locus-tag	class	description
PCNPT3_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PCNPT3_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCNPT3_RS00020	COG0187	DNA topoisomerase II activity
PCNPT3_RS00030	COG3977	Valine--pyruvate aminotransferase
PCNPT3_RS00035	COG0751	glycine-tRNA ligase activity
PCNPT3_RS00040	COG0752	glycyl-tRNA synthetase alpha subunit
PCNPT3_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
PCNPT3_RS00070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCNPT3_RS00105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PCNPT3_RS00120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCNPT3_RS00125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCNPT3_RS00155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PCNPT3_RS00160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PCNPT3_RS00165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PCNPT3_RS00170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PCNPT3_RS00175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCNPT3_RS00180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PCNPT3_RS00190	COG0356	it plays a direct role in the translocation of protons across the membrane
PCNPT3_RS00205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PCNPT3_RS00210	COG1475	DNA binding
PCNPT3_RS00215	COG1192	Involved in chromosome partitioning
PCNPT3_RS00220	COG0357	Ribosomal RNA small subunit methyltransferase G
PCNPT3_RS00225	COG0445	tRNA wobble uridine modification
PCNPT3_RS00230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PCNPT3_RS00275	COG1473	amidohydrolase
PCNPT3_RS00280	COG0573	inorganic phosphate transmembrane transporter activity
PCNPT3_RS00285	COG0573	inorganic phosphate transmembrane transporter activity
PCNPT3_RS00290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCNPT3_RS00345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PCNPT3_RS00350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PCNPT3_RS00360	COG0018	arginyl-trna synthetase
PCNPT3_RS00365	COG0210	DNA helicase
PCNPT3_RS00370	COG1011	Hydrolase
PCNPT3_RS00375	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PCNPT3_RS00380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PCNPT3_RS00385	COG0019	diaminopimelate decarboxylase activity
PCNPT3_RS00395	COG1965	Belongs to the frataxin family
PCNPT3_RS00405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PCNPT3_RS00410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PCNPT3_RS00420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PCNPT3_RS00425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PCNPT3_RS00435	COG0756	dUTP diphosphatase activity
PCNPT3_RS00440	COG1309	transcriptional regulator
PCNPT3_RS00445	COG0668	transmembrane transport
PCNPT3_RS00455	COG3072	Adenylate cyclase
PCNPT3_RS00465	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PCNPT3_RS00475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PCNPT3_RS00480	COG1595	DNA-templated transcription, initiation
PCNPT3_RS00565	COG3842	ATPase activity
PCNPT3_RS00570	COG0395	ABC-type sugar transport system, permease component
PCNPT3_RS00580	COG1653	transport
PCNPT3_RS00585	COG0584	glycerophosphoryl diester phosphodiesterase
PCNPT3_RS00605	COG2271	Major facilitator Superfamily
PCNPT3_RS00610	COG0469	pyruvate kinase activity
PCNPT3_RS00615	COG1288	antiporter activity
PCNPT3_RS00620	COG1328	CTP reductase activity
PCNPT3_RS00625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCNPT3_RS00655	COG1414	Transcriptional regulator
PCNPT3_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
PCNPT3_RS00670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCNPT3_RS00675	COG0800	Aldolase
PCNPT3_RS00680	COG2731	YhcH YjgK YiaL family protein
PCNPT3_RS00685	COG0181	hydroxymethylbilane synthase activity
PCNPT3_RS00695	COG2959	enzyme of heme biosynthesis
PCNPT3_RS00700	COG3071	HemY protein
PCNPT3_RS00715	COG4232	protein-disulfide reductase activity
PCNPT3_RS00720	COG3381	protein complex oligomerization
PCNPT3_RS00725	COG0243	molybdopterin cofactor binding
PCNPT3_RS00730	COG3005	denitrification pathway
PCNPT3_RS00735	COG4459	periplasmic nitrate reductase
PCNPT3_RS00740	COG3530	Putative quorum-sensing-regulated virulence factor
PCNPT3_RS00745	COG0009	L-threonylcarbamoyladenylate synthase
PCNPT3_RS00750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCNPT3_RS00755	COG0551	DNA topoisomerase type I activity
PCNPT3_RS00760	COG2922	Belongs to the Smg family
PCNPT3_RS00765	COG0758	DNA mediated transformation
PCNPT3_RS00775	COG0242	peptide deformylase activity
PCNPT3_RS00780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PCNPT3_RS00785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCNPT3_RS00785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCNPT3_RS00790	COG0569	domain protein
PCNPT3_RS00795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCNPT3_RS00810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PCNPT3_RS00815	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PCNPT3_RS00825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCNPT3_RS00830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PCNPT3_RS00840	COG2116	formate transmembrane transporter activity
PCNPT3_RS00850	COG1758	RNA polymerase activity
PCNPT3_RS00855	COG0194	GDP metabolic process
PCNPT3_RS00870	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PCNPT3_RS00875	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PCNPT3_RS00880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PCNPT3_RS00905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCNPT3_RS00955	COG4964	Belongs to the GSP D family
PCNPT3_RS00980	COG3031	protein transport across the cell outer membrane
PCNPT3_RS00985	COG1450	Type ii and iii secretion system protein
PCNPT3_RS00990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCNPT3_RS00995	COG1459	type II secretion system
PCNPT3_RS01015	COG4795	General secretion pathway protein
PCNPT3_RS01020	COG3156	type II secretion system protein K
PCNPT3_RS01045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PCNPT3_RS01055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCNPT3_RS01065	COG2207	Transcriptional regulator
PCNPT3_RS01075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PCNPT3_RS01095	COG4932	domain protein
PCNPT3_RS01095	COG5492	domain, Protein
PCNPT3_RS01105	COG1187	pseudouridine synthase activity
PCNPT3_RS01110	COG1444	tRNA N-acetyltransferase activity
PCNPT3_RS01115	COG0051	transcription antitermination factor activity, RNA binding
PCNPT3_RS01120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PCNPT3_RS01125	COG0088	Forms part of the polypeptide exit tunnel
PCNPT3_RS01130	COG0089	rRNA binding
PCNPT3_RS01135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PCNPT3_RS01140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PCNPT3_RS01145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PCNPT3_RS01150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PCNPT3_RS01155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PCNPT3_RS01160	COG0255	Belongs to the universal ribosomal protein uL29 family
PCNPT3_RS01165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PCNPT3_RS01170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PCNPT3_RS01175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PCNPT3_RS01180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PCNPT3_RS01185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PCNPT3_RS01190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PCNPT3_RS01195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PCNPT3_RS01200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PCNPT3_RS01205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PCNPT3_RS01210	COG1841	ribosomal large subunit assembly
PCNPT3_RS01215	COG0200	Binds to the 23S rRNA
PCNPT3_RS01220	COG0201	protein transport
PCNPT3_RS01225	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PCNPT3_RS01230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PCNPT3_RS01235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PCNPT3_RS01240	COG0202	RNA polymerase activity
PCNPT3_RS01245	COG0203	ribosomal protein L17
PCNPT3_RS01255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PCNPT3_RS01265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCNPT3_RS01275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCNPT3_RS01290	COG1105	Belongs to the carbohydrate kinase PfkB family
PCNPT3_RS01295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCNPT3_RS01295	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PCNPT3_RS01300	COG1151	hydroxylamine reductase activity
PCNPT3_RS01305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCNPT3_RS01310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCNPT3_RS01315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PCNPT3_RS01325	COG3852	Histidine kinase
PCNPT3_RS01335	COG0174	glutamine synthetase
PCNPT3_RS01340	COG1217	gtp-binding protein TYPA
PCNPT3_RS01355	COG1295	ribonuclease BN
PCNPT3_RS01360	COG1490	D-aminoacyl-tRNA deacylase activity
PCNPT3_RS01365	COG1025	Belongs to the peptidase M16 family
PCNPT3_RS01370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PCNPT3_RS01375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PCNPT3_RS01390	COG2204	response regulator
PCNPT3_RS01415	COG4191	Histidine kinase
PCNPT3_RS01420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PCNPT3_RS01425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PCNPT3_RS01455	COG0438	transferase activity, transferring glycosyl groups
PCNPT3_RS01460	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PCNPT3_RS01505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCNPT3_RS01510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCNPT3_RS01520	COG0210	DNA helicase
PCNPT3_RS01525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCNPT3_RS01525	COG0678	peroxiredoxin activity
PCNPT3_RS01530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCNPT3_RS01535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PCNPT3_RS01540	COG3161	chorismate lyase activity
PCNPT3_RS01550	COG0228	four-way junction DNA binding
PCNPT3_RS01555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PCNPT3_RS01560	COG0336	Belongs to the RNA methyltransferase TrmD family
PCNPT3_RS01565	COG0335	large ribosomal subunit rRNA binding
PCNPT3_RS01570	COG2832	Protein of unknown function (DUF454)
PCNPT3_RS01575	COG4191	Histidine kinase
PCNPT3_RS01575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCNPT3_RS01580	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PCNPT3_RS01580	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PCNPT3_RS01585	COG1538	Outer membrane efflux protein
PCNPT3_RS01590	COG0494	nUDIX hydrolase
PCNPT3_RS01595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PCNPT3_RS01600	COG3150	esterase
PCNPT3_RS01605	COG0187	DNA topoisomerase II activity
PCNPT3_RS01610	COG0105	UTP biosynthetic process
PCNPT3_RS01620	COG0590	tRNA wobble adenosine to inosine editing
PCNPT3_RS01625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PCNPT3_RS01635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCNPT3_RS01635	COG0047	phosphoribosylformylglycinamidine synthase activity
PCNPT3_RS01640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCNPT3_RS01645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCNPT3_RS01655	COG1872	DUF167
PCNPT3_RS01660	COG0762	integral membrane protein
PCNPT3_RS01665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCNPT3_RS01670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PCNPT3_RS01680	COG3022	response to hydroperoxide
