locus-tag	class	description
PING_RS00040	COG3335	DDE superfamily endonuclease
PING_RS00050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PING_RS00055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PING_RS00065	COG0018	arginyl-trna synthetase
PING_RS00075	COG0210	DNA helicase
PING_RS00080	COG1011	Hydrolase
PING_RS00085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PING_RS00215	COG1181	Belongs to the D-alanine--D-alanine ligase family
PING_RS00235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PING_RS00240	COG0019	diaminopimelate decarboxylase activity
PING_RS00250	COG1965	Belongs to the frataxin family
PING_RS00260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PING_RS00270	COG4221	oxidoreductase activity
PING_RS00275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PING_RS00280	COG4521	taurine ABC transporter
PING_RS00285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PING_RS00290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PING_RS00300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PING_RS00310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PING_RS00315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PING_RS00320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PING_RS00325	COG2003	Belongs to the UPF0758 family
PING_RS00330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PING_RS00335	COG0756	dUTP diphosphatase activity
PING_RS00340	COG1309	transcriptional regulator
PING_RS00345	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PING_RS00350	COG3072	Adenylate cyclase
PING_RS00360	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PING_RS00370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PING_RS00375	COG1595	DNA-templated transcription, initiation
PING_RS00420	COG3084	Protein conserved in bacteria
PING_RS00425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PING_RS00430	COG0009	L-threonylcarbamoyladenylate synthase
PING_RS00435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PING_RS00440	COG0551	DNA topoisomerase type I activity
PING_RS00445	COG2922	Belongs to the Smg family
PING_RS00450	COG0758	DNA mediated transformation
PING_RS00460	COG0242	peptide deformylase activity
PING_RS00465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PING_RS00470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PING_RS00470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PING_RS00475	COG0569	domain protein
PING_RS00480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PING_RS00485	COG1322	Protein conserved in bacteria
PING_RS00495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PING_RS00500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PING_RS00510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS00510	COG2213	PTS system mannitol-specific
PING_RS00515	COG0246	Mannitol dehydrogenase
PING_RS00520	COG3722	fumarate hydratase activity
PING_RS00525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PING_RS00535	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PING_RS00540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PING_RS00545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PING_RS00550	COG3031	protein transport across the cell outer membrane
PING_RS00555	COG1450	Type ii and iii secretion system protein
PING_RS00560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PING_RS00565	COG1459	type II secretion system
PING_RS00570	COG2165	general secretion pathway protein
PING_RS00575	COG2165	general secretion pathway protein
PING_RS00580	COG2165	general secretion pathway protein
PING_RS00590	COG3156	type II secretion system protein K
PING_RS00600	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PING_RS00610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PING_RS00615	COG1999	signal sequence binding
PING_RS00620	COG0534	Mate efflux family protein
PING_RS00630	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PING_RS00635	COG1410	methionine synthase
PING_RS00635	COG0646	methionine synthase
PING_RS00640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PING_RS00645	COG3217	Mosc domain protein beta barrel domain protein
PING_RS00645	COG0633	Ferredoxin
PING_RS00650	COG1803	Methylglyoxal synthase
PING_RS00660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PING_RS00665	COG0494	nUDIX hydrolase
PING_RS00695	COG0589	response to stress
PING_RS00715	COG0800	Aldolase
PING_RS00720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PING_RS00725	COG1904	glucuronate isomerase
PING_RS00730	COG0246	Mannitol dehydrogenase
PING_RS00740	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PING_RS00750	COG1312	Catalyzes the dehydration of D-mannonate
PING_RS00760	COG2186	Transcriptional regulator
PING_RS00785	COG1061	Type III restriction enzyme res subunit
PING_RS00815	COG1011	Hydrolase
PING_RS00840	COG1011	Hydrolase
PING_RS00845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PING_RS00875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PING_RS00880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PING_RS00890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PING_RS00895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PING_RS00900	COG0180	Tryptophanyl-tRNA synthetase
PING_RS00905	COG0346	lactoylglutathione lyase activity
PING_RS00915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PING_RS00920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PING_RS00925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PING_RS00930	COG1968	undecaprenyl-diphosphatase activity
PING_RS00935	COG0390	transport system, permease component
PING_RS00940	COG0617	tRNA 3'-terminal CCA addition
PING_RS00945	COG3267	Type II secretory pathway component ExeA
PING_RS00945	COG3409	Peptidoglycan-binding domain 1 protein
PING_RS00960	COG0306	phosphate transporter
PING_RS00965	COG1392	Phosphate transport regulator
PING_RS00970	COG3025	triphosphatase activity
PING_RS00990	COG3789	protein conserved in bacteria
PING_RS00995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PING_RS01000	COG1560	Kdo2-lipid A biosynthetic process
PING_RS01005	COG0318	PFAM AMP-dependent synthetase and ligase
PING_RS01010	COG1441	menaquinone biosynthetic process
PING_RS01015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PING_RS01020	COG0305	Participates in initiation and elongation during chromosome replication
PING_RS01025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PING_RS01030	COG2937	Belongs to the GPAT DAPAT family
PING_RS01040	COG1739	Uncharacterized protein family UPF0029
PING_RS01045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PING_RS01050	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
PING_RS01055	COG0514	ATP-dependent DNA helicase (RecQ)
PING_RS01065	COG3593	DNA synthesis involved in DNA repair
PING_RS01075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PING_RS01090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PING_RS01095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PING_RS01105	COG3078	GTPase activator activity
PING_RS01115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PING_RS01130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PING_RS01135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PING_RS01140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PING_RS01145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PING_RS01145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PING_RS01150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PING_RS01155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PING_RS01155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PING_RS01180	COG5001	Diguanylate cyclase
PING_RS01185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PING_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
PING_RS01195	COG1070	Carbohydrate kinase
PING_RS01200	COG0425	Belongs to the sulfur carrier protein TusA family
PING_RS01205	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PING_RS01220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PING_RS01230	COG0137	argininosuccinate synthase activity
PING_RS01240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PING_RS01280	COG0582	viral genome integration into host DNA
PING_RS01315	COG3547	Transposase (IS116 IS110 IS902 family)
PING_RS01430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PING_RS01440	COG2176	DNA-directed DNA polymerase activity
PING_RS01455	COG2866	Carboxypeptidase
PING_RS01475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PING_RS01480	COG5001	Diguanylate cyclase
PING_RS01480	COG3447	MASE1 domain protein
PING_RS01480	COG5002	protein histidine kinase activity
PING_RS01495	COG2207	Transcriptional regulator
PING_RS01500	COG4303	Ethanolamine ammonia lyase large subunit
PING_RS01505	COG4302	ethanolamine ammonia-lyase activity
PING_RS01510	COG0531	amino acid
PING_RS01540	COG0709	Synthesizes selenophosphate from selenide and ATP
PING_RS01545	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PING_RS01550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PING_RS01555	COG0287	Prephenate dehydrogenase
PING_RS01555	COG1605	Chorismate mutase
PING_RS01560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PING_RS01565	COG4166	transmembrane transport
PING_RS01570	COG4174	ABC transporter (Permease)
PING_RS01575	COG4239	(ABC) transporter, permease
PING_RS01580	COG4172	Belongs to the ABC transporter superfamily
PING_RS01585	COG0741	lytic transglycosylase activity
PING_RS01595	COG1438	arginine binding
PING_RS01600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PING_RS01605	COG0039	L-malate dehydrogenase activity
PING_RS01610	COG1648	precorrin-2 dehydrogenase activity
PING_RS01610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PING_RS01650	COG3437	response regulator, receiver
PING_RS01650	COG0784	Response regulator, receiver
PING_RS01655	COG2133	pyrroloquinoline quinone binding
PING_RS01680	COG0358	DNA primase activity
PING_RS01685	COG1610	YqeY-like protein
PING_RS01690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PING_RS01695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PING_RS01715	COG0805	protein transport
PING_RS01720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PING_RS01725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PING_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PING_RS01740	COG2226	methyltransferase
PING_RS01745	COG0166	Belongs to the GPI family
PING_RS01760	COG0859	PFAM glycosyl transferase family 9
PING_RS01765	COG0463	Glycosyl transferase, family 2
PING_RS01770	COG0859	PFAM glycosyl transferase family 9
PING_RS01775	COG3642	lipopolysaccharide core region biosynthetic process
PING_RS01785	COG1519	Transferase
PING_RS01795	COG0859	PFAM glycosyl transferase family 9
PING_RS01800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PING_RS01805	COG0438	transferase activity, transferring glycosyl groups
PING_RS01810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PING_RS01820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PING_RS01825	COG1869	D-ribose catabolic process
PING_RS01830	COG1129	ABC transporter
PING_RS01835	COG1172	Belongs to the binding-protein-dependent transport system permease family
PING_RS01840	COG1879	ABC-type sugar transport system periplasmic component
PING_RS01845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PING_RS01850	COG1609	Transcriptional regulator
PING_RS01855	COG0129	dihydroxy-acid dehydratase activity
PING_RS01860	COG3978	acetolactate synthase activity
PING_RS01875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PING_RS01880	COG0596	Alpha beta hydrolase
PING_RS01885	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PING_RS01895	COG1169	isochorismate synthase
PING_RS01900	COG1169	isochorismate synthase
PING_RS01905	COG1575	Belongs to the MenA family. Type 1 subfamily
PING_RS01910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PING_RS01915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PING_RS01925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PING_RS01930	COG2104	thiamine diphosphate biosynthetic process
PING_RS01935	COG2022	thiamine diphosphate biosynthetic process
PING_RS01945	COG2501	S4 domain
PING_RS01960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PING_RS01970	COG0126	phosphoglycerate kinase activity
PING_RS02005	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PING_RS02010	COG1194	a g-specific adenine glycosylase
PING_RS02015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PING_RS02020	COG2310	stress, protein
PING_RS02025	COG4520	surface antigen
PING_RS02035	COG0393	Putative heavy-metal-binding
PING_RS02055	COG4143	(ABC) transporter
PING_RS02060	COG1178	ABC-type Fe3 transport system permease component
PING_RS02065	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PING_RS02075	COG3089	Belongs to the UPF0270 family
PING_RS02080	COG0288	reversible hydration of carbon dioxide
PING_RS02090	COG0606	chelatase, subunit chli
PING_RS02095	COG0525	valine-tRNA ligase activity
PING_RS02100	COG2927	DNA polymerase III (CHI subunit)
PING_RS02105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PING_RS02110	COG0795	lipopolysaccharide-transporting ATPase activity
PING_RS02115	COG0795	lipopolysaccharide-transporting ATPase activity
PING_RS02130	COG0582	viral genome integration into host DNA
PING_RS02200	COG0765	amino acid transport
PING_RS02205	COG0765	amino acid transport
PING_RS02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PING_RS02215	COG0251	oxidation-reduction process
PING_RS02245	COG2204	response regulator
PING_RS02270	COG4191	Histidine kinase
PING_RS02275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PING_RS02280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PING_RS02320	COG0438	transferase activity, transferring glycosyl groups
PING_RS02430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PING_RS02450	COG0356	it plays a direct role in the translocation of protons across the membrane
