locus-tag	class	description
HG718_RS00035	ENOG4105EY8	ABC transporter
HG718_RS00045	ENOG4105CAQ	asparagine synthetase
HG718_RS00050	ENOG4105CMR	udp-glucose 4-epimerase
HG718_RS00055	ENOG4105CMR	udp-glucose 4-epimerase
HG718_RS00060	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HG718_RS00065	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HG718_RS00080	ENOG4107QQG	Dehydrogenase
HG718_RS00085	ENOG4107R5Z	Oxidoreductase domain protein
HG718_RS00090	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HG718_RS00095	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HG718_RS00105	ENOG4105CAQ	asparagine synthetase
HG718_RS00115	ENOG41082R8	50S ribosomal protein l32
HG718_RS00125	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
HG718_RS00130	ENOG4105DDQ	anthranilate synthase
HG718_RS00140	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HG718_RS00155	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG718_RS00160	ENOG4105BZU	Histidine kinase
HG718_RS00165	ENOG4108NVM	synthesis repressor PhaR
HG718_RS00175	ENOG4108ZJ4	polysaccharide deacetylase
HG718_RS00185	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HG718_RS00195	ENOG4108YZA	Nitrogen regulatory protein pii
HG718_RS00205	ENOG4105DWV	Homoserine O-trans-acetylase
HG718_RS00215	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG718_RS00250	ENOG4105CAK	Cell division ATP-binding protein ftsE
HG718_RS00275	ENOG4105CH7	arginosuccinase
HG718_RS00280	ENOG4107ZT5	Thiol disulfide interchange protein
HG718_RS00290	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG718_RS00295	ENOG4105C10	Electron transfer flavoprotein
HG718_RS00300	ENOG4105BZJ	Electron transfer flavoprotein
HG718_RS00310	ENOG4105VMP	Transcriptional regulator
HG718_RS00320	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
HG718_RS00340	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS00370	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HG718_RS00380	ENOG4106CJB	Phospholipase Carboxylesterase
HG718_RS00395	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HG718_RS00645	ENOG4105BZ1	(ABC) transporter
HG718_RS00670	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HG718_RS00675	ENOG4105CEY	Amp-dependent synthetase and ligase
HG718_RS00700	ENOG4108Z7R	Chaperone CsaA
HG718_RS00730	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HG718_RS00750	ENOG4105CQB	FAD linked oxidase domain protein
HG718_RS00780	ENOG4105CHR	reductase
HG718_RS00785	ENOG4105CSU	acyl-Coa dehydrogenase
HG718_RS00805	ENOG4105C09	Bile acid
HG718_RS00815	ENOG4108W8B	Beta-lactamase domain protein
HG718_RS00850	ENOG4105ERG	peptidase m48, ste24p
HG718_RS00855	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG718_RS00865	ENOG4108Z4U	Ferredoxin
HG718_RS00880	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS00885	ENOG4105BZU	Histidine kinase
HG718_RS00905	ENOG4105KDC	50s ribosomal protein l28
HG718_RS00940	ENOG4108JU6	CBS domain protein
HG718_RS00945	ENOG4105D49	3-dehydroquinate synthase
HG718_RS00950	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HG718_RS00965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG718_RS00975	ENOG4108KPJ	rna polymerase sigma factor
HG718_RS00985	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HG718_RS00990	ENOG4105CIR	epoxide hydrolase
HG718_RS00995	ENOG4105CIR	epoxide hydrolase
HG718_RS01010	ENOG4105DNH	Major Facilitator
HG718_RS01015	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HG718_RS01020	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HG718_RS01025	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HG718_RS01030	ENOG4105M6F	mutator MutT protein
HG718_RS01040	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HG718_RS01045	ENOG4105MJ2	Competence protein
HG718_RS01050	ENOG4105VW4	glutaredoxin 3
HG718_RS01065	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HG718_RS01070	ENOG4105CFH	Aspartokinase
HG718_RS01075	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HG718_RS01085	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HG718_RS01090	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HG718_RS01105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG718_RS01115	ENOG4105DR5	peptidase
HG718_RS01150	ENOG4107Y03	Nitroreductase
HG718_RS01155	ENOG4105CC0	LysR family Transcriptional regulator
HG718_RS01165	ENOG4108RYK	Nad-dependent epimerase dehydratase
HG718_RS01170	ENOG4105CHH	sulfate transporter
HG718_RS01205	ENOG4105CHR	reductase
HG718_RS01225	ENOG4105CAQ	asparagine synthetase
HG718_RS01230	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HG718_RS01235	ENOG4105K64	Glycosyl transferase, family 2