PCNPT3_RS01685	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS01705	COG0811	peptide transport
PCNPT3_RS01710	COG1120	ATPase activity
PCNPT3_RS01720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PCNPT3_RS01725	COG4206	TonB-dependent receptor
PCNPT3_RS01730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PCNPT3_RS01735	COG0688	phosphatidylethanolamine metabolic process
PCNPT3_RS01740	COG1162	GTPase activity
PCNPT3_RS01745	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PCNPT3_RS01760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PCNPT3_RS01765	COG0425	Belongs to the sulfur carrier protein TusA family
PCNPT3_RS01770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PCNPT3_RS01780	COG0137	argininosuccinate synthase activity
PCNPT3_RS01785	COG0165	Argininosuccinate lyase
PCNPT3_RS01785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PCNPT3_RS01795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCNPT3_RS01825	COG1607	acyl-coa hydrolase
PCNPT3_RS01830	COG0248	Ppx GppA phosphatase
PCNPT3_RS01835	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS01840	COG2814	Major facilitator Superfamily
PCNPT3_RS01850	COG3118	belongs to the thioredoxin family
PCNPT3_RS01855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PCNPT3_RS01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PCNPT3_RS01880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCNPT3_RS01880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCNPT3_RS01895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PCNPT3_RS01900	COG1357	PFAM Pentapeptide repeats (8 copies)
PCNPT3_RS01915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCNPT3_RS01920	COG3091	SprT-like family
PCNPT3_RS01925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PCNPT3_RS01930	COG0739	heme binding
PCNPT3_RS01940	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PCNPT3_RS01945	COG2816	NAD+ diphosphatase activity
PCNPT3_RS01950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PCNPT3_RS01955	COG0138	bifunctional purine biosynthesis protein purh
PCNPT3_RS01960	COG0151	Belongs to the GarS family
PCNPT3_RS01975	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PCNPT3_RS01990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PCNPT3_RS02005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PCNPT3_RS02010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PCNPT3_RS02015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PCNPT3_RS02020	COG2900	Belongs to the SlyX family
PCNPT3_RS02030	COG0545	Peptidyl-prolyl cis-trans isomerase
PCNPT3_RS02035	COG2081	HI0933 family
PCNPT3_RS02065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PCNPT3_RS02070	COG1454	alcohol dehydrogenase
PCNPT3_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
PCNPT3_RS02075	COG0628	permease
PCNPT3_RS02080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PCNPT3_RS02085	COG0857	belongs to the CobB CobQ family
PCNPT3_RS02085	COG0280	phosphate acetyltransferase
PCNPT3_RS02095	COG3092	negative regulation of chromosome organization
PCNPT3_RS02100	COG2226	methyltransferase
PCNPT3_RS02105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCNPT3_RS02110	COG1882	Formate acetyltransferase
PCNPT3_RS02120	COG4974	Belongs to the 'phage' integrase family
PCNPT3_RS02135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCNPT3_RS02140	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PCNPT3_RS02150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PCNPT3_RS02155	COG1053	succinate dehydrogenase
PCNPT3_RS02160	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PCNPT3_RS02170	COG0268	Binds directly to 16S ribosomal RNA
PCNPT3_RS02175	COG0728	peptidoglycan biosynthetic process
PCNPT3_RS02180	COG0196	riboflavin kinase activity
PCNPT3_RS02185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PCNPT3_RS02190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PCNPT3_RS02195	COG1047	Peptidyl-prolyl cis-trans
PCNPT3_RS02200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PCNPT3_RS02225	COG4969	Belongs to the N-Me-Phe pilin family
PCNPT3_RS02245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCNPT3_RS02250	COG0564	pseudouridine synthase activity
PCNPT3_RS02260	COG0542	response to heat
PCNPT3_RS02265	COG0488	(ABC) transporter
PCNPT3_RS02270	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS02280	COG0572	uridine kinase
PCNPT3_RS02285	COG0814	amino acid
PCNPT3_RS02295	COG1760	l-serine dehydratase
PCNPT3_RS02305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PCNPT3_RS02310	COG0802	atpase or kinase
PCNPT3_RS02320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PCNPT3_RS02325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PCNPT3_RS02330	COG1923	regulation of RNA biosynthetic process
PCNPT3_RS02335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCNPT3_RS02340	COG0330	HflC and HflK could
PCNPT3_RS02345	COG0330	HflC and HflK could
PCNPT3_RS02350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PCNPT3_RS02355	COG3119	arylsulfatase activity
PCNPT3_RS02365	COG0142	geranyltranstransferase activity
PCNPT3_RS02370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PCNPT3_RS02375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PCNPT3_RS02380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PCNPT3_RS02385	COG0668	transmembrane transport
PCNPT3_RS02390	COG3437	response regulator, receiver
PCNPT3_RS02390	COG3850	Histidine kinase
PCNPT3_RS02390	COG2205	protein histidine kinase activity
PCNPT3_RS02390	COG4999	Histidine kinase
PCNPT3_RS02395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCNPT3_RS02400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCNPT3_RS02425	COG0640	Transcriptional regulator
PCNPT3_RS02430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PCNPT3_RS02435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PCNPT3_RS02440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PCNPT3_RS02445	COG0745	RESPONSE REGULATOR receiver
PCNPT3_RS02455	COG1045	serine acetyltransferase
PCNPT3_RS02465	COG3074	FtsZ-dependent cytokinesis
PCNPT3_RS02470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PCNPT3_RS02475	COG2027	D-alanyl-D-alanine carboxypeptidase
PCNPT3_RS02490	COG2267	carboxylic ester hydrolase activity
PCNPT3_RS02495	COG0442	prolyl-tRNA aminoacylation
PCNPT3_RS02505	COG1720	tRNA m6t6A37 methyltransferase activity
PCNPT3_RS02515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PCNPT3_RS02540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PCNPT3_RS02545	COG2153	protein acetylation
PCNPT3_RS02555	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PCNPT3_RS02560	COG0540	Belongs to the ATCase OTCase family
PCNPT3_RS02565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PCNPT3_RS02570	COG0549	Belongs to the carbamate kinase family
PCNPT3_RS02575	COG2235	arginine
PCNPT3_RS02580	COG1288	antiporter activity
PCNPT3_RS02585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCNPT3_RS02590	COG0287	Prephenate dehydrogenase
PCNPT3_RS02590	COG1605	Chorismate mutase
PCNPT3_RS02595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCNPT3_RS02605	COG1438	arginine binding
PCNPT3_RS02610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCNPT3_RS02615	COG0039	L-malate dehydrogenase activity
PCNPT3_RS02620	COG1648	precorrin-2 dehydrogenase activity
PCNPT3_RS02620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PCNPT3_RS02630	COG1017	nitric oxide dioxygenase activity
PCNPT3_RS02630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCNPT3_RS02635	COG1959	2 iron, 2 sulfur cluster binding
PCNPT3_RS02640	COG3069	C4-dicarboxylate transmembrane transporter activity
PCNPT3_RS02650	COG0210	DNA helicase
PCNPT3_RS02655	COG1027	Aspartate ammonia-lyase
PCNPT3_RS02680	COG0358	DNA primase activity
PCNPT3_RS02690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PCNPT3_RS02695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PCNPT3_RS02710	COG0084	hydrolase, TatD family'
PCNPT3_RS02715	COG0805	protein transport
PCNPT3_RS02720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCNPT3_RS02725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCNPT3_RS02730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PCNPT3_RS02740	COG2226	methyltransferase
PCNPT3_RS02745	COG0166	Belongs to the GPI family
PCNPT3_RS02760	COG3642	lipopolysaccharide core region biosynthetic process
PCNPT3_RS02765	COG0463	Glycosyl transferase, family 2
PCNPT3_RS02770	COG0859	PFAM glycosyl transferase family 9
PCNPT3_RS02775	COG1519	Transferase
PCNPT3_RS02780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCNPT3_RS02785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCNPT3_RS02795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCNPT3_RS02800	COG3250	beta-galactosidase activity
PCNPT3_RS02805	COG0531	amino acid
PCNPT3_RS02810	COG0606	chelatase, subunit chli
PCNPT3_RS02825	COG1288	antiporter activity
PCNPT3_RS02830	COG0525	valine-tRNA ligase activity
PCNPT3_RS02835	COG2927	DNA polymerase III (CHI subunit)
PCNPT3_RS02840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PCNPT3_RS02845	COG0795	lipopolysaccharide-transporting ATPase activity
PCNPT3_RS02850	COG0795	lipopolysaccharide-transporting ATPase activity
PCNPT3_RS02885	COG0254	rRNA binding
PCNPT3_RS02890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PCNPT3_RS02905	COG1368	sulfuric ester hydrolase activity
PCNPT3_RS02910	COG0316	Belongs to the HesB IscA family
PCNPT3_RS02915	COG0719	Fe-S assembly protein
PCNPT3_RS02920	COG0396	ATPase activity
PCNPT3_RS02925	COG0719	Fe-S assembly protein
PCNPT3_RS02940	COG0697	spore germination
PCNPT3_RS02950	COG0742	ribosomal rna small subunit methyltransferase
PCNPT3_RS02955	COG0552	protein localization to endoplasmic reticulum
PCNPT3_RS02960	COG2884	Cell division ATP-binding protein ftsE
PCNPT3_RS02965	COG2177	Part of the ABC transporter FtsEX involved in
PCNPT3_RS02980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCNPT3_RS02985	COG1605	Chorismate mutase
PCNPT3_RS02985	COG0077	Prephenate dehydratase
PCNPT3_RS03025	COG2866	Carboxypeptidase
PCNPT3_RS03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PCNPT3_RS03035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCNPT3_RS03040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PCNPT3_RS03045	COG1418	mRNA catabolic process
PCNPT3_RS03050	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PCNPT3_RS03055	COG0686	Belongs to the AlaDH PNT family
PCNPT3_RS03060	COG1770	oligopeptidase
PCNPT3_RS03065	COG1823	symporter activity
PCNPT3_RS03070	COG0724	RNA recognition motif
PCNPT3_RS03075	COG0481	GTPase activity
PCNPT3_RS03080	COG0681	Belongs to the peptidase S26 family
PCNPT3_RS03085	COG0571	ribonuclease III activity
PCNPT3_RS03095	COG1381	Involved in DNA repair and RecF pathway recombination
PCNPT3_RS03100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PCNPT3_RS03105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCNPT3_RS03110	COG0733	neurotransmitter:sodium symporter activity
PCNPT3_RS03115	COG3956	TIGRFAM MazG family protein
PCNPT3_RS03120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PCNPT3_RS03125	COG1242	4 iron, 4 sulfur cluster binding
PCNPT3_RS03135	COG0784	Response regulator, receiver
PCNPT3_RS03135	COG3437	response regulator, receiver
PCNPT3_RS03140	COG2960	long-chain fatty acid transporting porin activity
PCNPT3_RS03150	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PCNPT3_RS03160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCNPT3_RS03165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PCNPT3_RS03170	COG0038	chloride channel