PING_RS02460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PING_RS02465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PING_RS02480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PING_RS02505	COG4969	Belongs to the N-Me-Phe pilin family
PING_RS02515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PING_RS02520	COG1459	type II secretion system
PING_RS02550	COG1846	Transcriptional regulator
PING_RS02550	COG1940	carbohydrate kinase activity
PING_RS02555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PING_RS02560	COG0363	glucosamine-6-phosphate deaminase activity
PING_RS02565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PING_RS02565	COG1263	PTS System
PING_RS02565	COG2190	(PTS) system
PING_RS02570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PING_RS02610	COG0328	RNA-DNA hybrid ribonuclease activity
PING_RS02615	COG2226	methyltransferase
PING_RS02620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PING_RS02625	COG1388	LysM domain
PING_RS02625	COG0741	lytic transglycosylase activity
PING_RS02640	COG0494	nUDIX hydrolase
PING_RS02650	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PING_RS02655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PING_RS02660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PING_RS02665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PING_RS02700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PING_RS02710	COG1408	metallophosphoesterase
PING_RS02715	COG0443	Heat shock 70 kDa protein
PING_RS02730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PING_RS02740	COG0435	Glutathione S-transferase
PING_RS02745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PING_RS02745	COG1263	PTS System
PING_RS02750	COG0366	Alpha amylase catalytic
PING_RS02755	COG0142	geranyltranstransferase activity
PING_RS02760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PING_RS02765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PING_RS02770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PING_RS02780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PING_RS02785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PING_RS02790	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PING_RS02795	COG4535	Mg2 and Co2 transporter CorC
PING_RS02800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PING_RS02805	COG1702	phosphate starvation-inducible protein PhoH
PING_RS02810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PING_RS02815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PING_RS02820	COG0281	malic enzyme
PING_RS02825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PING_RS02830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PING_RS02835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PING_RS02845	COG0668	transmembrane transport
PING_RS02875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PING_RS02880	COG0444	Belongs to the ABC transporter superfamily
PING_RS02885	COG4608	Belongs to the ABC transporter superfamily
PING_RS02900	COG1609	Transcriptional regulator
PING_RS02960	COG0601	transmembrane transport
PING_RS02965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PING_RS02970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PING_RS02975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PING_RS02980	COG0564	pseudouridine synthase activity
PING_RS02985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PING_RS03020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PING_RS03040	COG1131	(ABC) transporter
PING_RS03045	COG0842	Transport permease protein
PING_RS03050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PING_RS03055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PING_RS03065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PING_RS03070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PING_RS03075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PING_RS03080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PING_RS03085	COG0617	tRNA 3'-terminal CCA addition
PING_RS03090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PING_RS03100	COG1643	Atp-dependent helicase
PING_RS03110	COG1742	UPF0060 membrane protein
PING_RS03130	COG0205	6-phosphofructokinase activity
PING_RS03140	COG1280	lysine exporter protein (LysE YggA)
PING_RS03150	COG3097	Belongs to the UPF0267 family
PING_RS03155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PING_RS03170	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PING_RS03175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PING_RS03180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PING_RS03185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PING_RS03205	COG0006	proline dipeptidase activity
PING_RS03210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PING_RS03220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PING_RS03225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PING_RS03250	COG4176	ABC-type proline glycine betaine transport system permease component
PING_RS03255	COG4175	Glycine betaine
PING_RS03260	COG0517	IMP dehydrogenase activity
PING_RS03260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PING_RS03285	COG0742	ribosomal rna small subunit methyltransferase
PING_RS03290	COG0552	protein localization to endoplasmic reticulum
PING_RS03295	COG2884	Cell division ATP-binding protein ftsE
PING_RS03300	COG2177	Part of the ABC transporter FtsEX involved in
PING_RS03315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PING_RS03320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PING_RS03330	COG1959	2 iron, 2 sulfur cluster binding
PING_RS03340	COG1770	oligopeptidase
PING_RS03365	COG0481	GTPase activity
PING_RS03375	COG0571	ribonuclease III activity
PING_RS03385	COG1381	Involved in DNA repair and RecF pathway recombination
PING_RS03390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PING_RS03395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PING_RS03400	COG1929	Belongs to the glycerate kinase type-1 family
PING_RS03420	COG2030	dehydratase
PING_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
PING_RS03425	COG3396	Phenylacetate-CoA oxygenase
PING_RS03430	COG3460	Phenylacetate-CoA oxygenase
PING_RS03435	COG3396	Phenylacetate-CoA oxygenase
PING_RS03440	COG2151	metal-sulfur cluster biosynthetic enzyme
PING_RS03445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PING_RS03450	COG1024	Enoyl-CoA hydratase
PING_RS03455	COG1024	Enoyl-CoA hydratase
PING_RS03460	COG1250	3-hydroxyacyl-CoA dehydrogenase
PING_RS03465	COG2050	protein possibly involved in aromatic compounds catabolism
PING_RS03470	COG0183	Belongs to the thiolase family
PING_RS03475	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PING_RS03480	COG3327	negative regulation of DNA-templated transcription, initiation
PING_RS03490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PING_RS03500	COG3956	TIGRFAM MazG family protein
PING_RS03510	COG0504	CTP synthase activity
PING_RS03515	COG0148	phosphopyruvate hydratase activity
PING_RS03525	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PING_RS03530	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PING_RS03540	COG0585	pseudouridine synthase activity
PING_RS03545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PING_RS03550	COG1388	LysM domain
PING_RS03550	COG4942	peptidase
PING_RS03555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PING_RS03585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PING_RS03595	COG0626	cystathionine gamma-synthase activity
PING_RS03600	COG2992	FlgJ-related protein
PING_RS03605	COG1435	thymidine kinase activity
PING_RS03635	COG1132	(ABC) transporter
PING_RS03640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PING_RS03655	COG0494	nUDIX hydrolase
PING_RS03660	COG0500	methyltransferase
PING_RS03665	COG2226	methyltransferase
PING_RS03670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PING_RS03675	COG3047	cAMP biosynthetic process
PING_RS03685	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PING_RS03690	COG2116	formate transmembrane transporter activity
PING_RS03695	COG0515	serine threonine protein kinase
PING_RS03695	COG2815	serine threonine protein kinase
PING_RS03705	COG2154	pterin-4-alpha-carbinolamine dehydratase
PING_RS03715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PING_RS03720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PING_RS03725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PING_RS03730	COG1489	DNA binding
PING_RS03750	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PING_RS03755	COG2962	Rard protein
PING_RS03760	COG0632	four-way junction helicase activity
PING_RS03765	COG2255	four-way junction helicase activity
PING_RS03775	COG1294	oxidase, subunit
PING_RS03780	COG4890	Cyd operon protein YbgT
PING_RS03785	COG0824	Thioesterase
PING_RS03790	COG0811	peptide transport
PING_RS03800	COG3064	Membrane
PING_RS03805	COG0823	Involved in the tonB-independent uptake of proteins
PING_RS03810	COG2885	chlorophyll binding
PING_RS03845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PING_RS03850	COG4807	Protein conserved in bacteria
PING_RS03855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PING_RS03860	COG4660	Part of a membrane complex involved in electron transport
PING_RS03875	COG4658	electron transport chain
PING_RS03885	COG2878	Part of a membrane complex involved in electron transport
PING_RS03890	COG4657	Part of a membrane complex involved in electron transport
PING_RS03905	COG0602	queuosine metabolic process
PING_RS03910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PING_RS03915	COG0542	response to heat
PING_RS03920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PING_RS03925	COG0271	Belongs to the BolA IbaG family
PING_RS03930	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PING_RS03940	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PING_RS03945	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PING_RS03950	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PING_RS03955	COG2871	sodium ion transport
PING_RS03960	COG1477	protein flavinylation
PING_RS03970	COG1671	Belongs to the UPF0178 family
PING_RS03975	COG1278	Cold shock
PING_RS03980	COG0717	Belongs to the dCTP deaminase family
PING_RS04040	COG1051	belongs to the nudix hydrolase family
PING_RS04050	COG5433	transposase activity
PING_RS04065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PING_RS04070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PING_RS04095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PING_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PING_RS04110	COG0463	Glycosyl transferase, family 2
PING_RS04115	COG5433	transposase activity
PING_RS04145	COG5433	transposase activity
PING_RS04155	COG1086	Polysaccharide biosynthesis protein
PING_RS04175	COG5433	transposase activity
PING_RS04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PING_RS04185	COG0175	sulfate reduction
PING_RS04195	COG2895	sulfate adenylyltransferase (ATP) activity
PING_RS04200	COG0471	metal ion transport
PING_RS04200	COG3273	potassium ion transport
PING_RS04205	COG0529	Catalyzes the synthesis of activated sulfate
PING_RS04220	COG0724	RNA recognition motif
PING_RS04230	COG5433	transposase activity
PING_RS04235	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PING_RS04240	COG0084	hydrolase, TatD family'
PING_RS04245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PING_RS04250	COG1534	Rna-binding protein
PING_RS04255	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PING_RS04260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PING_RS04265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PING_RS04270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PING_RS04275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PING_RS04285	COG0779	Required for maturation of 30S ribosomal subunits
PING_RS04290	COG0195	Participates in both transcription termination and antitermination
PING_RS04295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PING_RS04295	COG3064	Membrane
PING_RS04300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PING_RS04305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PING_RS04320	COG4120	Belongs to the binding-protein-dependent transport system permease family
PING_RS04325	COG1122	ATPase activity
PING_RS04330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PING_RS04335	COG1185	polyribonucleotide nucleotidyltransferase activity
PING_RS04340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PING_RS04345	COG0163	prenyltransferase activity
PING_RS04380	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PING_RS04400	COG3098	single-species biofilm formation
PING_RS04410	COG5002	protein histidine kinase activity
PING_RS04420	COG0513	Belongs to the DEAD box helicase family
PING_RS04430	COG2814	Major facilitator Superfamily
PING_RS04435	COG3030	protein affecting phage T7 exclusion by the F plasmid
PING_RS04450	COG0459	protein refolding
PING_RS04490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PING_RS04495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PING_RS04500	COG2897	thiosulfate sulfurtransferase activity
PING_RS04520	COG2960	long-chain fatty acid transporting porin activity
PING_RS04535	COG1166	arginine decarboxylase activity
PING_RS04540	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PING_RS04555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PING_RS04560	COG0038	chloride channel
PING_RS04565	COG0316	Belongs to the HesB IscA family
PING_RS04585	COG0425	Belongs to the sulfur carrier protein TusA family
PING_RS04585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PING_RS04590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PING_RS04590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PING_RS04595	COG0735	belongs to the Fur family
PING_RS04600	COG0716	FMN binding
PING_RS04620	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PING_RS04625	COG0033	Phosphoglucomutase
PING_RS04630	COG0058	SHG alpha-glucan phosphorylase activity
