locus-tag	class	description
PB01_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PB01_RS00010	COG0592	DNA-directed DNA polymerase activity
PB01_RS00015	COG2501	S4 domain
PB01_RS00025	COG0187	DNA topoisomerase II activity
PB01_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PB01_RS00055	COG0386	Belongs to the glutathione peroxidase family
PB01_RS00060	COG0516	GMP reductase activity
PB01_RS00060	COG0517	IMP dehydrogenase activity
PB01_RS00070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB01_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PB01_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PB01_RS00090	COG0590	tRNA wobble adenosine to inosine editing
PB01_RS00095	COG1388	LysM domain
PB01_RS00095	COG3858	chitin binding
PB01_RS00100	COG1428	Deoxynucleoside kinase
PB01_RS00105	COG1428	Deoxynucleoside kinase
PB01_RS00120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PB01_RS00130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PB01_RS00160	COG1982	Orn Lys Arg decarboxylase major
PB01_RS00165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PB01_RS00170	COG3870	Protein conserved in bacteria
PB01_RS00175	COG1728	Protein conserved in bacteria
PB01_RS00180	COG0470	DNA polymerase III
PB01_RS00185	COG1774	PSP1 C-terminal conserved region
PB01_RS00190	COG4467	Involved in initiation control of chromosome replication
PB01_RS00195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PB01_RS00205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PB01_RS00210	COG2002	toxin-antitoxin pair type II binding
PB01_RS00220	COG0084	hydrolase, TatD family'
PB01_RS00225	COG3583	domain protein
PB01_RS00225	COG3584	3D domain protein
PB01_RS00240	COG4466	Protein conserved in bacteria
PB01_RS00250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PB01_RS00255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PB01_RS00260	COG0251	oxidation-reduction process
PB01_RS00285	COG0193	aminoacyl-tRNA hydrolase activity
PB01_RS00295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PB01_RS00300	COG2002	toxin-antitoxin pair type II binding
PB01_RS00305	COG2244	polysaccharide biosynthetic process
PB01_RS00310	COG3956	TIGRFAM MazG family protein
PB01_RS00315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PB01_RS00335	COG1098	S1 RNA binding domain
PB01_RS00340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB01_RS00345	COG0765	amino acid transport
PB01_RS00350	COG1126	abc transporter atp-binding protein
PB01_RS00375	COG2208	phosphoserine phosphatase activity
PB01_RS00385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PB01_RS00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PB01_RS00400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PB01_RS00405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PB01_RS00410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PB01_RS00415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PB01_RS00420	COG0512	Glutamine amidotransferase of anthranilate synthase
PB01_RS00425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PB01_RS00430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PB01_RS00435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PB01_RS00440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PB01_RS00445	COG1396	sequence-specific DNA binding
PB01_RS00550	COG0745	RESPONSE REGULATOR receiver
PB01_RS00555	COG5002	protein histidine kinase activity
PB01_RS00580	COG1131	(ABC) transporter
PB01_RS00585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PB01_RS00600	COG0702	epimerase
PB01_RS00605	COG1408	metallophosphoesterase
PB01_RS00615	COG2197	response regulator
PB01_RS00620	COG4585	Histidine kinase
PB01_RS00625	COG3239	Fatty acid desaturase
PB01_RS00630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PB01_RS00635	COG0420	3'-5' exonuclease activity
PB01_RS00640	COG0419	ATPase involved in DNA repair
PB01_RS00645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB01_RS00650	COG1116	anion transmembrane transporter activity
PB01_RS00660	COG1671	Belongs to the UPF0178 family
PB01_RS00665	COG0584	glycerophosphoryl diester phosphodiesterase
PB01_RS00670	COG1054	Belongs to the UPF0176 family
PB01_RS00725	COG2188	Transcriptional regulator
PB01_RS00735	COG0393	Putative heavy-metal-binding
PB01_RS00745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PB01_RS00750	COG5002	protein histidine kinase activity
PB01_RS00755	COG0745	RESPONSE REGULATOR receiver
PB01_RS00770	COG1473	amidohydrolase
PB01_RS00775	COG1288	antiporter activity
PB01_RS00780	COG1473	amidohydrolase
PB01_RS00785	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS00795	COG0583	DNA-binding transcription factor activity
PB01_RS00800	COG4895	conserved protein (DUF2196)
PB01_RS00805	COG1473	amidohydrolase
PB01_RS00810	COG1757	Na H antiporter
PB01_RS00840	COG0157	Belongs to the NadC ModD family
PB01_RS00845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PB01_RS00850	COG1104	cysteine desulfurase activity
PB01_RS00855	COG1827	regulation of RNA biosynthetic process
PB01_RS00865	COG0840	transmembrane signaling receptor activity
PB01_RS00875	COG2076	Multidrug Resistance protein
PB01_RS00880	COG2076	Multidrug Resistance protein
PB01_RS00890	COG4978	Transcriptional regulator
PB01_RS00890	COG0789	Transcriptional regulator
PB01_RS00895	COG2814	Major facilitator Superfamily
PB01_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS00925	COG1268	BioY protein
PB01_RS00930	COG0318	PFAM AMP-dependent synthetase and ligase
PB01_RS00935	COG0183	Belongs to the thiolase family
PB01_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS00960	COG1122	ATPase activity
PB01_RS00965	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PB01_RS00980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PB01_RS00990	COG0514	ATP-dependent DNA helicase (RecQ)
PB01_RS01010	COG0628	permease
PB01_RS01025	COG1268	BioY protein
PB01_RS01045	COG0281	malic enzyme
PB01_RS01055	COG0697	spore germination
PB01_RS01070	COG1714	RDD family
PB01_RS01095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PB01_RS01105	COG0460	homoserine dehydrogenase
PB01_RS01115	COG0166	Belongs to the GPI family
PB01_RS01120	COG0697	spore germination
PB01_RS01135	COG5002	protein histidine kinase activity
PB01_RS01150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PB01_RS01150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PB01_RS01160	COG2197	response regulator
PB01_RS01185	COG1408	metallophosphoesterase
PB01_RS01190	COG0586	Pfam SNARE associated Golgi protein
PB01_RS01195	COG1968	undecaprenyl-diphosphatase activity
PB01_RS01200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PB01_RS01205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PB01_RS01220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PB01_RS01235	COG4176	ABC-type proline glycine betaine transport system permease component
PB01_RS01240	COG3448	diguanylate cyclase activity
PB01_RS01240	COG4175	Glycine betaine
PB01_RS01250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PB01_RS01260	COG1131	(ABC) transporter
PB01_RS01265	COG3559	Exporter of polyketide antibiotics
PB01_RS01280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB01_RS01285	COG2368	4-hydroxyphenylacetate
PB01_RS01290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PB01_RS01295	COG5002	protein histidine kinase activity
PB01_RS01310	COG2323	membrane
PB01_RS01315	COG2720	vancomycin resistance protein
PB01_RS01320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PB01_RS01335	COG0494	nUDIX hydrolase
PB01_RS01340	COG1525	nuclease
PB01_RS01400	COG0583	DNA-binding transcription factor activity
PB01_RS01405	COG1288	antiporter activity
PB01_RS01410	COG1473	amidohydrolase
PB01_RS01415	COG3706	GGDEF domain
PB01_RS01425	COG1609	Transcriptional regulator
PB01_RS01435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PB01_RS01440	COG1129	ABC transporter
PB01_RS01445	COG1122	ATPase activity
PB01_RS01455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB01_RS01490	COG0579	oxidoreductase
PB01_RS01495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PB01_RS01505	COG0720	synthase
PB01_RS01520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PB01_RS01525	COG3507	Belongs to the glycosyl hydrolase 43 family
PB01_RS01535	COG1653	transport
PB01_RS01550	COG5578	integral membrane protein
PB01_RS01555	COG2115	Belongs to the xylose isomerase family
PB01_RS01560	COG1070	Carbohydrate kinase
PB01_RS01565	COG0667	Aldo Keto reductase
PB01_RS01585	COG0656	L-ascorbic acid biosynthetic process
PB01_RS01635	COG1473	amidohydrolase
PB01_RS01640	COG0444	Belongs to the ABC transporter superfamily
PB01_RS01645	COG4608	Belongs to the ABC transporter superfamily
PB01_RS01650	COG0601	transmembrane transport
PB01_RS01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS01660	COG0747	negative chemotaxis
PB01_RS01665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PB01_RS01680	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS01685	COG0406	alpha-ribazole phosphatase activity
PB01_RS01690	COG3584	3D domain protein
PB01_RS01690	COG1388	LysM domain
PB01_RS01710	COG2968	Membrane
PB01_RS01740	COG0701	Predicted permease
PB01_RS01745	COG3689	TIGRFAM TIGR03943 family protein
PB01_RS01750	COG0523	cobalamin synthesis protein
PB01_RS01770	COG0628	permease
PB01_RS01775	COG0709	Synthesizes selenophosphate from selenide and ATP
PB01_RS01780	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PB01_RS01785	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS01795	COG3340	Belongs to the peptidase S51 family
PB01_RS01810	COG0697	spore germination
PB01_RS01815	COG1937	Protein conserved in bacteria
PB01_RS01825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB01_RS01825	COG0425	Belongs to the sulfur carrier protein TusA family
PB01_RS01830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB01_RS01830	COG0425	Belongs to the sulfur carrier protein TusA family
PB01_RS01835	COG2210	Belongs to the sulfur carrier protein TusA family
PB01_RS01840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB01_RS01840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB01_RS01845	COG0425	Belongs to the sulfur carrier protein TusA family
PB01_RS01850	COG0730	response to heat
PB01_RS01865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PB01_RS01875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PB01_RS01880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PB01_RS01885	COG0791	NLP P60 protein
PB01_RS01930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB01_RS01940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB01_RS01960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PB01_RS01970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PB01_RS01980	COG3361	conserved protein (COG2071)
PB01_RS01985	COG2814	Major facilitator Superfamily
PB01_RS01995	COG5001	Diguanylate cyclase
PB01_RS01995	COG1716	ATPase activity
PB01_RS02040	COG3377	Domain of unknown function (DUF1805)
PB01_RS02045	COG0387	Pfam Sodium calcium exchanger
PB01_RS02080	COG1376	ErfK ybiS ycfS ynhG family protein
PB01_RS02085	COG2986	histidine ammonia-lyase
PB01_RS02090	COG1228	amidohydrolase
PB01_RS02095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PB01_RS02105	COG2766	serine protein kinase
PB01_RS02110	COG2718	Belongs to the UPF0229 family
PB01_RS02115	COG2719	SpoVR family
PB01_RS02125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PB01_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS02140	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PB01_RS02155	COG0531	amino acid
PB01_RS02160	COG1752	Esterase of the alpha-beta hydrolase superfamily
PB01_RS02165	COG3871	stress protein (general stress protein 26)
PB01_RS02175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PB01_RS02185	COG3711	transcriptional antiterminator
PB01_RS02200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB01_RS02205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PB01_RS02215	COG5002	protein histidine kinase activity
PB01_RS02220	COG3852	Histidine kinase
PB01_RS02230	COG1595	DNA-templated transcription, initiation
PB01_RS02260	COG0697	spore germination
PB01_RS02265	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS02270	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS02275	COG0747	negative chemotaxis
PB01_RS02280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS02285	COG0601	transmembrane transport
PB01_RS02290	COG0444	Belongs to the ABC transporter superfamily
PB01_RS02295	COG4608	Belongs to the ABC transporter superfamily
PB01_RS02300	COG3275	phosphorelay sensor kinase activity
PB01_RS02305	COG3279	Response regulator of the LytR AlgR family
PB01_RS02325	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS02330	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS02335	COG0747	negative chemotaxis
PB01_RS02340	COG0402	S-adenosylhomocysteine deaminase activity
PB01_RS02345	COG0784	Response regulator, receiver
PB01_RS02345	COG2205	protein histidine kinase activity
PB01_RS02350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PB01_RS02355	COG2208	phosphoserine phosphatase activity
PB01_RS02360	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS02365	COG1405	negative regulation of cell septum assembly
PB01_RS02365	COG3012	SEC-C Motif Domain Protein
PB01_RS02370	COG0840	transmembrane signaling receptor activity
