9f80d2b5ebea2576841262950e4f590 182 SUPERFAMILY SSF52172 8 130 1.99E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS20890 c9f80d2b5ebea2576841262950e4f590 182 SMART SM00448 10 126 1.3E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS20890 c9f80d2b5ebea2576841262950e4f590 182 Pfam PF00072 Response regulator receiver domain 13 126 6.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 Gene3D G3DSA:3.40.50.720 432 682 3.1E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 SUPERFAMILY SSF53639 25 227 2.94E-32 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 SMART SM01007 28 227 3.8E-35 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 SUPERFAMILY SSF51735 433 682 1.1E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 Gene3D G3DSA:3.40.225.10 27 227 4.2E-33 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 584 603 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 605 622 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 510 521 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 439 456 5.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 30 225 4.6E-27 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK95_RS25145 325f57ae6101f9f411b58204d2d02976 686 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 446 679 3.8E-40 T 06-07-2017 CAK95_RS10710 b00a6ce4ce7f134ad6132c6591b29848 449 SUPERFAMILY SSF53822 72 434 1.11E-63 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS10710 b00a6ce4ce7f134ad6132c6591b29848 449 Pfam PF13458 Periplasmic binding protein 73 430 2.5E-50 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS10710 b00a6ce4ce7f134ad6132c6591b29848 449 Gene3D G3DSA:3.40.50.2300 72 275 6.5E-41 T 06-07-2017 CAK95_RS24800 ec384a200c9159e1b2c1bd6f70fb1e1e 132 SUPERFAMILY SSF161084 3 126 1.57E-24 T 06-07-2017 CAK95_RS24800 ec384a200c9159e1b2c1bd6f70fb1e1e 132 Pfam PF01124 MAPEG family 6 129 1.9E-19 T 06-07-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CAK95_RS24800 ec384a200c9159e1b2c1bd6f70fb1e1e 132 Gene3D G3DSA:1.20.120.550 5 129 4.2E-17 T 06-07-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CAK95_RS12220 ead032a836c2b4191d0e1e377821c6df 252 Gene3D G3DSA:3.40.50.300 3 240 1.1E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS12220 ead032a836c2b4191d0e1e377821c6df 252 SMART SM00382 30 224 1.1E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS12220 ead032a836c2b4191d0e1e377821c6df 252 Pfam PF00005 ABC transporter 21 171 3.9E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS12220 ead032a836c2b4191d0e1e377821c6df 252 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS12220 ead032a836c2b4191d0e1e377821c6df 252 SUPERFAMILY SSF52540 5 241 2.13E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 Gene3D G3DSA:3.20.20.240 28 494 4.4E-204 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 SUPERFAMILY SSF52242 549 711 1.27E-53 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 581 709 5.6E-56 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 371 396 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 Pfam PF02310 B12 binding domain 584 695 1.8E-15 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 SUPERFAMILY SSF51703 25 543 1.39E-215 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 28 548 2.5E-269 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 Gene3D G3DSA:3.40.50.280 548 709 2.1E-65 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK95_RS18710 350a8e0b1225568be00ace2a7d15cf53 718 Pfam PF01642 Methylmalonyl-CoA mutase 30 541 3.7E-231 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK95_RS19620 9ae61c52219c6430a25ffd7af6101763 229 Pfam PF04335 VirB8 protein 23 226 6.2E-69 T 06-07-2017 IPR007430 Bacterial virulence protein VirB8 GO:0016020 CAK95_RS19620 9ae61c52219c6430a25ffd7af6101763 229 SUPERFAMILY SSF54427 94 228 1.01E-27 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS22580 57c73d7fd8e0844d1ac03eac2751ea90 429 Pfam PF04932 O-Antigen ligase 218 358 5.4E-7 T 06-07-2017 IPR007016 O-antigen ligase-related CAK95_RS22150 98f45e75caf080a9eb78d22efa9235c5 221 SUPERFAMILY SSF56784 2 204 7.05E-41 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS22150 98f45e75caf080a9eb78d22efa9235c5 221 Gene3D G3DSA:3.40.50.1000 2 194 8.9E-27 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS22150 98f45e75caf080a9eb78d22efa9235c5 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 179 5.7E-26 T 06-07-2017 IPR023214 HAD-like domain CAK95_RS11245 6164b9e19a8094c4cd69bbed0e69173f 142 Pfam PF07681 DoxX 16 95 5.2E-17 T 06-07-2017 IPR032808 DoxX family CAK95_RS22600 194a48991d1c9a7b6a535a3938da8807 431 Pfam PF13480 Acetyltransferase (GNAT) domain 217 364 2.2E-26 T 06-07-2017 CAK95_RS22600 194a48991d1c9a7b6a535a3938da8807 431 Gene3D G3DSA:3.20.70.20 179 227 8.4E-4 T 06-07-2017 CAK95_RS22600 194a48991d1c9a7b6a535a3938da8807 431 SUPERFAMILY SSF55729 212 381 1.01E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS26085 cda9b9f1b854f5f1c8511a8ec4588065 104 Pfam PF06568 Domain of unknown function (DUF1127) 58 85 1.6E-7 T 06-07-2017 IPR009506 Protein of unknown function DUF1127 CAK95_RS15145 7f90352ea1bb8f67b03bbab708063441 154 Gene3D G3DSA:2.40.50.180 51 95 8.3E-5 T 06-07-2017 CAK95_RS15145 7f90352ea1bb8f67b03bbab708063441 154 Pfam PF01584 CheW-like domain 13 146 1.4E-25 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15145 7f90352ea1bb8f67b03bbab708063441 154 SMART SM00260 9 145 5.5E-24 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS15145 7f90352ea1bb8f67b03bbab708063441 154 SUPERFAMILY SSF50341 6 146 3.27E-31 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS02040 75cf415ff09347bf03869e3b27217b1f 115 SUPERFAMILY SSF54909 10 90 8.05E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 Gene3D G3DSA:2.60.130.10 28 257 2.6E-80 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 SUPERFAMILY SSF49482 26 258 1.31E-80 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 36 257 1.1E-112 T 06-07-2017 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 Pfam PF00775 Dioxygenase 66 249 3.0E-56 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 100 128 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS21130 f1d4c9d3d5575851ddd69e9edf17bdc1 262 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 29 62 8.6E-14 T 06-07-2017 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 Pfam PF00290 Tryptophan synthase alpha chain 9 258 8.3E-92 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 Gene3D G3DSA:3.20.20.70 4 274 7.4E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 269 36.117 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 49 62 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 254 4.4E-77 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK95_RS10970 b2eef8faf5e4a39d2848a43cd06efdf1 279 SUPERFAMILY SSF51366 3 254 1.22E-87 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS13085 6fb2a6f3cac5b787b85c9db479a4afdc 369 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 325 7.2E-34 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS13085 6fb2a6f3cac5b787b85c9db479a4afdc 369 PIRSF PIRSF039026 4 363 6.1E-119 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAK95_RS15205 07e1e262e679ca35b77edbe4f62a0101 262 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 259 40.079 T 06-07-2017 IPR020936 Uncharacterised protein family UPF0176 CAK95_RS15205 07e1e262e679ca35b77edbe4f62a0101 262 SMART SM00450 116 217 9.5E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS15205 07e1e262e679ca35b77edbe4f62a0101 262 Pfam PF00581 Rhodanese-like domain 122 213 4.5E-6 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS15205 07e1e262e679ca35b77edbe4f62a0101 262 Gene3D G3DSA:3.40.250.10 103 229 4.2E-37 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS15205 07e1e262e679ca35b77edbe4f62a0101 262 SUPERFAMILY SSF52821 93 228 1.92E-28 T 06-07-2017 IPR001763 Rhodanese-like domain CAK95_RS16470 aa86e500b2a2b161b2aa3a137589d008 153 Pfam PF00011 Hsp20/alpha crystallin family 43 139 3.5E-20 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAK95_RS16470 aa86e500b2a2b161b2aa3a137589d008 153 Gene3D G3DSA:2.60.40.790 5 139 3.8E-22 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS16470 aa86e500b2a2b161b2aa3a137589d008 153 SUPERFAMILY SSF49764 12 140 1.81E-23 T 06-07-2017 IPR008978 HSP20-like chaperone CAK95_RS27550 411d1336c52fa61592cf6b2b937a5796 160 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 34 150 2.2E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS27550 411d1336c52fa61592cf6b2b937a5796 160 Gene3D G3DSA:3.10.180.10 28 126 7.1E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS27550 411d1336c52fa61592cf6b2b937a5796 160 SUPERFAMILY SSF54593 33 156 7.52E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS11430 b6b61d002297146a858272735201a270 71 Pfam PF13356 Domain of unknown function (DUF4102) 1 45 4.8E-8 T 06-07-2017 IPR025166 Domain of unknown function DUF4102 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 Pfam PF02357 Transcription termination factor nusG 39 146 3.1E-10 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 SUPERFAMILY SSF50104 163 224 2.11E-9 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 Gene3D G3DSA:2.30.30.30 161 224 4.7E-16 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 SUPERFAMILY SSF82679 38 151 3.53E-16 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 PRINTS PR00338 Transcription termination factor NUSG signature 201 217 2.3E-5 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 PRINTS PR00338 Transcription termination factor NUSG signature 97 109 2.3E-5 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK95_RS24490 2ec7f6c5d035f9b784c74049e98d97b3 225 Gene3D G3DSA:3.30.70.940 37 148 6.6E-8 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK95_RS12395 d2fca808603b085ca83f51e5244f889a 348 SUPERFAMILY SSF144052 140 341 1.44E-13 T 06-07-2017 CAK95_RS28500 b533c505bab96736501b99cb88575e3e 248 Pfam PF00005 ABC transporter 24 178 3.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS28500 b533c505bab96736501b99cb88575e3e 248 Gene3D G3DSA:3.40.50.300 6 245 3.0E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28500 b533c505bab96736501b99cb88575e3e 248 SUPERFAMILY SSF52540 7 246 5.97E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28500 b533c505bab96736501b99cb88575e3e 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 8 248 8.1E-113 T 06-07-2017 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CAK95_RS28500 b533c505bab96736501b99cb88575e3e 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.0E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS01365 99fc7550ed163991d7523376102dc80d 96 Pfam PF10048 Predicted integral membrane protein (DUF2282) 34 87 2.8E-24 T 06-07-2017 IPR018740 Protein of unknown function DUF2282, integral membrane CAK95_RS06625 ae6b44a7897f1ea220b9b41fe9926792 191 Pfam PF07811 TadE-like protein 30 70 3.0E-10 T 06-07-2017 IPR012495 TadE-like CAK95_RS06940 7c8794325d115fe6ade2f070578e5427 127 Pfam PF05239 PRC-barrel domain 20 71 7.6E-8 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS06940 7c8794325d115fe6ade2f070578e5427 127 Gene3D G3DSA:2.30.30.240 18 73 1.2E-10 T 06-07-2017 CAK95_RS06940 7c8794325d115fe6ade2f070578e5427 127 SUPERFAMILY SSF50346 13 125 1.37E-21 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS20770 93e95b0b26e0c1cd94f11a088ed04384 189 Pfam PF00881 Nitroreductase family 10 167 1.8E-25 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK95_RS20770 93e95b0b26e0c1cd94f11a088ed04384 189 Gene3D G3DSA:3.40.109.10 2 186 2.5E-42 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS20770 93e95b0b26e0c1cd94f11a088ed04384 189 SUPERFAMILY SSF55469 3 186 5.1E-39 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK95_RS20770 93e95b0b26e0c1cd94f11a088ed04384 189 PIRSF PIRSF000232 1 189 1.2E-62 T 06-07-2017 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CAK95_RS19220 c38b1c3f1635cd0e131eb727470ba45e 170 Pfam PF10029 Predicted periplasmic protein (DUF2271) 22 162 7.2E-53 T 06-07-2017 IPR014469 Protein of unknown function DUF2271 CAK95_RS19220 c38b1c3f1635cd0e131eb727470ba45e 170 PIRSF PIRSF014995 1 170 2.2E-65 T 06-07-2017 IPR014469 Protein of unknown function DUF2271 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 PRINTS PR00069 Aldo-keto reductase signature 33 57 9.0E-42 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 PRINTS PR00069 Aldo-keto reductase signature 120 137 9.0E-42 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 PRINTS PR00069 Aldo-keto reductase signature 89 107 9.0E-42 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 PRINTS PR00069 Aldo-keto reductase signature 154 183 9.0E-42 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 PRINTS PR00069 Aldo-keto reductase signature 191 215 9.0E-42 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 Gene3D G3DSA:3.20.20.100 7 259 1.2E-89 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 SUPERFAMILY SSF51430 7 260 7.73E-82 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS21760 051f37ef0e1c0ff016d946759ded1546 273 Pfam PF00248 Aldo/keto reductase family 14 253 1.6E-44 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 SMART SM00905 8 121 1.8E-44 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 TIGRFAM TIGR00526 folB_dom: FolB domain 6 122 4.6E-26 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 SUPERFAMILY SSF55620 6 123 3.78E-33 T 06-07-2017 CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 Pfam PF02152 Dihydroneopterin aldolase 8 120 6.2E-31 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 6 121 4.2E-33 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK95_RS18745 37999e53a474842e816f6037401dd5ed 123 Gene3D G3DSA:3.30.1130.10 5 123 3.6E-39 T 06-07-2017 CAK95_RS23440 8d497bf5acd8907d484087664e06b701 175 Pfam PF02635 DsrE/DsrF-like family 68 173 1.1E-10 T 06-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein CAK95_RS23440 8d497bf5acd8907d484087664e06b701 175 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 8 32 6.3E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS23440 8d497bf5acd8907d484087664e06b701 175 Gene3D G3DSA:3.40.1260.10 49 173 2.5E-26 T 06-07-2017 IPR027396 DsrEFH-like CAK95_RS23440 8d497bf5acd8907d484087664e06b701 175 SUPERFAMILY SSF75169 49 173 5.41E-18 T 06-07-2017 IPR027396 DsrEFH-like CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 SUPERFAMILY SSF53659 2 352 2.88E-115 T 06-07-2017 CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 Gene3D G3DSA:3.40.718.10 2 352 4.8E-118 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 SMART SM01329 5 349 1.5E-171 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 349 1.3E-87 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK95_RS09550 20d8f0ae0b21e40c5568310704944522 358 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 352 2.2E-169 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CAK95_RS07275 110ede5dd86bf4002652ba8fe622699b 319 SUPERFAMILY SSF82282 2 312 2.62E-56 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS07275 110ede5dd86bf4002652ba8fe622699b 319 Gene3D G3DSA:3.20.20.330 9 312 2.9E-42 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS07275 110ede5dd86bf4002652ba8fe622699b 319 Pfam PF02574 Homocysteine S-methyltransferase 19 311 1.5E-33 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 SUPERFAMILY SSF56524 15 109 5.89E-26 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 Pfam PF00174 Oxidoreductase molybdopterin binding domain 17 104 6.5E-24 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 Gene3D G3DSA:3.90.420.10 16 109 1.5E-25 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 PRINTS PR00407 Eukaryotic molybdopterin domain signature 84 97 8.4E-6 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 PRINTS PR00407 Eukaryotic molybdopterin domain signature 68 81 8.4E-6 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS01505 15330f3026f6ad14519241dc732d3129 115 PRINTS PR00407 Eukaryotic molybdopterin domain signature 51 67 8.4E-6 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAK95_RS28530 fa8ae0b604b794e5d479e62730a0bc4d 303 SUPERFAMILY SSF51730 23 291 6.67E-43 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS28530 fa8ae0b604b794e5d479e62730a0bc4d 303 Pfam PF02219 Methylenetetrahydrofolate reductase 74 230 4.2E-5 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS28530 fa8ae0b604b794e5d479e62730a0bc4d 303 Gene3D G3DSA:3.20.20.220 23 239 4.2E-28 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 SMART SM00411 12 100 2.6E-25 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 PRINTS PR01727 Prokaryotic integration host factor signature 51 66 7.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 PRINTS PR01727 Prokaryotic integration host factor signature 85 99 7.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 PRINTS PR01727 Prokaryotic integration host factor signature 69 82 7.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 Pfam PF00216 Bacterial DNA-binding protein 13 100 3.8E-28 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 SUPERFAMILY SSF47729 13 100 1.18E-26 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS22760 8eb6a2612e19f288e4969f83cf517553 100 Gene3D G3DSA:4.10.520.10 11 100 7.5E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK95_RS12795 e7b9e160c4aa8ba08c636216be1e3242 326 PIRSF PIRSF017082 1 326 3.8E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12795 e7b9e160c4aa8ba08c636216be1e3242 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 4.1E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12795 e7b9e160c4aa8ba08c636216be1e3242 326 SUPERFAMILY SSF53850 114 286 2.85E-11 T 06-07-2017 CAK95_RS04290 aac5f3f2b1e0ae85e1a1b1847cd84f9f 336 Pfam PF02608 Basic membrane protein 32 296 4.9E-38 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CAK95_RS04290 aac5f3f2b1e0ae85e1a1b1847cd84f9f 336 Gene3D G3DSA:3.40.50.2300 29 150 6.9E-32 T 06-07-2017 CAK95_RS04290 aac5f3f2b1e0ae85e1a1b1847cd84f9f 336 Gene3D G3DSA:3.40.50.2300 151 288 4.9E-29 T 06-07-2017 CAK95_RS12275 fccf4bc416ec5e917a6b766c73711366 257 Gene3D G3DSA:3.90.226.10 2 255 9.1E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS12275 fccf4bc416ec5e917a6b766c73711366 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 256 1.5E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS12275 fccf4bc416ec5e917a6b766c73711366 257 SUPERFAMILY SSF52096 2 257 3.37E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS12275 fccf4bc416ec5e917a6b766c73711366 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK95_RS24380 d91ecfa3cde9db4415c892f41d6b230a 225 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 55 125 1.6E-13 T 06-07-2017 CAK95_RS24380 d91ecfa3cde9db4415c892f41d6b230a 225 SUPERFAMILY SSF55166 2 126 6.51E-27 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS24445 17f77232141028a38769b47d65b55d31 125 Pfam PF05521 Phage head-tail joining protein 8 119 6.2E-9 T 06-07-2017 IPR008767 Bacteriophage SPP1, head-tail adaptor CAK95_RS03070 c05a74c79ee57c495b6410b4e4480c82 59 Pfam PF12244 Protein of unknown function (DUF3606) 5 57 3.6E-22 T 06-07-2017 IPR022037 Protein of unknown function DUF3606 CAK95_RS10765 078df9190dfe31541c5e4be34594ffb5 501 Pfam PF02706 Chain length determinant protein 14 204 6.1E-5 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 SUPERFAMILY SSF54373 176 275 6.47E-11 T 06-07-2017 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 Gene3D G3DSA:3.50.50.60 269 348 2.0E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 Gene3D G3DSA:3.50.50.60 2 176 2.0E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 4.2E-14 T 06-07-2017 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 4.2E-14 T 06-07-2017 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.2E-14 T 06-07-2017 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 Pfam PF01494 FAD binding domain 2 341 2.9E-26 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 SUPERFAMILY SSF51905 269 372 4.32E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS16845 ec6dcc96cf993c493c49af124a02ed60 392 SUPERFAMILY SSF51905 1 171 4.32E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS07015 15623aa43f927d9eba2b00bf83e4f0f6 476 Pfam PF00884 Sulfatase 39 358 8.3E-74 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS07015 15623aa43f927d9eba2b00bf83e4f0f6 476 Gene3D G3DSA:3.30.1120.10 395 452 3.5E-12 T 06-07-2017 CAK95_RS07015 15623aa43f927d9eba2b00bf83e4f0f6 476 Gene3D G3DSA:3.40.720.10 38 394 5.6E-108 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS07015 15623aa43f927d9eba2b00bf83e4f0f6 476 SUPERFAMILY SSF53649 38 447 4.51E-114 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS07015 15623aa43f927d9eba2b00bf83e4f0f6 476 ProSitePatterns PS00149 Sulfatases signature 2. 138 148 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK95_RS27310 8d8d5394445af692d156c26b1fd9ab54 165 SUPERFAMILY SSF51182 2 162 3.96E-43 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS27310 8d8d5394445af692d156c26b1fd9ab54 165 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 2 143 4.0E-48 T 06-07-2017 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CAK95_RS27310 8d8d5394445af692d156c26b1fd9ab54 165 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 2 156 8.3E-61 T 06-07-2017 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CAK95_RS27310 8d8d5394445af692d156c26b1fd9ab54 165 Gene3D G3DSA:2.60.120.10 3 100 1.7E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS16165 f2dd93526b674885494155a1616e9071 422 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 20 66 4.2E-14 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CAK95_RS17375 3a78f774fbd98f865735f7fd508cc390 257 SUPERFAMILY SSF47240 11 251 3.85E-84 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK95_RS17375 3a78f774fbd98f865735f7fd508cc390 257 Pfam PF05138 Phenylacetic acid catabolic protein 7 257 6.4E-99 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAK95_RS17375 3a78f774fbd98f865735f7fd508cc390 257 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 19 257 4.6E-95 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CAK95_RS17375 3a78f774fbd98f865735f7fd508cc390 257 PIRSF PIRSF037834 2 257 1.4E-106 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CAK95_RS17375 3a78f774fbd98f865735f7fd508cc390 257 Gene3D G3DSA:1.20.1260.10 10 257 2.0E-100 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS26445 6b42dfb8dfec158bb24e8d4e89c1060c 330 PIRSF PIRSF017082 1 329 3.6E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS26445 6b42dfb8dfec158bb24e8d4e89c1060c 330 SUPERFAMILY SSF53850 119 286 1.41E-10 T 06-07-2017 CAK95_RS26445 6b42dfb8dfec158bb24e8d4e89c1060c 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 9.5E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15095 a00e0cb5c15135624d699a039f6163dc 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 5.3E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS15095 a00e0cb5c15135624d699a039f6163dc 251 Pfam PF00005 ABC transporter 22 176 1.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS15095 a00e0cb5c15135624d699a039f6163dc 251 SUPERFAMILY SSF52540 4 246 6.46E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15095 a00e0cb5c15135624d699a039f6163dc 251 SMART SM00382 30 223 1.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15095 a00e0cb5c15135624d699a039f6163dc 251 Gene3D G3DSA:3.40.50.300 2 245 1.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04505 ea7ecbcfcb0a6c8da9665be5774f1c17 382 SUPERFAMILY SSF102114 24 306 4.84E-54 T 06-07-2017 CAK95_RS04505 ea7ecbcfcb0a6c8da9665be5774f1c17 382 Pfam PF04055 Radical SAM superfamily 34 186 1.2E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS04505 ea7ecbcfcb0a6c8da9665be5774f1c17 382 Gene3D G3DSA:3.20.20.70 23 308 3.1E-46 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS04505 ea7ecbcfcb0a6c8da9665be5774f1c17 382 Pfam PF11946 Domain of unknown function (DUF3463) 194 326 4.8E-61 T 06-07-2017 IPR022563 Domain of unknown function DUF3463 CAK95_RS04505 ea7ecbcfcb0a6c8da9665be5774f1c17 382 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 315 6.4E-167 T 06-07-2017 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH CAK95_RS03770 555b3437771af377283fe0c7e99b83e3 314 SUPERFAMILY SSF161098 113 294 3.27E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03770 555b3437771af377283fe0c7e99b83e3 314 Gene3D G3DSA:1.10.3720.10 111 303 6.4E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03770 555b3437771af377283fe0c7e99b83e3 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 299 1.1E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21890 82082f019117c9316971feed987cc0af 145 Pfam PF07370 Protein of unknown function (DUF1489) 5 145 6.8E-55 T 06-07-2017 IPR008320 Uncharacterised conserved protein UCP032025 CAK95_RS21890 82082f019117c9316971feed987cc0af 145 PIRSF PIRSF032025 1 145 2.3E-68 T 06-07-2017 IPR008320 Uncharacterised conserved protein UCP032025 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.6E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 1.6E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.6E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 Pfam PF00561 alpha/beta hydrolase fold 27 145 4.3E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 SUPERFAMILY SSF53474 4 296 8.68E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 Gene3D G3DSA:3.40.50.1820 3 294 2.5E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00412 Epoxide hydrolase signature 271 293 2.5E-9 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00412 Epoxide hydrolase signature 32 50 2.5E-9 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00412 Epoxide hydrolase signature 114 127 2.5E-9 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS01725 e8ff30a3284e7230302eeb137b706baf 298 PRINTS PR00412 Epoxide hydrolase signature 100 113 2.5E-9 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS01590 442eb97e5f8278351a7d707f4fc2f872 211 Pfam PF06823 Protein of unknown function (DUF1236) 149 211 4.6E-9 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS27255 5639b236873ecbff6a17194854937df9 250 Gene3D G3DSA:3.40.50.300 2 244 5.4E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27255 5639b236873ecbff6a17194854937df9 250 Pfam PF00005 ABC transporter 22 177 1.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27255 5639b236873ecbff6a17194854937df9 250 SUPERFAMILY SSF52540 3 243 2.02E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27255 5639b236873ecbff6a17194854937df9 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 2.5E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS27255 5639b236873ecbff6a17194854937df9 250 SMART SM00382 30 224 2.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS22025 f3dcf85a721b1cbe9f338b8a0679b202 123 SMART SM00448 3 116 2.6E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS22025 f3dcf85a721b1cbe9f338b8a0679b202 123 Gene3D G3DSA:3.40.50.2300 3 121 2.9E-36 T 06-07-2017 CAK95_RS22025 f3dcf85a721b1cbe9f338b8a0679b202 123 SUPERFAMILY SSF52172 3 121 1.24E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS22025 f3dcf85a721b1cbe9f338b8a0679b202 123 Pfam PF00072 Response regulator receiver domain 5 116 1.0E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 Gene3D G3DSA:2.60.120.10 250 406 4.0E-59 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 Gene3D G3DSA:2.60.120.10 32 215 3.7E-60 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 SMART SM00835 255 396 6.3E-28 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 SMART SM00835 76 219 5.4E-16 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 41 406 3.0E-166 T 06-07-2017 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 Pfam PF00190 Cupin 263 393 5.0E-22 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 Pfam PF00190 Cupin 87 213 1.2E-19 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS15455 34897c444344a7f8e4e8b8b78f5d0279 408 SUPERFAMILY SSF51182 43 401 2.98E-91 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 Pfam PF00571 CBS domain 6 52 1.5E-10 T 06-07-2017 IPR000644 CBS domain CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 Pfam PF00571 CBS domain 68 119 8.2E-11 T 06-07-2017 IPR000644 CBS domain CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 SUPERFAMILY SSF54631 1 129 3.54E-31 T 06-07-2017 CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 SMART SM00116 75 123 6.3E-8 T 06-07-2017 IPR000644 CBS domain CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 SMART SM00116 10 57 9.8E-4 T 06-07-2017 IPR000644 CBS domain CAK95_RS05705 997d205e8f78040cfcabe491af966f40 139 Gene3D G3DSA:3.10.580.10 1 119 2.0E-32 T 06-07-2017 CAK95_RS16380 2ab54541c714176f03324e71b16a5322 375 Pfam PF07995 Glucose / Sorbosone dehydrogenase 40 370 2.0E-139 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAK95_RS16380 2ab54541c714176f03324e71b16a5322 375 SUPERFAMILY SSF50952 30 374 6.67E-48 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK95_RS16380 2ab54541c714176f03324e71b16a5322 375 Gene3D G3DSA:2.120.10.30 11 374 8.5E-112 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS13515 294a9362866f433702277042480a5dcd 256 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 252 2.4E-66 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK95_RS13515 294a9362866f433702277042480a5dcd 256 Gene3D G3DSA:3.60.140.10 5 254 1.4E-81 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK95_RS13515 294a9362866f433702277042480a5dcd 256 SUPERFAMILY SSF64438 4 254 5.86E-80 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAK95_RS13515 294a9362866f433702277042480a5dcd 256 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 30 240 6.7E-49 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK95_RS19700 f541f7051e2902386a2310ad2223dde4 139 Gene3D G3DSA:1.20.1260.10 13 136 8.8E-24 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS19700 f541f7051e2902386a2310ad2223dde4 139 Pfam PF03713 Domain of unknown function (DUF305) 84 134 4.1E-12 T 06-07-2017 IPR005183 Domain of unknown function DUF305 CAK95_RS19030 1364e7defbcffcb1602cbd7c10d37ffd 322 Pfam PF03547 Membrane transport protein 8 155 2.2E-23 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAK95_RS19030 1364e7defbcffcb1602cbd7c10d37ffd 322 Pfam PF03547 Membrane transport protein 156 315 3.5E-19 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAK95_RS04595 88332f8e56eac70540cc5fcff2d08120 335 Gene3D G3DSA:3.20.20.110 79 329 3.6E-52 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAK95_RS04595 88332f8e56eac70540cc5fcff2d08120 335 SUPERFAMILY SSF51649 78 328 2.36E-62 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAK95_RS04595 88332f8e56eac70540cc5fcff2d08120 335 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 83 313 1.3E-24 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 SUPERFAMILY SSF58113 501 682 8.5E-7 T 06-07-2017 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 352 1210 2.0E-5 T 06-07-2017 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 371 552 5.6E-7 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 1436 1591 0.081 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 253 422 6.2E-4 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 514 673 4.0E-12 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 677 817 5.0E-4 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 1084 1255 1.0E-8 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 811 983 0.0065 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 227 353 0.012 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 1231 1377 1.1E-4 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 936 1088 0.011 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 290 464 5.4E-7 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 601 766 2.7E-10 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS17970 49264da1b69893ba5742c9fd78a97bfe 1847 Pfam PF01442 Apolipoprotein A1/A4/E domain 997 1170 2.7E-8 T 06-07-2017 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-174800 CAK95_RS06025 216e2c26f34b0fcd48ec2df386f9cb79 195 Pfam PF00072 Response regulator receiver domain 13 127 2.5E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06025 216e2c26f34b0fcd48ec2df386f9cb79 195 SMART SM00448 11 127 4.7E-7 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK95_RS06025 216e2c26f34b0fcd48ec2df386f9cb79 195 SUPERFAMILY SSF52172 9 131 1.2E-22 T 06-07-2017 IPR011006 CheY-like superfamily CAK95_RS06025 216e2c26f34b0fcd48ec2df386f9cb79 195 Gene3D G3DSA:3.40.50.2300 7 128 1.8E-22 T 06-07-2017 CAK95_RS08540 16e1f7d5f5cdef3630367b474b0617d8 224 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 16 205 7.4E-26 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS08540 16e1f7d5f5cdef3630367b474b0617d8 224 SUPERFAMILY SSF88697 16 207 9.94E-47 T 06-07-2017 IPR015947 PUA-like domain CAK95_RS08540 16e1f7d5f5cdef3630367b474b0617d8 224 SMART SM00464 16 210 4.1E-16 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK95_RS23490 78c98b409d843432fc48bd040c089839 350 Pfam PF00753 Metallo-beta-lactamase superfamily 121 319 1.6E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23490 78c98b409d843432fc48bd040c089839 350 Gene3D G3DSA:3.60.15.10 76 346 1.6E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23490 78c98b409d843432fc48bd040c089839 350 SUPERFAMILY SSF56281 74 348 1.09E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS23490 78c98b409d843432fc48bd040c089839 350 SMART SM00849 124 329 1.8E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Gene3D G3DSA:3.30.9.10 71 156 1.2E-49 T 06-07-2017 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Gene3D G3DSA:3.30.9.10 224 327 1.2E-49 T 06-07-2017 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Gene3D G3DSA:3.50.50.60 330 384 2.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Gene3D G3DSA:3.50.50.60 9 68 2.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Gene3D G3DSA:3.50.50.60 157 219 2.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 SUPERFAMILY SSF51905 327 384 4.47E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 SUPERFAMILY SSF51905 9 227 4.47E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 SUPERFAMILY SSF54373 225 327 9.42E-22 T 06-07-2017 CAK95_RS15815 498b5015522e21193654d2186e926e4c 385 Pfam PF01266 FAD dependent oxidoreductase 10 366 2.5E-51 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS07990 c24901c5fcfcceb12f7eb0c57b64448b 246 Pfam PF00977 Histidine biosynthesis protein 3 230 1.8E-79 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAK95_RS07990 c24901c5fcfcceb12f7eb0c57b64448b 246 Gene3D G3DSA:3.20.20.70 3 239 3.8E-84 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS07990 c24901c5fcfcceb12f7eb0c57b64448b 246 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 233 2.1E-79 T 06-07-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAK95_RS07990 c24901c5fcfcceb12f7eb0c57b64448b 246 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 238 35.92 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAK95_RS07990 c24901c5fcfcceb12f7eb0c57b64448b 246 SUPERFAMILY SSF51366 2 237 5.65E-72 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK95_RS16855 8a08d04ad85a06089824b6207ee261ce 144 SUPERFAMILY SSF143744 8 137 5.49E-32 T 06-07-2017 CAK95_RS16855 8a08d04ad85a06089824b6207ee261ce 144 Pfam PF03928 Haem-degrading 13 134 8.2E-28 T 06-07-2017 IPR005624 Haem-degrading CAK95_RS09335 e0814a76415cb30cdd7be95fcf2134dd 130 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 25 121 8.7E-34 T 06-07-2017 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CAK95_RS09335 e0814a76415cb30cdd7be95fcf2134dd 130 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 32 104 3.3E-18 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CAK95_RS09805 4fe53e1f26a7d34cda2074246306d7ca 287 Pfam PF01261 Xylose isomerase-like TIM barrel 29 240 2.7E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS09805 4fe53e1f26a7d34cda2074246306d7ca 287 Gene3D G3DSA:3.20.20.150 13 276 8.8E-48 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS09805 4fe53e1f26a7d34cda2074246306d7ca 287 SUPERFAMILY SSF51658 14 278 1.01E-44 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS24040 67ab2b17da6cc2ee4a1e164812ec8d17 188 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 7 184 30.68 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS24040 67ab2b17da6cc2ee4a1e164812ec8d17 188 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 8 180 7.9E-64 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS24040 67ab2b17da6cc2ee4a1e164812ec8d17 188 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 5 184 4.7E-50 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS24040 67ab2b17da6cc2ee4a1e164812ec8d17 188 SUPERFAMILY SSF50486 3 186 4.87E-62 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAK95_RS24040 67ab2b17da6cc2ee4a1e164812ec8d17 188 Gene3D G3DSA:3.10.300.10 3 186 1.8E-65 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK95_RS07815 c98aa7c2314bd92234b738aac148a0ef 209 SUPERFAMILY SSF81342 17 209 4.0E-38 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK95_RS07815 c98aa7c2314bd92234b738aac148a0ef 209 Gene3D G3DSA:1.20.950.20 19 209 4.4E-49 T 06-07-2017 CAK95_RS07815 c98aa7c2314bd92234b738aac148a0ef 209 Pfam PF01292 Prokaryotic cytochrome b561 20 206 1.9E-25 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAK95_RS07815 c98aa7c2314bd92234b738aac148a0ef 209 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 22 45 1.4E-5 T 06-07-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CAK95_RS07815 c98aa7c2314bd92234b738aac148a0ef 209 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 174 196 1.4E-5 T 06-07-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CAK95_RS22625 93c342bf8fc4fed9f99f8380e801969f 118 SUPERFAMILY SSF159888 6 109 5.49E-22 T 06-07-2017 CAK95_RS22625 93c342bf8fc4fed9f99f8380e801969f 118 Pfam PF08818 Domain of unknown function (DU1801) 19 108 9.5E-8 T 06-07-2017 IPR014922 Domain of unknown function DUF1801 CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 PIRSF PIRSF005624 2 204 1.3E-49 T 06-07-2017 CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 Gene3D G3DSA:3.40.50.300 9 200 5.7E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 SUPERFAMILY SSF52540 4 200 3.51E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 9 201 2.2E-102 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 Hamap MF_01389 Urease accessory protein UreG [ureG]. 7 205 47.045 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAK95_RS17355 e4f63beb4496ec6f4b5735ec50bb6351 206 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 181 5.0E-37 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK95_RS24290 d9b9338c120d8e4385e094b2784775fd 101 Pfam PF04800 ETC complex I subunit conserved region 2 96 1.7E-38 T 06-07-2017 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 CAK95_RS24290 d9b9338c120d8e4385e094b2784775fd 101 Gene3D G3DSA:3.30.160.190 1 79 3.9E-37 T 06-07-2017 CAK95_RS17315 e8c8f9d5a02d75d6f9aa8234b2d919bf 278 Pfam PF01774 UreD urease accessory protein 60 259 6.6E-43 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAK95_RS17315 e8c8f9d5a02d75d6f9aa8234b2d919bf 278 Hamap MF_01384 Urease accessory protein UreD [ureD]. 