PING_RS04640	COG0513	Belongs to the DEAD box helicase family
PING_RS04670	COG2056	Na+-H+ antiporter family
PING_RS04705	COG2195	Cleaves the N-terminal amino acid of tripeptides
PING_RS04715	COG0505	Belongs to the CarA family
PING_RS04720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PING_RS04730	COG2333	competence protein COMEC
PING_RS04730	COG0658	competence protein
PING_RS04735	COG1132	(ABC) transporter
PING_RS04740	COG1663	tetraacyldisaccharide 4'-kinase activity
PING_RS04745	COG2835	tetraacyldisaccharide 4'-kinase activity
PING_RS04750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PING_RS04765	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PING_RS04770	COG1349	DNA-binding transcription factor activity
PING_RS04780	COG0193	aminoacyl-tRNA hydrolase activity
PING_RS04785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PING_RS04790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PING_RS04795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PING_RS04800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PING_RS04805	COG0497	DNA recombination
PING_RS04810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PING_RS04815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PING_RS04820	COG0443	Heat shock 70 kDa protein
PING_RS04825	COG0484	heat shock protein binding
PING_RS04830	COG0545	Peptidyl-prolyl cis-trans isomerase
PING_RS04835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PING_RS04850	COG1469	GTP cyclohydrolase I activity
PING_RS04855	COG2198	Histidine kinase
PING_RS04855	COG5002	protein histidine kinase activity
PING_RS04855	COG0784	Response regulator, receiver
PING_RS04865	COG4783	chaperone-mediated protein folding
PING_RS04880	COG0628	permease
PING_RS04885	COG0628	permease
PING_RS04890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PING_RS04895	COG0589	response to stress
PING_RS04900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PING_RS04915	COG2217	Heavy metal translocating P-type atpase
PING_RS04925	COG2010	Cytochrome c
PING_RS04940	COG3278	Belongs to the heme-copper respiratory oxidase family
PING_RS04970	COG3220	belongs to the UPF0276 family
PING_RS05055	COG4221	oxidoreductase activity
PING_RS05060	COG1022	Amp-dependent synthetase and ligase
PING_RS05090	COG0589	response to stress
PING_RS05095	COG0589	response to stress
PING_RS05100	COG0326	Molecular chaperone. Has ATPase activity
PING_RS05105	COG0563	adenylate kinase activity
PING_RS05110	COG0791	NLP P60 protein
PING_RS05115	COG0589	response to stress
PING_RS05120	COG2850	peptidyl-arginine hydroxylation
PING_RS05125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PING_RS05130	COG2915	High frequency lysogenization protein hflD homolog
PING_RS05135	COG0482	sulfurtransferase activity
PING_RS05145	COG0659	secondary active sulfate transmembrane transporter activity
PING_RS05155	COG0517	IMP dehydrogenase activity
PING_RS05165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PING_RS05175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PING_RS05180	COG1263	PTS System
PING_RS05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PING_RS05185	COG1609	Transcriptional regulator
PING_RS05190	COG1621	beta-fructofuranosidase activity
PING_RS05200	COG1119	ATPase activity
PING_RS05240	COG3722	fumarate hydratase activity
PING_RS05245	COG2213	PTS system mannitol-specific
PING_RS05245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS05255	COG2205	protein histidine kinase activity
PING_RS05260	COG0745	RESPONSE REGULATOR receiver
PING_RS05265	COG4221	oxidoreductase activity
PING_RS05290	COG1595	DNA-templated transcription, initiation
PING_RS05295	COG3806	Anti-sigma factor
PING_RS05315	COG4221	oxidoreductase activity
PING_RS05330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PING_RS05350	COG0069	glutamate synthase activity
PING_RS05350	COG0070	glutamate synthase
PING_RS05350	COG0067	glutamate synthase
PING_RS05360	COG1757	Na H antiporter
PING_RS05370	COG1279	arginine transmembrane transporter activity
PING_RS05380	COG0488	(ABC) transporter
PING_RS05385	COG0318	PFAM AMP-dependent synthetase and ligase
PING_RS05390	COG3360	Dodecin
PING_RS05395	COG2840	Smr protein MutS2
PING_RS05400	COG2890	protein-(glutamine-N5) methyltransferase activity
PING_RS05405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PING_RS05425	COG2815	serine threonine protein kinase
PING_RS05425	COG0515	serine threonine protein kinase
PING_RS05430	COG2223	nitrite transmembrane transporter activity
PING_RS05435	COG2146	nitrite reductase [NAD(P)H] activity
PING_RS05440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PING_RS05445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PING_RS05445	COG1648	precorrin-2 dehydrogenase activity
PING_RS05450	COG0243	molybdopterin cofactor binding
PING_RS05460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PING_RS05465	COG2986	histidine ammonia-lyase
PING_RS05470	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PING_RS05475	COG0010	Belongs to the arginase family
PING_RS05480	COG1228	amidohydrolase
PING_RS05490	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PING_RS05495	COG0604	alcohol dehydrogenase
PING_RS05510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PING_RS05525	COG0542	response to heat
PING_RS05530	COG2353	YceI-like domain
PING_RS05535	COG3038	cytochrome b561
PING_RS05555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PING_RS05560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PING_RS05570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PING_RS05580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PING_RS05585	COG2171	N-acyltransferase activity
PING_RS05590	COG2350	Protein conserved in bacteria
PING_RS05595	COG2917	probably involved in intracellular septation
PING_RS05600	COG0159	tryptophan synthase activity
PING_RS05605	COG0133	tryptophan synthase activity
PING_RS05610	COG0135	phosphoribosylanthranilate isomerase activity
PING_RS05610	COG0134	indole-3-glycerol-phosphate synthase activity
PING_RS05615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PING_RS05620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PING_RS05620	COG0512	Glutamine amidotransferase of anthranilate synthase
PING_RS05625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PING_RS05635	COG0009	L-threonylcarbamoyladenylate synthase
PING_RS05650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PING_RS05660	COG1346	cytolysis
PING_RS05665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PING_RS05670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PING_RS05690	COG1393	Belongs to the ArsC family
PING_RS05695	COG2983	Belongs to the UPF0260 family
PING_RS05700	COG2951	lytic endotransglycosylase activity
PING_RS05705	COG3100	YcgL domain-containing protein
PING_RS05710	COG0850	regulation of cytokinetic process
PING_RS05715	COG2894	cell division
PING_RS05720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PING_RS05725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PING_RS05735	COG0556	nucleotide-excision repair
PING_RS05740	COG0424	maF-like protein
PING_RS05745	COG1399	metal-binding, possibly nucleic acid-binding protein
PING_RS05750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PING_RS05755	COG0416	fatty acid biosynthetic process
PING_RS05760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PING_RS05775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PING_RS05780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PING_RS05785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PING_RS05790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PING_RS05805	COG0084	hydrolase, TatD family'
PING_RS05825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PING_RS05830	COG0602	queuosine metabolic process
PING_RS05835	COG1643	Atp-dependent helicase
PING_RS05845	COG0788	formyltetrahydrofolate deformylase activity
PING_RS05850	COG3012	SEC-C Motif Domain Protein
PING_RS05855	COG0367	asparagine synthase
PING_RS05860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PING_RS05860	COG4651	solute:proton antiporter activity
PING_RS05885	COG1879	ABC-type sugar transport system periplasmic component
PING_RS05895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PING_RS05910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PING_RS05915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PING_RS05920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PING_RS05935	COG2203	Gaf domain
PING_RS05935	COG5001	Diguanylate cyclase
PING_RS05935	COG4251	negative regulation of phosphorylation
PING_RS05935	COG3706	GGDEF domain
PING_RS05940	COG1077	Cell shape determining protein MreB Mrl
PING_RS05945	COG1792	Involved in formation and maintenance of cell shape
PING_RS05950	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PING_RS05960	COG1530	ribonuclease E activity
PING_RS05970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PING_RS05975	COG0312	modulator of DNA gyrase
PING_RS05985	COG3028	Belongs to the UPF0307 family
PING_RS05990	COG0312	modulator of DNA gyrase
PING_RS05995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PING_RS06000	COG0772	Belongs to the SEDS family
PING_RS06005	COG0768	penicillin binding
PING_RS06010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PING_RS06015	COG0799	negative regulation of ribosome biogenesis
PING_RS06020	COG2001	Belongs to the MraZ family
PING_RS06025	COG0275	rRNA processing
PING_RS06030	COG3116	cell division
PING_RS06035	COG0768	penicillin binding
PING_RS06045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PING_RS06050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PING_RS06055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PING_RS06060	COG0772	Belongs to the SEDS family
PING_RS06065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PING_RS06070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PING_RS06075	COG1181	Belongs to the D-alanine--D-alanine ligase family
PING_RS06080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PING_RS06085	COG0849	cell division
PING_RS06090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PING_RS06095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PING_RS06105	COG0653	protein targeting
PING_RS06110	COG0494	nUDIX hydrolase
PING_RS06115	COG1793	dna ligase
PING_RS06120	COG0157	Belongs to the NadC ModD family
PING_RS06130	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PING_RS06135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PING_RS06150	COG0023	Translation Initiation Factor
PING_RS06160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PING_RS06175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PING_RS06180	COG0124	histidyl-tRNA synthetase
PING_RS06185	COG2976	Protein conserved in bacteria
PING_RS06190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PING_RS06195	COG1160	GTP binding
PING_RS06210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PING_RS06215	COG0792	nuclease activity
PING_RS06220	COG3107	peptidoglycan biosynthetic process
PING_RS06225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PING_RS06245	COG3274	enterobacterial common antigen metabolic process
PING_RS06260	COG2801	Transposase and inactivated derivatives
PING_RS06285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PING_RS06300	COG0495	leucyl-tRNA aminoacylation
PING_RS06315	COG2197	response regulator
PING_RS06320	COG0322	excinuclease ABC activity
PING_RS06325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PING_RS06345	COG0745	RESPONSE REGULATOR receiver
PING_RS06370	COG3287	FIST C domain
PING_RS06370	COG2199	diguanylate cyclase activity
PING_RS06370	COG2200	EAL domain
PING_RS06375	COG2200	EAL domain
PING_RS06375	COG2199	diguanylate cyclase activity
PING_RS06375	COG3287	FIST C domain
PING_RS06380	COG2199	diguanylate cyclase activity
PING_RS06380	COG2200	EAL domain
PING_RS06380	COG3287	FIST C domain
PING_RS06405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PING_RS06405	COG1024	Enoyl-CoA hydratase
PING_RS06415	COG0298	carbon dioxide binding
PING_RS06425	COG0375	protein maturation
PING_RS06435	COG3259	Nickel-dependent hydrogenase
PING_RS06445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PING_RS06450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PING_RS06500	COG0745	RESPONSE REGULATOR receiver
PING_RS06505	COG0642	Histidine kinase
PING_RS06510	COG0697	spore germination
PING_RS06525	COG0443	Heat shock 70 kDa protein
PING_RS06535	COG0754	glutathionylspermidine amidase activity
PING_RS06545	COG3437	response regulator, receiver
PING_RS06545	COG0784	Response regulator, receiver
PING_RS06560	COG3273	potassium ion transport
PING_RS06560	COG0471	metal ion transport
PING_RS06570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PING_RS06575	COG4702	Belongs to the UPF0303 family
PING_RS06580	COG0673	inositol 2-dehydrogenase activity
PING_RS06595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PING_RS06610	COG3852	Histidine kinase
PING_RS06615	COG3279	Response regulator of the LytR AlgR family
PING_RS06710	COG1358	cellular component organization or biogenesis
PING_RS06735	COG0083	homoserine kinase activity
PING_RS06740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PING_RS06745	COG1946	Acyl-CoA thioesterase
PING_RS06750	COG4974	Belongs to the 'phage' integrase family
PING_RS06760	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PING_RS06770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PING_RS06785	COG1678	Uncharacterized ACR, COG1678
PING_RS06790	COG0189	ligase activity
PING_RS06795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PING_RS06805	COG2966	Psort location CytoplasmicMembrane, score
PING_RS06810	COG3610	response to peptide
PING_RS06815	COG0653	protein targeting
PING_RS06830	COG1061	Type III restriction enzyme res subunit
PING_RS06835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PING_RS06840	COG1744	ABC transporter substrate-binding protein PnrA-like
PING_RS06845	COG3845	ABC transporter