PB01_RS02375	COG0392	lysyltransferase activity
PB01_RS02375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PB01_RS02405	COG2176	DNA-directed DNA polymerase activity
PB01_RS02435	COG0737	Belongs to the 5'-nucleotidase family
PB01_RS02455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PB01_RS02470	COG2226	methyltransferase
PB01_RS02485	COG2027	D-alanyl-D-alanine carboxypeptidase
PB01_RS02510	COG3546	catalase activity
PB01_RS02555	COG0784	Response regulator, receiver
PB01_RS02555	COG3437	response regulator, receiver
PB01_RS02580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PB01_RS02605	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS02615	COG1960	acyl-CoA dehydrogenase activity
PB01_RS02625	COG0726	polysaccharide deacetylase
PB01_RS02630	COG2966	Psort location CytoplasmicMembrane, score
PB01_RS02635	COG3610	response to peptide
PB01_RS02640	COG2203	Gaf domain
PB01_RS02640	COG4251	negative regulation of phosphorylation
PB01_RS02640	COG3706	GGDEF domain
PB01_RS02640	COG5001	Diguanylate cyclase
PB01_RS02645	COG0697	spore germination
PB01_RS02650	COG1132	(ABC) transporter
PB01_RS02655	COG1132	(ABC) transporter
PB01_RS02660	COG1214	PFAM Peptidase M22, glycoprotease
PB01_RS02660	COG0456	acetyltransferase
PB01_RS02675	COG0586	Pfam SNARE associated Golgi protein
PB01_RS02680	COG0584	glycerophosphoryl diester phosphodiesterase
PB01_RS02685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS02690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS02695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB01_RS02700	COG1120	ATPase activity
PB01_RS02705	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS02730	COG3706	GGDEF domain
PB01_RS02735	COG0778	Nitroreductase
PB01_RS02775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB01_RS02810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB01_RS02825	COG0488	(ABC) transporter
PB01_RS02840	COG0702	epimerase
PB01_RS02845	COG0431	NADPH-dependent FMN reductase
PB01_RS02855	COG1595	DNA-templated transcription, initiation
PB01_RS02865	COG2801	Transposase and inactivated derivatives
PB01_RS02875	COG4585	Histidine kinase
PB01_RS02880	COG2197	response regulator
PB01_RS02885	COG1131	(ABC) transporter
PB01_RS02900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PB01_RS02940	COG0501	Belongs to the peptidase M48B family
PB01_RS02950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PB01_RS02965	COG1937	Protein conserved in bacteria
PB01_RS02970	COG2608	mercury ion transmembrane transporter activity
PB01_RS02975	COG2217	Heavy metal translocating P-type atpase
PB01_RS02980	COG1388	LysM domain
PB01_RS02985	COG0671	phosphoesterase, PA-phosphatase related
PB01_RS02995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PB01_RS03000	COG2364	Membrane
PB01_RS03015	COG0156	8-amino-7-oxononanoate synthase activity
PB01_RS03025	COG3314	Sporulation integral membrane protein YlbJ
PB01_RS03030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PB01_RS03035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PB01_RS03070	COG2363	Small membrane protein
PB01_RS03080	COG3773	Cell wall hydrolase
PB01_RS03085	COG3253	May function as heme-dependent peroxidase
PB01_RS03090	COG0280	phosphate acetyltransferase
PB01_RS03110	COG1078	dGTPase activity
PB01_RS03115	COG3465	dGTPase activity
PB01_RS03130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PB01_RS03135	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PB01_RS03140	COG0010	Belongs to the arginase family
PB01_RS03150	COG0018	arginyl-trna synthetase
PB01_RS03160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB01_RS03165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS03170	COG1120	ATPase activity
PB01_RS03175	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PB01_RS03180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PB01_RS03190	COG1492	cobalamin metabolic process
PB01_RS03195	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PB01_RS03210	COG2096	Adenosyltransferase
PB01_RS03230	COG0247	lactate metabolic process
PB01_RS03230	COG2181	nitrate reductase activity
PB01_RS03235	COG0183	Belongs to the thiolase family
PB01_RS03240	COG1250	3-hydroxyacyl-CoA dehydrogenase
PB01_RS03245	COG1960	acyl-CoA dehydrogenase activity
PB01_RS03250	COG1960	acyl-CoA dehydrogenase activity
PB01_RS03255	COG3226	Transcriptional regulator
PB01_RS03260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PB01_RS03260	COG1703	isobutyryl-CoA mutase activity
PB01_RS03260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PB01_RS03265	COG3343	RNA polymerase activity
PB01_RS03270	COG0504	CTP synthase activity
PB01_RS03280	COG2204	response regulator
PB01_RS03285	COG0191	fructose-bisphosphate aldolase activity
PB01_RS03295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PB01_RS03300	COG1494	fructose-1,6-bisphosphatase
PB01_RS03305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PB01_RS03310	COG0254	rRNA binding
PB01_RS03315	COG1435	thymidine kinase activity
PB01_RS03320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PB01_RS03325	COG2890	protein-(glutamine-N5) methyltransferase activity
PB01_RS03335	COG0009	L-threonylcarbamoyladenylate synthase
PB01_RS03350	COG0840	transmembrane signaling receptor activity
PB01_RS03355	COG0698	ribose 5-phosphate isomerase
PB01_RS03360	COG4475	Protein of unknown function (DUF436)
PB01_RS03370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PB01_RS03410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PB01_RS03420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PB01_RS03425	COG4836	Membrane
PB01_RS03430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PB01_RS03440	COG2385	sporulation resulting in formation of a cellular spore
PB01_RS03450	COG1609	Transcriptional regulator
PB01_RS03455	COG1077	Cell shape determining protein MreB Mrl
PB01_RS03460	COG4786	Flagellar basal body rod
PB01_RS03465	COG4786	Flagellar basal body rod
PB01_RS03475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PB01_RS03490	COG0629	single-stranded DNA binding
PB01_RS03495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PB01_RS03500	COG4715	Zinc finger, swim domain protein
PB01_RS03520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PB01_RS03525	COG0793	Belongs to the peptidase S41A family
PB01_RS03545	COG4145	pantothenate transmembrane transporter activity
PB01_RS03550	COG0697	spore germination
PB01_RS03560	COG1191	sigma factor activity
PB01_RS03570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PB01_RS03575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PB01_RS03600	COG3620	sequence-specific DNA binding
PB01_RS03605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB01_RS03610	COG0765	amino acid transport
PB01_RS03615	COG1126	abc transporter atp-binding protein
PB01_RS03640	COG1682	transport, permease protein
PB01_RS03650	COG1216	Glycosyl transferase, family 2
PB01_RS03650	COG0438	transferase activity, transferring glycosyl groups
PB01_RS03675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PB01_RS03690	COG1091	dTDP-4-dehydrorhamnose reductase activity
PB01_RS03700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PB01_RS03705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PB01_RS03735	COG4585	Histidine kinase
PB01_RS03740	COG2197	response regulator
PB01_RS03745	COG1404	Belongs to the peptidase S8 family
PB01_RS03800	COG3944	biosynthesis protein
PB01_RS03805	COG0489	protein tyrosine kinase activity
PB01_RS03820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PB01_RS03825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PB01_RS03830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PB01_RS03870	COG0438	transferase activity, transferring glycosyl groups
PB01_RS03875	COG0438	transferase activity, transferring glycosyl groups
PB01_RS03925	COG1192	Involved in chromosome partitioning
PB01_RS03940	COG0477	Major facilitator Superfamily
PB01_RS03965	COG2972	Histidine kinase
PB01_RS03965	COG0745	RESPONSE REGULATOR receiver
PB01_RS03970	COG3279	Response regulator of the LytR AlgR family
PB01_RS03980	COG2801	Transposase and inactivated derivatives
PB01_RS03990	COG1609	Transcriptional regulator
PB01_RS04015	COG1122	ATPase activity
PB01_RS04020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB01_RS04030	COG2801	Transposase and inactivated derivatives
PB01_RS04045	COG0028	Belongs to the TPP enzyme family
PB01_RS04075	COG5002	protein histidine kinase activity
PB01_RS04080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PB01_RS04115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB01_RS04120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB01_RS04125	COG1447	Phosphotransferase system cellobiose-specific component IIA
PB01_RS04130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB01_RS04140	COG0737	Belongs to the 5'-nucleotidase family
PB01_RS04145	COG2356	endonuclease I
PB01_RS04170	COG1988	membrane-bound metal-dependent
PB01_RS04175	COG5002	protein histidine kinase activity
PB01_RS04195	COG1404	Belongs to the peptidase S8 family
PB01_RS04200	COG1404	Belongs to the peptidase S8 family
PB01_RS04225	COG1404	Belongs to the peptidase S8 family
PB01_RS04235	COG5002	protein histidine kinase activity
PB01_RS04240	COG2201	protein-glutamate methylesterase activity
PB01_RS04250	COG5492	domain, Protein
PB01_RS04260	COG2267	carboxylic ester hydrolase activity
PB01_RS04265	COG0666	response to abiotic stimulus
PB01_RS04270	COG0450	alkyl hydroperoxide reductase
PB01_RS04275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS04280	COG0590	tRNA wobble adenosine to inosine editing
PB01_RS04285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PB01_RS04290	COG0739	heme binding
PB01_RS04305	COG3118	belongs to the thioredoxin family
PB01_RS04310	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS04320	COG0668	transmembrane transport
PB01_RS04325	COG1309	transcriptional regulator
PB01_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS04340	COG1802	Transcriptional regulator
PB01_RS04345	COG0444	Belongs to the ABC transporter superfamily
PB01_RS04350	COG4608	Belongs to the ABC transporter superfamily
PB01_RS04355	COG0601	transmembrane transport
PB01_RS04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS04365	COG0747	negative chemotaxis
PB01_RS04410	COG2235	arginine
PB01_RS04420	COG0833	amino acid
PB01_RS04425	COG4187	Peptidase family M20/M25/M40
PB01_RS04430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PB01_RS04435	COG0791	NLP P60 protein
PB01_RS04435	COG1388	LysM domain
PB01_RS04440	COG3835	regulator
PB01_RS04445	COG1929	Belongs to the glycerate kinase type-1 family
PB01_RS04450	COG2610	gluconate transmembrane transporter activity
PB01_RS04465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PB01_RS04470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PB01_RS04480	COG0745	RESPONSE REGULATOR receiver
PB01_RS04485	COG5002	protein histidine kinase activity
PB01_RS04485	COG3850	Histidine kinase
PB01_RS04495	COG0506	proline dehydrogenase activity
PB01_RS04500	COG4948	Mandelate Racemase Muconate Lactonizing
PB01_RS04510	COG1473	amidohydrolase
PB01_RS04530	COG0436	Aminotransferase
PB01_RS04535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PB01_RS04540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PB01_RS04550	COG1984	allophanate hydrolase subunit 2
PB01_RS04555	COG1316	TRANSCRIPTIONal
PB01_RS04565	COG0653	protein targeting
PB01_RS04585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PB01_RS04600	COG0673	inositol 2-dehydrogenase activity
PB01_RS04620	COG0482	sulfurtransferase activity
PB01_RS04640	COG0297	glycogen (starch) synthase activity
PB01_RS04645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PB01_RS04655	COG1316	TRANSCRIPTIONal
PB01_RS04660	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB01_RS04670	COG2247	cell wall binding repeat
PB01_RS04670	COG2385	sporulation resulting in formation of a cellular spore
PB01_RS04675	COG2340	Cysteine-rich secretory protein family
PB01_RS04680	COG1739	Uncharacterized protein family UPF0029
PB01_RS04685	COG4585	Histidine kinase
PB01_RS04690	COG2197	response regulator
PB01_RS04705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PB01_RS04710	COG1040	competence protein
PB01_RS04720	COG2747	anti-sigma28 factor FlgM
PB01_RS04725	COG3418	PFAM FlgN family protein
PB01_RS04730	COG1256	bacterial-type flagellum assembly
PB01_RS04730	COG4786	Flagellar basal body rod
PB01_RS04735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PB01_RS04745	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PB01_RS04750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PB01_RS04760	COG1334	flagellar protein FlaG
PB01_RS04765	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PB01_RS04770	COG1516	flagellar protein fliS
PB01_RS04790	COG0791	NLP P60 protein
PB01_RS04790	COG1388	LysM domain
PB01_RS04795	COG0840	transmembrane signaling receptor activity
PB01_RS04805	COG0129	dihydroxy-acid dehydratase activity
PB01_RS04810	COG0028	Belongs to the TPP enzyme family
PB01_RS04815	COG0440	acetolactate synthase activity
PB01_RS04840	COG0066	3-isopropylmalate dehydratase activity
PB01_RS04845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PB01_RS04850	COG2514	catechol 2,3-dioxygenase activity
PB01_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS04860	COG0840	transmembrane signaling receptor activity