PCNPT3_RS03180	COG0316	Belongs to the HesB IscA family
PCNPT3_RS03190	COG0735	belongs to the Fur family
PCNPT3_RS03195	COG0716	FMN binding
PCNPT3_RS03210	COG0596	Alpha beta hydrolase
PCNPT3_RS03215	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PCNPT3_RS03220	COG0033	Phosphoglucomutase
PCNPT3_RS03230	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS03240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PCNPT3_RS03275	COG0784	Response regulator, receiver
PCNPT3_RS03275	COG0835	chemotaxis
PCNPT3_RS03280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PCNPT3_RS03285	COG1815	bacterial-type flagellum-dependent cell motility
PCNPT3_RS03290	COG1558	bacterial-type flagellum-dependent cell motility
PCNPT3_RS03295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PCNPT3_RS03300	COG1749	Flagellar hook protein flgE
PCNPT3_RS03305	COG4786	Flagellar basal body rod
PCNPT3_RS03310	COG4786	Flagellar basal body rod
PCNPT3_RS03315	COG1706	bacterial-type flagellum-dependent cell motility
PCNPT3_RS03320	COG2056	Na+-H+ antiporter family
PCNPT3_RS03325	COG1705	Flagellar rod assembly protein muramidase FlgJ
PCNPT3_RS03325	COG3951	Flagellar rod assembly protein muramidase FlgJ
PCNPT3_RS03365	COG2186	Transcriptional regulator
PCNPT3_RS03370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PCNPT3_RS03375	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCNPT3_RS03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCNPT3_RS03385	COG1187	pseudouridine synthase activity
PCNPT3_RS03395	COG0070	glutamate synthase
PCNPT3_RS03395	COG0069	glutamate synthase activity
PCNPT3_RS03395	COG0067	glutamate synthase
PCNPT3_RS03405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PCNPT3_RS03410	COG0602	queuosine metabolic process
PCNPT3_RS03415	COG1643	Atp-dependent helicase
PCNPT3_RS03425	COG0745	RESPONSE REGULATOR receiver
PCNPT3_RS03440	COG0788	formyltetrahydrofolate deformylase activity
PCNPT3_RS03445	COG3012	SEC-C Motif Domain Protein
PCNPT3_RS03450	COG0367	asparagine synthase
PCNPT3_RS03465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCNPT3_RS03470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCNPT3_RS03485	COG0583	DNA-binding transcription factor activity
PCNPT3_RS03490	COG1785	Belongs to the alkaline phosphatase family
PCNPT3_RS03510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PCNPT3_RS03515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PCNPT3_RS03520	COG0569	domain protein
PCNPT3_RS03525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCNPT3_RS03530	COG1077	Cell shape determining protein MreB Mrl
PCNPT3_RS03535	COG1792	Involved in formation and maintenance of cell shape
PCNPT3_RS03540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PCNPT3_RS03545	COG0424	maF-like protein
PCNPT3_RS03550	COG1530	ribonuclease E activity
PCNPT3_RS03555	COG3164	Protein of unknown function
PCNPT3_RS03560	COG0312	modulator of DNA gyrase
PCNPT3_RS03565	COG0659	secondary active sulfate transmembrane transporter activity
PCNPT3_RS03570	COG2814	Major facilitator Superfamily
PCNPT3_RS03575	COG0583	DNA-binding transcription factor activity
PCNPT3_RS03580	COG0840	transmembrane signaling receptor activity
PCNPT3_RS03585	COG3028	Belongs to the UPF0307 family
PCNPT3_RS03590	COG0312	modulator of DNA gyrase
PCNPT3_RS03595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PCNPT3_RS03600	COG0772	Belongs to the SEDS family
PCNPT3_RS03605	COG0768	penicillin binding
PCNPT3_RS03610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PCNPT3_RS03615	COG0799	negative regulation of ribosome biogenesis
PCNPT3_RS03620	COG2001	Belongs to the MraZ family
PCNPT3_RS03625	COG0275	rRNA processing
PCNPT3_RS03630	COG3116	cell division
PCNPT3_RS03635	COG0768	penicillin binding
PCNPT3_RS03645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PCNPT3_RS03650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCNPT3_RS03660	COG0772	Belongs to the SEDS family
PCNPT3_RS03665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PCNPT3_RS03670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PCNPT3_RS03675	COG1181	Belongs to the D-alanine--D-alanine ligase family
PCNPT3_RS03685	COG0849	cell division
PCNPT3_RS03690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PCNPT3_RS03695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PCNPT3_RS03705	COG0739	heme binding
PCNPT3_RS03710	COG0653	protein targeting
PCNPT3_RS03715	COG0494	nUDIX hydrolase
PCNPT3_RS03725	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PCNPT3_RS03725	COG0237	dephospho-CoA kinase activity
PCNPT3_RS03735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PCNPT3_RS03740	COG0023	Translation Initiation Factor
PCNPT3_RS03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PCNPT3_RS03760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PCNPT3_RS03765	COG3063	Type IV pilus biogenesis stability protein PilW
PCNPT3_RS03770	COG1426	Protein conserved in bacteria
PCNPT3_RS03775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PCNPT3_RS03780	COG0124	histidyl-tRNA synthetase
PCNPT3_RS03785	COG2976	Protein conserved in bacteria
PCNPT3_RS03790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCNPT3_RS03795	COG1160	GTP binding
PCNPT3_RS03805	COG2823	Periplasmic or secreted lipoprotein
PCNPT3_RS03810	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PCNPT3_RS03815	COG0792	nuclease activity
PCNPT3_RS03820	COG3107	peptidoglycan biosynthetic process
PCNPT3_RS03825	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PCNPT3_RS03850	COG0095	Lipoate-protein ligase
PCNPT3_RS03855	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS03875	COG0604	alcohol dehydrogenase
PCNPT3_RS03890	COG2855	membrane
PCNPT3_RS03895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PCNPT3_RS03900	COG1466	dna polymerase III delta subunit
PCNPT3_RS03910	COG0495	leucyl-tRNA aminoacylation
PCNPT3_RS03915	COG0840	transmembrane signaling receptor activity
PCNPT3_RS03920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PCNPT3_RS03930	COG2197	response regulator
PCNPT3_RS03945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
PCNPT3_RS03945	COG3408	Glycogen debranching enzyme
PCNPT3_RS03965	COG0745	RESPONSE REGULATOR receiver
PCNPT3_RS03975	COG0083	homoserine kinase activity
PCNPT3_RS03980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PCNPT3_RS03985	COG1946	Acyl-CoA thioesterase
PCNPT3_RS03990	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PCNPT3_RS03995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PCNPT3_RS04000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PCNPT3_RS04005	COG1678	Uncharacterized ACR, COG1678
PCNPT3_RS04010	COG0189	ligase activity
PCNPT3_RS04015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PCNPT3_RS04020	COG2966	Psort location CytoplasmicMembrane, score
PCNPT3_RS04025	COG3610	response to peptide
PCNPT3_RS04030	COG0653	protein targeting
PCNPT3_RS04045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PCNPT3_RS04050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PCNPT3_RS04055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PCNPT3_RS04060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCNPT3_RS04065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PCNPT3_RS04070	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PCNPT3_RS04075	COG2171	N-acyltransferase activity
PCNPT3_RS04095	COG2350	Protein conserved in bacteria
PCNPT3_RS04100	COG2917	probably involved in intracellular septation
PCNPT3_RS04110	COG0133	tryptophan synthase activity
PCNPT3_RS04115	COG0135	phosphoribosylanthranilate isomerase activity
PCNPT3_RS04115	COG0134	indole-3-glycerol-phosphate synthase activity
PCNPT3_RS04120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCNPT3_RS04125	COG0512	Glutamine amidotransferase of anthranilate synthase
PCNPT3_RS04130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCNPT3_RS04135	COG0613	PHP domain protein
PCNPT3_RS04140	COG0009	L-threonylcarbamoyladenylate synthase
PCNPT3_RS04145	COG1187	pseudouridine synthase activity
PCNPT3_RS04155	COG1380	Effector of murein hydrolase LrgA
PCNPT3_RS04160	COG1346	cytolysis
PCNPT3_RS04165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCNPT3_RS04170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PCNPT3_RS04190	COG1393	Belongs to the ArsC family
PCNPT3_RS04195	COG2983	Belongs to the UPF0260 family
PCNPT3_RS04200	COG2951	lytic endotransglycosylase activity
PCNPT3_RS04205	COG3100	YcgL domain-containing protein
PCNPT3_RS04215	COG2894	cell division
PCNPT3_RS04220	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PCNPT3_RS04235	COG0556	nucleotide-excision repair
PCNPT3_RS04240	COG0424	maF-like protein
PCNPT3_RS04245	COG1399	metal-binding, possibly nucleic acid-binding protein
PCNPT3_RS04250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PCNPT3_RS04255	COG0416	fatty acid biosynthetic process
PCNPT3_RS04260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCNPT3_RS04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCNPT3_RS04280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCNPT3_RS04285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PCNPT3_RS04290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PCNPT3_RS04295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PCNPT3_RS04300	COG0470	DNA polymerase III
PCNPT3_RS04305	COG0084	hydrolase, TatD family'
PCNPT3_RS04310	COG2195	Cleaves the N-terminal amino acid of tripeptides
PCNPT3_RS04315	COG2195	Cleaves the N-terminal amino acid of tripeptides
PCNPT3_RS04320	COG0505	Belongs to the CarA family
PCNPT3_RS04325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PCNPT3_RS04330	COG1280	lysine exporter protein (LysE YggA)
PCNPT3_RS04335	COG1454	alcohol dehydrogenase
PCNPT3_RS04350	COG2333	competence protein COMEC
PCNPT3_RS04350	COG0658	competence protein
PCNPT3_RS04360	COG1663	tetraacyldisaccharide 4'-kinase activity
PCNPT3_RS04365	COG2835	tetraacyldisaccharide 4'-kinase activity
PCNPT3_RS04370	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PCNPT3_RS04385	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PCNPT3_RS04390	COG0659	secondary active sulfate transmembrane transporter activity
PCNPT3_RS04400	COG0205	6-phosphofructokinase activity
PCNPT3_RS04410	COG0564	pseudouridine synthase activity
PCNPT3_RS04415	COG0708	Exodeoxyribonuclease III
PCNPT3_RS04425	COG0483	inositol monophosphate 1-phosphatase activity
PCNPT3_RS04435	COG1959	2 iron, 2 sulfur cluster binding
PCNPT3_RS04440	COG1104	cysteine desulfurase activity
PCNPT3_RS04445	COG0822	iron-sulfur transferase activity
PCNPT3_RS04455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PCNPT3_RS04460	COG0443	Heat shock 70 kDa protein
PCNPT3_RS04480	COG0601	transmembrane transport
PCNPT3_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCNPT3_RS04505	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PCNPT3_RS04510	COG0121	glutamine amidotransferase
PCNPT3_RS04515	COG0789	Transcriptional regulator
PCNPT3_RS04525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PCNPT3_RS04530	COG4221	oxidoreductase activity
PCNPT3_RS04535	COG2095	MarC family integral membrane protein
PCNPT3_RS04540	COG3314	Sporulation integral membrane protein YlbJ
PCNPT3_RS04545	COG3706	GGDEF domain
PCNPT3_RS04550	COG0179	Fumarylacetoacetate (FAA) hydrolase
PCNPT3_RS04555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PCNPT3_RS04560	COG0072	phenylalanine-tRNA ligase activity