4 269 24.516 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAK95_RS21275 a70c323742e9126294edfc3192c504fb 99 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK95_RS21275 a70c323742e9126294edfc3192c504fb 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 9 98 20.449 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAK95_RS21275 a70c323742e9126294edfc3192c504fb 99 Gene3D G3DSA:3.30.70.330 7 98 1.8E-33 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 CAK95_RS21275 a70c323742e9126294edfc3192c504fb 99 SUPERFAMILY SSF54189 7 96 5.76E-30 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK95_RS21275 a70c323742e9126294edfc3192c504fb 99 Pfam PF00276 Ribosomal protein L23 10 95 1.9E-29 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAK95_RS22480 7b16a1e2b82db0c220dd3043919c1b4f 327 SUPERFAMILY SSF53850 105 288 5.34E-11 T 06-07-2017 CAK95_RS22480 7b16a1e2b82db0c220dd3043919c1b4f 327 PIRSF PIRSF017082 1 327 6.2E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS22480 7b16a1e2b82db0c220dd3043919c1b4f 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 323 3.7E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14100 92325ae598c0a0a5ce4d89543c5fe81e 133 Pfam PF13430 Domain of unknown function (DUF4112) 23 125 2.2E-34 T 06-07-2017 IPR025187 Protein of unknown function DUF4112 CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 Gene3D G3DSA:3.40.50.720 4 232 1.3E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 Pfam PF00106 short chain dehydrogenase 9 199 4.7E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 SUPERFAMILY SSF51735 4 234 2.73E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS25980 d6c6de7defad322f25b0d9222ce4620c 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS07940 e7fbec9c383fc00d575c58f7ffc2b319 143 SUPERFAMILY SSF54593 2 126 3.3E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS07940 e7fbec9c383fc00d575c58f7ffc2b319 143 Gene3D G3DSA:3.10.180.10 1 124 4.9E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS07940 e7fbec9c383fc00d575c58f7ffc2b319 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 120 1.3E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS11740 807fd9224c225e1c8cdb34bc538d26a1 176 Gene3D G3DSA:3.40.140.10 78 109 1.4E-5 T 06-07-2017 CAK95_RS11740 807fd9224c225e1c8cdb34bc538d26a1 176 Pfam PF14464 Prokaryotic homologs of the JAB domain 14 124 2.7E-12 T 06-07-2017 IPR028090 JAB domain, prokaryotic CAK95_RS11740 807fd9224c225e1c8cdb34bc538d26a1 176 SUPERFAMILY SSF102712 2 106 1.83E-10 T 06-07-2017 CAK95_RS10125 09762e5d6de04550348c33416cf17539 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 273 1.6E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05225 f03a31dc47e4dd227cf7035458bf0d87 316 Pfam PF04773 FecR protein 112 199 1.6E-19 T 06-07-2017 IPR006860 FecR protein CAK95_RS05225 f03a31dc47e4dd227cf7035458bf0d87 316 PIRSF PIRSF018266 9 313 1.6E-73 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAK95_RS05225 f03a31dc47e4dd227cf7035458bf0d87 316 Pfam PF16220 Domain of unknown function (DUF4880) 20 62 2.7E-9 T 06-07-2017 IPR032623 FecR, N-terminal CAK95_RS00615 81e42208ed89bfce31b93b851b6aa73d 335 Gene3D G3DSA:3.40.50.300 38 205 3.2E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00615 81e42208ed89bfce31b93b851b6aa73d 335 Gene3D G3DSA:1.10.8.300 220 330 1.6E-29 T 06-07-2017 CAK95_RS00615 81e42208ed89bfce31b93b851b6aa73d 335 PIRSF PIRSF002849 3 334 4.0E-114 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAK95_RS00615 81e42208ed89bfce31b93b851b6aa73d 335 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 56 189 2.9E-58 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAK95_RS00615 81e42208ed89bfce31b93b851b6aa73d 335 SUPERFAMILY SSF52540 29 311 8.35E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS01060 e4740868caadeb9ce95721d5315719bd 323 PIRSF PIRSF017082 2 321 8.6E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01060 e4740868caadeb9ce95721d5315719bd 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 1.8E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01060 e4740868caadeb9ce95721d5315719bd 323 SUPERFAMILY SSF53850 86 283 2.81E-14 T 06-07-2017 CAK95_RS27970 be885e4065ed8414c265567d688943e1 85 Pfam PF04226 Transglycosylase associated protein 32 80 1.4E-13 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS26715 7a615f415d2a5b47bfd5bfbc8c50727e 314 SUPERFAMILY SSF161098 93 299 2.88E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26715 7a615f415d2a5b47bfd5bfbc8c50727e 314 Gene3D G3DSA:1.10.3720.10 89 309 2.1E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26715 7a615f415d2a5b47bfd5bfbc8c50727e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 3.7E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS20900 096038ebf24640ba827d5fe04871bb3b 110 SUPERFAMILY SSF54913 2 105 4.08E-33 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK95_RS20900 096038ebf24640ba827d5fe04871bb3b 110 Pfam PF03091 CutA1 divalent ion tolerance protein 5 102 2.8E-31 T 06-07-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CAK95_RS20900 096038ebf24640ba827d5fe04871bb3b 110 Gene3D G3DSA:3.30.70.830 2 106 1.6E-35 T 06-07-2017 CAK95_RS00810 bfa71306e266d1dbcc5d5d55dbb493ee 356 Gene3D G3DSA:1.10.1530.10 9 77 3.5E-22 T 06-07-2017 CAK95_RS00810 bfa71306e266d1dbcc5d5d55dbb493ee 356 Gene3D G3DSA:3.30.1370.60 78 280 1.7E-69 T 06-07-2017 CAK95_RS00810 bfa71306e266d1dbcc5d5d55dbb493ee 356 Pfam PF02615 Malate/L-lactate dehydrogenase 11 340 1.5E-111 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS00810 bfa71306e266d1dbcc5d5d55dbb493ee 356 SUPERFAMILY SSF89733 8 349 5.23E-103 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS02950 98f1a439d65c90d2d393260984d53808 360 SUPERFAMILY SSF55874 147 223 1.2E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS02950 98f1a439d65c90d2d393260984d53808 360 Gene3D G3DSA:3.30.565.10 144 236 1.0E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK95_RS08380 bacfe1777f9085f70ebdbbe09cd79e17 473 Pfam PF00083 Sugar (and other) transporter 60 466 6.1E-41 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK95_RS08380 bacfe1777f9085f70ebdbbe09cd79e17 473 Gene3D G3DSA:1.20.1250.20 271 461 1.2E-20 T 06-07-2017 CAK95_RS08380 bacfe1777f9085f70ebdbbe09cd79e17 473 Gene3D G3DSA:1.20.1250.20 32 212 8.1E-30 T 06-07-2017 CAK95_RS08380 bacfe1777f9085f70ebdbbe09cd79e17 473 SUPERFAMILY SSF103473 8 464 2.22E-73 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS20940 0615270c09f60d93c3fb37a9d98984fd 327 SUPERFAMILY SSF53850 117 287 1.43E-8 T 06-07-2017 CAK95_RS20940 0615270c09f60d93c3fb37a9d98984fd 327 PIRSF PIRSF017082 1 326 1.4E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20940 0615270c09f60d93c3fb37a9d98984fd 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 3.8E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07520 1159e3778d6ff52cb6528f53f172828c 225 Gene3D G3DSA:3.40.50.1110 36 214 5.3E-47 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS07520 1159e3778d6ff52cb6528f53f172828c 225 SUPERFAMILY SSF52266 36 214 4.73E-44 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS07520 1159e3778d6ff52cb6528f53f172828c 225 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 199 3.6E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK95_RS07520 1159e3778d6ff52cb6528f53f172828c 225 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 39 49 - T 06-07-2017 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 Gene3D G3DSA:1.10.357.10 4 204 2.3E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 5.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 SUPERFAMILY SSF46689 4 68 5.64E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK95_RS11530 217cf99d73fa590dde31fed83cc1a108 252 SUPERFAMILY SSF48498 82 204 4.89E-33 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK95_RS19485 8cbaac9a434f9a1edbc057480eb97f59 87 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 14 82 1.3E-5 T 06-07-2017 IPR018754 Protein of unknown function DUF2285 CAK95_RS17700 580d4aec7af13186abdc9790e3f2e004 386 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 371 2.3E-74 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAK95_RS17700 580d4aec7af13186abdc9790e3f2e004 386 Gene3D G3DSA:3.40.50.2000 3 214 3.6E-42 T 06-07-2017 CAK95_RS17700 580d4aec7af13186abdc9790e3f2e004 386 Gene3D G3DSA:3.40.50.2000 215 371 3.2E-11 T 06-07-2017 CAK95_RS17700 580d4aec7af13186abdc9790e3f2e004 386 SUPERFAMILY SSF53756 4 372 5.76E-77 T 06-07-2017 CAK95_RS17700 580d4aec7af13186abdc9790e3f2e004 386 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 5 371 1.3E-116 T 06-07-2017 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAK95_RS23350 f03fab3c851ddd72e73b42476b89f078 354 Pfam PF04860 Phage portal protein 76 310 9.7E-14 T 06-07-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein CAK95_RS19545 af1c18372b3906ba2dc983ddf111c6f7 109 Gene3D G3DSA:1.10.10.10 19 73 6.3E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 PIRSF PIRSF006250 26 307 1.7E-92 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 Gene3D G3DSA:3.20.20.70 155 295 6.4E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 45 132 1.8E-24 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 134 304 3.7E-61 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 34 305 3.8E-95 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 SUPERFAMILY SSF54675 27 133 5.49E-29 T 06-07-2017 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 Gene3D G3DSA:3.90.1170.20 26 154 4.2E-46 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAK95_RS00480 dd1865ac6dd01f56e0c37dcb70aff1a2 307 SUPERFAMILY SSF51690 134 305 2.43E-58 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK95_RS24980 5b38bc49a4d928bacebcab6bb94191bf 130 SUPERFAMILY SSF117916 33 128 3.6E-32 T 06-07-2017 CAK95_RS24980 5b38bc49a4d928bacebcab6bb94191bf 130 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 33 130 1.1E-45 T 06-07-2017 IPR014291 SUF system FeS cluster assembly associated CAK95_RS24980 5b38bc49a4d928bacebcab6bb94191bf 130 Pfam PF01883 Domain of unknown function DUF59 35 108 1.5E-21 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAK95_RS11800 7b3a5f9773c67cf82df2e80735e208bf 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 7.4E-93 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS11800 7b3a5f9773c67cf82df2e80735e208bf 328 SUPERFAMILY SSF53850 107 288 2.44E-13 T 06-07-2017 CAK95_RS11800 7b3a5f9773c67cf82df2e80735e208bf 328 PIRSF PIRSF017082 1 326 4.0E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS06710 b2197b664c479ba711db9436c38cdb19 393 Gene3D G3DSA:1.10.3720.10 183 388 7.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06710 b2197b664c479ba711db9436c38cdb19 393 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 73 8.7E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAK95_RS06710 b2197b664c479ba711db9436c38cdb19 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 390 1.1E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06710 b2197b664c479ba711db9436c38cdb19 393 SUPERFAMILY SSF161098 186 372 1.19E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS19795 9efe4b63c5c4b717cc7fb995998f410f 62 Pfam PF06945 Protein of unknown function (DUF1289) 3 49 3.6E-19 T 06-07-2017 IPR010710 Protein of unknown function DUF1289 CAK95_RS10360 f93d38e971762f03a16f6c6a5a0bde1c 142 Gene3D G3DSA:2.60.120.10 3 139 6.3E-55 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS10360 f93d38e971762f03a16f6c6a5a0bde1c 142 SUPERFAMILY SSF51182 3 139 2.06E-57 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS10360 f93d38e971762f03a16f6c6a5a0bde1c 142 Pfam PF06172 Cupin superfamily (DUF985) 8 134 1.8E-50 T 06-07-2017 IPR009327 Cupin domain of unknown function DUF985 CAK95_RS10855 8c02a598bf7ad359421aae41aef8ab3c 41 Gene3D G3DSA:2.10.70.10 4 41 6.9E-18 T 06-07-2017 CAK95_RS10855 8c02a598bf7ad359421aae41aef8ab3c 41 Pfam PF10636 Hemin uptake protein hemP 5 41 2.3E-18 T 06-07-2017 IPR019600 Hemin uptake protein HemP CAK95_RS18540 271465375a234045f1d9fad5697f9b88 178 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 159 9.3E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS12965 dcd30e9d55ffc63ad4ee3d6bc6573434 212 PIRSF PIRSF008159 1 212 1.0E-55 T 06-07-2017 IPR016537 Uncharacterised conserved protein UCP008159, CAK95_RS12965 dcd30e9d55ffc63ad4ee3d6bc6573434 212 Pfam PF06226 Protein of unknown function (DUF1007) 12 212 5.2E-65 T 06-07-2017 IPR010412 Protein of unknown function DUF1007 CAK95_RS20640 bb96017a3db644a7c09f04849551934b 167 Pfam PF00156 Phosphoribosyl transferase domain 14 159 2.0E-18 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS20640 bb96017a3db644a7c09f04849551934b 167 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 6 167 41.258 T 06-07-2017 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 CAK95_RS20640 bb96017a3db644a7c09f04849551934b 167 Gene3D G3DSA:3.40.50.2020 10 160 3.4E-46 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS20640 bb96017a3db644a7c09f04849551934b 167 SUPERFAMILY SSF53271 6 155 8.26E-36 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS10440 396a04846acb22f1ecbc5925552cde6e 243 SUPERFAMILY SSF53271 65 235 1.7E-29 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS10440 396a04846acb22f1ecbc5925552cde6e 243 Gene3D G3DSA:3.40.50.2020 84 237 2.4E-27 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS10440 396a04846acb22f1ecbc5925552cde6e 243 Pfam PF00156 Phosphoribosyl transferase domain 141 234 7.4E-7 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS10925 32d5d84af6e000fe50b01c8a254d6e2f 184 SUPERFAMILY SSF52833 1 183 5.36E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10925 32d5d84af6e000fe50b01c8a254d6e2f 184 Gene3D G3DSA:3.40.30.10 3 183 8.7E-52 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS10925 32d5d84af6e000fe50b01c8a254d6e2f 184 PIRSF PIRSF000239 1 184 1.7E-40 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS10925 32d5d84af6e000fe50b01c8a254d6e2f 184 Pfam PF00578 AhpC/TSA family 4 142 2.7E-25 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS16890 16ccfd5cdaa06aeb477f45e81e6f2dd9 138 Gene3D G3DSA:3.30.1330.40 4 134 2.5E-39 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS16890 16ccfd5cdaa06aeb477f45e81e6f2dd9 138 Pfam PF01042 Endoribonuclease L-PSP 27 132 1.9E-22 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS16890 16ccfd5cdaa06aeb477f45e81e6f2dd9 138 SUPERFAMILY SSF55298 24 134 2.2E-30 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS17360 94320d31ad667ddf47bfdf8176f499d4 239 Pfam PF07848 PaaX-like protein 2 39 5.0E-12 T 06-07-2017 IPR012906 PaaX-like, N-terminal CAK95_RS17360 94320d31ad667ddf47bfdf8176f499d4 239 PIRSF PIRSF020623 1 239 6.1E-57 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CAK95_RS17360 94320d31ad667ddf47bfdf8176f499d4 239 Gene3D G3DSA:1.10.10.10 3 52 9.0E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS17360 94320d31ad667ddf47bfdf8176f499d4 239 Pfam PF08223 PaaX-like protein C-terminal domain 117 206 1.3E-26 T 06-07-2017 IPR013225 PaaX-like, C-terminal CAK95_RS16250 ce3c9c81171b1a2e773a34c91e4d5d3d 146 Pfam PF04134 Protein of unknown function, DUF393 21 129 1.5E-27 T 06-07-2017 IPR007263 Protein of unknown function DUF393 CAK95_RS18590 5ae4c58daec0366fb3e24e0922fc6835 338 SUPERFAMILY SSF53955 85 204 2.14E-29 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS18590 5ae4c58daec0366fb3e24e0922fc6835 338 Pfam PF01464 Transglycosylase SLT domain 92 194 8.0E-18 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS18590 5ae4c58daec0366fb3e24e0922fc6835 338 Gene3D G3DSA:1.10.530.10 89 205 8.9E-30 T 06-07-2017 CAK95_RS08295 7d0f7af2bca9ed2bdb65300facc030b5 304 Pfam PF00892 EamA-like transporter family 23 155 1.2E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS08295 7d0f7af2bca9ed2bdb65300facc030b5 304 Pfam PF00892 EamA-like transporter family 163 293 9.4E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS08295 7d0f7af2bca9ed2bdb65300facc030b5 304 SUPERFAMILY SSF103481 200 299 6.28E-13 T 06-07-2017 CAK95_RS08295 7d0f7af2bca9ed2bdb65300facc030b5 304 SUPERFAMILY SSF103481 67 158 2.48E-12 T 06-07-2017 CAK95_RS01950 a413ab77115900c02447e7913977a5d4 163 Pfam PF11158 Protein of unknown function (DUF2938) 8 156 3.4E-64 T 06-07-2017 IPR021329 Protein of unknown function DUF2938 CAK95_RS19010 ab72d3568d8443dbdf3ee011e46f4783 417 SUPERFAMILY SSF56563 121 415 8.89E-79 T 06-07-2017 CAK95_RS19010 ab72d3568d8443dbdf3ee011e46f4783 417 Pfam PF05065 Phage capsid family 129 414 5.3E-88 T 06-07-2017 IPR024455 Phage capsid CAK95_RS19010 ab72d3568d8443dbdf3ee011e46f4783 417 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 30 414 1.5E-121 T 06-07-2017 IPR006444 Phage major capsid protein, HK97 CAK95_RS11355 cf70751aa00fa37831a2373c7899c8a1 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 328 1.1E-53 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS11355 cf70751aa00fa37831a2373c7899c8a1 331 PIRSF PIRSF017082 3 331 4.5E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20115 2da4ad28839404f650bcb77632ae8375 649 Pfam PF02705 K+ potassium transporter 41 571 9.0E-196 T 06-07-2017 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CAK95_RS20115 2da4ad28839404f650bcb77632ae8375 649 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 32 649 32.454 T 06-07-2017 IPR023051 Potassium uptake protein, low affinity, Kup CAK95_RS24755 16baa76b0a6b5f1b8867843db2d5b1a0 328 Pfam PF09084 NMT1/THI5 like 88 140 7.4E-5 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS24755 16baa76b0a6b5f1b8867843db2d5b1a0 328 SUPERFAMILY SSF53850 6 134 4.79E-34 T 06-07-2017 CAK95_RS24755 16baa76b0a6b5f1b8867843db2d5b1a0 328 SUPERFAMILY SSF53850 163 318 4.79E-34 T 06-07-2017 CAK95_RS24755 16baa76b0a6b5f1b8867843db2d5b1a0 328 Gene3D G3DSA:3.40.190.10 88 243 6.6E-14 T 06-07-2017 CAK95_RS12525 49e29e244388b9bbcb3aaefadc86d740 273 Pfam PF01226 Formate/nitrite transporter 8 257 3.2E-61 T 06-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CAK95_RS12525 49e29e244388b9bbcb3aaefadc86d740 273 Gene3D G3DSA:1.20.1080.10 24 261 1.2E-62 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK95_RS23735 7fec11bf821844bd8b846d38cd449051 306 Gene3D G3DSA:3.40.50.1820 22 299 1.3E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23735 7fec11bf821844bd8b846d38cd449051 306 SUPERFAMILY SSF53474 13 290 7.05E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23735 7fec11bf821844bd8b846d38cd449051 306 Pfam PF12697 Alpha/beta hydrolase family 43 290 3.9E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS06450 47117847bc997a41be270b47355ec1ef 123 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 103 2.7E-21 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK95_RS17775 54def6eac33b5ffebfed6370041a6079 333 SUPERFAMILY SSF51735 8 147 6.1E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17775 54def6eac33b5ffebfed6370041a6079 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 130 1.9E-27 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK95_RS17775 54def6eac33b5ffebfed6370041a6079 333 Gene3D G3DSA:3.40.50.720 8 141 4.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17775 54def6eac33b5ffebfed6370041a6079 333 SUPERFAMILY SSF55347 135 252 6.02E-16 T 06-07-2017 CAK95_RS17775 54def6eac33b5ffebfed6370041a6079 333 Gene3D G3DSA:3.30.360.10 142 315 7.8E-33 T 06-07-2017 CAK95_RS00885 b0a3ab9db7932ca4e791ffa7bc1e5ccf 104 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 15 88 5.4E-15 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CAK95_RS00885 b0a3ab9db7932ca4e791ffa7bc1e5ccf 104 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 11 102 6.8E-32 T 06-07-2017 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CAK95_RS24015 29e407a5a9053c5ef34920e66a57a819 325 Gene3D G3DSA:3.90.226.10 130 324 1.1E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS24015 29e407a5a9053c5ef34920e66a57a819 325 SUPERFAMILY SSF52096 56 322 3.81E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS24015 29e407a5a9053c5ef34920e66a57a819 325 Pfam PF11918 N-terminal domain of Peptidase_S41 in eukaryotic IRBP 43 111 6.0E-6 T 06-07-2017 CAK95_RS24015 29e407a5a9053c5ef34920e66a57a819 325 SMART SM00245 95 311 5.3E-20 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS24015 29e407a5a9053c5ef34920e66a57a819 325 Pfam PF03572 Peptidase family S41 138 309 2.5E-24 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 SUPERFAMILY SSF46911 9 82 3.27E-28 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 30 53 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 PRINTS PR00974 Ribosomal protein S18 family signature 55 69 2.4E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 PRINTS PR00974 Ribosomal protein S18 family signature 69 79 2.4E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 PRINTS PR00974 Ribosomal protein S18 family signature 37 47 2.4E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 PRINTS PR00974 Ribosomal protein S18 family signature 47 54 2.4E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 Gene3D G3DSA:4.10.640.10 17 81 1.3E-31 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 82 1.0E-21 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 Pfam PF01084 Ribosomal protein S18 28 77 1.2E-25 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 13 80 4.8E-30 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS25915 48ed548d8366f45795b8d2f555d58b7a 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 82 21.675 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07625 3129af596c9fc9acaa603b25cce53b97 147 Gene3D G3DSA:3.20.80.10 2 147 6.1E-15 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain CAK95_RS07625 3129af596c9fc9acaa603b25cce53b97 147 SMART SM00871 1 147 1.2E-12 T 06-07-2017 IPR010499 Bacterial transcription activator, effector binding CAK95_RS07625 3129af596c9fc9acaa603b25cce53b97 147 Pfam PF06445 GyrI-like small molecule binding domain 1 146 4.4E-16 T 06-07-2017 IPR029442 GyrI-like small molecule binding domain CAK95_RS07625 3129af596c9fc9acaa603b25cce53b97 147 SUPERFAMILY SSF55136 2 147 2.09E-19 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain CAK95_RS21945 f4b14d383746995f376fe69ff1e50030 580 SUPERFAMILY SSF53300 422 571 1.48E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS21945 f4b14d383746995f376fe69ff1e50030 580 SUPERFAMILY SSF53300 146 204 1.48E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS21945 f4b14d383746995f376fe69ff1e50030 580 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 23 65 7.5E-13 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CAK95_RS21945 f4b14d383746995f376fe69ff1e50030 580 Gene3D G3DSA:3.40.50.410 149 204 2.5E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS21945 f4b14d383746995f376fe69ff1e50030 580 Gene3D G3DSA:3.40.50.410 422 571 2.5E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK95_RS08965 7f0688b6d5724c44e9268e94f5ea89a3 171 Pfam PF10003 Integral membrane protein (DUF2244) 18 157 2.2E-48 T 06-07-2017 IPR019253 Protein of unknown function DUF2244, transmembrane CAK95_RS08965 7f0688b6d5724c44e9268e94f5ea89a3 171 PIRSF PIRSF032162 1 165 2.4E-63 T 06-07-2017 IPR016990 Uncharacterised conserved protein UCP032162, transmembrane CAK95_RS02765 33ad0d73ee3a7a8c87d696e21e1008fd 663 Gene3D G3DSA:2.70.70.10 478 620 5.7E-44 T 06-07-2017 CAK95_RS02765 33ad0d73ee3a7a8c87d696e21e1008fd 663 Pfam PF01551 Peptidase family M23 522 618 2.5E-30 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS02765 33ad0d73ee3a7a8c87d696e21e1008fd 663 SUPERFAMILY SSF51261 399 620 9.94E-60 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS15250 862c09c754ae1e40e200008851fd1469 293 SUPERFAMILY SSF53474 44 279 6.91E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15250 862c09c754ae1e40e200008851fd1469 293 Gene3D G3DSA:3.40.50.1820 18 284 9.8E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 SUPERFAMILY SSF51735 90 333 3.61E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 259 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 261 278 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 230 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 295 315 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 110 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 179 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 Gene3D G3DSA:3.40.50.720 88 333 1.2E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 240 259 1.7E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 179 1.7E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 98 333 1.0E-62 T 06-07-2017 CAK95_RS13235 d1f3d9ab090238029fc0581c8b3b0192 335 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 227 255 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS13425 ad52ddd5ed655693f50ea0aa98950762 450 SUPERFAMILY SSF111283 10 449 2.09E-125 T 06-07-2017 CAK95_RS13425 ad52ddd5ed655693f50ea0aa98950762 450 Pfam PF01523 Putative modulator of DNA gyrase 29 318 5.9E-52 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAK95_RS18215 2d43f62bd099ec68903a43aa76747124 171 Pfam PF03748 Flagellar basal body-associated protein FliL 73 171 2.1E-19 T 06-07-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CAK95_RS10745 914e7d73191b35492a22cdd5a89cea07 320 Pfam PF13489 Methyltransferase domain 95 239 6.4E-18 T 06-07-2017 CAK95_RS10745 914e7d73191b35492a22cdd5a89cea07 320 SUPERFAMILY SSF53335 94 250 2.07E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10745 914e7d73191b35492a22cdd5a89cea07 320 Gene3D G3DSA:3.40.50.150 94 254 8.4E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS27405 c65d539d3f8e251d683e6767c92dd5b7 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 8.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27405 c65d539d3f8e251d683e6767c92dd5b7 308 SUPERFAMILY SSF161098 98 304 2.88E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27405 c65d539d3f8e251d683e6767c92dd5b7 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 74 2.7E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAK95_RS27405 c65d539d3f8e251d683e6767c92dd5b7 308 Gene3D G3DSA:1.10.3720.10 98 301 3.3E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS11585 7826c142ed7932f227b7bc569b7e6a29 429 Gene3D G3DSA:3.40.720.10 2 285 1.5E-33 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS11585 7826c142ed7932f227b7bc569b7e6a29 429 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 288 2.7E-30 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CAK95_RS11585 7826c142ed7932f227b7bc569b7e6a29 429 SUPERFAMILY SSF53649 3 408 2.18E-45 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS28485 6f97a27480466d7f53f0b05db7b8ab06 119 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 48 1.3E-16 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK95_RS28485 6f97a27480466d7f53f0b05db7b8ab06 119 SMART SM00834 1 41 8.3E-14 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK95_RS28485 6f97a27480466d7f53f0b05db7b8ab06 119 Pfam PF09723 Zinc ribbon domain 1 40 5.0E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK95_RS26390 f179b5e5a072dfe6b01125f7569d0289 214 Gene3D G3DSA:3.40.50.360 4 208 1.3E-51 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS26390 f179b5e5a072dfe6b01125f7569d0289 214 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 206 25.16 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAK95_RS26390 f179b5e5a072dfe6b01125f7569d0289 214 SUPERFAMILY SSF52218 7 209 2.79E-42 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS26390 f179b5e5a072dfe6b01125f7569d0289 214 Pfam PF02525 Flavodoxin-like fold 6 202 2.2E-37 T 06-07-2017 IPR003680 Flavodoxin-like fold CAK95_RS14310 e1314a99caa76372ea6bd24300e447b7 145 Gene3D G3DSA:3.10.20.30 57 144 4.7E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS14310 e1314a99caa76372ea6bd24300e447b7 145 SUPERFAMILY SSF54292 54 144 3.67E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS14310 e1314a99caa76372ea6bd24300e447b7 145 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 73 137 1.3E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS03285 4ecb4be127ce26f9954cd0eed9f333b0 133 Pfam PF13452 N-terminal half of MaoC dehydratase 38 107 1.2E-9 T 06-07-2017 CAK95_RS03285 4ecb4be127ce26f9954cd0eed9f333b0 133 SUPERFAMILY SSF54637 7 130 2.4E-12 T 06-07-2017 IPR029069 HotDog domain CAK95_RS03285 4ecb4be127ce26f9954cd0eed9f333b0 133 Gene3D G3DSA:3.10.129.10 37 131 5.5E-8 T 06-07-2017 IPR029069 HotDog domain CAK95_RS13035 4f5b94ba5b9af1317427e84149d9bf6d 227 Pfam PF04298 Putative neutral zinc metallopeptidase 7 226 1.5E-60 T 06-07-2017 IPR007395 Putative neutral zinc metallopeptidase CAK95_RS16885 0aba6513514758297a449213d2a7b48a 342 Gene3D G3DSA:3.40.190.10 129 282 2.6E-40 T 06-07-2017 CAK95_RS16885 0aba6513514758297a449213d2a7b48a 342 Gene3D G3DSA:3.40.190.10 25 116 2.4E-6 T 06-07-2017 CAK95_RS16885 0aba6513514758297a449213d2a7b48a 342 Pfam PF13416 Bacterial extracellular solute-binding protein 43 307 2.4E-30 T 06-07-2017 CAK95_RS16885 0aba6513514758297a449213d2a7b48a 342 SUPERFAMILY SSF53850 24 338 4.66E-64 T 06-07-2017 CAK95_RS17495 6a12d0c14970c69161ea2ce1f69d87a9 101 Pfam PF07045 Domain of unknown function (DUF1330) 2 92 2.5E-23 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 CAK95_RS17495 6a12d0c14970c69161ea2ce1f69d87a9 101 SUPERFAMILY SSF54909 1 91 1.98E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS17495 6a12d0c14970c69161ea2ce1f69d87a9 101 Gene3D G3DSA:3.30.70.900 1 92 1.4E-25 T 06-07-2017 CAK95_RS00295 39a6430093fd9bae256b5dfd3e9c51ad 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 5.8E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS00295 39a6430093fd9bae256b5dfd3e9c51ad 327 SUPERFAMILY SSF53850 111 282 3.15E-8 T 06-07-2017 CAK95_RS00295 39a6430093fd9bae256b5dfd3e9c51ad 327 PIRSF PIRSF017082 1 327 1.1E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20950 af14b15ab0c286bbc9e84b66887608ee 367 Gene3D G3DSA:2.60.120.10 220 364 8.0E-41 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20950 af14b15ab0c286bbc9e84b66887608ee 367 Gene3D G3DSA:2.60.120.10 45 202 3.3E-39 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS20950 af14b15ab0c286bbc9e84b66887608ee 367 Pfam PF07883 Cupin domain 99 171 2.5E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS20950 af14b15ab0c286bbc9e84b66887608ee 367 Pfam PF07883 Cupin domain 271 337 2.7E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS20950 af14b15ab0c286bbc9e84b66887608ee 367 SUPERFAMILY SSF51182 13 360 1.8E-120 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20750 3f687731f411e887caf5d5e791f94f5f 251 SUPERFAMILY SSF144091 11 237 6.28E-32 T 06-07-2017 CAK95_RS20750 3f687731f411e887caf5d5e791f94f5f 251 Pfam PF01694 Rhomboid family 70 234 4.9E-31 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK95_RS20750 3f687731f411e887caf5d5e791f94f5f 251 Gene3D G3DSA:1.20.1540.10 15 236 6.8E-31 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 165 8.2E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 SUPERFAMILY SSF88659 88 167 2.62E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 Pfam PF04542 Sigma-70 region 2 11 77 5.3E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 SUPERFAMILY SSF88946 9 92 1.84E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 Gene3D G3DSA:1.10.1740.10 9 99 7.3E-12 T 06-07-2017 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 Pfam PF08281 Sigma-70, region 4 109 161 1.9E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK95_RS07885 c2335043c289101f84e327825e9484b3 168 Gene3D G3DSA:1.10.10.10 107 166 4.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS05695 7dbaad054b8e94e7e8a59efe8692f77f 246 Pfam PF03741 Integral membrane protein TerC family 18 209 3.4E-53 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK95_RS07060 291ae590b090f877861eadbd527ed20c 359 Gene3D G3DSA:3.60.15.10 28 315 4.6E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS07060 291ae590b090f877861eadbd527ed20c 359 Pfam PF00753 Metallo-beta-lactamase superfamily 48 217 1.8E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS07060 291ae590b090f877861eadbd527ed20c 359 SUPERFAMILY SSF56281 28 308 7.28E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09965 5b3cc2c105c7b51a6335ec715337fd68 255 SMART SM00953 72 210 9.5E-38 T 06-07-2017 IPR014914 RES domain CAK95_RS09965 5b3cc2c105c7b51a6335ec715337fd68 255 Pfam PF08808 RES domain 64 218 6.5E-26 T 06-07-2017 IPR014914 RES domain CAK95_RS22140 12d3e090d303376efdc0132028f04644 275 Pfam PF07681 DoxX 133 215 3.6E-13 T 06-07-2017 IPR032808 DoxX family CAK95_RS08635 82b6c6596ae4daa64278c2c82f80c307 86 Pfam PF04226 Transglycosylase associated protein 34 80 2.4E-14 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS04965 a5deb0680c1f19b1651f41f85cd35af7 268 SUPERFAMILY SSF54593 9 108 2.23E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS04965 a5deb0680c1f19b1651f41f85cd35af7 268 Pfam PF13468 Glyoxalase-like domain 10 182 7.1E-32 T 06-07-2017 IPR025870 Glyoxalase-like domain CAK95_RS04965 a5deb0680c1f19b1651f41f85cd35af7 268 Gene3D G3DSA:3.10.180.10 5 108 1.7E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS18675 f5b43338316b36f072132081a7113624 177 Pfam PF07813 LTXXQ motif family protein 74 163 7.9E-19 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS04955 8dd28d1d891dac126cf1dc6e0fca4ea6 364 Gene3D G3DSA:3.40.50.1100 156 347 1.4E-37 T 06-07-2017 CAK95_RS04955 8dd28d1d891dac126cf1dc6e0fca4ea6 364 SUPERFAMILY SSF53686 35 347 8.12E-70 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS04955 8dd28d1d891dac126cf1dc6e0fca4ea6 364 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 327 2.2E-43 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK95_RS04955 8dd28d1d891dac126cf1dc6e0fca4ea6 364 Gene3D G3DSA:3.40.50.1100 60 155 4.3E-23 T 06-07-2017 CAK95_RS19165 5a3f08da6724a22236d35b8b43611acb 159 SUPERFAMILY SSF82093 29 134 5.1E-36 T 06-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 CAK95_RS19165 5a3f08da6724a22236d35b8b43611acb 159 Gene3D G3DSA:2.40.50.140 25 122 1.7E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK95_RS19165 5a3f08da6724a22236d35b8b43611acb 159 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 32.575 T 06-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 CAK95_RS19165 5a3f08da6724a22236d35b8b43611acb 159 Pfam PF03100 CcmE 3 128 6.8E-44 T 06-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 CAK95_RS13215 9a9be67fc0917cb459c522dabeb86041 160 Pfam PF04138 GtrA-like protein 29 143 1.0E-17 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAK95_RS05685 d73c5bd03f148756bbb5036fbc49b234 664 SUPERFAMILY SSF53448 286 525 4.22E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS05685 d73c5bd03f148756bbb5036fbc49b234 664 Pfam PF13641 Glycosyltransferase like family 2 285 509 8.3E-26 T 06-07-2017 CAK95_RS05685 d73c5bd03f148756bbb5036fbc49b234 664 Gene3D G3DSA:3.90.550.10 283 521 8.0E-18 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS27235 ce22630da35499c6f6f2c5b41b7c8bd2 146 SUPERFAMILY SSF82771 54 125 1.57E-8 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS27235 ce22630da35499c6f6f2c5b41b7c8bd2 146 Pfam PF01541 GIY-YIG catalytic domain 54 124 4.2E-14 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 SUPERFAMILY SSF51905 144 305 1.05E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 Gene3D G3DSA:3.50.50.60 2 108 2.0E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 Gene3D G3DSA:3.50.50.60 109 304 2.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 SUPERFAMILY SSF51905 4 192 4.43E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.2E-22 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 6.2E-22 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 6.2E-22 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.2E-22 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 6.2E-22 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.8E-14 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 7.8E-14 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 7.8E-14 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 7.8E-14 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 375 7.8E-14 T 06-07-2017 CAK95_RS17020 194966e8044634cb6dff9c92c615f436 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 283 1.1E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS10740 ff81e732049c92cfa59ffa7074540a9f 225 Gene3D G3DSA:3.40.50.150 54 135 2.8E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10740 ff81e732049c92cfa59ffa7074540a9f 225 Pfam PF13489 Methyltransferase domain 20 154 3.2E-9 T 06-07-2017 CAK95_RS10740 ff81e732049c92cfa59ffa7074540a9f 225 SUPERFAMILY SSF53335 28 157 2.32E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01135 2c969742208b91ad36f5fb169be4286b 279 Pfam PF01522 Polysaccharide deacetylase 58 162 5.9E-19 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS01135 2c969742208b91ad36f5fb169be4286b 279 Gene3D G3DSA:3.20.20.370 9 274 3.3E-50 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS01135 2c969742208b91ad36f5fb169be4286b 279 SUPERFAMILY SSF88713 9 277 1.53E-45 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS26165 2a8729443720859ff72c057d78e812e9 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 318 5.3E-47 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS05270 f5139cfff0353f5d882c7c4cdb671dac 322 Pfam PF13460 NAD(P)H-binding 13 157 1.0E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05270 f5139cfff0353f5d882c7c4cdb671dac 322 Gene3D G3DSA:3.40.50.720 7 231 1.7E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05270 f5139cfff0353f5d882c7c4cdb671dac 322 SUPERFAMILY SSF51735 8 296 1.2E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21815 23b4526241afb38344ed3ff2df880290 238 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 1 210 1.5E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS21815 23b4526241afb38344ed3ff2df880290 238 SUPERFAMILY SSF56219 1 217 1.31E-39 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS21815 23b4526241afb38344ed3ff2df880290 238 Gene3D G3DSA:3.60.10.10 1 151 4.9E-14 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK95_RS09365 2282b3d8f064391c8404c174e3040f06 194 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 34 167 2.2E-21 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS14105 b9d4602314efc9887ce5b98d40405c05 321 Gene3D G3DSA:3.20.20.140 9 320 2.2E-90 T 06-07-2017 CAK95_RS14105 b9d4602314efc9887ce5b98d40405c05 321 Pfam PF04909 Amidohydrolase 46 320 8.1E-44 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS14105 b9d4602314efc9887ce5b98d40405c05 321 SUPERFAMILY SSF51556 8 320 1.01E-81 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS07420 9692aa18ad61ec2c964a588e9aa8be17 398 ProSitePatterns PS00336 Beta-lactamase class-C active site. 96 103 - T 06-07-2017 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 CAK95_RS07420 9692aa18ad61ec2c964a588e9aa8be17 398 Gene3D G3DSA:3.40.710.10 44 396 3.2E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS07420 9692aa18ad61ec2c964a588e9aa8be17 398 SUPERFAMILY SSF56601 41 396 1.43E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK95_RS07420 9692aa18ad61ec2c964a588e9aa8be17 398 Pfam PF00144 Beta-lactamase 48 393 4.5E-66 T 06-07-2017 IPR001466 Beta-lactamase-related CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 508 1.5E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Pfam PF00501 AMP-binding enzyme 23 424 2.6E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Gene3D G3DSA:3.40.50.980 17 186 4.5E-35 T 06-07-2017 CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Gene3D G3DSA:2.30.38.10 341 418 1.0E-19 T 06-07-2017 CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Gene3D G3DSA:3.30.300.30 419 517 3.1E-25 T 06-07-2017 CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 Gene3D G3DSA:3.40.50.980 187 337 8.1E-25 T 06-07-2017 CAK95_RS27385 155588481fe5b47659be03ad7f4169c1 535 SUPERFAMILY SSF56801 15 520 7.46E-130 T 06-07-2017 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.86 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 Gene3D G3DSA:3.30.230.40 1 88 2.1E-38 T 06-07-2017 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 1.2E-65 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 Gene3D G3DSA:3.30.230.40 90 195 7.8E-33 T 06-07-2017 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 SUPERFAMILY SSF54211 1 85 7.59E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS08005 5f0bb9940e3099977b8b8e1d05a33567 197 SUPERFAMILY SSF54211 88 178 7.59E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK95_RS17165 32f22a8808bc0a4df85a132a267eab89 511 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 438 5.0E-129 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS13295 cd1a54bbf35c296fab8b93046e5de888 145 SUPERFAMILY SSF54637 3 142 3.1E-36 T 06-07-2017 IPR029069 HotDog domain CAK95_RS13295 cd1a54bbf35c296fab8b93046e5de888 145 PRINTS PR01483 Fatty acid synthase signature 46 67 9.1E-5 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK95_RS13295 cd1a54bbf35c296fab8b93046e5de888 145 PRINTS PR01483 Fatty acid synthase signature 24 46 9.1E-5 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK95_RS13295 cd1a54bbf35c296fab8b93046e5de888 145 Gene3D G3DSA:3.10.129.10 6 136 3.9E-40 T 06-07-2017 IPR029069 HotDog domain CAK95_RS13295 cd1a54bbf35c296fab8b93046e5de888 145 Pfam PF01575 MaoC like domain 20 115 7.7E-24 T 06-07-2017 IPR002539 MaoC-like domain CAK95_RS16115 480218b2e4d520e0a7fbba4dbd53f673 243 SUPERFAMILY SSF52540 5 238 7.93E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16115 480218b2e4d520e0a7fbba4dbd53f673 243 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS16115 480218b2e4d520e0a7fbba4dbd53f673 243 SMART SM00382 29 221 1.5E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16115 480218b2e4d520e0a7fbba4dbd53f673 243 Gene3D G3DSA:3.40.50.300 4 234 4.5E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16115 480218b2e4d520e0a7fbba4dbd53f673 243 Pfam PF00005 ABC transporter 21 169 2.