locus-tag	class	description
THETH_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THETH_RS00015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THETH_RS00020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THETH_RS00030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THETH_RS00030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THETH_RS00035	COG0741	lytic transglycosylase activity
THETH_RS00040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
THETH_RS00055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THETH_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
THETH_RS00065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THETH_RS00070	COG0443	Heat shock 70 kDa protein
THETH_RS00075	COG0071	Belongs to the small heat shock protein (HSP20) family
THETH_RS00080	COG0542	response to heat
THETH_RS00085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THETH_RS00090	COG1132	(ABC) transporter
THETH_RS00125	COG0601	transmembrane transport
THETH_RS00130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS00135	COG0444	Belongs to the ABC transporter superfamily
THETH_RS00140	COG4608	Belongs to the ABC transporter superfamily
THETH_RS00150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
THETH_RS00160	COG0191	fructose-bisphosphate aldolase activity
THETH_RS00165	COG0799	negative regulation of ribosome biogenesis
THETH_RS00170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THETH_RS00175	COG0416	fatty acid biosynthetic process
THETH_RS00180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
THETH_RS00200	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THETH_RS00220	COG0534	Mate efflux family protein
THETH_RS00230	COG0628	permease
THETH_RS00235	COG0489	protein tyrosine kinase activity
THETH_RS00240	COG0720	synthase
THETH_RS00245	COG1469	GTP cyclohydrolase I activity
THETH_RS00250	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
THETH_RS00260	COG0517	IMP dehydrogenase activity
THETH_RS00260	COG0516	GMP reductase activity
THETH_RS00285	COG1561	YicC-like family, N-terminal region
THETH_RS00290	COG2052	Domain of unknown function (DUF370)
THETH_RS00295	COG0194	GDP metabolic process
THETH_RS00300	COG1758	RNA polymerase activity
THETH_RS00305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THETH_RS00310	COG1376	ErfK ybiS ycfS ynhG family protein
THETH_RS00315	COG1098	S1 RNA binding domain
THETH_RS00320	COG0254	rRNA binding
THETH_RS00330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THETH_RS00335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THETH_RS00345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
THETH_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS00360	COG1737	Transcriptional regulator
THETH_RS00365	COG1045	serine acetyltransferase
THETH_RS00370	COG1773	rubredoxin
THETH_RS00375	COG1592	Rubrerythrin
THETH_RS00390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THETH_RS00395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
THETH_RS00405	COG0850	regulation of cytokinetic process
THETH_RS00410	COG1363	Peptidase, m42
THETH_RS00430	COG1596	polysaccharide export
THETH_RS00430	COG1555	photosystem II stabilization
THETH_RS00440	COG1137	ATPase activity
THETH_RS00450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THETH_RS00455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THETH_RS00460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THETH_RS00485	COG1116	anion transmembrane transporter activity
THETH_RS00490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THETH_RS00505	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THETH_RS00520	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THETH_RS00540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THETH_RS00545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THETH_RS00575	COG0275	rRNA processing
THETH_RS00585	COG0768	penicillin binding
THETH_RS00595	COG1013	pyruvate-flavodoxin oxidoreductase activity
THETH_RS00600	COG0674	pyruvate-flavodoxin oxidoreductase activity
THETH_RS00600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THETH_RS00610	COG0544	peptidyl-prolyl cis-trans isomerase activity
THETH_RS00615	COG0740	serine-type endopeptidase activity
THETH_RS00620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THETH_RS00630	COG1573	uracil-dna glycosylase
THETH_RS00635	COG1321	iron dependent repressor
THETH_RS00645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THETH_RS00645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THETH_RS00675	COG2182	Extracellular solute-binding protein
THETH_RS00680	COG1175	transmembrane transport
THETH_RS00685	COG3833	ABC-type maltose transport systems, permease component
THETH_RS00690	COG1940	carbohydrate kinase activity
THETH_RS00695	COG1472	Belongs to the glycosyl hydrolase 3 family
THETH_RS00705	COG0444	Belongs to the ABC transporter superfamily
THETH_RS00710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS00715	COG0601	transmembrane transport
THETH_RS00725	COG1312	Catalyzes the dehydration of D-mannonate
THETH_RS00730	COG0246	Mannitol dehydrogenase
THETH_RS00735	COG1486	melibiose metabolic process
THETH_RS00740	COG0179	Fumarylacetoacetate (FAA) hydrolase
THETH_RS00745	COG3458	cephalosporin-C deacetylase activity
THETH_RS00750	COG0601	transmembrane transport
THETH_RS00755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS00760	COG0444	Belongs to the ABC transporter superfamily
THETH_RS00765	COG4608	Belongs to the ABC transporter superfamily
THETH_RS00770	COG0747	negative chemotaxis
THETH_RS00775	COG3661	Belongs to the glycosyl hydrolase 67 family
THETH_RS00790	COG1070	Carbohydrate kinase
THETH_RS00795	COG3250	beta-galactosidase activity
THETH_RS00805	COG3328	transposase activity
THETH_RS00835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THETH_RS00845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THETH_RS00850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THETH_RS00855	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THETH_RS00865	COG2188	Transcriptional regulator
THETH_RS00885	COG4603	Belongs to the binding-protein-dependent transport system permease family
THETH_RS00890	COG1079	Belongs to the binding-protein-dependent transport system permease family
THETH_RS00910	COG0698	ribose 5-phosphate isomerase
THETH_RS00915	COG1366	Belongs to the anti-sigma-factor antagonist family
THETH_RS00920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
THETH_RS00930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
THETH_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THETH_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THETH_RS00945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
THETH_RS00950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
THETH_RS00955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THETH_RS00970	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
THETH_RS00970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
THETH_RS00975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
THETH_RS00980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THETH_RS00985	COG0129	dihydroxy-acid dehydratase activity
THETH_RS00990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
THETH_RS00995	COG0440	acetolactate synthase activity
THETH_RS01000	COG0028	Belongs to the TPP enzyme family
THETH_RS01005	COG0473	3-isopropylmalate dehydrogenase activity
THETH_RS01010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THETH_RS01015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THETH_RS01020	COG2176	DNA-directed DNA polymerase activity
THETH_RS01025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THETH_RS01030	COG0481	GTPase activity
THETH_RS01060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
THETH_RS01065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
THETH_RS01080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THETH_RS01085	COG1362	aminopeptidase activity
THETH_RS01115	COG2358	TRAP transporter, solute receptor (TAXI family
THETH_RS01120	COG2362	D-Aminopeptidase
THETH_RS01125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
THETH_RS01180	COG1328	CTP reductase activity
THETH_RS01180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THETH_RS01185	COG0300	oxidoreductase activity
THETH_RS01190	COG0540	Belongs to the ATCase OTCase family
THETH_RS01190	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