PCNPT3_RS04560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS04565	COG0776	regulation of translation
PCNPT3_RS04570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PCNPT3_RS04600	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PCNPT3_RS04605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PCNPT3_RS04610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PCNPT3_RS04615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCNPT3_RS04615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCNPT3_RS04625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PCNPT3_RS04630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCNPT3_RS04695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PCNPT3_RS04700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCNPT3_RS04820	COG1280	lysine exporter protein (LysE YggA)
PCNPT3_RS04830	COG0393	Putative heavy-metal-binding
PCNPT3_RS04845	COG3594	Acyltransferase
PCNPT3_RS04865	COG0393	Putative heavy-metal-binding
PCNPT3_RS04915	COG1794	racemase activity, acting on amino acids and derivatives
PCNPT3_RS04920	COG0583	DNA-binding transcription factor activity
PCNPT3_RS04970	COG2258	MOSC domain
PCNPT3_RS04990	COG1742	UPF0060 membrane protein
PCNPT3_RS05020	COG0531	amino acid
PCNPT3_RS05025	COG1609	Transcriptional regulator
PCNPT3_RS05030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS05055	COG2223	nitrite transmembrane transporter activity
PCNPT3_RS05060	COG3279	Response regulator of the LytR AlgR family
PCNPT3_RS05065	COG3275	phosphorelay sensor kinase activity
PCNPT3_RS05075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCNPT3_RS05085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS05085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS05090	COG0489	protein tyrosine kinase activity
PCNPT3_RS05095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PCNPT3_RS05130	COG1979	alcohol dehydrogenase
PCNPT3_RS05140	COG2130	NADP-dependent
PCNPT3_RS05145	COG1309	transcriptional regulator
PCNPT3_RS05150	COG2271	Major facilitator Superfamily
PCNPT3_RS05160	COG2197	response regulator
PCNPT3_RS05190	COG0641	radical SAM
PCNPT3_RS05195	COG3119	arylsulfatase activity
PCNPT3_RS05200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCNPT3_RS05205	COG3122	Protein conserved in bacteria
PCNPT3_RS05220	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PCNPT3_RS05225	COG0372	Belongs to the citrate synthase family
PCNPT3_RS05235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PCNPT3_RS05240	COG1053	succinate dehydrogenase
PCNPT3_RS05250	COG0567	Dehydrogenase, E1 component
PCNPT3_RS05255	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCNPT3_RS05260	COG0045	succinate-CoA ligase (ADP-forming) activity
PCNPT3_RS05265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PCNPT3_RS05280	COG4628	conserved protein (DUF2132)
PCNPT3_RS05305	COG4628	conserved protein (DUF2132)
PCNPT3_RS05315	COG0301	tRNA thio-modification
PCNPT3_RS05315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCNPT3_RS05320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PCNPT3_RS05325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PCNPT3_RS05335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCNPT3_RS05335	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PCNPT3_RS05340	COG3008	intermembrane lipid transfer
PCNPT3_RS05345	COG2995	paraquat-inducible protein a
PCNPT3_RS05355	COG3141	response to X-ray
PCNPT3_RS05360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PCNPT3_RS05365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PCNPT3_RS05370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PCNPT3_RS05375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PCNPT3_RS05385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PCNPT3_RS05390	COG0343	queuine tRNA-ribosyltransferase activity
PCNPT3_RS05395	COG1862	Preprotein translocase
PCNPT3_RS05400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCNPT3_RS05405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCNPT3_RS05420	COG1086	Polysaccharide biosynthesis protein
PCNPT3_RS05425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PCNPT3_RS05430	COG1083	cytidylyl-transferase
PCNPT3_RS05440	COG2089	acid synthase
PCNPT3_RS05445	COG0492	ferredoxin-NADP+ reductase activity
PCNPT3_RS05450	COG1530	ribonuclease E activity
PCNPT3_RS05455	COG0564	pseudouridine synthase activity
PCNPT3_RS05460	COG0546	phosphoglycolate phosphatase activity
PCNPT3_RS05465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCNPT3_RS05480	COG2356	endonuclease I
PCNPT3_RS05485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCNPT3_RS05490	COG0676	glucose-6-phosphate 1-epimerase activity
PCNPT3_RS05505	COG0469	pyruvate kinase activity
PCNPT3_RS05510	COG1737	Transcriptional regulator
PCNPT3_RS05515	COG0837	glucose binding
PCNPT3_RS05530	COG0840	transmembrane signaling receptor activity
PCNPT3_RS05535	COG2885	chlorophyll binding
PCNPT3_RS05535	COG3047	cAMP biosynthetic process
PCNPT3_RS05590	COG2194	sulfuric ester hydrolase activity
PCNPT3_RS05595	COG0583	DNA-binding transcription factor activity
PCNPT3_RS05600	COG3791	Glutathione-dependent formaldehyde-activating
PCNPT3_RS05605	COG2964	Protein conserved in bacteria
PCNPT3_RS05610	COG3681	Belongs to the UPF0597 family
PCNPT3_RS05615	COG0251	oxidation-reduction process
PCNPT3_RS05620	COG0814	amino acid
PCNPT3_RS05655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PCNPT3_RS05660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PCNPT3_RS05695	COG1280	lysine exporter protein (LysE YggA)
PCNPT3_RS05710	COG2249	NAD(P)H dehydrogenase (quinone) activity
PCNPT3_RS05715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PCNPT3_RS05720	COG0583	DNA-binding transcription factor activity
PCNPT3_RS05730	COG1213	nucleotidyl transferase
PCNPT3_RS05740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PCNPT3_RS05750	COG3457	Alanine racemase
PCNPT3_RS05755	COG1288	antiporter activity
PCNPT3_RS05770	COG0519	Catalyzes the synthesis of GMP from XMP
PCNPT3_RS05775	COG1289	transmembrane transporter activity
PCNPT3_RS05800	COG1116	anion transmembrane transporter activity
PCNPT3_RS05805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCNPT3_RS05810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCNPT3_RS05815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PCNPT3_RS05825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PCNPT3_RS05830	COG2186	Transcriptional regulator
PCNPT3_RS05840	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PCNPT3_RS05845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PCNPT3_RS05850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCNPT3_RS05855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PCNPT3_RS05895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PCNPT3_RS05900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCNPT3_RS05905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PCNPT3_RS05910	COG2974	May be involved in recombination
PCNPT3_RS05915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PCNPT3_RS05920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCNPT3_RS05950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PCNPT3_RS05955	COG1085	galactose-1-phosphate uridylyltransferase
PCNPT3_RS05960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PCNPT3_RS05965	COG2017	converts alpha-aldose to the beta-anomer
PCNPT3_RS05970	COG1869	D-ribose catabolic process
PCNPT3_RS05975	COG1129	ABC transporter
PCNPT3_RS05980	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCNPT3_RS05985	COG1879	ABC-type sugar transport system periplasmic component
PCNPT3_RS05990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCNPT3_RS06000	COG2814	Major facilitator Superfamily
PCNPT3_RS06005	COG0443	Heat shock 70 kDa protein
PCNPT3_RS06010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCNPT3_RS06015	COG2137	regulation of response to DNA damage stimulus
PCNPT3_RS06025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PCNPT3_RS06030	COG1362	aminopeptidase activity
PCNPT3_RS06040	COG0484	heat shock protein binding
PCNPT3_RS06070	COG0217	transcriptional regulatory protein
PCNPT3_RS06080	COG1451	nucleotide metabolic process
PCNPT3_RS06085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCNPT3_RS06090	COG0318	PFAM AMP-dependent synthetase and ligase
PCNPT3_RS06095	COG0596	Alpha beta hydrolase
PCNPT3_RS06100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCNPT3_RS06105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCNPT3_RS06105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PCNPT3_RS06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCNPT3_RS06115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PCNPT3_RS06120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCNPT3_RS06130	COG1472	Belongs to the glycosyl hydrolase 3 family
PCNPT3_RS06135	COG3150	esterase
PCNPT3_RS06140	COG1252	NADH dehydrogenase
PCNPT3_RS06145	COG0471	metal ion transport
PCNPT3_RS06150	COG0616	signal peptide processing
PCNPT3_RS06155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PCNPT3_RS06160	COG1067	ATP-dependent peptidase activity
PCNPT3_RS06195	COG1448	Aminotransferase
PCNPT3_RS06200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCNPT3_RS06205	COG0730	response to heat
PCNPT3_RS06210	COG1560	Kdo2-lipid A biosynthetic process
PCNPT3_RS06215	COG1028	Short-chain dehydrogenase reductase Sdr
PCNPT3_RS06220	COG0616	signal peptide processing
PCNPT3_RS06225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCNPT3_RS06230	COG0101	tRNA pseudouridine synthase activity
PCNPT3_RS06235	COG0285	dihydrofolate synthase activity
PCNPT3_RS06245	COG1286	toxin biosynthetic process
PCNPT3_RS06250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCNPT3_RS06255	COG0017	Asparaginyl-tRNA synthetase
PCNPT3_RS06260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PCNPT3_RS06265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PCNPT3_RS06270	COG0156	8-amino-7-oxononanoate synthase activity
PCNPT3_RS06280	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PCNPT3_RS06285	COG4143	(ABC) transporter
PCNPT3_RS06290	COG1178	ABC-type Fe3 transport system permease component
PCNPT3_RS06295	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PCNPT3_RS06310	COG1473	amidohydrolase
PCNPT3_RS06315	COG0390	transport system, permease component
PCNPT3_RS06320	COG2897	thiosulfate sulfurtransferase activity
PCNPT3_RS06330	COG0840	transmembrane signaling receptor activity
PCNPT3_RS06340	COG0840	transmembrane signaling receptor activity
PCNPT3_RS06345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS06345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCNPT3_RS06360	COG0402	S-adenosylhomocysteine deaminase activity
PCNPT3_RS06380	COG1054	Belongs to the UPF0176 family
PCNPT3_RS06430	COG0405	Gamma-glutamyltransferase
PCNPT3_RS06460	COG2801	Transposase and inactivated derivatives
PCNPT3_RS06505	COG1121	(ABC) transporter
PCNPT3_RS06510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCNPT3_RS06515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCNPT3_RS06525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PCNPT3_RS06530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PCNPT3_RS06535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCNPT3_RS06550	COG2384	SAM-dependent methyltransferase
PCNPT3_RS06555	COG2183	response to ionizing radiation
PCNPT3_RS06560	COG0673	inositol 2-dehydrogenase activity
PCNPT3_RS06575	COG2116	formate transmembrane transporter activity