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 Gene3D G3DSA:3.40.50.1980 30 184 3.5E-52 T 06-07-2017 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 192 213 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 245 263 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 68 81 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 81 98 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 271 290 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00690 Adhesin family signature 37 55 5.0E-41 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 Gene3D G3DSA:3.40.50.1980 185 306 1.3E-41 T 06-07-2017 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 303 1.1E-76 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 SUPERFAMILY SSF53807 33 306 1.32E-91 T 06-07-2017 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 218 236 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 81 100 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 241 258 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 37 58 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 192 209 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 62 80 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS13610 657ea11118220cdb8311e45371326d04 307 PRINTS PR00691 Adhesin B signature 263 281 1.9E-37 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAK95_RS20735 e786ca9bc59475222b962f10670d2e11 204 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 37 194 1.2E-71 T 06-07-2017 IPR010319 Transglutaminase-like cysteine peptidase, predicted CAK95_RS25710 221a88b6492b5b4c21ac5256aea5b9ac 131 Pfam PF14552 Tautomerase enzyme 38 119 1.6E-31 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAK95_RS25710 221a88b6492b5b4c21ac5256aea5b9ac 131 Gene3D G3DSA:3.30.429.10 5 127 3.3E-42 T 06-07-2017 CAK95_RS25710 221a88b6492b5b4c21ac5256aea5b9ac 131 SUPERFAMILY SSF55331 2 126 1.63E-39 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK95_RS25195 e67378f5f96dff41babaafb36f7a977e 155 Pfam PF07883 Cupin domain 71 136 1.7E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS25195 e67378f5f96dff41babaafb36f7a977e 155 SUPERFAMILY SSF51182 57 143 8.35E-16 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS25195 e67378f5f96dff41babaafb36f7a977e 155 Gene3D G3DSA:2.60.120.10 66 145 3.7E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS05775 1e4e0b03a66d409090a49491ea8ca099 145 Pfam PF09335 SNARE associated Golgi protein 26 140 2.0E-12 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK95_RS05775 1e4e0b03a66d409090a49491ea8ca099 145 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 36 116 5.0E-4 T 06-07-2017 IPR020143 Uncharacterised protein family, RP436 CAK95_RS15645 62f3860227e211546f6b13d1cf00f2a7 298 Gene3D G3DSA:3.40.190.10 91 186 4.3E-7 T 06-07-2017 CAK95_RS15645 62f3860227e211546f6b13d1cf00f2a7 298 SUPERFAMILY SSF53850 45 284 1.13E-19 T 06-07-2017 CAK95_RS15555 57b342dd62e5d787b7ab24dbcd3af2b1 250 SMART SM00382 29 215 2.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS15555 57b342dd62e5d787b7ab24dbcd3af2b1 250 Gene3D G3DSA:3.40.50.300 2 236 6.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15555 57b342dd62e5d787b7ab24dbcd3af2b1 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 238 5.8E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS15555 57b342dd62e5d787b7ab24dbcd3af2b1 250 SUPERFAMILY SSF52540 4 238 6.71E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS15555 57b342dd62e5d787b7ab24dbcd3af2b1 250 Pfam PF00005 ABC transporter 21 166 2.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS20350 ce35a58eca729209afd39ca0ad71781a 149 SUPERFAMILY SSF55961 3 147 1.4E-44 T 06-07-2017 CAK95_RS20350 ce35a58eca729209afd39ca0ad71781a 149 Gene3D G3DSA:3.30.530.20 3 148 1.0E-59 T 06-07-2017 IPR023393 START-like domain CAK95_RS20350 ce35a58eca729209afd39ca0ad71781a 149 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 146 4.6E-43 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 ProSitePatterns PS00080 Multicopper oxidases signature 2. 317 328 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 Pfam PF07731 Multicopper oxidase 218 332 1.9E-22 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 SUPERFAMILY SSF49503 170 330 7.27E-35 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 Pfam PF07732 Multicopper oxidase 86 193 7.5E-38 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 Gene3D G3DSA:2.60.40.420 41 192 4.0E-40 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 Gene3D G3DSA:2.60.40.420 392 415 2.6E-28 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 Gene3D G3DSA:2.60.40.420 226 325 2.6E-28 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS26010 9bc80bade741cef528b5c7c01697aae9 463 SUPERFAMILY SSF49503 52 197 1.12E-39 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS27885 1632be438d04b8e0a3ebd81fcde56d75 234 Pfam PF06299 Protein of unknown function (DUF1045) 66 222 4.8E-50 T 06-07-2017 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAK95_RS27885 1632be438d04b8e0a3ebd81fcde56d75 234 PIRSF PIRSF033328 6 233 7.5E-57 T 06-07-2017 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAK95_RS20495 22b5631af47f5eea151f04cd2c79b146 306 Pfam PF01904 Protein of unknown function DUF72 63 303 1.4E-60 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS20495 22b5631af47f5eea151f04cd2c79b146 306 Gene3D G3DSA:3.20.20.410 41 305 6.3E-77 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS20495 22b5631af47f5eea151f04cd2c79b146 306 SUPERFAMILY SSF117396 45 305 3.53E-72 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAK95_RS01355 bd59102aa156f3a75fcd40f1f5012651 264 Pfam PF09836 Putative DNA-binding domain 13 104 2.3E-22 T 06-07-2017 IPR018640 Putative DNA-binding domain, bacteria CAK95_RS19035 bbf8e44bf25e26852346891759422815 191 TIGRFAM TIGR02215 phage_chp_gp8: phage conserved hypothetical protein, phiE125 gp8 family 1 191 1.8E-59 T 06-07-2017 IPR011738 Phage conserved hypothetical protein CAK95_RS19035 bbf8e44bf25e26852346891759422815 191 Pfam PF05135 Phage gp6-like head-tail connector protein 14 53 4.1E-7 T 06-07-2017 IPR021146 Phage gp6-like head-tail connector protein CAK95_RS19035 bbf8e44bf25e26852346891759422815 191 Pfam PF05135 Phage gp6-like head-tail connector protein 138 187 5.8E-5 T 06-07-2017 IPR021146 Phage gp6-like head-tail connector protein CAK95_RS04160 3e7eb4df0faf4502573e2a867a595193 149 Pfam PF04214 Protein of unknown function, DUF 55 123 2.8E-26 T 06-07-2017 IPR007332 Protein of unknown function DUF411 CAK95_RS23940 908b1e6128a1c4fbe2c027439dd0269e 593 Pfam PF05036 Sporulation related domain 512 591 2.1E-10 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAK95_RS09495 6d18777c16eb8bbb4fd1cff4b4cf7f0c 184 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 5 163 7.3E-48 T 06-07-2017 IPR020761 Uncharacterised protein family UPF0114, bacteria CAK95_RS09495 6d18777c16eb8bbb4fd1cff4b4cf7f0c 184 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 168 71.295 T 06-07-2017 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 CAK95_RS09495 6d18777c16eb8bbb4fd1cff4b4cf7f0c 184 Pfam PF03350 Uncharacterized protein family, UPF0114 12 127 1.7E-34 T 06-07-2017 IPR005134 Uncharacterised protein family UPF0114 CAK95_RS14555 0b450df30afc017c25589488157ef97f 88 Gene3D G3DSA:3.40.47.10 30 72 1.1E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK95_RS14555 0b450df30afc017c25589488157ef97f 88 Pfam PF13467 Ribbon-helix-helix domain 6 68 1.3E-25 T 06-07-2017 IPR027373 Ribbon-helix-helix domain CAK95_RS22645 fe8d2a20a404dff35bb050f0821b1a70 274 Gene3D G3DSA:3.90.226.10 7 214 5.9E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22645 fe8d2a20a404dff35bb050f0821b1a70 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 274 4.3E-58 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS22645 fe8d2a20a404dff35bb050f0821b1a70 274 SUPERFAMILY SSF52096 14 273 1.45E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS22645 fe8d2a20a404dff35bb050f0821b1a70 274 Gene3D G3DSA:1.10.12.10 221 274 5.5E-15 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK95_RS14580 5a5c9eb96e2bcd03d3145cc4bb39636f 193 Pfam PF02417 Chromate transporter 22 180 2.0E-29 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS17000 17571996ed3d308b75e9d550428f8d64 438 Pfam PF13379 NMT1-like family 48 307 1.1E-103 T 06-07-2017 CAK95_RS17000 17571996ed3d308b75e9d550428f8d64 438 Gene3D G3DSA:3.40.190.10 181 286 1.3E-11 T 06-07-2017 CAK95_RS17000 17571996ed3d308b75e9d550428f8d64 438 SUPERFAMILY SSF53850 55 299 3.14E-25 T 06-07-2017 CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 Gene3D G3DSA:3.40.50.720 5 182 7.3E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 279 1.4E-19 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 SUPERFAMILY SSF48179 181 279 2.04E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 SUPERFAMILY SSF51735 4 177 1.02E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 178 1.3E-57 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 PIRSF PIRSF000105 2 299 3.9E-85 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAK95_RS17050 d430a3429ae0fd2767727d88d1985290 299 Gene3D G3DSA:1.10.1040.10 183 279 7.0E-20 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS05410 1dbaadf384b4657f3bed7336ed62dde6 561 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 106 247 3.1E-11 T 06-07-2017 CAK95_RS13130 77d9d665cb92f42a5ce38864536f686a 276 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 219 229 - T 06-07-2017 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CAK95_RS13130 77d9d665cb92f42a5ce38864536f686a 276 SUPERFAMILY SSF54001 26 263 1.86E-23 T 06-07-2017 CAK95_RS13130 77d9d665cb92f42a5ce38864536f686a 276 Gene3D G3DSA:3.90.70.10 16 263 2.1E-21 T 06-07-2017 CAK95_RS13130 77d9d665cb92f42a5ce38864536f686a 276 Pfam PF00112 Papain family cysteine protease 57 263 8.0E-7 T 06-07-2017 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CAK95_RS24575 de05e76d70d7502db8cbb8267a092e9b 117 SUPERFAMILY SSF47413 14 78 1.91E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS24575 de05e76d70d7502db8cbb8267a092e9b 117 Gene3D G3DSA:1.10.260.40 22 76 1.9E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS05745 6242c75e6cdd27a6dc0964939b0e2325 474 PIRSF PIRSF006060 1 458 2.8E-76 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS05745 6242c75e6cdd27a6dc0964939b0e2325 474 Pfam PF13520 Amino acid permease 26 420 1.2E-41 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK95_RS09190 98ae512025cc9b61b2340929388d026e 243 Gene3D G3DSA:3.40.50.150 70 213 1.3E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS09190 98ae512025cc9b61b2340929388d026e 243 Pfam PF02390 Putative methyltransferase 71 234 6.6E-41 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK95_RS09190 98ae512025cc9b61b2340929388d026e 243 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 26 243 26.156 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK95_RS09190 98ae512025cc9b61b2340929388d026e 243 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 69 236 4.3E-34 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK95_RS09190 98ae512025cc9b61b2340929388d026e 243 SUPERFAMILY SSF53335 59 241 4.7E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02530 99b01df8da90fd6d2cc5f526b3f83a07 86 Gene3D G3DSA:1.10.260.40 1 70 4.0E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02530 99b01df8da90fd6d2cc5f526b3f83a07 86 SUPERFAMILY SSF47413 1 70 1.9E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS02530 99b01df8da90fd6d2cc5f526b3f83a07 86 Pfam PF01381 Helix-turn-helix 11 64 1.9E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS02530 99b01df8da90fd6d2cc5f526b3f83a07 86 SMART SM00530 10 65 1.2E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS00255 0f0a05d5725ee83342fc91122ee87fa1 641 Pfam PF09972 Predicted membrane protein (DUF2207) 26 563 2.0E-79 T 06-07-2017 IPR018702 Protein of unknown function DUF2207, membrane CAK95_RS09170 333e34df445204f69bd6c4bd8d0fc0c8 233 SUPERFAMILY SSF55315 104 194 1.27E-8 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK95_RS09170 333e34df445204f69bd6c4bd8d0fc0c8 233 SUPERFAMILY SSF64376 20 106 1.7E-23 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK95_RS09170 333e34df445204f69bd6c4bd8d0fc0c8 233 Pfam PF04296 Protein of unknown function (DUF448) 22 93 2.7E-20 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK95_RS09170 333e34df445204f69bd6c4bd8d0fc0c8 233 Gene3D G3DSA:3.30.1230.10 19 107 5.0E-26 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK95_RS17135 63672483f423f37feade390b46fa9612 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 239 2.2E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17135 63672483f423f37feade390b46fa9612 263 SUPERFAMILY SSF161098 55 242 2.35E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS17135 63672483f423f37feade390b46fa9612 263 Gene3D G3DSA:1.10.3720.10 55 242 8.9E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16640 c53784bfada574f678a8487cf2dff21f 325 SUPERFAMILY SSF53850 27 263 9.66E-27 T 06-07-2017 CAK95_RS16640 c53784bfada574f678a8487cf2dff21f 325 Pfam PF13379 NMT1-like family 24 268 1.3E-13 T 06-07-2017 CAK95_RS16640 c53784bfada574f678a8487cf2dff21f 325 Gene3D G3DSA:3.40.190.10 125 247 7.9E-11 T 06-07-2017 CAK95_RS05160 db6a99deac1937a46d3993f8473b29ef 235 SUPERFAMILY SSF81452 14 235 1.15E-49 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05160 db6a99deac1937a46d3993f8473b29ef 235 Pfam PF00510 Cytochrome c oxidase subunit III 36 235 4.4E-19 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS05160 db6a99deac1937a46d3993f8473b29ef 235 Gene3D G3DSA:1.20.120.80 31 235 1.7E-52 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS17615 73a90bc112846a7ed2f7b509bddf2811 250 SUPERFAMILY SSF53448 1 148 5.87E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17615 73a90bc112846a7ed2f7b509bddf2811 250 Gene3D G3DSA:3.90.550.10 1 100 5.6E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS17615 73a90bc112846a7ed2f7b509bddf2811 250 Pfam PF00535 Glycosyl transferase family 2 5 117 3.6E-15 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS26415 ffc6baab0575418c52f3482b900853e1 603 SUPERFAMILY SSF102114 189 428 5.23E-27 T 06-07-2017 CAK95_RS26415 ffc6baab0575418c52f3482b900853e1 603 Gene3D G3DSA:3.80.30.20 219 414 8.4E-30 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK95_RS26415 ffc6baab0575418c52f3482b900853e1 603 Pfam PF04055 Radical SAM superfamily 226 385 5.8E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK95_RS26415 ffc6baab0575418c52f3482b900853e1 603 SMART SM00729 219 434 1.7E-17 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK95_RS17860 32036d263acdd95e0738c98006f1d3ee 384 Pfam PF06823 Protein of unknown function (DUF1236) 323 383 1.2E-14 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS17860 32036d263acdd95e0738c98006f1d3ee 384 Pfam PF06823 Protein of unknown function (DUF1236) 214 282 3.3E-17 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS03240 30f396c72748ef3699a947540fc1fdf9 116 Pfam PF07439 Protein of unknown function (DUF1515) 9 104 3.4E-8 T 06-07-2017 IPR010889 Protein of unknown function DUF1515 CAK95_RS04935 d3b5f1725b2dcc64aeb256ab089be905 308 Gene3D G3DSA:3.40.190.10 106 223 7.0E-5 T 06-07-2017 CAK95_RS04935 d3b5f1725b2dcc64aeb256ab089be905 308 SUPERFAMILY SSF53850 13 294 2.23E-14 T 06-07-2017 CAK95_RS04935 d3b5f1725b2dcc64aeb256ab089be905 308 Pfam PF09084 NMT1/THI5 like 14 227 1.9E-11 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS13700 2735339107006d5aef0fb78e27d30eaf 307 Pfam PF00005 ABC transporter 21 163 6.7E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS13700 2735339107006d5aef0fb78e27d30eaf 307 SUPERFAMILY SSF52540 3 233 1.11E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS13700 2735339107006d5aef0fb78e27d30eaf 307 SMART SM00382 30 211 4.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS13700 2735339107006d5aef0fb78e27d30eaf 307 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS13700 2735339107006d5aef0fb78e27d30eaf 307 Gene3D G3DSA:3.40.50.300 3 235 1.1E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04130 2ac8acea32f5bdb2aab49402935688c6 129 SUPERFAMILY SSF102829 3 89 8.76E-23 T 06-07-2017 IPR007838 Cell division protein ZapA-like CAK95_RS04130 2ac8acea32f5bdb2aab49402935688c6 129 Pfam PF05164 Cell division protein ZapA 4 116 8.3E-24 T 06-07-2017 IPR007838 Cell division protein ZapA-like CAK95_RS09425 fc5328e3ac3d05fad5807a90b918fda1 319 PIRSF PIRSF017082 1 319 1.1E-63 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS09425 fc5328e3ac3d05fad5807a90b918fda1 319 SUPERFAMILY SSF53850 118 286 4.99E-6 T 06-07-2017 CAK95_RS09425 fc5328e3ac3d05fad5807a90b918fda1 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 314 2.7E-23 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS20505 8c6a0ae46dd5209633135e62356b23a6 153 Pfam PF07883 Cupin domain 46 109 6.6E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS20505 8c6a0ae46dd5209633135e62356b23a6 153 SUPERFAMILY SSF51182 22 148 1.16E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS20505 8c6a0ae46dd5209633135e62356b23a6 153 Gene3D G3DSA:2.60.120.10 46 133 1.6E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS17215 4597ebfaf5c6df6d34137c1979dd6702 136 SUPERFAMILY SSF54637 7 128 4.3E-42 T 06-07-2017 IPR029069 HotDog domain CAK95_RS17215 4597ebfaf5c6df6d34137c1979dd6702 136 Pfam PF03061 Thioesterase superfamily 39 109 3.8E-7 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK95_RS17215 4597ebfaf5c6df6d34137c1979dd6702 136 Gene3D G3DSA:3.10.129.10 5 132 3.1E-44 T 06-07-2017 IPR029069 HotDog domain CAK95_RS17215 4597ebfaf5c6df6d34137c1979dd6702 136 PIRSF PIRSF014972 4 135 5.4E-47 T 06-07-2017 IPR025540 Fluoroacetyl-CoA thioesterase CAK95_RS19075 7100fae919357c814df79d106c43377e 214 TIGRFAM TIGR02217 chp_TIGR02217: TIGR02217 family protein 4 213 8.9E-93 T 06-07-2017 IPR011740 Protein of unknown function DUF2460 CAK95_RS19075 7100fae919357c814df79d106c43377e 214 Pfam PF09343 Conserved hypothetical protein 2217 (DUF2460) 7 213 6.0E-76 T 06-07-2017 IPR011740 Protein of unknown function DUF2460 CAK95_RS02820 d8b69b52fb11602a9705a7797df8703c 160 SMART SM00347 28 129 2.2E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS02820 d8b69b52fb11602a9705a7797df8703c 160 Pfam PF12802 MarR family 33 93 3.1E-17 T 06-07-2017 CAK95_RS02820 d8b69b52fb11602a9705a7797df8703c 160 Gene3D G3DSA:1.10.10.10 7 142 5.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS02820 d8b69b52fb11602a9705a7797df8703c 160 SUPERFAMILY SSF46785 9 142 2.09E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20330 507be05f08656fc9bce6e30835c15a88 129 Gene3D G3DSA:1.20.1290.10 4 127 1.1E-17 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS20330 507be05f08656fc9bce6e30835c15a88 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 1.0E-17 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS20330 507be05f08656fc9bce6e30835c15a88 129 SUPERFAMILY SSF69118 4 126 6.05E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS27115 390328f3776cf4d412b431f220fd06cf 254 Gene3D G3DSA:1.10.3720.10 50 246 1.2E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27115 390328f3776cf4d412b431f220fd06cf 254 SUPERFAMILY SSF161098 53 236 8.5E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS27115 390328f3776cf4d412b431f220fd06cf 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 245 3.1E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS15960 be8d8038f5be2137c5272520c8561414 257 SUPERFAMILY SSF51658 1 253 3.59E-71 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS15960 be8d8038f5be2137c5272520c8561414 257 PIRSF PIRSF006241 1 257 2.2E-86 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CAK95_RS15960 be8d8038f5be2137c5272520c8561414 257 Pfam PF01261 Xylose isomerase-like TIM barrel 22 216 3.5E-28 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS15960 be8d8038f5be2137c5272520c8561414 257 Gene3D G3DSA:3.20.20.150 1 253 5.3E-77 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK95_RS04225 64f2eaff5458ecf2ec9d0e08cdd3de37 64 Pfam PF06698 Protein of unknown function (DUF1192) 6 63 2.8E-25 T 06-07-2017 IPR009579 Protein of unknown function DUF1192 CAK95_RS18690 095e4f4afef81ecd6531cec02efcf16f 266 Pfam PF12570 Protein of unknown function (DUF3750) 65 192 2.4E-44 T 06-07-2017 IPR022224 Protein of unknown function DUF3750 CAK95_RS19635 573c99acc3488fb7b54338105b0e67f9 75 Pfam PF10038 Protein of unknown function (DUF2274) 1 70 4.1E-32 T 06-07-2017 IPR018733 Protein of unknown function DUF2274 CAK95_RS19910 69b0dc9a6f9c4562e96b78e86f70754f 77 Pfam PF02530 Porin subfamily 45 74 2.1E-6 T 06-07-2017 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 CAK95_RS15080 bbfae950ff2563ed14ddca5c379fe636 415 SUPERFAMILY SSF53822 41 390 2.16E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS15080 bbfae950ff2563ed14ddca5c379fe636 415 Gene3D G3DSA:3.40.50.2300 164 339 1.2E-33 T 06-07-2017 CAK95_RS15080 bbfae950ff2563ed14ddca5c379fe636 415 Pfam PF13458 Periplasmic binding protein 41 383 2.5E-57 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS23975 0ef925c2afaca5643b0cf121a5e7e504 375 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 368 9.2E-72 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS23975 0ef925c2afaca5643b0cf121a5e7e504 375 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 288 3.9E-19 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAK95_RS23975 0ef925c2afaca5643b0cf121a5e7e504 375 SUPERFAMILY SSF111369 58 293 2.75E-50 T 06-07-2017 CAK95_RS23975 0ef925c2afaca5643b0cf121a5e7e504 375 Gene3D G3DSA:2.40.50.100 177 211 8.8E-20 T 06-07-2017 CAK95_RS23975 0ef925c2afaca5643b0cf121a5e7e504 375 Gene3D G3DSA:2.40.50.100 69 102 8.8E-20 T 06-07-2017 CAK95_RS23345 0e7e72fbadf2c859081057f0199a4038 187 SUPERFAMILY SSF158668 14 151 2.62E-20 T 06-07-2017 CAK95_RS23345 0e7e72fbadf2c859081057f0199a4038 187 Gene3D G3DSA:1.20.120.330 12 127 8.0E-16 T 06-07-2017 CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 SUPERFAMILY SSF53474 2 265 6.01E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 Pfam PF00561 alpha/beta hydrolase fold 28 162 6.4E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS16345 12ef2606f34f3febda020ce269bf8668 268 Gene3D G3DSA:3.40.50.1820 2 266 1.4E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS17880 617b4de254db2d40789cce6a9e06686c 399 PIRSF PIRSF004925 8 395 9.2E-102 T 06-07-2017 IPR026032 Probable 3-phenylpropionic acid transporter CAK95_RS17880 617b4de254db2d40789cce6a9e06686c 399 SUPERFAMILY SSF103473 15 388 2.75E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS17880 617b4de254db2d40789cce6a9e06686c 399 Pfam PF12832 MFS_1 like family 22 359 2.2E-43 T 06-07-2017 IPR024989 Major facilitator superfamily associated domain CAK95_RS17880 617b4de254db2d40789cce6a9e06686c 399 Gene3D G3DSA:1.20.1250.20 14 189 3.6E-18 T 06-07-2017 CAK95_RS17880 617b4de254db2d40789cce6a9e06686c 399 Gene3D G3DSA:1.20.1250.20 202 380 3.3E-23 T 06-07-2017 CAK95_RS06155 000a2a480b264f6bed3561fc414bab2e 200 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 5 200 1.2E-73 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CAK95_RS06155 000a2a480b264f6bed3561fc414bab2e 200 Pfam PF00775 Dioxygenase 46 181 2.7E-19 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS06155 000a2a480b264f6bed3561fc414bab2e 200 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 54 82 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS06155 000a2a480b264f6bed3561fc414bab2e 200 SUPERFAMILY SSF49482 4 200 8.11E-54 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS06155 000a2a480b264f6bed3561fc414bab2e 200 Gene3D G3DSA:2.60.130.10 4 199 4.9E-61 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS15580 8b51b76ceed9eaa1d501ced43505aaad 247 SUPERFAMILY SSF52218 4 222 2.62E-59 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS15580 8b51b76ceed9eaa1d501ced43505aaad 247 Pfam PF02525 Flavodoxin-like fold 4 209 2.1E-48 T 06-07-2017 IPR003680 Flavodoxin-like fold CAK95_RS15580 8b51b76ceed9eaa1d501ced43505aaad 247 Gene3D G3DSA:3.40.50.360 4 217 8.4E-59 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 Pfam PF03069 Acetamidase/Formamidase family 163 308 1.6E-21 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 Pfam PF03069 Acetamidase/Formamidase family 66 157 1.9E-11 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 Gene3D G3DSA:3.10.28.20 233 312 6.0E-29 T 06-07-2017 CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 SUPERFAMILY SSF141130 7 310 6.15E-88 T 06-07-2017 CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 Gene3D G3DSA:2.60.120.580 143 229 7.7E-56 T 06-07-2017 CAK95_RS28780 b3d2324252d47acac8c28322eaadcbf6 321 Gene3D G3DSA:2.60.120.580 3 95 7.7E-56 T 06-07-2017 CAK95_RS10415 344595feac6810eca960c2d9d94375bd 299 SUPERFAMILY SSF103481 42 147 9.55E-10 T 06-07-2017 CAK95_RS10415 344595feac6810eca960c2d9d94375bd 299 Pfam PF00892 EamA-like transporter family 5 144 1.8E-6 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK95_RS10415 344595feac6810eca960c2d9d94375bd 299 SUPERFAMILY SSF103481 216 298 8.5E-7 T 06-07-2017 CAK95_RS07050 169fb83b265604db0292950e4da70623 562 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 117 127 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS07050 169fb83b265604db0292950e4da70623 562 SUPERFAMILY SSF52016 370 558 1.8E-58 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK95_RS07050 169fb83b265604db0292950e4da70623 562 SUPERFAMILY SSF143975 8 369 1.44E-118 T 06-07-2017 CAK95_RS07050 169fb83b265604db0292950e4da70623 562 Pfam PF00920 Dehydratase family 34 552 2.0E-179 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 SUPERFAMILY SSF55811 2 131 1.62E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 Pfam PF00293 NUDIX domain 9 119 1.4E-23 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 Gene3D G3DSA:3.90.79.10 2 130 9.3E-47 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 PRINTS PR00502 NUDIX hydrolase family signature 49 64 2.1E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS01930 03914317dd26c0d433a5e67e21061ce4 137 PRINTS PR00502 NUDIX hydrolase family signature 35 49 2.1E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK95_RS20715 4bc48d5a9f286f34b152d652d7a0bbec 70 Pfam PF11324 Protein of unknown function (DUF3126) 5 67 3.4E-32 T 06-07-2017 IPR021473 Protein of unknown function DUF3126 CAK95_RS23130 b15d39cd9e9cdda8705bc3e7ed3026ae 291 SUPERFAMILY SSF54593 3 257 1.55E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS23130 b15d39cd9e9cdda8705bc3e7ed3026ae 291 Pfam PF13468 Glyoxalase-like domain 5 192 6.0E-39 T 06-07-2017 IPR025870 Glyoxalase-like domain CAK95_RS23130 b15d39cd9e9cdda8705bc3e7ed3026ae 291 Gene3D G3DSA:3.10.180.10 20 61 4.9E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS23130 b15d39cd9e9cdda8705bc3e7ed3026ae 291 Gene3D G3DSA:3.10.180.10 3 19 3.8E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS23130 b15d39cd9e9cdda8705bc3e7ed3026ae 291 Gene3D G3DSA:3.10.180.10 63 85 3.8E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20105 1ddc308e3a81a5050ab75a2f0422a974 257 Pfam PF01618 MotA/TolQ/ExbB proton channel family 99 211 1.2E-20 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAK95_RS20610 e057271d6223f71acf1160a52b36ddbe 248 Gene3D G3DSA:3.60.20.10 2 209 1.9E-14 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS20610 e057271d6223f71acf1160a52b36ddbe 248 SUPERFAMILY SSF56235 2 242 7.73E-31 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS20610 e057271d6223f71acf1160a52b36ddbe 248 PIRSF PIRSF009120 1 248 3.0E-96 T 06-07-2017 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 CAK95_RS05070 e001f2f8fdcef5b367ce0f033cc71e65 114 Pfam PF06411 HdeA/HdeB family 20 93 8.6E-9 T 06-07-2017 IPR010486 HNS-dependent expression A/B CAK95_RS16195 a4367da13a5d5454c7057e9147be55ca 124 SUPERFAMILY SSF54197 3 109 2.94E-30 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS16195 a4367da13a5d5454c7057e9147be55ca 124 Gene3D G3DSA:3.30.428.10 11 119 3.3E-29 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK95_RS16195 a4367da13a5d5454c7057e9147be55ca 124 Pfam PF01230 HIT domain 11 102 1.2E-19 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK95_RS07055 cc439e5ffed580eea6c8176395cc0787 324 PIRSF PIRSF017082 1 323 7.2E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07055 cc439e5ffed580eea6c8176395cc0787 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.1E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07055 cc439e5ffed580eea6c8176395cc0787 324 SUPERFAMILY SSF53850 115 285 3.8E-10 T 06-07-2017 CAK95_RS14930 060a27e769c25250049ba99e6e616b2d 259 Gene3D G3DSA:1.10.3720.10 59 251 3.0E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14930 060a27e769c25250049ba99e6e616b2d 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 244 1.7E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS14930 060a27e769c25250049ba99e6e616b2d 259 SUPERFAMILY SSF161098 60 239 1.96E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00510 1593e2d01dd6556b5a3ecd907dd40059 47 Pfam PF11295 Protein of unknown function (DUF3096) 10 44 4.5E-18 T 06-07-2017 IPR021446 Protein of unknown function DUF3096 CAK95_RS05905 b97f86e588346e822c82e66990770c89 319 SUPERFAMILY SSF53850 29 249 1.98E-29 T 06-07-2017 CAK95_RS05905 b97f86e588346e822c82e66990770c89 319 Pfam PF09084 NMT1/THI5 like 47 249 8.9E-21 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS05905 b97f86e588346e822c82e66990770c89 319 Gene3D G3DSA:3.40.190.10 116 224 4.5E-13 T 06-07-2017 CAK95_RS19415 3664f7b875fa6d8fc60b804ea0a71372 357 Gene3D G3DSA:3.60.15.10 2 129 6.2E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS19415 3664f7b875fa6d8fc60b804ea0a71372 357 SUPERFAMILY SSF56281 1 155 3.92E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS19415 3664f7b875fa6d8fc60b804ea0a71372 357 SUPERFAMILY SSF56281 212 265 3.92E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS11615 29636b6d664b165027273e5ddbb905f0 349 Pfam PF01699 Sodium/calcium exchanger protein 202 318 3.4E-11 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK95_RS11615 29636b6d664b165027273e5ddbb905f0 349 Pfam PF01699 Sodium/calcium exchanger protein 13 139 5.4E-8 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK95_RS14585 a20e915afcf719ef9b3fb152e89dbf4a 176 Pfam PF02417 Chromate transporter 9 171 4.3E-36 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS16240 87ed772db69036dc9c4b3ef7943a1260 396 SUPERFAMILY SSF103473 5 390 1.22E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS16240 87ed772db69036dc9c4b3ef7943a1260 396 Pfam PF07690 Major Facilitator Superfamily 13 333 4.3E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS16240 87ed772db69036dc9c4b3ef7943a1260 396 Gene3D G3DSA:1.20.1250.20 210 385 3.6E-11 T 06-07-2017 CAK95_RS16240 87ed772db69036dc9c4b3ef7943a1260 396 Gene3D G3DSA:1.20.1250.20 6 183 1.5E-18 T 06-07-2017 CAK95_RS04585 b398d439380921e350c47eb55e5412d7 286 Pfam PF04444 Catechol dioxygenase N terminus 22 93 5.0E-32 T 06-07-2017 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CAK95_RS04585 b398d439380921e350c47eb55e5412d7 286 Gene3D G3DSA:2.60.130.10 2 285 1.7E-99 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS04585 b398d439380921e350c47eb55e5412d7 286 SUPERFAMILY SSF49482 1 285 1.3E-96 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAK95_RS04585 b398d439380921e350c47eb55e5412d7 286 Pfam PF00775 Dioxygenase 100 284 2.8E-55 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAK95_RS05435 a8bd4f79437fb5d1ff02c0770d65850b 477 SUPERFAMILY SSF111283 32 475 3.01E-125 T 06-07-2017 CAK95_RS05435 a8bd4f79437fb5d1ff02c0770d65850b 477 PIRSF PIRSF004919 18 476 9.3E-134 T 06-07-2017 IPR025502 TldD CAK95_RS05435 a8bd4f79437fb5d1ff02c0770d65850b 477 Pfam PF01523 Putative modulator of DNA gyrase 37 327 1.4E-60 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAK95_RS02655 529f1322041fe7e3b61e26af75396dae 215 Pfam PF01548 Transposase 5 149 4.5E-17 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CAK95_RS10370 90d1a30d049ec6100df5b541d0c7380d 247 Pfam PF08241 Methyltransferase domain 85 129 4.9E-8 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS10370 90d1a30d049ec6100df5b541d0c7380d 247 Gene3D G3DSA:3.40.50.150 89 181 3.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10370 90d1a30d049ec6100df5b541d0c7380d 247 SUPERFAMILY SSF53335 85 201 3.31E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS16655 5161e23059cb6010de5be79cad9c9172 377 TIGRFAM TIGR02714 amido_AtzD_TrzD: ring-opening amidohydrolases 4 366 1.2E-121 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAK95_RS16655 5161e23059cb6010de5be79cad9c9172 377 Pfam PF09663 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) 5 365 1.9E-135 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAK95_RS21860 5284f259d20d27e06ffcfd58afa221a2 350 Pfam PF04143 Sulphur transport 20 314 8.6E-22 T 06-07-2017 IPR007272 Sulphur transport domain CAK95_RS10155 8f4cbd1b40464c962c2085b62ef8dd31 379 Pfam PF00296 Luciferase-like monooxygenase 3 321 3.2E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS10155 8f4cbd1b40464c962c2085b62ef8dd31 379 SUPERFAMILY SSF51679 1 357 2.22E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS10155 8f4cbd1b40464c962c2085b62ef8dd31 379 Gene3D G3DSA:3.20.20.30 1 357 1.8E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS04060 c73333862f5bc5206ea405ad0e9cb278 137 SUPERFAMILY SSF53927 3 134 7.02E-26 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK95_RS04060 c73333862f5bc5206ea405ad0e9cb278 137 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 113 7.0E-10 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK95_RS04060 c73333862f5bc5206ea405ad0e9cb278 137 Gene3D G3DSA:3.40.140.10 3 135 8.0E-35 T 06-07-2017 CAK95_RS08290 a34f58cf3844e643303ed229cfebd0b3 485 Gene3D G3DSA:3.40.605.10 13 270 7.6E-91 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS08290 a34f58cf3844e643303ed229cfebd0b3 485 Gene3D G3DSA:3.40.309.10 271 456 5.5E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK95_RS08290 a34f58cf3844e643303ed229cfebd0b3 485 SUPERFAMILY SSF53720 11 484 5.89E-164 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK95_RS08290 a34f58cf3844e643303ed229cfebd0b3 485 Pfam PF00171 Aldehyde dehydrogenase family 21 481 2.4E-164 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK95_RS08290 a34f58cf3844e643303ed229cfebd0b3 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK95_RS20395 512ca3935cc37c0e66d0a2f947d49404 309 Gene3D G3DSA:3.40.50.300 30 230 9.8E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20395 512ca3935cc37c0e66d0a2f947d49404 309 SUPERFAMILY SSF52540 40 288 3.02E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS20395 512ca3935cc37c0e66d0a2f947d49404 309 Pfam PF07728 AAA domain (dynein-related subfamily) 45 199 2.9E-10 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAK95_RS26625 9a5768d1e41b03c6a98cac25e19b0876 265 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 67 202 3.5E-23 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS26625 9a5768d1e41b03c6a98cac25e19b0876 265 Gene3D G3DSA:3.40.50.150 46 207 1.6E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26625 9a5768d1e41b03c6a98cac25e19b0876 265 Pfam PF05050 Methyltransferase FkbM domain 67 203 3.1E-14 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK95_RS26625 9a5768d1e41b03c6a98cac25e19b0876 265 SUPERFAMILY SSF53335 25 226 6.22E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 1.3E-16 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 Pfam PF01192 RNA polymerase Rpb6 8 58 3.5E-12 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 SMART SM01409 8 60 2.1E-12 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 15.539 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 SUPERFAMILY SSF63562 1 81 1.44E-20 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK95_RS22325 9c515664daf1ebd898bfc7e03a4fe7c5 128 Gene3D G3DSA:3.90.940.10 1 65 3.5E-10 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK95_RS20270 87731f277010473c40e0e3e1801f0f18 179 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 134 1.1E-19 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS20270 87731f277010473c40e0e3e1801f0f18 179 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 114 133 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CAK95_RS20270 87731f277010473c40e0e3e1801f0f18 179 SUPERFAMILY SSF54593 3 136 2.55E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20270 87731f277010473c40e0e3e1801f0f18 179 Gene3D G3DSA:3.10.180.10 1 172 1.1E-44 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS08865 4b1b2b33f57c1d51534ce620d3d3e295 310 Pfam PF02371 Transposase IS116/IS110/IS902 family 190 274 3.5E-21 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CAK95_RS08865 4b1b2b33f57c1d51534ce620d3d3e295 310 Pfam PF01548 Transposase 8 147 2.7E-16 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CAK95_RS25635 689932d005b99ca09ffa1bccc0f2dd1d 104 Pfam PF12071 Protein of unknown function (DUF3551) 26 91 5.6E-12 T 06-07-2017 IPR021937 Protein of unknown function DUF3551 CAK95_RS11255 628d6da71ad35c000fc7b20d0292465a 216 Pfam PF03729 Short repeat of unknown function (DUF308) 39 109 1.6E-13 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK95_RS11255 628d6da71ad35c000fc7b20d0292465a 216 Pfam PF03729 Short repeat of unknown function (DUF308) 98 167 3.2E-9 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK95_RS13365 2e4a166e460e6d2546131306626f2ba5 274 Pfam PF01734 Patatin-like phospholipase 6 178 3.9E-17 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS13365 2e4a166e460e6d2546131306626f2ba5 274 SUPERFAMILY SSF52151 2 192 9.68E-42 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS13365 2e4a166e460e6d2546131306626f2ba5 274 Gene3D G3DSA:3.40.1090.10 6 173 3.0E-5 T 06-07-2017 CAK95_RS19790 caa7e20daa914bd59b47c718903475d7 229 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 108 226 1.8E-40 T 06-07-2017 IPR011969 Clan AA aspartic peptidase, C-terminal CAK95_RS19790 caa7e20daa914bd59b47c718903475d7 229 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 131 142 - T 06-07-2017 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 CAK95_RS19790 caa7e20daa914bd59b47c718903475d7 229 Pfam PF13975 gag-polyprotein putative aspartyl protease 122 212 3.9E-22 T 06-07-2017 CAK95_RS19790 caa7e20daa914bd59b47c718903475d7 229 SUPERFAMILY SSF50630 116 214 3.86E-13 T 06-07-2017 IPR021109 Aspartic peptidase domain CAK95_RS26190 777ef10f366702c01d78f994df3979c1 331 SUPERFAMILY SSF51430 3 309 3.67E-91 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS26190 777ef10f366702c01d78f994df3979c1 331 Pfam PF00248 Aldo/keto reductase family 16 308 3.0E-62 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS26190 777ef10f366702c01d78f994df3979c1 331 Gene3D G3DSA:3.20.20.100 1 321 1.0E-97 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 Pfam PF13437 HlyD family secretion protein 228 344 2.4E-16 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 SUPERFAMILY SSF111369 145 168 8.63E-16 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 SUPERFAMILY SSF111369 66 116 8.63E-16 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 SUPERFAMILY SSF111369 212 299 8.63E-16 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 Gene3D G3DSA:2.40.50.100 68 101 1.8E-17 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 Gene3D G3DSA:2.40.50.100 225 259 1.8E-17 T 06-07-2017 CAK95_RS10235 96fa2c2dda793fe09861339a52a7f692 376 Pfam PF13533 Biotin-lipoyl like 69 116 1.3E-15 T 06-07-2017 CAK95_RS24685 58f3812467e35e66d98d63902aa70a00 293 Gene3D G3DSA:3.40.50.620 58 254 2.1E-39 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS24685 58f3812467e35e66d98d63902aa70a00 293 SUPERFAMILY SSF52402 63 246 7.2E-36 T 06-07-2017 CAK95_RS24685 58f3812467e35e66d98d63902aa70a00 293 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 90 257 7.2E-30 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK95_RS03625 453c9f99cc8a53a3b702945ddbe59b4a 144 SUPERFAMILY SSF109709 55 114 2.88E-8 T 06-07-2017 CAK95_RS26100 47dd6869e151e067899475f5e501255d 263 SUPERFAMILY SSF52096 1 262 8.3E-88 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS26100 47dd6869e151e067899475f5e501255d 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 261 2.1E-63 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK95_RS26100 47dd6869e151e067899475f5e501255d 263 Gene3D G3DSA:3.90.226.10 2 260 1.8E-88 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK95_RS08305 b9c89859fb5184b24007a6bf1d4b2be7 445 PIRSF PIRSF004810 2 445 9.4E-119 T 06-07-2017 IPR014047 Chromate transporter, long chain CAK95_RS08305 b9c89859fb5184b24007a6bf1d4b2be7 445 Pfam PF02417 Chromate transporter 22 182 3.1E-34 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS08305 b9c89859fb5184b24007a6bf1d4b2be7 445 Pfam PF02417 Chromate transporter 246 438 2.3E-30 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAK95_RS08305 b9c89859fb5184b24007a6bf1d4b2be7 445 TIGRFAM TIGR00937 2A51: chromate efflux transporter 25 383 2.2E-61 T 06-07-2017 IPR014047 Chromate transporter, long chain CAK95_RS19380 15ce873698b2f125cfaf659bb35105f1 325 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 164 245 1.1E-4 T 06-07-2017 IPR024534 Domain of unknown function DUF2220 CAK95_RS22295 d3c7da1b5a0c7d49edb219673569356b 283 SUPERFAMILY SSF51556 17 283 5.3E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS22295 d3c7da1b5a0c7d49edb219673569356b 283 Gene3D G3DSA:3.20.20.140 9 283 1.5E-88 T 06-07-2017 CAK95_RS22295 d3c7da1b5a0c7d49edb219673569356b 283 Pfam PF04909 Amidohydrolase 23 283 2.2E-45 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS05355 f069d63ba976ac1205e2a36c6ee97583 229 Gene3D G3DSA:3.40.50.850 26 223 3.1E-55 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS05355 f069d63ba976ac1205e2a36c6ee97583 229 SUPERFAMILY SSF52499 22 222 2.49E-50 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS05355 f069d63ba976ac1205e2a36c6ee97583 229 Pfam PF00857 Isochorismatase family 32 218 1.7E-42 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS16880 b6c0b1cfc85e749300cdbeb6d48fbb30 259 SUPERFAMILY SSF161098 18 249 1.15E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16880 b6c0b1cfc85e749300cdbeb6d48fbb30 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 54 248 2.