PB01_RS04865	COG0791	NLP P60 protein
PB01_RS04880	COG0653	protein targeting
PB01_RS04890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS04900	COG2884	Cell division ATP-binding protein ftsE
PB01_RS04905	COG2177	Part of the ABC transporter FtsEX involved in
PB01_RS04910	COG1196	nuclear chromosome segregation
PB01_RS04910	COG0741	lytic transglycosylase activity
PB01_RS04910	COG0739	heme binding
PB01_RS04915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS04920	COG3409	Peptidoglycan-binding domain 1 protein
PB01_RS04920	COG0793	Belongs to the peptidase S41A family
PB01_RS04925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB01_RS04930	COG4897	Protein conserved in bacteria
PB01_RS04940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PB01_RS04945	COG0398	Pfam SNARE associated Golgi protein
PB01_RS04960	COG2311	Membrane
PB01_RS04965	COG0179	Fumarylacetoacetate (FAA) hydrolase
PB01_RS04975	COG0366	Alpha amylase catalytic
PB01_RS04975	COG1874	Beta-galactosidase
PB01_RS04985	COG1307	EDD domain protein, DegV family
PB01_RS04990	COG0561	phosphatase activity
PB01_RS04995	COG1073	alpha beta
PB01_RS05000	COG2151	metal-sulfur cluster biosynthetic enzyme
PB01_RS05020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PB01_RS05025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PB01_RS05035	COG4608	Belongs to the ABC transporter superfamily
PB01_RS05040	COG0601	transmembrane transport
PB01_RS05045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS05050	COG0747	negative chemotaxis
PB01_RS05055	COG0180	Tryptophanyl-tRNA synthetase
PB01_RS05065	COG4166	transmembrane transport
PB01_RS05070	COG0601	transmembrane transport
PB01_RS05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS05080	COG0444	Belongs to the ABC transporter superfamily
PB01_RS05085	COG4608	Belongs to the ABC transporter superfamily
PB01_RS05095	COG1393	Belongs to the ArsC family
PB01_RS05100	COG4862	establishment of competence for transformation
PB01_RS05110	COG1164	Oligoendopeptidase f
PB01_RS05115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PB01_RS05120	COG2346	COG2346, Truncated hemoglobins
PB01_RS05125	COG1196	nuclear chromosome segregation
PB01_RS05125	COG0741	lytic transglycosylase activity
PB01_RS05125	COG0739	heme binding
PB01_RS05130	COG4116	CYTH
PB01_RS05140	COG2357	RelA SpoT domain protein
PB01_RS05150	COG0564	pseudouridine synthase activity
PB01_RS05155	COG2239	Acts as a magnesium transporter
PB01_RS05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PB01_RS05225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PB01_RS05235	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PB01_RS05240	COG2382	esterase
PB01_RS05245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PB01_RS05250	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS05255	COG1363	Peptidase, m42
PB01_RS05260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PB01_RS05270	COG0861	Integral membrane protein TerC family
PB01_RS05275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PB01_RS05285	COG5002	protein histidine kinase activity
PB01_RS05290	COG1846	Transcriptional regulator
PB01_RS05305	COG4873	Protein conserved in bacteria
PB01_RS05320	COG0714	Associated with various cellular activities
PB01_RS05335	COG2084	Dehydrogenase
PB01_RS05340	COG0784	Response regulator, receiver
PB01_RS05340	COG0835	chemotaxis
PB01_RS05350	COG3300	MHYT domain
PB01_RS05350	COG5001	Diguanylate cyclase
PB01_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS05360	COG0517	IMP dehydrogenase activity
PB01_RS05365	COG0583	DNA-binding transcription factor activity
PB01_RS05375	COG1131	(ABC) transporter
PB01_RS05390	COG0714	Associated with various cellular activities
PB01_RS05410	COG2814	Major facilitator Superfamily
PB01_RS05420	COG1177	transmembrane transport
PB01_RS05425	COG1176	ABC-type spermidine putrescine transport system, permease component I
PB01_RS05430	COG3842	ATPase activity
PB01_RS05435	COG1476	TRANSCRIPTIONal
PB01_RS05445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS05450	COG0569	domain protein
PB01_RS05455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PB01_RS05465	COG0561	phosphatase activity
PB01_RS05475	COG0242	peptide deformylase activity
PB01_RS05490	COG0022	dehydrogenase e1 component
PB01_RS05495	COG0508	dehydrogenase complex catalyzes the overall conversion of
PB01_RS05505	COG1309	transcriptional regulator
PB01_RS05510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB01_RS05520	COG1380	Effector of murein hydrolase LrgA
PB01_RS05525	COG1346	cytolysis
PB01_RS05530	COG1982	Orn Lys Arg decarboxylase major
PB01_RS05555	COG0483	inositol monophosphate 1-phosphatase activity
PB01_RS05565	COG1217	gtp-binding protein TYPA
PB01_RS05575	COG4896	Protein conserved in bacteria
PB01_RS05580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PB01_RS05590	COG0772	Belongs to the SEDS family
PB01_RS05595	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PB01_RS05625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PB01_RS05630	COG3336	cytochrome c oxidase
PB01_RS05640	COG0628	permease
PB01_RS05650	COG2340	Cysteine-rich secretory protein family
PB01_RS05660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PB01_RS05670	COG3679	Belongs to the UPF0342 family
PB01_RS05675	COG0584	glycerophosphoryl diester phosphodiesterase
PB01_RS05680	COG4471	UPF0298 protein
PB01_RS05695	COG0742	ribosomal rna small subunit methyltransferase
PB01_RS05700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PB01_RS05710	COG3480	Lon protease (S16) C-terminal proteolytic domain
PB01_RS05730	COG1024	Enoyl-CoA hydratase
PB01_RS05740	COG0439	Biotin carboxylase
PB01_RS05745	COG0511	ligase activity, forming carbon-carbon bonds
PB01_RS05750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PB01_RS05755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PB01_RS05770	COG2001	Belongs to the MraZ family
PB01_RS05785	COG0768	penicillin binding
PB01_RS05790	COG0768	penicillin binding
PB01_RS05795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PB01_RS05805	COG0772	Belongs to the SEDS family
PB01_RS05810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PB01_RS05815	COG3879	Bacterial protein of unknown function (DUF881)
PB01_RS05820	COG3879	Bacterial protein of unknown function (DUF881)
PB01_RS05825	COG3856	small basic protein
PB01_RS05830	COG0849	cell division
PB01_RS05835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PB01_RS05845	COG1191	sigma factor activity
PB01_RS05850	COG1191	sigma factor activity
PB01_RS05860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PB01_RS05865	COG1799	cell septum assembly
PB01_RS05870	COG0762	integral membrane protein
PB01_RS05875	COG2302	S4 RNA-binding domain
PB01_RS05880	COG3599	regulation of cell shape
PB01_RS05890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PB01_RS05895	COG0564	pseudouridine synthase activity
PB01_RS05900	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PB01_RS05910	COG0540	Belongs to the ATCase OTCase family
PB01_RS05935	COG0167	dihydroorotate dehydrogenase activity
PB01_RS05945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PB01_RS05950	COG0840	transmembrane signaling receptor activity
PB01_RS05965	COG1136	(ABC) transporter
PB01_RS05970	COG0577	efflux transmembrane transporter activity
PB01_RS05985	COG0596	Alpha beta hydrolase
PB01_RS05995	COG0583	DNA-binding transcription factor activity
PB01_RS06000	COG0583	DNA-binding transcription factor activity
PB01_RS06005	COG0384	phenazine biosynthesis protein PhzF
PB01_RS06020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB01_RS06025	COG0805	protein transport
PB01_RS06045	COG0745	RESPONSE REGULATOR receiver
PB01_RS06050	COG5002	protein histidine kinase activity
PB01_RS06070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PB01_RS06075	COG1132	(ABC) transporter
PB01_RS06085	COG5002	protein histidine kinase activity
PB01_RS06090	COG3152	Membrane
PB01_RS06095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PB01_RS06125	COG1115	amino acid carrier protein
PB01_RS06150	COG1533	DNA photolyase activity
PB01_RS06160	COG1496	oxidoreductase activity
PB01_RS06180	COG1115	amino acid carrier protein
PB01_RS06190	COG2169	Transcriptional regulator
PB01_RS06200	COG0583	DNA-binding transcription factor activity
PB01_RS06205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS06220	COG0840	transmembrane signaling receptor activity
PB01_RS06225	COG1649	PFAM Uncharacterised BCR, COG1649
PB01_RS06235	COG2814	Major facilitator Superfamily
PB01_RS06240	COG0791	NLP P60 protein
PB01_RS06240	COG1388	LysM domain
PB01_RS06330	COG1595	DNA-templated transcription, initiation
PB01_RS06340	COG1027	Aspartate ammonia-lyase
PB01_RS06355	COG0194	GDP metabolic process
PB01_RS06365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PB01_RS06370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PB01_RS06375	COG0242	peptide deformylase activity
PB01_RS06385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PB01_RS06385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PB01_RS06390	COG0631	protein serine/threonine phosphatase activity
PB01_RS06395	COG0515	serine threonine protein kinase
PB01_RS06395	COG2815	serine threonine protein kinase
PB01_RS06405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PB01_RS06420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PB01_RS06425	COG1302	Protein conserved in bacteria
PB01_RS06430	COG1461	Dihydroxyacetone kinase
PB01_RS06435	COG1760	l-serine dehydratase
PB01_RS06440	COG1760	l-serine dehydratase
PB01_RS06445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PB01_RS06450	COG1349	DNA-binding transcription factor activity
PB01_RS06460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PB01_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS06470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PB01_RS06480	COG1196	nuclear chromosome segregation
PB01_RS06485	COG0552	protein localization to endoplasmic reticulum
PB01_RS06495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PB01_RS06505	COG1837	Belongs to the UPF0109 family
PB01_RS06535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PB01_RS06545	COG2257	FlhB HrpN YscU SpaS Family
PB01_RS06550	COG0045	succinate-CoA ligase (ADP-forming) activity
PB01_RS06555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PB01_RS06565	COG0758	DNA mediated transformation
PB01_RS06570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PB01_RS06580	COG4974	Belongs to the 'phage' integrase family
PB01_RS06590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PB01_RS06600	COG1815	bacterial-type flagellum-dependent cell motility
PB01_RS06605	COG1558	bacterial-type flagellum-dependent cell motility
PB01_RS06610	COG1677	Flagellar hook-basal body complex protein FliE
PB01_RS06615	COG1766	The M ring may be actively involved in energy transduction
PB01_RS06620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PB01_RS06625	COG1317	bacterial-type flagellum organization
PB01_RS06630	COG1157	protein secretion by the type III secretion system
PB01_RS06635	COG2882	bacterial-type flagellum organization
PB01_RS06650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PB01_RS06660	COG4786	Flagellar basal body rod
PB01_RS06665	COG1582	Flagellar protein (FlbD)
PB01_RS06670	COG1580	Controls the rotational direction of flagella during chemotaxis
PB01_RS06675	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PB01_RS06680	COG1776	CheC inhibitor of MCP methylation
PB01_RS06680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PB01_RS06685	COG2201	protein-glutamate methylesterase activity
PB01_RS06690	COG3190	flagellar
PB01_RS06695	COG1338	Plays a role in the flagellum-specific transport system
PB01_RS06700	COG1987	bacterial-type flagellum assembly
PB01_RS06705	COG1684	flagellar biosynthetic protein fliR
PB01_RS06710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PB01_RS06715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PB01_RS06720	COG1419	protein localization to endoplasmic reticulum
PB01_RS06725	COG0455	bacterial-type flagellum organization
PB01_RS06730	COG2201	protein-glutamate methylesterase activity
PB01_RS06735	COG2198	Histidine kinase
PB01_RS06735	COG0643	Histidine kinase
PB01_RS06740	COG0835	chemotaxis
PB01_RS06745	COG1776	CheC inhibitor of MCP methylation
PB01_RS06750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PB01_RS06760	COG1191	sigma factor activity
PB01_RS06790	COG0233	cytoplasmic translational termination
PB01_RS06795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PB01_RS06800	COG4589	Belongs to the CDS family
PB01_RS06810	COG0750	zinc metalloprotease
PB01_RS06815	COG2176	DNA-directed DNA polymerase activity
PB01_RS06825	COG0195	Participates in both transcription termination and antitermination
PB01_RS06830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PB01_RS06835	COG1358	cellular component organization or biogenesis
PB01_RS06845	COG1550	Protein conserved in bacteria
PB01_RS06855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PB01_RS06860	COG0196	riboflavin kinase activity
PB01_RS06875	COG0612	Peptidase, M16
PB01_RS06890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PB01_RS06895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PB01_RS06905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PB01_RS06910	COG1674	ftsk spoiiie