PCNPT3_RS06580	COG0583	DNA-binding transcription factor activity
PCNPT3_RS06585	COG1966	Carbon starvation protein
PCNPT3_RS06590	COG3279	Response regulator of the LytR AlgR family
PCNPT3_RS06595	COG3275	phosphorelay sensor kinase activity
PCNPT3_RS06600	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS06605	COG2911	Protein conserved in bacteria
PCNPT3_RS06610	COG0729	surface antigen
PCNPT3_RS06625	COG0501	Belongs to the peptidase M48B family
PCNPT3_RS06630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCNPT3_RS06635	COG3154	lipid carrier protein
PCNPT3_RS06640	COG0826	peptidase U32
PCNPT3_RS06645	COG0826	peptidase U32
PCNPT3_RS06655	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PCNPT3_RS06670	COG0314	molybdopterin synthase activity
PCNPT3_RS06675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PCNPT3_RS06680	COG0315	cyclic pyranopterin monophosphate synthase activity
PCNPT3_RS06685	COG0521	Mo-molybdopterin cofactor biosynthetic process
PCNPT3_RS06690	COG0746	molybdenum cofactor guanylyltransferase activity
PCNPT3_RS06695	COG3005	denitrification pathway
PCNPT3_RS06700	COG3043	anaerobic respiration
PCNPT3_RS06705	COG0243	molybdopterin cofactor binding
PCNPT3_RS06710	COG3062	negative regulation of establishment of protein localization
PCNPT3_RS06715	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCNPT3_RS06715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCNPT3_RS06720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PCNPT3_RS06725	COG3850	Histidine kinase
PCNPT3_RS06730	COG2197	response regulator
PCNPT3_RS06735	COG1199	ATP-dependent helicase activity
PCNPT3_RS06740	COG0730	response to heat
PCNPT3_RS06750	COG1254	Belongs to the acylphosphatase family
PCNPT3_RS06755	COG0215	cysteine-tRNA ligase activity
PCNPT3_RS06760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCNPT3_RS06765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCNPT3_RS06770	COG0583	DNA-binding transcription factor activity
PCNPT3_RS06780	COG1566	PFAM secretion protein HlyD family protein
PCNPT3_RS06785	COG2814	Major facilitator Superfamily
PCNPT3_RS06790	COG0793	Belongs to the peptidase S41A family
PCNPT3_RS06795	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PCNPT3_RS06800	COG0826	peptidase U32
PCNPT3_RS06805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCNPT3_RS06815	COG4166	transmembrane transport
PCNPT3_RS06820	COG4168	peptide transport system, permease
PCNPT3_RS06825	COG4171	peptide transport system, permease
PCNPT3_RS06830	COG4172	Belongs to the ABC transporter superfamily
PCNPT3_RS06835	COG4172	Belongs to the ABC transporter superfamily
PCNPT3_RS06840	COG0037	tRNA processing
PCNPT3_RS06845	COG0149	triose-phosphate isomerase activity
PCNPT3_RS06850	COG0670	Belongs to the BI1 family
PCNPT3_RS06855	COG1733	regulation of RNA biosynthetic process
PCNPT3_RS06860	COG1012	belongs to the aldehyde dehydrogenase family
PCNPT3_RS06920	COG2944	sequence-specific DNA binding
PCNPT3_RS06925	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
PCNPT3_RS06940	COG1187	pseudouridine synthase activity
PCNPT3_RS06945	COG4591	ABC-type transport system involved in lipoprotein release permease component
PCNPT3_RS06950	COG1136	(ABC) transporter
PCNPT3_RS06965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCNPT3_RS06975	COG0826	peptidase U32
PCNPT3_RS06980	COG4628	conserved protein (DUF2132)
PCNPT3_RS06985	COG2070	2-Nitropropane dioxygenase
PCNPT3_RS06985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PCNPT3_RS07000	COG0604	alcohol dehydrogenase
PCNPT3_RS07000	COG3321	synthase
PCNPT3_RS07015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCNPT3_RS07025	COG0318	PFAM AMP-dependent synthetase and ligase
PCNPT3_RS07035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PCNPT3_RS07045	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PCNPT3_RS07050	COG2204	response regulator
PCNPT3_RS07055	COG0308	aminopeptidase N
PCNPT3_RS07060	COG0534	Mate efflux family protein
PCNPT3_RS07065	COG0417	DNA replication proofreading
PCNPT3_RS07070	COG1022	Amp-dependent synthetase and ligase
PCNPT3_RS07075	COG0183	Belongs to the thiolase family
PCNPT3_RS07080	COG1024	Enoyl-CoA hydratase
PCNPT3_RS07080	COG1250	3-hydroxyacyl-CoA dehydrogenase
PCNPT3_RS07090	COG2095	MarC family integral membrane protein
PCNPT3_RS07095	COG1063	alcohol dehydrogenase
PCNPT3_RS07100	COG0156	8-amino-7-oxononanoate synthase activity
PCNPT3_RS07110	COG1061	Type III restriction enzyme res subunit
PCNPT3_RS07125	COG0246	Mannitol dehydrogenase
PCNPT3_RS07135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PCNPT3_RS07145	COG2186	Transcriptional regulator
PCNPT3_RS07150	COG1312	Catalyzes the dehydration of D-mannonate
PCNPT3_RS07180	COG1940	carbohydrate kinase activity
PCNPT3_RS07190	COG0789	Transcriptional regulator
PCNPT3_RS07195	COG0701	Predicted permease
PCNPT3_RS07215	COG3119	arylsulfatase activity
PCNPT3_RS07220	COG0641	radical SAM
PCNPT3_RS07225	COG0714	Associated with various cellular activities
PCNPT3_RS07260	COG5492	domain, Protein
PCNPT3_RS07260	COG4932	domain protein
PCNPT3_RS07265	COG4932	domain protein
PCNPT3_RS07265	COG5492	domain, Protein
PCNPT3_RS07305	COG2925	Exonuclease
PCNPT3_RS07315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PCNPT3_RS07320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCNPT3_RS07325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCNPT3_RS07330	COG2190	(PTS) system
PCNPT3_RS07335	COG1393	Belongs to the ArsC family
PCNPT3_RS07340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PCNPT3_RS07345	COG1876	peptidase activity
PCNPT3_RS07360	COG0560	Phosphoserine phosphatase
PCNPT3_RS07380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCNPT3_RS07385	COG2885	chlorophyll binding
PCNPT3_RS07395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PCNPT3_RS07405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCNPT3_RS07415	COG1666	GTP binding
PCNPT3_RS07440	COG0537	adenosine 5'-monophosphoramidase activity
PCNPT3_RS07450	COG3081	Nucleoid-associated protein
PCNPT3_RS07455	COG3082	Protein of unknown function (DUF1414)
PCNPT3_RS07460	COG3083	sulfuric ester hydrolase activity
PCNPT3_RS07475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCNPT3_RS07480	COG1120	ATPase activity
PCNPT3_RS07490	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PCNPT3_RS07505	COG0747	negative chemotaxis
PCNPT3_RS07510	COG0601	transmembrane transport
PCNPT3_RS07515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCNPT3_RS07520	COG1032	radical SAM domain protein
PCNPT3_RS07535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PCNPT3_RS07540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PCNPT3_RS07545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCNPT3_RS07550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PCNPT3_RS07555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCNPT3_RS07565	COG2201	protein-glutamate methylesterase activity
PCNPT3_RS07570	COG3706	GGDEF domain
PCNPT3_RS07580	COG0488	(ABC) transporter
PCNPT3_RS07590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PCNPT3_RS07590	COG0116	Belongs to the methyltransferase superfamily
PCNPT3_RS07595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PCNPT3_RS07600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PCNPT3_RS07605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PCNPT3_RS07610	COG0131	Imidazoleglycerol-phosphate dehydratase
PCNPT3_RS07610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PCNPT3_RS07615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PCNPT3_RS07620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PCNPT3_RS07625	COG0107	imidazoleglycerol-phosphate synthase activity
PCNPT3_RS07630	COG0140	phosphoribosyl-ATP diphosphatase activity
PCNPT3_RS07630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PCNPT3_RS07640	COG0446	pyridine nucleotide-disulphide oxidoreductase
PCNPT3_RS07645	COG0418	dihydroorotase activity
PCNPT3_RS07655	COG2813	Specifically methylates the guanine in position
PCNPT3_RS07665	COG0167	dihydroorotate dehydrogenase activity
PCNPT3_RS07685	COG1199	ATP-dependent helicase activity
PCNPT3_RS07700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCNPT3_RS07705	COG2011	ABC-type metal ion transport system permease component
PCNPT3_RS07710	COG1464	Belongs to the NlpA lipoprotein family
PCNPT3_RS07715	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PCNPT3_RS07725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PCNPT3_RS07730	COG2912	Transglutaminase-like superfamily
PCNPT3_RS07740	COG2890	protein-(glutamine-N5) methyltransferase activity
PCNPT3_RS07745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PCNPT3_RS07750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PCNPT3_RS07755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCNPT3_RS07760	COG2914	Belongs to the UPF0125 (RnfH) family
PCNPT3_RS07765	COG2867	negative regulation of translational initiation
PCNPT3_RS07770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PCNPT3_RS07775	COG2194	sulfuric ester hydrolase activity
PCNPT3_RS07785	COG2176	DNA-directed DNA polymerase activity
PCNPT3_RS07820	COG0697	spore germination
PCNPT3_RS07835	COG0697	spore germination
PCNPT3_RS07840	COG0500	methyltransferase
PCNPT3_RS07845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PCNPT3_RS07865	COG0129	dihydroxy-acid dehydratase activity
PCNPT3_RS07870	COG3978	acetolactate synthase activity
PCNPT3_RS07880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PCNPT3_RS07890	COG0066	3-isopropylmalate dehydratase activity
PCNPT3_RS07895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PCNPT3_RS07900	COG0473	3-isopropylmalate dehydrogenase activity
PCNPT3_RS07905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PCNPT3_RS07915	COG3304	Inner membrane component domain
PCNPT3_RS07925	COG0798	PFAM Bile acid sodium symporter
PCNPT3_RS07940	COG0583	DNA-binding transcription factor activity
PCNPT3_RS07970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PCNPT3_RS07975	COG0574	Belongs to the PEP-utilizing enzyme family
PCNPT3_RS07975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCNPT3_RS07985	COG1115	amino acid carrier protein
PCNPT3_RS07995	COG1522	sequence-specific DNA binding
PCNPT3_RS08005	COG3097	Belongs to the UPF0267 family
PCNPT3_RS08010	COG0741	lytic transglycosylase activity
PCNPT3_RS08015	COG3588	fructose-bisphosphate aldolase
PCNPT3_RS08020	COG0588	phosphoglycerate mutase activity
PCNPT3_RS08035	COG0814	amino acid
PCNPT3_RS08050	COG1263	PTS System
PCNPT3_RS08050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCNPT3_RS08055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PCNPT3_RS08065	COG0561	phosphatase activity
PCNPT3_RS08070	COG2095	MarC family integral membrane protein
PCNPT3_RS08075	COG0737	Belongs to the 5'-nucleotidase family
PCNPT3_RS08080	COG3104	oligopeptide transport
PCNPT3_RS08095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCNPT3_RS08100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PCNPT3_RS08105	COG1609	Transcriptional regulator
PCNPT3_RS08115	COG2176	DNA-directed DNA polymerase activity
PCNPT3_RS08125	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
PCNPT3_RS08130	COG1737	Transcriptional regulator
PCNPT3_RS08135	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PCNPT3_RS08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCNPT3_RS08190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PCNPT3_RS08230	COG2003	Belongs to the UPF0758 family
PCNPT3_RS08240	COG2860	membrane