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16880 b6c0b1cfc85e749300cdbeb6d48fbb30 259 Gene3D G3DSA:1.10.3720.10 14 246 2.1E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04645 fee3f6061abd98b86b978b1454dd4a06 152 SUPERFAMILY SSF54427 29 141 1.86E-24 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS04645 fee3f6061abd98b86b978b1454dd4a06 152 Pfam PF12680 SnoaL-like domain 37 134 1.4E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS04645 fee3f6061abd98b86b978b1454dd4a06 152 Gene3D G3DSA:3.10.450.50 22 137 1.8E-10 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS21080 d1c086d5a3b31989ff8f989e84bcedc3 222 Pfam PF04191 Phospholipid methyltransferase 108 198 6.5E-12 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS12590 9db0eb785036197ee2bac0f3fdafd119 165 Gene3D G3DSA:2.60.120.10 21 139 1.5E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS12590 9db0eb785036197ee2bac0f3fdafd119 165 SMART SM00835 35 146 0.0085 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK95_RS12590 9db0eb785036197ee2bac0f3fdafd119 165 SUPERFAMILY SSF51182 10 151 8.25E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS12590 9db0eb785036197ee2bac0f3fdafd119 165 Pfam PF07883 Cupin domain 57 124 4.0E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS28505 a992a35e52d290acbc0bff16e69876b0 377 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 28 346 1.3E-135 T 06-07-2017 IPR017778 ABC transporter, urea, permease protein, UrtC CAK95_RS28505 a992a35e52d290acbc0bff16e69876b0 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 336 5.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS19815 a7b502a45ccbcd10417ba59b1fae5003 111 Gene3D G3DSA:1.20.1250.20 5 107 8.2E-5 T 06-07-2017 CAK95_RS19815 a7b502a45ccbcd10417ba59b1fae5003 111 SUPERFAMILY SSF103473 3 103 2.49E-7 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 Pfam PF13437 HlyD family secretion protein 198 305 1.2E-5 T 06-07-2017 CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 Gene3D G3DSA:2.40.50.100 196 223 3.7E-19 T 06-07-2017 CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 Gene3D G3DSA:2.40.50.100 88 121 3.7E-19 T 06-07-2017 CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 Pfam PF13533 Biotin-lipoyl like 89 133 1.2E-13 T 06-07-2017 CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 SUPERFAMILY SSF111369 79 313 6.15E-53 T 06-07-2017 CAK95_RS19570 ae43c29a256f50f38d609b71c8fc893c 402 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 63 390 3.2E-74 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAK95_RS17640 29472e9f81d787f95ef792c0a57752be 320 SUPERFAMILY SSF51735 11 316 8.85E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17640 29472e9f81d787f95ef792c0a57752be 320 Gene3D G3DSA:3.40.50.720 9 251 4.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17640 29472e9f81d787f95ef792c0a57752be 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 237 4.1E-24 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS18175 34e51642ea4d8774822bfa4a69ee7f24 136 Pfam PF10768 Class II flagellar assembly regulator 1 133 1.5E-35 T 06-07-2017 IPR019704 Flagellar assembly regulator FliX, class II CAK95_RS17930 76a8efa8e7ae5fa9945487671dcd7bdb 379 SUPERFAMILY SSF52091 13 99 1.59E-8 T 06-07-2017 IPR002645 STAS domain CAK95_RS17930 76a8efa8e7ae5fa9945487671dcd7bdb 379 Gene3D G3DSA:3.30.750.24 17 96 1.5E-6 T 06-07-2017 IPR002645 STAS domain CAK95_RS17930 76a8efa8e7ae5fa9945487671dcd7bdb 379 Pfam PF02405 Permease MlaE 162 372 1.5E-69 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK95_RS17930 76a8efa8e7ae5fa9945487671dcd7bdb 379 Pfam PF13466 STAS domain 18 96 3.9E-10 T 06-07-2017 IPR002645 STAS domain CAK95_RS17930 76a8efa8e7ae5fa9945487671dcd7bdb 379 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 139 374 6.2E-68 T 06-07-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CAK95_RS06800 b85a608114c26ffd65f041829d4c9e45 241 Pfam PF11064 Protein of unknown function (DUF2865) 74 175 2.2E-28 T 06-07-2017 IPR021293 Protein of unknown function DUF2865 CAK95_RS13405 c5c48ac915a94eed504d46b4ded3ce99 428 SUPERFAMILY SSF53756 53 415 8.37E-12 T 06-07-2017 CAK95_RS13405 c5c48ac915a94eed504d46b4ded3ce99 428 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 207 8.4E-57 T 06-07-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 CAK95_RS01080 4f045cd1e6c432e68c6b01d14fef4f00 454 Gene3D G3DSA:3.30.1330.120 255 358 9.8E-14 T 06-07-2017 CAK95_RS01080 4f045cd1e6c432e68c6b01d14fef4f00 454 Pfam PF03972 MmgE/PrpD family 7 412 5.8E-72 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS01080 4f045cd1e6c432e68c6b01d14fef4f00 454 SUPERFAMILY SSF103378 6 413 3.92E-70 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK95_RS02960 ce8fb5435cc42f9195f706c9b2bf127e 420 Gene3D G3DSA:3.40.50.150 37 106 2.0E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02960 ce8fb5435cc42f9195f706c9b2bf127e 420 SUPERFAMILY SSF53335 32 102 7.87E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02960 ce8fb5435cc42f9195f706c9b2bf127e 420 Pfam PF01555 DNA methylase 38 90 3.7E-11 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 Pfam PF07687 Peptidase dimerisation domain 204 363 7.9E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 Gene3D G3DSA:3.40.630.10 9 200 2.7E-60 T 06-07-2017 CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 Gene3D G3DSA:3.40.630.10 376 463 2.7E-60 T 06-07-2017 CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 Gene3D G3DSA:3.30.70.360 206 372 3.0E-57 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 Pfam PF01546 Peptidase family M20/M25/M40 87 460 1.5E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 SUPERFAMILY SSF53187 9 206 1.89E-60 T 06-07-2017 CAK95_RS18770 54c7794b3569d34eba49ada287c73a2f 464 SUPERFAMILY SSF53187 377 463 1.89E-60 T 06-07-2017 CAK95_RS25665 88e29e9becbcada2f041a02cbf15bbd6 54 Pfam PF06568 Domain of unknown function (DUF1127) 18 47 4.7E-12 T 06-07-2017 IPR009506 Protein of unknown function DUF1127 CAK95_RS05295 bcb8ac44c83d566d5e96bf0ca996d300 301 Gene3D G3DSA:3.60.15.10 6 289 4.2E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS05295 bcb8ac44c83d566d5e96bf0ca996d300 301 Pfam PF12706 Beta-lactamase superfamily domain 34 245 7.8E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS05295 bcb8ac44c83d566d5e96bf0ca996d300 301 SMART SM00849 22 222 1.6E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS05295 bcb8ac44c83d566d5e96bf0ca996d300 301 SUPERFAMILY SSF56281 6 285 2.49E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS12710 6cc9c56bae5bf17e72e5d93172da6c82 503 PIRSF PIRSF016636 12 503 4.1E-140 T 06-07-2017 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CAK95_RS12710 6cc9c56bae5bf17e72e5d93172da6c82 503 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 157 367 1.8E-31 T 06-07-2017 IPR004299 Membrane bound O-acyl transferase, MBOAT CAK95_RS12710 6cc9c56bae5bf17e72e5d93172da6c82 503 PIRSF PIRSF500217 12 503 3.7E-141 T 06-07-2017 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CAK95_RS01825 4d960640c355e17cf3861eb5139bba9e 304 Gene3D G3DSA:1.20.1510.10 27 214 1.3E-51 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK95_RS01825 4d960640c355e17cf3861eb5139bba9e 304 SUPERFAMILY SSF161111 24 215 4.84E-51 T 06-07-2017 CAK95_RS01825 4d960640c355e17cf3861eb5139bba9e 304 SUPERFAMILY SSF160240 224 294 6.41E-8 T 06-07-2017 CAK95_RS01825 4d960640c355e17cf3861eb5139bba9e 304 Pfam PF01545 Cation efflux family 28 213 2.3E-39 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS01825 4d960640c355e17cf3861eb5139bba9e 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 295 1.9E-76 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK95_RS25705 4552601fff40ea32f31593629a758772 282 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 281 4.3E-125 T 06-07-2017 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD-Fe KEGG: 00350+1.13.11.15 CAK95_RS25705 4552601fff40ea32f31593629a758772 282 Gene3D G3DSA:3.40.830.10 5 275 3.2E-28 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS25705 4552601fff40ea32f31593629a758772 282 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 279 3.4E-54 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS25705 4552601fff40ea32f31593629a758772 282 SUPERFAMILY SSF53213 13 279 2.62E-44 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK95_RS27960 dfb4750235abfd4a025dfbe2e4e3c138 108 Gene3D G3DSA:1.10.238.120 6 107 6.1E-32 T 06-07-2017 IPR023154 Jann4075-like domain CAK95_RS27960 dfb4750235abfd4a025dfbe2e4e3c138 108 Pfam PF11015 Protein of unknown function (DUF2853) 7 105 1.0E-31 T 06-07-2017 IPR021274 Protein of unknown function DUF2853 CAK95_RS27960 dfb4750235abfd4a025dfbe2e4e3c138 108 SUPERFAMILY SSF158587 5 107 4.32E-30 T 06-07-2017 IPR023154 Jann4075-like domain CAK95_RS03105 9a8b3800ef9254927b8d8c6dbb3adda8 668 Pfam PF05876 Phage terminase large subunit (GpA) 53 613 1.5E-202 T 06-07-2017 IPR008866 Bacteriophage lambda, GpA CAK95_RS01330 4ca7a9a9609f6d75fff5482c7d167016 164 Pfam PF07681 DoxX 23 108 9.9E-20 T 06-07-2017 IPR032808 DoxX family CAK95_RS19245 046ab3071fff05d763243bf265cf9d0d 520 SUPERFAMILY SSF56672 31 241 9.93E-34 T 06-07-2017 CAK95_RS19245 046ab3071fff05d763243bf265cf9d0d 520 Pfam PF00817 impB/mucB/samB family 34 161 4.2E-6 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK95_RS13845 1f107ff3499d5b56cd6e6ddbbbe9a3fd 150 Gene3D G3DSA:1.10.1510.10 2 92 5.1E-31 T 06-07-2017 CAK95_RS13845 1f107ff3499d5b56cd6e6ddbbbe9a3fd 150 SUPERFAMILY SSF89095 1 148 2.51E-41 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAK95_RS13845 1f107ff3499d5b56cd6e6ddbbbe9a3fd 150 Pfam PF09424 Yqey-like protein 4 148 8.5E-51 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial CAK95_RS13845 1f107ff3499d5b56cd6e6ddbbbe9a3fd 150 Gene3D G3DSA:1.10.10.410 93 148 1.7E-20 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAK95_RS07530 2c72923f580ba96e51d29888c22948f0 856 Pfam PF02687 FtsX-like permease family 276 389 1.4E-15 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK95_RS07530 2c72923f580ba96e51d29888c22948f0 856 Pfam PF02687 FtsX-like permease family 736 845 3.2E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK95_RS18755 9443d0ab1a9155e6420464b423d78997 135 Pfam PF14229 Domain of unknown function (DUF4332) 15 129 4.7E-33 T 06-07-2017 IPR025567 Domain of unknown function DUF4332 KEGG: 00970+6.1.1.6 CAK95_RS18755 9443d0ab1a9155e6420464b423d78997 135 Gene3D G3DSA:1.10.150.20 3 53 2.0E-4 T 06-07-2017 CAK95_RS18755 9443d0ab1a9155e6420464b423d78997 135 Gene3D G3DSA:1.10.150.20 61 99 1.7E-4 T 06-07-2017 CAK95_RS26580 20fb62dc0e16439f3e6f250ee1df857f 321 SUPERFAMILY SSF51695 32 311 1.31E-43 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS26580 20fb62dc0e16439f3e6f250ee1df857f 321 Gene3D G3DSA:3.20.20.190 12 316 4.4E-44 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK95_RS26580 20fb62dc0e16439f3e6f250ee1df857f 321 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 62 173 8.5E-20 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAK95_RS28040 c74f88c8bc8e70b7cf9055ce3e04d598 383 Pfam PF05987 Bacterial protein of unknown function (DUF898) 20 231 3.7E-56 T 06-07-2017 IPR010295 Protein of unknown function DUF898 CAK95_RS28040 c74f88c8bc8e70b7cf9055ce3e04d598 383 Pfam PF05987 Bacterial protein of unknown function (DUF898) 220 376 2.9E-7 T 06-07-2017 IPR010295 Protein of unknown function DUF898 CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 3.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 Gene3D G3DSA:3.40.50.720 3 250 7.2E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 SUPERFAMILY SSF51735 6 250 6.24E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS07400 f31df727581f76d4b250783cd66f685a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 249 1.9E-50 T 06-07-2017 CAK95_RS21780 7baefb7173d7acf8101968a585f95c5e 230 SUPERFAMILY SSF89562 9 187 2.75E-36 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS21780 7baefb7173d7acf8101968a585f95c5e 230 Gene3D G3DSA:3.50.30.40 9 184 4.7E-37 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS21780 7baefb7173d7acf8101968a585f95c5e 230 Pfam PF03737 Demethylmenaquinone methyltransferase 22 176 3.3E-27 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK95_RS02920 2dbf648bd126fd66851184987c25b72e 230 SUPERFAMILY SSF161098 14 221 1.57E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS02920 2dbf648bd126fd66851184987c25b72e 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 213 5.7E-9 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS02920 2dbf648bd126fd66851184987c25b72e 230 Gene3D G3DSA:1.10.3720.10 15 227 8.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS08285 883017f6e2a3e6db496ffd445c89612e 203 Pfam PF01810 LysE type translocator 15 199 3.7E-26 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS28775 d6bd18c9455be984496e7821ce2da75a 302 Gene3D G3DSA:3.20.20.370 3 299 2.0E-90 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS28775 d6bd18c9455be984496e7821ce2da75a 302 Pfam PF01522 Polysaccharide deacetylase 66 160 4.7E-14 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS28775 d6bd18c9455be984496e7821ce2da75a 302 SUPERFAMILY SSF88713 3 298 4.7E-76 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS22935 fed8cbfa8ed93bec56652165e2e2f1ab 233 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK95_RS22935 fed8cbfa8ed93bec56652165e2e2f1ab 233 SUPERFAMILY SSF52540 13 232 8.62E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS22935 fed8cbfa8ed93bec56652165e2e2f1ab 233 Pfam PF00005 ABC transporter 33 179 1.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS22935 fed8cbfa8ed93bec56652165e2e2f1ab 233 SMART SM00382 40 232 1.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS22935 fed8cbfa8ed93bec56652165e2e2f1ab 233 Gene3D G3DSA:3.40.50.300 11 231 7.4E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS06635 5c2374ff2ecc35fc9b04dcf0a45b2534 52 Pfam PF04964 Flp/Fap pilin component 8 48 1.7E-13 T 06-07-2017 IPR007047 Flp/Fap pilin component CAK95_RS27645 4bd0bae9cc125c11ec398d2883e8a09a 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 273 5.3E-42 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS19525 269bc9f0a5a4118308344de4d9a70659 111 Pfam PF05284 Protein of unknown function (DUF736) 3 104 1.7E-37 T 06-07-2017 IPR007948 Protein of unknown function DUF736 CAK95_RS28095 eb4ddcc01a9ea42d358a449967327b6c 364 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 27 324 8.2E-41 T 06-07-2017 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CAK95_RS28095 eb4ddcc01a9ea42d358a449967327b6c 364 Gene3D G3DSA:3.60.60.10 27 341 2.6E-96 T 06-07-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 CAK95_RS28095 eb4ddcc01a9ea42d358a449967327b6c 364 SUPERFAMILY SSF56235 27 340 2.62E-88 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK95_RS25510 3bd29e52c4be899ae0f678833676e87a 182 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 2.2E-23 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 SMART SM00347 74 177 2.5E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 133 2.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 2.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 153 2.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 PRINTS PR00598 Bacterial regulatory protein MarR family signature 167 187 2.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 SUPERFAMILY SSF46785 40 191 1.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 Pfam PF12802 MarR family 85 141 2.4E-7 T 06-07-2017 CAK95_RS28745 0e9ade21082cb49ee79d20ebba46a808 198 Gene3D G3DSA:1.10.10.10 42 191 1.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS13480 25be2077efc45f31ca4b580c12dcfb40 97 Pfam PF14110 Domain of unknown function (DUF4282) 8 91 1.4E-19 T 06-07-2017 IPR025557 Protein of unknown function DUF4282 CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 183 288 1.7E-21 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 5 135 1.9E-29 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 Gene3D G3DSA:2.60.120.330 3 322 4.5E-93 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 SUPERFAMILY SSF51197 2 321 7.55E-88 T 06-07-2017 CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 PRINTS PR00682 Isopenicillin N synthase signature 157 173 7.9E-9 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 PRINTS PR00682 Isopenicillin N synthase signature 243 269 7.9E-9 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS00400 a1aca95c1710b077b6fefdb4e1bc12bc 326 PRINTS PR00682 Isopenicillin N synthase signature 28 45 7.9E-9 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS06915 499bf8e35902dc6d27c9472ed791e4b3 166 SUPERFAMILY SSF55729 1 165 3.54E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS06915 499bf8e35902dc6d27c9472ed791e4b3 166 Pfam PF13420 Acetyltransferase (GNAT) domain 4 161 4.4E-15 T 06-07-2017 CAK95_RS06915 499bf8e35902dc6d27c9472ed791e4b3 166 Gene3D G3DSA:3.40.630.30 2 166 2.4E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS23450 edada2c511cbd4c6e11455a43ec7a029 286 SUPERFAMILY SSF46626 171 285 3.78E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23450 edada2c511cbd4c6e11455a43ec7a029 286 SUPERFAMILY SSF46626 48 163 2.64E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23450 edada2c511cbd4c6e11455a43ec7a029 286 Gene3D G3DSA:1.10.760.10 92 285 9.2E-51 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK95_RS23450 edada2c511cbd4c6e11455a43ec7a029 286 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 59 286 4.6E-68 T 06-07-2017 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 CAK95_RS10910 6a09deb3cd4d5e77662a6852983aefc6 134 Pfam PF09538 Protein of unknown function (FYDLN_acid) 2 114 3.3E-29 T 06-07-2017 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid CAK95_RS10910 6a09deb3cd4d5e77662a6852983aefc6 134 TIGRFAM TIGR02300 FYDLN_acid: TIGR02300 family protein 1 125 2.4E-39 T 06-07-2017 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid CAK95_RS07975 e65262c161ae41f6c5a9522848b35132 97 Pfam PF12071 Protein of unknown function (DUF3551) 22 94 9.2E-15 T 06-07-2017 IPR021937 Protein of unknown function DUF3551 CAK95_RS11865 b79fae36ea4a4b102749672e7e895fff 147 Pfam PF13801 Heavy-metal resistance 17 139 3.2E-19 T 06-07-2017 IPR025961 Heavy-metal resistance protein CAK95_RS14720 2a0c65ec486b3606a237c4bc55276ecb 351 SUPERFAMILY SSF53850 114 303 2.42E-5 T 06-07-2017 CAK95_RS14720 2a0c65ec486b3606a237c4bc55276ecb 351 PIRSF PIRSF017082 35 351 2.1E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14720 2a0c65ec486b3606a237c4bc55276ecb 351 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 81 345 3.0E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01340 751ac5975b984eef5856356c2508ec98 232 SUPERFAMILY SSF52833 62 231 1.67E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01340 751ac5975b984eef5856356c2508ec98 232 Gene3D G3DSA:3.40.30.10 64 231 1.1E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01340 751ac5975b984eef5856356c2508ec98 232 Pfam PF08534 Redoxin 65 226 4.0E-20 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK95_RS05610 13bca9d00bceb532f2044c00be21d930 712 SUPERFAMILY SSF52540 135 313 1.55E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26795 691e9ae047e5081aa285470e4cff3bbc 495 Gene3D G3DSA:3.40.720.10 265 442 7.6E-12 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK95_RS26795 691e9ae047e5081aa285470e4cff3bbc 495 Pfam PF00884 Sulfatase 225 443 2.6E-21 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK95_RS26795 691e9ae047e5081aa285470e4cff3bbc 495 SUPERFAMILY SSF53649 223 453 2.83E-21 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK95_RS07155 b8c24db301a58e8cc35f00ca7562db46 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 315 1.3E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07155 b8c24db301a58e8cc35f00ca7562db46 322 PIRSF PIRSF017082 1 320 1.9E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS07155 b8c24db301a58e8cc35f00ca7562db46 322 SUPERFAMILY SSF53850 100 275 4.89E-12 T 06-07-2017 CAK95_RS15280 1a4683955a3c4bb4354714669c360023 415 SUPERFAMILY SSF51726 51 413 1.31E-69 T 06-07-2017 CAK95_RS15280 1a4683955a3c4bb4354714669c360023 415 Gene3D G3DSA:3.20.20.210 46 413 3.7E-97 T 06-07-2017 CAK95_RS15280 1a4683955a3c4bb4354714669c360023 415 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 53 409 1.5E-13 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS14735 792e0aa0dd9de19b7bd6855be2cf5b6d 352 Gene3D G3DSA:3.60.15.10 20 310 5.0E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS14735 792e0aa0dd9de19b7bd6855be2cf5b6d 352 Pfam PF12706 Beta-lactamase superfamily domain 50 268 7.5E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS14735 792e0aa0dd9de19b7bd6855be2cf5b6d 352 SUPERFAMILY SSF56281 20 301 4.19E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS00990 914c5ed7ed3fe7ee0373fcbaaaaa85a0 418 Gene3D G3DSA:3.40.190.10 144 342 1.4E-35 T 06-07-2017 CAK95_RS00990 914c5ed7ed3fe7ee0373fcbaaaaa85a0 418 SUPERFAMILY SSF53850 24 414 4.04E-63 T 06-07-2017 CAK95_RS00990 914c5ed7ed3fe7ee0373fcbaaaaa85a0 418 Pfam PF13416 Bacterial extracellular solute-binding protein 44 360 3.8E-34 T 06-07-2017 CAK95_RS24870 60162392c1357b04e2ce40d757fd14ff 304 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 298 2.9E-64 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24870 60162392c1357b04e2ce40d757fd14ff 304 Gene3D G3DSA:3.90.850.10 77 300 7.3E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24870 60162392c1357b04e2ce40d757fd14ff 304 SUPERFAMILY SSF56529 77 299 7.2E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS23860 87d8ff3dab44364e94445d9a022842e5 127 SUPERFAMILY SSF64076 8 126 2.09E-36 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAK95_RS23860 87d8ff3dab44364e94445d9a022842e5 127 Gene3D G3DSA:3.40.1230.10 10 126 7.1E-36 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAK95_RS23860 87d8ff3dab44364e94445d9a022842e5 127 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 16 124 3.1E-28 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAK95_RS24155 cc60df0e7eacdb4f4df0b308cd030565 296 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 283 7.7E-49 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24155 cc60df0e7eacdb4f4df0b308cd030565 296 SUPERFAMILY SSF56529 69 284 2.75E-57 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS24155 cc60df0e7eacdb4f4df0b308cd030565 296 Gene3D G3DSA:3.90.850.10 64 284 1.6E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS00445 921ba0b066b80067f45b627d21975897 71 SUPERFAMILY SSF57884 8 58 3.79E-5 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAK95_RS03355 254f039b4182b3fd83f8b9ba7e99332d 78 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 1 77 1.0E-22 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAK95_RS16785 2d91c74a14e598da1703a3ad75f3712f 108 Pfam PF09361 Phasin protein 41 93 1.3E-5 T 06-07-2017 IPR018968 Phasin CAK95_RS23420 6cff257b248e52c7b314956ecbbd3759 378 Pfam PF04143 Sulphur transport 28 339 2.6E-62 T 06-07-2017 IPR007272 Sulphur transport domain CAK95_RS12310 352ad764f1bd3187d370e19029df66dc 81 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 13 72 7.6E-27 T 06-07-2017 IPR021074 Formate dehydrogenase, delta subunit CAK95_RS08485 d8f7289c247d46afdec861b8be108e1c 590 Pfam PF07940 Heparinase II/III-like protein 310 559 2.9E-64 T 06-07-2017 IPR012480 Heparinase II/III-like GO:0016829 CAK95_RS03185 330bd2312cd391c500440278b66c4be8 1039 Pfam PF06791 Prophage tail length tape measure protein 164 375 1.7E-53 T 06-07-2017 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 SUPERFAMILY SSF53850 91 300 2.6E-33 T 06-07-2017 CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 Gene3D G3DSA:1.10.10.10 7 88 5.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 Pfam PF03466 LysR substrate binding domain 89 293 6.1E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 Gene3D G3DSA:3.40.190.10 90 180 4.1E-20 T 06-07-2017 CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 SUPERFAMILY SSF46785 5 113 4.24E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 1.7E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK95_RS16660 3ab39b77d0ffd07389d89a7fdb7b17c2 316 Gene3D G3DSA:3.40.190.10 181 266 4.3E-15 T 06-07-2017 CAK95_RS14205 088a12acfe2e388411b6fe595ca19f94 163 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 14 152 1.1E-14 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS06520 70237ccd13524722631e186fdf69b136 275 Pfam PF11306 Protein of unknown function (DUF3108) 22 262 2.6E-24 T 06-07-2017 IPR021457 Protein of unknown function DUF3108 CAK95_RS24570 06fe298511b71e4521931533a53643c1 73 Gene3D G3DSA:1.10.260.40 13 71 1.1E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS15050 7754ff8182d418cc787440f87c2f5c74 171 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 6 119 9.9E-29 T 06-07-2017 IPR012659 Conserved hypothetical protein CHP02444 CAK95_RS15050 7754ff8182d418cc787440f87c2f5c74 171 Pfam PF09523 Protein of unknown function (DUF2390) 6 118 1.6E-29 T 06-07-2017 IPR012659 Conserved hypothetical protein CHP02444 CAK95_RS16455 4c3a39321d7d455af4bb68aecd83c0e6 202 Pfam PF13460 NAD(P)H-binding 7 189 4.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16455 4c3a39321d7d455af4bb68aecd83c0e6 202 SUPERFAMILY SSF51735 1 200 2.86E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16455 4c3a39321d7d455af4bb68aecd83c0e6 202 Gene3D G3DSA:3.40.50.720 1 202 5.9E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26260 ccf92e1c458a8a8186dcafb17cb3a77e 157 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 116 157 4.0E-7 T 06-07-2017 CAK95_RS26260 ccf92e1c458a8a8186dcafb17cb3a77e 157 Pfam PF04191 Phospholipid methyltransferase 45 146 4.0E-15 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 Gene3D G3DSA:3.40.630.30 13 184 8.0E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 PRINTS PR01549 Autoinducer synthesis protein signature 71 89 6.1E-5 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 PRINTS PR01549 Autoinducer synthesis protein signature 47 69 6.1E-5 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 PRINTS PR01549 Autoinducer synthesis protein signature 104 116 6.1E-5 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 Pfam PF00765 Autoinducer synthase 30 158 5.0E-9 T 06-07-2017 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CAK95_RS03675 aafe0484f31ff2d93f677e1201f90d25 214 SUPERFAMILY SSF55729 18 180 7.95E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS09390 d1e67cfbb2d0ba71868b95d74b13a301 359 Pfam PF03601 Conserved hypothetical protein 698 26 340 3.8E-64 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 Pfam PF00033 Cytochrome b/b6/petB 32 218 4.4E-75 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 Gene3D G3DSA:1.20.810.10 14 395 6.7E-175 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 SUPERFAMILY SSF81342 14 277 1.49E-107 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 PIRSF PIRSF038885 5 406 6.3E-197 T 06-07-2017 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 SUPERFAMILY SSF81648 278 398 5.23E-43 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAK95_RS00560 434e3230eb34ee9ab2251ffc9b56f73c 420 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 275 376 1.1E-40 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAK95_RS14200 c294157a83117f9a994837cb02be97d0 358 SUPERFAMILY SSF53850 156 323 2.06E-7 T 06-07-2017 CAK95_RS14200 c294157a83117f9a994837cb02be97d0 358 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 87 338 2.6E-45 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS14200 c294157a83117f9a994837cb02be97d0 358 PIRSF PIRSF017082 39 357 1.8E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS02460 d35f6ab39fcbcc20273dfe38dc105fca 677 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 112 553 1.8E-100 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CAK95_RS02460 d35f6ab39fcbcc20273dfe38dc105fca 677 Gene3D G3DSA:3.40.50.300 101 209 8.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02460 d35f6ab39fcbcc20273dfe38dc105fca 677 Gene3D G3DSA:3.40.50.300 348 549 8.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS02460 d35f6ab39fcbcc20273dfe38dc105fca 677 SUPERFAMILY SSF52540 107 551 1.38E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS16950 f8eb2d523770045e030e8498ef1bd640 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 334 2.6E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16950 f8eb2d523770045e030e8498ef1bd640 337 SUPERFAMILY SSF161098 91 159 3.27E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS16950 f8eb2d523770045e030e8498ef1bd640 337 SUPERFAMILY SSF161098 198 320 3.27E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS18140 cd25170ffc17648388ddb954c295a24b 144 PIRSF PIRSF009533 1 141 1.8E-41 T 06-07-2017 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 CAK95_RS18140 cd25170ffc17648388ddb954c295a24b 144 Pfam PF07378 Flagellar protein FlbT 3 124 1.9E-43 T 06-07-2017 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 CAK95_RS13645 4c7d6894d051ed7698a0ae619db7a1c0 93 Pfam PF13937 Domain of unknown function (DUF4212) 15 89 1.5E-26 T 06-07-2017 IPR019886 Sodium symporter small subunit, predicted CAK95_RS13645 4c7d6894d051ed7698a0ae619db7a1c0 93 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 16 91 4.3E-25 T 06-07-2017 IPR019886 Sodium symporter small subunit, predicted CAK95_RS06070 aa0444144efeb2e0f67daa05395c5f1d 180 SMART SM00260 30 167 5.0E-39 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS06070 aa0444144efeb2e0f67daa05395c5f1d 180 Gene3D G3DSA:2.40.50.180 72 117 4.7E-10 T 06-07-2017 CAK95_RS06070 aa0444144efeb2e0f67daa05395c5f1d 180 Pfam PF01584 CheW-like domain 34 168 3.0E-33 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS06070 aa0444144efeb2e0f67daa05395c5f1d 180 SUPERFAMILY SSF50341 34 168 6.67E-36 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAK95_RS18670 59e3fb02d41363e60153dc0d19097020 366 SUPERFAMILY SSF51395 3 351 1.66E-104 T 06-07-2017 CAK95_RS18670 59e3fb02d41363e60153dc0d19097020 366 Gene3D G3DSA:3.20.20.70 3 353 3.9E-114 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS18670 59e3fb02d41363e60153dc0d19097020 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 333 7.7E-57 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK95_RS11720 3c78fdd9eb4e299e901f270202c2e5d4 234 Gene3D G3DSA:3.30.70.1230 43 202 1.3E-6 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK95_RS11720 3c78fdd9eb4e299e901f270202c2e5d4 234 SUPERFAMILY SSF55073 38 202 1.43E-18 T 06-07-2017 IPR029787 Nucleotide cyclase CAK95_RS06675 6e0cac266157229bf2acedffc0b04f75 327 Pfam PF00482 Type II secretion system (T2SS), protein F 161 284 1.9E-20 T 06-07-2017 IPR018076 Type II secretion system F domain CAK95_RS14510 ddd175b7db43146b2a64aefb932a2c0e 144 Gene3D G3DSA:3.90.1590.10 3 142 1.4E-27 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS14510 ddd175b7db43146b2a64aefb932a2c0e 144 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 30 124 1.9E-18 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAK95_RS14510 ddd175b7db43146b2a64aefb932a2c0e 144 SUPERFAMILY SSF51316 8 143 4.18E-31 T 06-07-2017 IPR011057 Mss4-like CAK95_RS18460 a0797595ad19451d7ec6d70ce5542904 359 Pfam PF00296 Luciferase-like monooxygenase 1 319 2.3E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS18460 a0797595ad19451d7ec6d70ce5542904 359 SUPERFAMILY SSF51679 1 350 3.14E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS18460 a0797595ad19451d7ec6d70ce5542904 359 Gene3D G3DSA:3.20.20.30 1 356 3.6E-88 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS01920 8cfebcd7f75d61cf4e0891fe175956bc 654 Pfam PF13667 ThiC-associated domain 20 91 1.8E-23 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK95_RS01920 8cfebcd7f75d61cf4e0891fe175956bc 654 Pfam PF01964 Radical SAM ThiC family 131 578 8.0E-198 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK95_RS01920 8cfebcd7f75d61cf4e0891fe175956bc 654 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 130 582 7.6E-211 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK95_RS01920 8cfebcd7f75d61cf4e0891fe175956bc 654 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 130 584 55.962 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 06-07-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 91 1.2E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 Gene3D G3DSA:3.10.20.30 1 102 4.1E-40 T 06-07-2017 IPR012675 Beta-grasp domain CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 SUPERFAMILY SSF54292 3 104 4.11E-35 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 PRINTS PR00355 Adrenodoxin signature 82 90 1.2E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 PRINTS PR00355 Adrenodoxin signature 59 73 1.2E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS17980 d7425b318405e1dd8796ec344f4ec2a9 106 PRINTS PR00355 Adrenodoxin signature 40 50 1.2E-8 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK95_RS06900 bee1189a666f31aa888526e6af218993 326 Gene3D G3DSA:2.130.10.130 194 266 4.4E-5 T 06-07-2017 CAK95_RS06900 bee1189a666f31aa888526e6af218993 326 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 198 265 3.2E-8 T 06-07-2017 CAK95_RS06900 bee1189a666f31aa888526e6af218993 326 SUPERFAMILY SSF69318 190 267 1.22E-9 T 06-07-2017 CAK95_RS28000 11c2178ccc5fd56f672f1a584a96802e 110 Pfam PF07769 psiF repeat 38 60 5.5E-5 T 06-07-2017 IPR011690 Phosphate-starvation-induced PsiF repeat CAK95_RS22320 d2656118cc0c41bad5c9b0514f2dfa57 218 Gene3D G3DSA:3.40.50.1010 3 164 2.9E-48 T 06-07-2017 IPR029060 PIN domain-like CAK95_RS22320 d2656118cc0c41bad5c9b0514f2dfa57 218 Pfam PF01936 NYN domain 7 164 4.6E-39 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type CAK95_RS13950 bed77b9ec6f43f08d9e71570e47c8316 265 Gene3D G3DSA:3.40.50.150 7 233 2.1E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13950 bed77b9ec6f43f08d9e71570e47c8316 265 SUPERFAMILY SSF53335 4 237 4.26E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13950 bed77b9ec6f43f08d9e71570e47c8316 265 Pfam PF08241 Methyltransferase domain 53 148 2.1E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 SUPERFAMILY SSF48179 184 332 1.41E-71 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 SUPERFAMILY SSF51735 1 183 3.16E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 6.0E-74 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 5.0E-67 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 328 4.4E-132 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 Gene3D G3DSA:1.10.1040.10 29 326 4.9E-116 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK95_RS14715 d31ccaaaf2b467233c6dbf67ab31f6eb 339 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 329 45.382 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK95_RS04860 c2e3f2226572282f364945a518efbb8e 543 Pfam PF03929 PepSY-associated TM region 18 368 5.6E-44 T 06-07-2017 IPR005625 PepSY-associated TM protein CAK95_RS07730 12126c9175bc8c159f9003d22359779f 292 PIRSF PIRSF015582 1 292 4.3E-73 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK95_RS07730 12126c9175bc8c159f9003d22359779f 292 SUPERFAMILY SSF51621 3 236 2.31E-66 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS07730 12126c9175bc8c159f9003d22359779f 292 Gene3D G3DSA:3.20.20.60 3 237 1.6E-72 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK95_RS07730 12126c9175bc8c159f9003d22359779f 292 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 225 2.8E-44 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK95_RS07245 8902329a098175ace9a42a6fc2734140 328 Gene3D G3DSA:3.20.20.140 3 328 3.4E-90 T 06-07-2017 CAK95_RS07245 8902329a098175ace9a42a6fc2734140 328 SUPERFAMILY SSF51556 3 328 6.81E-81 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS07245 8902329a098175ace9a42a6fc2734140 328 Pfam PF04909 Amidohydrolase 4 328 7.0E-39 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS12265 8b96482110455cc66c26e00a81ee730b 412 SUPERFAMILY SSF89796 3 400 3.4E-116 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12265 8b96482110455cc66c26e00a81ee730b 412 Gene3D G3DSA:3.30.1540.10 231 311 4.1E-17 T 06-07-2017 CAK95_RS12265 8b96482110455cc66c26e00a81ee730b 412 Gene3D G3DSA:3.40.50.10540 5 224 1.4E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12265 8b96482110455cc66c26e00a81ee730b 412 Gene3D G3DSA:3.40.50.10540 312 400 1.4E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK95_RS12265 8b96482110455cc66c26e00a81ee730b 412 Pfam PF02515 CoA-transferase family III 8 378 3.0E-113 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK95_RS09660 fa32ce0a28f974aa96d09c1df6b37877 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 315 7.4E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS04810 c8576b1770c5fc17ea38b0c305f74674 377 SUPERFAMILY SSF51556 91 376 1.11E-73 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS04810 c8576b1770c5fc17ea38b0c305f74674 377 Pfam PF04909 Amidohydrolase 100 376 1.2E-47 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS04810 c8576b1770c5fc17ea38b0c305f74674 377 Gene3D G3DSA:3.20.20.140 66 376 1.3E-88 T 06-07-2017 CAK95_RS20450 291c918889f545c04ca62d356b178c61 409 Gene3D G3DSA:1.20.1250.20 54 195 9.9E-21 T 06-07-2017 CAK95_RS20450 291c918889f545c04ca62d356b178c61 409 Gene3D G3DSA:1.20.1250.20 216 391 1.5E-7 T 06-07-2017 CAK95_RS20450 291c918889f545c04ca62d356b178c61 409 Pfam PF07690 Major Facilitator Superfamily 41 242 1.7E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS20450 291c918889f545c04ca62d356b178c61 409 SUPERFAMILY SSF103473 11 392 2.35E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS14985 1b449b9491a6ab1865a8d645d46336a7 302 Gene3D G3DSA:3.20.20.70 4 293 2.5E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS14985 1b449b9491a6ab1865a8d645d46336a7 302 Pfam PF05853 beta-keto acid cleavage enzyme 5 292 1.8E-89 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 CAK95_RS28025 291ddcc6944c4b2fc0605c622e95ba9e 470 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 66 154 1.3E-17 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 CAK95_RS25330 37b564a3cfd28676d3eeb779b9e35989 136 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 27 134 1.3E-28 T 06-07-2017 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 CAK95_RS26865 96400a3677cec763093ac920497ade7b 888 Gene3D G3DSA:3.40.50.150 72 273 2.5E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26865 96400a3677cec763093ac920497ade7b 888 SUPERFAMILY SSF53335 74 276 4.29E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS26865 96400a3677cec763093ac920497ade7b 888 Pfam PF08242 Methyltransferase domain 92 190 1.0E-8 T 06-07-2017 IPR013217 Methyltransferase type 12 CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 Gene3D G3DSA:3.40.50.720 1 242 3.6E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 SUPERFAMILY SSF51735 1 245 6.48E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 Pfam PF00106 short chain dehydrogenase 6 196 2.