THETH_RS01200	COG1215	transferase activity, transferring glycosyl groups
THETH_RS01205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
THETH_RS01210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THETH_RS01215	COG3481	metal-dependent phosphohydrolase, HD sub domain
THETH_RS01230	COG0395	ABC-type sugar transport system, permease component
THETH_RS01235	COG1175	transmembrane transport
THETH_RS01245	COG1959	2 iron, 2 sulfur cluster binding
THETH_RS01250	COG2873	o-acetylhomoserine
THETH_RS01255	COG1959	2 iron, 2 sulfur cluster binding
THETH_RS01265	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
THETH_RS01270	COG1301	dicarboxylic acid transport
THETH_RS01275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THETH_RS01280	COG0494	nUDIX hydrolase
THETH_RS01285	COG0442	prolyl-tRNA aminoacylation
THETH_RS01290	COG0552	protein localization to endoplasmic reticulum
THETH_RS01305	COG3584	3D domain protein
THETH_RS01310	COG1959	2 iron, 2 sulfur cluster binding
THETH_RS01315	COG1956	GAF domain-containing protein
THETH_RS01320	COG0019	diaminopimelate decarboxylase activity
THETH_RS01325	COG0432	Pfam Uncharacterised protein family UPF0047
THETH_RS01335	COG2894	cell division
THETH_RS01345	COG1968	undecaprenyl-diphosphatase activity
THETH_RS01360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THETH_RS01360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THETH_RS01365	COG1406	Chemotaxis phosphatase CheX
THETH_RS01375	COG0356	it plays a direct role in the translocation of protons across the membrane
THETH_RS01380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THETH_RS01385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THETH_RS01390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THETH_RS01395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THETH_RS01400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THETH_RS01405	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
THETH_RS01410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THETH_RS01415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THETH_RS01430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
THETH_RS01435	COG1530	ribonuclease E activity
THETH_RS01440	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
THETH_RS01455	COG0835	chemotaxis
THETH_RS01460	COG0511	ligase activity, forming carbon-carbon bonds
THETH_RS01495	COG1523	belongs to the glycosyl hydrolase 13 family
THETH_RS01500	COG1757	Na H antiporter
THETH_RS01505	COG3437	response regulator, receiver
THETH_RS01515	COG1132	(ABC) transporter
THETH_RS01520	COG2890	protein-(glutamine-N5) methyltransferase activity
THETH_RS01525	COG2151	metal-sulfur cluster biosynthetic enzyme
THETH_RS01540	COG0450	alkyl hydroperoxide reductase
THETH_RS01555	COG0601	transmembrane transport
THETH_RS01560	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
THETH_RS01565	COG0617	tRNA 3'-terminal CCA addition
THETH_RS01565	COG3620	sequence-specific DNA binding
THETH_RS01565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THETH_RS01570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THETH_RS01575	COG1366	Belongs to the anti-sigma-factor antagonist family
THETH_RS01580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
THETH_RS01585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
THETH_RS01595	COG1160	GTP binding
THETH_RS01600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THETH_RS01615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THETH_RS01625	COG3250	beta-galactosidase activity
THETH_RS01630	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
THETH_RS01640	COG1175	transmembrane transport
THETH_RS01645	COG0395	ABC-type sugar transport system, permease component
THETH_RS01655	COG1737	Transcriptional regulator
THETH_RS01660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THETH_RS01665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THETH_RS01670	COG0166	Belongs to the GPI family
THETH_RS01680	COG0237	dephospho-CoA kinase activity
THETH_RS01700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
THETH_RS01710	COG2188	Transcriptional regulator
THETH_RS01715	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
THETH_RS01720	COG1472	Belongs to the glycosyl hydrolase 3 family
THETH_RS01725	COG2086	electron transfer activity
THETH_RS01730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
THETH_RS01735	COG0277	FAD linked oxidase domain protein
THETH_RS01740	COG0840	transmembrane signaling receptor activity
THETH_RS01745	COG0840	transmembrane signaling receptor activity
THETH_RS01775	COG1131	(ABC) transporter
THETH_RS01785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THETH_RS01790	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THETH_RS01795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THETH_RS01805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THETH_RS01805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THETH_RS01815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THETH_RS01825	COG1739	Uncharacterized protein family UPF0029
THETH_RS01830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
THETH_RS01835	COG0584	glycerophosphoryl diester phosphodiesterase
THETH_RS01865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THETH_RS01870	COG0305	Participates in initiation and elongation during chromosome replication
THETH_RS01895	COG2986	histidine ammonia-lyase
THETH_RS01910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
THETH_RS01915	COG1660	Displays ATPase and GTPase activities
THETH_RS01920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
THETH_RS01930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THETH_RS01935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THETH_RS01940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THETH_RS01950	COG0083	homoserine kinase activity
THETH_RS01955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THETH_RS01960	COG0460	homoserine dehydrogenase
THETH_RS01980	COG1175	transmembrane transport
THETH_RS01985	COG0395	ABC-type sugar transport system, permease component
THETH_RS01995	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
THETH_RS02000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
THETH_RS02025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THETH_RS02025	COG0674	pyruvate-flavodoxin oxidoreductase activity
THETH_RS02035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
THETH_RS02090	COG0745	RESPONSE REGULATOR receiver
THETH_RS02095	COG1846	Transcriptional regulator
THETH_RS02105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THETH_RS02110	COG1803	Methylglyoxal synthase
THETH_RS02150	COG1862	Preprotein translocase
THETH_RS02155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THETH_RS02160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THETH_RS02170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
THETH_RS02170	COG0426	domain, Protein
THETH_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS02185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
THETH_RS02190	COG4112	unkown
THETH_RS02195	COG1435	thymidine kinase activity
THETH_RS02200	COG4974	Belongs to the 'phage' integrase family
THETH_RS02210	COG0303	'Molybdopterin
THETH_RS02215	COG0521	Mo-molybdopterin cofactor biosynthetic process
THETH_RS02215	COG0315	cyclic pyranopterin monophosphate synthase activity
THETH_RS02220	COG1910	domain protein
THETH_RS02225	COG0058	SHG alpha-glucan phosphorylase activity
THETH_RS02230	COG0742	ribosomal rna small subunit methyltransferase
THETH_RS02235	COG1486	melibiose metabolic process
THETH_RS02245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
THETH_RS02250	COG1368	sulfuric ester hydrolase activity
THETH_RS02290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THETH_RS02295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
THETH_RS02305	COG0047	phosphoribosylformylglycinamidine synthase activity
THETH_RS02310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THETH_RS02315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
THETH_RS02320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
THETH_RS02325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
THETH_RS02330	COG0138	bifunctional purine biosynthesis protein purh
THETH_RS02335	COG0151	Belongs to the GarS family
THETH_RS02355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THETH_RS02370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS02375	COG0601	transmembrane transport