PB01_RS06915	COG2188	Transcriptional regulator
PB01_RS06920	COG1744	ABC transporter substrate-binding protein PnrA-like
PB01_RS06925	COG3845	ABC transporter
PB01_RS06930	COG4603	Belongs to the binding-protein-dependent transport system permease family
PB01_RS06935	COG1079	Belongs to the binding-protein-dependent transport system permease family
PB01_RS06940	COG0612	Peptidase, M16
PB01_RS06945	COG0612	Peptidase, M16
PB01_RS06950	COG0300	oxidoreductase activity
PB01_RS06960	COG1426	Protein conserved in bacteria
PB01_RS06965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PB01_RS06985	COG1692	metallophosphoesterase
PB01_RS06990	COG2359	stage V sporulation protein S
PB01_RS06995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PB01_RS06995	COG0674	pyruvate-flavodoxin oxidoreductase activity
PB01_RS07000	COG1013	pyruvate-flavodoxin oxidoreductase activity
PB01_RS07005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PB01_RS07010	COG4550	Control of competence regulator ComK, YlbF/YmcA
PB01_RS07020	COG2211	Major facilitator Superfamily
PB01_RS07025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PB01_RS07030	COG2807	transmembrane transport
PB01_RS07035	COG1131	(ABC) transporter
PB01_RS07055	COG0363	glucosamine-6-phosphate deaminase activity
PB01_RS07070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PB01_RS07075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PB01_RS07095	COG1923	regulation of RNA biosynthetic process
PB01_RS07100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB01_RS07105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PB01_RS07110	COG0789	Transcriptional regulator
PB01_RS07115	COG0174	glutamine synthetase
PB01_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB01_RS07145	COG0765	amino acid transport
PB01_RS07150	COG1126	abc transporter atp-binding protein
PB01_RS07175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PB01_RS07190	COG3763	UPF0154 protein
PB01_RS07195	COG1073	alpha beta
PB01_RS07200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PB01_RS07220	COG0583	DNA-binding transcription factor activity
PB01_RS07225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PB01_RS07230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS07255	COG0667	Aldo Keto reductase
PB01_RS07260	COG0494	nUDIX hydrolase
PB01_RS07270	COG0735	belongs to the Fur family
PB01_RS07275	COG4974	Belongs to the 'phage' integrase family
PB01_RS07280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PB01_RS07285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PB01_RS07290	COG1595	DNA-templated transcription, initiation
PB01_RS07295	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB01_RS07315	COG0697	spore germination
PB01_RS07320	COG0019	diaminopimelate decarboxylase activity
PB01_RS07325	COG0456	acetyltransferase
PB01_RS07330	COG1547	Domain of unknown function (DUF309)
PB01_RS07335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PB01_RS07340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PB01_RS07345	COG1686	Belongs to the peptidase S11 family
PB01_RS07350	COG1187	pseudouridine synthase activity
PB01_RS07355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS07360	COG1333	cytochrome c biogenesis protein
PB01_RS07365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PB01_RS07370	COG0745	RESPONSE REGULATOR receiver
PB01_RS07375	COG5002	protein histidine kinase activity
PB01_RS07380	COG1595	DNA-templated transcription, initiation
PB01_RS07390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PB01_RS07395	COG1141	Ferredoxin
PB01_RS07405	COG0514	ATP-dependent DNA helicase (RecQ)
PB01_RS07410	COG1388	LysM domain
PB01_RS07420	COG1408	metallophosphoesterase
PB01_RS07425	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS07435	COG2339	peptidase activity
PB01_RS07440	COG3773	Cell wall hydrolase
PB01_RS07440	COG3409	Peptidoglycan-binding domain 1 protein
PB01_RS07445	COG2959	enzyme of heme biosynthesis
PB01_RS07460	COG0204	Acyl-transferase
PB01_RS07465	COG0539	negative regulation of cytoplasmic translation
PB01_RS07530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PB01_RS07560	COG0142	geranyltranstransferase activity
PB01_RS07565	COG0105	UTP biosynthetic process
PB01_RS07570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PB01_RS07585	COG4401	Chorismate mutase type I
PB01_RS07595	COG0287	Prephenate dehydrogenase
PB01_RS07600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PB01_RS07605	COG0457	Tetratricopeptide repeat
PB01_RS07620	COG0723	plastoquinol--plastocyanin reductase activity
PB01_RS07635	COG4347	Protein of unknown function (DUF1405)
PB01_RS07640	COG2738	Putative neutral zinc metallopeptidase
PB01_RS07645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS07650	COG1694	Mazg nucleotide pyrophosphohydrolase
PB01_RS07665	COG0438	transferase activity, transferring glycosyl groups
PB01_RS07670	COG0617	tRNA 3'-terminal CCA addition
PB01_RS07675	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PB01_RS07675	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PB01_RS07690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PB01_RS07695	COG1199	ATP-dependent helicase activity
PB01_RS07695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PB01_RS07710	COG0017	Asparaginyl-tRNA synthetase
PB01_RS07715	COG3935	DnaD domain protein
PB01_RS07720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PB01_RS07730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PB01_RS07730	COG4499	WXG100 protein secretion system (Wss), protein YukC
PB01_RS07745	COG1205	dead DEAH box helicase
PB01_RS07745	COG1111	helicase
PB01_RS07750	COG3359	exonuclease
PB01_RS07755	COG3599	regulation of cell shape
PB01_RS07770	COG0116	Belongs to the methyltransferase superfamily
PB01_RS07775	COG1199	ATP-dependent helicase activity
PB01_RS07780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PB01_RS07805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PB01_RS07820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PB01_RS07835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PB01_RS07855	COG0753	catalase activity
PB01_RS07860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PB01_RS07865	COG0431	NADPH-dependent FMN reductase
PB01_RS07870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PB01_RS07875	COG0107	imidazoleglycerol-phosphate synthase activity
PB01_RS07905	COG5577	PFAM Coat F domain
PB01_RS07930	COG1024	Enoyl-CoA hydratase
PB01_RS07935	COG2011	ABC-type metal ion transport system permease component
PB01_RS07945	COG1464	Belongs to the NlpA lipoprotein family
PB01_RS07955	COG0436	Aminotransferase
PB01_RS08065	COG1674	ftsk spoiiie
PB01_RS08120	COG0741	lytic transglycosylase activity
PB01_RS08120	COG1196	nuclear chromosome segregation
PB01_RS08120	COG0739	heme binding
PB01_RS08230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PB01_RS08240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS08245	COG2270	Major facilitator Superfamily
PB01_RS08260	COG2814	Major facilitator Superfamily
PB01_RS08285	COG0411	ABC transporter
PB01_RS08295	COG3706	GGDEF domain
PB01_RS08300	COG2822	iron ion transport
PB01_RS08305	COG2837	iron assimilation
PB01_RS08310	COG0672	)-iron permease
PB01_RS08320	COG1764	response to oxidative stress
PB01_RS08330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PB01_RS08345	COG1278	Cold shock
PB01_RS08355	COG0328	RNA-DNA hybrid ribonuclease activity
PB01_RS08370	COG1846	Transcriptional regulator
PB01_RS08375	COG0346	lactoylglutathione lyase activity
PB01_RS08380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB01_RS08385	COG0431	NADPH-dependent FMN reductase
PB01_RS08410	COG0583	DNA-binding transcription factor activity
PB01_RS08430	COG1418	mRNA catabolic process
PB01_RS08435	COG0488	(ABC) transporter
PB01_RS08440	COG1413	lyase activity
PB01_RS08445	COG0583	DNA-binding transcription factor activity
PB01_RS08450	COG1647	Serine aminopeptidase, S33
PB01_RS08480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS08550	COG0662	Cupin 2, conserved barrel domain protein
PB01_RS08600	COG1657	PFAM Prenyltransferase squalene oxidase
PB01_RS08675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PB01_RS08680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PB01_RS08685	COG1307	EDD domain protein, DegV family
PB01_RS08690	COG2755	lipolytic protein G-D-S-L family
PB01_RS08710	COG0840	transmembrane signaling receptor activity
PB01_RS08715	COG4479	Belongs to the UPF0346 family
PB01_RS08720	COG0813	purine-nucleoside phosphorylase activity
PB01_RS08725	COG3409	Peptidoglycan-binding domain 1 protein
PB01_RS08725	COG0793	Belongs to the peptidase S41A family
PB01_RS08730	COG0523	cobalamin synthesis protein
PB01_RS08740	COG2340	Cysteine-rich secretory protein family
PB01_RS08745	COG0697	spore germination
PB01_RS08760	COG0534	Mate efflux family protein
PB01_RS08780	COG5002	protein histidine kinase activity
PB01_RS08785	COG0567	Dehydrogenase, E1 component
PB01_RS08790	COG0508	dehydrogenase complex catalyzes the overall conversion of
PB01_RS08800	COG0714	Associated with various cellular activities
PB01_RS08805	COG4548	von Willebrand factor, type A
PB01_RS08810	COG3853	Toxic anion resistance protein (TelA)
PB01_RS08815	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PB01_RS08830	COG1278	Cold shock
PB01_RS08835	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS08845	COG0488	(ABC) transporter
PB01_RS08850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PB01_RS08860	COG0628	permease
PB01_RS08875	COG0488	(ABC) transporter
PB01_RS08885	COG0667	Aldo Keto reductase
PB01_RS08935	COG0346	lactoylglutathione lyase activity
PB01_RS08945	COG0546	phosphoglycolate phosphatase activity
PB01_RS08965	COG1191	sigma factor activity
PB01_RS09050	COG4974	Belongs to the 'phage' integrase family
PB01_RS09090	COG0456	acetyltransferase
PB01_RS09090	COG0454	-acetyltransferase
PB01_RS09105	COG5566	PFAM Mor transcription activator
PB01_RS09125	COG1595	DNA-templated transcription, initiation
PB01_RS09155	COG1136	(ABC) transporter
PB01_RS09185	COG1695	Transcriptional regulator
PB01_RS09205	COG1595	DNA-templated transcription, initiation
PB01_RS09255	COG3344	reverse transcriptase
PB01_RS09310	COG0436	Aminotransferase
PB01_RS09315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PB01_RS09320	COG0174	glutamine synthetase
PB01_RS09325	COG0367	asparagine synthase
PB01_RS09355	COG2814	Major facilitator Superfamily
PB01_RS09370	COG3344	reverse transcriptase
PB01_RS09400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PB01_RS09405	COG1940	carbohydrate kinase activity
PB01_RS09420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PB01_RS09425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PB01_RS09435	COG0135	phosphoribosylanthranilate isomerase activity
PB01_RS09440	COG0133	tryptophan synthase activity
PB01_RS09450	COG2814	Major facilitator Superfamily
PB01_RS09455	COG1280	lysine exporter protein (LysE YggA)
PB01_RS09485	COG0204	Acyl-transferase
PB01_RS09500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS09510	COG3829	transcription factor binding
PB01_RS09515	COG1114	Component of the transport system for branched-chain amino acids
PB01_RS09520	COG0697	spore germination
PB01_RS09540	COG4974	Belongs to the 'phage' integrase family
PB01_RS09545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS09555	COG1247	-acetyltransferase
PB01_RS09580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PB01_RS09585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PB01_RS09615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PB01_RS09620	COG0187	DNA topoisomerase II activity
PB01_RS09625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PB01_RS09630	COG4841	protein insertion into membrane
PB01_RS09640	COG0824	Thioesterase
PB01_RS09645	COG0318	PFAM AMP-dependent synthetase and ligase
PB01_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS09680	COG0411	ABC transporter
PB01_RS09695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS09705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PB01_RS09715	COG0535	radical SAM domain protein
PB01_RS09720	COG1335	isochorismatase
PB01_RS09735	COG1999	signal sequence binding
PB01_RS09760	COG4846	Membrane protein involved in cytochrome C biogenesis
PB01_RS09765	COG2201	protein-glutamate methylesterase activity
PB01_RS09770	COG0785	Cytochrome C biogenesis protein
PB01_RS09775	COG1132	(ABC) transporter
PB01_RS09780	COG1132	(ABC) transporter
PB01_RS09805	COG1476	TRANSCRIPTIONal
PB01_RS09815	COG2205	protein histidine kinase activity
PB01_RS09825	COG2140	Oxalate decarboxylase
PB01_RS09835	COG2226	methyltransferase
PB01_RS09845	COG1595	DNA-templated transcription, initiation
PB01_RS09900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PB01_RS09920	COG0307	riboflavin synthase, alpha
PB01_RS09950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PB01_RS09960	COG0640	Transcriptional regulator
PB01_RS09965	COG3832	glyoxalase III activity
PB01_RS09970	COG0640	Transcriptional regulator
PB01_RS09975	COG1940	carbohydrate kinase activity
PB01_RS09980	COG2017	converts alpha-aldose to the beta-anomer
PB01_RS09985	COG1914	H( )-stimulated, divalent metal cation uptake system
PB01_RS09990	COG2720	vancomycin resistance protein