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS15935 df46fff6e21d82d020012eb7b88c139f 300 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS19395 176880e7c5335f1558e197fae42d77b6 113 Gene3D G3DSA:1.10.260.40 16 75 3.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS19395 176880e7c5335f1558e197fae42d77b6 113 SUPERFAMILY SSF47413 19 74 6.19E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS23890 3d7190722acce57b30ed1eae519739be 215 Gene3D G3DSA:3.40.50.150 16 211 1.0E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS23890 3d7190722acce57b30ed1eae519739be 215 SUPERFAMILY SSF53335 16 210 2.15E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS23890 3d7190722acce57b30ed1eae519739be 215 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 208 3.1E-61 T 06-07-2017 CAK95_RS23890 3d7190722acce57b30ed1eae519739be 215 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 11 210 8.8E-64 T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAK95_RS23890 3d7190722acce57b30ed1eae519739be 215 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 213 37.991 T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAK95_RS08975 d45db385a715333b8cc19d5352cafb91 243 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 6 217 4.9E-26 T 06-07-2017 CAK95_RS28245 0b48f7693ccb7cf62a173621f7f394d3 193 Pfam PF13801 Heavy-metal resistance 33 175 2.8E-14 T 06-07-2017 IPR025961 Heavy-metal resistance protein CAK95_RS13150 50e55ea9e69b8ffefe82c3c2830e0eaf 272 Gene3D G3DSA:2.40.160.20 36 271 1.0E-32 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS13150 50e55ea9e69b8ffefe82c3c2830e0eaf 272 Pfam PF13505 Outer membrane protein beta-barrel domain 8 271 5.7E-20 T 06-07-2017 IPR027385 Outer membrane protein beta-barrel CAK95_RS13150 50e55ea9e69b8ffefe82c3c2830e0eaf 272 SUPERFAMILY SSF56925 36 272 7.32E-26 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAK95_RS14250 aea53bb136a5b8b7752332cdcbfcbdf3 333 Pfam PF04909 Amidohydrolase 3 329 1.3E-32 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS14250 aea53bb136a5b8b7752332cdcbfcbdf3 333 SUPERFAMILY SSF51556 3 330 1.15E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS14250 aea53bb136a5b8b7752332cdcbfcbdf3 333 Gene3D G3DSA:3.20.20.140 3 331 4.1E-70 T 06-07-2017 CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 Gene3D G3DSA:1.10.287.110 143 202 1.2E-10 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 Pfam PF00226 DnaJ domain 151 202 9.0E-10 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 SMART SM00271 148 206 8.7E-7 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 SUPERFAMILY SSF46565 144 202 2.49E-12 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 PRINTS PR00625 DnaJ domain signature 151 169 6.6E-5 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 PRINTS PR00625 DnaJ domain signature 169 184 6.6E-5 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS10525 82fa7106175ba0f92797decdac43aef5 207 PRINTS PR00625 DnaJ domain signature 186 206 6.6E-5 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS18030 58dba321827ab91b46ca47633bed8525 391 Pfam PF05762 VWA domain containing CoxE-like protein 186 272 1.4E-7 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 73 7.5E-15 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 SUPERFAMILY SSF47616 76 204 3.06E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 Gene3D G3DSA:1.20.1050.10 84 201 4.9E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 SUPERFAMILY SSF52833 1 81 2.61E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 Pfam PF13410 Glutathione S-transferase, C-terminal domain 135 187 2.7E-8 T 06-07-2017 CAK95_RS12035 e986ee7df81e6781bbe8bed3f1b70618 209 Gene3D G3DSA:3.40.30.10 1 83 4.2E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS12400 9caa13fcbc3713b7b364c17526a54e9c 206 SUPERFAMILY SSF52499 25 205 2.62E-42 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12400 9caa13fcbc3713b7b364c17526a54e9c 206 Gene3D G3DSA:3.40.50.850 29 205 6.1E-43 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12400 9caa13fcbc3713b7b364c17526a54e9c 206 Pfam PF00857 Isochorismatase family 28 201 4.4E-35 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 Gene3D G3DSA:1.20.1250.20 486 515 1.8E-16 T 06-07-2017 CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 Gene3D G3DSA:1.20.1250.20 274 422 1.8E-16 T 06-07-2017 CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 Gene3D G3DSA:1.20.1250.20 2 179 4.3E-22 T 06-07-2017 CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 SUPERFAMILY SSF103473 2 183 8.72E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 SUPERFAMILY SSF103473 249 421 8.72E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS21900 7b15d4f009365c5d39f0253b1a32b768 527 Pfam PF07690 Major Facilitator Superfamily 4 411 4.6E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1142 6.0E-253 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 SUPERFAMILY SSF75553 495 644 7.32E-5 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1135 3.1E-59 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 Gene3D G3DSA:3.40.50.300 1 166 6.7E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 Gene3D G3DSA:3.40.50.300 989 1146 6.7E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1144 20.974 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 SUPERFAMILY SSF52540 941 1143 7.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS11300 ff8cf7193e350fc36507e9d690d4aa9c 1155 SUPERFAMILY SSF52540 1 210 7.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS09830 1a27290b1d2325a8618a79dc0a1dc2bf 274 SUPERFAMILY SSF56281 6 274 1.31E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09830 1a27290b1d2325a8618a79dc0a1dc2bf 274 SMART SM00849 28 217 2.8E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09830 1a27290b1d2325a8618a79dc0a1dc2bf 274 Pfam PF12706 Beta-lactamase superfamily domain 41 240 1.5E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09830 1a27290b1d2325a8618a79dc0a1dc2bf 274 Gene3D G3DSA:3.60.15.10 6 274 2.2E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS20730 3d1ecc3d9d7f030d7fa278bce83cbe7b 176 Gene3D G3DSA:2.160.10.10 18 171 1.2E-45 T 06-07-2017 CAK95_RS20730 3d1ecc3d9d7f030d7fa278bce83cbe7b 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 90 124 6.6E-9 T 06-07-2017 IPR001451 Hexapeptide repeat CAK95_RS20730 3d1ecc3d9d7f030d7fa278bce83cbe7b 176 SUPERFAMILY SSF51161 11 171 7.62E-48 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK95_RS22920 c6bd36f4092d2fd453061ad06e7341a9 77 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 6 67 3.0E-5 T 06-07-2017 IPR018691 Protein of unknown function DUF2188 CAK95_RS13970 c4c8ce1ebcb083e9bba4065591c4b466 281 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 9 210 7.2E-22 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK95_RS13970 c4c8ce1ebcb083e9bba4065591c4b466 281 Gene3D G3DSA:2.60.120.620 8 220 2.0E-27 T 06-07-2017 CAK95_RS13970 c4c8ce1ebcb083e9bba4065591c4b466 281 SUPERFAMILY SSF51197 8 222 1.81E-34 T 06-07-2017 CAK95_RS03045 dff91ceda361be967f8db08384419881 292 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 30 254 2.4E-32 T 06-07-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CAK95_RS25645 fe04a32bae89ad747c70146459c12d87 139 SUPERFAMILY SSF51182 24 113 2.34E-7 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS25645 fe04a32bae89ad747c70146459c12d87 139 Gene3D G3DSA:2.60.120.10 25 107 1.3E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS27845 e0fc34e05af245609c18af39ba864fa0 229 Pfam PF11748 Protein of unknown function (DUF3306) 7 123 7.3E-25 T 06-07-2017 IPR021735 Protein of unknown function DUF3306 CAK95_RS15285 bd603f945e0ff94642477d88a37d1b0c 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 4.5E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15285 bd603f945e0ff94642477d88a37d1b0c 329 PIRSF PIRSF017082 3 325 1.0E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15285 bd603f945e0ff94642477d88a37d1b0c 329 SUPERFAMILY SSF53850 113 284 5.27E-8 T 06-07-2017 CAK95_RS12735 e7be0a8301262775264c7a4cd12dde91 167 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 22 157 2.7E-18 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS16285 b6fd39303ee4cd116a5f2fe97de80509 294 PIRSF PIRSF000103 1 294 1.0E-35 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK95_RS16285 b6fd39303ee4cd116a5f2fe97de80509 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 164 3.7E-18 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK95_RS16285 b6fd39303ee4cd116a5f2fe97de80509 294 SUPERFAMILY SSF51735 6 164 9.98E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS16285 b6fd39303ee4cd116a5f2fe97de80509 294 Gene3D G3DSA:3.40.50.720 4 165 6.1E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS26675 65cb8f047dc955f66fdcd4e9729d169d 113 Pfam PF06823 Protein of unknown function (DUF1236) 48 113 1.6E-19 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 207.183 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Gene3D G3DSA:3.90.170.10 264 422 2.7E-68 T 06-07-2017 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 SUPERFAMILY SSF52540 1 422 7.12E-169 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 3.0E-154 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Gene3D G3DSA:1.10.300.10 102 193 2.5E-25 T 06-07-2017 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 SMART SM00788 3 421 6.1E-281 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.6E-168 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Gene3D G3DSA:3.40.440.10 1 93 9.6E-69 T 06-07-2017 CAK95_RS28120 42cda764015612b3366d9b95c77bf48a 428 Gene3D G3DSA:3.40.440.10 194 263 9.6E-69 T 06-07-2017 CAK95_RS04760 ec62cdbad52209b8f7b48d082bcfe62d 332 SUPERFAMILY SSF53335 50 210 1.19E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS04760 ec62cdbad52209b8f7b48d082bcfe62d 332 Gene3D G3DSA:3.40.50.150 41 169 3.0E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS04760 ec62cdbad52209b8f7b48d082bcfe62d 332 Gene3D G3DSA:3.40.50.150 204 216 3.0E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS04760 ec62cdbad52209b8f7b48d082bcfe62d 332 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 49 319 2.4E-93 T 06-07-2017 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 CAK95_RS16535 220f4b46abe9ce940da169a66206a666 41 SUPERFAMILY SSF57840 1 41 7.85E-12 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS16535 220f4b46abe9ce940da169a66206a666 41 Pfam PF00444 Ribosomal protein L36 1 41 3.7E-15 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS16535 220f4b46abe9ce940da169a66206a666 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS16535 220f4b46abe9ce940da169a66206a666 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 3.3E-6 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS16535 220f4b46abe9ce940da169a66206a666 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 15.38 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS12110 64c8ad786ed0bdb3170aad2fe731b198 301 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 36 2.4E-15 T 06-07-2017 IPR011723 Zinc finger/thioredoxin putative CAK95_RS12110 64c8ad786ed0bdb3170aad2fe731b198 301 Pfam PF13717 zinc-ribbon domain 1 36 3.4E-13 T 06-07-2017 CAK95_RS27910 b93657150eaba8ceaecf0e4c5341b174 293 PIRSF PIRSF011468 1 284 1.2E-158 T 06-07-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 CAK95_RS27910 b93657150eaba8ceaecf0e4c5341b174 293 Pfam PF06007 Phosphonate metabolism protein PhnJ 5 275 1.2E-146 T 06-07-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 CAK95_RS14625 dd8fc055a92637bd298e3c8581adbbb4 61 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 59 1.7E-18 T 06-07-2017 IPR019201 Protein of unknown function DUF2065 CAK95_RS08625 0bbec400621fafff7b582feae9aee929 254 SUPERFAMILY SSF52540 89 191 1.72E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08625 0bbec400621fafff7b582feae9aee929 254 SUPERFAMILY SSF52540 3 37 1.72E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08625 0bbec400621fafff7b582feae9aee929 254 Gene3D G3DSA:3.40.50.300 7 45 1.3E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS08625 0bbec400621fafff7b582feae9aee929 254 Gene3D G3DSA:3.40.50.300 79 192 1.3E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 SUPERFAMILY SSF54373 270 363 4.32E-12 T 06-07-2017 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Gene3D G3DSA:3.30.9.10 135 189 8.6E-8 T 06-07-2017 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Gene3D G3DSA:3.30.9.10 269 356 8.6E-8 T 06-07-2017 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Pfam PF01266 FAD dependent oxidoreductase 3 400 3.8E-62 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 SUPERFAMILY SSF51905 363 418 3.69E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 SUPERFAMILY SSF51905 1 55 3.69E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 SUPERFAMILY SSF51905 106 270 3.69E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Gene3D G3DSA:3.40.50.720 3 97 3.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Gene3D G3DSA:3.40.50.720 357 418 3.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS04605 1a05d84c58f30d1d9658abd225c0e567 420 Gene3D G3DSA:3.40.50.720 190 268 3.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21920 fef2c8aafa460e3123db42ffc1e6570d 304 Pfam PF09140 ATPase MipZ 12 274 1.7E-112 T 06-07-2017 IPR015223 ATPase MipZ CAK95_RS21920 fef2c8aafa460e3123db42ffc1e6570d 304 Gene3D G3DSA:3.40.50.300 9 244 1.9E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS21920 fef2c8aafa460e3123db42ffc1e6570d 304 SUPERFAMILY SSF52540 11 247 9.65E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS00220 938a17387bbb3b9f96118096be6eb54c 508 SUPERFAMILY SSF53323 17 232 3.53E-7 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK95_RS00220 938a17387bbb3b9f96118096be6eb54c 508 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 25 214 7.6E-11 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK95_RS28815 ae34eb8329540cabdb621537ebffaad3 389 SUPERFAMILY SSF51679 30 378 1.31E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS28815 ae34eb8329540cabdb621537ebffaad3 389 Pfam PF00296 Luciferase-like monooxygenase 43 340 6.3E-45 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS28815 ae34eb8329540cabdb621537ebffaad3 389 Gene3D G3DSA:3.20.20.30 32 377 9.9E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK95_RS00835 76ef4f1e1e94af9e0dc1b132ccba36ee 339 SUPERFAMILY SSF51556 6 330 1.15E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00835 76ef4f1e1e94af9e0dc1b132ccba36ee 339 Gene3D G3DSA:3.20.20.140 6 331 3.0E-76 T 06-07-2017 CAK95_RS00835 76ef4f1e1e94af9e0dc1b132ccba36ee 339 Pfam PF04909 Amidohydrolase 8 310 7.8E-39 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 Pfam PF00209 Sodium:neurotransmitter symporter family 155 445 2.3E-30 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 Pfam PF00209 Sodium:neurotransmitter symporter family 11 120 6.5E-25 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 92 118 2.9E-14 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 17 38 2.9E-14 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 46 65 2.9E-14 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 345 364 2.9E-14 T 06-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAK95_RS06480 76509702cbfd58f944c1793eb907e366 448 SUPERFAMILY SSF161070 11 447 1.83E-121 T 06-07-2017 CAK95_RS18050 ae23c0b5a94d071601a55947d28283cf 343 SUPERFAMILY SSF53850 47 296 1.17E-6 T 06-07-2017 CAK95_RS18050 ae23c0b5a94d071601a55947d28283cf 343 PIRSF PIRSF017082 9 342 1.7E-48 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS18050 ae23c0b5a94d071601a55947d28283cf 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 339 2.9E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 17 272 1.2E-117 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 Gene3D G3DSA:3.40.50.720 9 271 5.7E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 270 3.4E-60 T 06-07-2017 CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 SUPERFAMILY SSF51735 16 271 9.12E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 2.6E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 2.6E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS21745 5c053b97e8cb17bec789b25bb830be6b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 2.6E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK95_RS28465 57f5314ee7051e60612c842ea64cf9dc 577 Gene3D G3DSA:3.30.1380.10 93 215 1.4E-26 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS28465 57f5314ee7051e60612c842ea64cf9dc 577 Pfam PF05951 Bacterial protein of unknown function (DUF882) 61 213 6.2E-65 T 06-07-2017 IPR010275 Protein of unknown function DUF882 CAK95_RS28465 57f5314ee7051e60612c842ea64cf9dc 577 SUPERFAMILY SSF55166 88 218 1.77E-32 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK95_RS19730 8308899b6314062acd202712378d9803 159 Pfam PF04214 Protein of unknown function, DUF 58 124 4.0E-32 T 06-07-2017 IPR007332 Protein of unknown function DUF411 CAK95_RS13780 de56420748050eedd065b811f3c0bb04 133 Pfam PF07681 DoxX 15 91 8.6E-14 T 06-07-2017 IPR032808 DoxX family CAK95_RS17290 e333294a052f99364fcb03b299db6f71 438 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 40 405 5.8E-166 T 06-07-2017 IPR017777 ABC transporter, urea, substrate-binding, UrtA CAK95_RS17290 e333294a052f99364fcb03b299db6f71 438 SUPERFAMILY SSF53822 39 406 1.21E-85 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS17290 e333294a052f99364fcb03b299db6f71 438 Gene3D G3DSA:3.40.50.2300 155 347 1.0E-68 T 06-07-2017 CAK95_RS17290 e333294a052f99364fcb03b299db6f71 438 Pfam PF13433 Periplasmic binding protein domain 40 407 1.2E-164 T 06-07-2017 CAK95_RS24520 4e95060376d397b5982d9d409208ab20 288 Pfam PF05063 MT-A70 48 216 8.5E-26 T 06-07-2017 IPR007757 MT-A70-like GO:0006139|GO:0008168 CAK95_RS24520 4e95060376d397b5982d9d409208ab20 288 SUPERFAMILY SSF53335 34 228 5.35E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00850 7a5ebcf9cfe857ac9b86ebbb8c5cdc5b 150 Pfam PF07681 DoxX 22 101 1.2E-7 T 06-07-2017 IPR032808 DoxX family CAK95_RS01280 97fd857850e492e7c9a2b0a9150992f4 283 Pfam PF11769 Protein of unknown function (DUF3313) 19 211 1.1E-42 T 06-07-2017 IPR021747 Protein of unknown function DUF3313 CAK95_RS05530 031965c0caa5fb5a85eb0f15f475ce3d 160 Hamap MF_01398 ATP synthase subunit b [atpF]. 2 159 11.541 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK95_RS05530 031965c0caa5fb5a85eb0f15f475ce3d 160 Pfam PF00430 ATP synthase B/B' CF(0) 6 135 7.2E-27 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK95_RS01375 2ab304c8d366f82a201316cf83613d2c 236 SUPERFAMILY SSF52833 61 233 1.03E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01375 2ab304c8d366f82a201316cf83613d2c 236 Gene3D G3DSA:3.40.30.10 63 233 3.7E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS01375 2ab304c8d366f82a201316cf83613d2c 236 Pfam PF00578 AhpC/TSA family 64 208 2.0E-19 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS24080 3e061eda2b6f964774d5dd1b48f25270 240 Pfam PF10691 Protein of unknown function (DUF2497) 172 238 5.1E-27 T 06-07-2017 IPR019632 Protein of unknown function DUF2497 CAK95_RS07040 903d5ca75ee1f58425592ee12622647a 259 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 1 259 39.575 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CAK95_RS07040 903d5ca75ee1f58425592ee12622647a 259 SUPERFAMILY SSF140959 2 259 1.83E-96 T 06-07-2017 CAK95_RS07040 903d5ca75ee1f58425592ee12622647a 259 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 1 259 8.5E-120 T 06-07-2017 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 CAK95_RS07040 903d5ca75ee1f58425592ee12622647a 259 Pfam PF03301 Tryptophan 2,3-dioxygenase 1 133 5.8E-41 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CAK95_RS07040 903d5ca75ee1f58425592ee12622647a 259 Pfam PF03301 Tryptophan 2,3-dioxygenase 176 258 3.2E-23 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CAK95_RS26175 af8b3f25c51eea3964abb7ba91cda75e 173 Pfam PF16694 Cytochrome P460 46 169 3.6E-35 T 06-07-2017 IPR032033 Cytochrome P460 CAK95_RS20920 2558e234bda4ec37b6609906352fc8d0 199 Gene3D G3DSA:1.25.40.10 99 175 2.0E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS20920 2558e234bda4ec37b6609906352fc8d0 199 SUPERFAMILY SSF48452 94 179 1.97E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS18775 fe3e5700bbbdcf02c9ba215169c1e8eb 503 SUPERFAMILY SSF56935 246 330 4.03E-5 T 06-07-2017 CAK95_RS18775 fe3e5700bbbdcf02c9ba215169c1e8eb 503 SUPERFAMILY SSF56935 54 205 4.03E-5 T 06-07-2017 CAK95_RS18775 fe3e5700bbbdcf02c9ba215169c1e8eb 503 SUPERFAMILY SSF56935 367 481 4.03E-5 T 06-07-2017 CAK95_RS18775 fe3e5700bbbdcf02c9ba215169c1e8eb 503 Pfam PF02530 Porin subfamily 25 466 5.0E-80 T 06-07-2017 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 CAK95_RS02320 8262c9d8b1230026d3b582858e7f952f 332 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 103 313 2.3E-88 T 06-07-2017 IPR014142 P-type conjugative transfer protein TrbG CAK95_RS02320 8262c9d8b1230026d3b582858e7f952f 332 Pfam PF03524 Conjugal transfer protein 102 325 1.6E-68 T 06-07-2017 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CAK95_RS27760 8d1369b92f5a54f2e8a40204fb749285 257 SMART SM00382 28 222 1.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS27760 8d1369b92f5a54f2e8a40204fb749285 257 Pfam PF00005 ABC transporter 20 173 1.8E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS27760 8d1369b92f5a54f2e8a40204fb749285 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 4.8E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK95_RS27760 8d1369b92f5a54f2e8a40204fb749285 257 SUPERFAMILY SSF52540 3 244 2.49E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS27760 8d1369b92f5a54f2e8a40204fb749285 257 Gene3D G3DSA:3.40.50.300 3 242 1.7E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS07805 87a493882a621fab254d4093f5aa2439 223 TIGRFAM TIGR03784 marine_sortase: sortase, marine proteobacterial type 17 187 8.5E-61 T 06-07-2017 IPR022445 Sortase, proteobacterial type CAK95_RS07805 87a493882a621fab254d4093f5aa2439 223 SUPERFAMILY SSF63817 55 191 3.92E-21 T 06-07-2017 IPR023365 Sortase domain CAK95_RS07805 87a493882a621fab254d4093f5aa2439 223 TIGRFAM TIGR01076 sortase_fam: sortase 67 188 7.3E-14 T 06-07-2017 IPR005754 Sortase family CAK95_RS07805 87a493882a621fab254d4093f5aa2439 223 Gene3D G3DSA:2.40.260.10 63 191 1.4E-12 T 06-07-2017 IPR023365 Sortase domain CAK95_RS07805 87a493882a621fab254d4093f5aa2439 223 Pfam PF04203 Sortase family 68 190 3.0E-20 T 06-07-2017 IPR005754 Sortase family CAK95_RS07045 b09b9714ca2ad4633c3bb5057c59211c 402 Pfam PF01734 Patatin-like phospholipase 81 266 1.5E-22 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK95_RS07045 b09b9714ca2ad4633c3bb5057c59211c 402 Gene3D G3DSA:3.40.1090.10 76 265 5.5E-14 T 06-07-2017 CAK95_RS07045 b09b9714ca2ad4633c3bb5057c59211c 402 SUPERFAMILY SSF52151 78 268 1.18E-31 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK95_RS18945 5758adf0fafd7fba919ab040e04a612b 127 Gene3D G3DSA:1.10.260.40 44 117 9.0E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS18945 5758adf0fafd7fba919ab040e04a612b 127 Pfam PF01381 Helix-turn-helix 66 115 3.0E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS18945 5758adf0fafd7fba919ab040e04a612b 127 SUPERFAMILY SSF47413 58 116 1.07E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS18945 5758adf0fafd7fba919ab040e04a612b 127 SMART SM00530 62 116 0.0025 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK95_RS28235 cab4c191fa00419ea5a5e57bf9474728 333 Pfam PF00701 Dihydrodipicolinate synthetase family 14 117 1.4E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS28235 cab4c191fa00419ea5a5e57bf9474728 333 SUPERFAMILY SSF51569 11 320 1.78E-37 T 06-07-2017 CAK95_RS28235 cab4c191fa00419ea5a5e57bf9474728 333 Gene3D G3DSA:3.20.20.70 14 321 4.1E-41 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS28235 cab4c191fa00419ea5a5e57bf9474728 333 SMART SM01130 9 320 7.6E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK95_RS15090 73cbf206a75d43fb240cc851cd8288f1 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 312 1.6E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS19625 c22dafcdf6346cb51951c0fc1f238a3a 334 Pfam PF03524 Conjugal transfer protein 104 327 1.9E-67 T 06-07-2017 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CAK95_RS19625 c22dafcdf6346cb51951c0fc1f238a3a 334 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 105 315 1.2E-87 T 06-07-2017 IPR014142 P-type conjugative transfer protein TrbG CAK95_RS16360 ede2056b57b91b2d19a50ffdf2243631 325 SUPERFAMILY SSF53850 111 287 1.5E-14 T 06-07-2017 CAK95_RS16360 ede2056b57b91b2d19a50ffdf2243631 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 9.1E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS16360 ede2056b57b91b2d19a50ffdf2243631 325 PIRSF PIRSF017082 3 324 4.3E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS27195 a51cc9b812fe70c565f0272d6c0e3abb 337 SUPERFAMILY SSF53850 111 285 2.08E-5 T 06-07-2017 CAK95_RS27195 a51cc9b812fe70c565f0272d6c0e3abb 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 307 1.4E-46 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS13615 f599a1b2a9f8b79ab461e417bfb770b9 423 Pfam PF13557 Putative MetA-pathway of phenol degradation 179 423 5.8E-19 T 06-07-2017 IPR025737 MetA-pathway of phenol degradation, putative CAK95_RS23015 de684d385e483de30e51ccd7947da048 289 Pfam PF06230 Protein of unknown function (DUF1009) 65 282 4.9E-68 T 06-07-2017 IPR010415 Protein of unknown function DUF1009 CAK95_RS20975 f0b4174eacf791c762d959f462990154 509 Pfam PF01594 Domain of unknown function DUF20 179 499 6.4E-42 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAK95_RS25550 6db023de8eb7532adb3e5457a26c1d4d 155 Pfam PF13787 Protein of unknown function with HXXEE motif 8 110 6.6E-15 T 06-07-2017 IPR025671 Protein of unknown function with HXXEE motif CAK95_RS21930 e864556d600b1cf46e4fe4ddd81b180f 232 SUPERFAMILY SSF46565 174 229 5.23E-15 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS21930 e864556d600b1cf46e4fe4ddd81b180f 232 Gene3D G3DSA:1.10.287.110 173 228 6.8E-18 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS21930 e864556d600b1cf46e4fe4ddd81b180f 232 SMART SM00271 178 232 3.6E-11 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS21930 e864556d600b1cf46e4fe4ddd81b180f 232 Pfam PF00226 DnaJ domain 180 211 1.6E-7 T 06-07-2017 IPR001623 DnaJ domain CAK95_RS26895 207eda1b9cf94c576fdf75fad354ca89 410 Pfam PF02706 Chain length determinant protein 52 200 5.6E-5 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAK95_RS03390 d7bc94a3917fec9c18b6341b7a846d61 99 Pfam PF07235 Protein of unknown function (DUF1427) 2 81 1.6E-35 T 06-07-2017 IPR009872 Protein of unknown function DUF1427 CAK95_RS03390 d7bc94a3917fec9c18b6341b7a846d61 99 TIGRFAM TIGR03510 XapX: XapX domain 4 49 1.1E-18 T 06-07-2017 IPR020017 XapX domain CAK95_RS11275 25b3e4491879e827226d2d33f229f9a7 83 Pfam PF04226 Transglycosylase associated protein 36 83 1.2E-12 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS11180 ad0792572ae0b5f1957c56833feacbf6 465 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 434 9.9E-154 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAK95_RS11180 ad0792572ae0b5f1957c56833feacbf6 465 PIRSF PIRSF006446 1 453 7.7E-176 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAK95_RS25320 0c64b3ac46389f4023c71ebbea9a6b20 206 Gene3D G3DSA:1.10.10.10 40 151 2.7E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25320 0c64b3ac46389f4023c71ebbea9a6b20 206 Pfam PF13463 Winged helix DNA-binding domain 63 127 3.7E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK95_RS25320 0c64b3ac46389f4023c71ebbea9a6b20 206 PIRSF PIRSF036158 1 180 1.4E-69 T 06-07-2017 IPR014601 Transcriptional regulator with MarR-type HTH domain CAK95_RS25320 0c64b3ac46389f4023c71ebbea9a6b20 206 SUPERFAMILY SSF46785 34 150 1.01E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS25180 71591673185c80310968003b335ed157 403 PIRSF PIRSF020818 1 403 3.6E-173 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAK95_RS25180 71591673185c80310968003b335ed157 403 Pfam PF06850 PHB de-polymerase C-terminus 201 400 3.7E-92 T 06-07-2017 IPR009656 PHB de-polymerase, C-terminal CAK95_RS25180 71591673185c80310968003b335ed157 403 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 26 399 6.7E-160 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAK95_RS25180 71591673185c80310968003b335ed157 403 Gene3D G3DSA:3.40.50.1820 95 383 9.4E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25180 71591673185c80310968003b335ed157 403 SUPERFAMILY SSF53474 94 397 3.67E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS06345 cf7774bad7058345ecd01cdee38e9b19 163 PIRSF PIRSF031796 1 161 2.6E-68 T 06-07-2017 IPR009394 DNA repair protein MmcB-like CAK95_RS06345 cf7774bad7058345ecd01cdee38e9b19 163 Pfam PF06319 Protein of unknown function (DUF1052) 13 154 5.4E-67 T 06-07-2017 IPR009394 DNA repair protein MmcB-like CAK95_RS03345 eee05d64824d806f6cc3e03a98bcf49c 360 Gene3D G3DSA:3.40.190.10 100 263 5.8E-14 T 06-07-2017 CAK95_RS03345 eee05d64824d806f6cc3e03a98bcf49c 360 SUPERFAMILY SSF53850 28 294 6.25E-14 T 06-07-2017 CAK95_RS11335 e483114d91bdf03ff6644a0d1b943de1 126 Pfam PF13356 Domain of unknown function (DUF4102) 4 64 8.4E-8 T 06-07-2017 IPR025166 Domain of unknown function DUF4102 CAK95_RS03115 07c13814ceaaad99185e52fcfeda3f49 70 Gene3D G3DSA:3.30.1580.10 3 61 8.7E-5 T 06-07-2017 IPR004174 Head-to-tail joining protein W, GpW GO:0019058 CAK95_RS15450 e22f3a5c876d916eb04fdcd00c9e1491 154 Gene3D G3DSA:1.20.1260.10 14 97 1.3E-21 T 06-07-2017 IPR012347 Ferritin-related CAK95_RS15450 e22f3a5c876d916eb04fdcd00c9e1491 154 Pfam PF03713 Domain of unknown function (DUF305) 19 97 3.9E-18 T 06-07-2017 IPR005183 Domain of unknown function DUF305 CAK95_RS01550 ed068d68ca50ed27622cf517c2926db0 73 SUPERFAMILY SSF54001 1 36 2.13E-6 T 06-07-2017 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 Pfam PF00561 alpha/beta hydrolase fold 71 319 2.8E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 111 4.4E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00111 Alpha/beta hydrolase fold signature 141 154 4.4E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00111 Alpha/beta hydrolase fold signature 155 168 4.4E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00111 Alpha/beta hydrolase fold signature 264 278 4.4E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 Gene3D G3DSA:3.40.50.1820 33 332 9.2E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 SUPERFAMILY SSF53474 50 335 2.37E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00412 Epoxide hydrolase signature 76 94 1.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00412 Epoxide hydrolase signature 96 111 1.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00412 Epoxide hydrolase signature 141 154 1.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00412 Epoxide hydrolase signature 311 333 1.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS12955 39ed80c5e0475df58848b8a2f7c17132 338 PRINTS PR00412 Epoxide hydrolase signature 155 168 1.