THETH_RS02380	COG4166	transmembrane transport
THETH_RS02400	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
THETH_RS02405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
THETH_RS02410	COG0157	Belongs to the NadC ModD family
THETH_RS02425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
THETH_RS02430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THETH_RS02430	COG0512	Glutamine amidotransferase of anthranilate synthase
THETH_RS02435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THETH_RS02440	COG0134	indole-3-glycerol-phosphate synthase activity
THETH_RS02445	COG0135	phosphoribosylanthranilate isomerase activity
THETH_RS02450	COG0133	tryptophan synthase activity
THETH_RS02455	COG0159	tryptophan synthase activity
THETH_RS02460	COG0077	Prephenate dehydratase
THETH_RS02460	COG1605	Chorismate mutase
THETH_RS02465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
THETH_RS02470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THETH_RS02475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
THETH_RS02480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
THETH_RS02485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THETH_RS02490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THETH_RS02505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THETH_RS02510	COG0473	3-isopropylmalate dehydrogenase activity
THETH_RS02515	COG0066	3-isopropylmalate dehydratase activity
THETH_RS02520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THETH_RS02525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THETH_RS02545	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
THETH_RS02575	COG0501	Belongs to the peptidase M48B family
THETH_RS02595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
THETH_RS02620	COG0673	inositol 2-dehydrogenase activity
THETH_RS02625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THETH_RS02635	COG1994	Peptidase M50
THETH_RS02655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
THETH_RS02670	COG0527	aspartate kinase activity
THETH_RS02670	COG0460	homoserine dehydrogenase
THETH_RS02675	COG1410	methionine synthase
THETH_RS02675	COG0646	methionine synthase
THETH_RS02690	COG0010	Belongs to the arginase family
THETH_RS02695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THETH_RS02700	COG0315	cyclic pyranopterin monophosphate synthase activity
THETH_RS02730	COG0745	RESPONSE REGULATOR receiver
THETH_RS02740	COG0573	inorganic phosphate transmembrane transporter activity
THETH_RS02750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THETH_RS02755	COG0704	Plays a role in the regulation of phosphate uptake
THETH_RS02770	COG0017	Asparaginyl-tRNA synthetase
THETH_RS02775	COG2255	four-way junction helicase activity
THETH_RS02780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
THETH_RS02790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THETH_RS02795	COG0704	Plays a role in the regulation of phosphate uptake
THETH_RS02805	COG0210	DNA helicase
THETH_RS02810	COG0497	DNA recombination
THETH_RS02815	COG0402	S-adenosylhomocysteine deaminase activity
THETH_RS02820	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THETH_RS02825	COG1242	4 iron, 4 sulfur cluster binding
THETH_RS02830	COG0840	transmembrane signaling receptor activity
THETH_RS02835	COG1618	nucleotide phosphatase activity, acting on free nucleotides
THETH_RS02840	COG0823	Involved in the tonB-independent uptake of proteins
THETH_RS02840	COG1506	peptidase
THETH_RS02840	COG4946	Tricorn protease homolog
THETH_RS02845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THETH_RS02880	COG0745	RESPONSE REGULATOR receiver
THETH_RS02885	COG5002	protein histidine kinase activity
THETH_RS02900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THETH_RS02925	COG2045	Belongs to the ComB family
THETH_RS02930	COG0126	phosphoglycerate kinase activity
THETH_RS02930	COG0149	triose-phosphate isomerase activity
THETH_RS02935	COG0126	phosphoglycerate kinase activity
THETH_RS02940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THETH_RS02945	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THETH_RS02950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THETH_RS02965	COG5002	protein histidine kinase activity
THETH_RS02970	COG3872	metal-dependent enzyme
THETH_RS02975	COG1078	dGTPase activity
THETH_RS02980	COG4555	ABC transporter
THETH_RS02995	COG0745	RESPONSE REGULATOR receiver
THETH_RS03000	COG2208	phosphoserine phosphatase activity
THETH_RS03005	COG0217	transcriptional regulatory protein
THETH_RS03015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
THETH_RS03020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THETH_RS03025	COG0564	pseudouridine synthase activity
THETH_RS03030	COG0587	DNA-directed DNA polymerase activity
THETH_RS03050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THETH_RS03055	COG0215	cysteine-tRNA ligase activity
THETH_RS03060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THETH_RS03070	COG0735	belongs to the Fur family
THETH_RS03075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THETH_RS03090	COG1811	Na channel or pump
THETH_RS03095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THETH_RS03105	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THETH_RS03110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THETH_RS03135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THETH_RS03140	COG1923	regulation of RNA biosynthetic process
THETH_RS03145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
THETH_RS03160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THETH_RS03165	COG0268	Binds directly to 16S ribosomal RNA
THETH_RS03175	COG0542	response to heat
THETH_RS03180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THETH_RS03185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
THETH_RS03190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
THETH_RS03195	COG0594	ribonuclease P activity
THETH_RS03200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
THETH_RS03205	COG0706	membrane insertase activity
THETH_RS03240	COG0411	ABC transporter
THETH_RS03250	COG1307	EDD domain protein, DegV family
THETH_RS03260	COG2199	diguanylate cyclase activity
THETH_RS03260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THETH_RS03265	COG1136	(ABC) transporter
THETH_RS03265	COG0577	efflux transmembrane transporter activity
THETH_RS03270	COG1136	(ABC) transporter
THETH_RS03275	COG1566	PFAM secretion protein HlyD family protein
THETH_RS03310	COG0528	UMP kinase activity
THETH_RS03315	COG0148	phosphopyruvate hydratase activity
THETH_RS03320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
THETH_RS03360	COG2252	PERMEase
THETH_RS03375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THETH_RS03375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THETH_RS03390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THETH_RS03395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
THETH_RS03405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THETH_RS03415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THETH_RS03435	COG0138	bifunctional purine biosynthesis protein purh
THETH_RS03440	COG1040	competence protein
THETH_RS03460	COG0601	transmembrane transport
THETH_RS03465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS03470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THETH_RS03475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THETH_RS03480	COG0772	Belongs to the SEDS family
THETH_RS03485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
THETH_RS03490	COG0800	Aldolase
THETH_RS03495	COG1546	Belongs to the CinA family
THETH_RS03495	COG1058	Belongs to the CinA family
THETH_RS03500	COG0643	Histidine kinase
THETH_RS03500	COG2198	Histidine kinase
THETH_RS03505	COG0835	chemotaxis
THETH_RS03510	COG2201	protein-glutamate methylesterase activity
THETH_RS03520	COG1338	Plays a role in the flagellum-specific transport system
THETH_RS03525	COG1987	bacterial-type flagellum assembly
THETH_RS03530	COG1684	flagellar biosynthetic protein fliR
THETH_RS03535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THETH_RS03540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THETH_RS03545	COG1419	protein localization to endoplasmic reticulum
THETH_RS03550	COG0455	bacterial-type flagellum organization
THETH_RS03560	COG1776	CheC inhibitor of MCP methylation
THETH_RS03565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