PING_RS06855	COG1079	Belongs to the binding-protein-dependent transport system permease family
PING_RS06860	COG0826	peptidase U32
PING_RS06900	COG0420	3'-5' exonuclease activity
PING_RS06905	COG0419	ATPase involved in DNA repair
PING_RS06940	COG3258	Cytochrome c
PING_RS06945	COG2863	cytochrome
PING_RS06975	COG0659	secondary active sulfate transmembrane transporter activity
PING_RS06980	COG0205	6-phosphofructokinase activity
PING_RS06990	COG0564	pseudouridine synthase activity
PING_RS06995	COG0708	Exodeoxyribonuclease III
PING_RS07005	COG0483	inositol monophosphate 1-phosphatase activity
PING_RS07015	COG1959	2 iron, 2 sulfur cluster binding
PING_RS07020	COG1104	cysteine desulfurase activity
PING_RS07025	COG0822	iron-sulfur transferase activity
PING_RS07035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PING_RS07040	COG0443	Heat shock 70 kDa protein
PING_RS07055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PING_RS07060	COG1940	carbohydrate kinase activity
PING_RS07070	COG1752	Esterase of the alpha-beta hydrolase superfamily
PING_RS07075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PING_RS07080	COG0121	glutamine amidotransferase
PING_RS07085	COG4335	DNA alkylation repair
PING_RS07090	COG1301	dicarboxylic acid transport
PING_RS07100	COG2217	Heavy metal translocating P-type atpase
PING_RS07110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PING_RS07115	COG3335	DDE superfamily endonuclease
PING_RS07155	COG1320	monovalent cation:proton antiporter activity
PING_RS07160	COG2212	antiporter activity
PING_RS07165	COG1863	multisubunit Na H antiporter MnhE subunit
PING_RS07175	COG0651	ATP synthesis coupled electron transport
PING_RS07180	COG1006	Multisubunit Na H antiporter MnhC subunit
PING_RS07185	COG2111	Na H antiporter
PING_RS07185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PING_RS07195	COG3335	DDE superfamily endonuclease
PING_RS07220	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
PING_RS07240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PING_RS07250	COG2205	protein histidine kinase activity
PING_RS07280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PING_RS07285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PING_RS07285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PING_RS07295	COG2217	Heavy metal translocating P-type atpase
PING_RS07315	COG0789	Transcriptional regulator
PING_RS07345	COG2095	MarC family integral membrane protein
PING_RS07350	COG3314	Sporulation integral membrane protein YlbJ
PING_RS07400	COG0179	Fumarylacetoacetate (FAA) hydrolase
PING_RS07405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PING_RS07410	COG0072	phenylalanine-tRNA ligase activity
PING_RS07410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PING_RS07415	COG0776	regulation of translation
PING_RS07420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PING_RS07450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PING_RS07470	COG0019	diaminopimelate decarboxylase activity
PING_RS07475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PING_RS07475	COG3153	acetyltransferase
PING_RS07490	COG1139	Iron-sulfur cluster binding protein
PING_RS07500	COG1620	l-lactate permease
PING_RS07505	COG0583	DNA-binding transcription factor activity
PING_RS07540	COG3901	Regulator of nitric oxide reductase transcription
PING_RS07540	COG0348	domain, Protein
PING_RS07555	COG4895	conserved protein (DUF2196)
PING_RS07560	COG0730	response to heat
PING_RS07585	COG0488	(ABC) transporter
PING_RS07590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PING_RS07595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PING_RS07600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PING_RS07600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PING_RS07615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PING_RS07620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PING_RS07635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PING_RS07650	COG0277	FAD linked oxidase domain protein
PING_RS07650	COG0247	lactate metabolic process
PING_RS07655	COG2050	protein possibly involved in aromatic compounds catabolism
PING_RS07660	COG2996	Protein conserved in bacteria
PING_RS07665	COG1511	domain protein
PING_RS07665	COG3264	Mechanosensitive ion channel
PING_RS07670	COG2194	sulfuric ester hydrolase activity
PING_RS07685	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PING_RS07690	COG1074	ATP-dependent DNA helicase activity
PING_RS07695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PING_RS07700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PING_RS07705	COG0697	spore germination
PING_RS07710	COG2095	MarC family integral membrane protein
PING_RS07715	COG0544	peptidyl-prolyl cis-trans isomerase activity
PING_RS07720	COG0740	serine-type endopeptidase activity
PING_RS07725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PING_RS07730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PING_RS07740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PING_RS07745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PING_RS07755	COG1289	transmembrane transporter activity
PING_RS07760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PING_RS07770	COG0436	Aminotransferase
PING_RS07775	COG0583	DNA-binding transcription factor activity
PING_RS07780	COG0303	'Molybdopterin
PING_RS07785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PING_RS07795	COG3338	carbonate dehydratase activity
PING_RS07800	COG0259	pyridoxamine-phosphate oxidase activity
PING_RS07805	COG3101	peptidyl-lysine hydroxylation
PING_RS07830	COG1956	GAF domain-containing protein
PING_RS07835	COG0572	uridine kinase
PING_RS07855	COG1309	transcriptional regulator
PING_RS07900	COG2151	metal-sulfur cluster biosynthetic enzyme
PING_RS07905	COG0822	iron-sulfur transferase activity
PING_RS07910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PING_RS07915	COG0719	Fe-S assembly protein
PING_RS07920	COG0396	ATPase activity
PING_RS07925	COG0719	Fe-S assembly protein
PING_RS07935	COG3335	DDE superfamily endonuclease
PING_RS07955	COG0765	amino acid transport
PING_RS08005	COG2862	Uncharacterized protein family, UPF0114
PING_RS08025	COG0564	pseudouridine synthase activity
PING_RS08030	COG0513	Belongs to the DEAD box helicase family
PING_RS08035	COG0071	Belongs to the small heat shock protein (HSP20) family
PING_RS08040	COG0590	tRNA wobble adenosine to inosine editing
PING_RS08040	COG0037	tRNA processing
PING_RS08080	COG0739	heme binding
PING_RS08095	COG0415	Belongs to the DNA photolyase family
PING_RS08100	COG0415	Belongs to the DNA photolyase family
PING_RS08105	COG3046	protein related to deoxyribodipyrimidine photolyase
PING_RS08110	COG3293	Transposase
PING_RS08115	COG2095	MarC family integral membrane protein
PING_RS08155	COG3385	transposase activity
PING_RS08200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PING_RS08215	COG2079	MmgE PrpD family protein
PING_RS08225	COG2807	transmembrane transport
PING_RS08230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PING_RS08295	COG1203	CRISPR-associated helicase, Cas3
PING_RS08310	COG1857	crispr-associated protein
PING_RS08325	COG1518	maintenance of DNA repeat elements
PING_RS08330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PING_RS08365	COG3328	transposase activity
PING_RS08375	COG0582	viral genome integration into host DNA
PING_RS08380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PING_RS08385	COG2867	negative regulation of translational initiation
PING_RS08390	COG2914	Belongs to the UPF0125 (RnfH) family
PING_RS08395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PING_RS08400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PING_RS08405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PING_RS08410	COG2890	protein-(glutamine-N5) methyltransferase activity
PING_RS08420	COG2912	Transglutaminase-like superfamily
PING_RS08425	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PING_RS08430	COG2363	Small membrane protein
PING_RS08435	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PING_RS08440	COG3108	Peptidase M15
PING_RS08445	COG2989	Protein conserved in bacteria
PING_RS08450	COG1983	PspC domain protein
PING_RS08465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PING_RS08485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PING_RS08485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PING_RS08490	COG0489	protein tyrosine kinase activity
PING_RS08505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PING_RS08545	COG0004	ammonium transporteR
PING_RS08550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PING_RS08555	COG2233	PERMEase
PING_RS08585	COG1696	Membrane protein involved in D-alanine export
PING_RS08620	COG0330	HflC and HflK could
PING_RS08630	COG1979	alcohol dehydrogenase
PING_RS08635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PING_RS08635	COG0140	phosphoribosyl-ATP diphosphatase activity
PING_RS08640	COG0107	imidazoleglycerol-phosphate synthase activity
PING_RS08665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PING_RS08670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PING_RS08675	COG0131	Imidazoleglycerol-phosphate dehydratase
PING_RS08675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PING_RS08680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PING_RS08685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PING_RS08690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PING_RS08700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PING_RS08705	COG2186	Transcriptional regulator
PING_RS08710	COG1674	ftsk spoiiie
PING_RS08710	COG0531	amino acid
PING_RS08715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PING_RS08720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PING_RS08725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PING_RS08730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PING_RS08735	COG2211	Major facilitator Superfamily
PING_RS08740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PING_RS08745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PING_RS08750	COG0066	3-isopropylmalate dehydratase activity
PING_RS08805	COG1127	ABC transporter
PING_RS08810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PING_RS08815	COG2855	membrane
PING_RS08825	COG0604	alcohol dehydrogenase
PING_RS08825	COG3321	synthase
PING_RS08830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PING_RS08835	COG3321	synthase
PING_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
PING_RS08835	COG0604	alcohol dehydrogenase
PING_RS08840	COG2070	2-Nitropropane dioxygenase
PING_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PING_RS08855	COG0247	lactate metabolic process
PING_RS08860	COG1139	Iron-sulfur cluster binding protein
PING_RS08865	COG1556	Lactate utilization protein
PING_RS08875	COG0095	Lipoate-protein ligase
PING_RS08900	COG3706	GGDEF domain
PING_RS08915	COG1940	carbohydrate kinase activity
PING_RS08945	COG2226	methyltransferase
PING_RS08970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PING_RS09010	COG0697	spore germination
PING_RS09025	COG0456	acetyltransferase
PING_RS09030	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PING_RS09045	COG1335	isochorismatase
PING_RS09050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PING_RS09055	COG0110	maltose O-acetyltransferase activity
PING_RS09060	COG0598	Magnesium transport protein CorA
PING_RS09065	COG0531	amino acid
PING_RS09095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PING_RS09110	COG4628	conserved protein (DUF2132)
PING_RS09115	COG0281	malic enzyme
PING_RS09130	COG4191	Histidine kinase
PING_RS09135	COG2204	response regulator
PING_RS09180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PING_RS09245	COG3639	organic phosphonate transmembrane transporter activity
PING_RS09255	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PING_RS09260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PING_RS09265	COG0702	epimerase
PING_RS09295	COG1362	aminopeptidase activity
PING_RS09300	COG3920	Histidine kinase
PING_RS09300	COG2202	Pas domain
PING_RS09305	COG0657	acetylesterase activity
PING_RS09330	COG1294	oxidase, subunit
PING_RS09335	COG1271	oxidase subunit
PING_RS09350	COG1231	oxidoreductase activity
PING_RS09375	COG2814	Major facilitator Superfamily
PING_RS09405	COG0697	spore germination
PING_RS09415	COG0071	Belongs to the small heat shock protein (HSP20) family
PING_RS09420	COG0513	Belongs to the DEAD box helicase family
PING_RS09430	COG0673	inositol 2-dehydrogenase activity
PING_RS09435	COG2183	response to ionizing radiation
PING_RS09465	COG1408	metallophosphoesterase
PING_RS09480	COG1295	ribonuclease BN
PING_RS09490	COG3706	GGDEF domain
PING_RS09495	COG0596	Alpha beta hydrolase
PING_RS09525	COG1227	inorganic diphosphatase activity
PING_RS09540	COG2010	Cytochrome c
PING_RS09540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PING_RS09610	COG0798	PFAM Bile acid sodium symporter
PING_RS09660	COG1063	alcohol dehydrogenase
PING_RS09680	COG0417	DNA replication proofreading
PING_RS09690	COG3118	belongs to the thioredoxin family
PING_RS09695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PING_RS09700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PING_RS09705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PING_RS09715	COG4565	transcriptional regulatory protein
PING_RS09730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PING_RS09735	COG0372	Belongs to the citrate synthase family
PING_RS09740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PING_RS09745	COG1802	Transcriptional regulator
PING_RS09765	COG0561	phosphatase activity
PING_RS09780	COG4628	conserved protein (DUF2132)
PING_RS09795	COG2199	diguanylate cyclase activity
PING_RS09795	COG2203	Gaf domain
PING_RS09800	COG1278	Cold shock
PING_RS09810	COG0671	phosphoesterase, PA-phosphatase related
PING_RS09815	COG2816	NAD+ diphosphatase activity
PING_RS09820	COG2176	DNA-directed DNA polymerase activity