HG718_RS01260	ENOG4105E0K	tonB-dependent siderophore receptor
HG718_RS01305	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HG718_RS01315	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HG718_RS01345	ENOG4105D5U	fad dependent oxidoreductase
HG718_RS01350	ENOG4105D3Q	Sugar transferase
HG718_RS01365	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HG718_RS01375	ENOG4105CVE	Lytic murein transglycosylase
HG718_RS01385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG718_RS01390	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HG718_RS01405	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HG718_RS01430	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HG718_RS01455	ENOG4105E18	UPF0276 protein
HG718_RS01470	ENOG4105C5W	Aldolase
HG718_RS01475	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HG718_RS01490	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HG718_RS01495	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HG718_RS01505	ENOG4105C59	p-type ATPase
HG718_RS01520	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG718_RS01540	ENOG4108ZNX	Heat shock protein
HG718_RS01550	ENOG4105H1G	trap transporter solute receptor taxi family
HG718_RS01565	ENOG4107QX3	carboxylase
HG718_RS01580	ENOG4105CI3	gtp-binding protein typa
HG718_RS01585	ENOG4108YYC	ycei family
HG718_RS01590	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG718_RS01600	ENOG4105CBD	Diacylglycerol kinase
HG718_RS01605	ENOG4105CBC	glutamate synthase
HG718_RS01635	ENOG4108JJA	ABC, transporter
HG718_RS01640	ENOG4108JJA	ABC, transporter
HG718_RS01645	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HG718_RS01650	ENOG4108RXX	maleylacetoacetate isomerase
HG718_RS01655	ENOG41089UC	methyltransferase, type 11
HG718_RS01680	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS01690	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HG718_RS01695	ENOG4105CHR	reductase
HG718_RS01700	ENOG4107RDB	Major Facilitator
HG718_RS01710	ENOG4105YK5	50S ribosomal protein L36
HG718_RS01715	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG718_RS01720	ENOG4105EG6	Saccharopine dehydrogenase
HG718_RS01730	ENOG4108J2P	Alpha beta hydrolase fold
HG718_RS01735	ENOG4105CA9	Pyruvate kinase
HG718_RS01750	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HG718_RS01760	ENOG4105Y2X	UPF0335 protein
HG718_RS01765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG718_RS01770	ENOG4105CDV	Ompa motb domain protein
HG718_RS01795	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG718_RS01800	ENOG4105W8H	transhydrogenase (subunit alpha
HG718_RS01805	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG718_RS01810	ENOG4105K5G	30S ribosomal protein S21
HG718_RS01815	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HG718_RS01830	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HG718_RS01835	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HG718_RS01840	ENOG4105BZU	Histidine kinase
HG718_RS01860	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
HG718_RS01870	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG718_RS01875	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HG718_RS01900	ENOG41082FS	50S ribosomal protein L31
HG718_RS01905	ENOG4105BZ1	(ABC) transporter
HG718_RS01945	ENOG4105ECY	inositol monophosphatase
HG718_RS01950	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HG718_RS01960	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HG718_RS01965	ENOG4107R1Y	fructose-bisphosphate aldolase
HG718_RS01970	ENOG4105BZA	Phosphoglycerate kinase
HG718_RS02000	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HG718_RS02005	ENOG4105D48	metallophosphoesterase
HG718_RS02010	ENOG4105CDY	transcriptional regulatory protein
HG718_RS02015	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HG718_RS02020	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HG718_RS02025	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HG718_RS02030	ENOG4107YD3	Thioesterase
HG718_RS02035	ENOG4105E02	MotA TolQ exbB proton channel
HG718_RS02040	ENOG4108ZZF	transport protein (ExbD)
HG718_RS02050	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HG718_RS02055	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HG718_RS02065	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HG718_RS02070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG718_RS02080	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HG718_RS02085	ENOG4105DWF	phosphomethylpyrimidine kinase
HG718_RS02090	ENOG4107SQD	Transcriptional regulator, GntR family