THETH_RS03590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THETH_RS03610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THETH_RS03615	COG0203	ribosomal protein L17
THETH_RS03620	COG0202	RNA polymerase activity
THETH_RS03625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THETH_RS03630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THETH_RS03635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THETH_RS03640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
THETH_RS03650	COG0563	adenylate kinase activity
THETH_RS03655	COG0201	protein transport
THETH_RS03660	COG0200	Binds to the 23S rRNA
THETH_RS03665	COG1841	ribosomal large subunit assembly
THETH_RS03670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THETH_RS03675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THETH_RS03680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THETH_RS03685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THETH_RS03690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THETH_RS03695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THETH_RS03700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THETH_RS03705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THETH_RS03710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THETH_RS03715	COG0255	Belongs to the universal ribosomal protein uL29 family
THETH_RS03720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THETH_RS03725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THETH_RS03730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
THETH_RS03735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THETH_RS03740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THETH_RS03745	COG0089	rRNA binding
THETH_RS03750	COG0088	Forms part of the polypeptide exit tunnel
THETH_RS03755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
THETH_RS03760	COG0051	transcription antitermination factor activity, RNA binding
THETH_RS03765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THETH_RS03770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THETH_RS03775	COG0049	tRNA binding
THETH_RS03780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THETH_RS03785	COG1323	Belongs to the UPF0348 family
THETH_RS03795	COG0322	excinuclease ABC activity
THETH_RS03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THETH_RS03805	COG1918	ferrous iron import across plasma membrane
THETH_RS03815	COG0306	phosphate transporter
THETH_RS03830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THETH_RS03835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
THETH_RS03860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THETH_RS03860	COG0072	phenylalanine-tRNA ligase activity
THETH_RS03865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THETH_RS03875	COG0571	ribonuclease III activity
THETH_RS03890	COG1774	PSP1 C-terminal conserved region
THETH_RS03900	COG1728	Protein conserved in bacteria
THETH_RS03905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THETH_RS03915	COG3956	TIGRFAM MazG family protein
THETH_RS03920	COG1392	Phosphate transport regulator
THETH_RS03925	COG1815	bacterial-type flagellum-dependent cell motility
THETH_RS03935	COG1677	Flagellar hook-basal body complex protein FliE
THETH_RS03970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
THETH_RS03975	COG0681	Belongs to the peptidase S26 family
THETH_RS03980	COG0335	large ribosomal subunit rRNA binding
THETH_RS03985	COG4752	Belongs to the RNA methyltransferase TrmD family
THETH_RS03990	COG0336	Belongs to the RNA methyltransferase TrmD family
THETH_RS03995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
THETH_RS04000	COG1837	Belongs to the UPF0109 family
THETH_RS04005	COG0228	four-way junction DNA binding
THETH_RS04010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THETH_RS04015	COG3876	Protein conserved in bacteria
THETH_RS04025	COG3842	ATPase activity
THETH_RS04030	COG0395	ABC-type sugar transport system, permease component
THETH_RS04055	COG4948	Mandelate Racemase Muconate Lactonizing
THETH_RS04060	COG0154	amidase activity
THETH_RS04070	COG1175	transmembrane transport
THETH_RS04075	COG0395	ABC-type sugar transport system, permease component
THETH_RS04085	COG0419	ATPase involved in DNA repair
THETH_RS04090	COG0420	3'-5' exonuclease activity
THETH_RS04095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THETH_RS04105	COG0037	tRNA processing
THETH_RS04110	COG0772	Belongs to the SEDS family
THETH_RS04120	COG0543	2 iron, 2 sulfur cluster binding
THETH_RS04125	COG0493	'glutamate synthase
THETH_RS04125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THETH_RS04135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THETH_RS04140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THETH_RS04150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THETH_RS04160	COG2078	PFAM AMMECR1 domain protein
THETH_RS04170	COG1477	protein flavinylation
THETH_RS04185	COG0424	maF-like protein
THETH_RS04190	COG2003	Belongs to the UPF0758 family
THETH_RS04200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THETH_RS04205	COG3404	Formiminotransferase-cyclodeaminase
THETH_RS04220	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
THETH_RS04230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THETH_RS04235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THETH_RS04240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
THETH_RS04245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THETH_RS04250	COG0193	aminoacyl-tRNA hydrolase activity
THETH_RS04260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
THETH_RS04265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
THETH_RS04270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THETH_RS04275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THETH_RS04285	COG0622	Phosphoesterase
THETH_RS04295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THETH_RS04300	COG1254	Belongs to the acylphosphatase family
THETH_RS04305	COG0517	IMP dehydrogenase activity
THETH_RS04305	COG0516	GMP reductase activity
THETH_RS04310	COG0751	glycine-tRNA ligase activity
THETH_RS04315	COG0752	glycyl-tRNA synthetase alpha subunit
THETH_RS04335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
THETH_RS04345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THETH_RS04350	COG0250	Participates in transcription elongation, termination and antitermination
THETH_RS04355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
THETH_RS04360	COG0081	regulation of translation
THETH_RS04365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THETH_RS04370	COG0222	ribosome binding
THETH_RS04375	COG0085	RNA polymerase activity
THETH_RS04380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THETH_RS04385	COG0116	Belongs to the methyltransferase superfamily
THETH_RS04390	COG0312	modulator of DNA gyrase
THETH_RS04395	COG0312	modulator of DNA gyrase
THETH_RS04400	COG1131	(ABC) transporter
THETH_RS04405	COG0592	DNA-directed DNA polymerase activity
THETH_RS04430	COG1454	alcohol dehydrogenase
THETH_RS04435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
THETH_RS04440	COG0436	Aminotransferase
THETH_RS04445	COG0728	peptidoglycan biosynthetic process
THETH_RS04450	COG1355	regulation of microtubule-based process
THETH_RS04485	COG1459	type II secretion system
THETH_RS04490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
THETH_RS04525	COG0793	Belongs to the peptidase S41A family
THETH_RS04530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
THETH_RS04545	COG0572	uridine kinase
THETH_RS04560	COG4948	Mandelate Racemase Muconate Lactonizing
THETH_RS04565	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THETH_RS04570	COG1104	cysteine desulfurase activity
THETH_RS04585	COG0822	iron-sulfur transferase activity
THETH_RS04595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THETH_RS04600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THETH_RS04605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THETH_RS04620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THETH_RS04620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THETH_RS04625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THETH_RS04625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THETH_RS04635	COG0124	histidyl-tRNA synthetase
THETH_RS04655	COG1595	DNA-templated transcription, initiation
THETH_RS04665	COG2264	protein methyltransferase activity