PING_RS09850	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PING_RS09885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PING_RS09890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PING_RS09900	COG2954	triphosphatase activity
PING_RS09910	COG3132	Protein of unknown function, DUF480
PING_RS09950	COG2911	Protein conserved in bacteria
PING_RS09955	COG0729	surface antigen
PING_RS09960	COG0501	Belongs to the peptidase M48B family
PING_RS09970	COG1126	abc transporter atp-binding protein
PING_RS09995	COG0156	8-amino-7-oxononanoate synthase activity
PING_RS10000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PING_RS10005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PING_RS10010	COG0017	Asparaginyl-tRNA synthetase
PING_RS10020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PING_RS10045	COG1247	-acetyltransferase
PING_RS10080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PING_RS10090	COG0789	Transcriptional regulator
PING_RS10120	COG3314	Sporulation integral membrane protein YlbJ
PING_RS10135	COG1278	Cold shock
PING_RS10140	COG0366	Alpha amylase catalytic
PING_RS10155	COG1175	transmembrane transport
PING_RS10160	COG0395	ABC-type sugar transport system, permease component
PING_RS10165	COG3842	ATPase activity
PING_RS10200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PING_RS10205	COG1286	toxin biosynthetic process
PING_RS10215	COG0285	dihydrofolate synthase activity
PING_RS10220	COG0101	tRNA pseudouridine synthase activity
PING_RS10230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PING_RS10235	COG0616	signal peptide processing
PING_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
PING_RS10245	COG1560	Kdo2-lipid A biosynthetic process
PING_RS10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PING_RS10255	COG1448	Aminotransferase
PING_RS10270	COG0583	DNA-binding transcription factor activity
PING_RS10280	COG1067	ATP-dependent peptidase activity
PING_RS10285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PING_RS10290	COG0616	signal peptide processing
PING_RS10300	COG1252	NADH dehydrogenase
PING_RS10305	COG3150	esterase
PING_RS10310	COG1472	Belongs to the glycosyl hydrolase 3 family
PING_RS10325	COG5433	transposase activity
PING_RS10335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PING_RS10340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PING_RS10345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PING_RS10350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PING_RS10350	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PING_RS10355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PING_RS10360	COG0596	Alpha beta hydrolase
PING_RS10365	COG0318	PFAM AMP-dependent synthetase and ligase
PING_RS10370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PING_RS10420	COG0395	ABC-type sugar transport system, permease component
PING_RS10425	COG1175	transmembrane transport
PING_RS10435	COG1263	PTS System
PING_RS10435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PING_RS10440	COG1609	Transcriptional regulator
PING_RS10450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PING_RS10455	COG1085	galactose-1-phosphate uridylyltransferase
PING_RS10460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PING_RS10465	COG2017	converts alpha-aldose to the beta-anomer
PING_RS10470	COG3250	beta-galactosidase activity
PING_RS10505	COG1473	amidohydrolase
PING_RS10510	COG2964	Protein conserved in bacteria
PING_RS10515	COG0251	oxidation-reduction process
PING_RS10520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PING_RS10535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PING_RS10540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PING_RS10545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PING_RS10565	COG0562	UDP-galactopyranose mutase
PING_RS10570	COG2244	polysaccharide biosynthetic process
PING_RS10575	COG5433	transposase activity
PING_RS10585	COG0783	Belongs to the Dps family
PING_RS10600	COG0583	DNA-binding transcription factor activity
PING_RS10605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PING_RS10610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PING_RS10615	COG0659	secondary active sulfate transmembrane transporter activity
PING_RS10640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PING_RS10655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS10660	COG1609	Transcriptional regulator
PING_RS10675	COG1451	nucleotide metabolic process
PING_RS10680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PING_RS10685	COG0217	transcriptional regulatory protein
PING_RS10705	COG3154	lipid carrier protein
PING_RS10710	COG1132	(ABC) transporter
PING_RS10715	COG1309	transcriptional regulator
PING_RS10720	COG1012	belongs to the aldehyde dehydrogenase family
PING_RS10740	COG4175	Glycine betaine
PING_RS10740	COG0517	IMP dehydrogenase activity
PING_RS10760	COG0431	NADPH-dependent FMN reductase
PING_RS10765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PING_RS10770	COG1115	amino acid carrier protein
PING_RS10775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PING_RS10785	COG0596	Alpha beta hydrolase
PING_RS10805	COG1349	DNA-binding transcription factor activity
PING_RS10810	COG0584	glycerophosphoryl diester phosphodiesterase
PING_RS10815	COG1653	transport
PING_RS10820	COG1175	transmembrane transport
PING_RS10825	COG0395	ABC-type sugar transport system, permease component
PING_RS10830	COG3842	ATPase activity
PING_RS10840	COG1794	racemase activity, acting on amino acids and derivatives
PING_RS10870	COG2200	EAL domain
PING_RS10870	COG2202	Pas domain
PING_RS10870	COG2199	diguanylate cyclase activity
PING_RS10875	COG0210	DNA helicase
PING_RS10895	COG1472	Belongs to the glycosyl hydrolase 3 family
PING_RS10940	COG3938	Belongs to the proline racemase family
PING_RS10955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PING_RS10975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PING_RS10990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PING_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
PING_RS11015	COG2020	methyltransferase activity
PING_RS11020	COG0477	Major facilitator Superfamily
PING_RS11060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PING_RS11100	COG5001	Diguanylate cyclase
PING_RS11100	COG4251	negative regulation of phosphorylation
PING_RS11100	COG3706	GGDEF domain
PING_RS11100	COG2203	Gaf domain
PING_RS11105	COG0129	dihydroxy-acid dehydratase activity
PING_RS11110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PING_RS11120	COG1716	ATPase activity
PING_RS11120	COG5001	Diguanylate cyclase
PING_RS11125	COG0697	spore germination
PING_RS11140	COG1278	Cold shock
PING_RS11150	COG0646	methionine synthase
PING_RS11150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PING_RS11155	COG0625	glutathione transferase activity
PING_RS11165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PING_RS11170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PING_RS11185	COG0314	molybdopterin synthase activity
PING_RS11190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PING_RS11195	COG0315	cyclic pyranopterin monophosphate synthase activity
PING_RS11200	COG0521	Mo-molybdopterin cofactor biosynthetic process
PING_RS11205	COG0746	molybdenum cofactor guanylyltransferase activity
PING_RS11220	COG0243	molybdopterin cofactor binding
PING_RS11225	COG3062	negative regulation of establishment of protein localization
PING_RS11230	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PING_RS11230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PING_RS11235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PING_RS11240	COG1199	ATP-dependent helicase activity
PING_RS11255	COG1254	Belongs to the acylphosphatase family
PING_RS11260	COG1280	lysine exporter protein (LysE YggA)
PING_RS11265	COG0215	cysteine-tRNA ligase activity
PING_RS11270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PING_RS11275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PING_RS11285	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PING_RS11290	COG0826	peptidase U32
PING_RS11295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PING_RS11310	COG4168	peptide transport system, permease
PING_RS11315	COG4171	peptide transport system, permease
PING_RS11320	COG4172	Belongs to the ABC transporter superfamily
PING_RS11325	COG4172	Belongs to the ABC transporter superfamily
PING_RS11330	COG5002	protein histidine kinase activity
PING_RS11330	COG5001	Diguanylate cyclase
PING_RS11335	COG0037	tRNA processing
PING_RS11340	COG0149	triose-phosphate isomerase activity
PING_RS11345	COG0670	Belongs to the BI1 family
PING_RS11350	COG4591	ABC-type transport system involved in lipoprotein release permease component
PING_RS11355	COG1136	(ABC) transporter
PING_RS11360	COG4591	ABC-type transport system involved in lipoprotein release permease component
PING_RS11365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PING_RS11375	COG0546	phosphoglycolate phosphatase activity
PING_RS11380	COG0564	pseudouridine synthase activity
PING_RS11385	COG1530	ribonuclease E activity
PING_RS11390	COG0492	ferredoxin-NADP+ reductase activity
PING_RS11400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PING_RS11405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PING_RS11410	COG1862	Preprotein translocase
PING_RS11415	COG0343	queuine tRNA-ribosyltransferase activity
PING_RS11420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PING_RS11425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PING_RS11430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PING_RS11440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PING_RS11445	COG3141	response to X-ray
PING_RS11455	COG2995	paraquat-inducible protein a
PING_RS11460	COG3008	intermembrane lipid transfer
PING_RS11465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PING_RS11465	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PING_RS11475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PING_RS11475	COG0301	tRNA thio-modification
PING_RS11485	COG0473	3-isopropylmalate dehydrogenase activity
PING_RS11490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PING_RS11495	COG5002	protein histidine kinase activity
PING_RS11500	COG0745	RESPONSE REGULATOR receiver
PING_RS11505	COG2974	May be involved in recombination
PING_RS11510	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PING_RS11530	COG1722	exodeoxyribonuclease VII activity
PING_RS11535	COG0142	geranyltranstransferase activity
PING_RS11540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PING_RS11550	COG1187	pseudouridine synthase activity
PING_RS11565	COG4628	conserved protein (DUF2132)
PING_RS11600	COG0045	succinate-CoA ligase (ADP-forming) activity
PING_RS11605	COG0508	dehydrogenase complex catalyzes the overall conversion of
PING_RS11610	COG0567	Dehydrogenase, E1 component
PING_RS11620	COG1053	succinate dehydrogenase
PING_RS11625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PING_RS11635	COG0372	Belongs to the citrate synthase family
PING_RS11640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PING_RS11650	COG3122	Protein conserved in bacteria
PING_RS11655	COG1666	GTP binding
PING_RS11660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PING_RS11675	COG0537	adenosine 5'-monophosphoramidase activity
PING_RS11690	COG3082	Protein of unknown function (DUF1414)
PING_RS11695	COG3083	sulfuric ester hydrolase activity
PING_RS11705	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PING_RS11710	COG1032	radical SAM domain protein
PING_RS11715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PING_RS11735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PING_RS11740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PING_RS11745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PING_RS11750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PING_RS11760	COG0488	(ABC) transporter
PING_RS11770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PING_RS11770	COG0116	Belongs to the methyltransferase superfamily
PING_RS11775	COG1653	transport
PING_RS11805	COG0019	diaminopimelate decarboxylase activity
PING_RS11810	COG3706	GGDEF domain
PING_RS11815	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PING_RS11820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PING_RS11825	COG0418	dihydroorotase activity
PING_RS11830	COG2824	Alkylphosphonate utilization operon protein PhnA
PING_RS11835	COG2813	Specifically methylates the guanine in position
PING_RS11840	COG0733	neurotransmitter:sodium symporter activity
PING_RS11850	COG0167	dihydroorotate dehydrogenase activity
PING_RS11860	COG1214	PFAM Peptidase M22, glycoprotease
PING_RS11865	COG1199	ATP-dependent helicase activity
PING_RS11880	COG1166	arginine decarboxylase activity
PING_RS11900	COG5001	Diguanylate cyclase
PING_RS11900	COG5002	protein histidine kinase activity
PING_RS11905	COG0596	Alpha beta hydrolase
PING_RS11920	COG0069	glutamate synthase activity
PING_RS11925	COG1846	Transcriptional regulator
PING_RS11930	COG1764	response to oxidative stress
PING_RS11985	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PING_RS12015	COG1132	(ABC) transporter
PING_RS12020	COG1132	(ABC) transporter
PING_RS12030	COG0471	metal ion transport
PING_RS12040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PING_RS12050	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PING_RS12060	COG0471	metal ion transport
PING_RS12070	COG0471	metal ion transport
PING_RS12075	COG0308	aminopeptidase N
PING_RS12080	COG1042	CoA-binding domain protein
PING_RS12080	COG0045	succinate-CoA ligase (ADP-forming) activity
PING_RS12080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PING_RS12085	COG0534	Mate efflux family protein
PING_RS12095	COG0297	glycogen (starch) synthase activity
PING_RS12120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PING_RS12155	COG0837	glucose binding
PING_RS12160	COG1737	Transcriptional regulator
PING_RS12165	COG0469	pyruvate kinase activity