HG718_RS02095	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HG718_RS02105	ENOG4105FDR	Membrane
HG718_RS02120	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HG718_RS02130	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HG718_RS02145	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HG718_RS02165	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HG718_RS02225	ENOG410689M	(LipO)protein
HG718_RS02235	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HG718_RS02240	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HG718_RS02250	ENOG4105CBS	Chea signal transduction histidine kinase
HG718_RS02255	ENOG4108ZGA	chew protein
HG718_RS02265	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HG718_RS02270	ENOG4105BZU	Histidine kinase
HG718_RS02275	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
HG718_RS02300	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HG718_RS02305	ENOG4105D7B	Flagellar biosynthesis protein flha
HG718_RS02310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG718_RS02315	ENOG4105E14	MotA TolQ exbB proton channel
HG718_RS02320	ENOG4105DD5	Flagellar motor switch protein
HG718_RS02325	ENOG4106FNV	Flagellar assembly protein
HG718_RS02330	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HG718_RS02335	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HG718_RS02345	ENOG410822I	Flagellar hook capping protein
HG718_RS02355	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HG718_RS02375	ENOG4105CY0	Metallo-Beta-Lactamase
HG718_RS02410	ENOG4105D3G	Pseudouridine synthase
HG718_RS02425	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS02435	ENOG4108J2P	Alpha beta hydrolase fold
HG718_RS02440	ENOG4108UQY	Iron-storage protein
HG718_RS02465	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HG718_RS02475	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HG718_RS02480	ENOG4105F95	Monooxygenase
HG718_RS02500	ENOG4105CFF	transcriptional regulator
HG718_RS02505	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS02510	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS02525	ENOG4105C5I	Dehydrogenase
HG718_RS02565	ENOG4105FGF	GDP-mannose mannosyl hydrolase
HG718_RS02585	ENOG4105C2I	pirin domain protein
HG718_RS02595	ENOG4105CHR	reductase
HG718_RS02620	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG718_RS02630	ENOG4105P8F	nudix hydrolase
HG718_RS02645	ENOG4105BZU	Histidine kinase
HG718_RS02655	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HG718_RS02660	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HG718_RS02665	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG718_RS02670	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG718_RS02675	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG718_RS02680	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HG718_RS02685	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HG718_RS02690	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HG718_RS02715	ENOG4105C3G	gtp-binding protein
HG718_RS02720	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HG718_RS02725	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HG718_RS02735	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HG718_RS02745	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HG718_RS02755	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HG718_RS02770	ENOG4105II7	pyrroline-5-carboxylate reductase
HG718_RS02780	ENOG4105E0F	Histidine kinase
HG718_RS02785	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HG718_RS02790	ENOG41090HR	transcriptional regulator
HG718_RS02800	ENOG4108ZAF	Molybdopterin
HG718_RS02805	ENOG4105M00	molybdopterin converting factor, subunit 1
HG718_RS02825	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HG718_RS02855	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HG718_RS02860	ENOG4107STQ	Multicopper oxidase
HG718_RS02870	ENOG4105UT3	Methyl-accepting chemotaxis
HG718_RS02910	ENOG4108RXX	maleylacetoacetate isomerase
HG718_RS02945	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HG718_RS02960	ENOG4105ETT	transcriptional Regulator, LysR family
HG718_RS02965	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HG718_RS02970	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HG718_RS02980	ENOG4105D3R	alkyl hydroperoxide reductase
HG718_RS02990	ENOG4105F7P	transcriptional regulator AsnC family
HG718_RS02995	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HG718_RS03000	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HG718_RS03005	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HG718_RS03015	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HG718_RS03025	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HG718_RS03030	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG718_RS03045	ENOG4107E2E	PKHD-type hydroxylase