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK95_RS12800 a2dd94d074c19a36affde94b164ffaf2 270 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 8 257 2.7E-56 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAK95_RS12800 a2dd94d074c19a36affde94b164ffaf2 270 Gene3D G3DSA:3.60.130.10 4 264 4.0E-79 T 06-07-2017 CAK95_RS12800 a2dd94d074c19a36affde94b164ffaf2 270 SUPERFAMILY SSF51197 6 264 8.7E-75 T 06-07-2017 CAK95_RS19605 ad51975d78eb5364ef554765cf872286 245 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 8 244 5.4E-55 T 06-07-2017 IPR014147 Type IV conjugative transfer protein TrbJ CAK95_RS07220 05c7a11e101b9cbd7652d11e3c832e32 416 Gene3D G3DSA:3.40.50.2000 1 251 1.7E-68 T 06-07-2017 CAK95_RS07220 05c7a11e101b9cbd7652d11e3c832e32 416 Gene3D G3DSA:3.40.50.2000 252 388 1.5E-11 T 06-07-2017 CAK95_RS07220 05c7a11e101b9cbd7652d11e3c832e32 416 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 236 379 3.0E-9 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAK95_RS07220 05c7a11e101b9cbd7652d11e3c832e32 416 SUPERFAMILY SSF53756 1 410 3.84E-96 T 06-07-2017 CAK95_RS07220 05c7a11e101b9cbd7652d11e3c832e32 416 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 138 1.7E-15 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK95_RS12350 abaebd40d90e11fd939fed87f5238110 230 Gene3D G3DSA:3.90.850.10 98 210 1.8E-5 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS12350 abaebd40d90e11fd939fed87f5238110 230 SUPERFAMILY SSF56529 46 213 5.1E-14 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS12350 abaebd40d90e11fd939fed87f5238110 230 Pfam PF11010 Protein of unknown function (DUF2848) 29 221 2.9E-81 T 06-07-2017 IPR021269 Protein of unknown function DUF2848 CAK95_RS24935 b3949a9a44d943949d317dbd338ab169 378 Pfam PF12704 MacB-like periplasmic core domain 16 232 2.5E-12 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAK95_RS24935 b3949a9a44d943949d317dbd338ab169 378 Pfam PF02687 FtsX-like permease family 263 372 1.9E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK95_RS03760 d41f18d7c9950c572f73db6ca1245852 171 SUPERFAMILY SSF52833 35 170 1.18E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS03760 d41f18d7c9950c572f73db6ca1245852 171 Gene3D G3DSA:3.40.30.10 11 170 1.5E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS03760 d41f18d7c9950c572f73db6ca1245852 171 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK95_RS03760 d41f18d7c9950c572f73db6ca1245852 171 Pfam PF00578 AhpC/TSA family 36 150 1.6E-25 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK95_RS18230 62c2f5e210deed74ce1fd6dd1b1f811c 288 Gene3D G3DSA:1.25.60.10 196 259 1.1E-5 T 06-07-2017 CAK95_RS18230 62c2f5e210deed74ce1fd6dd1b1f811c 288 SUPERFAMILY SSF158791 199 261 1.7E-5 T 06-07-2017 CAK95_RS24400 f9a6f025f7b60895d34db9c96e35289c 781 Gene3D G3DSA:2.60.40.1120 9 87 3.9E-6 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain CAK95_RS24400 f9a6f025f7b60895d34db9c96e35289c 781 SUPERFAMILY SSF49464 9 88 8.24E-5 T 06-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain CAK95_RS24400 f9a6f025f7b60895d34db9c96e35289c 781 SUPERFAMILY SSF51126 378 573 5.78E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS24400 f9a6f025f7b60895d34db9c96e35289c 781 SUPERFAMILY SSF51126 228 349 5.78E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAK95_RS08280 73fc6fc12d5241ed0ca69f144d4ebe6b 202 Pfam PF04191 Phospholipid methyltransferase 67 136 7.0E-12 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS06965 746ab84ab9b71f773474d108ab2a90c1 194 Pfam PF06930 Protein of unknown function (DUF1282) 14 175 1.2E-12 T 06-07-2017 IPR009698 Protein of unknown function DUF1282 CAK95_RS05405 9c7e36c6c69499444241e65a81b7779a 123 Pfam PF06568 Domain of unknown function (DUF1127) 29 63 4.0E-10 T 06-07-2017 IPR009506 Protein of unknown function DUF1127 CAK95_RS26550 f428088627582241ab0c7591ebbcda45 375 PIRSF PIRSF031854 4 352 7.3E-125 T 06-07-2017 IPR022550 Nucleotidyltransferase 8 CAK95_RS26550 f428088627582241ab0c7591ebbcda45 375 Pfam PF12281 Nucleotidyltransferase 109 323 9.6E-74 T 06-07-2017 IPR022550 Nucleotidyltransferase 8 CAK95_RS21540 9ca68a4eeb6c5c9a19f82f718d735d9b 227 Pfam PF01965 DJ-1/PfpI family 2 162 1.5E-27 T 06-07-2017 IPR002818 DJ-1/PfpI CAK95_RS21540 9ca68a4eeb6c5c9a19f82f718d735d9b 227 SUPERFAMILY SSF52317 1 185 2.99E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS21540 9ca68a4eeb6c5c9a19f82f718d735d9b 227 Gene3D G3DSA:3.40.50.880 1 210 6.6E-67 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK95_RS10705 8cc654271b3fce588de9fb6b971e0285 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 273 8.7E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05015 e7f62187f3da4d60a0f522feebb4ff6f 221 Pfam PF04191 Phospholipid methyltransferase 81 150 4.0E-10 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS26815 b00220edf4a59f6ec0a72845134d2c6b 434 Pfam PF13692 Glycosyl transferases group 1 258 396 2.7E-17 T 06-07-2017 CAK95_RS26815 b00220edf4a59f6ec0a72845134d2c6b 434 Gene3D G3DSA:3.40.50.2000 247 400 1.2E-14 T 06-07-2017 CAK95_RS26815 b00220edf4a59f6ec0a72845134d2c6b 434 SUPERFAMILY SSF53756 154 432 3.04E-38 T 06-07-2017 CAK95_RS06875 a5f368bb0cc0d2b5052d845e8ab6c062 229 Pfam PF13649 Methyltransferase domain 51 144 3.3E-12 T 06-07-2017 CAK95_RS06875 a5f368bb0cc0d2b5052d845e8ab6c062 229 Gene3D G3DSA:3.40.50.150 14 228 6.8E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS06875 a5f368bb0cc0d2b5052d845e8ab6c062 229 SUPERFAMILY SSF53335 16 228 1.34E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS13985 cba34d8ef442cd0882704d0e46d920f3 129 Pfam PF10990 Protein of unknown function (DUF2809) 29 112 1.8E-24 T 06-07-2017 IPR021257 Protein of unknown function DUF2809 CAK95_RS02780 d5036fe25c121c57f0529392461577ae 259 Pfam PF04773 FecR protein 61 159 5.0E-14 T 06-07-2017 IPR006860 FecR protein CAK95_RS18545 e63cf70daae5ed536b84a9a4ee10c60e 448 SUPERFAMILY SSF53850 232 321 5.97E-5 T 06-07-2017 CAK95_RS18545 e63cf70daae5ed536b84a9a4ee10c60e 448 SUPERFAMILY SSF53850 95 194 5.97E-5 T 06-07-2017 CAK95_RS18545 e63cf70daae5ed536b84a9a4ee10c60e 448 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 107 373 1.6E-21 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS07870 c0db516a6b0fd4a31efd5f9e61ce6830 263 Gene3D G3DSA:2.150.10.10 154 250 3.0E-5 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAK95_RS28750 5e1c66203fdc83806d48bdd2a9223b78 314 Gene3D G3DSA:3.40.190.10 102 232 1.2E-16 T 06-07-2017 CAK95_RS28750 5e1c66203fdc83806d48bdd2a9223b78 314 SUPERFAMILY SSF53850 25 251 6.72E-39 T 06-07-2017 CAK95_RS28750 5e1c66203fdc83806d48bdd2a9223b78 314 Pfam PF09084 NMT1/THI5 like 28 243 4.2E-52 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS03915 684305567e878473a34daddb34dc0027 243 Pfam PF03591 AzlC protein 31 173 1.2E-33 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 Pfam PF00691 OmpA family 106 190 2.7E-16 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 PRINTS PR01021 OMPA domain signature 107 129 1.3E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 PRINTS PR01021 OMPA domain signature 154 170 1.3E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 PRINTS PR01021 OMPA domain signature 139 154 1.3E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 SUPERFAMILY SSF103088 101 207 1.11E-23 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS06830 176c701128a5e65a00bc47d10b243f0d 211 Gene3D G3DSA:3.30.1330.60 94 207 1.1E-24 T 06-07-2017 IPR006665 OmpA-like domain CAK95_RS27850 c12581f44889930f8539f71d66e7b0d5 176 Pfam PF11749 Protein of unknown function (DUF3305) 9 148 1.7E-33 T 06-07-2017 IPR021736 Protein of unknown function DUF3305 CAK95_RS01200 51c7503528fea9c5d31b2d89ece92d5f 163 Gene3D G3DSA:2.30.110.10 1 141 1.6E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS01200 51c7503528fea9c5d31b2d89ece92d5f 163 SMART SM00903 1 142 4.9E-41 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS01200 51c7503528fea9c5d31b2d89ece92d5f 163 SUPERFAMILY SSF50475 1 141 4.02E-36 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK95_RS01200 51c7503528fea9c5d31b2d89ece92d5f 163 Pfam PF01613 Flavin reductase like domain 1 141 1.3E-31 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK95_RS24900 8f5575aa4ea44801446b60ca3617a05f 342 Pfam PF15887 Putative zinc-binding metallo-peptidase 103 173 6.1E-10 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CAK95_RS07545 92dfe773f45119d3018c0f0653c7d7d0 175 SUPERFAMILY SSF55729 6 169 1.65E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS07545 92dfe773f45119d3018c0f0653c7d7d0 175 Gene3D G3DSA:3.40.630.30 5 171 2.0E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS07545 92dfe773f45119d3018c0f0653c7d7d0 175 Pfam PF13420 Acetyltransferase (GNAT) domain 7 161 8.6E-24 T 06-07-2017 CAK95_RS28400 4b80cfc9c727ee90b83475e9a1dc2193 103 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 98 2.3E-36 T 06-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK95_RS11635 fe932a7925858c447e156385ee59e6a6 149 SUPERFAMILY SSF50346 42 104 1.02E-11 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS11635 fe932a7925858c447e156385ee59e6a6 149 Pfam PF05239 PRC-barrel domain 44 107 2.9E-12 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS11635 fe932a7925858c447e156385ee59e6a6 149 Gene3D G3DSA:2.30.30.240 43 105 2.3E-10 T 06-07-2017 CAK95_RS15380 6c53212c7d715b66ce1466233be70b81 215 Pfam PF08241 Methyltransferase domain 50 145 2.8E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK95_RS15380 6c53212c7d715b66ce1466233be70b81 215 Gene3D G3DSA:3.40.50.150 14 186 6.6E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15380 6c53212c7d715b66ce1466233be70b81 215 SUPERFAMILY SSF53335 8 188 2.13E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS10540 b3892dc59d87a1549a434573631e60c4 337 Pfam PF13449 Esterase-like activity of phytase 62 313 5.5E-41 T 06-07-2017 IPR027372 Phytase-like domain CAK95_RS10540 b3892dc59d87a1549a434573631e60c4 337 PIRSF PIRSF031900 2 328 3.2E-108 T 06-07-2017 IPR014567 Uncharacterised conserved protein UCP031900 CAK95_RS10465 2d042f8979cbfd057de7286fc9f27b74 307 Pfam PF13616 PPIC-type PPIASE domain 143 239 1.0E-27 T 06-07-2017 CAK95_RS10465 2d042f8979cbfd057de7286fc9f27b74 307 Gene3D G3DSA:3.10.50.40 143 261 1.4E-45 T 06-07-2017 CAK95_RS10465 2d042f8979cbfd057de7286fc9f27b74 307 SUPERFAMILY SSF54534 144 237 4.06E-33 T 06-07-2017 CAK95_RS10465 2d042f8979cbfd057de7286fc9f27b74 307 SUPERFAMILY SSF109998 39 176 3.92E-13 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK95_RS15735 e31b129cb512d95c6a7ea1ec9e2c2dc4 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 3.4E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS15735 e31b129cb512d95c6a7ea1ec9e2c2dc4 326 SUPERFAMILY SSF53850 114 280 2.01E-7 T 06-07-2017 CAK95_RS15735 e31b129cb512d95c6a7ea1ec9e2c2dc4 326 PIRSF PIRSF017082 1 326 3.2E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS12740 0fbe22b6afab52bf4a020b110bc9312b 500 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 1.1E-136 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS12165 9f492e678636a2625c00a425f32471f2 222 Pfam PF07021 Methionine biosynthesis protein MetW 24 218 3.8E-89 T 06-07-2017 IPR010743 Methionine biosynthesis MetW CAK95_RS12165 9f492e678636a2625c00a425f32471f2 222 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 24 219 1.0E-78 T 06-07-2017 IPR010743 Methionine biosynthesis MetW CAK95_RS12165 9f492e678636a2625c00a425f32471f2 222 SUPERFAMILY SSF53335 34 210 2.54E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS12165 9f492e678636a2625c00a425f32471f2 222 Gene3D G3DSA:3.40.50.150 34 197 2.7E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03885 8a988c1f835508a4b1f5eff3da2be548 274 SUPERFAMILY SSF53335 43 173 5.43E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS03885 8a988c1f835508a4b1f5eff3da2be548 274 Pfam PF13847 Methyltransferase domain 66 197 1.8E-10 T 06-07-2017 IPR025714 Methyltransferase domain CAK95_RS03885 8a988c1f835508a4b1f5eff3da2be548 274 Gene3D G3DSA:3.40.50.150 48 164 5.8E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 Hamap MF_00416 Flagellar P-ring protein [flgI]. 13 375 37.0 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 198 216 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 115 132 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 262 274 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 48 63 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 93 112 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 172 190 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 132 150 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 33 48 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 PRINTS PR01010 Flagellar P-ring protein signature 68 83 4.3E-82 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS18170 59b0e171a88ec3cef40195f9e6b8c272 375 Pfam PF02119 Flagellar P-ring protein 33 374 3.5E-141 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAK95_RS23200 16d2b8e0e448a0e79ad979613516ac22 250 Pfam PF11860 Protein of unknown function (DUF3380) 27 191 4.8E-53 T 06-07-2017 IPR024408 Domain of unknown function DUF3380 CAK95_RS01520 1fbf1b4d301e6bf673fe86d0c1d4d98d 53 Pfam PF05532 CsbD-like 4 51 6.7E-11 T 06-07-2017 IPR008462 CsbD-like CAK95_RS01520 1fbf1b4d301e6bf673fe86d0c1d4d98d 53 SUPERFAMILY SSF69047 1 52 2.62E-10 T 06-07-2017 IPR008462 CsbD-like CAK95_RS01520 1fbf1b4d301e6bf673fe86d0c1d4d98d 53 Gene3D G3DSA:1.10.1470.10 1 52 3.1E-12 T 06-07-2017 IPR008462 CsbD-like CAK95_RS19960 06472a0b288dd0419c6e8782fd945e6f 119 Pfam PF01219 Prokaryotic diacylglycerol kinase 11 109 7.2E-27 T 06-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 CAK95_RS19960 06472a0b288dd0419c6e8782fd945e6f 119 Gene3D G3DSA:1.10.3830.10 2 114 9.6E-33 T 06-07-2017 CAK95_RS11105 68e9244c187d002638dc3cc71377b1f1 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 4.1E-23 T 06-07-2017 IPR021738 Protein of unknown function DUF3309 CAK95_RS07235 8884115b60e8674fe8f48ccce600dba7 88 Pfam PF06568 Domain of unknown function (DUF1127) 36 67 8.4E-7 T 06-07-2017 IPR009506 Protein of unknown function DUF1127 CAK95_RS26170 8fa32492d42cebb00e0e8c24b5c351fd 374 Gene3D G3DSA:3.20.20.210 7 372 4.1E-67 T 06-07-2017 CAK95_RS26170 8fa32492d42cebb00e0e8c24b5c351fd 374 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 166 345 2.5E-9 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK95_RS26170 8fa32492d42cebb00e0e8c24b5c351fd 374 SUPERFAMILY SSF51726 9 371 3.27E-48 T 06-07-2017 CAK95_RS19225 8526c12d9fcc8a1fde9d7fbae4e9b762 286 Pfam PF10670 Domain of unknown function (DUF4198) 21 263 2.5E-68 T 06-07-2017 IPR019613 Protein of unknown function DUF4198 CAK95_RS19225 8526c12d9fcc8a1fde9d7fbae4e9b762 286 Gene3D G3DSA:2.60.40.1120 210 277 8.3E-4 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 175 2.3E-5 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 148 159 2.3E-5 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 124 134 2.3E-5 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 Pfam PF00717 Peptidase S24-like 127 193 2.3E-16 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 Gene3D G3DSA:2.10.109.10 120 207 1.2E-21 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 SUPERFAMILY SSF51306 84 207 1.83E-24 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK95_RS05670 0cb7a90ce0d69b2a6673a14f76aaace4 209 Gene3D G3DSA:1.10.260.40 6 74 4.1E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK95_RS14775 74b439fedcb5c913b399e5264d867a4c 249 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 31 2.4E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK95_RS14775 74b439fedcb5c913b399e5264d867a4c 249 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 63 216 3.3E-37 T 06-07-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CAK95_RS01240 afc1f8d9c36eb7980bd5ff50d9ee884b 352 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 347 1.5E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01240 afc1f8d9c36eb7980bd5ff50d9ee884b 352 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 142 238 2.3E-19 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK95_RS01240 afc1f8d9c36eb7980bd5ff50d9ee884b 352 Gene3D G3DSA:1.10.3720.10 142 347 5.8E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS01240 afc1f8d9c36eb7980bd5ff50d9ee884b 352 SUPERFAMILY SSF161098 141 332 3.53E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS21875 944d617bd34f8272672ee46075c95fa8 111 Gene3D G3DSA:3.30.70.920 43 93 7.7E-4 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS21875 944d617bd34f8272672ee46075c95fa8 111 Pfam PF08734 GYD domain 4 92 3.9E-21 T 06-07-2017 IPR014845 Uncharacterised protein GYD CAK95_RS14835 4545ffc60919c5da2a71b579964f4f1c 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 307 2.8E-33 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS08890 9e1a8dff7b17de842ed0a8da1de9160d 482 Pfam PF03092 BT1 family 258 476 2.4E-12 T 06-07-2017 IPR004324 Folate-biopterin transporter GO:0006810|GO:0016021 CAK95_RS08890 9e1a8dff7b17de842ed0a8da1de9160d 482 Pfam PF03092 BT1 family 30 211 5.6E-13 T 06-07-2017 IPR004324 Folate-biopterin transporter GO:0006810|GO:0016021 CAK95_RS08890 9e1a8dff7b17de842ed0a8da1de9160d 482 SUPERFAMILY SSF103473 265 472 1.83E-6 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS08890 9e1a8dff7b17de842ed0a8da1de9160d 482 SUPERFAMILY SSF103473 21 228 1.83E-6 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 Gene3D G3DSA:3.40.190.10 60 137 4.0E-14 T 06-07-2017 CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 Gene3D G3DSA:3.40.190.10 314 378 4.0E-14 T 06-07-2017 CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 Gene3D G3DSA:3.40.190.10 184 313 4.3E-12 T 06-07-2017 CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 Pfam PF16868 NMT1-like family 184 378 4.2E-14 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 SUPERFAMILY SSF53850 188 378 6.51E-27 T 06-07-2017 CAK95_RS08725 a835c7807a0d4a0b34e4a4e7117d49f5 510 SUPERFAMILY SSF53850 59 146 6.51E-27 T 06-07-2017 CAK95_RS17600 0e5d540ce36a97751c68f9dd5decc398 326 Gene3D G3DSA:3.40.50.720 2 185 1.5E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17600 0e5d540ce36a97751c68f9dd5decc398 326 SUPERFAMILY SSF51735 2 325 4.32E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS17600 0e5d540ce36a97751c68f9dd5decc398 326 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 320 1.0E-122 T 06-07-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CAK95_RS17600 0e5d540ce36a97751c68f9dd5decc398 326 Gene3D G3DSA:3.90.25.10 186 301 3.1E-30 T 06-07-2017 CAK95_RS17600 0e5d540ce36a97751c68f9dd5decc398 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 247 3.1E-37 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS07410 76f838982426c05fd16499f32c0e3bc1 564 SUPERFAMILY SSF52091 461 563 1.02E-19 T 06-07-2017 IPR002645 STAS domain CAK95_RS07410 76f838982426c05fd16499f32c0e3bc1 564 Pfam PF00916 Sulfate permease family 37 400 6.1E-82 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK95_RS07410 76f838982426c05fd16499f32c0e3bc1 564 Pfam PF01740 STAS domain 461 544 8.3E-15 T 06-07-2017 IPR002645 STAS domain CAK95_RS07410 76f838982426c05fd16499f32c0e3bc1 564 Gene3D G3DSA:3.30.750.24 461 562 3.2E-19 T 06-07-2017 IPR002645 STAS domain CAK95_RS07535 859ae2075dd93b40369a055386b92ecc 271 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 27 266 1.9E-57 T 06-07-2017 CAK95_RS27270 526b025f6333e734326ba947c15d4ce5 382 Pfam PF13458 Periplasmic binding protein 16 355 3.4E-70 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS27270 526b025f6333e734326ba947c15d4ce5 382 Gene3D G3DSA:3.40.50.2300 15 208 5.9E-37 T 06-07-2017 CAK95_RS27270 526b025f6333e734326ba947c15d4ce5 382 SUPERFAMILY SSF53822 16 359 8.07E-82 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS08705 9a6b1a51143693a087281de84e3274d2 337 Gene3D G3DSA:3.40.50.1820 16 335 7.7E-93 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08705 9a6b1a51143693a087281de84e3274d2 337 SUPERFAMILY SSF53474 192 332 3.68E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08705 9a6b1a51143693a087281de84e3274d2 337 SUPERFAMILY SSF53474 65 139 3.68E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS25640 f685b204224778791831711ddd436156 154 Pfam PF07681 DoxX 6 103 4.2E-13 T 06-07-2017 IPR032808 DoxX family CAK95_RS06220 2c76170049a36ddbdc1ae8fcae372cf1 170 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 155 9.9E-22 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS25230 690942450d5963d854d29e6181696b2c 472 Gene3D G3DSA:1.25.40.10 294 437 3.4E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS25230 690942450d5963d854d29e6181696b2c 472 SUPERFAMILY SSF48452 296 429 2.95E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS25230 690942450d5963d854d29e6181696b2c 472 Pfam PF01435 Peptidase family M48 57 247 1.4E-28 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS25230 690942450d5963d854d29e6181696b2c 472 Gene3D G3DSA:3.30.2010.10 49 128 5.5E-16 T 06-07-2017 CAK95_RS25230 690942450d5963d854d29e6181696b2c 472 Pfam PF13432 Tetratricopeptide repeat 298 360 6.4E-7 T 06-07-2017 CAK95_RS11925 0fb60ffc111021686d95771031b16261 151 Pfam PF10116 Protein required for attachment to host cells 14 149 2.5E-42 T 06-07-2017 IPR019291 Host attachment protein CAK95_RS20705 b222c31ee929042d95238b684f1c0bc5 302 Pfam PF00561 alpha/beta hydrolase fold 31 276 2.0E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS20705 b222c31ee929042d95238b684f1c0bc5 302 SUPERFAMILY SSF53474 10 292 1.01E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20705 b222c31ee929042d95238b684f1c0bc5 302 Gene3D G3DSA:3.40.50.1820 10 292 8.5E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20535 693ccd702b068818b952594c79e5e36c 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 28 77 8.2E-14 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS20535 693ccd702b068818b952594c79e5e36c 149 SUPERFAMILY SSF69118 4 144 2.78E-45 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS20535 693ccd702b068818b952594c79e5e36c 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 93 1.3E-17 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK95_RS20535 693ccd702b068818b952594c79e5e36c 149 Gene3D G3DSA:1.20.1290.10 3 144 1.9E-49 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 15 139 2.3E-31 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 PRINTS PR00682 Isopenicillin N synthase signature 246 272 2.2E-11 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 PRINTS PR00682 Isopenicillin N synthase signature 38 55 2.2E-11 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 PRINTS PR00682 Isopenicillin N synthase signature 210 231 2.2E-11 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 Gene3D G3DSA:2.60.120.330 11 325 7.7E-104 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 187 284 3.0E-25 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK95_RS04795 0ce8dc83ababea7c834c894061c95f11 331 SUPERFAMILY SSF51197 13 325 5.49E-95 T 06-07-2017 CAK95_RS00585 1b1d0fb54504541dc62ab4bb7dc4ad59 87 Pfam PF09926 Uncharacterized small protein (DUF2158) 6 41 1.5E-9 T 06-07-2017 IPR019226 Protein of unknown function DUF2158 CAK95_RS01880 860bf0f4c22e9e6a9a79a0180ea36f25 514 Pfam PF14356 Domain of unknown function (DUF4403) 48 508 5.7E-88 T 06-07-2017 IPR025515 Protein of unknown function DUF4403 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Gene3D G3DSA:3.10.560.10 240 359 9.4E-27 T 06-07-2017 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Gene3D G3DSA:3.10.560.10 166 231 9.4E-18 T 06-07-2017 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Gene3D G3DSA:3.30.1950.10 86 165 1.9E-18 T 06-07-2017 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Pfam PF10531 SLBB domain 276 305 0.0034 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Pfam PF10531 SLBB domain 178 224 4.7E-6 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS26835 12c2d8c9af7d6f4c409a209f2183b049 390 Pfam PF02563 Polysaccharide biosynthesis/export protein 78 170 2.0E-16 T 06-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CAK95_RS28150 cbf6d45e427ffe8e7edf36846db809f1 349 Pfam PF01757 Acyltransferase family 15 314 1.1E-20 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK95_RS22560 822e6af5b8db71b4a6e719cf4ab3ab68 372 Gene3D G3DSA:3.40.50.2000 189 345 8.5E-13 T 06-07-2017 CAK95_RS22560 822e6af5b8db71b4a6e719cf4ab3ab68 372 SUPERFAMILY SSF53756 100 367 9.42E-51 T 06-07-2017 CAK95_RS22560 822e6af5b8db71b4a6e719cf4ab3ab68 372 Pfam PF00534 Glycosyl transferases group 1 200 344 5.7E-18 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 Gene3D G3DSA:1.10.10.60 267 317 6.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 SUPERFAMILY SSF46689 273 316 2.69E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 SMART SM00342 231 314 4.8E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 Pfam PF14525 AraC-binding-like domain 27 194 3.6E-20 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 283 298 7.6E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 298 314 7.6E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 SUPERFAMILY SSF51215 80 136 5.89E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 Pfam PF12833 Helix-turn-helix domain 237 315 1.9E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK95_RS27150 858abb0ee9752b9296d2fbe06844aa81 332 Gene3D G3DSA:1.10.10.60 217 266 6.0E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK95_RS24960 cbfb979dc8d0e3d5dd5a054f32eccecd 447 SUPERFAMILY SSF56935 55 389 2.52E-9 T 06-07-2017 CAK95_RS19510 853c9bb9e1e7f1d0418bd7cbd6c16930 49 Gene3D G3DSA:1.10.1220.10 4 37 7.1E-6 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK95_RS19510 853c9bb9e1e7f1d0418bd7cbd6c16930 49 SUPERFAMILY SSF47598 4 39 1.67E-6 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK95_RS16080 2762356dd2ba37f1ac7af4eaa625db39 366 Gene3D G3DSA:2.120.10.30 13 356 5.8E-60 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK95_RS16080 2762356dd2ba37f1ac7af4eaa625db39 366 SUPERFAMILY SSF50952 10 355 2.35E-31 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK95_RS16080 2762356dd2ba37f1ac7af4eaa625db39 366 Pfam PF07995 Glucose / Sorbosone dehydrogenase 130 274 7.9E-12 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAK95_RS04360 0808ad6788b592efd04785d59a8d0c17 59 Pfam PF04325 Protein of unknown function (DUF465) 9 52 2.8E-15 T 06-07-2017 IPR007420 Protein of unknown function DUF465 CAK95_RS00285 e7a30813fcf5b03eb997d9dce6476c5a 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 275 7.2E-33 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS01085 ddf264a2c2f52f2d18809667c4610171 330 Pfam PF02073 Thermophilic metalloprotease (M29) 127 293 4.2E-6 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 CAK95_RS01085 ddf264a2c2f52f2d18809667c4610171 330 SUPERFAMILY SSF144052 99 328 4.05E-24 T 06-07-2017 CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 SUPERFAMILY SSF51430 9 270 1.17E-83 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 Pfam PF00248 Aldo/keto reductase family 19 267 3.0E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 PRINTS PR00069 Aldo-keto reductase signature 98 116 3.7E-17 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 PRINTS PR00069 Aldo-keto reductase signature 202 226 3.7E-17 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 PRINTS PR00069 Aldo-keto reductase signature 42 66 3.7E-17 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 PRINTS PR00069 Aldo-keto reductase signature 128 145 3.7E-17 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK95_RS17225 3b9d125fa1db1318173c7a99bd7d5219 280 Gene3D G3DSA:3.20.20.100 9 270 4.7E-82 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK95_RS19115 d8cb3723cc4d075b0b3a1d4fde84720a 191 SUPERFAMILY SSF53474 8 138 1.04E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS19115 d8cb3723cc4d075b0b3a1d4fde84720a 191 Gene3D G3DSA:3.40.50.1820 8 111 2.1E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS23715 48845a4507275446129d6a39dae0c157 289 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 4 247 2.6E-71 T 06-07-2017 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CAK95_RS23715 48845a4507275446129d6a39dae0c157 289 SUPERFAMILY SSF53850 45 239 7.43E-40 T 06-07-2017 CAK95_RS23715 48845a4507275446129d6a39dae0c157 289 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 34 270 1.2E-68 T 06-07-2017 CAK95_RS23715 48845a4507275446129d6a39dae0c157 289 Gene3D G3DSA:3.40.190.10 119 235 1.8E-15 T 06-07-2017 CAK95_RS03010 932518a033e34b8962f4359edc8526b7 281 Gene3D G3DSA:3.40.50.300 21 242 3.6E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS03010 932518a033e34b8962f4359edc8526b7 281 Pfam PF13479 AAA domain 18 255 9.7E-43 T 06-07-2017 CAK95_RS03010 932518a033e34b8962f4359edc8526b7 281 SUPERFAMILY SSF52540 20 219 3.6E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS28415 556496a1cf55b76051e0cbc4f572cd91 453 SUPERFAMILY SSF56112 86 149 8.75E-19 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS28415 556496a1cf55b76051e0cbc4f572cd91 453 SUPERFAMILY SSF56112 181 306 8.75E-19 T 06-07-2017 IPR011009 Protein kinase-like domain CAK95_RS28415 556496a1cf55b76051e0cbc4f572cd91 453 Pfam PF03109 ABC1 family 104 218 1.4E-29 T 06-07-2017 IPR004147 UbiB domain CAK95_RS06640 0dd201fb5510f38408c20629ca2e10ec 53 Pfam PF04964 Flp/Fap pilin component 7 50 1.1E-18 T 06-07-2017 IPR007047 Flp/Fap pilin component CAK95_RS14780 ab3e5242233be7e4a7f163a2ac5e21e7 283 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 2 279 4.7E-96 T 06-07-2017 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK95_RS14780 ab3e5242233be7e4a7f163a2ac5e21e7 283 Gene3D G3DSA:3.40.1190.20 2 277 1.7E-81 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS14780 ab3e5242233be7e4a7f163a2ac5e21e7 283 SUPERFAMILY SSF53613 3 270 1.23E-62 T 06-07-2017 IPR029056 Ribokinase-like CAK95_RS14780 ab3e5242233be7e4a7f163a2ac5e21e7 283 Pfam PF08543 Phosphomethylpyrimidine kinase 79 250 2.3E-12 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAK95_RS18350 45c554d27125e5017bbe4ab91407cc67 70 SUPERFAMILY SSF49503 1 48 3.66E-10 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS18350 45c554d27125e5017bbe4ab91407cc67 70 Gene3D G3DSA:2.60.40.420 4 38 4.3E-8 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS20645 724988a6caf7de6e9b024319a81694cb 148 Pfam PF08308 PEGA domain 27 77 1.4E-4 T 06-07-2017 IPR013229 PEGA CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 Pfam PF05199 GMC oxidoreductase 450 507 1.2E-17 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 SUPERFAMILY SSF51905 1 310 6.57E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 SUPERFAMILY SSF51905 456 516 6.57E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 Gene3D G3DSA:3.50.50.60 2 127 4.6E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 Gene3D G3DSA:3.50.50.60 199 305 4.6E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 Gene3D G3DSA:3.50.50.60 433 515 4.6E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS00890 0f040bc7fd066a5ef6da116718b937e3 517 Pfam PF00732 GMC oxidoreductase 5 299 2.9E-9 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK95_RS27215 15b015419b2b3762770e962f7d8986b5 134 Pfam PF01042 Endoribonuclease L-PSP 21 129 6.5E-25 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS27215 15b015419b2b3762770e962f7d8986b5 134 SUPERFAMILY SSF55298 14 131 1.01E-30 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS27215 15b015419b2b3762770e962f7d8986b5 134 Gene3D G3DSA:3.30.1330.40 15 131 1.5E-34 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS07650 75b83e5a69dc259f1520a94ed82ed703 110 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 80 23.855 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07650 75b83e5a69dc259f1520a94ed82ed703 110 SUPERFAMILY SSF54565 3 87 1.31E-30 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07650 75b83e5a69dc259f1520a94ed82ed703 110 Gene3D G3DSA:3.30.1320.10 3 86 1.3E-32 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07650 75b83e5a69dc259f1520a94ed82ed703 110 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 82 2.3E-30 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS07650 75b83e5a69dc259f1520a94ed82ed703 110 Pfam PF00886 Ribosomal protein S16 9 70 5.6E-27 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK95_RS09745 eb0d776ad178edb39ff1d17707c24b0a 124 SUPERFAMILY SSF54593 11 114 1.38E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS09745 eb0d776ad178edb39ff1d17707c24b0a 124 Gene3D G3DSA:3.10.180.10 9 114 8.0E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS26155 52370ef1b11b265ae5d574b408f6af6f 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 156 3.2E-38 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK95_RS26155 52370ef1b11b265ae5d574b408f6af6f 160 SUPERFAMILY SSF55961 9 158 1.43E-49 T 06-07-2017 CAK95_RS26155 52370ef1b11b265ae5d574b408f6af6f 160 Gene3D G3DSA:3.30.530.20 6 158 5.3E-53 T 06-07-2017 IPR023393 START-like domain CAK95_RS25215 a790468087f6347708b8d11a61bb70d7 270 Pfam PF14067 LssY C-terminus 44 225 1.1E-68 T 06-07-2017 IPR025902 LssY-like C-terminal domain CAK95_RS00670 e44c50e900690176641cb8a409bfc74b 69 Pfam PF07043 Protein of unknown function (DUF1328) 6 40 1.3E-5 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAK95_RS00670 e44c50e900690176641cb8a409bfc74b 69 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 52 14.043 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAK95_RS11170 3fea4b18f3758339cf65c5f2fbc92f4f 448 PIRSF PIRSF005353 9 446 1.3E-174 T 06-07-2017 IPR026033 Purine permease PbuG-like CAK95_RS11170 3fea4b18f3758339cf65c5f2fbc92f4f 448 Pfam PF00860 Permease family 34 407 9.7E-53 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK95_RS11955 c2222cea1afb8a31ed457c8b6f7925a8 123 SUPERFAMILY SSF54427 5 109 9.58E-12 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS11955 c2222cea1afb8a31ed457c8b6f7925a8 123 Gene3D G3DSA:3.10.450.50 2 110 1.6E-9 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS00120 35aa8776bcee26606ac8732478228661 326 Gene3D G3DSA:3.20.20.140 262 324 6.4E-5 T 06-07-2017 CAK95_RS00120 35aa8776bcee26606ac8732478228661 326 SUPERFAMILY SSF51556 171 320 5.61E-14 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS00120 35aa8776bcee26606ac8732478228661 326 SUPERFAMILY SSF51556 42 142 5.61E-14 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS18635 4e727768bb4245d4ed1e760d85feb3b6 193 Pfam PF00565 Staphylococcal nuclease homologue 39 142 3.6E-14 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS18635 4e727768bb4245d4ed1e760d85feb3b6 193 Gene3D G3DSA:2.40.50.90 23 143 4.4E-20 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS18635 4e727768bb4245d4ed1e760d85feb3b6 193 SMART SM00318 17 143 4.5E-15 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS18635 4e727768bb4245d4ed1e760d85feb3b6 193 SUPERFAMILY SSF50199 24 147 6.93E-29 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 Gene3D G3DSA:2.60.120.580 213 281 3.7E-66 T 06-07-2017 CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 Gene3D G3DSA:2.60.120.580 6 94 3.7E-66 T 06-07-2017 CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 Gene3D G3DSA:2.60.120.580 147 164 3.7E-66 T 06-07-2017 CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 Pfam PF03069 Acetamidase/Formamidase family 7 384 1.2E-173 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 SUPERFAMILY SSF141130 213 383 7.19E-79 T 06-07-2017 CAK95_RS28490 6ebf3997c9f7638876a0aa505b60d236 409 SUPERFAMILY SSF141130 16 164 7.19E-79 T 06-07-2017 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 Pfam PF01266 FAD dependent oxidoreductase 12 324 1.9E-36 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 SUPERFAMILY SSF54373 201 289 1.7E-17 T 06-07-2017 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 Gene3D G3DSA:3.30.9.10 192 289 4.1E-18 T 06-07-2017 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 SUPERFAMILY SSF51971 276 330 8.47E-26 T 06-07-2017 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 SUPERFAMILY SSF51971 7 214 8.47E-26 T 06-07-2017 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 Gene3D G3DSA:3.50.50.60 134 191 9.0E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 Gene3D G3DSA:3.50.50.60 291 329 9.0E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS01900 6861eee8b6305c5191773f3bf9099f5f 341 Gene3D G3DSA:3.50.50.60 9 84 9.0E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK95_RS17065 4a8ddeacb7239552b8902db85b6684b1 264 Pfam PF04199 Putative cyclase 6 158 5.1E-31 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAK95_RS17065 4a8ddeacb7239552b8902db85b6684b1 264 Gene3D G3DSA:3.50.30.50 3 159 1.2E-64 T 06-07-2017 CAK95_RS17065 4a8ddeacb7239552b8902db85b6684b1 264 Gene3D G3DSA:3.50.30.50 194 250 1.2E-64 T 06-07-2017 CAK95_RS17065 4a8ddeacb7239552b8902db85b6684b1 264 SUPERFAMILY SSF102198 2 159 5.23E-51 T 06-07-2017 CAK95_RS17065 4a8ddeacb7239552b8902db85b6684b1 264 SUPERFAMILY SSF102198 194 249 5.23E-51 T 06-07-2017 CAK95_RS07100 1eb9dd9454980b1816ffc164616ca7dc 221 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 206 7.0E-70 T 06-07-2017 IPR022301 Integral membrane protein YjbE CAK95_RS07100 1eb9dd9454980b1816ffc164616ca7dc 221 Pfam PF03741 Integral membrane protein TerC family 14 205 8.9E-45 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK95_RS21020 18f109f8e0abce120a88d2715f29e4d0 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 457 6.5E-78 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK95_RS21020 18f109f8e0abce120a88d2715f29e4d0 538 Gene3D G3DSA:3.90.76.10 46 225 1.7E-31 T 06-07-2017 CAK95_RS21020 18f109f8e0abce120a88d2715f29e4d0 538 Gene3D G3DSA:3.10.105.10 298 508 1.2E-45 T 06-07-2017 CAK95_RS21020 18f109f8e0abce120a88d2715f29e4d0 538 SUPERFAMILY SSF53850 34 534 3.62E-107 T 06-07-2017 CAK95_RS21020 18f109f8e0abce120a88d2715f29e4d0 538 PIRSF PIRSF002741 73 524 3.4E-69 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK95_RS07935 00c246ea9d688c1a2bb2c6e88d6186ea 478 SUPERFAMILY SSF51338 376 444 2.94E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK95_RS07935 00c246ea9d688c1a2bb2c6e88d6186ea 478 Pfam PF01979 Amidohydrolase family 45 426 1.7E-28 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS07935 00c246ea9d688c1a2bb2c6e88d6186ea 478 Gene3D G3DSA:3.20.20.140 49 391 2.8E-58 T 06-07-2017 CAK95_RS07935 00c246ea9d688c1a2bb2c6e88d6186ea 478 SUPERFAMILY SSF51556 47 364 1.55E-55 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS01395 a1ea08f10488601a55d3d1bae6680a1a 650 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 616 3.6E-172 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein CAK95_RS01395 a1ea08f10488601a55d3d1bae6680a1a 650 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 122 556 3.1E-95 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS11810 4a7ef19a2fe967c95ee25ca34943fe5b 706 Pfam PF01968 Hydantoinase/oxoprolinase 232 508 1.0E-62 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS11810 4a7ef19a2fe967c95ee25ca34943fe5b 706 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 26 209 5.2E-39 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS19720 1c7098d81f0e526e8405d0a891fdbd56 193 Pfam PF13649 Methyltransferase domain 22 122 1.1E-23 T 06-07-2017 CAK95_RS19720 1c7098d81f0e526e8405d0a891fdbd56 193 SUPERFAMILY SSF53335 5 177 2.26E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS19720 1c7098d81f0e526e8405d0a891fdbd56 193 Gene3D G3DSA:3.40.50.150 4 175 3.5E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS02830 6a7dce9f5af152934b89a98151ba9155 166 Gene3D G3DSA:3.40.630.30 1 128 3.2E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS02830 6a7dce9f5af152934b89a98151ba9155 166 Pfam PF13527 Acetyltransferase (GNAT) domain 5 127 1.8E-11 T 06-07-2017 CAK95_RS02830 6a7dce9f5af152934b89a98151ba9155 166 SUPERFAMILY SSF55729 1 131 2.02E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS05125 cda438224f3235a4efa8b9b111a6b845 218 SUPERFAMILY SSF53474 43 132 2.05E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS05125 cda438224f3235a4efa8b9b111a6b845 218 Gene3D G3DSA:3.40.50.1820 38 118 8.7E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS17500 96bb7f7b4539b52592c166fd00ae6b6e 380 SUPERFAMILY SSF53850 155 234 7.6E-5 T 06-07-2017 CAK95_RS17500 96bb7f7b4539b52592c166fd00ae6b6e 380 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 73 334 2.4E-23 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS19340 50c9483af8d13a2d5969f66b6131119f 158 Pfam PF01618 MotA/TolQ/ExbB proton channel family 72 137 4.6E-6 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAK95_RS11235 f3c8bfed9ba19856d6cebfcc65662820 302 Pfam PF04228 Putative neutral zinc metallopeptidase 1 297 8.5E-110 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CAK95_RS01210 e12a3a8c968a91a674eb0fcd7627558c 293 Gene3D G3DSA:3.90.850.10 62 285 5.8E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS01210 e12a3a8c968a91a674eb0fcd7627558c 293 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 282 6.9E-61 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS01210 e12a3a8c968a91a674eb0fcd7627558c 293 SUPERFAMILY SSF56529 64 283 3.27E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK95_RS07635 c521b41fb3ee63fcb5a6aeece529155a 265 Gene3D G3DSA:3.40.50.360 1 234 7.1E-73 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS07635 c521b41fb3ee63fcb5a6aeece529155a 265 SUPERFAMILY SSF52218 1 246 5.83E-72 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK95_RS07635 c521b41fb3ee63fcb5a6aeece529155a 265 Pfam PF02525 Flavodoxin-like fold 1 216 2.1E-56 T 06-07-2017 IPR003680 Flavodoxin-like fold CAK95_RS23360 f704ec895f8cb4437aa16963befa224b 174 Pfam PF04586 Caudovirus prohead serine protease 1 135 1.9E-15 T 06-07-2017 IPR006433 Prohead protease CAK95_RS04135 dad3cffb8ad467978d9575a7687535a1 98 Pfam PF13747 Domain of unknown function (DUF4164) 10 94 3.3E-24 T 06-07-2017 IPR025310 Protein of unknown function DUF4164 CAK95_RS03410 0941d8d63650095e29de9e5b33b7e5e6 146 Pfam PF11149 Protein of unknown function (DUF2924) 7 140 2.1E-52 T 06-07-2017 IPR021322 Protein of unknown function DUF2924 CAK95_RS04525 7d681768a59af2639f5c68308a1a2c01 198 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 34 144 6.3E-24 T 06-07-2017 IPR019223 Domain of unknown function DUF2147 CAK95_RS00240 7175b62aa08b442cdb7370397cda8795 145 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 1 132 1.6E-26 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS05255 844d697532e6acd18fbfd85f2989a613 240 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 95 214 4.3E-7 T 06-07-2017 IPR010664 Lipopolysaccharide assembly, LptC-related CAK95_RS08925 5aaab75d8d66a32384cb1d218a72ffa9 203 SUPERFAMILY SSF53335 21 185 7.41E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS08925 5aaab75d8d66a32384cb1d218a72ffa9 203 Gene3D G3DSA:3.40.50.150 42 143 2.5E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01670 2a253d970ee8b482de594d57e008909a 135 Pfam PF07172 Glycine rich protein family 11 95 4.2E-7 T 06-07-2017 IPR010800 Glycine rich protein CAK95_RS23510 0521b84ffd09f4320ad0ac5647d21d88 217 Pfam PF04191 Phospholipid methyltransferase 81 150 3.9E-10 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK95_RS20120 aa9c6291ca63d16e9cdbf72bc458bb4b 732 SUPERFAMILY SSF101898 365 390 2.88E-7 T 06-07-2017 CAK95_RS20120 aa9c6291ca63d16e9cdbf72bc458bb4b 732 SUPERFAMILY SSF101898 417 478 2.88E-7 T 06-07-2017 CAK95_RS20120 aa9c6291ca63d16e9cdbf72bc458bb4b 732 SUPERFAMILY SSF101898 509 590 2.88E-7 T 06-07-2017 CAK95_RS17665 c4d220014db55c74688821d582e7cedf 333 Gene3D G3DSA:3.20.20.370 217 276 2.6E-17 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS17665 c4d220014db55c74688821d582e7cedf 333 Gene3D G3DSA:3.20.20.370 70 119 2.6E-17 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS17665 c4d220014db55c74688821d582e7cedf 333 Pfam PF01522 Polysaccharide deacetylase 75 294 2.8E-18 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS17665 c4d220014db55c74688821d582e7cedf 333 SUPERFAMILY SSF88713 41 119 1.58E-23 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS17665 c4d220014db55c74688821d582e7cedf 333 SUPERFAMILY SSF88713 217 295 1.58E-23 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS00985 60b58bc16e67fb935c7ca79895e7882d 275 SUPERFAMILY SSF161098 6 275 8.37E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00985 60b58bc16e67fb935c7ca79895e7882d 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 264 1.0E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS00985 60b58bc16e67fb935c7ca79895e7882d 275 Gene3D G3DSA:1.10.3720.10 5 262 9.9E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS23290 b0d8723e045e58d1237c9db09ff9b6bc 390 Pfam PF06078 Bacterial protein of unknown function (DUF937) 19 150 7.2E-15 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK95_RS04080 9eff7216da778a3b03e7026fc6dc111d 260 Pfam PF01925 Sulfite exporter TauE/SafE 24 249 1.3E-22 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS02275 2a4666a44433b56fcbf33f7fa28d63b1 143 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 2 132 6.9E-19 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS09130 98724545d9911ed8afb3018081a92d5c 240 Pfam PF00156 Phosphoribosyl transferase domain 71 198 8.3E-19 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK95_RS09130 98724545d9911ed8afb3018081a92d5c 240 SUPERFAMILY SSF53271 70 194 8.66E-23 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS09130 98724545d9911ed8afb3018081a92d5c 240 Gene3D G3DSA:3.40.50.2020 69 201 8.4E-27 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK95_RS01290 b22c25a9599772313137de4050ea2d9e 255 Gene3D G3DSA:3.90.550.10 14 184 2.1E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS01290 b22c25a9599772313137de4050ea2d9e 255 Pfam PF00535 Glycosyl transferase family 2 16 177 1.7E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK95_RS01290 b22c25a9599772313137de4050ea2d9e 255 SUPERFAMILY SSF53448 14 240 3.8E-36 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS01455 ee207a59ae0f5e0c342d88062c73a310 619 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 21 149 9.4E-12 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS01455 ee207a59ae0f5e0c342d88062c73a310 619 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 198 609 5.2E-83 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS19870 d98ac67fcca6397575dcd068079520cf 194 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 1.0E-20 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS06680 76bb02cbaf94a7a1aaa34de06892d07e 324 Pfam PF00482 Type II secretion system (T2SS), protein F 185 313 8.4E-21 T 06-07-2017 IPR018076 Type II secretion system F domain CAK95_RS21995 983ad6e7c0599e93e4f858a1172ba66f 417 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 23 412 7.3E-160 T 06-07-2017 IPR007434 Peptidogalycan biosysnthesis/recognition CAK95_RS21995 983ad6e7c0599e93e4f858a1172ba66f 417 SUPERFAMILY SSF55729 214 388 2.7E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS21995 983ad6e7c0599e93e4f858a1172ba66f 417 Gene3D G3DSA:3.40.630.30 214 361 1.1E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS14850 19bb43e697a695faa81592f3eada774e 255 SUPERFAMILY SSF52540 16 250 3.91E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14850 19bb43e697a695faa81592f3eada774e 255 Gene3D G3DSA:3.40.50.300 15 247 5.