PB01_RS09995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PB01_RS10005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB01_RS10010	COG1609	Transcriptional regulator
PB01_RS10035	COG1554	hydrolase, family 65, central catalytic
PB01_RS10060	COG3842	ATPase activity
PB01_RS10065	COG2508	Transcriptional regulator
PB01_RS10070	COG0165	Argininosuccinate lyase
PB01_RS10075	COG0137	argininosuccinate synthase activity
PB01_RS10080	COG1902	pentaerythritol trinitrate reductase activity
PB01_RS10095	COG1396	sequence-specific DNA binding
PB01_RS10120	COG1042	CoA-binding domain protein
PB01_RS10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS10120	COG0045	succinate-CoA ligase (ADP-forming) activity
PB01_RS10125	COG0590	tRNA wobble adenosine to inosine editing
PB01_RS10240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PB01_RS10245	COG2233	PERMEase
PB01_RS10255	COG3257	ureidoglycine aminohydrolase activity
PB01_RS10260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB01_RS10265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PB01_RS10280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PB01_RS10285	COG2508	Transcriptional regulator
PB01_RS10295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PB01_RS10325	COG3973	AAA domain
PB01_RS10335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS10355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PB01_RS10360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PB01_RS10370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB01_RS10375	COG1116	anion transmembrane transporter activity
PB01_RS10395	COG2755	lipolytic protein G-D-S-L family
PB01_RS10420	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS10425	COG1252	NADH dehydrogenase
PB01_RS10445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PB01_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS10490	COG0477	Major facilitator Superfamily
PB01_RS10495	COG2197	response regulator
PB01_RS10530	COG0501	Belongs to the peptidase M48B family
PB01_RS10575	COG1657	PFAM Prenyltransferase squalene oxidase
PB01_RS10650	COG0590	tRNA wobble adenosine to inosine editing
PB01_RS10665	COG2368	4-hydroxyphenylacetate
PB01_RS10690	COG2814	Major facilitator Superfamily
PB01_RS10695	COG1733	regulation of RNA biosynthetic process
PB01_RS10700	COG0656	L-ascorbic acid biosynthetic process
PB01_RS10725	COG1309	transcriptional regulator
PB01_RS10760	COG1309	transcriptional regulator
PB01_RS10765	COG0702	epimerase
PB01_RS10795	COG3344	reverse transcriptase
PB01_RS10820	COG1595	DNA-templated transcription, initiation
PB01_RS10890	COG4974	Belongs to the 'phage' integrase family
PB01_RS10930	COG3344	reverse transcriptase
PB01_RS10955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PB01_RS10955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PB01_RS10960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PB01_RS10960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PB01_RS10980	COG0346	lactoylglutathione lyase activity
PB01_RS10985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PB01_RS11010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB01_RS11030	COG0300	oxidoreductase activity
PB01_RS11035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB01_RS11040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PB01_RS11045	COG1234	tRNA 3'-trailer cleavage
PB01_RS11055	COG0835	chemotaxis
PB01_RS11060	COG2195	Cleaves the N-terminal amino acid of tripeptides
PB01_RS11065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PB01_RS11070	COG0346	lactoylglutathione lyase activity
PB01_RS11090	COG1703	isobutyryl-CoA mutase activity
PB01_RS11095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PB01_RS11095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PB01_RS11130	COG0456	acetyltransferase
PB01_RS11135	COG2211	Major facilitator Superfamily
PB01_RS11155	COG2205	protein histidine kinase activity
PB01_RS11185	COG1247	-acetyltransferase
PB01_RS11190	COG0572	uridine kinase
PB01_RS11250	COG1162	GTPase activity
PB01_RS11255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PB01_RS11290	COG0772	Belongs to the SEDS family
PB01_RS11300	COG1595	DNA-templated transcription, initiation
PB01_RS11330	COG1846	Transcriptional regulator
PB01_RS11335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB01_RS11345	COG2011	ABC-type metal ion transport system permease component
PB01_RS11350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PB01_RS11355	COG0508	dehydrogenase complex catalyzes the overall conversion of
PB01_RS11360	COG0022	dehydrogenase e1 component
PB01_RS11365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PB01_RS11370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PB01_RS11380	COG3290	protein histidine kinase activity
PB01_RS11380	COG3829	transcription factor binding
PB01_RS11390	COG0584	glycerophosphoryl diester phosphodiesterase
PB01_RS11405	COG0750	zinc metalloprotease
PB01_RS11410	COG0497	DNA recombination
PB01_RS11415	COG1438	arginine binding
PB01_RS11420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PB01_RS11425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PB01_RS11430	COG0142	geranyltranstransferase activity
PB01_RS11455	COG1302	Protein conserved in bacteria
PB01_RS11460	COG0439	Biotin carboxylase
PB01_RS11465	COG0511	ligase activity, forming carbon-carbon bonds
PB01_RS11500	COG0006	proline dipeptidase activity
PB01_RS11510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PB01_RS11520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB01_RS11535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PB01_RS11540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PB01_RS11560	COG4970	Tfp pilus assembly protein FimT
PB01_RS11565	COG4537	Required for transformation and DNA binding
PB01_RS11570	COG1459	type II secretion system
PB01_RS11575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PB01_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB01_RS11600	COG1368	sulfuric ester hydrolase activity
PB01_RS11610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PB01_RS11615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PB01_RS11635	COG0704	Plays a role in the regulation of phosphate uptake
PB01_RS11640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PB01_RS11645	COG0581	inorganic phosphate transmembrane transporter activity
PB01_RS11650	COG0573	inorganic phosphate transmembrane transporter activity
PB01_RS11655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PB01_RS11660	COG0768	penicillin binding
PB01_RS11670	COG2839	Protein conserved in bacteria
PB01_RS11675	COG1283	sodium-dependent phosphate transmembrane transporter activity
PB01_RS11690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PB01_RS11695	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
PB01_RS11705	COG0735	belongs to the Fur family
PB01_RS11710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB01_RS11715	COG1121	(ABC) transporter
PB01_RS11730	COG0513	Belongs to the DEAD box helicase family
PB01_RS11745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PB01_RS11750	COG2384	SAM-dependent methyltransferase
PB01_RS11760	COG1960	acyl-CoA dehydrogenase activity
PB01_RS11770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PB01_RS11775	COG0358	DNA primase activity
PB01_RS11785	COG0517	IMP dehydrogenase activity
PB01_RS11795	COG1381	Involved in DNA repair and RecF pathway recombination
PB01_RS11810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PB01_RS11820	COG1480	7TM receptor with intracellular HD hydrolase
PB01_RS11830	COG1702	phosphate starvation-inducible protein PhoH
PB01_RS11850	COG4864	UPF0365 protein
PB01_RS11855	COG1030	water channel activity
PB01_RS11860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PB01_RS11870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PB01_RS11875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PB01_RS11880	COG2264	protein methyltransferase activity
PB01_RS11885	COG0484	heat shock protein binding
PB01_RS11890	COG0443	Heat shock 70 kDa protein
PB01_RS11905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PB01_RS11920	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PB01_RS11930	COG1466	dna polymerase III delta subunit
PB01_RS11940	COG0658	competence protein
PB01_RS11940	COG2333	competence protein COMEC
PB01_RS11945	COG2131	deaminase
PB01_RS11950	COG1555	photosystem II stabilization
PB01_RS11950	COG1596	polysaccharide export
PB01_RS11955	COG2226	methyltransferase
PB01_RS11960	COG0799	negative regulation of ribosome biogenesis
PB01_RS11965	COG1713	HD superfamily hydrolase involved in NAD metabolism
PB01_RS11970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PB01_RS11975	COG1534	Rna-binding protein
PB01_RS11985	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PB01_RS11990	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
PB01_RS12000	COG1183	phosphatidylcholine synthase activity
PB01_RS12020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PB01_RS12025	COG0572	uridine kinase
PB01_RS12030	COG0826	peptidase U32
PB01_RS12035	COG0826	peptidase U32
PB01_RS12040	COG4122	O-methyltransferase activity
PB01_RS12045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PB01_RS12050	COG3906	Belongs to the UPF0473 family
PB01_RS12055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PB01_RS12060	COG4472	Bacterial protein of unknown function (DUF965)
PB01_RS12065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PB01_RS12070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PB01_RS12075	COG0457	Tetratricopeptide repeat
PB01_RS12085	COG1104	cysteine desulfurase activity
PB01_RS12090	COG1959	2 iron, 2 sulfur cluster binding
PB01_RS12095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PB01_RS12105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PB01_RS12115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PB01_RS12125	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB01_RS12125	COG3103	Sh3 type 3 domain protein
PB01_RS12125	COG4991	sh3 domain protein
PB01_RS12135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PB01_RS12140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PB01_RS12145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PB01_RS12145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PB01_RS12150	COG5416	Lipopolysaccharide assembly protein A domain
PB01_RS12155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PB01_RS12155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PB01_RS12165	COG2244	polysaccharide biosynthetic process
PB01_RS12170	COG2323	membrane
PB01_RS12175	COG1862	Preprotein translocase
PB01_RS12180	COG0343	queuine tRNA-ribosyltransferase activity
PB01_RS12210	COG0077	Prephenate dehydratase
PB01_RS12235	COG2868	ribosomal protein
PB01_RS12245	COG1994	Peptidase M50
PB01_RS12255	COG2894	cell division
PB01_RS12260	COG0850	regulation of cytokinetic process
PB01_RS12270	COG1792	Involved in formation and maintenance of cell shape
PB01_RS12275	COG1077	Cell shape determining protein MreB Mrl
PB01_RS12280	COG2003	Belongs to the UPF0758 family
PB01_RS12295	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PB01_RS12300	COG3706	GGDEF domain
PB01_RS12325	COG1459	type II secretion system
PB01_RS12335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PB01_RS12365	COG0285	dihydrofolate synthase activity
PB01_RS12370	COG0189	ligase activity
PB01_RS12380	COG0525	valine-tRNA ligase activity
PB01_RS12395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PB01_RS12400	COG0113	porphobilinogen synthase activity
PB01_RS12415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PB01_RS12425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PB01_RS12430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PB01_RS12445	COG0457	Tetratricopeptide repeat
PB01_RS12445	COG1477	protein flavinylation
PB01_RS12470	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PB01_RS12510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PB01_RS12530	COG0622	Phosphoesterase
PB01_RS12535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PB01_RS12550	COG1846	Transcriptional regulator
PB01_RS12555	COG2197	response regulator
PB01_RS12560	COG0824	Thioesterase
PB01_RS12565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PB01_RS12570	COG1053	succinate dehydrogenase
PB01_RS12575	COG2009	succinate dehydrogenase
PB01_RS12580	COG1719	4-vinyl reductase, 4VR
PB01_RS12600	COG3118	belongs to the thioredoxin family
PB01_RS12605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PB01_RS12610	COG2086	electron transfer activity
PB01_RS12615	COG1024	Enoyl-CoA hydratase
PB01_RS12620	COG1309	transcriptional regulator
PB01_RS12625	COG0318	PFAM AMP-dependent synthetase and ligase
PB01_RS12630	COG3766	membrane
PB01_RS12635	COG1193	negative regulation of DNA recombination
PB01_RS12640	COG1796	DNA polymerase
PB01_RS12640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PB01_RS12660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PB01_RS12675	COG2986	histidine ammonia-lyase
PB01_RS12680	COG2195	Cleaves the N-terminal amino acid of tripeptides
PB01_RS12685	COG1228	amidohydrolase
PB01_RS12695	COG1126	abc transporter atp-binding protein
PB01_RS12700	COG0765	amino acid transport
PB01_RS12705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB01_RS12710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PB01_RS12715	COG3829	transcription factor binding