HG718_RS03090	ENOG4105MPN	Membrane
HG718_RS03125	ENOG4107XI7	Tetr family transcriptional regulator
HG718_RS03130	ENOG4105C5H	ABC transporter
HG718_RS03135	ENOG4105EIE	fructose-bisphosphate aldolase
HG718_RS03150	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG718_RS03155	ENOG4105SYT	Methylenetetrahydrofolate reductase
HG718_RS03165	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HG718_RS03180	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HG718_RS03195	ENOG4107YUR	Cell division protein mraZ
HG718_RS03200	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HG718_RS03215	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HG718_RS03225	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HG718_RS03230	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HG718_RS03240	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HG718_RS03245	ENOG4105DFU	Cell wall formation (By similarity)
HG718_RS03250	ENOG4105D4A	Cell wall formation (By similarity)
HG718_RS03255	ENOG4105CPF	Cell wall formation (By similarity)
HG718_RS03265	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HG718_RS03270	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HG718_RS03280	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG718_RS03285	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG718_RS03290	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HG718_RS03295	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HG718_RS03300	ENOG4105DC7	peptidase M24
HG718_RS03300	ENOG4105DC7	peptidase M24
HG718_RS03305	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG718_RS03310	ENOG4105C4R	Atp-dependent dna helicase
HG718_RS03315	ENOG4105CMQ	Chloride channel
HG718_RS03335	ENOG4105CQB	FAD linked oxidase domain protein
HG718_RS03355	ENOG4105C9Q	fumarate hydratase class II
HG718_RS03370	ENOG4108IGT	Dipeptidase
HG718_RS03410	ENOG4107QJR	hflk protein
HG718_RS03430	ENOG4105EAC	phosphoserine phosphatase
HG718_RS03435	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HG718_RS03440	ENOG4105C7K	acetolactate synthase
HG718_RS03450	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HG718_RS03475	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HG718_RS03505	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HG718_RS03515	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HG718_RS03525	ENOG4105CJN	penicillin-binding protein
HG718_RS03530	ENOG4105CNI	cell division protein FtsW
HG718_RS03550	ENOG4105BZU	Histidine kinase
HG718_RS03575	ENOG4108TF4	von Willebrand factor, type A
HG718_RS03580	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HG718_RS03585	ENOG4105Q9Y	Universal stress protein
HG718_RS03590	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG718_RS03610	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HG718_RS03615	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HG718_RS03620	ENOG4108WBT	adenosyltransferase
HG718_RS03625	ENOG4105C3R	Methionine synthase
HG718_RS03635	ENOG4105EV8	ectoine hydroxylase
HG718_RS03660	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG718_RS03665	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG718_RS03680	ENOG4105D74	hydrolase
HG718_RS03690	ENOG4105CEY	Amp-dependent synthetase and ligase
HG718_RS03720	ENOG4105G9V	cytochrome C
HG718_RS03725	ENOG4105CY3	ABC transporter, permease
HG718_RS03730	ENOG4105DHJ	ABC, transporter
HG718_RS03735	ENOG4108SNX	Mammalian cell entry related domain protein
HG718_RS03760	ENOG4108RZE	Tetr family transcriptional regulator
HG718_RS03770	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HG718_RS03775	ENOG4105CMR	udp-glucose 4-epimerase
HG718_RS03780	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HG718_RS03785	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HG718_RS03790	ENOG4105D2T	synthase
HG718_RS03825	ENOG4105DP0	ferredoxin-NADP reductase
HG718_RS03840	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
HG718_RS03865	ENOG4105C0B	DNA polymerase III (alpha subunit)
HG718_RS03875	ENOG41062ES	Transcriptional regulator
HG718_RS03900	ENOG4108UPT	UPF0178 protein
HG718_RS03905	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
HG718_RS03915	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG718_RS03920	ENOG4105BZE	flagellar hook protein, FlgE
HG718_RS03940	ENOG4105IE4	repressor protein FlbT
HG718_RS03955	ENOG4105RQ9	TPR repeat-containing protein
HG718_RS03970	ENOG41065XG	Chemotactic signal-response protein CheL