PCNPT3_RS08255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PCNPT3_RS08270	COG3142	Participates in the control of copper homeostasis
PCNPT3_RS08275	COG1360	Flagellar Motor Protein
PCNPT3_RS08280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PCNPT3_RS08285	COG1722	exodeoxyribonuclease VII activity
PCNPT3_RS08290	COG0142	geranyltranstransferase activity
PCNPT3_RS08295	COG0251	oxidation-reduction process
PCNPT3_RS08300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PCNPT3_RS08310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PCNPT3_RS08315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PCNPT3_RS08345	COG2926	Belongs to the UPF0265 family
PCNPT3_RS08350	COG2091	lysine biosynthetic process via aminoadipic acid
PCNPT3_RS08370	COG3101	peptidyl-lysine hydroxylation
PCNPT3_RS08375	COG0259	pyridoxamine-phosphate oxidase activity
PCNPT3_RS08380	COG1492	cobalamin metabolic process
PCNPT3_RS08385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCNPT3_RS08390	COG0303	'Molybdopterin
PCNPT3_RS08395	COG0436	Aminotransferase
PCNPT3_RS08400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PCNPT3_RS08405	COG1289	transmembrane transporter activity
PCNPT3_RS08410	COG2920	part of a sulfur-relay system
PCNPT3_RS08415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCNPT3_RS08440	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCNPT3_RS08445	COG1263	PTS System
PCNPT3_RS08450	COG1653	transport
PCNPT3_RS08515	COG0582	viral genome integration into host DNA
PCNPT3_RS08620	COG3501	Rhs element vgr protein
PCNPT3_RS08645	COG3829	transcription factor binding
PCNPT3_RS08715	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS08725	COG1120	ATPase activity
PCNPT3_RS08735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCNPT3_RS08745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PCNPT3_RS08760	COG0494	nUDIX hydrolase
PCNPT3_RS08800	COG2026	Addiction module toxin, RelE StbE family
PCNPT3_RS08805	COG1464	Belongs to the NlpA lipoprotein family
PCNPT3_RS08815	COG0840	transmembrane signaling receptor activity
PCNPT3_RS08830	COG0251	oxidation-reduction process
PCNPT3_RS08835	COG3681	Belongs to the UPF0597 family
PCNPT3_RS08840	COG2964	Protein conserved in bacteria
PCNPT3_RS08850	COG3829	transcription factor binding
PCNPT3_RS08870	COG1131	(ABC) transporter
PCNPT3_RS08885	COG1435	thymidine kinase activity
PCNPT3_RS08890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCNPT3_RS08895	COG0776	regulation of translation
PCNPT3_RS08900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PCNPT3_RS08905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PCNPT3_RS08910	COG0740	serine-type endopeptidase activity
PCNPT3_RS08915	COG0544	peptidyl-prolyl cis-trans isomerase activity
PCNPT3_RS08920	COG2095	MarC family integral membrane protein
PCNPT3_RS08930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PCNPT3_RS08935	COG1074	ATP-dependent DNA helicase activity
PCNPT3_RS08940	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PCNPT3_RS08945	COG2996	Protein conserved in bacteria
PCNPT3_RS08950	COG2050	protein possibly involved in aromatic compounds catabolism
PCNPT3_RS08955	COG0277	FAD linked oxidase domain protein
PCNPT3_RS08955	COG0247	lactate metabolic process
PCNPT3_RS08960	COG2233	PERMEase
PCNPT3_RS08965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PCNPT3_RS09005	COG3278	Belongs to the heme-copper respiratory oxidase family
PCNPT3_RS09020	COG2010	Cytochrome c
PCNPT3_RS09030	COG2217	Heavy metal translocating P-type atpase
PCNPT3_RS09045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCNPT3_RS09050	COG0589	response to stress
PCNPT3_RS09055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCNPT3_RS09070	COG4783	chaperone-mediated protein folding
PCNPT3_RS09075	COG2198	Histidine kinase
PCNPT3_RS09075	COG5002	protein histidine kinase activity
PCNPT3_RS09075	COG0784	Response regulator, receiver
PCNPT3_RS09080	COG1469	GTP cyclohydrolase I activity
PCNPT3_RS09095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PCNPT3_RS09105	COG0545	Peptidyl-prolyl cis-trans isomerase
PCNPT3_RS09110	COG0484	heat shock protein binding
PCNPT3_RS09115	COG0443	Heat shock 70 kDa protein
PCNPT3_RS09120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PCNPT3_RS09125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PCNPT3_RS09130	COG0497	DNA recombination
PCNPT3_RS09135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PCNPT3_RS09140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PCNPT3_RS09145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCNPT3_RS09150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PCNPT3_RS09155	COG0193	aminoacyl-tRNA hydrolase activity
PCNPT3_RS09160	COG0012	GTP binding
PCNPT3_RS09170	COG1349	DNA-binding transcription factor activity
PCNPT3_RS09175	COG0110	maltose O-acetyltransferase activity
PCNPT3_RS09180	COG0419	ATPase involved in DNA repair
PCNPT3_RS09185	COG0420	3'-5' exonuclease activity
PCNPT3_RS09235	COG0784	Response regulator, receiver
PCNPT3_RS09235	COG0835	chemotaxis
PCNPT3_RS09255	COG3038	cytochrome b561
PCNPT3_RS09260	COG2353	YceI-like domain
PCNPT3_RS09275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PCNPT3_RS09280	COG2890	protein-(glutamine-N5) methyltransferase activity
PCNPT3_RS09285	COG2840	Smr protein MutS2
PCNPT3_RS09290	COG2062	phosphohistidine phosphatase, SixA
PCNPT3_RS09295	COG0714	Associated with various cellular activities
PCNPT3_RS09310	COG2304	oxidoreductase activity
PCNPT3_RS09315	COG2304	oxidoreductase activity
PCNPT3_RS09325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCNPT3_RS09330	COG4597	amino acid ABC transporter
PCNPT3_RS09335	COG0765	amino acid transport
PCNPT3_RS09340	COG1126	abc transporter atp-binding protein
PCNPT3_RS09345	COG1584	GPR1 FUN34 yaaH family protein
PCNPT3_RS09375	COG1185	polyribonucleotide nucleotidyltransferase activity
PCNPT3_RS09380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PCNPT3_RS09385	COG0814	amino acid
PCNPT3_RS09395	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PCNPT3_RS09400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PCNPT3_RS09405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PCNPT3_RS09405	COG3064	Membrane
PCNPT3_RS09410	COG0195	Participates in both transcription termination and antitermination
PCNPT3_RS09415	COG0779	Required for maturation of 30S ribosomal subunits
PCNPT3_RS09430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PCNPT3_RS09435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCNPT3_RS09440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PCNPT3_RS09450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PCNPT3_RS09455	COG1534	Rna-binding protein
PCNPT3_RS09460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PCNPT3_RS09465	COG0084	hydrolase, TatD family'
PCNPT3_RS09470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PCNPT3_RS09475	COG0724	RNA recognition motif
PCNPT3_RS09480	COG0717	Belongs to the dCTP deaminase family
PCNPT3_RS09485	COG1278	Cold shock
PCNPT3_RS09490	COG1671	Belongs to the UPF0178 family
PCNPT3_RS09500	COG1477	protein flavinylation
PCNPT3_RS09505	COG2871	sodium ion transport
PCNPT3_RS09510	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PCNPT3_RS09515	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PCNPT3_RS09525	COG1805	sodium ion transport
PCNPT3_RS09530	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PCNPT3_RS09535	COG0271	Belongs to the BolA IbaG family
PCNPT3_RS09540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PCNPT3_RS09545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PCNPT3_RS09550	COG0542	response to heat
PCNPT3_RS09555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PCNPT3_RS09560	COG0784	Response regulator, receiver
PCNPT3_RS09560	COG0835	chemotaxis
PCNPT3_RS09565	COG0602	queuosine metabolic process
PCNPT3_RS09570	COG1328	CTP reductase activity
PCNPT3_RS09575	COG4657	Part of a membrane complex involved in electron transport
PCNPT3_RS09590	COG4658	electron transport chain
PCNPT3_RS09595	COG4659	FMN binding
PCNPT3_RS09600	COG4660	Part of a membrane complex involved in electron transport
PCNPT3_RS09605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCNPT3_RS09615	COG0210	DNA helicase
PCNPT3_RS09620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCNPT3_RS09635	COG4807	Protein conserved in bacteria
PCNPT3_RS09650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PCNPT3_RS09690	COG2885	chlorophyll binding
PCNPT3_RS09695	COG0823	Involved in the tonB-independent uptake of proteins
PCNPT3_RS09705	COG0848	biopolymer transport protein
PCNPT3_RS09710	COG0811	peptide transport
PCNPT3_RS09715	COG0824	Thioesterase
PCNPT3_RS09720	COG3790	cyd operon protein YbgE
PCNPT3_RS09730	COG1294	oxidase, subunit
PCNPT3_RS09745	COG2255	four-way junction helicase activity
PCNPT3_RS09750	COG0632	four-way junction helicase activity
PCNPT3_RS09755	COG2962	Rard protein
PCNPT3_RS09760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PCNPT3_RS09765	COG0583	DNA-binding transcription factor activity
PCNPT3_RS09770	COG0288	reversible hydration of carbon dioxide
PCNPT3_RS09780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PCNPT3_RS09785	COG2226	methyltransferase
PCNPT3_RS09790	COG0500	methyltransferase
PCNPT3_RS09815	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PCNPT3_RS09820	COG1132	(ABC) transporter
PCNPT3_RS09825	COG2067	long-chain fatty acid transport protein
PCNPT3_RS09830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCNPT3_RS09835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCNPT3_RS09855	COG0564	pseudouridine synthase activity
PCNPT3_RS09880	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PCNPT3_RS09900	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PCNPT3_RS09900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PCNPT3_RS09920	COG1611	Belongs to the LOG family
PCNPT3_RS09925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCNPT3_RS09930	COG2252	PERMEase
PCNPT3_RS09935	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PCNPT3_RS09940	COG1757	Na H antiporter
PCNPT3_RS09960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCNPT3_RS09965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PCNPT3_RS09970	COG1702	phosphate starvation-inducible protein PhoH
PCNPT3_RS09975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PCNPT3_RS09985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PCNPT3_RS09990	COG4067	protein conserved in archaea
PCNPT3_RS09990	COG0189	ligase activity
PCNPT3_RS10010	COG2969	positive regulation of protein catabolic process
PCNPT3_RS10015	COG0625	glutathione transferase activity
PCNPT3_RS10020	COG2857	Cytochrome c1
PCNPT3_RS10025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PCNPT3_RS10030	COG0723	plastoquinol--plastocyanin reductase activity
PCNPT3_RS10035	COG1528	Iron-storage protein
PCNPT3_RS10045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PCNPT3_RS10050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PCNPT3_RS10055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PCNPT3_RS10065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCNPT3_RS10070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCNPT3_RS10075	COG5007	Belongs to the BolA IbaG family
PCNPT3_RS10085	COG2854	intermembrane phospholipid transfer
PCNPT3_RS10090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PCNPT3_RS10095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PCNPT3_RS10100	COG1127	ABC transporter