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS14850 19bb43e697a695faa81592f3eada774e 255 Pfam PF00005 ABC transporter 34 178 1.0E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK95_RS14850 19bb43e697a695faa81592f3eada774e 255 SMART SM00382 42 228 9.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK95_RS16715 7cda1424d83b959ec5928abdbfa47b56 51 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 4 51 3.6E-22 T 06-07-2017 IPR008621 Cbb3-type cytochrome oxidase component CAK95_RS02340 b734140d6576829e93bdaedb5533741d 245 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 9 244 4.3E-53 T 06-07-2017 IPR014147 Type IV conjugative transfer protein TrbJ CAK95_RS01955 ce66d71dfc3d075391842bb407d96f73 205 SUPERFAMILY SSF53335 5 185 2.61E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS01955 ce66d71dfc3d075391842bb407d96f73 205 Pfam PF13649 Methyltransferase domain 42 135 1.3E-15 T 06-07-2017 CAK95_RS01955 ce66d71dfc3d075391842bb407d96f73 205 Gene3D G3DSA:3.40.50.150 8 184 7.1E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS15085 e866d378e114b83d2960d23e5a48de6d 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 272 5.0E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS16605 f036a69679deca094a18a6d11c853ffc 367 Pfam PF02653 Branched-chain amino acid transport system / permease component 79 355 7.0E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS22495 f6d5a125d1bee97596bb339b1bb6b6a6 153 Pfam PF04355 SmpA / OmlA family 40 113 1.2E-17 T 06-07-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 CAK95_RS28190 30fe21b05512c33e90ddd939a38a4e33 66 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 47 2.1E-14 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB CAK95_RS08475 b28ad495ee37378d1cb48e6a61c5ca5c 235 Gene3D G3DSA:3.40.50.1820 3 231 5.7E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS08475 b28ad495ee37378d1cb48e6a61c5ca5c 235 Pfam PF12697 Alpha/beta hydrolase family 5 228 4.8E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK95_RS08475 b28ad495ee37378d1cb48e6a61c5ca5c 235 SUPERFAMILY SSF53474 5 230 6.95E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS22055 ec858792fc8bfdeb0ca01804ae357182 148 Pfam PF06170 Protein of unknown function (DUF983) 36 120 1.6E-34 T 06-07-2017 IPR009325 Protein of unknown function DUF983 CAK95_RS22915 c413deded0e07276e5ec795fe4d9d553 87 Pfam PF07330 Protein of unknown function (DUF1467) 3 80 2.1E-30 T 06-07-2017 IPR009935 Protein of unknown function DUF1467 CAK95_RS09960 b2723438e639cccc1b0609ab7187a1d4 126 Pfam PF09722 Protein of unknown function (DUF2384) 76 123 5.7E-12 T 06-07-2017 IPR024467 Domain of unknown function DUF2384 CAK95_RS08130 3df2ce3ad646ab2e603633e596279f6d 247 Pfam PF01925 Sulfite exporter TauE/SafE 13 242 3.8E-28 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS22435 6d67e36ceecdfa9cfe45e9f4324a6b4d 162 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 84.771 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAK95_RS22435 6d67e36ceecdfa9cfe45e9f4324a6b4d 162 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.7E-50 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAK95_RS22435 6d67e36ceecdfa9cfe45e9f4324a6b4d 162 Pfam PF03477 ATP cone domain 50 136 1.9E-20 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CAK95_RS04450 8c30396e90ecfdf0880f740682bdf07e 425 Pfam PF13458 Periplasmic binding protein 39 376 3.3E-74 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS04450 8c30396e90ecfdf0880f740682bdf07e 425 Gene3D G3DSA:3.40.50.2300 165 315 1.3E-26 T 06-07-2017 CAK95_RS04450 8c30396e90ecfdf0880f740682bdf07e 425 SUPERFAMILY SSF53822 39 403 1.39E-83 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS04450 8c30396e90ecfdf0880f740682bdf07e 425 Gene3D G3DSA:3.40.50.2300 35 162 1.9E-38 T 06-07-2017 CAK95_RS04450 8c30396e90ecfdf0880f740682bdf07e 425 Gene3D G3DSA:3.40.50.2300 316 370 1.9E-38 T 06-07-2017 CAK95_RS16680 b874fecf5ceff6ae8d0c2dd630119365 62 Pfam PF11450 Protein of unknwon function (DUF3008) 3 58 2.8E-30 T 06-07-2017 IPR021553 Protein of unknwon function DUF3008 CAK95_RS24145 9103782d5826287200d4a87ca572abe4 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 313 7.1E-47 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS08620 59cc85162c321cd3430017683e4ff6ae 114 SUPERFAMILY SSF141488 39 113 4.97E-16 T 06-07-2017 IPR018660 C-type lysozyme, inhibitor CAK95_RS08620 59cc85162c321cd3430017683e4ff6ae 114 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 44 109 4.1E-14 T 06-07-2017 IPR018660 C-type lysozyme, inhibitor CAK95_RS26110 eca17362f002dfdbe797bab97885bd02 194 Pfam PF07298 NnrU protein 6 190 9.1E-56 T 06-07-2017 IPR009915 NnrU domain CAK95_RS01810 d7eef03d42460c2cc71c91cf4e0ea07f 181 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 155 1.3E-20 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS19920 e2bae1f5d60db295fa2d8ec2e6daa83e 189 Pfam PF08308 PEGA domain 35 83 5.1E-6 T 06-07-2017 IPR013229 PEGA CAK95_RS12660 67ea1012c186e09da5b8bf093c1e1c4f 125 Pfam PF09361 Phasin protein 30 123 1.7E-15 T 06-07-2017 IPR018968 Phasin CAK95_RS18270 e6a638da7f5a706baff5038c0a9d646a 358 Pfam PF04347 Flagellar biosynthesis protein, FliO 31 98 9.5E-7 T 06-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CAK95_RS15800 bbaa984214cdfbeab1371e77e08fadd9 374 Pfam PF01435 Peptidase family M48 182 347 5.1E-24 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS15800 bbaa984214cdfbeab1371e77e08fadd9 374 Gene3D G3DSA:3.30.2010.10 172 254 1.4E-18 T 06-07-2017 CAK95_RS19435 2a6e2b2732c559f749e31915e39fa20f 320 Pfam PF08401 Domain of unknown function (DUF1738) 17 139 4.2E-40 T 06-07-2017 IPR013610 Domain of unknown function DUF1738 CAK95_RS19435 2a6e2b2732c559f749e31915e39fa20f 320 PIRSF PIRSF037112 3 311 9.0E-110 T 06-07-2017 IPR017113 Antirestriction, ArdC CAK95_RS24060 e2120a54daa4bc0f4e5555b4f6dce796 234 Pfam PF13460 NAD(P)H-binding 7 171 3.2E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24060 e2120a54daa4bc0f4e5555b4f6dce796 234 Gene3D G3DSA:3.40.50.720 1 213 2.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS24060 e2120a54daa4bc0f4e5555b4f6dce796 234 SUPERFAMILY SSF51735 1 228 1.75E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS20865 53c0063df98562c3ab65740ad92491c4 390 Gene3D G3DSA:1.10.530.10 19 75 4.1E-7 T 06-07-2017 CAK95_RS20865 53c0063df98562c3ab65740ad92491c4 390 Pfam PF01464 Transglycosylase SLT domain 21 69 7.0E-5 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAK95_RS20865 53c0063df98562c3ab65740ad92491c4 390 SUPERFAMILY SSF53955 20 91 3.94E-8 T 06-07-2017 IPR023346 Lysozyme-like domain CAK95_RS03565 6dad9656eef9a74766a938d1a115a931 208 Pfam PF07813 LTXXQ motif family protein 95 186 2.7E-9 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS12125 ea9ea4cf4d28414fbfb964c172484aa3 218 Gene3D G3DSA:3.40.50.620 59 169 4.7E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK95_RS12125 ea9ea4cf4d28414fbfb964c172484aa3 218 Pfam PF02698 DUF218 domain 62 199 7.2E-16 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAK95_RS12125 ea9ea4cf4d28414fbfb964c172484aa3 218 ProDom PD207074 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED RC1356 RP875 58 180 6.0E-5 T 06-07-2017 CAK95_RS09280 82a82c1f6fd9ac2529ad99bf00dd1385 282 Gene3D G3DSA:3.60.15.10 61 252 2.2E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09280 82a82c1f6fd9ac2529ad99bf00dd1385 282 SUPERFAMILY SSF56281 68 251 4.15E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK95_RS09280 82a82c1f6fd9ac2529ad99bf00dd1385 282 Pfam PF13483 Beta-lactamase superfamily domain 69 235 3.3E-45 T 06-07-2017 CAK95_RS10450 babdaea1aeb6030b1eb1f115ac0e5ff4 60 Pfam PF04964 Flp/Fap pilin component 13 58 3.5E-16 T 06-07-2017 IPR007047 Flp/Fap pilin component CAK95_RS20060 b21e136d8de3c086b85363ac7f9c7255 124 Gene3D G3DSA:3.10.180.10 1 121 9.0E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20060 b21e136d8de3c086b85363ac7f9c7255 124 SUPERFAMILY SSF54593 2 123 1.48E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK95_RS20060 b21e136d8de3c086b85363ac7f9c7255 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 118 1.8E-12 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK95_RS11520 87b7e5502dbfb4ef183d66bde8c98f00 159 Gene3D G3DSA:2.60.120.10 22 149 3.1E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS11520 87b7e5502dbfb4ef183d66bde8c98f00 159 SUPERFAMILY SSF51182 94 154 7.79E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS11520 87b7e5502dbfb4ef183d66bde8c98f00 159 SUPERFAMILY SSF51182 32 67 7.79E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS23390 b6184ef18c23dc3c0165e126a9153b60 466 SUPERFAMILY SSF52540 134 335 2.39E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS23390 b6184ef18c23dc3c0165e126a9153b60 466 Pfam PF13481 AAA domain 126 299 2.7E-27 T 06-07-2017 CAK95_RS23390 b6184ef18c23dc3c0165e126a9153b60 466 Gene3D G3DSA:3.40.50.300 128 361 8.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK95_RS26885 e1b03e1bb2d484a89a71a540a4c80a02 270 Pfam PF01061 ABC-2 type transporter 24 232 1.4E-11 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK95_RS06715 b840bf4d0ef116e985a5f3aa75eb771d 371 SUPERFAMILY SSF161098 137 348 2.62E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06715 b840bf4d0ef116e985a5f3aa75eb771d 371 Gene3D G3DSA:1.10.3720.10 136 355 2.1E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS06715 b840bf4d0ef116e985a5f3aa75eb771d 371 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 157 364 3.2E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03615 6c82f2477adc2988b88d1b22521690d4 276 Pfam PF14067 LssY C-terminus 68 265 1.7E-61 T 06-07-2017 IPR025902 LssY-like C-terminal domain CAK95_RS21620 db85d5f48d0275e9f2147ad740e1553a 156 Pfam PF07681 DoxX 28 102 3.8E-14 T 06-07-2017 IPR032808 DoxX family CAK95_RS13390 2f8a295dcbe047d05a92fded1a92c9fd 293 SUPERFAMILY SSF53474 29 251 9.43E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS13390 2f8a295dcbe047d05a92fded1a92c9fd 293 Pfam PF01738 Dienelactone hydrolase family 47 292 3.1E-15 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK95_RS13390 2f8a295dcbe047d05a92fded1a92c9fd 293 Gene3D G3DSA:3.40.50.1820 35 292 4.4E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS20185 f0884e9bc7deded5f82457a34e52463f 194 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 89 172 7.2E-16 T 06-07-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CAK95_RS27460 102dc994f00fe7a2c7571bfb998fd1c5 476 Pfam PF04932 O-Antigen ligase 264 405 2.6E-18 T 06-07-2017 IPR007016 O-antigen ligase-related CAK95_RS00020 6ebb3b341fa8d933c5b7ec389f8cea8f 279 Pfam PF13649 Methyltransferase domain 58 150 7.3E-23 T 06-07-2017 CAK95_RS00020 6ebb3b341fa8d933c5b7ec389f8cea8f 279 SUPERFAMILY SSF53335 33 238 2.46E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS00020 6ebb3b341fa8d933c5b7ec389f8cea8f 279 Gene3D G3DSA:3.40.50.150 42 235 6.5E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK95_RS12510 565c939fb36d4df544308a1c8544e8e1 237 Pfam PF00857 Isochorismatase family 37 222 1.2E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12510 565c939fb36d4df544308a1c8544e8e1 237 SUPERFAMILY SSF52499 30 228 3.4E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS12510 565c939fb36d4df544308a1c8544e8e1 237 Gene3D G3DSA:3.40.50.850 31 230 1.1E-52 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS09420 83df007cc7416337894c9f9a0cb0a667 177 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 14 160 1.7E-13 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS02190 8a517d16516fe288938433228db3bb8a 343 Gene3D G3DSA:3.40.190.10 137 251 1.7E-7 T 06-07-2017 CAK95_RS02190 8a517d16516fe288938433228db3bb8a 343 SUPERFAMILY SSF53850 45 292 5.97E-27 T 06-07-2017 CAK95_RS02190 8a517d16516fe288938433228db3bb8a 343 Pfam PF09084 NMT1/THI5 like 61 264 1.8E-17 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS18810 c8cf4d5d959eb92fb5cf67ca31df608d 135 Pfam PF05443 ROS/MUCR transcriptional regulator protein 7 130 1.3E-50 T 06-07-2017 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 CAK95_RS14995 58e0c52a4d6ce30af781eb24d22a6477 107 Pfam PF08770 Sulphur oxidation protein SoxZ 12 102 1.3E-27 T 06-07-2017 IPR014880 Sulphur oxidation protein SoxZ CAK95_RS14995 58e0c52a4d6ce30af781eb24d22a6477 107 Gene3D G3DSA:2.60.40.10 6 105 2.6E-29 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK95_RS14995 58e0c52a4d6ce30af781eb24d22a6477 107 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 12 104 9.5E-27 T 06-07-2017 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ CAK95_RS14995 58e0c52a4d6ce30af781eb24d22a6477 107 SUPERFAMILY SSF81296 2 104 2.1E-28 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK95_RS15320 c8c04a57d45ab2b555df0c3f6a14a6e8 137 Pfam PF07681 DoxX 9 86 2.0E-14 T 06-07-2017 IPR032808 DoxX family CAK95_RS25135 47defdebdcaad5fab688140e7da26e20 128 SUPERFAMILY SSF158634 1 128 4.18E-46 T 06-07-2017 CAK95_RS25135 47defdebdcaad5fab688140e7da26e20 128 Pfam PF12200 Domain of unknown function (DUF3597) 3 123 4.1E-49 T 06-07-2017 IPR022016 Domain of unknown function DUF3597 CAK95_RS24295 c2c294adbdee849169a9d7e4324f7c81 191 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 7 183 2.9E-74 T 06-07-2017 IPR018715 Protein of unknown function DUF2239 CAK95_RS08195 1842f881041015c8174c73b9822fc65f 176 Pfam PF03734 L,D-transpeptidase catalytic domain 30 175 6.9E-12 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS08195 1842f881041015c8174c73b9822fc65f 176 SUPERFAMILY SSF141523 102 175 9.55E-7 T 06-07-2017 CAK95_RS08195 1842f881041015c8174c73b9822fc65f 176 SUPERFAMILY SSF141523 29 64 9.55E-7 T 06-07-2017 CAK95_RS08195 1842f881041015c8174c73b9822fc65f 176 Gene3D G3DSA:2.40.440.10 29 60 1.2E-5 T 06-07-2017 CAK95_RS08195 1842f881041015c8174c73b9822fc65f 176 Gene3D G3DSA:2.40.440.10 98 175 1.2E-5 T 06-07-2017 CAK95_RS17770 95b9c7174f04e80ffd22ac044b89e5be 249 Pfam PF00923 Transaldolase 12 238 1.0E-36 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAK95_RS17770 95b9c7174f04e80ffd22ac044b89e5be 249 SUPERFAMILY SSF51569 11 234 5.25E-47 T 06-07-2017 CAK95_RS17770 95b9c7174f04e80ffd22ac044b89e5be 249 Gene3D G3DSA:3.20.20.70 11 212 1.3E-36 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS28470 692937e0b30ccce0f84f776c8b859553 204 Pfam PF03729 Short repeat of unknown function (DUF308) 95 166 2.5E-13 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK95_RS28470 692937e0b30ccce0f84f776c8b859553 204 Pfam PF03729 Short repeat of unknown function (DUF308) 32 98 6.7E-9 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK95_RS28470 692937e0b30ccce0f84f776c8b859553 204 Pfam PF03729 Short repeat of unknown function (DUF308) 153 201 5.5E-8 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK95_RS03200 cced374b158e241a34e36b3d32a69431 143 Gene3D G3DSA:3.90.1720.10 3 140 8.1E-22 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK95_RS03200 cced374b158e241a34e36b3d32a69431 143 SUPERFAMILY SSF54001 3 140 7.16E-17 T 06-07-2017 CAK95_RS03200 cced374b158e241a34e36b3d32a69431 143 TIGRFAM TIGR02219 phage_NlpC_fam: putative phage cell wall peptidase, NlpC/P60 family 7 139 1.2E-26 T 06-07-2017 IPR011929 NlpC/P60 family, putative phage cell wall peptidase CAK95_RS27300 48d2f2962c650c1b6488b8d69e97231f 196 Pfam PF13801 Heavy-metal resistance 91 174 9.7E-8 T 06-07-2017 IPR025961 Heavy-metal resistance protein CAK95_RS21200 4a08c958fe70ffe6ff6567638df8fc9a 131 Pfam PF13767 Domain of unknown function (DUF4168) 47 122 4.8E-13 T 06-07-2017 IPR025433 Domain of unknown function DUF4168 CAK95_RS22880 a310e7e1f1b673dc97ffc13e0c6ef28d 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 20.393 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK95_RS22880 a310e7e1f1b673dc97ffc13e0c6ef28d 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 1.6E-24 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK95_RS26945 266a8f26a29c410fd6f6056d6b90b1c6 348 Gene3D G3DSA:3.90.550.10 71 147 4.6E-4 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS26945 266a8f26a29c410fd6f6056d6b90b1c6 348 SUPERFAMILY SSF53448 16 196 3.52E-7 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS25090 4e400d4e7e2b18cbd85d9bcf1d527b51 173 Pfam PF08818 Domain of unknown function (DU1801) 73 165 9.6E-14 T 06-07-2017 IPR014922 Domain of unknown function DUF1801 CAK95_RS25090 4e400d4e7e2b18cbd85d9bcf1d527b51 173 SUPERFAMILY SSF159888 61 171 2.88E-27 T 06-07-2017 CAK95_RS25385 14c72ca67a203bb1e888123cc027c0fd 82 Pfam PF10387 Protein of unknown function (DUF2442) 7 71 1.5E-20 T 06-07-2017 IPR018841 Protein of unknown function DUF2442 CAK95_RS26655 eb5240e046665d15f16ac0a09a4fa146 365 SUPERFAMILY SSF53756 11 343 8.03E-58 T 06-07-2017 CAK95_RS26655 eb5240e046665d15f16ac0a09a4fa146 365 Pfam PF13439 Glycosyltransferase Family 4 18 118 1.6E-10 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK95_RS26655 eb5240e046665d15f16ac0a09a4fa146 365 Gene3D G3DSA:3.40.50.2000 166 302 7.2E-19 T 06-07-2017 CAK95_RS26655 eb5240e046665d15f16ac0a09a4fa146 365 Pfam PF00534 Glycosyl transferases group 1 174 303 5.7E-24 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS07340 4b899564b61784ec124acdd5b1ca33bd 450 Gene3D G3DSA:2.70.70.10 295 442 3.2E-27 T 06-07-2017 CAK95_RS07340 4b899564b61784ec124acdd5b1ca33bd 450 Pfam PF01551 Peptidase family M23 334 435 3.4E-21 T 06-07-2017 IPR016047 Peptidase M23 CAK95_RS07340 4b899564b61784ec124acdd5b1ca33bd 450 SUPERFAMILY SSF51261 301 439 3.31E-24 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK95_RS10885 fa689bcd93c2ca63955fc435ecb43245 86 Pfam PF06620 Protein of unknown function (DUF1150) 11 86 4.3E-32 T 06-07-2017 IPR009531 Protein of unknown function DUF1150 CAK95_RS16230 01468d854c3af7cf4a844ed681e2bbe4 354 Gene3D G3DSA:3.30.420.40 182 351 4.5E-17 T 06-07-2017 CAK95_RS16230 01468d854c3af7cf4a844ed681e2bbe4 354 SUPERFAMILY SSF53067 158 319 5.83E-17 T 06-07-2017 CAK95_RS22505 c3d1933c774c5b278e5d9e3107b2ad3a 179 Pfam PF02620 Uncharacterized ACR, COG1399 64 148 5.3E-8 T 06-07-2017 IPR003772 Protein of unknown function DUF177 CAK95_RS20675 42e70f805ef3e69d7fb85be0a2418f08 91 Pfam PF02583 Metal-sensitive transcriptional repressor 6 86 1.1E-30 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CAK95_RS08175 5c4fc2f439e2f795fc7204c94c2bc23c 77 Pfam PF09939 Uncharacterized protein conserved in bacteria (DUF2171) 7 70 4.3E-26 T 06-07-2017 IPR018684 Protein of unknown function DUF2171 CAK95_RS09935 2b283999e5ddef63c3778a4c1376be74 105 Pfam PF01042 Endoribonuclease L-PSP 1 102 2.9E-18 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK95_RS09935 2b283999e5ddef63c3778a4c1376be74 105 SUPERFAMILY SSF55298 1 104 1.88E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS09935 2b283999e5ddef63c3778a4c1376be74 105 Gene3D G3DSA:3.30.1330.40 1 104 3.9E-30 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK95_RS28625 6569f6fc5222e11401317901128c9fc7 365 Gene3D G3DSA:3.40.50.2300 158 293 1.8E-32 T 06-07-2017 CAK95_RS28625 6569f6fc5222e11401317901128c9fc7 365 Pfam PF02608 Basic membrane protein 37 317 4.4E-42 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CAK95_RS28625 6569f6fc5222e11401317901128c9fc7 365 Gene3D G3DSA:3.40.50.2300 36 157 1.2E-36 T 06-07-2017 CAK95_RS15715 983a0c64eddac9280c5887d36cd358c0 124 TIGRFAM TIGR02301 TIGR02301: TIGR02301 family protein 4 122 7.2E-44 T 06-07-2017 IPR012645 Conserved hypothetical protein CHP02301 CAK95_RS15715 983a0c64eddac9280c5887d36cd358c0 124 Pfam PF09539 Protein of unknown function (DUF2385) 28 122 5.4E-37 T 06-07-2017 IPR012645 Conserved hypothetical protein CHP02301 CAK95_RS04325 84b383dedbc0eab613f3ab8cd690866b 253 Pfam PF01925 Sulfite exporter TauE/SafE 15 241 3.0E-24 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS22930 a955adc43c2adf5370a04f0803d4bf07 422 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 12 422 9.1E-152 T 06-07-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 CAK95_RS22930 a955adc43c2adf5370a04f0803d4bf07 422 Pfam PF12704 MacB-like periplasmic core domain 38 249 8.7E-17 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAK95_RS22930 a955adc43c2adf5370a04f0803d4bf07 422 Pfam PF02687 FtsX-like permease family 282 415 1.8E-17 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK95_RS15660 f3080c1fd43e4be2c8714c1adcbee200 931 Pfam PF10101 Predicted membrane protein (DUF2339) 152 918 2.2E-128 T 06-07-2017 IPR019286 Protein of unknown function DUF2339, transmembrane CAK95_RS15660 f3080c1fd43e4be2c8714c1adcbee200 931 PIRSF PIRSF035905 1 928 3.5E-212 T 06-07-2017 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein CAK95_RS19475 83f03296ff93beaf66f52c10200379ec 107 Pfam PF05284 Protein of unknown function (DUF736) 3 100 2.2E-35 T 06-07-2017 IPR007948 Protein of unknown function DUF736 CAK95_RS04665 a9311c77edbf8494da68bd95907ab01d 68 Gene3D G3DSA:1.10.10.10 22 50 1.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS15565 f6157978218a135fa3701a78ae36dc12 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 276 5.8E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS01830 b8765a5ce09c81315904ad45600fc061 479 Pfam PF06904 Extensin-like protein C-terminus 266 408 9.4E-52 T 06-07-2017 IPR009683 Extensin-like, C-terminal CAK95_RS15615 83e8c660ba8ce89c9e1f46069f5a9f05 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 280 1.5E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS15680 5420978254324ef63b3574e7fd4840d3 269 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 107 234 8.7E-21 T 06-07-2017 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain CAK95_RS02525 57b72e59829fd298f6bfc746edf8cc36 87 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 11 82 4.4E-6 T 06-07-2017 IPR018754 Protein of unknown function DUF2285 CAK95_RS09890 e7a9612b4d79a0779b64291e455a4928 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 310 2.0E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS15415 dc1a37cca68a9ecfce6e01392f817d0c 179 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 72 160 9.0E-27 T 06-07-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CAK95_RS14525 ea5017334be65bfb04e27719462e63a1 160 Pfam PF01724 Domain of unknown function DUF29 23 158 3.1E-47 T 06-07-2017 IPR002636 Protein from unkown function DUF29 CAK95_RS25835 9df5c9fc036401f64178169ba83ffa04 448 Pfam PF03739 Predicted permease YjgP/YjgQ family 41 393 4.0E-65 T 06-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 CAK95_RS22805 3b2455359a5a7b380430b115fed626e7 340 Pfam PF05128 Domain of unknown function (DUF697) 175 332 7.0E-45 T 06-07-2017 IPR021147 Protein of unknown function DUF697 CAK95_RS22805 3b2455359a5a7b380430b115fed626e7 340 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 47 326 1.6E-72 T 06-07-2017 IPR006507 Uncharacterised protein family UPF0283 CAK95_RS16965 1010ba0944b9c29592f40c4fe9e86eb2 61 Pfam PF13318 Protein of unknown function (DUF4089) 11 59 1.2E-15 T 06-07-2017 IPR025148 Protein of unknown function DUF4089 CAK95_RS15625 0e79bb218d17ffa05d43d15fcb4b16f4 300 Gene3D G3DSA:2.60.120.10 200 281 1.7E-4 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS15625 0e79bb218d17ffa05d43d15fcb4b16f4 300 SUPERFAMILY SSF51182 146 279 7.84E-6 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS26045 1aefcfadb7db413c6cea500b171a8e1d 216 Pfam PF09976 Tetratricopeptide repeat-like domain 18 158 4.7E-16 T 06-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 CAK95_RS26240 f9942dbae56eda2b30755e9278173a10 210 Pfam PF13360 PQQ-like domain 73 205 1.7E-6 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAK95_RS26240 f9942dbae56eda2b30755e9278173a10 210 SUPERFAMILY SSF63829 18 207 9.15E-27 T 06-07-2017 CAK95_RS26240 f9942dbae56eda2b30755e9278173a10 210 Gene3D G3DSA:2.130.10.10 20 205 7.1E-19 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK95_RS13010 fe550d176b0772590f04f7c52a608af9 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 304 1.2E-26 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS04420 08ae184254861d1b1c599381366fbf70 218 Gene3D G3DSA:3.40.50.850 9 209 3.1E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS04420 08ae184254861d1b1c599381366fbf70 218 SUPERFAMILY SSF52499 9 206 2.62E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS04420 08ae184254861d1b1c599381366fbf70 218 Pfam PF00857 Isochorismatase family 12 201 1.5E-34 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK95_RS11780 5e155cb2cb85d8d666dab3a73ca4d215 117 Gene3D G3DSA:3.30.450.40 79 114 8.3E-6 T 06-07-2017 IPR029016 GAF domain-like CAK95_RS11780 5e155cb2cb85d8d666dab3a73ca4d215 117 Pfam PF01614 Bacterial transcriptional regulator 82 115 2.1E-5 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK95_RS15605 ad3983afc45b17e1f4519fc6befbc221 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 321 6.1E-45 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS15605 ad3983afc45b17e1f4519fc6befbc221 355 Gene3D G3DSA:1.10.3470.10 86 264 9.1E-4 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK95_RS08405 bad528e07065861225850592b1f3cc93 95 SUPERFAMILY SSF54909 1 80 9.65E-10 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS08405 bad528e07065861225850592b1f3cc93 95 Gene3D G3DSA:3.30.70.1060 2 81 4.9E-4 T 06-07-2017 CAK95_RS19040 1c4200eba1f9d64492cd9d694fbf1423 107 Pfam PF05521 Phage head-tail joining protein 8 101 4.7E-21 T 06-07-2017 IPR008767 Bacteriophage SPP1, head-tail adaptor CAK95_RS19040 1c4200eba1f9d64492cd9d694fbf1423 107 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 6 104 6.4E-11 T 06-07-2017 IPR008767 Bacteriophage SPP1, head-tail adaptor CAK95_RS11880 874ba40ba34cb08130853dc4fab1a406 83 Pfam PF04226 Transglycosylase associated protein 35 83 4.4E-14 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS02605 6a7c20c8b4634fb2dd7c5c70b1fdbba9 102 Pfam PF14216 Domain of unknown function (DUF4326) 9 81 3.8E-25 T 06-07-2017 IPR025475 Protein of unknown function DUF4326) CAK95_RS01015 1425d3ce52be3cfeebb7a223b251a461 390 Pfam PF13458 Periplasmic binding protein 26 363 6.0E-74 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK95_RS01015 1425d3ce52be3cfeebb7a223b251a461 390 Gene3D G3DSA:3.40.50.2300 284 348 1.0E-43 T 06-07-2017 CAK95_RS01015 1425d3ce52be3cfeebb7a223b251a461 390 Gene3D G3DSA:3.40.50.2300 21 149 1.0E-43 T 06-07-2017 CAK95_RS01015 1425d3ce52be3cfeebb7a223b251a461 390 SUPERFAMILY SSF53822 26 383 3.93E-86 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK95_RS04995 a65af69c57ec6ddf207ce19ea868c91e 261 Gene3D G3DSA:1.10.3720.10 55 242 2.8E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04995 a65af69c57ec6ddf207ce19ea868c91e 261 SUPERFAMILY SSF161098 57 240 1.01E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS04995 a65af69c57ec6ddf207ce19ea868c91e 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 243 4.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS26030 9deac474a7cc0c339aa32fdf6ffd612f 97 Pfam PF08734 GYD domain 4 92 7.1E-28 T 06-07-2017 IPR014845 Uncharacterised protein GYD CAK95_RS26030 9deac474a7cc0c339aa32fdf6ffd612f 97 Gene3D G3DSA:3.30.70.920 38 67 3.4E-5 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK95_RS13685 08d91cfe9b319ed698c0cd1b825b32b2 458 Pfam PF05292 Malonyl-CoA decarboxylase (MCD) 82 416 1.0E-137 T 06-07-2017 IPR007956 Malonyl-CoA decarboxylase GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390918 CAK95_RS11985 5f9551098c22064219e14c794c774461 160 Pfam PF07617 Protein of unknown function (DUF1579) 4 158 3.1E-64 T 06-07-2017 IPR011473 Protein of unknown function DUF1579 CAK95_RS12230 30b94a024510b495cefb144f8009f0d6 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 319 1.2E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS28760 60dd2a9ba9d0a1d7590084e9531fdaee 250 SUPERFAMILY SSF161098 52 238 2.49E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28760 60dd2a9ba9d0a1d7590084e9531fdaee 250 Gene3D G3DSA:1.10.3720.10 50 245 2.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS28760 60dd2a9ba9d0a1d7590084e9531fdaee 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 244 1.1E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS10875 512072562e73b31c79233c36bfe9ae25 203 Gene3D G3DSA:1.20.910.10 6 198 5.8E-73 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS10875 512072562e73b31c79233c36bfe9ae25 203 Pfam PF01126 Heme oxygenase 15 197 1.2E-23 T 06-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS10875 512072562e73b31c79233c36bfe9ae25 203 SUPERFAMILY SSF48613 14 198 6.35E-54 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK95_RS13185 4612f5484550249a3ef22b66b8e0f10a 313 SUPERFAMILY SSF48239 45 202 1.12E-12 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS13185 4612f5484550249a3ef22b66b8e0f10a 313 Gene3D G3DSA:1.50.10.20 137 211 6.5E-9 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS13185 4612f5484550249a3ef22b66b8e0f10a 313 Gene3D G3DSA:1.50.10.20 50 91 6.5E-9 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAK95_RS05970 37c4bbfaa423921392b5ba652291dc00 329 SUPERFAMILY SSF51735 24 313 1.9E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS05970 37c4bbfaa423921392b5ba652291dc00 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 24 188 4.6E-5 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK95_RS05970 37c4bbfaa423921392b5ba652291dc00 329 Gene3D G3DSA:3.40.50.720 24 305 5.7E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 Pfam PF06725 3D domain 367 444 2.7E-23 T 06-07-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 SUPERFAMILY SSF50685 87 449 2.55E-119 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 Pfam PF03562 MltA specific insert domain 106 345 9.1E-75 T 06-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 SMART SM00925 191 345 6.6E-78 T 06-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 Gene3D G3DSA:2.40.40.10 256 451 5.3E-50 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS08035 1c897cb8a21cc8010151b5e0aba70e5f 526 Gene3D G3DSA:2.40.40.10 95 251 1.1E-31 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAK95_RS19265 ad7752c104254cdef2b97914ef036db3 340 SUPERFAMILY SSF51556 1 335 1.28E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK95_RS19265 ad7752c104254cdef2b97914ef036db3 340 Gene3D G3DSA:3.20.20.140 4 337 3.5E-77 T 06-07-2017 CAK95_RS19265 ad7752c104254cdef2b97914ef036db3 340 Pfam PF04909 Amidohydrolase 59 335 1.5E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK95_RS06880 46a2bffda99e17e96ae4aa79a31bfa99 153 SUPERFAMILY SSF46785 3 136 5.54E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06880 46a2bffda99e17e96ae4aa79a31bfa99 153 Gene3D G3DSA:1.10.10.10 1 138 4.0E-43 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS06880 46a2bffda99e17e96ae4aa79a31bfa99 153 Pfam PF02082 Transcriptional regulator 1 81 3.1E-22 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK95_RS19595 f2314bb3a128830193d7f8cece7d3f48 89 PIRSF PIRSF017854 4 89 4.8E-35 T 06-07-2017 IPR016704 Conjugal transfer, TrbD CAK95_RS19595 f2314bb3a128830193d7f8cece7d3f48 89 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 12 83 1.7E-11 T 06-07-2017 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB CAK95_RS00825 0184b287449c6b1ca394a51713878f9c 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 290 1.2E-12 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS01560 bf05b50087a8985ce49febf55562b005 186 SUPERFAMILY SSF54427 99 170 4.64E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS01560 bf05b50087a8985ce49febf55562b005 186 Pfam PF07366 SnoaL-like polyketide cyclase 102 168 9.4E-11 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS01560 bf05b50087a8985ce49febf55562b005 186 Gene3D G3DSA:3.10.450.50 91 169 1.6E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS18955 7cb1f1c5a501a67bcd9df1f7331f59ff 446 Pfam PF03237 Terminase-like family 63 432 3.6E-48 T 06-07-2017 IPR004921 Terminase, large subunit CAK95_RS14805 0c3186cfec840bb717762742ee980ee1 134 Pfam PF07813 LTXXQ motif family protein 30 119 1.7E-7 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS26005 f4d88e673565bc4b9e4f32c73e782b52 159 Gene3D G3DSA:2.60.40.420 35 159 4.6E-35 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS26005 f4d88e673565bc4b9e4f32c73e782b52 159 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 50 159 8.7E-11 T 06-07-2017 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CAK95_RS26005 f4d88e673565bc4b9e4f32c73e782b52 159 SUPERFAMILY SSF49503 51 159 2.11E-29 T 06-07-2017 IPR008972 Cupredoxin CAK95_RS07515 3cd87413a57e4e0ab1a8ee2b762042a7 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 2 175 2.6E-46 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAK95_RS07515 3cd87413a57e4e0ab1a8ee2b762042a7 185 Gene3D G3DSA:3.90.1140.10 3 178 1.6E-47 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAK95_RS07515 3cd87413a57e4e0ab1a8ee2b762042a7 185 Pfam PF13563 2'-5' RNA ligase superfamily 34 158 3.2E-18 T 06-07-2017 CAK95_RS07515 3cd87413a57e4e0ab1a8ee2b762042a7 185 SUPERFAMILY SSF55144 2 176 6.63E-42 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAK95_RS07515 3cd87413a57e4e0ab1a8ee2b762042a7 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 176 24.126 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAK95_RS03215 991e14b8cc461da5410ac66c27feab17 443 SUPERFAMILY SSF49842 310 442 4.14E-11 T 06-07-2017 IPR008983 Tumour necrosis factor-like domain GO:0005515 CAK95_RS03215 991e14b8cc461da5410ac66c27feab17 443 Pfam PF10983 Protein of unknown function (DUF2793) 23 108 1.3E-33 T 06-07-2017 IPR021251 Protein of unknown function DUF2793 CAK95_RS03215 991e14b8cc461da5410ac66c27feab17 443 Gene3D G3DSA:2.60.120.40 325 441 4.3E-12 T 06-07-2017 IPR008983 Tumour necrosis factor-like domain GO:0005515 CAK95_RS17200 5c301b98dad3f471af1f3d4f1fd58086 318 Pfam PF09084 NMT1/THI5 like 44 250 4.6E-18 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS17200 5c301b98dad3f471af1f3d4f1fd58086 318 SUPERFAMILY SSF53850 28 252 4.11E-31 T 06-07-2017 CAK95_RS17200 5c301b98dad3f471af1f3d4f1fd58086 318 Gene3D G3DSA:3.40.190.10 113 237 2.1E-11 T 06-07-2017 CAK95_RS06645 1b90659f957cf1d529b3e0b7bc0378a4 168 Pfam PF01478 Type IV leader peptidase family 10 112 8.0E-14 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CAK95_RS11980 22c3c566d94413f6d2325106c760cfae 153 Gene3D G3DSA:3.10.450.50 6 128 4.6E-26 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS11980 22c3c566d94413f6d2325106c760cfae 153 SUPERFAMILY SSF54427 2 130 2.51E-25 T 06-07-2017 IPR032710 NTF2-like domain CAK95_RS11980 22c3c566d94413f6d2325106c760cfae 153 Pfam PF13474 SnoaL-like domain 10 131 5.8E-17 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK95_RS16125 9e6d4516bdc6019b83985052cdd6b318 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 314 2.8E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS16810 c7a594d4db9860c4a8edd2b7bdca8955 430 Pfam PF00557 Metallopeptidase family M24 202 410 9.1E-32 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS16810 c7a594d4db9860c4a8edd2b7bdca8955 430 Gene3D G3DSA:3.90.230.10 192 425 1.9E-41 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS16810 c7a594d4db9860c4a8edd2b7bdca8955 430 SUPERFAMILY SSF55920 194 422 7.59E-44 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK95_RS13200 067f848117c193df13890e6c9944ca2c 275 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 264 1.2E-58 T 06-07-2017 IPR018648 Protein of unknown function DUF2076 CAK95_RS03820 e7b2bcfd6c18db2f1baca7c10b1ac81a 226 Pfam PF05170 AsmA family 103 222 1.3E-13 T 06-07-2017 IPR007844 AsmA CAK95_RS13140 9232119d64cf7677276b78db1f804d22 139 Pfam PF03724 META domain 43 128 9.9E-10 T 06-07-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ CAK95_RS14015 b8a9a370a0401c260e971d343697a271 203 Pfam PF01810 LysE type translocator 11 201 3.3E-34 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS14015 b8a9a370a0401c260e971d343697a271 203 PIRSF PIRSF006324 1 203 6.1E-47 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS22010 b529b75c79ab9106526922c0ec7d5556 289 Pfam PF08904 Domain of unknown function (DUF1849) 37 282 1.0E-88 T 06-07-2017 IPR015000 Protein of unknown function DUF1849 CAK95_RS00485 5d6b44df9267621ce4ccc42b31d1db30 359 Pfam PF07486 Cell Wall Hydrolase 189 299 3.7E-23 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 CAK95_RS26500 87c0e81aa7200b86ee65fb8c32ee880f 233 PRINTS PR01217 Proline rich extensin signature 85 106 1.4E-12 T 06-07-2017 CAK95_RS26500 87c0e81aa7200b86ee65fb8c32ee880f 233 PRINTS PR01217 Proline rich extensin signature 107 123 1.4E-12 T 06-07-2017 CAK95_RS26500 87c0e81aa7200b86ee65fb8c32ee880f 233 PRINTS PR01217 Proline rich extensin signature 124 141 1.4E-12 T 06-07-2017 CAK95_RS26500 87c0e81aa7200b86ee65fb8c32ee880f 233 PRINTS PR01217 Proline rich extensin signature 150 175 1.4E-12 T 06-07-2017 CAK95_RS26230 443c6febcacc21e0749370a8a9527ede 245 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 219 6.1E-83 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like CAK95_RS08670 c840be26f80ebbb584397c46a9638eb3 96 Pfam PF02325 YGGT family 10 87 1.7E-20 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 CAK95_RS23620 ad8352dfaf7f99806a7cbb4f77958902 222 Pfam PF01323 DSBA-like thioredoxin domain 10 210 2.0E-45 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAK95_RS23620 ad8352dfaf7f99806a7cbb4f77958902 222 SUPERFAMILY SSF52833 6 216 1.36E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS23620 ad8352dfaf7f99806a7cbb4f77958902 222 Gene3D G3DSA:3.40.30.10 6 210 2.9E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK95_RS08790 d201be6f724b4ceffb31e4825f2dc8f3 320 PIRSF PIRSF017082 3 319 1.9E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08790 d201be6f724b4ceffb31e4825f2dc8f3 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 316 8.3E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS08790 d201be6f724b4ceffb31e4825f2dc8f3 320 SUPERFAMILY SSF53850 110 277 2.06E-10 T 06-07-2017 CAK95_RS07810 a74981979b2c321d0195c57b1f7b2e9f 258 Pfam PF00174 Oxidoreductase molybdopterin binding domain 104 247 9.5E-29 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS07810 a74981979b2c321d0195c57b1f7b2e9f 258 Gene3D G3DSA:3.90.420.10 97 255 6.1E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS07810 a74981979b2c321d0195c57b1f7b2e9f 258 SUPERFAMILY SSF56524 55 257 1.83E-58 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK95_RS04695 c51a9297b4cf6a70a5e25aa80747fcc8 342 SUPERFAMILY SSF53850 30 270 1.53E-36 T 06-07-2017 CAK95_RS04695 c51a9297b4cf6a70a5e25aa80747fcc8 342 Pfam PF09084 NMT1/THI5 like 45 259 1.2E-48 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS04695 c51a9297b4cf6a70a5e25aa80747fcc8 342 Gene3D G3DSA:3.40.190.10 118 253 2.5E-14 T 06-07-2017 CAK95_RS06910 e64233712c354cf50b21c1a6a28e2109 239 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 213 6.8E-19 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK95_RS26000 09117120b395582dce0cecd618f3cc6a 100 Pfam PF11604 Copper binding periplasmic protein CusF 31 98 3.1E-26 T 06-07-2017 IPR021647 Copper binding periplasmic protein CusF CAK95_RS16800 4c3e9017dbd0bd08c2df12d85fb3bf71 370 Pfam PF12698 ABC-2 family transporter protein 26 362 3.9E-32 T 06-07-2017 CAK95_RS00915 9c16e8ccc2d725225e6a0629d0934755 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 309 2.6E-29 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS08515 869744e084ace8fcda3f13c1ab3d2ae8 275 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 40 163 8.5E-38 T 06-07-2017 IPR007621 TPM domain CAK95_RS00025 19bcd4de663124b443a78ed607281d0c 170 Pfam PF11937 Protein of unknown function (DUF3455) 33 163 6.2E-29 T 06-07-2017 IPR021851 Protein of unknown function DUF3455 CAK95_RS21985 89b11456b1d2e125fdcaf3f866e85de1 115 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 12 108 1.7E-10 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD CAK95_RS00460 d1fd121541a2ccc50b9cca15217c660a 412 SUPERFAMILY SSF103473 14 399 1.14E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS00460 d1fd121541a2ccc50b9cca15217c660a 412 Pfam PF07690 Major Facilitator Superfamily 24 363 9.0E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK95_RS00460 d1fd121541a2ccc50b9cca15217c660a 412 Gene3D G3DSA:1.20.1250.20 222 403 2.8E-18 T 06-07-2017 CAK95_RS00460 d1fd121541a2ccc50b9cca15217c660a 412 Gene3D G3DSA:1.20.1250.20 19 197 1.4E-17 T 06-07-2017 CAK95_RS20305 3bd6aca53f0d8530ac29dc93546dac09 458 Pfam PF11862 Domain of unknown function (DUF3382) 15 113 8.1E-13 T 06-07-2017 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal CAK95_RS20305 3bd6aca53f0d8530ac29dc93546dac09 458 Pfam PF02653 Branched-chain amino acid transport system / permease component 130 425 5.3E-53 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS07540 5b97174c6e0a5e352a01b3ce175e9d86 252 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 26 247 8.4E-62 T 06-07-2017 CAK95_RS17830 dc94d6b06cc5ca9facdaf7d7d66609c4 192 PIRSF PIRSF016919 1 190 1.2E-54 T 06-07-2017 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CAK95_RS17830 dc94d6b06cc5ca9facdaf7d7d66609c4 192 Pfam PF04955 HupE / UreJ protein 9 186 7.1E-56 T 06-07-2017 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CAK95_RS22875 56d45d39fe5b03d711642688d79b0ed0 204 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 166 1.1E-39 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK95_RS05360 e9670acb8e65b907bf6826518cbe6036 198 Pfam PF09335 SNARE associated Golgi protein 33 150 3.7E-14 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK95_RS14590 813f6f8b1c7910a2790dc50084344191 161 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 24 156 5.3E-16 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS01515 5ba3dacd2a6710b4b3782309f640b1e1 27 Pfam PF07886 BA14K-like protein 1 26 3.6E-14 T 06-07-2017 IPR012413 BA14k family GO:0009405 CAK95_RS19345 2ecbd15136da1d85e570f6e2d854a382 110 Pfam PF09919 Uncharacterized conserved protein (DUF2149) 14 101 2.6E-26 T 06-07-2017 IPR018676 Protein of unknown function DUF2149 CAK95_RS27865 67c998018cef0937201047e87b7f0e58 255 Pfam PF16917 Biotin/lipoate A/B protein ligase family 19 200 6.9E-55 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAK95_RS27865 67c998018cef0937201047e87b7f0e58 255 Gene3D G3DSA:3.30.930.10 26 202 1.3E-47 T 06-07-2017 CAK95_RS24860 04a9ac97eba16b53d8686595326c8a6e 193 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 45 169 3.5E-22 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS27755 c4997ffe0731af515a9683a042c91808 628 Pfam PF02653 Branched-chain amino acid transport system / permease component 352 606 1.2E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS27755 c4997ffe0731af515a9683a042c91808 628 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 290 5.1E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS10270 3c5a8eb2033b8aa6a32d3cf20f8ca2a1 158 Pfam PF01475 Ferric uptake regulator family 32 148 3.8E-11 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAK95_RS10270 3c5a8eb2033b8aa6a32d3cf20f8ca2a1 158 Gene3D G3DSA:1.10.10.10 23 92 7.