HG718_RS03975	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG718_RS03980	ENOG4106909	Flagellar assembly regulator FliX
HG718_RS04000	ENOG4105CGA	flagellar basal-body rod protein FlgG
HG718_RS04005	ENOG4105KTQ	flagellar basal-body rod protein
HG718_RS04045	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HG718_RS04055	ENOG4105CN7	Flagellar biosynthetic protein FliP
HG718_RS04070	ENOG4108ZC9	flagellar basal-body rod protein flgc
HG718_RS04075	ENOG4105UVF	flagellar hook-basal body complex protein fliE
HG718_RS04080	ENOG41082PJ	flagellar biosynthetic protein fliQ
HG718_RS04085	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HG718_RS04090	ENOG4105D00	flagellar biosynthetic protein flhB
HG718_RS04105	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HG718_RS04115	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HG718_RS04120	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HG718_RS04125	ENOG4105EYW	Ion transport protein
HG718_RS04145	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HG718_RS04150	ENOG4105M2J	Glutaredoxin
HG718_RS04160	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HG718_RS04165	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HG718_RS04175	ENOG4107QPR	SAICAR synthetase
HG718_RS04190	ENOG4105DZG	Dehydrogenase
HG718_RS04210	ENOG4108TGR	phosphatase
HG718_RS04220	ENOG4105C83	adenylosuccinate lyase
HG718_RS04230	ENOG4105CC0	LysR family Transcriptional regulator
HG718_RS04235	ENOG4105W5Q	DNA repair protein (RadC
HG718_RS04240	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HG718_RS04245	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HG718_RS04250	ENOG4105CEV	competence damage-inducible protein
HG718_RS04280	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HG718_RS04295	ENOG41082A2	Alpha beta hydrolase
HG718_RS04305	ENOG4105CT4	transporter
HG718_RS04335	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HG718_RS04350	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS04360	ENOG4105D7W	serine acetyltransferase
HG718_RS04400	ENOG41080T7	secreted protein
HG718_RS04405	ENOG4105CT4	transporter
HG718_RS04410	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HG718_RS04450	ENOG4108Z0R	Transferase
HG718_RS04495	ENOG4108IXY	short-chain dehydrogenase reductase
HG718_RS04530	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HG718_RS04560	ENOG4108N8Y	HfaB protein
HG718_RS04595	ENOG41080XP	Cbs domain
HG718_RS04600	ENOG4105D78	K07001 NTE family protein
HG718_RS04615	ENOG4105EUJ	GTP cyclohydrolase i
HG718_RS04625	ENOG4105UTB	Blue (Type 1) copper domain protein
HG718_RS04630	ENOG4105E3B	Multicopper oxidase
HG718_RS04645	ENOG4105C22	threonyL-tRNA synthetase
HG718_RS04665	ENOG41069NU	Nitroreductase
HG718_RS04680	ENOG4107TTQ	Alpha beta hydrolase fold
HG718_RS04690	ENOG4107QI1	Mate efflux family protein
HG718_RS04695	ENOG4105D8T	Acyltransferase
HG718_RS04700	ENOG4105CI0	Citrate lyase
HG718_RS04755	ENOG4108JPW	Aminotransferase
HG718_RS04760	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HG718_RS04770	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS04790	ENOG4108VYJ	response regulator receiver protein
HG718_RS04800	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HG718_RS04810	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HG718_RS04815	ENOG4105CQB	FAD linked oxidase domain protein
HG718_RS04820	ENOG4105MP9	class II Aldolase
HG718_RS04830	ENOG4105CHR	reductase
HG718_RS04840	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HG718_RS04845	ENOG4107QR9	Iron-sulfur cluster binding protein
HG718_RS04850	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HG718_RS04875	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HG718_RS04890	ENOG4105FBD	synthase
HG718_RS04905	ENOG4105EWU	Squalene--hopene cyclase
HG718_RS04910	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HG718_RS04915	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HG718_RS04920	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HG718_RS04925	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HG718_RS04935	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HG718_RS04955	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HG718_RS04970	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HG718_RS04985	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HG718_RS04995	ENOG4105PM1	preprotein translocase subunit SecE
HG718_RS05000	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HG718_RS05010	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HG718_RS05015	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HG718_RS05020	ENOG4108VZM	50s ribosomal protein L10