PCNPT3_RS10105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PCNPT3_RS10115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PCNPT3_RS10120	COG1137	ATPase activity
PCNPT3_RS10125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PCNPT3_RS10130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCNPT3_RS10135	COG1660	Displays ATPase and GTPase activities
PCNPT3_RS10140	COG2239	Acts as a magnesium transporter
PCNPT3_RS10165	COG1522	sequence-specific DNA binding
PCNPT3_RS10170	COG0482	sulfurtransferase activity
PCNPT3_RS10180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCNPT3_RS10185	COG2084	Dehydrogenase
PCNPT3_RS10195	COG2850	peptidyl-arginine hydroxylation
PCNPT3_RS10200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCNPT3_RS10205	COG0583	DNA-binding transcription factor activity
PCNPT3_RS10210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCNPT3_RS10220	COG2188	Transcriptional regulator
PCNPT3_RS10230	COG3842	ATPase activity
PCNPT3_RS10235	COG1840	ABC-type Fe3 transport system, periplasmic component
PCNPT3_RS10240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PCNPT3_RS10245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCNPT3_RS10250	COG0563	adenylate kinase activity
PCNPT3_RS10255	COG0326	Molecular chaperone. Has ATPase activity
PCNPT3_RS10260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PCNPT3_RS10300	COG0564	pseudouridine synthase activity
PCNPT3_RS10305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PCNPT3_RS10310	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PCNPT3_RS10330	COG0459	protein refolding
PCNPT3_RS10345	COG3030	protein affecting phage T7 exclusion by the F plasmid
PCNPT3_RS10350	COG2814	Major facilitator Superfamily
PCNPT3_RS10365	COG2194	sulfuric ester hydrolase activity
PCNPT3_RS10370	COG0745	RESPONSE REGULATOR receiver
PCNPT3_RS10375	COG5002	protein histidine kinase activity
PCNPT3_RS10380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PCNPT3_RS10395	COG1238	metal cluster binding
PCNPT3_RS10400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PCNPT3_RS10405	COG0585	pseudouridine synthase activity
PCNPT3_RS10415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PCNPT3_RS10420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PCNPT3_RS10445	COG0672	)-iron permease
PCNPT3_RS10465	COG0148	phosphopyruvate hydratase activity
PCNPT3_RS10470	COG0504	CTP synthase activity
PCNPT3_RS10475	COG3023	N-Acetylmuramoyl-L-alanine amidase
PCNPT3_RS10480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PCNPT3_RS10480	COG0519	Catalyzes the synthesis of GMP from XMP
PCNPT3_RS10485	COG0517	IMP dehydrogenase activity
PCNPT3_RS10485	COG0516	GMP reductase activity
PCNPT3_RS10495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PCNPT3_RS10500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PCNPT3_RS10510	COG1073	alpha beta
PCNPT3_RS10530	COG0037	tRNA processing
PCNPT3_RS10535	COG0587	DNA-directed DNA polymerase activity
PCNPT3_RS10540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCNPT3_RS10545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCNPT3_RS10550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCNPT3_RS10555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PCNPT3_RS10560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCNPT3_RS10570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCNPT3_RS10575	COG0750	zinc metalloprotease
PCNPT3_RS10580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PCNPT3_RS10585	COG0575	Belongs to the CDS family
PCNPT3_RS10590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCNPT3_RS10595	COG0233	cytoplasmic translational termination
PCNPT3_RS10600	COG0528	UMP kinase activity
PCNPT3_RS10605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PCNPT3_RS10610	COG0052	Belongs to the universal ribosomal protein uS2 family
PCNPT3_RS10625	COG3842	ATPase activity
PCNPT3_RS10635	COG1840	ABC-type Fe3 transport system, periplasmic component
PCNPT3_RS10685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCNPT3_RS10690	COG3716	PTS system mannose fructose sorbose family IID component
PCNPT3_RS10695	COG3715	PTS system
PCNPT3_RS10700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCNPT3_RS10705	COG2222	sugar isomerase
PCNPT3_RS10730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PCNPT3_RS10750	COG0284	orotidine-5'-phosphate decarboxylase activity
PCNPT3_RS10755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PCNPT3_RS10765	COG0776	regulation of translation
PCNPT3_RS10770	COG0539	negative regulation of cytoplasmic translation
PCNPT3_RS10775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PCNPT3_RS10795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCNPT3_RS10800	COG1138	Cytochrome C-type biogenesis protein
PCNPT3_RS10805	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PCNPT3_RS10810	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCNPT3_RS10815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCNPT3_RS10820	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCNPT3_RS10825	COG4133	protoheme IX ABC transporter activity
PCNPT3_RS10835	COG0835	chemotaxis
PCNPT3_RS10845	COG1192	Involved in chromosome partitioning
PCNPT3_RS10850	COG1360	Flagellar Motor Protein
PCNPT3_RS10855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PCNPT3_RS10860	COG2201	protein-glutamate methylesterase activity
PCNPT3_RS10865	COG2198	Histidine kinase
PCNPT3_RS10865	COG0643	Histidine kinase
PCNPT3_RS10865	COG0784	Response regulator, receiver
PCNPT3_RS10870	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PCNPT3_RS10905	COG1684	flagellar biosynthetic protein fliR
PCNPT3_RS10910	COG1987	bacterial-type flagellum assembly
PCNPT3_RS10960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PCNPT3_RS10970	COG1677	Flagellar hook-basal body complex protein FliE
PCNPT3_RS10985	COG0004	ammonium transporteR
PCNPT3_RS10995	COG1686	Belongs to the peptidase S11 family
PCNPT3_RS11000	COG2921	Belongs to the UPF0250 family
PCNPT3_RS11005	COG0321	lipoyl(octanoyl) transferase activity
PCNPT3_RS11010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PCNPT3_RS11020	COG2200	EAL domain
PCNPT3_RS11020	COG2199	diguanylate cyclase activity
PCNPT3_RS11025	COG2813	Specifically methylates the guanine in position
PCNPT3_RS11035	COG0840	transmembrane signaling receptor activity
PCNPT3_RS11040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PCNPT3_RS11040	COG0517	IMP dehydrogenase activity
PCNPT3_RS11080	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PCNPT3_RS11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCNPT3_RS11090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCNPT3_RS11095	COG0006	proline dipeptidase activity
PCNPT3_RS11100	COG3079	Belongs to the UPF0149 family
PCNPT3_RS11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCNPT3_RS11135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCNPT3_RS11140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PCNPT3_RS11145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PCNPT3_RS11150	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PCNPT3_RS11155	COG2166	iron-sulfur cluster assembly
PCNPT3_RS11160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PCNPT3_RS11165	COG1643	Atp-dependent helicase
PCNPT3_RS11175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCNPT3_RS11180	COG0617	tRNA 3'-terminal CCA addition
PCNPT3_RS11185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PCNPT3_RS11190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PCNPT3_RS11195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PCNPT3_RS11200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PCNPT3_RS11225	COG0346	lactoylglutathione lyase activity
PCNPT3_RS11235	COG2390	Transcriptional regulator
PCNPT3_RS11250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PCNPT3_RS11255	COG0842	Transport permease protein
PCNPT3_RS11260	COG1131	(ABC) transporter
PCNPT3_RS11290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PCNPT3_RS11295	COG0163	prenyltransferase activity
PCNPT3_RS11300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PCNPT3_RS11305	COG1227	inorganic diphosphatase activity
PCNPT3_RS11315	COG1929	Belongs to the glycerate kinase type-1 family
PCNPT3_RS11320	COG0742	ribosomal rna small subunit methyltransferase
PCNPT3_RS11325	COG0439	Biotin carboxylase
PCNPT3_RS11330	COG0281	malic enzyme
PCNPT3_RS11335	COG0254	rRNA binding
PCNPT3_RS11350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PCNPT3_RS11355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PCNPT3_RS11360	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PCNPT3_RS11365	COG0813	purine-nucleoside phosphorylase activity
PCNPT3_RS11375	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PCNPT3_RS11385	COG0295	cytidine deaminase activity
PCNPT3_RS11395	COG2356	endonuclease I
PCNPT3_RS11400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCNPT3_RS11405	COG5001	Diguanylate cyclase
PCNPT3_RS11405	COG4251	negative regulation of phosphorylation
PCNPT3_RS11405	COG3706	GGDEF domain
PCNPT3_RS11405	COG2203	Gaf domain
PCNPT3_RS11415	COG1115	amino acid carrier protein
PCNPT3_RS11420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PCNPT3_RS11425	COG1194	a g-specific adenine glycosylase
PCNPT3_RS11430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PCNPT3_RS11465	COG0191	fructose-bisphosphate aldolase activity
PCNPT3_RS11470	COG0126	phosphoglycerate kinase activity
PCNPT3_RS11475	COG4251	negative regulation of phosphorylation
PCNPT3_RS11475	COG5001	Diguanylate cyclase
PCNPT3_RS11475	COG2203	Gaf domain
PCNPT3_RS11475	COG3706	GGDEF domain
PCNPT3_RS11485	COG1129	ABC transporter
PCNPT3_RS11495	COG1609	Transcriptional regulator
PCNPT3_RS11500	COG1388	LysM domain
PCNPT3_RS11500	COG0741	lytic transglycosylase activity
PCNPT3_RS11505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PCNPT3_RS11510	COG2226	methyltransferase
PCNPT3_RS11515	COG0328	RNA-DNA hybrid ribonuclease activity
PCNPT3_RS11520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCNPT3_RS11560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCNPT3_RS11580	COG0363	glucosamine-6-phosphate deaminase activity
PCNPT3_RS11585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCNPT3_RS11590	COG1846	Transcriptional regulator
PCNPT3_RS11590	COG1940	carbohydrate kinase activity
PCNPT3_RS11595	COG1459	type II secretion system
PCNPT3_RS11600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCNPT3_RS11610	COG0735	belongs to the Fur family
PCNPT3_RS11635	COG0488	(ABC) transporter
PCNPT3_RS11645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCNPT3_RS11650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PCNPT3_RS11655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCNPT3_RS11660	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PCNPT3_RS11665	COG0494	nUDIX hydrolase
PCNPT3_RS11675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PCNPT3_RS11685	COG0741	lytic transglycosylase activity
PCNPT3_RS11710	COG2022	thiamine diphosphate biosynthetic process
PCNPT3_RS11720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PCNPT3_RS11730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PCNPT3_RS11735	COG2991	Protein conserved in bacteria
PCNPT3_RS11745	COG1342	Belongs to the UPF0251 family
PCNPT3_RS11760	COG1230	cation diffusion facilitator family transporter
PCNPT3_RS11765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCNPT3_RS11770	COG1575	Belongs to the MenA family. Type 1 subfamily
PCNPT3_RS11775	COG1169	isochorismate synthase