PING_RS12170	COG3139	Protein of unknown function (DUF1315)
PING_RS12180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PING_RS12185	COG1640	4-alpha-glucanotransferase
PING_RS12190	COG0676	glucose-6-phosphate 1-epimerase activity
PING_RS12195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PING_RS12210	COG0714	Associated with various cellular activities
PING_RS12225	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PING_RS12230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PING_RS12235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PING_RS12240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PING_RS12245	COG1116	anion transmembrane transporter activity
PING_RS12250	COG0351	phosphomethylpyrimidine kinase
PING_RS12260	COG0366	Alpha amylase catalytic
PING_RS12265	COG0837	glucose binding
PING_RS12270	COG0366	Alpha amylase catalytic
PING_RS12310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PING_RS12330	COG0811	peptide transport
PING_RS12370	COG0405	Gamma-glutamyltransferase
PING_RS12395	COG0183	Belongs to the thiolase family
PING_RS12405	COG2130	NADP-dependent
PING_RS12420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PING_RS12425	COG0581	inorganic phosphate transmembrane transporter activity
PING_RS12430	COG0573	inorganic phosphate transmembrane transporter activity
PING_RS12445	COG2200	EAL domain
PING_RS12455	COG0248	Ppx GppA phosphatase
PING_RS12460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PING_RS12470	COG0583	DNA-binding transcription factor activity
PING_RS12485	COG0601	transmembrane transport
PING_RS12490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PING_RS12510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PING_RS12540	COG0765	amino acid transport
PING_RS12545	COG0765	amino acid transport
PING_RS12555	COG0697	spore germination
PING_RS12565	COG2925	Exonuclease
PING_RS12575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PING_RS12580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS12590	COG2190	(PTS) system
PING_RS12595	COG1393	Belongs to the ArsC family
PING_RS12600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PING_RS12605	COG1876	peptidase activity
PING_RS12615	COG0560	Phosphoserine phosphatase
PING_RS12635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PING_RS12650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PING_RS12660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PING_RS12680	COG0189	ligase activity
PING_RS12690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PING_RS12705	COG0582	viral genome integration into host DNA
PING_RS12710	COG0582	viral genome integration into host DNA
PING_RS12770	COG1397	ADP-ribosylglycohydrolase
PING_RS12855	COG0459	protein refolding
PING_RS12865	COG0582	viral genome integration into host DNA
PING_RS12910	COG2017	converts alpha-aldose to the beta-anomer
PING_RS12915	COG1609	Transcriptional regulator
PING_RS12925	COG1175	transmembrane transport
PING_RS12945	COG1979	alcohol dehydrogenase
PING_RS13015	COG3177	Filamentation induced by cAMP protein fic
PING_RS13020	COG1501	Belongs to the glycosyl hydrolase 31 family
PING_RS13025	COG1943	Transposase
PING_RS13045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PING_RS13050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PING_RS13060	COG2205	protein histidine kinase activity
PING_RS13075	COG2423	ornithine cyclodeaminase activity
PING_RS13090	COG1278	Cold shock
PING_RS13115	COG2814	Major facilitator Superfamily
PING_RS13170	COG1061	Type III restriction enzyme res subunit
PING_RS13210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PING_RS13215	COG1074	ATP-dependent DNA helicase activity
PING_RS13250	COG4974	Belongs to the 'phage' integrase family
PING_RS13315	COG2356	endonuclease I
PING_RS13355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PING_RS13370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PING_RS13375	COG0573	inorganic phosphate transmembrane transporter activity
PING_RS13380	COG0581	inorganic phosphate transmembrane transporter activity
PING_RS13385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PING_RS13390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PING_RS13400	COG2358	TRAP transporter, solute receptor (TAXI family
PING_RS13410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PING_RS13415	COG2095	MarC family integral membrane protein
PING_RS13430	COG1215	transferase activity, transferring glycosyl groups
PING_RS13435	COG3769	mannosylglycerate metabolic process
PING_RS13445	COG1250	3-hydroxyacyl-CoA dehydrogenase
PING_RS13445	COG1024	Enoyl-CoA hydratase
PING_RS13450	COG0183	Belongs to the thiolase family
PING_RS13455	COG1022	Amp-dependent synthetase and ligase
PING_RS13465	COG0400	carboxylic ester hydrolase activity
PING_RS13475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PING_RS13480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PING_RS13485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PING_RS13490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PING_RS13495	COG0202	RNA polymerase activity
PING_RS13500	COG0203	ribosomal protein L17
PING_RS13505	COG5265	(ABC) transporter
PING_RS13515	COG0477	Major facilitator Superfamily
PING_RS13530	COG1355	regulation of microtubule-based process
PING_RS13535	COG0484	heat shock protein binding
PING_RS13540	COG1388	LysM domain
PING_RS13540	COG1376	ErfK ybiS ycfS ynhG family protein
PING_RS13570	COG1785	Belongs to the alkaline phosphatase family
PING_RS13575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PING_RS13580	COG2137	regulation of response to DNA damage stimulus
PING_RS13585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PING_RS13605	COG3118	belongs to the thioredoxin family
PING_RS13620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PING_RS13630	COG2226	methyltransferase
PING_RS13690	COG2153	protein acetylation
PING_RS13700	COG0004	ammonium transporteR
PING_RS13710	COG0534	Mate efflux family protein
PING_RS13740	COG3751	2OG-Fe(II) oxygenase superfamily
PING_RS13755	COG1132	(ABC) transporter
PING_RS13775	COG0673	inositol 2-dehydrogenase activity
PING_RS13780	COG0667	Aldo Keto reductase
PING_RS13785	COG0667	Aldo Keto reductase
PING_RS13790	COG0583	DNA-binding transcription factor activity
PING_RS13795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PING_RS13800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PING_RS13815	COG0702	epimerase
PING_RS13825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PING_RS13845	COG3036	rescue of stalled ribosome
PING_RS13855	COG3588	fructose-bisphosphate aldolase
PING_RS13865	COG0494	nUDIX hydrolase
PING_RS13900	COG0443	Heat shock 70 kDa protein
PING_RS13925	COG0123	including yeast histone deacetylase and acetoin utilization protein
PING_RS13930	COG1278	Cold shock
PING_RS13940	COG3335	DDE superfamily endonuclease
PING_RS13950	COG3706	GGDEF domain
PING_RS13960	COG2766	serine protein kinase
PING_RS13965	COG2718	Belongs to the UPF0229 family
PING_RS13970	COG2719	SpoVR family
PING_RS13985	COG0534	Mate efflux family protein
PING_RS13990	COG0109	protoheme IX farnesyltransferase activity
PING_RS14015	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PING_RS14025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PING_RS14045	COG2926	Belongs to the UPF0265 family
PING_RS14050	COG2091	lysine biosynthetic process via aminoadipic acid
PING_RS14060	COG0513	Belongs to the DEAD box helicase family
PING_RS14065	COG1263	PTS System
PING_RS14065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PING_RS14080	COG0509	glycine decarboxylation via glycine cleavage system
PING_RS14085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PING_RS14085	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PING_RS14120	COG0579	oxidoreductase
PING_RS14150	COG2188	Transcriptional regulator
PING_RS14160	COG3842	ATPase activity
PING_RS14165	COG1840	ABC-type Fe3 transport system, periplasmic component
PING_RS14170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PING_RS14175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PING_RS14180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PING_RS14185	COG2084	Dehydrogenase
PING_RS14200	COG0363	glucosamine-6-phosphate deaminase activity
PING_RS14205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PING_RS14210	COG1648	precorrin-2 dehydrogenase activity
PING_RS14210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PING_RS14230	COG0583	DNA-binding transcription factor activity
PING_RS14235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PING_RS14245	COG0574	Belongs to the PEP-utilizing enzyme family
PING_RS14245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PING_RS14250	COG0668	transmembrane transport
PING_RS14285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PING_RS14290	COG4134	Bacterial extracellular solute-binding protein
PING_RS14295	COG4135	transport system, permease component
PING_RS14300	COG4136	ATPase activity
PING_RS14305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PING_RS14315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PING_RS14315	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PING_RS14325	COG1611	Belongs to the LOG family
PING_RS14330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PING_RS14345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PING_RS14350	COG0508	dehydrogenase complex catalyzes the overall conversion of
PING_RS14360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PING_RS14370	COG0006	proline dipeptidase activity
PING_RS14375	COG1609	Transcriptional regulator
PING_RS14385	COG1129	ABC transporter
PING_RS14390	COG1172	Belongs to the binding-protein-dependent transport system permease family
PING_RS14395	COG1172	Belongs to the binding-protein-dependent transport system permease family
PING_RS14400	COG1879	ABC-type sugar transport system periplasmic component
PING_RS14405	COG0459	protein refolding
PING_RS14415	COG2252	PERMEase
PING_RS14420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PING_RS14425	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PING_RS14445	COG0454	-acetyltransferase
PING_RS14455	COG0583	DNA-binding transcription factor activity
PING_RS14465	COG1072	(Pantothenic acid kinase))
PING_RS14470	COG1879	ABC-type sugar transport system periplasmic component
PING_RS14475	COG4191	Histidine kinase
PING_RS14475	COG0784	Response regulator, receiver
PING_RS14480	COG1879	ABC-type sugar transport system periplasmic component
PING_RS14485	COG1172	Belongs to the binding-protein-dependent transport system permease family
PING_RS14490	COG1129	ABC transporter
PING_RS14500	COG2062	phosphohistidine phosphatase, SixA
PING_RS14505	COG0714	Associated with various cellular activities
PING_RS14535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PING_RS14540	COG4597	amino acid ABC transporter
PING_RS14545	COG0765	amino acid transport
PING_RS14550	COG1126	abc transporter atp-binding protein
PING_RS14555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PING_RS14560	COG4597	amino acid ABC transporter
PING_RS14565	COG0765	amino acid transport
PING_RS14570	COG1126	abc transporter atp-binding protein
PING_RS14575	COG0189	ligase activity
PING_RS14575	COG4067	protein conserved in archaea
PING_RS14585	COG0189	ligase activity
PING_RS14590	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PING_RS14590	COG3264	Mechanosensitive ion channel
PING_RS14600	COG4160	amino acid transport
PING_RS14620	COG1584	GPR1 FUN34 yaaH family protein
PING_RS14625	COG0742	ribosomal rna small subunit methyltransferase
PING_RS14630	COG0439	Biotin carboxylase
PING_RS14645	COG0583	DNA-binding transcription factor activity
PING_RS14675	COG0457	Tetratricopeptide repeat
PING_RS14705	COG1278	Cold shock
PING_RS14710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PING_RS14725	COG0678	peroxiredoxin activity
PING_RS14730	COG4716	Myosin-crossreactive antigen
PING_RS14735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PING_RS14740	COG0254	rRNA binding
PING_RS14750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PING_RS14755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PING_RS14760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PING_RS14765	COG0813	purine-nucleoside phosphorylase activity
PING_RS14770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PING_RS14780	COG0295	cytidine deaminase activity
PING_RS14785	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PING_RS14790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PING_RS14795	COG2969	positive regulation of protein catabolic process
PING_RS14800	COG0625	glutathione transferase activity
PING_RS14805	COG2857	Cytochrome c1
PING_RS14810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PING_RS14815	COG0723	plastoquinol--plastocyanin reductase activity
PING_RS14825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PING_RS14830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PING_RS14835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PING_RS14850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PING_RS14865	COG2854	intermembrane phospholipid transfer
PING_RS14870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PING_RS14875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PING_RS14880	COG1127	ABC transporter
PING_RS14885	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PING_RS14895	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PING_RS14900	COG1137	ATPase activity
PING_RS14905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PING_RS14915	COG1660	Displays ATPase and GTPase activities
PING_RS14920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS14925	COG2239	Acts as a magnesium transporter
PING_RS14945	COG0501	Belongs to the peptidase M48B family
PING_RS14955	COG0625	glutathione transferase activity
PING_RS14990	COG0366	Alpha amylase catalytic
PING_RS14995	COG1609	Transcriptional regulator
PING_RS15005	COG1653	transport
PING_RS15010	COG1175	transmembrane transport