PB01_RS12720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PB01_RS12740	COG0456	acetyltransferase
PB01_RS12740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PB01_RS12760	COG0072	phenylalanine-tRNA ligase activity
PB01_RS12760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB01_RS12770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PB01_RS12785	COG1476	TRANSCRIPTIONal
PB01_RS12790	COG0277	FAD linked oxidase domain protein
PB01_RS12795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PB01_RS12800	COG1363	Peptidase, m42
PB01_RS12830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PB01_RS12835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PB01_RS12840	COG1484	DNA-dependent DNA replication
PB01_RS12845	COG3611	Membrane attachment protein
PB01_RS12860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PB01_RS12865	COG0237	dephospho-CoA kinase activity
PB01_RS12870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PB01_RS12875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB01_RS12875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB01_RS12880	COG0330	HflC and HflK could
PB01_RS12885	COG0330	HflC and HflK could
PB01_RS12895	COG5002	protein histidine kinase activity
PB01_RS12900	COG0745	RESPONSE REGULATOR receiver
PB01_RS12915	COG0538	isocitrate dehydrogenase activity
PB01_RS12920	COG0372	Belongs to the citrate synthase family
PB01_RS12925	COG0628	permease
PB01_RS12930	COG3030	protein affecting phage T7 exclusion by the F plasmid
PB01_RS12940	COG0205	6-phosphofructokinase activity
PB01_RS12945	COG0825	malonyl-CoA metabolic process
PB01_RS12955	COG1725	Transcriptional regulator
PB01_RS12960	COG0587	DNA-directed DNA polymerase activity
PB01_RS12965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PB01_RS12975	COG4109	DRTGG domain
PB01_RS12985	COG0006	proline dipeptidase activity
PB01_RS12990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PB01_RS12995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PB01_RS13005	COG0589	response to stress
PB01_RS13020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PB01_RS13025	COG0827	DNA restriction-modification system
PB01_RS13030	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PB01_RS13035	COG1714	RDD family
PB01_RS13040	COG0616	signal peptide processing
PB01_RS13050	COG2962	Rard protein
PB01_RS13055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PB01_RS13070	COG1104	cysteine desulfurase activity
PB01_RS13075	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PB01_RS13080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PB01_RS13085	COG1956	GAF domain-containing protein
PB01_RS13090	COG0069	glutamate synthase activity
PB01_RS13095	COG0626	cystathionine gamma-synthase activity
PB01_RS13100	COG2199	diguanylate cyclase activity
PB01_RS13100	COG2203	Gaf domain
PB01_RS13115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PB01_RS13125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PB01_RS13130	COG0454	-acetyltransferase
PB01_RS13135	COG0517	IMP dehydrogenase activity
PB01_RS13140	COG0123	including yeast histone deacetylase and acetoin utilization protein
PB01_RS13150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PB01_RS13150	COG1605	Chorismate mutase
PB01_RS13155	COG0849	cell division
PB01_RS13160	COG4980	gas vesicle protein
PB01_RS13165	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PB01_RS13175	COG1674	ftsk spoiiie
PB01_RS13180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB01_RS13185	COG4848	Belongs to the UPF0354 family
PB01_RS13190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS13200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PB01_RS13205	COG1363	Peptidase, m42
PB01_RS13210	COG5584	Small secreted protein
PB01_RS13215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB01_RS13225	COG1597	lipid kinase activity
PB01_RS13245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB01_RS13255	COG1349	DNA-binding transcription factor activity
PB01_RS13260	COG1187	pseudouridine synthase activity
PB01_RS13265	COG2244	polysaccharide biosynthetic process
PB01_RS13270	COG2081	HI0933 family
PB01_RS13290	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
PB01_RS13300	COG0495	leucyl-tRNA aminoacylation
PB01_RS13305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PB01_RS13310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PB01_RS13315	COG2814	Major facilitator Superfamily
PB01_RS13320	COG1242	4 iron, 4 sulfur cluster binding
PB01_RS13325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PB01_RS13330	COG3424	synthase
PB01_RS13335	COG1755	Isoprenylcysteine carboxyl methyltransferase
PB01_RS13340	COG0281	malic enzyme
PB01_RS13345	COG2267	carboxylic ester hydrolase activity
PB01_RS13350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PB01_RS13370	COG1506	peptidase
PB01_RS13400	COG0783	Belongs to the Dps family
PB01_RS13405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PB01_RS13415	COG0318	PFAM AMP-dependent synthetase and ligase
PB01_RS13420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PB01_RS13425	COG0596	Alpha beta hydrolase
PB01_RS13435	COG1169	isochorismate synthase
PB01_RS13440	COG1575	Belongs to the MenA family. Type 1 subfamily
PB01_RS13560	COG1285	pathogenesis
PB01_RS13570	COG1979	alcohol dehydrogenase
PB01_RS13580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PB01_RS13585	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS13590	COG3829	transcription factor binding
PB01_RS13595	COG1098	S1 RNA binding domain
PB01_RS13605	COG1595	DNA-templated transcription, initiation
PB01_RS13610	COG0733	neurotransmitter:sodium symporter activity
PB01_RS13625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PB01_RS13635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PB01_RS13640	COG2814	Major facilitator Superfamily
PB01_RS13645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PB01_RS13650	COG2814	Major facilitator Superfamily
PB01_RS13655	COG1309	transcriptional regulator
PB01_RS13665	COG2111	Na H antiporter
PB01_RS13665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PB01_RS13670	COG2111	Na H antiporter
PB01_RS13675	COG1006	Multisubunit Na H antiporter MnhC subunit
PB01_RS13680	COG0651	ATP synthesis coupled electron transport
PB01_RS13685	COG1863	multisubunit Na H antiporter MnhE subunit
PB01_RS13690	COG2212	antiporter activity
PB01_RS13695	COG1320	monovalent cation:proton antiporter activity
PB01_RS13705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PB01_RS13710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
PB01_RS13725	COG1252	NADH dehydrogenase
PB01_RS13730	COG0316	Belongs to the HesB IscA family
PB01_RS13740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PB01_RS13745	COG4837	Protein of unknown function (DUF1462)
PB01_RS13750	COG1252	NADH dehydrogenase
PB01_RS13755	COG4844	belongs to the
PB01_RS13760	COG0647	UMP catabolic process
PB01_RS13765	COG2445	Protein of unknown function DUF86
PB01_RS13775	COG4470	Protein conserved in bacteria
PB01_RS13780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PB01_RS13790	COG0737	Belongs to the 5'-nucleotidase family
PB01_RS13795	COG0730	response to heat
PB01_RS13800	COG1801	Protein of unknown function DUF72
PB01_RS13805	COG0719	Fe-S assembly protein
PB01_RS13810	COG0822	iron-sulfur transferase activity
PB01_RS13815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PB01_RS13820	COG0719	Fe-S assembly protein
PB01_RS13825	COG0396	ATPase activity
PB01_RS13835	COG1464	Belongs to the NlpA lipoprotein family
PB01_RS13840	COG2011	ABC-type metal ion transport system permease component
PB01_RS13850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS13855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PB01_RS13865	COG0509	glycine decarboxylation via glycine cleavage system
PB01_RS13870	COG1393	Belongs to the ArsC family
PB01_RS13875	COG1960	acyl-CoA dehydrogenase activity
PB01_RS13880	COG0183	Belongs to the thiolase family
PB01_RS13885	COG1250	3-hydroxyacyl-CoA dehydrogenase
PB01_RS13885	COG1024	Enoyl-CoA hydratase
PB01_RS13890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS13910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB01_RS13915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PB01_RS13920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PB01_RS13970	COG1216	Glycosyl transferase, family 2
PB01_RS13970	COG1442	glycosyl transferase family 8
PB01_RS13975	COG1215	transferase activity, transferring glycosyl groups
PB01_RS14000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB01_RS14020	COG0489	protein tyrosine kinase activity
PB01_RS14025	COG3944	biosynthesis protein
PB01_RS14030	COG4464	protein tyrosine phosphatase activity
PB01_RS14035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PB01_RS14045	COG1595	DNA-templated transcription, initiation
PB01_RS14060	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS14070	COG2066	Belongs to the glutaminase family
PB01_RS14075	COG1285	pathogenesis
PB01_RS14085	COG1902	pentaerythritol trinitrate reductase activity
PB01_RS14105	COG2329	Antibiotic biosynthesis monooxygenase
PB01_RS14110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB01_RS14135	COG1288	antiporter activity
PB01_RS14140	COG1473	amidohydrolase
PB01_RS14175	COG3973	AAA domain
PB01_RS14200	COG5002	protein histidine kinase activity
PB01_RS14215	COG0477	Major facilitator Superfamily
PB01_RS14220	COG1368	sulfuric ester hydrolase activity
PB01_RS14270	COG0210	DNA helicase
PB01_RS14300	COG3344	reverse transcriptase
PB01_RS14370	COG3173	Aminoglycoside phosphotransferase
PB01_RS14395	COG0557	exoribonuclease II activity
PB01_RS14400	COG1647	Serine aminopeptidase, S33
PB01_RS14405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PB01_RS14450	COG0454	-acetyltransferase
PB01_RS14490	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PB01_RS14500	COG0126	phosphoglycerate kinase activity
PB01_RS14530	COG0456	acetyltransferase
PB01_RS14540	COG1704	LemA family
PB01_RS14545	COG0753	catalase activity
PB01_RS14555	COG3850	Histidine kinase
PB01_RS14555	COG5002	protein histidine kinase activity
PB01_RS14565	COG1408	metallophosphoesterase
PB01_RS14580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB01_RS14590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PB01_RS14600	COG1051	belongs to the nudix hydrolase family
PB01_RS14605	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS14610	COG0457	Tetratricopeptide repeat
PB01_RS14615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PB01_RS14615	COG0140	phosphoribosyl-ATP diphosphatase activity
PB01_RS14620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PB01_RS14625	COG0131	Imidazoleglycerol-phosphate dehydratase
PB01_RS14630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PB01_RS14645	COG0110	maltose O-acetyltransferase activity
PB01_RS14650	COG0546	phosphoglycolate phosphatase activity
PB01_RS14655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PB01_RS14665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PB01_RS14670	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB01_RS14675	COG3595	metallopeptidase activity
PB01_RS14680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PB01_RS14685	COG0556	nucleotide-excision repair
PB01_RS14705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PB01_RS14710	COG1024	Enoyl-CoA hydratase
PB01_RS14715	COG0277	FAD linked oxidase domain protein
PB01_RS14720	COG2271	Major facilitator Superfamily
PB01_RS14735	COG0588	phosphoglycerate mutase activity
PB01_RS14800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB01_RS14825	COG2226	methyltransferase
PB01_RS14850	COG2155	Conserved Protein
PB01_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS14890	COG1136	(ABC) transporter
PB01_RS14895	COG0577	efflux transmembrane transporter activity
PB01_RS14905	COG0697	spore germination
PB01_RS14920	COG1595	DNA-templated transcription, initiation
PB01_RS14965	COG2226	methyltransferase
PB01_RS14970	COG5504	Zn-dependent protease
PB01_RS15000	COG0626	cystathionine gamma-synthase activity
PB01_RS15005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PB01_RS15015	COG2226	methyltransferase
PB01_RS15035	COG1619	proteins homologs of microcin C7 resistance protein MccF
PB01_RS15040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PB01_RS15050	COG0390	transport system, permease component
PB01_RS15055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PB01_RS15065	COG1113	amino acid transport
PB01_RS15070	COG0823	Involved in the tonB-independent uptake of proteins
PB01_RS15070	COG4946	Tricorn protease homolog
PB01_RS15070	COG1506	peptidase
PB01_RS15075	COG0318	PFAM AMP-dependent synthetase and ligase
PB01_RS15080	COG0577	efflux transmembrane transporter activity
PB01_RS15085	COG1136	(ABC) transporter
PB01_RS15090	COG2205	protein histidine kinase activity
PB01_RS15095	COG0745	RESPONSE REGULATOR receiver
PB01_RS15100	COG0095	Lipoate-protein ligase
PB01_RS15110	COG1349	DNA-binding transcription factor activity
PB01_RS15115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB01_RS15185	COG3344	reverse transcriptase
PB01_RS15195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS15200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PB01_RS15245	COG1511	domain protein
PB01_RS15250	COG1309	transcriptional regulator
PB01_RS15260	COG5002	protein histidine kinase activity