PCNPT3_RS11780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PCNPT3_RS11790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PCNPT3_RS11795	COG0450	alkyl hydroperoxide reductase
PCNPT3_RS11805	COG3089	Belongs to the UPF0270 family
PCNPT3_RS11825	COG3240	lipase activity
PCNPT3_RS11850	COG0488	(ABC) transporter
PCNPT3_RS11855	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PCNPT3_RS11860	COG1047	Peptidyl-prolyl cis-trans
PCNPT3_RS11885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PCNPT3_RS11885	COG0316	Belongs to the HesB IscA family
PCNPT3_RS11890	COG0513	Belongs to the DEAD box helicase family
PCNPT3_RS11895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PCNPT3_RS11900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PCNPT3_RS11905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCNPT3_RS11910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PCNPT3_RS11915	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PCNPT3_RS11925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCNPT3_RS11930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCNPT3_RS12010	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PCNPT3_RS12045	COG0583	DNA-binding transcription factor activity
PCNPT3_RS12050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PCNPT3_RS12055	COG2814	Major facilitator Superfamily
PCNPT3_RS12060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PCNPT3_RS12065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PCNPT3_RS12075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PCNPT3_RS12090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PCNPT3_RS12095	COG2814	Major facilitator Superfamily
PCNPT3_RS12105	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PCNPT3_RS12110	COG1011	Hydrolase
PCNPT3_RS12115	COG0733	neurotransmitter:sodium symporter activity
PCNPT3_RS12120	COG1522	sequence-specific DNA binding
PCNPT3_RS12130	COG0784	Response regulator, receiver
PCNPT3_RS12130	COG3437	response regulator, receiver
PCNPT3_RS12135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PCNPT3_RS12145	COG1215	transferase activity, transferring glycosyl groups
PCNPT3_RS12205	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PCNPT3_RS12210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PCNPT3_RS12215	COG0705	Rhomboid family
PCNPT3_RS12220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCNPT3_RS12225	COG4137	Cytochrome C assembly protein
PCNPT3_RS12230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCNPT3_RS12235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCNPT3_RS12240	COG4536	flavin adenine dinucleotide binding
PCNPT3_RS12250	COG2918	glutathione biosynthetic process
PCNPT3_RS12275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PCNPT3_RS12285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PCNPT3_RS12315	COG0252	asparaginase activity
PCNPT3_RS12320	COG0514	ATP-dependent DNA helicase (RecQ)
PCNPT3_RS12325	COG3148	PFAM DTW domain containing protein
PCNPT3_RS12335	COG1763	Mo-molybdopterin cofactor biosynthetic process
PCNPT3_RS12340	COG1280	lysine exporter protein (LysE YggA)
PCNPT3_RS12345	COG4989	oxidoreductase activity
PCNPT3_RS12365	COG0557	exoribonuclease II activity
PCNPT3_RS12370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCNPT3_RS12380	COG0360	Binds together with S18 to 16S ribosomal RNA
PCNPT3_RS12385	COG2965	DNA replication, synthesis of RNA primer
PCNPT3_RS12390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCNPT3_RS12410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCNPT3_RS12425	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCNPT3_RS12430	COG1349	DNA-binding transcription factor activity
PCNPT3_RS12435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PCNPT3_RS12455	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PCNPT3_RS12475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PCNPT3_RS12480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCNPT3_RS12485	COG0049	tRNA binding
PCNPT3_RS12490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PCNPT3_RS12500	COG2923	Belongs to the DsrF TusC family
PCNPT3_RS12505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PCNPT3_RS12510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCNPT3_RS12515	COG0085	RNA polymerase activity
PCNPT3_RS12520	COG0222	ribosome binding
PCNPT3_RS12525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PCNPT3_RS12530	COG0081	regulation of translation
PCNPT3_RS12535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PCNPT3_RS12545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PCNPT3_RS12550	COG0612	Peptidase, M16
PCNPT3_RS12560	COG4178	(ABC) transporter
PCNPT3_RS12565	COG4771	TonB-dependent receptor
PCNPT3_RS12575	COG0811	peptide transport
PCNPT3_RS12585	COG0848	biopolymer transport protein
PCNPT3_RS12600	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PCNPT3_RS12610	COG0840	transmembrane signaling receptor activity
PCNPT3_RS12625	COG1136	(ABC) transporter
PCNPT3_RS12650	COG1136	(ABC) transporter
PCNPT3_RS12650	COG0577	efflux transmembrane transporter activity
PCNPT3_RS12660	COG0577	efflux transmembrane transporter activity
PCNPT3_RS12660	COG1136	(ABC) transporter
PCNPT3_RS12675	COG0672	)-iron permease
PCNPT3_RS12680	COG0786	glutamate:sodium symporter activity
PCNPT3_RS12690	COG0463	Glycosyl transferase, family 2
PCNPT3_RS12695	COG0251	oxidation-reduction process
PCNPT3_RS12710	COG1921	L-seryl-tRNASec selenium transferase activity
PCNPT3_RS12720	COG2897	thiosulfate sulfurtransferase activity
PCNPT3_RS12735	COG3383	formate dehydrogenase (NAD+) activity
PCNPT3_RS12740	COG3383	formate dehydrogenase (NAD+) activity
PCNPT3_RS12745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCNPT3_RS12750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PCNPT3_RS12760	COG3260	NADH ubiquinone oxidoreductase 20
PCNPT3_RS12765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCNPT3_RS12770	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PCNPT3_RS12770	COG3261	NADH dehydrogenase
PCNPT3_RS12775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCNPT3_RS12780	COG0650	Formate hydrogenlyase subunit 4
PCNPT3_RS12785	COG0651	ATP synthesis coupled electron transport
PCNPT3_RS12790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCNPT3_RS12795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PCNPT3_RS12810	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PCNPT3_RS12815	COG0298	carbon dioxide binding
PCNPT3_RS12820	COG0409	Hydrogenase expression formation protein
PCNPT3_RS12825	COG0309	Hydrogenase expression formation protein (HypE)
PCNPT3_RS12845	COG2376	Dihydroxyacetone kinase
PCNPT3_RS12850	COG1461	Dihydroxyacetone kinase
PCNPT3_RS12865	COG3284	Transcriptional regulator
PCNPT3_RS12870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCNPT3_RS12880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCNPT3_RS12890	COG1280	lysine exporter protein (LysE YggA)
PCNPT3_RS12895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PCNPT3_RS12925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PCNPT3_RS12935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCNPT3_RS12940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PCNPT3_RS12950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PCNPT3_RS12960	COG0339	signal peptide processing
PCNPT3_RS12965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCNPT3_RS12965	COG4191	Histidine kinase
PCNPT3_RS12970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PCNPT3_RS12980	COG3078	GTPase activator activity
PCNPT3_RS12990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCNPT3_RS12995	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PCNPT3_RS13005	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PCNPT3_RS13010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCNPT3_RS13020	COG3593	DNA synthesis involved in DNA repair
PCNPT3_RS13030	COG3706	GGDEF domain
PCNPT3_RS13035	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
PCNPT3_RS13040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCNPT3_RS13045	COG1739	Uncharacterized protein family UPF0029
PCNPT3_RS13055	COG0305	Participates in initiation and elongation during chromosome replication
PCNPT3_RS13060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCNPT3_RS13070	COG0318	PFAM AMP-dependent synthetase and ligase
PCNPT3_RS13075	COG1560	Kdo2-lipid A biosynthetic process
PCNPT3_RS13080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PCNPT3_RS13085	COG3789	protein conserved in bacteria
PCNPT3_RS13115	COG1392	Phosphate transport regulator
PCNPT3_RS13120	COG0306	phosphate transporter
PCNPT3_RS13140	COG3267	Type II secretory pathway component ExeA
PCNPT3_RS13140	COG3409	Peptidoglycan-binding domain 1 protein
PCNPT3_RS13145	COG0617	tRNA 3'-terminal CCA addition
PCNPT3_RS13150	COG1968	undecaprenyl-diphosphatase activity
PCNPT3_RS13155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PCNPT3_RS13155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PCNPT3_RS13160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCNPT3_RS13165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PCNPT3_RS13175	COG0346	lactoylglutathione lyase activity
PCNPT3_RS13180	COG2731	YhcH YjgK YiaL family protein
PCNPT3_RS13185	COG1940	carbohydrate kinase activity
PCNPT3_RS13190	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PCNPT3_RS13195	COG1737	Transcriptional regulator
PCNPT3_RS13200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCNPT3_RS13205	COG0180	Tryptophanyl-tRNA synthetase
PCNPT3_RS13210	COG0546	phosphoglycolate phosphatase activity
PCNPT3_RS13215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PCNPT3_RS13220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PCNPT3_RS13230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PCNPT3_RS13235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PCNPT3_RS13265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PCNPT3_RS13270	COG1011	Hydrolase
PCNPT3_RS13275	COG0494	nUDIX hydrolase
PCNPT3_RS13280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCNPT3_RS13290	COG3217	Mosc domain protein beta barrel domain protein
PCNPT3_RS13290	COG0633	Ferredoxin
PCNPT3_RS13320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PCNPT3_RS13325	COG1561	YicC-like family, N-terminal region
PCNPT3_RS13355	COG0463	Glycosyl transferase, family 2
PCNPT3_RS13375	COG0840	transmembrane signaling receptor activity
PCNPT3_RS13385	COG3655	Transcriptional regulator
PCNPT3_RS13395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PCNPT3_RS13400	COG3084	Protein conserved in bacteria
PCNPT3_RS13410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PCNPT3_RS13415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PCNPT3_RS13425	COG1072	(Pantothenic acid kinase))
PCNPT3_RS13430	COG1494	fructose-1,6-bisphosphatase
PCNPT3_RS13440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCNPT3_RS13445	COG0706	membrane insertase activity
PCNPT3_RS13450	COG0594	ribonuclease P activity
PCNPT3_RS13455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PCNPT3_RS13470	COG2226	methyltransferase
PCNPT3_RS13475	COG1309	transcriptional regulator
PCNPT3_RS13490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCNPT3_RS13490	COG4191	Histidine kinase
PCNPT3_RS13520	COG4932	domain protein
PCNPT3_RS13520	COG5492	domain, Protein
PCNPT3_RS13535	COG3547	Transposase (IS116 IS110 IS902 family)
PCNPT3_RS13560	COG0076	glutamate decarboxylase activity
PCNPT3_RS13605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCNPT3_RS13615	COG0811	peptide transport