THETH_RS04670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THETH_RS04675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
THETH_RS04680	COG1476	TRANSCRIPTIONal
THETH_RS04690	COG1013	pyruvate-flavodoxin oxidoreductase activity
THETH_RS04705	COG2201	protein-glutamate methylesterase activity
THETH_RS04710	COG0739	heme binding
THETH_RS04720	COG0557	exoribonuclease II activity
THETH_RS04730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THETH_RS04740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THETH_RS04750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THETH_RS04755	COG0154	amidase activity
THETH_RS04765	COG0482	sulfurtransferase activity
THETH_RS04775	COG0425	Belongs to the sulfur carrier protein TusA family
THETH_RS04780	COG2391	methyltransferase activity
THETH_RS04800	COG0425	Belongs to the sulfur carrier protein TusA family
THETH_RS04820	COG0747	negative chemotaxis
THETH_RS04825	COG0601	transmembrane transport
THETH_RS04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS04835	COG0444	Belongs to the ABC transporter superfamily
THETH_RS04840	COG4608	Belongs to the ABC transporter superfamily
THETH_RS04865	COG1131	(ABC) transporter
THETH_RS04870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
THETH_RS04875	COG2176	DNA-directed DNA polymerase activity
THETH_RS04880	COG0668	transmembrane transport
THETH_RS04890	COG1639	'signal transduction protein
THETH_RS04895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THETH_RS04900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THETH_RS04910	COG0280	phosphate acetyltransferase
THETH_RS04930	COG1904	glucuronate isomerase
THETH_RS04940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
THETH_RS04945	COG0295	cytidine deaminase activity
THETH_RS04950	COG4535	Mg2 and Co2 transporter CorC
THETH_RS04955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THETH_RS04960	COG1228	amidohydrolase
THETH_RS04975	COG3842	ATPase activity
THETH_RS04980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
THETH_RS04985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
THETH_RS04990	COG1120	ATPase activity
THETH_RS05020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
THETH_RS05025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
THETH_RS05040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THETH_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS05060	COG1070	Carbohydrate kinase
THETH_RS05070	COG1737	Transcriptional regulator
THETH_RS05075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THETH_RS05080	COG0673	inositol 2-dehydrogenase activity
THETH_RS05110	COG0640	Transcriptional regulator
THETH_RS05115	COG2217	Heavy metal translocating P-type atpase
THETH_RS05130	COG0697	spore germination
THETH_RS05155	COG0084	hydrolase, TatD family'
THETH_RS05175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
THETH_RS05180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
THETH_RS05185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THETH_RS05190	COG0131	Imidazoleglycerol-phosphate dehydratase
THETH_RS05195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
THETH_RS05200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
THETH_RS05205	COG0107	imidazoleglycerol-phosphate synthase activity
THETH_RS05210	COG0140	phosphoribosyl-ATP diphosphatase activity
THETH_RS05210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
THETH_RS05220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THETH_RS05225	COG0052	Belongs to the universal ribosomal protein uS2 family
THETH_RS05235	COG1067	ATP-dependent peptidase activity
THETH_RS05240	COG1214	PFAM Peptidase M22, glycoprotease
THETH_RS05250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THETH_RS05270	COG1110	DNA topoisomerase II activity
THETH_RS05285	COG0653	protein targeting
THETH_RS05305	COG0101	tRNA pseudouridine synthase activity
THETH_RS05310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THETH_RS05315	COG0242	peptide deformylase activity
THETH_RS05320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THETH_RS05330	COG0445	tRNA wobble uridine modification
THETH_RS05335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THETH_RS05340	COG1490	D-aminoacyl-tRNA deacylase activity
THETH_RS05345	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THETH_RS05355	COG2172	sigma factor antagonist activity
THETH_RS05360	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
THETH_RS05370	COG1482	cell wall glycoprotein biosynthetic process
THETH_RS05375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THETH_RS05380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
THETH_RS05395	COG1256	bacterial-type flagellum assembly
THETH_RS05395	COG4786	Flagellar basal body rod
THETH_RS05395	COG1256	bacterial-type flagellum assembly
THETH_RS05395	COG4786	Flagellar basal body rod
THETH_RS05400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THETH_RS05405	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
THETH_RS05410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
THETH_RS05415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THETH_RS05420	COG0792	nuclease activity
THETH_RS05425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THETH_RS05430	COG0564	pseudouridine synthase activity
THETH_RS05450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
THETH_RS05465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
THETH_RS05470	COG0750	zinc metalloprotease
THETH_RS05475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
THETH_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS05500	COG1349	DNA-binding transcription factor activity
THETH_RS05505	COG1063	alcohol dehydrogenase
THETH_RS05510	COG0673	inositol 2-dehydrogenase activity
THETH_RS05515	COG1402	creatininase
THETH_RS05525	COG1172	Belongs to the binding-protein-dependent transport system permease family
THETH_RS05560	COG1082	Xylose isomerase domain protein TIM barrel
THETH_RS05580	COG3842	ATPase activity
THETH_RS05585	COG2211	Major facilitator Superfamily
THETH_RS05600	COG1132	(ABC) transporter
THETH_RS05605	COG3328	transposase activity
THETH_RS05610	COG1234	tRNA 3'-trailer cleavage
THETH_RS05615	COG1082	Xylose isomerase domain protein TIM barrel
THETH_RS05620	COG1414	Transcriptional regulator
THETH_RS05625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THETH_RS05655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
THETH_RS05665	COG0395	ABC-type sugar transport system, permease component
THETH_RS05670	COG1175	transmembrane transport
THETH_RS05685	COG3534	alpha-L-arabinofuranosidase
THETH_RS05695	COG0395	ABC-type sugar transport system, permease component
THETH_RS05705	COG0395	ABC-type sugar transport system, permease component
THETH_RS05710	COG0395	ABC-type sugar transport system, permease component
THETH_RS05715	COG1175	transmembrane transport
THETH_RS05730	COG3507	Belongs to the glycosyl hydrolase 43 family
THETH_RS05735	COG2160	L-arabinose isomerase activity
THETH_RS05755	COG0765	amino acid transport
THETH_RS05765	COG0765	amino acid transport
THETH_RS05780	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
THETH_RS05785	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
THETH_RS05795	COG4658	electron transport chain
THETH_RS05810	COG0840	transmembrane signaling receptor activity
THETH_RS05820	COG0330	HflC and HflK could
THETH_RS05825	COG0546	phosphoglycolate phosphatase activity
THETH_RS05835	COG0604	alcohol dehydrogenase
THETH_RS05860	COG2197	response regulator
THETH_RS05900	COG1518	maintenance of DNA repeat elements
THETH_RS05905	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THETH_RS05975	COG1337	RAMP superfamily
THETH_RS06055	COG1307	EDD domain protein, DegV family
THETH_RS06065	COG0745	RESPONSE REGULATOR receiver
THETH_RS06070	COG5002	protein histidine kinase activity
THETH_RS06075	COG0492	ferredoxin-NADP+ reductase activity
THETH_RS06090	COG0330	HflC and HflK could
THETH_RS06100	COG1234	tRNA 3'-trailer cleavage
THETH_RS06105	COG0359	binds to the 23S rRNA
THETH_RS06120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THETH_RS06125	COG4869	propanediol catabolic process
THETH_RS06135	COG1473	amidohydrolase
THETH_RS06150	COG0840	transmembrane signaling receptor activity
THETH_RS06155	COG1957	nucleoside hydrolase
THETH_RS06160	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
THETH_RS06165	COG1744	ABC transporter substrate-binding protein PnrA-like