PING_RS15015	COG0395	ABC-type sugar transport system, permease component
PING_RS15020	COG3842	ATPase activity
PING_RS15075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PING_RS15080	COG0508	dehydrogenase complex catalyzes the overall conversion of
PING_RS15085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PING_RS15090	COG2186	Transcriptional regulator
PING_RS15095	COG1609	Transcriptional regulator
PING_RS15100	COG0800	Aldolase
PING_RS15110	COG3265	gluconokinase activity
PING_RS15130	COG3265	gluconokinase activity
PING_RS15135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PING_RS15140	COG0730	response to heat
PING_RS15170	COG1696	Membrane protein involved in D-alanine export
PING_RS15180	COG0582	viral genome integration into host DNA
PING_RS15195	COG0519	Catalyzes the synthesis of GMP from XMP
PING_RS15195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PING_RS15200	COG0517	IMP dehydrogenase activity
PING_RS15200	COG0516	GMP reductase activity
PING_RS15205	COG1570	exodeoxyribonuclease VII activity
PING_RS15210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PING_RS15215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PING_RS15225	COG1073	alpha beta
PING_RS15235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PING_RS15240	COG4181	ATPase activity
PING_RS15250	COG0037	tRNA processing
PING_RS15255	COG0587	DNA-directed DNA polymerase activity
PING_RS15260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PING_RS15265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PING_RS15270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PING_RS15275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PING_RS15280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PING_RS15290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PING_RS15295	COG0750	zinc metalloprotease
PING_RS15300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PING_RS15305	COG0575	Belongs to the CDS family
PING_RS15310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PING_RS15315	COG0233	cytoplasmic translational termination
PING_RS15320	COG0528	UMP kinase activity
PING_RS15325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PING_RS15330	COG0052	Belongs to the universal ribosomal protein uS2 family
PING_RS15365	COG2186	Transcriptional regulator
PING_RS15375	COG0745	RESPONSE REGULATOR receiver
PING_RS15380	COG0784	Response regulator, receiver
PING_RS15380	COG2198	Histidine kinase
PING_RS15380	COG2205	protein histidine kinase activity
PING_RS15405	COG3842	ATPase activity
PING_RS15410	COG0829	nickel cation binding
PING_RS15415	COG0831	urea catabolic process
PING_RS15420	COG0832	Belongs to the urease beta subunit family
PING_RS15425	COG0804	urea catabolic process
PING_RS15430	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PING_RS15435	COG0830	nickel cation binding
PING_RS15440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PING_RS15470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PING_RS15475	COG0024	Methionine aminopeptidase
PING_RS15480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PING_RS15485	COG3842	ATPase activity
PING_RS15495	COG1840	ABC-type Fe3 transport system, periplasmic component
PING_RS15505	COG0284	orotidine-5'-phosphate decarboxylase activity
PING_RS15510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PING_RS15515	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PING_RS15520	COG0776	regulation of translation
PING_RS15525	COG0539	negative regulation of cytoplasmic translation
PING_RS15530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PING_RS15550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PING_RS15555	COG1138	Cytochrome C-type biogenesis protein
PING_RS15560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PING_RS15565	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PING_RS15570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PING_RS15575	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PING_RS15580	COG4133	protoheme IX ABC transporter activity
PING_RS15585	COG0004	ammonium transporteR
PING_RS15590	COG0347	Belongs to the P(II) protein family
PING_RS15595	COG1686	Belongs to the peptidase S11 family
PING_RS15600	COG2921	Belongs to the UPF0250 family
PING_RS15605	COG0321	lipoyl(octanoyl) transferase activity
PING_RS15610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PING_RS15615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PING_RS15620	COG2813	Specifically methylates the guanine in position
PING_RS15625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PING_RS15630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PING_RS15635	COG0297	glycogen (starch) synthase activity
PING_RS15640	COG0513	Belongs to the DEAD box helicase family
PING_RS15645	COG3022	response to hydroperoxide
PING_RS15665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PING_RS15670	COG0762	integral membrane protein
PING_RS15675	COG1872	DUF167
PING_RS15685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PING_RS15690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PING_RS15795	COG1872	DUF167
PING_RS15825	COG3447	MASE1 domain protein
PING_RS15825	COG5001	Diguanylate cyclase
PING_RS15825	COG5002	protein histidine kinase activity
PING_RS15855	COG3706	GGDEF domain
PING_RS15875	COG1902	pentaerythritol trinitrate reductase activity
PING_RS15885	COG5001	Diguanylate cyclase
PING_RS15890	COG2814	Major facilitator Superfamily
PING_RS15905	COG2200	EAL domain
PING_RS15920	COG1278	Cold shock
PING_RS15930	COG1278	Cold shock
PING_RS16030	COG2081	HI0933 family
PING_RS16035	COG0545	Peptidyl-prolyl cis-trans isomerase
PING_RS16040	COG2900	Belongs to the SlyX family
PING_RS16055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PING_RS16060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PING_RS16110	COG0633	Ferredoxin
PING_RS16125	COG0697	spore germination
PING_RS16145	COG3101	peptidyl-lysine hydroxylation
PING_RS16175	COG1785	Belongs to the alkaline phosphatase family
PING_RS16195	COG0307	riboflavin synthase, alpha
PING_RS16225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PING_RS16235	COG4676	Protein conserved in bacteria
PING_RS16245	COG0300	oxidoreductase activity
PING_RS16255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PING_RS16260	COG4172	Belongs to the ABC transporter superfamily
PING_RS16265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PING_RS16275	COG0747	negative chemotaxis
PING_RS16310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PING_RS16325	COG0395	ABC-type sugar transport system, permease component
PING_RS16335	COG3842	ATPase activity
PING_RS16340	COG3842	ATPase activity
PING_RS16345	COG3284	Transcriptional regulator
PING_RS16350	COG1349	DNA-binding transcription factor activity
PING_RS16355	COG0584	glycerophosphoryl diester phosphodiesterase
PING_RS16365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PING_RS16370	COG0735	belongs to the Fur family
PING_RS16400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PING_RS16400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PING_RS16415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PING_RS16430	COG0513	Belongs to the DEAD box helicase family
PING_RS16435	COG0248	Ppx GppA phosphatase
PING_RS16445	COG3335	DDE superfamily endonuclease
PING_RS16475	COG3123	guanosine phosphorylase activity
PING_RS16480	COG0488	(ABC) transporter
PING_RS16490	COG1047	Peptidyl-prolyl cis-trans
PING_RS16500	COG1040	competence protein
PING_RS16505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PING_RS16505	COG0316	Belongs to the HesB IscA family
PING_RS16510	COG0513	Belongs to the DEAD box helicase family
PING_RS16515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PING_RS16520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PING_RS16530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PING_RS16535	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PING_RS16545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PING_RS16550	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PING_RS16575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PING_RS16590	COG0151	Belongs to the GarS family
PING_RS16595	COG0138	bifunctional purine biosynthesis protein purh
PING_RS16605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PING_RS16620	COG0739	heme binding
PING_RS16630	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PING_RS16640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PING_RS16645	COG0456	acetyltransferase
PING_RS16650	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
PING_RS16655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PING_RS16670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PING_RS16675	COG0330	HflC and HflK could
PING_RS16680	COG0330	HflC and HflK could
PING_RS16685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PING_RS16690	COG1923	regulation of RNA biosynthetic process
PING_RS16695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PING_RS16700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PING_RS16705	COG0860	N-Acetylmuramoyl-L-alanine amidase
PING_RS16710	COG0802	atpase or kinase
PING_RS16715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PING_RS16715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PING_RS16720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PING_RS16735	COG0583	DNA-binding transcription factor activity
PING_RS16785	COG1760	l-serine dehydratase
PING_RS16800	COG0513	Belongs to the DEAD box helicase family
PING_RS16805	COG0488	(ABC) transporter
PING_RS16815	COG0667	Aldo Keto reductase
PING_RS16820	COG0542	response to heat
PING_RS16825	COG1496	oxidoreductase activity
PING_RS16830	COG0564	pseudouridine synthase activity
PING_RS16835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PING_RS16845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PING_RS16850	COG1047	Peptidyl-prolyl cis-trans
PING_RS16855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PING_RS16860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PING_RS16865	COG0196	riboflavin kinase activity
PING_RS16870	COG0728	peptidoglycan biosynthetic process
PING_RS16875	COG0268	Binds directly to 16S ribosomal RNA
PING_RS16895	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PING_RS16900	COG1053	succinate dehydrogenase
PING_RS16905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PING_RS16910	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PING_RS16920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PING_RS16955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PING_RS16965	COG1720	tRNA m6t6A37 methyltransferase activity
PING_RS16975	COG0442	prolyl-tRNA aminoacylation
PING_RS16980	COG2267	carboxylic ester hydrolase activity
PING_RS16985	COG0561	phosphatase activity
PING_RS16995	COG2027	D-alanyl-D-alanine carboxypeptidase
PING_RS17000	COG0540	Belongs to the ATCase OTCase family
PING_RS17005	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PING_RS17010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PING_RS17015	COG3074	FtsZ-dependent cytokinesis
PING_RS17035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PING_RS17040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PING_RS17045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PING_RS17055	COG0716	FMN binding
PING_RS17060	COG2116	formate transmembrane transporter activity
PING_RS17065	COG1882	Formate acetyltransferase
PING_RS17070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PING_RS17075	COG2226	methyltransferase
PING_RS17080	COG3092	negative regulation of chromosome organization
PING_RS17085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PING_RS17090	COG0280	phosphate acetyltransferase
PING_RS17090	COG0857	belongs to the CobB CobQ family
PING_RS17095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PING_RS17095	COG0116	Belongs to the methyltransferase superfamily
PING_RS17100	COG0628	permease
PING_RS17105	COG1454	alcohol dehydrogenase
PING_RS17105	COG1012	belongs to the aldehyde dehydrogenase family
PING_RS17120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PING_RS17120	COG0047	phosphoribosylformylglycinamidine synthase activity
PING_RS17125	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PING_RS17140	COG0242	peptide deformylase activity
PING_RS17145	COG0590	tRNA wobble adenosine to inosine editing
PING_RS17155	COG0105	UTP biosynthetic process
PING_RS17170	COG5002	protein histidine kinase activity
PING_RS17170	COG0784	Response regulator, receiver
PING_RS17170	COG2205	protein histidine kinase activity
PING_RS17195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PING_RS17215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PING_RS17220	COG1162	GTPase activity
PING_RS17225	COG0688	phosphatidylethanolamine metabolic process
PING_RS17230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PING_RS17235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PING_RS17240	COG4206	TonB-dependent receptor
PING_RS17245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PING_RS17250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PING_RS17255	COG1120	ATPase activity
PING_RS17260	COG0811	peptide transport
PING_RS17265	COG0848	biopolymer transport protein
PING_RS17280	COG2130	NADP-dependent
PING_RS17285	COG1979	alcohol dehydrogenase
PING_RS17295	COG0583	DNA-binding transcription factor activity
PING_RS17305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PING_RS17310	COG0187	DNA topoisomerase II activity
PING_RS17315	COG2084	Dehydrogenase
PING_RS17325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PING_RS17330	COG0494	nUDIX hydrolase
PING_RS17335	COG1538	Outer membrane efflux protein
PING_RS17340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PING_RS17340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PING_RS17345	COG4191	Histidine kinase
PING_RS17345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PING_RS17350	COG2832	Protein of unknown function (DUF454)