PB01_RS15265	COG0745	RESPONSE REGULATOR receiver
PB01_RS15280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PB01_RS15285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PB01_RS15290	COG2329	Antibiotic biosynthesis monooxygenase
PB01_RS15295	COG1473	amidohydrolase
PB01_RS15300	COG4473	ABC transporter
PB01_RS15305	COG1131	(ABC) transporter
PB01_RS15310	COG0537	adenosine 5'-monophosphoramidase activity
PB01_RS15345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PB01_RS15355	COG3481	metal-dependent phosphohydrolase, HD sub domain
PB01_RS15360	COG4717	serine-type aminopeptidase activity
PB01_RS15365	COG0420	3'-5' exonuclease activity
PB01_RS15400	COG1024	Enoyl-CoA hydratase
PB01_RS15440	COG1476	TRANSCRIPTIONal
PB01_RS15445	COG1132	(ABC) transporter
PB01_RS15450	COG1132	(ABC) transporter
PB01_RS15455	COG1253	flavin adenine dinucleotide binding
PB01_RS15460	COG2197	response regulator
PB01_RS15465	COG4585	Histidine kinase
PB01_RS15465	COG2203	Gaf domain
PB01_RS15470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PB01_RS15475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PB01_RS15475	COG3153	acetyltransferase
PB01_RS15480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PB01_RS15485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB01_RS15490	COG0564	pseudouridine synthase activity
PB01_RS15535	COG0656	L-ascorbic acid biosynthetic process
PB01_RS15545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PB01_RS15550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PB01_RS15555	COG3382	B3 4 domain protein
PB01_RS15565	COG1595	DNA-templated transcription, initiation
PB01_RS15570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PB01_RS15690	COG0735	belongs to the Fur family
PB01_RS15700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PB01_RS15710	COG4129	membrane
PB01_RS15725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS15730	COG0601	transmembrane transport
PB01_RS15735	COG0747	negative chemotaxis
PB01_RS15740	COG4608	Belongs to the ABC transporter superfamily
PB01_RS15745	COG0444	Belongs to the ABC transporter superfamily
PB01_RS15750	COG1132	(ABC) transporter
PB01_RS15755	COG3557	Belongs to the UPF0374 family
PB01_RS15765	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS15770	COG1194	a g-specific adenine glycosylase
PB01_RS15775	COG1988	membrane-bound metal-dependent
PB01_RS15795	COG1090	epimerase
PB01_RS15805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PB01_RS15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB01_RS15860	COG0477	Major facilitator Superfamily
PB01_RS15875	COG2217	Heavy metal translocating P-type atpase
PB01_RS15880	COG1011	Hydrolase
PB01_RS15890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PB01_RS15900	COG3344	reverse transcriptase
PB01_RS15905	COG1295	ribonuclease BN
PB01_RS15915	COG1115	amino acid carrier protein
PB01_RS15920	COG4840	Belongs to the UPF0435 family
PB01_RS15935	COG1360	Flagellar Motor Protein
PB01_RS15940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PB01_RS15945	COG2309	aminopeptidase activity
PB01_RS15955	COG1077	Cell shape determining protein MreB Mrl
PB01_RS15960	COG0288	reversible hydration of carbon dioxide
PB01_RS15980	COG0024	Methionine aminopeptidase
PB01_RS15985	COG3859	Proton-coupled thiamine transporter YuaJ
PB01_RS15990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB01_RS16005	COG2309	aminopeptidase activity
PB01_RS16010	COG0513	Belongs to the DEAD box helicase family
PB01_RS16035	COG1011	Hydrolase
PB01_RS16040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PB01_RS16045	COG0527	aspartate kinase activity
PB01_RS16050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PB01_RS16060	COG2233	PERMEase
PB01_RS16080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PB01_RS16085	COG1619	proteins homologs of microcin C7 resistance protein MccF
PB01_RS16090	COG0745	RESPONSE REGULATOR receiver
PB01_RS16110	COG3583	domain protein
PB01_RS16110	COG3584	3D domain protein
PB01_RS16115	COG0840	transmembrane signaling receptor activity
PB01_RS16130	COG5566	PFAM Mor transcription activator
PB01_RS16155	COG1174	glycine betaine transport
PB01_RS16160	COG0517	IMP dehydrogenase activity
PB01_RS16160	COG1125	glycine betaine transport
PB01_RS16165	COG0346	lactoylglutathione lyase activity
PB01_RS16195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PB01_RS16205	COG5522	Integral membrane protein (intg_mem_TP0381)
PB01_RS16215	COG1473	amidohydrolase
PB01_RS16240	COG4807	Protein conserved in bacteria
PB01_RS16245	COG1473	amidohydrolase
PB01_RS16250	COG2271	Major facilitator Superfamily
PB01_RS16260	COG0531	amino acid
PB01_RS16265	COG1335	isochorismatase
PB01_RS16270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PB01_RS16285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PB01_RS16290	COG2357	RelA SpoT domain protein
PB01_RS16295	COG1011	Hydrolase
PB01_RS16300	COG1294	oxidase, subunit
PB01_RS16305	COG1271	oxidase subunit
PB01_RS16310	COG1597	lipid kinase activity
PB01_RS16320	COG0840	transmembrane signaling receptor activity
PB01_RS16340	COG4851	CamS sex pheromone cAM373 precursor
PB01_RS16350	COG0210	DNA helicase
PB01_RS16360	COG4496	protein, YerC YecD
PB01_RS16365	COG1470	cell adhesion involved in biofilm formation
PB01_RS16370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PB01_RS16375	COG0151	Belongs to the GarS family
PB01_RS16385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PB01_RS16395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PB01_RS16410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PB01_RS16420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PB01_RS16425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PB01_RS16430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PB01_RS16440	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
PB01_RS16460	COG2252	PERMEase
PB01_RS16465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PB01_RS16465	COG0519	Catalyzes the synthesis of GMP from XMP
PB01_RS16470	COG1305	Transglutaminase-like
PB01_RS16475	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
PB01_RS16480	COG0714	Associated with various cellular activities
PB01_RS16490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PB01_RS16505	COG0708	Exodeoxyribonuclease III
PB01_RS16510	COG0753	catalase activity
PB01_RS16520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB01_RS16540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PB01_RS16570	COG1278	Cold shock
PB01_RS16595	COG0456	acetyltransferase
PB01_RS16620	COG0590	tRNA wobble adenosine to inosine editing
PB01_RS16630	COG0549	Belongs to the carbamate kinase family
PB01_RS16640	COG1304	FMN binding
PB01_RS16645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PB01_RS16655	COG2508	Transcriptional regulator
PB01_RS16660	COG3739	integral membrane protein
PB01_RS16670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PB01_RS16690	COG3844	kynureninase activity
PB01_RS16710	COG0457	Tetratricopeptide repeat
PB01_RS16710	COG0463	Glycosyl transferase, family 2
PB01_RS16725	COG0463	Glycosyl transferase, family 2
PB01_RS16725	COG0457	Tetratricopeptide repeat
PB01_RS16745	COG1263	PTS System
PB01_RS16745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB01_RS16750	COG1263	PTS System
PB01_RS16750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB01_RS16750	COG2190	(PTS) system
PB01_RS16770	COG4821	SIS domain
PB01_RS16775	COG2188	Transcriptional regulator
PB01_RS16790	COG1193	negative regulation of DNA recombination
PB01_RS16815	COG4974	Belongs to the 'phage' integrase family
PB01_RS16820	COG4974	Belongs to the 'phage' integrase family
PB01_RS16825	COG4974	Belongs to the 'phage' integrase family
PB01_RS16855	COG3344	reverse transcriptase
PB01_RS16905	COG0592	DNA-directed DNA polymerase activity
PB01_RS16910	COG0592	DNA-directed DNA polymerase activity
PB01_RS16970	COG2814	Major facilitator Superfamily
PB01_RS16975	COG0477	Major facilitator Superfamily
PB01_RS16985	COG2801	Transposase and inactivated derivatives
PB01_RS17010	COG0592	DNA-directed DNA polymerase activity
PB01_RS17070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PB01_RS17075	COG0183	Belongs to the thiolase family
PB01_RS17080	COG2207	Transcriptional regulator
PB01_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS17110	COG2135	peptidase activity
PB01_RS17125	COG1733	regulation of RNA biosynthetic process
PB01_RS17130	COG0778	Nitroreductase
PB01_RS17135	COG4213	ABC transporter substrate-binding protein
PB01_RS17140	COG4753	response regulator
PB01_RS17140	COG2207	Transcriptional regulator
PB01_RS17145	COG2972	Histidine kinase
PB01_RS17155	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB01_RS17190	COG5290	Psort location Cytoplasmic, score
PB01_RS17200	COG3344	reverse transcriptase
PB01_RS17210	COG4122	O-methyltransferase activity
PB01_RS17215	COG0583	DNA-binding transcription factor activity
PB01_RS17240	COG4974	Belongs to the 'phage' integrase family
PB01_RS17255	COG1266	CAAX protease self-immunity
PB01_RS17265	COG0488	(ABC) transporter
PB01_RS17270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PB01_RS17275	COG0456	acetyltransferase
PB01_RS17280	COG1214	PFAM Peptidase M22, glycoprotease
PB01_RS17285	COG0802	atpase or kinase
PB01_RS17295	COG0829	nickel cation binding
PB01_RS17300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PB01_RS17305	COG0830	nickel cation binding
PB01_RS17310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PB01_RS17315	COG0804	urea catabolic process
PB01_RS17320	COG0832	Belongs to the urease beta subunit family
PB01_RS17325	COG0831	urea catabolic process
PB01_RS17330	COG4413	Urea transporter
PB01_RS17340	COG0788	formyltetrahydrofolate deformylase activity
PB01_RS17345	COG1388	LysM domain
PB01_RS17345	COG3584	3D domain protein
PB01_RS17350	COG0803	Belongs to the bacterial solute-binding protein 9 family
PB01_RS17355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB01_RS17360	COG1121	(ABC) transporter
PB01_RS17370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PB01_RS17375	COG1335	isochorismatase
PB01_RS17395	COG1525	nuclease
PB01_RS17410	COG1272	protein, Hemolysin III
PB01_RS17415	COG1278	Cold shock
PB01_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS17435	COG0653	protein targeting
PB01_RS17440	COG0395	ABC-type sugar transport system, permease component
PB01_RS17450	COG2182	Extracellular solute-binding protein
PB01_RS17460	COG1609	Transcriptional regulator
PB01_RS17490	COG0653	protein targeting
PB01_RS17495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PB01_RS17505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PB01_RS17530	COG1131	(ABC) transporter
PB01_RS17635	COG2183	response to ionizing radiation
PB01_RS17645	COG1191	sigma factor activity
PB01_RS17650	COG2172	sigma factor antagonist activity
PB01_RS17655	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS17660	COG2208	phosphoserine phosphatase activity
PB01_RS17665	COG2172	sigma factor antagonist activity
PB01_RS17670	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS17675	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS17680	COG2337	Toxic component of a toxin-antitoxin (TA) module
PB01_RS17695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PB01_RS17700	COG0736	holo-[acyl-carrier-protein] synthase activity
PB01_RS17705	COG0705	Rhomboid family
PB01_RS17710	COG3428	Bacterial PH domain
PB01_RS17715	COG3402	PFAM membrane-flanked domain
PB01_RS17720	COG0513	Belongs to the DEAD box helicase family
PB01_RS17730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PB01_RS17735	COG1181	Belongs to the D-alanine--D-alanine ligase family
PB01_RS17745	COG0772	Belongs to the SEDS family
PB01_RS17750	COG0517	IMP dehydrogenase activity
PB01_RS17780	COG1823	symporter activity
PB01_RS17785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PB01_RS17790	COG1876	peptidase activity
PB01_RS17835	COG0346	lactoylglutathione lyase activity
PB01_RS17845	COG2996	Protein conserved in bacteria
PB01_RS17855	COG0840	transmembrane signaling receptor activity
PB01_RS17890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PB01_RS17895	COG1733	regulation of RNA biosynthetic process
PB01_RS17900	COG2353	YceI-like domain
PB01_RS17910	COG1473	amidohydrolase
PB01_RS17920	COG1132	(ABC) transporter
PB01_RS17925	COG1132	(ABC) transporter
PB01_RS17930	COG1695	Transcriptional regulator
PB01_RS17935	COG0723	plastoquinol--plastocyanin reductase activity
PB01_RS17935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PB01_RS17945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PB01_RS17950	COG1227	inorganic diphosphatase activity
PB01_RS17955	COG1959	2 iron, 2 sulfur cluster binding
PB01_RS17970	COG2094	Belongs to the DNA glycosylase MPG family
PB01_RS17980	COG0477	Major facilitator Superfamily
PB01_RS17985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PB01_RS17995	COG1573	uracil-dna glycosylase
PB01_RS18005	COG4607	ABC-type enterochelin transport system periplasmic component
PB01_RS18010	COG4604	ABC transporter, ATP-binding protein
PB01_RS18015	COG4605	iron ion homeostasis
PB01_RS18020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS18030	COG3104	oligopeptide transport
PB01_RS18035	COG1132	(ABC) transporter
PB01_RS18040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PB01_RS18050	COG1757	Na H antiporter