THETH_RS06170	COG3845	ABC transporter
THETH_RS06180	COG1079	Belongs to the binding-protein-dependent transport system permease family
THETH_RS06185	COG1187	pseudouridine synthase activity
THETH_RS06195	COG1744	ABC transporter substrate-binding protein PnrA-like
THETH_RS06200	COG3845	ABC transporter
THETH_RS06205	COG4603	Belongs to the binding-protein-dependent transport system permease family
THETH_RS06210	COG1079	Belongs to the binding-protein-dependent transport system permease family
THETH_RS06220	COG1193	negative regulation of DNA recombination
THETH_RS06230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THETH_RS06235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THETH_RS06240	COG0849	cell division
THETH_RS06250	COG0187	DNA topoisomerase II activity
THETH_RS06260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THETH_RS06265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THETH_RS06270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THETH_RS06270	COG0617	tRNA 3'-terminal CCA addition
THETH_RS06270	COG0517	IMP dehydrogenase activity
THETH_RS06280	COG1132	(ABC) transporter
THETH_RS06285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
THETH_RS06290	COG3829	transcription factor binding
THETH_RS06290	COG3290	protein histidine kinase activity
THETH_RS06295	COG1309	transcriptional regulator
THETH_RS06305	COG0427	acetyl-CoA hydrolase
THETH_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS06315	COG0183	Belongs to the thiolase family
THETH_RS06350	COG0596	Alpha beta hydrolase
THETH_RS06355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THETH_RS06360	COG2267	carboxylic ester hydrolase activity
THETH_RS06365	COG1324	tolerance protein
THETH_RS06370	COG0697	spore germination
THETH_RS06380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
THETH_RS06385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
THETH_RS06400	COG2359	stage V sporulation protein S
THETH_RS06435	COG3328	transposase activity
THETH_RS06440	COG0436	Aminotransferase
THETH_RS06445	COG1132	(ABC) transporter
THETH_RS06455	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
THETH_RS06460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
THETH_RS06465	COG0758	DNA mediated transformation
THETH_RS06465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THETH_RS06470	COG2878	Part of a membrane complex involved in electron transport
THETH_RS06475	COG4657	Part of a membrane complex involved in electron transport
THETH_RS06480	COG4660	Part of a membrane complex involved in electron transport
THETH_RS06490	COG4658	electron transport chain
THETH_RS06495	COG4656	Part of a membrane complex involved in electron transport
THETH_RS06500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
THETH_RS06515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THETH_RS06520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THETH_RS06525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THETH_RS06535	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
THETH_RS06545	COG0735	belongs to the Fur family
THETH_RS06550	COG0195	Participates in both transcription termination and antitermination
THETH_RS06555	COG0779	Required for maturation of 30S ribosomal subunits
THETH_RS06585	COG2313	pseudouridylate synthase activity
THETH_RS06620	COG2738	Putative neutral zinc metallopeptidase
THETH_RS06630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THETH_RS06635	COG1480	7TM receptor with intracellular HD hydrolase
THETH_RS06640	COG1702	phosphate starvation-inducible protein PhoH
THETH_RS06650	COG1032	radical SAM domain protein
THETH_RS06655	COG0673	inositol 2-dehydrogenase activity
THETH_RS06660	COG0747	negative chemotaxis
THETH_RS06670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS06680	COG0444	Belongs to the ABC transporter superfamily
THETH_RS06690	COG0444	Belongs to the ABC transporter superfamily
THETH_RS06695	COG4608	Belongs to the ABC transporter superfamily
THETH_RS06700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
THETH_RS06730	COG2362	D-Aminopeptidase
THETH_RS06770	COG3069	C4-dicarboxylate transmembrane transporter activity
THETH_RS06780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
THETH_RS06785	COG1921	L-seryl-tRNASec selenium transferase activity
THETH_RS06820	COG0736	holo-[acyl-carrier-protein] synthase activity
THETH_RS06830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
THETH_RS06835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
THETH_RS06840	COG0457	Tetratricopeptide repeat
THETH_RS06840	COG0463	Glycosyl transferase, family 2
THETH_RS06870	COG3328	transposase activity
THETH_RS06880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THETH_RS06895	COG1085	galactose-1-phosphate uridylyltransferase
THETH_RS06900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
THETH_RS06905	COG0840	transmembrane signaling receptor activity
THETH_RS06940	COG1070	Carbohydrate kinase
THETH_RS06945	COG0277	FAD linked oxidase domain protein
THETH_RS06950	COG2188	Transcriptional regulator
THETH_RS06955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THETH_RS06960	COG0351	phosphomethylpyrimidine kinase
THETH_RS06960	COG1992	Thiamine-phosphate synthase
THETH_RS06970	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THETH_RS06975	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
THETH_RS07000	COG0840	transmembrane signaling receptor activity
THETH_RS07015	COG0281	malic enzyme
THETH_RS07020	COG3875	lactate racemase activity
THETH_RS07025	COG2379	hydroxypyruvate reductase
THETH_RS07035	COG2610	gluconate transmembrane transporter activity
THETH_RS07045	COG1175	transmembrane transport
THETH_RS07050	COG0395	ABC-type sugar transport system, permease component
THETH_RS07120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THETH_RS07125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
THETH_RS07130	COG0537	adenosine 5'-monophosphoramidase activity
THETH_RS07150	COG1175	transmembrane transport
THETH_RS07190	COG0301	tRNA thio-modification
THETH_RS07270	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
THETH_RS07285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
THETH_RS07290	COG1278	Cold shock
THETH_RS07300	COG1486	melibiose metabolic process
THETH_RS07315	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THETH_RS07320	COG0492	ferredoxin-NADP+ reductase activity
THETH_RS07325	COG1335	isochorismatase
THETH_RS07335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THETH_RS07340	COG0235	Class ii aldolase
THETH_RS07350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
THETH_RS07380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THETH_RS07400	COG0360	Binds together with S18 to 16S ribosomal RNA
THETH_RS07405	COG0629	single-stranded DNA binding
THETH_RS07410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THETH_RS07430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THETH_RS07455	COG0383	alpha-mannosidase activity
THETH_RS07460	COG1609	Transcriptional regulator
THETH_RS07465	COG1653	transport
THETH_RS07480	COG3842	ATPase activity
THETH_RS07500	COG0438	transferase activity, transferring glycosyl groups
THETH_RS07535	COG0840	transmembrane signaling receptor activity
THETH_RS07540	COG0667	Aldo Keto reductase
THETH_RS07560	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
THETH_RS07565	COG0733	neurotransmitter:sodium symporter activity
THETH_RS07580	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
THETH_RS07585	COG1940	carbohydrate kinase activity
THETH_RS07590	COG1653	transport
THETH_RS07595	COG1175	transmembrane transport
THETH_RS07600	COG0395	ABC-type sugar transport system, permease component
THETH_RS07620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THETH_RS07625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
THETH_RS07635	COG1181	Belongs to the D-alanine--D-alanine ligase family
THETH_RS07655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THETH_RS07660	COG0039	L-malate dehydrogenase activity
THETH_RS07680	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THETH_RS07685	COG0346	lactoylglutathione lyase activity
THETH_RS07695	COG2111	Na H antiporter
THETH_RS07695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THETH_RS07705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THETH_RS07725	COG2111	Na H antiporter
THETH_RS07730	COG1006	Multisubunit Na H antiporter MnhC subunit