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS10270 3c5a8eb2033b8aa6a32d3cf20f8ca2a1 158 SUPERFAMILY SSF46785 24 155 3.53E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS18640 9847d5110bdc1acf1688638d7a9914b2 798 Pfam PF14326 Domain of unknown function (DUF4384) 643 720 1.1E-16 T 06-07-2017 IPR025493 Domain of unknown function DUF4384 CAK95_RS28870 afcf6fb5a7aedde150acb4dab9db0f44 95 Gene3D G3DSA:3.40.50.1820 2 87 6.1E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS28870 afcf6fb5a7aedde150acb4dab9db0f44 95 SUPERFAMILY SSF53474 2 86 4.41E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK95_RS15765 6dc37f5a6e1be85176accab8cbef463e 93 Pfam PF12071 Protein of unknown function (DUF3551) 11 58 2.6E-6 T 06-07-2017 IPR021937 Protein of unknown function DUF3551 CAK95_RS27715 7d5d9754ddb93720da6dc67f66533096 137 Pfam PF12903 Protein of unknown function (DUF3830) 5 135 1.2E-32 T 06-07-2017 IPR024532 Protein of unknown function DUF3830 CAK95_RS10480 d5c4a4839f1d873738305e54571afc9b 521 SUPERFAMILY SSF141523 56 175 3.27E-9 T 06-07-2017 CAK95_RS12445 a5f6fe0de7bef33dd6a35c50a610a793 277 Pfam PF01925 Sulfite exporter TauE/SafE 18 270 6.5E-39 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS11805 bc47ea9e26e19d5924da4ccd50d57dcc 543 Pfam PF02538 Hydantoinase B/oxoprolinase 13 529 4.9E-134 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS09615 a4434bec983e1c89042eccc56e4ece35 467 Pfam PF01554 MatE 252 402 1.8E-16 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS09615 a4434bec983e1c89042eccc56e4ece35 467 Pfam PF01554 MatE 23 184 1.4E-20 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS09615 a4434bec983e1c89042eccc56e4ece35 467 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 411 2.0E-49 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS09615 a4434bec983e1c89042eccc56e4ece35 467 PIRSF PIRSF006603 1 456 6.5E-80 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK95_RS20915 19e894ff29212a377564b36cbab6ae46 188 SUPERFAMILY SSF48452 80 175 4.74E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS20915 19e894ff29212a377564b36cbab6ae46 188 Pfam PF14559 Tetratricopeptide repeat 117 182 1.2E-5 T 06-07-2017 CAK95_RS20915 19e894ff29212a377564b36cbab6ae46 188 Gene3D G3DSA:1.25.40.10 69 167 1.9E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK95_RS07350 afcea4e36c6e077cdfe815581c9b3ae1 390 Gene3D G3DSA:3.20.20.370 158 384 2.0E-71 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK95_RS07350 afcea4e36c6e077cdfe815581c9b3ae1 390 Pfam PF04748 Divergent polysaccharide deacetylase 170 383 5.2E-66 T 06-07-2017 IPR006837 Divergent polysaccharide deacetylase CAK95_RS07350 afcea4e36c6e077cdfe815581c9b3ae1 390 SUPERFAMILY SSF88713 166 383 7.34E-63 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK95_RS14820 f739e0fb5affdd46db61ea755c66a97a 155 Pfam PF07813 LTXXQ motif family protein 43 138 8.4E-12 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAK95_RS19505 9c0afdb654c7a701ce5c4730cb95352c 292 Pfam PF10134 Replication initiator protein A 24 253 6.1E-94 T 06-07-2017 IPR018777 Replication initiator protein A CAK95_RS09530 9587a678d95add267ec53998290d0f4d 126 Pfam PF03640 Secreted repeat of unknown function 27 69 1.8E-15 T 06-07-2017 IPR005297 Lipoprotein repeat CAK95_RS09530 9587a678d95add267ec53998290d0f4d 126 Pfam PF03640 Secreted repeat of unknown function 81 124 5.6E-20 T 06-07-2017 IPR005297 Lipoprotein repeat CAK95_RS09530 9587a678d95add267ec53998290d0f4d 126 PIRSF PIRSF029720 1 126 6.3E-52 T 06-07-2017 IPR014558 Uncharacterised conserved lipoprotein CAK95_RS09820 7c59d7ae8e6f60fe824a70595b235ccb 225 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 58 189 3.6E-22 T 06-07-2017 IPR010319 Transglutaminase-like cysteine peptidase, predicted CAK95_RS09820 7c59d7ae8e6f60fe824a70595b235ccb 225 SUPERFAMILY SSF54001 116 208 5.56E-10 T 06-07-2017 CAK95_RS18610 dd99c41d8593b1c049545924850c40ed 120 Pfam PF03779 SPW repeat 61 108 4.8E-10 T 06-07-2017 IPR005530 SPW repeat CAK95_RS18610 dd99c41d8593b1c049545924850c40ed 120 Pfam PF03779 SPW repeat 12 55 9.4E-11 T 06-07-2017 IPR005530 SPW repeat CAK95_RS18610 dd99c41d8593b1c049545924850c40ed 120 Gene3D G3DSA:1.20.120.80 14 114 9.2E-4 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS20870 a91b221d7d90714fb5ab042a6d499d85 489 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 87 344 1.1E-70 T 06-07-2017 IPR019285 Protein of unknown function DUF2336 CAK95_RS02580 2d13859f70d65a2caa02d7b5d9d28247 104 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 13 101 1.1E-26 T 06-07-2017 IPR009241 Toxin HigB-like CAK95_RS21855 662ca2b21de81a771b2474dc12980a55 406 Gene3D G3DSA:1.20.1250.20 14 192 1.5E-4 T 06-07-2017 CAK95_RS21855 662ca2b21de81a771b2474dc12980a55 406 SUPERFAMILY SSF103473 13 399 1.57E-14 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK95_RS10425 c679ae1ba318857e418ccbb2184523e3 159 Pfam PF06676 Protein of unknown function (DUF1178) 1 155 3.8E-56 T 06-07-2017 IPR009562 Protein of unknown function DUF1178 CAK95_RS10425 c679ae1ba318857e418ccbb2184523e3 159 PIRSF PIRSF032131 1 159 3.5E-56 T 06-07-2017 IPR009562 Protein of unknown function DUF1178 CAK95_RS28610 40013b1a4b57bcd012c6a7d2d916b684 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 275 4.8E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS27820 8eb731ba798b964e292fdfea472d477c 337 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 123 325 2.9E-49 T 06-07-2017 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 CAK95_RS27820 8eb731ba798b964e292fdfea472d477c 337 SUPERFAMILY SSF81342 119 325 1.57E-43 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK95_RS27820 8eb731ba798b964e292fdfea472d477c 337 Pfam PF01292 Prokaryotic cytochrome b561 125 304 3.1E-21 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAK95_RS27820 8eb731ba798b964e292fdfea472d477c 337 Gene3D G3DSA:1.20.950.20 119 328 2.1E-63 T 06-07-2017 CAK95_RS12970 0b4b8643d8683d7b8920e18319192223 381 Pfam PF03824 High-affinity nickel-transport protein 80 372 3.1E-60 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CAK95_RS26725 f230206a16925cc228d89bb4ac280ec8 245 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 205 5.2E-10 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK95_RS01460 32f02391c28bc9f262553fd1f74a67ae 342 SUPERFAMILY SSF53850 159 263 8.27E-5 T 06-07-2017 CAK95_RS01460 32f02391c28bc9f262553fd1f74a67ae 342 SUPERFAMILY SSF53850 48 122 8.27E-5 T 06-07-2017 CAK95_RS01460 32f02391c28bc9f262553fd1f74a67ae 342 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 316 4.0E-37 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS19895 ce84f633a97a61114843d2ea6b8bb8ab 196 Pfam PF03734 L,D-transpeptidase catalytic domain 67 194 2.9E-16 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK95_RS19895 ce84f633a97a61114843d2ea6b8bb8ab 196 SUPERFAMILY SSF141523 60 195 1.11E-32 T 06-07-2017 CAK95_RS19895 ce84f633a97a61114843d2ea6b8bb8ab 196 Gene3D G3DSA:2.40.440.10 59 195 5.7E-36 T 06-07-2017 CAK95_RS01700 c45ab1e08794d1dba1e56bb7edaade69 102 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 5 93 3.2E-14 T 06-07-2017 IPR013433 Putative polyhydroxyalkanoic acid system protein CAK95_RS10880 6cfb8d897950ff2d7979e9270d725a0d 92 Pfam PF06620 Protein of unknown function (DUF1150) 20 92 1.5E-22 T 06-07-2017 IPR009531 Protein of unknown function DUF1150 CAK95_RS22170 9aa2e43e5643d176965de41f31c4805b 377 Pfam PF00487 Fatty acid desaturase 95 339 8.6E-34 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK95_RS20565 6f5f31ecf82d84494988393e1c6333ee 89 Pfam PF06233 Usg-like family 9 88 5.1E-40 T 06-07-2017 IPR009354 Usg-like CAK95_RS26610 b56deb1b99c2602890fb9a50337d721e 151 Gene3D G3DSA:2.30.30.240 51 109 1.3E-14 T 06-07-2017 CAK95_RS26610 b56deb1b99c2602890fb9a50337d721e 151 SUPERFAMILY SSF50346 51 112 3.73E-16 T 06-07-2017 IPR011033 PRC-barrel-like CAK95_RS26610 b56deb1b99c2602890fb9a50337d721e 151 Pfam PF05239 PRC-barrel domain 52 109 3.5E-14 T 06-07-2017 IPR027275 PRC-barrel domain CAK95_RS18865 1a1ccb2d9b49fab9a115cf0edacab961 115 Pfam PF07372 Protein of unknown function (DUF1491) 3 111 1.8E-35 T 06-07-2017 IPR009964 Protein of unknown function DUF1491 CAK95_RS17170 099860534fa4df13ac62003a897497ca 168 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 168 3.0E-9 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS23535 facf18012b5a511fa7d92d585a0108d1 391 Pfam PF06181 Protein of unknown function (DUF989) 5 294 6.6E-119 T 06-07-2017 IPR010389 Domain of unknown function DUF989 CAK95_RS25255 f2113bdf537fb32b3a0a0a309c8a9064 249 Pfam PF09948 Predicted metal-binding integral membrane protein (DUF2182) 50 236 3.6E-71 T 06-07-2017 IPR018688 Protein of unknown function DUF2182, transmembrane, metal-binding CAK95_RS24820 2d32e82e4ee0500bb8370e399e0f840a 262 Pfam PF01925 Sulfite exporter TauE/SafE 11 254 2.6E-46 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS16090 abc7719ad44371c48a7e64389928b2fb 507 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 1.2E-151 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS02660 eb14517fee1efde7ada4521ab1c2304d 247 Pfam PF01925 Sulfite exporter TauE/SafE 10 245 8.1E-30 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS02505 16ad1c2e408e7caaba54023785554984 291 Pfam PF10134 Replication initiator protein A 23 252 1.9E-91 T 06-07-2017 IPR018777 Replication initiator protein A CAK95_RS08660 8f34708041a7e88ca182f2af73b0c56f 295 Pfam PF11769 Protein of unknown function (DUF3313) 33 228 4.5E-38 T 06-07-2017 IPR021747 Protein of unknown function DUF3313 CAK95_RS15860 e4b5be5bcef4099cfd7722b31ab72f21 120 Pfam PF16998 17 kDa outer membrane surface antigen 7 117 2.9E-30 T 06-07-2017 IPR032635 Surface antigen domain CAK95_RS00235 cd010185f0e9677c1656d0f5b35407c1 323 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 298 8.9E-29 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS03715 0fe0bce8c58e009a6e1a06a67623aec6 352 Pfam PF03601 Conserved hypothetical protein 698 31 328 2.0E-63 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CAK95_RS01155 f4237bd1fa88b7390b5f8c28050d6ee3 183 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 146 7.2E-14 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS10590 979a5708c93e1648ab07dcbda34bff98 487 Pfam PF01435 Peptidase family M48 71 254 2.8E-29 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK95_RS10590 979a5708c93e1648ab07dcbda34bff98 487 Gene3D G3DSA:3.30.2010.10 68 148 2.4E-18 T 06-07-2017 CAK95_RS02560 3a994693add75ec4e064a610500fc610 307 Pfam PF10686 Protein of unknown function (DUF2493) 194 260 6.4E-30 T 06-07-2017 IPR019627 Mycobacteriophage D29, Gp61 CAK95_RS26785 3f49a61bdfeab5561e08bea545f167fa 271 Pfam PF04116 Fatty acid hydroxylase superfamily 120 251 3.5E-24 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 CAK95_RS14560 95e6cba859676b54094cb4da2ae54d27 82 Pfam PF13770 Domain of unknown function (DUF4169) 2 56 8.0E-14 T 06-07-2017 IPR025227 Protein of unknown function DUF4169 CAK95_RS09700 6cca6233cd5f130fd1757db640a11564 250 Pfam PF01925 Sulfite exporter TauE/SafE 10 237 6.3E-20 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS26680 8e90fd519a51410536db2e170ee59249 438 Gene3D G3DSA:3.40.50.2000 251 374 4.7E-15 T 06-07-2017 CAK95_RS26680 8e90fd519a51410536db2e170ee59249 438 Pfam PF00534 Glycosyl transferases group 1 250 374 3.0E-15 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK95_RS26680 8e90fd519a51410536db2e170ee59249 438 SUPERFAMILY SSF53756 13 435 1.73E-39 T 06-07-2017 CAK95_RS14840 d6478db55e9c154d17129e884b58a724 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 274 2.1E-29 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS16260 001f5ab2faaf690c2d235ebc3366aa7e 102 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 21 84 6.0E-12 T 06-07-2017 IPR001607 Zinc finger, UBP-type GO:0008270 CAK95_RS16260 001f5ab2faaf690c2d235ebc3366aa7e 102 SUPERFAMILY SSF57850 4 86 7.65E-27 T 06-07-2017 CAK95_RS16260 001f5ab2faaf690c2d235ebc3366aa7e 102 Gene3D G3DSA:3.30.40.10 2 84 3.6E-23 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type CAK95_RS04285 171dc2b2c04013ad60d1af268b84c439 239 Pfam PF06242 Protein of unknown function (DUF1013) 35 173 5.4E-65 T 06-07-2017 IPR010421 Protein of unknown function DUF1013 CAK95_RS24245 1b7e5fbacd86b21c9be00a81e98f2dd7 572 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 86 260 3.5E-7 T 06-07-2017 CAK95_RS14685 58af35e24cbe6609c23d7c661020d4a6 198 Pfam PF01810 LysE type translocator 15 191 1.3E-20 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS25875 a8efb0641558f62c875b1b6105cfe945 295 Pfam PF03755 YicC-like family, N-terminal region 4 157 4.3E-37 T 06-07-2017 IPR013527 YicC-like, N-terminal CAK95_RS25875 a8efb0641558f62c875b1b6105cfe945 295 Pfam PF08340 Domain of unknown function (DUF1732) 211 295 2.4E-33 T 06-07-2017 IPR013551 Domain of unknown function DUF1732 CAK95_RS25875 a8efb0641558f62c875b1b6105cfe945 295 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 3 295 9.2E-69 T 06-07-2017 IPR005229 Conserved hypothetical protein CHP00255 CAK95_RS02455 f67f939e1e0619dc96242c4268f01712 150 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 48 1.9E-4 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK95_RS00435 4c2b8d9fb1e289f9dd650fda4a3cf59a 211 Pfam PF09347 Domain of unknown function (DUF1989) 15 178 8.1E-57 T 06-07-2017 IPR018959 Domain of unknown function DUF1989 CAK95_RS02450 941b95bb338bef584ee8e60d79d27e2e 207 Pfam PF12975 Domain of unknown function (DUF3859) 47 180 1.5E-7 T 06-07-2017 IPR024331 Domain of unknown function DUF3859 CAK95_RS24440 2ed73c1a44021cf790ec8ecbd5eb4a48 138 Pfam PF11367 Protein of unknown function (DUF3168) 9 127 3.4E-8 T 06-07-2017 IPR021508 Protein of unknown function DUF3168 CAK95_RS22385 9316cbf779402e8180b9eb8e6a7ca982 175 Pfam PF06271 RDD family 33 157 6.0E-14 T 06-07-2017 IPR010432 RDD CAK95_RS21940 11fb6b6a1b107f1c82624d8039b6c941 117 Pfam PF09361 Phasin protein 11 107 7.2E-25 T 06-07-2017 IPR018968 Phasin CAK95_RS02495 6596f5375e0b56a869ca3bae24bf60f4 169 Pfam PF11000 Protein of unknown function (DUF2840) 19 166 2.0E-74 T 06-07-2017 IPR021263 Protein of unknown function DUF2840 CAK95_RS06150 b96a2f81d7263f24ea85ae85311e5c95 162 Pfam PF07883 Cupin domain 56 126 6.9E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK95_RS06150 b96a2f81d7263f24ea85ae85311e5c95 162 Gene3D G3DSA:2.60.120.10 6 127 8.1E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS06150 b96a2f81d7263f24ea85ae85311e5c95 162 SUPERFAMILY SSF51182 44 141 6.16E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS09885 45181b776313cfbf7467f61b46444312 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 294 1.7E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS23555 7e3e69d1395c35a47f5ae72f25567c06 249 PIRSF PIRSF000851 17 248 1.4E-78 T 06-07-2017 IPR026027 Phosphatidylcholine synthase Pcs KEGG: 00564+2.7.8.24|MetaCyc: PWY-6826 CAK95_RS01985 73b3f16f755c75ff46e2aa97ef5c2b7d 71 Pfam PF06348 Protein of unknown function (DUF1059) 4 57 4.7E-13 T 06-07-2017 IPR009409 Protein of unknown function DUF1059 CAK95_RS17720 4b5896632e0f5f88136379e59ccec721 375 SUPERFAMILY SSF53756 93 360 4.32E-10 T 06-07-2017 CAK95_RS10760 c2da71818f2190488c3f219a59e63cb1 412 Pfam PF04932 O-Antigen ligase 193 348 7.3E-6 T 06-07-2017 IPR007016 O-antigen ligase-related CAK95_RS08835 107b3da069613839833920d3c173a190 304 SUPERFAMILY SSF55846 107 253 9.71E-5 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK95_RS25960 70155fa49df3dcc9e1b69384c30f9f70 219 Pfam PF02674 Colicin V production protein 6 145 1.4E-28 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAK95_RS23500 81cad131b72513633152144ca4daa577 298 Pfam PF04397 LytTr DNA-binding domain 194 277 3.8E-13 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAK95_RS23500 81cad131b72513633152144ca4daa577 298 SMART SM00850 184 281 4.6E-10 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAK95_RS07590 666a6e76704f25b939250603582ec13b 192 Pfam PF01810 LysE type translocator 3 190 9.2E-23 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK95_RS07030 991f70783f35785f9bea0a2b566ce702 311 Gene3D G3DSA:3.20.20.70 5 305 5.6E-110 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK95_RS07030 991f70783f35785f9bea0a2b566ce702 311 Pfam PF05853 beta-keto acid cleavage enzyme 6 303 4.7E-105 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 CAK95_RS23380 a8b18dafcd306aa396f60ae0cfb9cbe0 114 Pfam PF13856 ATP-binding sugar transporter from pro-phage 2 100 6.0E-5 T 06-07-2017 IPR025601 ATP-binding sugar transporter-like protein CAK95_RS09555 dcdb1883c8ba66386fb705f5c145e06e 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 321 5.7E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS09555 dcdb1883c8ba66386fb705f5c145e06e 326 PIRSF PIRSF017082 1 325 4.7E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAK95_RS09555 dcdb1883c8ba66386fb705f5c145e06e 326 SUPERFAMILY SSF53850 114 280 3.14E-10 T 06-07-2017 CAK95_RS05500 7df7c8e76013b3b14c210819757bf605 128 Pfam PF06170 Protein of unknown function (DUF983) 24 108 2.2E-33 T 06-07-2017 IPR009325 Protein of unknown function DUF983 CAK95_RS13725 45d561b4ce3a0cd5c4ff44c5743d3afa 417 Pfam PF04143 Sulphur transport 64 392 1.0E-76 T 06-07-2017 IPR007272 Sulphur transport domain CAK95_RS03960 6a4c9056b9ef012b6fdd9f929e12dc61 399 Pfam PF05940 NnrS protein 17 390 2.2E-107 T 06-07-2017 IPR010266 NnrS CAK95_RS27010 60c33e0f2f7924ef78d7ede4564484c9 347 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 320 9.9E-38 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS18665 22a007c0a628fcdf4191dcf342e7115a 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 325 8.6E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS24150 8d516e000d7e6573694ca34ffb8081e3 160 Pfam PF07681 DoxX 27 111 4.0E-16 T 06-07-2017 IPR032808 DoxX family CAK95_RS11210 079a4342e1bcaa0459cbff72a9f9fdff 191 SUPERFAMILY SSF53448 1 164 1.41E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS11210 079a4342e1bcaa0459cbff72a9f9fdff 191 Gene3D G3DSA:3.90.550.10 2 95 5.7E-6 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK95_RS21820 f734d714d4f13aa9eeb7ac90f36be59f 233 Pfam PF06823 Protein of unknown function (DUF1236) 164 232 3.7E-20 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS24170 9c58969ea9e52e9112429ca4b362745f 702 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 58 683 1.8E-148 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein CAK95_RS24170 9c58969ea9e52e9112429ca4b362745f 702 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 173 611 1.6E-86 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAK95_RS19610 deb8f0ae50ef9faab028a9d0dfb81a01 83 TIGRFAM TIGR04360 other_trbK: conjugative transfer region protein TrbK 2 74 1.1E-20 T 06-07-2017 IPR027587 Conjugative transfer region protein TrbK CAK95_RS12235 81e712ef617001da733529fbb076983c 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 279 9.5E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05960 afd2146e8f1a724b971b672f31bf3315 235 Gene3D G3DSA:1.10.3720.10 30 218 2.1E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05960 afd2146e8f1a724b971b672f31bf3315 235 SUPERFAMILY SSF161098 36 217 1.24E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS05960 afd2146e8f1a724b971b672f31bf3315 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 56 222 2.6E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK95_RS03590 a0358477369b04659c7a2f89d21775eb 71 Pfam PF13619 KTSC domain 8 66 7.3E-20 T 06-07-2017 IPR025309 KTSC domain CAK95_RS12630 9f19741ffc8c8fc0fbda6c60b2fb5af0 105 SUPERFAMILY SSF54909 13 99 2.74E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK95_RS28655 4f4b21e01635ed384c076694dd5761b3 333 Pfam PF09084 NMT1/THI5 like 46 249 1.4E-29 T 06-07-2017 IPR015168 SsuA/THI5-like CAK95_RS28655 4f4b21e01635ed384c076694dd5761b3 333 SUPERFAMILY SSF53850 34 257 2.85E-26 T 06-07-2017 CAK95_RS07115 55ec548ae2df90e026f384be0e076442 85 Pfam PF04226 Transglycosylase associated protein 32 81 1.9E-14 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK95_RS25220 6b2847fcfb605d6924bfa86a30a5e83a 252 Pfam PF06912 Protein of unknown function (DUF1275) 22 239 5.4E-26 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAK95_RS09655 59afed29e18b9fd185a8dd4f88c57927 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 292 5.2E-39 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS21910 fb9778da9841af7c643cd5f034a7957e 322 Pfam PF04773 FecR protein 118 213 8.4E-11 T 06-07-2017 IPR006860 FecR protein CAK95_RS16555 a3d591f7020fa1c2718c42a8ef6f387a 170 Pfam PF06282 Protein of unknown function (DUF1036) 19 131 1.3E-42 T 06-07-2017 IPR009380 Protein of unknown function DUF1036 CAK95_RS12360 aec541bea87663cfdf69af141650443a 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 8.4E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05465 6877c0d332196f20762c392985079d2b 173 Pfam PF06776 Invasion associated locus B (IalB) protein 39 172 5.2E-40 T 06-07-2017 IPR010642 Invasion protein B CAK95_RS05710 68809a405c026042ad0dc7c719806bd7 675 Pfam PF01757 Acyltransferase family 18 336 6.0E-25 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK95_RS20815 3e89c17fa6f82e4695b80484e135af06 139 Pfam PF04138 GtrA-like protein 11 131 2.6E-18 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAK95_RS10630 f26439bdf94a13fc815a5d04f7e0c808 110 SUPERFAMILY SSF51182 17 102 2.55E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS10630 f26439bdf94a13fc815a5d04f7e0c808 110 Gene3D G3DSA:2.60.120.10 19 92 7.2E-9 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK95_RS08000 cbb6194173d8da176033464d2034da87 165 Pfam PF10947 Protein of unknown function (DUF2628) 21 100 3.4E-14 T 06-07-2017 IPR024399 Protein of unknown function DUF2628 CAK95_RS02645 c112fc130171fd44b917099a4f43ae78 124 Pfam PF11171 Protein of unknown function (DUF2958) 3 106 3.9E-38 T 06-07-2017 IPR021341 Protein of unknown function DUF2958 CAK95_RS09990 b2b216b2082f66e0a6dd623c7254ae70 293 SUPERFAMILY SSF53850 57 217 1.85E-12 T 06-07-2017 CAK95_RS09990 b2b216b2082f66e0a6dd623c7254ae70 293 Gene3D G3DSA:3.40.190.10 96 179 1.2E-7 T 06-07-2017 CAK95_RS24865 1559a4e8f1075c84ef987e71d8591a24 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 312 1.7E-59 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS05900 4597b43709de258725962679a0777070 363 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 27 306 5.2E-14 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAK95_RS19590 62b5118da8ac12be7db02df0363137aa 110 Pfam PF04956 TrbC/VIRB2 family 6 100 2.8E-25 T 06-07-2017 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 CAK95_RS02850 4b10c3ba84b2c1666fabba950578f0f9 406 Pfam PF02646 RmuC family 108 382 4.7E-62 T 06-07-2017 IPR003798 DNA recombination RmuC CAK95_RS10010 4e12d151720acbca1651a12e7f79b21c 283 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 272 1.5E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS02430 7e41ffea2deea753ac95cad9dbfbf7b6 216 Pfam PF06532 Protein of unknown function (DUF1109) 14 215 1.0E-42 T 06-07-2017 IPR009495 Protein of unknown function DUF1109 CAK95_RS20220 753c2514ca6edd961839f48ea189d2b3 129 Pfam PF06059 Domain of Unknown Function (DUF930) 29 127 3.6E-35 T 06-07-2017 IPR009273 Protein of unknown function DUF930 CAK95_RS03120 e731d76860e819c675c2b4cc324f9bd5 491 Pfam PF05136 Phage portal protein, lambda family 25 362 1.3E-103 T 06-07-2017 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 CAK95_RS03120 e731d76860e819c675c2b4cc324f9bd5 491 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 27 466 1.1E-105 T 06-07-2017 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 CAK95_RS00815 9a701109f5a3f41d361b88232cee48ce 499 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 4.3E-112 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS15970 f1387459dd55510e1c8d0fe9b0e3431b 314 Pfam PF02219 Methylenetetrahydrofolate reductase 75 237 7.1E-11 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK95_RS15970 f1387459dd55510e1c8d0fe9b0e3431b 314 SUPERFAMILY SSF51730 66 297 1.16E-37 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS15970 f1387459dd55510e1c8d0fe9b0e3431b 314 Gene3D G3DSA:3.20.20.220 68 299 2.0E-32 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK95_RS10120 630d337072031e721ef6d70bd2ce69b6 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 290 1.5E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS04440 94a460738040f448b1066e95ceb3699f 283 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 270 4.2E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS01835 6363966d01fae79aa962030c632f4d35 74 Pfam PF11391 Protein of unknown function (DUF2798) 12 69 3.8E-18 T 06-07-2017 IPR021529 Protein of unknown function DUF2798 CAK95_RS13545 4a9e452489b31527049b20f91556be2e 428 Pfam PF01566 Natural resistance-associated macrophage protein 36 401 1.4E-84 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK95_RS14875 c6f4ff362d4d341aa0dfc4d50d490696 711 Pfam PF02538 Hydantoinase B/oxoprolinase 7 545 6.9E-124 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAK95_RS22250 68141d6ff49bd3ab464839b66f93b5b9 199 Pfam PF14235 Domain of unknown function (DUF4337) 22 189 3.4E-41 T 06-07-2017 IPR025570 Protein of unknown function DUF4337 CAK95_RS05095 24108c59a6b0268790b65a8fe96e48df 207 Pfam PF06186 Protein of unknown function (DUF992) 74 204 7.6E-42 T 06-07-2017 IPR009333 Protein of unknown function DUF992 CAK95_RS12180 90c81bce93a835105889346fbf94fc1a 120 Pfam PF04241 Protein of unknown function (DUF423) 20 100 1.0E-9 T 06-07-2017 IPR006696 Protein of unknown function DUF423 CAK95_RS01150 da1809acf6d69f7898b421734acf7a1d 328 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 22 300 2.9E-29 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAK95_RS01940 1a537de79d46225207a9eb0a03fa3e90 316 Pfam PF12889 Protein of unknown function (DUF3829) 37 312 4.0E-92 T 06-07-2017 IPR024291 Protein of unknown function DUF3829 CAK95_RS19095 79a36a163a8bdb0d47db231dc65a8394 155 Gene3D G3DSA:2.30.29.30 52 89 7.5E-5 T 06-07-2017 IPR011993 PH domain-like CAK95_RS19540 25ef235a8a3344bdb82af9f985cf9e78 579 Pfam PF11843 Protein of unknown function (DUF3363) 399 578 1.2E-59 T 06-07-2017 IPR021795 Protein of unknown function DUF3363 CAK95_RS19540 25ef235a8a3344bdb82af9f985cf9e78 579 Pfam PF11843 Protein of unknown function (DUF3363) 278 402 2.8E-34 T 06-07-2017 IPR021795 Protein of unknown function DUF3363 CAK95_RS17420 134e6596a51a0199736db815129b6718 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 1.1E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS15170 4c2f2892c2696497dd7e01da726bedc4 135 SUPERFAMILY SSF81558 14 102 1.86E-5 T 06-07-2017 IPR001280 Photosystem I PsaA/PsaB GO:0009522|GO:0009579|GO:0015979|GO:0016021 MetaCyc: PWY-101 CAK95_RS02535 373074404e2f0e5d9f2739cce9fef2c3 107 Pfam PF05284 Protein of unknown function (DUF736) 3 100 3.9E-34 T 06-07-2017 IPR007948 Protein of unknown function DUF736 CAK95_RS24435 2815fdc9a349ed8ccb8a28752ec9a88c 148 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 8 69 2.0E-4 T 06-07-2017 IPR010064 Bacteriophage HK97-gp10, putative tail-component CAK95_RS22160 f90a2642ab4bdd9599091ad246fe9c51 200 Pfam PF13787 Protein of unknown function with HXXEE motif 44 153 6.7E-20 T 06-07-2017 IPR025671 Protein of unknown function with HXXEE motif CAK95_RS19450 ffa9b8af295dcf6af6981507552e3d1b 349 Pfam PF13362 Toprim domain 239 327 4.0E-20 T 06-07-2017 IPR006171 Toprim domain CAK95_RS23930 6c83e326a95f54f86c2ab7fabe73c873 272 Pfam PF02616 Segregation and condensation protein ScpA 41 173 1.6E-12 T 06-07-2017 IPR003768 Segregation and condensation protein A CAK95_RS00820 ed6f358450e2dd81991b5d89c8e9578a 185 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 46 170 3.1E-13 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAK95_RS20145 3118b70b1ec7c19835d02bf2abb2e910 300 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 19 300 6.7E-38 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAK95_RS15340 5aabfbcc899212cb79d331e58b9f0d95 214 Pfam PF02108 Flagellar assembly protein FliH 62 178 6.0E-11 T 06-07-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CAK95_RS01595 6d351b9fbf2936c6dd184cbc01045ab1 200 Pfam PF06823 Protein of unknown function (DUF1236) 129 196 7.8E-12 T 06-07-2017 IPR009642 Protein of unknown function DUF1236 CAK95_RS13895 23bb58ecbac59cc1bb2853163f151f0e 96 Gene3D G3DSA:1.20.120.20 5 62 0.001 T 06-07-2017 CAK95_RS04075 4e01f166b316dee37909142e71171b23 283 Pfam PF01925 Sulfite exporter TauE/SafE 48 272 6.4E-19 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS23600 a26701d58bd05392f5ed93454113fd53 253 Pfam PF06776 Invasion associated locus B (IalB) protein 81 216 3.1E-32 T 06-07-2017 IPR010642 Invasion protein B CAK95_RS05550 d9fcb4015ec51184baa1ce8303712e23 125 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 55 107 3.5E-16 T 06-07-2017 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CAK95_RS03085 893869596d49ff8c6a755539b71fcf54 188 Pfam PF11994 Protein of unknown function (DUF3489) 121 186 2.3E-32 T 06-07-2017 IPR021880 Protein of unknown function DUF3489 CAK95_RS01025 10370c013805d1c5b9013cbc6d903b55 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 291 1.2E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS16010 dc5682ed3ff54aa723deb30158461673 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 70 345 1.4E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS13170 447ba37c645d3bde1a4384d15ec68faa 213 Pfam PF01865 Protein of unknown function DUF47 10 211 2.0E-42 T 06-07-2017 IPR018445 Putative phosphate transport regulator CAK95_RS19765 c75b2e4505c73af166b9a54aad8df133 243 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 12 222 9.7E-52 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK95_RS17460 0c4b6b7cb37d6aa04722cae912671507 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 1.2E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS14210 eabdcb600c518ffc1c006b9db2e2e934 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 440 7.1E-129 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAK95_RS18795 a067e9c4863d0cfa07c5570196f2498f 524 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 61 190 1.9E-10 T 06-07-2017 CAK95_RS11675 9306985bdeea95e6c6ce380a6dc853a2 63 Gene3D G3DSA:1.10.10.10 8 60 7.0E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS23210 99112486e457463f13f6d4ec553c580b 373 Pfam PF07007 Protein of unknown function (DUF1311) 32 98 8.4E-5 T 06-07-2017 IPR009739 Protein of unknown function DUF1311 CAK95_RS15110 5fd7fb4da6867b05166f0d0f990f43a6 270 Pfam PF11150 Protein of unknown function (DUF2927) 51 253 2.0E-56 T 06-07-2017 IPR021323 Protein of unknown function DUF2927 CAK95_RS28350 6325dbad068eaa7b18fd7024a63042d2 438 Pfam PF11902 Protein of unknown function (DUF3422) 14 429 3.5E-164 T 06-07-2017 IPR021830 Protein of unknown function DUF3422 CAK95_RS09340 fce57055e8ed2589becada581c23cd35 310 Pfam PF02104 SURF1 family 66 269 6.8E-43 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK95_RS01495 7d9a9bc9dc96fea20243c8b6e6a57b6a 74 Pfam PF02371 Transposase IS116/IS110/IS902 family 2 26 1.7E-4 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CAK95_RS05860 ce7f989a8e82146619d7e312c2c3b699 166 Pfam PF07750 GcrA cell cycle regulator 1 160 6.2E-61 T 06-07-2017 IPR011681 GcrA cell cycle regulator CAK95_RS08995 698f8f91b2556edbea4c8cb3d992124d 170 Pfam PF13924 Lipocalin-like domain 32 147 2.4E-16 T 06-07-2017 IPR024311 Lipocalin-like domain CAK95_RS13415 8e71be5934b6f76e19a1fd6771e7d558 83 Pfam PF13773 Domain of unknown function (DUF4170) 8 75 2.5E-40 T 06-07-2017 IPR025226 Protein of unknown function DUF4170 CAK95_RS17265 9975d11fae63e5a89f9a03f0349108a4 151 Pfam PF05425 Copper resistance protein D 46 145 1.5E-11 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 CAK95_RS02315 021333f194d34b623b37f66de1e29c43 400 Pfam PF03743 Bacterial conjugation TrbI-like protein 212 389 6.4E-62 T 06-07-2017 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI CAK95_RS10950 feca9bca48f2355c0a98314f513a9a2c 120 Pfam PF06305 Protein of unknown function (DUF1049) 25 94 2.4E-9 T 06-07-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CAK95_RS26980 82b929845f5b041bfc8e4369e4befa29 1196 SUPERFAMILY SSF49373 611 690 5.49E-6 T 06-07-2017 IPR008964 Invasin/intimin cell-adhesion fragments CAK95_RS27540 d769f92d80b2bfd88da83b4addd2da44 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 158 9.4E-19 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAK95_RS08420 4fe8bdc9cead565fec19168900ec806d 1436 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1082 1435 1.3E-55 T 06-07-2017 IPR007452 Translocation and assembly module TamB CAK95_RS24540 2fdbe8b13e564244446c5ebb4bb23808 159 SUPERFAMILY SSF51182 31 147 2.87E-8 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK95_RS16400 a48fa8f10ebdb0850deaf2c7d0db88aa 155 Pfam PF06186 Protein of unknown function (DUF992) 14 152 6.3E-50 T 06-07-2017 IPR009333 Protein of unknown function DUF992 CAK95_RS03735 fb3876d5168d854ba0f76c9877a52917 103 Pfam PF06155 Protein of unknown function (DUF971) 6 88 3.4E-21 T 06-07-2017 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 CAK95_RS26800 c2335646cca6e964e633d95d6063b907 418 Pfam PF05159 Capsule polysaccharide biosynthesis protein 85 391 8.3E-76 T 06-07-2017 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CAK95_RS02465 906f177388770a6658352318690ad873 109 Gene3D G3DSA:1.10.10.10 19 73 2.9E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK95_RS20240 a2717006f4de2463b2f1ef01c245ff99 85 Pfam PF13619 KTSC domain 14 71 2.6E-19 T 06-07-2017 IPR025309 KTSC domain CAK95_RS16460 43e42968378229ffcfc4a07a14330de6 314 Pfam PF13670 Peptidase propeptide and YPEB domain 6 82 1.2E-6 T 06-07-2017 IPR025711 PepSY domain CAK95_RS21530 78f6279672d852b18288d9342d69d0c1 344 Pfam PF02120 Flagellar hook-length control protein FliK 251 331 1.7E-15 T 06-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal CAK95_RS12865 c116cea1b4a5fb0f75f3b51e8ac9ca6e 187 Pfam PF03773 Predicted permease 55 180 3.8E-10 T 06-07-2017 IPR005524 Predicted permease DUF318 CAK95_RS07510 9bbb2e82552c835a175c118c3a72a36d 143 Gene3D G3DSA:3.40.630.30 8 123 1.8E-4 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK95_RS25300 6619aef75e20bf39c8cd2cc493bd8712 296 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 141 232 3.0E-35 T 06-07-2017 IPR019225 Protein of unknown function DUF2155 CAK95_RS11655 e5f6f002b7db14c91375d08f9248983c 663 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 291 1.1E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS11655 e5f6f002b7db14c91375d08f9248983c 663 Pfam PF02653 Branched-chain amino acid transport system / permease component 358 620 1.6E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK95_RS05625 b5b9f6e9ac1314becf26ed42e0b83139 308 Pfam PF01925 Sulfite exporter TauE/SafE 17 286 1.0E-49 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK95_RS18365 f906572eac4e0d49a52af0a1a1f6c598 264 Pfam PF14023 Protein of unknown function (DUF4239) 54 251 3.4E-18 T 06-07-2017 IPR025333 Protein of unknown function DUF4239