PING_RS17355	COG0335	large ribosomal subunit rRNA binding
PING_RS17360	COG0336	Belongs to the RNA methyltransferase TrmD family
PING_RS17365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PING_RS17370	COG0228	four-way junction DNA binding
PING_RS17375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PING_RS17380	COG4137	Cytochrome C assembly protein
PING_RS17385	COG4536	flavin adenine dinucleotide binding
PING_RS17390	COG1854	S-ribosylhomocysteine lyase activity
PING_RS17400	COG2918	glutathione biosynthetic process
PING_RS17405	COG1238	metal cluster binding
PING_RS17410	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PING_RS17445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PING_RS17450	COG0527	aspartate kinase activity
PING_RS17455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PING_RS17460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PING_RS17465	COG1546	Belongs to the CinA family
PING_RS17470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PING_RS17480	COG0583	DNA-binding transcription factor activity
PING_RS17485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PING_RS17500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PING_RS17505	COG2814	Major facilitator Superfamily
PING_RS17515	COG2199	diguanylate cyclase activity
PING_RS17520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PING_RS17525	COG0252	asparaginase activity
PING_RS17535	COG0514	ATP-dependent DNA helicase (RecQ)
PING_RS17540	COG3148	PFAM DTW domain containing protein
PING_RS17545	COG0561	phosphatase activity
PING_RS17550	COG0561	phosphatase activity
PING_RS17555	COG0561	phosphatase activity
PING_RS17570	COG1763	Mo-molybdopterin cofactor biosynthetic process
PING_RS17580	COG4989	oxidoreductase activity
PING_RS17590	COG1054	Belongs to the UPF0176 family
PING_RS17595	COG1785	Belongs to the alkaline phosphatase family
PING_RS17600	COG1785	Belongs to the alkaline phosphatase family
PING_RS17660	COG0557	exoribonuclease II activity
PING_RS17665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PING_RS17670	COG0360	Binds together with S18 to 16S ribosomal RNA
PING_RS17675	COG2965	DNA replication, synthesis of RNA primer
PING_RS17680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PING_RS17685	COG0359	binds to the 23S rRNA
PING_RS17705	COG4176	ABC-type proline glycine betaine transport system permease component
PING_RS17710	COG0517	IMP dehydrogenase activity
PING_RS17710	COG4175	Glycine betaine
PING_RS17720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PING_RS17725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PING_RS17730	COG0028	Belongs to the TPP enzyme family
PING_RS17735	COG0440	acetolactate synthase activity
PING_RS17755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PING_RS17760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PING_RS17765	COG0175	sulfate reduction
PING_RS17770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PING_RS17775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PING_RS17780	COG0049	tRNA binding
PING_RS17785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PING_RS17800	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PING_RS17805	COG0251	oxidation-reduction process
PING_RS17810	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PING_RS17815	COG0085	RNA polymerase activity
PING_RS17820	COG0222	ribosome binding
PING_RS17825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PING_RS17830	COG0081	regulation of translation
PING_RS17835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PING_RS17845	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PING_RS17850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PING_RS17855	COG4988	ABC transporter
PING_RS17885	COG1134	teichoic acid transport
PING_RS17925	COG3161	chorismate lyase activity
PING_RS17930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PING_RS17945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PING_RS17945	COG0678	peroxiredoxin activity
PING_RS17950	COG0210	DNA helicase
PING_RS17960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PING_RS17965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PING_RS17970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PING_RS17975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PING_RS17980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PING_RS17985	COG1025	Belongs to the peptidase M16 family
PING_RS17990	COG1490	D-aminoacyl-tRNA deacylase activity
PING_RS17995	COG1295	ribonuclease BN
PING_RS18000	COG1217	gtp-binding protein TYPA
PING_RS18005	COG0174	glutamine synthetase
PING_RS18020	COG3852	Histidine kinase
PING_RS18035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PING_RS18045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PING_RS18065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PING_RS18075	COG0203	ribosomal protein L17
PING_RS18080	COG0202	RNA polymerase activity
PING_RS18085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PING_RS18090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PING_RS18095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PING_RS18100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PING_RS18105	COG0201	protein transport
PING_RS18110	COG0200	Binds to the 23S rRNA
PING_RS18115	COG1841	ribosomal large subunit assembly
PING_RS18120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PING_RS18125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PING_RS18130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PING_RS18135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PING_RS18140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PING_RS18145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PING_RS18150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PING_RS18155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PING_RS18160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PING_RS18165	COG0255	Belongs to the universal ribosomal protein uL29 family
PING_RS18170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PING_RS18175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PING_RS18180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PING_RS18185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PING_RS18190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PING_RS18195	COG0089	rRNA binding
PING_RS18200	COG0088	Forms part of the polypeptide exit tunnel
PING_RS18205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PING_RS18210	COG0051	transcription antitermination factor activity, RNA binding
PING_RS18215	COG1444	tRNA N-acetyltransferase activity
PING_RS18220	COG1187	pseudouridine synthase activity
PING_RS18225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PING_RS18230	COG0583	DNA-binding transcription factor activity
PING_RS18245	COG0346	lactoylglutathione lyase activity
PING_RS18265	COG1464	Belongs to the NlpA lipoprotein family
PING_RS18270	COG2011	ABC-type metal ion transport system permease component
PING_RS18275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PING_RS18285	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PING_RS18305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PING_RS18330	COG1984	allophanate hydrolase subunit 2
PING_RS18335	COG1609	Transcriptional regulator
PING_RS18340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS18340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PING_RS18345	COG1105	Belongs to the carbohydrate kinase PfkB family
PING_RS18350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PING_RS18350	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PING_RS18350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PING_RS18355	COG0698	ribose 5-phosphate isomerase
PING_RS18360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PING_RS18365	COG3040	lipid binding
PING_RS18400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PING_RS18410	COG1677	Flagellar hook-basal body complex protein FliE
PING_RS18425	COG1256	bacterial-type flagellum assembly
PING_RS18425	COG4786	Flagellar basal body rod
PING_RS18435	COG1706	bacterial-type flagellum-dependent cell motility
PING_RS18440	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PING_RS18445	COG4786	Flagellar basal body rod
PING_RS18450	COG4786	Flagellar basal body rod
PING_RS18455	COG1749	Flagellar hook protein flgE
PING_RS18460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PING_RS18465	COG1558	bacterial-type flagellum-dependent cell motility
PING_RS18470	COG1815	bacterial-type flagellum-dependent cell motility
PING_RS18475	COG1360	Flagellar Motor Protein
PING_RS18480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PING_RS18515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PING_RS18520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PING_RS18525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PING_RS18540	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PING_RS18550	COG1987	bacterial-type flagellum assembly
PING_RS18560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PING_RS18580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PING_RS18585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PING_RS18590	COG0508	dehydrogenase complex catalyzes the overall conversion of
PING_RS18590	COG0022	dehydrogenase e1 component
PING_RS18595	COG0508	dehydrogenase complex catalyzes the overall conversion of
PING_RS18605	COG0686	Belongs to the AlaDH PNT family
PING_RS18615	COG4232	protein-disulfide reductase activity
PING_RS18620	COG0594	ribonuclease P activity
PING_RS18625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PING_RS18630	COG0706	membrane insertase activity
PING_RS18635	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PING_RS18645	COG1090	epimerase
PING_RS18655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PING_RS18660	COG1494	fructose-1,6-bisphosphatase
PING_RS18670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PING_RS18675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PING_RS18685	COG1072	(Pantothenic acid kinase))
PING_RS18695	COG1758	RNA polymerase activity
PING_RS18725	COG0640	Transcriptional regulator
PING_RS18735	COG2391	methyltransferase activity
PING_RS18750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PING_RS18755	COG0640	Transcriptional regulator
PING_RS18770	COG2959	enzyme of heme biosynthesis
PING_RS18780	COG0181	hydroxymethylbilane synthase activity
PING_RS18785	COG3530	Putative quorum-sensing-regulated virulence factor
PING_RS18790	COG2873	o-acetylhomoserine
PING_RS18810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PING_RS18830	COG0523	cobalamin synthesis protein
PING_RS18835	COG1561	YicC-like family, N-terminal region
PING_RS18840	COG3171	Protein conserved in bacteria
PING_RS18845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PING_RS18860	COG3052	prosthetic group binding
PING_RS18920	COG1802	Transcriptional regulator
PING_RS18925	COG2801	Transposase and inactivated derivatives
PING_RS18945	COG3473	Maleate cis-trans isomerase
PING_RS18970	COG0730	response to heat
PING_RS18985	COG3335	DDE superfamily endonuclease
PING_RS19000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PING_RS19005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PING_RS19010	COG3454	Phosphonate metabolism
PING_RS19015	COG4778	phosphonate C-P lyase system protein PhnL
PING_RS19020	COG4107	phosphonate C-P lyase system protein PhnK
PING_RS19025	COG3627	carbon phosphorus lyase activity
PING_RS19050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PING_RS19060	COG2188	Transcriptional regulator
PING_RS19065	COG2962	Rard protein
PING_RS19075	COG0625	glutathione transferase activity
PING_RS19095	COG1278	Cold shock
PING_RS19110	COG1136	(ABC) transporter
PING_RS19110	COG0577	efflux transmembrane transporter activity
PING_RS19115	COG1136	(ABC) transporter
PING_RS19115	COG0577	efflux transmembrane transporter activity
PING_RS19120	COG1136	(ABC) transporter
PING_RS19120	COG0577	efflux transmembrane transporter activity
PING_RS19140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PING_RS19145	COG0592	DNA-directed DNA polymerase activity
PING_RS19150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PING_RS19155	COG0187	DNA topoisomerase II activity
PING_RS19165	COG5002	protein histidine kinase activity
PING_RS19165	COG0784	Response regulator, receiver
PING_RS19170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PING_RS19190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PING_RS19195	COG3977	Valine--pyruvate aminotransferase
PING_RS19200	COG0751	glycine-tRNA ligase activity
PING_RS19205	COG0752	glycyl-tRNA synthetase alpha subunit
PING_RS19220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PING_RS19225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PING_RS19230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PING_RS19235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PING_RS19240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PING_RS19250	COG0356	it plays a direct role in the translocation of protons across the membrane
PING_RS19255	COG3312	ion transport
PING_RS19260	COG1475	DNA binding
PING_RS19265	COG1192	Involved in chromosome partitioning
PING_RS19270	COG0357	Ribosomal RNA small subunit methyltransferase G
PING_RS19275	COG0445	tRNA wobble uridine modification
PING_RS19280	COG0716	FMN binding
PING_RS19350	COG5433	transposase activity
PING_RS19385	COG0470	DNA polymerase III
PING_RS19390	COG5001	Diguanylate cyclase
PING_RS19400	COG1024	Enoyl-CoA hydratase
PING_RS19400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PING_RS19505	COG0784	Response regulator, receiver
PING_RS19505	COG4191	Histidine kinase
PING_RS19510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PING_RS19515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PING_RS19535	COG2205	protein histidine kinase activity
PING_RS19535	COG0784	Response regulator, receiver
PING_RS19570	COG3646	Phage regulatory protein