THETH_RS07735	COG1863	multisubunit Na H antiporter MnhE subunit
THETH_RS07740	COG0651	ATP synthesis coupled electron transport
THETH_RS07745	COG1966	Carbon starvation protein
THETH_RS07755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THETH_RS07760	COG1121	(ABC) transporter
THETH_RS07765	COG0803	Belongs to the bacterial solute-binding protein 9 family
THETH_RS07775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THETH_RS07780	COG0137	argininosuccinate synthase activity
THETH_RS07785	COG0165	Argininosuccinate lyase
THETH_RS07790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
THETH_RS07795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
THETH_RS07800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THETH_RS07805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THETH_RS07810	COG0505	Belongs to the CarA family
THETH_RS07815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THETH_RS07820	COG1609	Transcriptional regulator
THETH_RS07830	COG1175	transmembrane transport
THETH_RS07835	COG0395	ABC-type sugar transport system, permease component
THETH_RS07840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
THETH_RS07845	COG1554	hydrolase, family 65, central catalytic
THETH_RS07860	COG1609	Transcriptional regulator
THETH_RS07875	COG0395	ABC-type sugar transport system, permease component
THETH_RS07885	COG4946	Tricorn protease homolog
THETH_RS07885	COG1506	peptidase
THETH_RS07885	COG0823	Involved in the tonB-independent uptake of proteins
THETH_RS07890	COG2239	Acts as a magnesium transporter
THETH_RS07895	COG0009	L-threonylcarbamoyladenylate synthase
THETH_RS07930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
THETH_RS07935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
THETH_RS07940	COG0180	Tryptophanyl-tRNA synthetase
THETH_RS07945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THETH_RS07950	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THETH_RS07955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THETH_RS07965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THETH_RS07970	COG0006	proline dipeptidase activity
THETH_RS07975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THETH_RS07980	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THETH_RS07990	COG2033	superoxide reductase activity
THETH_RS07995	COG0840	transmembrane signaling receptor activity
THETH_RS08005	COG0737	Belongs to the 5'-nucleotidase family
THETH_RS08020	COG0714	Associated with various cellular activities
THETH_RS08035	COG0306	phosphate transporter
THETH_RS08045	COG1785	Belongs to the alkaline phosphatase family
THETH_RS08060	COG2361	Protein of unknown function DUF86
THETH_RS08075	COG1486	melibiose metabolic process
THETH_RS08080	COG0534	Mate efflux family protein
THETH_RS08115	COG0438	transferase activity, transferring glycosyl groups
THETH_RS08140	COG0438	transferase activity, transferring glycosyl groups
THETH_RS08145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
THETH_RS08170	COG2226	methyltransferase
THETH_RS08190	COG3842	ATPase activity
THETH_RS08195	COG0463	Glycosyl transferase, family 2
THETH_RS08205	COG0438	transferase activity, transferring glycosyl groups
THETH_RS08225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THETH_RS08230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THETH_RS08235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THETH_RS08235	COG1116	anion transmembrane transporter activity
THETH_RS08240	COG3693	PFAM glycoside hydrolase, family 10
THETH_RS08245	COG3693	PFAM glycoside hydrolase, family 10
THETH_RS08250	COG3250	beta-galactosidase activity
THETH_RS08255	COG3328	transposase activity
THETH_RS08270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THETH_RS08270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THETH_RS08295	COG3328	transposase activity
THETH_RS08315	COG0785	Cytochrome C biogenesis protein
THETH_RS08325	COG0517	IMP dehydrogenase activity
THETH_RS08345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
THETH_RS08350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THETH_RS08355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THETH_RS08365	COG1879	ABC-type sugar transport system periplasmic component
THETH_RS08370	COG1082	Xylose isomerase domain protein TIM barrel
THETH_RS08385	COG3852	Histidine kinase
THETH_RS08395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THETH_RS08405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THETH_RS08415	COG1706	bacterial-type flagellum-dependent cell motility
THETH_RS08420	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
THETH_RS08435	COG4786	Flagellar basal body rod
THETH_RS08440	COG1077	Cell shape determining protein MreB Mrl
THETH_RS08450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
THETH_RS08450	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
THETH_RS08455	COG0477	Major facilitator Superfamily
THETH_RS08460	COG3314	Sporulation integral membrane protein YlbJ
THETH_RS08465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
THETH_RS08500	COG1518	maintenance of DNA repeat elements
THETH_RS08505	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THETH_RS08550	COG0601	transmembrane transport
THETH_RS08560	COG4608	Belongs to the ABC transporter superfamily
THETH_RS08565	COG4608	Belongs to the ABC transporter superfamily
THETH_RS08575	COG1472	Belongs to the glycosyl hydrolase 3 family
THETH_RS08590	COG0357	Ribosomal RNA small subunit methyltransferase G
THETH_RS08595	COG0095	Lipoate-protein ligase
THETH_RS08600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THETH_RS08625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THETH_RS08630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
THETH_RS08650	COG0697	spore germination
THETH_RS08660	COG2199	diguanylate cyclase activity
THETH_RS08660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THETH_RS08670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THETH_RS08675	COG0174	glutamine synthetase
THETH_RS08680	COG0459	protein refolding
THETH_RS08685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THETH_RS08700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THETH_RS08705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
THETH_RS08715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
THETH_RS08720	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
THETH_RS08730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
THETH_RS08740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
THETH_RS08755	COG1077	Cell shape determining protein MreB Mrl
THETH_RS08810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
THETH_RS08815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THETH_RS08830	COG1131	(ABC) transporter
THETH_RS08840	COG2186	Transcriptional regulator
THETH_RS08845	COG1501	Belongs to the glycosyl hydrolase 31 family
THETH_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
THETH_RS08860	COG2721	sulfolactate sulfo-lyase activity
THETH_RS08865	COG2721	sulfolactate sulfo-lyase activity
THETH_RS08870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THETH_RS08880	COG1175	transmembrane transport
THETH_RS08890	COG2211	Major facilitator Superfamily
THETH_RS08900	COG1181	Belongs to the D-alanine--D-alanine ligase family
THETH_RS08915	COG3864	Putative metallopeptidase domain
THETH_RS08925	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THETH_RS08935	COG1162	GTPase activity
THETH_RS08940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THETH_RS08945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THETH_RS08950	COG0495	leucyl-tRNA aminoacylation
THETH_RS08960	COG0233	cytoplasmic translational termination
THETH_RS08965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
THETH_RS08970	COG0575	Belongs to the CDS family
THETH_RS08975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THETH_RS08985	COG0601	transmembrane transport
THETH_RS08990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS08995	COG0444	Belongs to the ABC transporter superfamily
THETH_RS09000	COG4608	Belongs to the ABC transporter superfamily
THETH_RS09040	COG1582	Flagellar protein (FlbD)
THETH_RS09050	COG1360	Flagellar Motor Protein
THETH_RS09060	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THETH_RS09065	COG1776	CheC inhibitor of MCP methylation
THETH_RS09065	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THETH_RS09090	COG0438	transferase activity, transferring glycosyl groups