PB01_RS18065	COG0577	efflux transmembrane transporter activity
PB01_RS18070	COG1136	(ABC) transporter
PB01_RS18075	COG1595	DNA-templated transcription, initiation
PB01_RS18090	COG0114	fumarate hydratase activity
PB01_RS18095	COG2199	diguanylate cyclase activity
PB01_RS18095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PB01_RS18100	COG2268	Band 7 protein
PB01_RS18105	COG1585	Membrane protein implicated in regulation of membrane protease activity
PB01_RS18110	COG1392	Phosphate transport regulator
PB01_RS18115	COG0306	phosphate transporter
PB01_RS18125	COG2409	Drug exporters of the RND superfamily
PB01_RS18130	COG0400	carboxylic ester hydrolase activity
PB01_RS18135	COG2814	Major facilitator Superfamily
PB01_RS18160	COG2318	DinB family
PB01_RS18165	COG0322	excinuclease ABC activity
PB01_RS18170	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS18175	COG3011	Protein conserved in bacteria
PB01_RS18180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PB01_RS18195	COG1802	Transcriptional regulator
PB01_RS18200	COG1114	Component of the transport system for branched-chain amino acids
PB01_RS18205	COG2814	Major facilitator Superfamily
PB01_RS18210	COG2223	nitrite transmembrane transporter activity
PB01_RS18215	COG2323	membrane
PB01_RS18220	COG1472	Belongs to the glycosyl hydrolase 3 family
PB01_RS18230	COG0406	alpha-ribazole phosphatase activity
PB01_RS18235	COG0789	Transcriptional regulator
PB01_RS18245	COG3695	enzyme binding
PB01_RS18250	COG1695	Transcriptional regulator
PB01_RS18270	COG0592	DNA-directed DNA polymerase activity
PB01_RS18280	COG0710	3-dehydroquinate dehydratase activity
PB01_RS18285	COG0456	acetyltransferase
PB01_RS18290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PB01_RS18295	COG2169	Transcriptional regulator
PB01_RS18300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PB01_RS18310	COG4152	abc transporter atp-binding protein
PB01_RS18315	COG1668	transmembrane transport
PB01_RS18320	COG2358	TRAP transporter, solute receptor (TAXI family
PB01_RS18330	COG0488	(ABC) transporter
PB01_RS18350	COG2816	NAD+ diphosphatase activity
PB01_RS18360	COG0217	transcriptional regulatory protein
PB01_RS18390	COG0494	nUDIX hydrolase
PB01_RS18395	COG3708	Transcriptional regulator
PB01_RS18395	COG2207	Transcriptional regulator
PB01_RS18425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PB01_RS18430	COG0446	pyridine nucleotide-disulphide oxidoreductase
PB01_RS18440	COG0753	catalase activity
PB01_RS18455	COG0745	RESPONSE REGULATOR receiver
PB01_RS18460	COG5002	protein histidine kinase activity
PB01_RS18480	COG1609	Transcriptional regulator
PB01_RS18490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB01_RS18495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB01_RS18500	COG0789	Transcriptional regulator
PB01_RS18515	COG0577	efflux transmembrane transporter activity
PB01_RS18520	COG1136	(ABC) transporter
PB01_RS18525	COG0415	Belongs to the DNA photolyase family
PB01_RS18530	COG0415	Belongs to the DNA photolyase family
PB01_RS18535	COG0436	Aminotransferase
PB01_RS18540	COG0534	Mate efflux family protein
PB01_RS18555	COG0697	spore germination
PB01_RS18590	COG1086	Polysaccharide biosynthesis protein
PB01_RS18600	COG1120	ATPase activity
PB01_RS18605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS18610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB01_RS18615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB01_RS18655	COG3290	protein histidine kinase activity
PB01_RS18655	COG0840	transmembrane signaling receptor activity
PB01_RS18660	COG0572	uridine kinase
PB01_RS18675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PB01_RS18690	COG4720	Psort location CytoplasmicMembrane, score
PB01_RS18700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PB01_RS18705	COG0604	alcohol dehydrogenase
PB01_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS18705	COG3321	synthase
PB01_RS18720	COG1309	transcriptional regulator
PB01_RS18725	COG2814	Major facilitator Superfamily
PB01_RS18745	COG0166	Belongs to the GPI family
PB01_RS18750	COG0366	Alpha amylase catalytic
PB01_RS18755	COG1609	Transcriptional regulator
PB01_RS18775	COG1940	carbohydrate kinase activity
PB01_RS18780	COG0366	Alpha amylase catalytic
PB01_RS18790	COG2824	Alkylphosphonate utilization operon protein PhnA
PB01_RS18795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PB01_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS18815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PB01_RS18840	COG0179	Fumarylacetoacetate (FAA) hydrolase
PB01_RS18845	COG1116	anion transmembrane transporter activity
PB01_RS18845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PB01_RS18900	COG3327	negative regulation of DNA-templated transcription, initiation
PB01_RS18905	COG1024	Enoyl-CoA hydratase
PB01_RS18910	COG0183	Belongs to the thiolase family
PB01_RS18915	COG1250	3-hydroxyacyl-CoA dehydrogenase
PB01_RS18920	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS18925	COG1024	Enoyl-CoA hydratase
PB01_RS18930	COG1024	Enoyl-CoA hydratase
PB01_RS18955	COG3396	Phenylacetate-CoA oxygenase
PB01_RS18960	COG0492	ferredoxin-NADP+ reductase activity
PB01_RS18965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PB01_RS18970	COG2318	DinB family
PB01_RS18975	COG2309	aminopeptidase activity
PB01_RS18985	COG1653	transport
PB01_RS18990	COG1175	transmembrane transport
PB01_RS18995	COG0395	ABC-type sugar transport system, permease component
PB01_RS19010	COG1668	transmembrane transport
PB01_RS19015	COG4555	ABC transporter
PB01_RS19020	COG3279	Response regulator of the LytR AlgR family
PB01_RS19040	COG1316	TRANSCRIPTIONal
PB01_RS19085	COG2818	Glycosylase
PB01_RS19110	COG1522	sequence-specific DNA binding
PB01_RS19120	COG1309	transcriptional regulator
PB01_RS19150	COG1121	(ABC) transporter
PB01_RS19165	COG4122	O-methyltransferase activity
PB01_RS19175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PB01_RS19180	COG0733	neurotransmitter:sodium symporter activity
PB01_RS19200	COG3655	Transcriptional regulator
PB01_RS19295	COG2059	Chromate
PB01_RS19300	COG2059	Chromate
PB01_RS19310	COG4608	Belongs to the ABC transporter superfamily
PB01_RS19315	COG0444	Belongs to the ABC transporter superfamily
PB01_RS19325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS19335	COG1522	sequence-specific DNA binding
PB01_RS19340	COG0693	protein deglycase activity
PB01_RS19360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PB01_RS19365	COG5662	AntiSigma factor
PB01_RS19370	COG1595	DNA-templated transcription, initiation
PB01_RS19385	COG0372	Belongs to the citrate synthase family
PB01_RS19390	COG0583	DNA-binding transcription factor activity
PB01_RS19455	COG2194	sulfuric ester hydrolase activity
PB01_RS19465	COG0489	protein tyrosine kinase activity
PB01_RS19470	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB01_RS19480	COG2211	Major facilitator Superfamily
PB01_RS19490	COG0833	amino acid
PB01_RS19500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PB01_RS19510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PB01_RS19515	COG1122	ATPase activity
PB01_RS19520	COG1122	ATPase activity
PB01_RS19530	COG0202	RNA polymerase activity
PB01_RS19545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PB01_RS19550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PB01_RS19560	COG0201	protein transport
PB01_RS19585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PB01_RS19615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PB01_RS19645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PB01_RS19670	COG2056	Na+-H+ antiporter family
PB01_RS19680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PB01_RS19685	COG0049	tRNA binding
PB01_RS19695	COG1358	cellular component organization or biogenesis
PB01_RS19710	COG2813	Specifically methylates the guanine in position
PB01_RS19735	COG0250	Participates in transcription elongation, termination and antitermination
PB01_RS19740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PB01_RS19745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PB01_RS19755	COG3688	RNA-binding protein containing a PIN domain
PB01_RS19760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PB01_RS19775	COG1045	serine acetyltransferase
PB01_RS19795	COG4956	integral membrane protein (PIN domain superfamily)
PB01_RS19800	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PB01_RS19805	COG0542	response to heat
PB01_RS19810	COG3869	Catalyzes the specific phosphorylation of arginine residues in
PB01_RS19830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PB01_RS19835	COG1131	(ABC) transporter
PB01_RS19840	COG4608	Belongs to the ABC transporter superfamily
PB01_RS19845	COG0791	NLP P60 protein
PB01_RS19850	COG4948	Mandelate Racemase Muconate Lactonizing
PB01_RS19855	COG1619	proteins homologs of microcin C7 resistance protein MccF
PB01_RS19860	COG4166	transmembrane transport
PB01_RS19865	COG0444	Belongs to the ABC transporter superfamily
PB01_RS19870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB01_RS19875	COG0601	transmembrane transport
PB01_RS19880	COG2362	D-Aminopeptidase
PB01_RS19890	COG0598	Magnesium transport protein CorA
PB01_RS19895	COG1690	Belongs to the RtcB family
PB01_RS19910	COG1607	acyl-coa hydrolase
PB01_RS19925	COG3832	glyoxalase III activity
PB01_RS19945	COG1366	Belongs to the anti-sigma-factor antagonist family
PB01_RS19960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PB01_RS19975	COG1846	Transcriptional regulator
PB01_RS19980	COG2814	Major facilitator Superfamily
PB01_RS19985	COG2032	superoxide dismutase activity
PB01_RS19990	COG2340	Cysteine-rich secretory protein family
PB01_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
PB01_RS20015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB01_RS20020	COG0586	Pfam SNARE associated Golgi protein
PB01_RS20025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PB01_RS20030	COG0427	acetyl-CoA hydrolase
PB01_RS20035	COG3279	Response regulator of the LytR AlgR family
PB01_RS20055	COG2207	Transcriptional regulator
PB01_RS20055	COG3708	Transcriptional regulator
PB01_RS20080	COG0581	inorganic phosphate transmembrane transporter activity
PB01_RS20085	COG0573	inorganic phosphate transmembrane transporter activity
PB01_RS20120	COG0583	DNA-binding transcription factor activity
PB01_RS20125	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
PB01_RS20135	COG2843	Capsule synthesis protein
PB01_RS20165	COG1131	(ABC) transporter
PB01_RS20185	COG4211	Belongs to the binding-protein-dependent transport system permease family
PB01_RS20190	COG1129	ABC transporter
PB01_RS20200	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PB01_RS20205	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PB01_RS20210	COG1850	ribulose-bisphosphate carboxylase activity
PB01_RS20220	COG0235	Class ii aldolase
PB01_RS20225	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PB01_RS20230	COG0805	protein transport
PB01_RS20235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB01_RS20240	COG2200	EAL domain
PB01_RS20250	COG2329	Antibiotic biosynthesis monooxygenase
PB01_RS20255	COG1846	Transcriptional regulator
PB01_RS20260	COG2814	Major facilitator Superfamily
PB01_RS20275	COG1126	abc transporter atp-binding protein
PB01_RS20280	COG0765	amino acid transport
PB01_RS20300	COG3639	organic phosphonate transmembrane transporter activity
PB01_RS20315	COG0737	Belongs to the 5'-nucleotidase family
PB01_RS20350	COG3119	arylsulfatase activity
PB01_RS20360	COG0784	Response regulator, receiver
PB01_RS20365	COG4191	Histidine kinase
PB01_RS20370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB01_RS20375	COG4720	Psort location CytoplasmicMembrane, score
PB01_RS20405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PB01_RS20420	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PB01_RS20425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PB01_RS20435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PB01_RS20440	COG0745	RESPONSE REGULATOR receiver
PB01_RS20445	COG4191	Histidine kinase
PB01_RS20445	COG2205	protein histidine kinase activity
PB01_RS20445	COG0745	RESPONSE REGULATOR receiver
PB01_RS20460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB01_RS20470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PB01_RS20475	COG4853	Protein conserved in bacteria
PB01_RS20485	COG5002	protein histidine kinase activity
PB01_RS20490	COG0745	RESPONSE REGULATOR receiver
PB01_RS20495	COG0739	heme binding
PB01_RS20505	COG0305	Participates in initiation and elongation during chromosome replication
PB01_RS20515	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PB01_RS20520	COG4241	membrane
PB01_RS20525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PB01_RS20535	COG0360	Binds together with S18 to 16S ribosomal RNA
PB01_RS20550	COG0012	GTP binding
PB01_RS20555	COG4481	Protein conserved in bacteria
PB01_RS20560	COG0668	transmembrane transport
PB01_RS20570	COG1811	Na channel or pump
PB01_RS20575	COG1475	DNA binding
PB01_RS20580	COG1192	Involved in chromosome partitioning
PB01_RS20605	COG1847	R3H domain protein
PB01_RS20610	COG0706	membrane insertase activity
PB01_RS20615	COG0594	ribonuclease P activity
PB01_RS20620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PB01_RS20655	COG2946	Replication initiation factor
PB01_RS20660	COG0860	N-Acetylmuramoyl-L-alanine amidase