THETH_RS09095	COG0395	ABC-type sugar transport system, permease component
THETH_RS09100	COG1175	transmembrane transport
THETH_RS09110	COG0484	heat shock protein binding
THETH_RS09115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THETH_RS09120	COG1420	regulation of RNA biosynthetic process
THETH_RS09125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
THETH_RS09130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THETH_RS09135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THETH_RS09145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THETH_RS09155	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
THETH_RS09170	COG1543	Belongs to the glycosyl hydrolase 57 family
THETH_RS09175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THETH_RS09180	COG1144	Oxidoreductase
THETH_RS09185	COG0674	pyruvate-flavodoxin oxidoreductase activity
THETH_RS09190	COG1013	pyruvate-flavodoxin oxidoreductase activity
THETH_RS09195	COG1335	isochorismatase
THETH_RS09205	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
THETH_RS09210	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
THETH_RS09220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THETH_RS09225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THETH_RS09235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THETH_RS09240	COG3426	butyrate kinase activity
THETH_RS09245	COG0280	phosphate acetyltransferase
THETH_RS09250	COG3426	butyrate kinase activity
THETH_RS09265	COG0674	pyruvate-flavodoxin oxidoreductase activity
THETH_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
THETH_RS09285	COG3234	Protein of unknown function (DUF1175)
THETH_RS09295	COG2373	Large extracellular alpha-helical protein
THETH_RS09300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
THETH_RS09305	COG0667	Aldo Keto reductase
THETH_RS09320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
THETH_RS09325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THETH_RS09335	COG0483	inositol monophosphate 1-phosphatase activity
THETH_RS09345	COG0662	Cupin 2, conserved barrel domain protein
THETH_RS09355	COG5001	Diguanylate cyclase
THETH_RS09355	COG5002	protein histidine kinase activity
THETH_RS09355	COG3447	MASE1 domain protein
THETH_RS09370	COG0018	arginyl-trna synthetase
THETH_RS09380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
THETH_RS09385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THETH_RS09390	COG0778	Nitroreductase
THETH_RS09395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THETH_RS09410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THETH_RS09415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THETH_RS09420	COG1196	nuclear chromosome segregation
THETH_RS09430	COG1704	LemA family
THETH_RS09435	COG0501	Belongs to the peptidase M48B family
THETH_RS09440	COG0606	chelatase, subunit chli
THETH_RS09450	COG0012	GTP binding
THETH_RS09460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THETH_RS09460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THETH_RS09470	COG0406	alpha-ribazole phosphatase activity
THETH_RS09475	COG0469	pyruvate kinase activity
THETH_RS09480	COG0205	6-phosphofructokinase activity
THETH_RS09490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
THETH_RS09495	COG0509	glycine decarboxylation via glycine cleavage system
THETH_RS09500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THETH_RS09505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THETH_RS09520	COG0205	6-phosphofructokinase activity
THETH_RS09525	COG2171	N-acyltransferase activity
THETH_RS09530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THETH_RS09535	COG1473	amidohydrolase
THETH_RS09540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THETH_RS09550	COG1760	l-serine dehydratase
THETH_RS09620	COG1609	Transcriptional regulator
THETH_RS09630	COG1129	ABC transporter
THETH_RS09645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THETH_RS09650	COG0543	2 iron, 2 sulfur cluster binding
THETH_RS09655	COG0167	dihydroorotate dehydrogenase activity
THETH_RS09660	COG0284	orotidine-5'-phosphate decarboxylase activity
THETH_RS09665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
THETH_RS09675	COG0572	uridine kinase
THETH_RS09685	COG0297	glycogen (starch) synthase activity
THETH_RS09695	COG2359	stage V sporulation protein S
THETH_RS09710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THETH_RS09715	COG1185	polyribonucleotide nucleotidyltransferase activity
THETH_RS09720	COG0612	Peptidase, M16
THETH_RS09735	COG1610	YqeY-like protein
THETH_RS09740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THETH_RS09745	COG0776	regulation of translation
THETH_RS09755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THETH_RS09755	COG0574	Belongs to the PEP-utilizing enzyme family
THETH_RS09760	COG2813	Specifically methylates the guanine in position
THETH_RS09765	COG1122	ATPase activity
THETH_RS09770	COG1122	ATPase activity
THETH_RS09785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THETH_RS09790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THETH_RS09795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THETH_RS09805	COG4120	Belongs to the binding-protein-dependent transport system permease family
THETH_RS09815	COG0019	diaminopimelate decarboxylase activity
THETH_RS09820	COG0393	Putative heavy-metal-binding
THETH_RS09850	COG0312	modulator of DNA gyrase
THETH_RS09865	COG0037	tRNA processing
THETH_RS09870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THETH_RS09885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THETH_RS09890	COG0358	DNA primase activity
THETH_RS09900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THETH_RS09905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THETH_RS09915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
THETH_RS09935	COG0525	valine-tRNA ligase activity
THETH_RS09940	COG0285	dihydrofolate synthase activity
THETH_RS09945	COG0632	four-way junction helicase activity
THETH_RS09960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THETH_RS09970	COG1196	nuclear chromosome segregation
THETH_RS09975	COG0494	nUDIX hydrolase
THETH_RS09985	COG1516	flagellar protein fliS
THETH_RS10000	COG0768	penicillin binding
THETH_RS10025	COG4608	Belongs to the ABC transporter superfamily
THETH_RS10030	COG0444	Belongs to the ABC transporter superfamily
THETH_RS10035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THETH_RS10040	COG0601	transmembrane transport
THETH_RS10050	COG1063	alcohol dehydrogenase
THETH_RS10055	COG0156	8-amino-7-oxononanoate synthase activity
THETH_RS10060	COG1461	Dihydroxyacetone kinase
THETH_RS10070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
THETH_RS10075	COG1722	exodeoxyribonuclease VII activity
THETH_RS10080	COG1570	exodeoxyribonuclease VII activity
THETH_RS10115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
THETH_RS10120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THETH_RS10125	COG0504	CTP synthase activity
THETH_RS10135	COG1418	mRNA catabolic process
THETH_RS10140	COG2137	regulation of response to DNA damage stimulus
THETH_RS10145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THETH_RS10150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
THETH_RS10155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
THETH_RS10160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THETH_RS10180	COG1428	Deoxynucleoside kinase
THETH_RS10185	COG0483	inositol monophosphate 1-phosphatase activity
THETH_RS10190	COG0556	nucleotide-excision repair
THETH_RS10200	COG1141	Ferredoxin
THETH_RS10220	COG3383	formate dehydrogenase (NAD+) activity
THETH_RS10225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
THETH_RS10230	COG2116	formate transmembrane transporter activity
THETH_RS10235	COG2116	formate transmembrane transporter activity
THETH_RS10255	COG2267	carboxylic ester hydrolase activity
THETH_RS10260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THETH_RS10275	COG0395	ABC-type sugar transport system, permease component
THETH_RS10285	COG2199	diguanylate cyclase activity
THETH_RS10300	COG0561	phosphatase activity
THETH_RS10330	COG0493	'glutamate synthase
THETH_RS10330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THETH_RS10335	COG0415	Belongs to the DNA photolyase family
THETH_RS10350	COG0456	acetyltransferase
THETH_RS10350	COG1214	PFAM Peptidase M22, glycoprotease
THETH_RS10400	COG0840	transmembrane signaling receptor activity