HG718_RS05025	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HG718_RS05030	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG718_RS05035	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG718_RS05045	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HG718_RS05050	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HG718_RS05055	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HG718_RS05060	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HG718_RS05065	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HG718_RS05070	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HG718_RS05075	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HG718_RS05080	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HG718_RS05085	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HG718_RS05090	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HG718_RS05095	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HG718_RS05100	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HG718_RS05105	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HG718_RS05110	ENOG41083MP	50s ribosomal protein l29
HG718_RS05115	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HG718_RS05120	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HG718_RS05125	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HG718_RS05130	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HG718_RS05135	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HG718_RS05140	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HG718_RS05145	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HG718_RS05150	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HG718_RS05155	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HG718_RS05165	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HG718_RS05170	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HG718_RS05175	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HG718_RS05180	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HG718_RS05185	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HG718_RS05190	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG718_RS05195	ENOG4108ZT0	50S ribosomal protein l17
HG718_RS05200	ENOG4105C0H	protease
HG718_RS05205	ENOG4105D1H	recombination factor protein RarA
HG718_RS05210	ENOG41082CG	Protein CrcB homolog
HG718_RS05215	ENOG4105EI2	Pseudouridine synthase
HG718_RS05220	ENOG4107XGZ	Hydrolase
HG718_RS05230	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HG718_RS05235	ENOG4105DD5	Flagellar motor switch protein
HG718_RS05240	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HG718_RS05245	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HG718_RS05255	ENOG4105CJW	magnesium transporter
HG718_RS05285	ENOG4107QX3	carboxylase
HG718_RS05290	ENOG4108IPT	Naphthoate synthase
HG718_RS05310	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HG718_RS05315	ENOG4107QJE	Chromosome Partitioning Protein
HG718_RS05330	ENOG4105DZ1	carboxypeptidase
HG718_RS05340	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HG718_RS05365	ENOG4105K59	histidine triad (HIT) protein
HG718_RS05385	ENOG4105BZU	Histidine kinase
HG718_RS05395	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG718_RS05400	ENOG4105DKQ	ROK family
HG718_RS05415	ENOG4108UXN	response regulator
HG718_RS05425	ENOG4105W0E	50S ribosomal protein L33
HG718_RS05430	ENOG4108ISG	Major Facilitator
HG718_RS05450	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HG718_RS05470	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HG718_RS05475	ENOG4105CD3	dihydroorotase
HG718_RS05480	ENOG4105CXT	aspartate transcarbamylase
HG718_RS05495	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HG718_RS05500	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HG718_RS05505	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HG718_RS05510	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HG718_RS05520	ENOG4105CYM	Glutathione S-transferase
HG718_RS05535	ENOG4105C29	acyl-CoA thioesterase
HG718_RS05550	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HG718_RS05575	ENOG4105SG9	biopolymer transport protein, ExbD
HG718_RS05580	ENOG4105E02	MotA TolQ exbB proton channel
HG718_RS05600	ENOG4105C8J	)-transporter
HG718_RS05610	ENOG41077A9	carbonic anhydrase
HG718_RS05615	ENOG4105FFC	UPF0187 protein
HG718_RS05635	ENOG4105CUB	amino acid
HG718_RS05640	ENOG4107SC1	transglycosylase
HG718_RS05645	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HG718_RS05650	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HG718_RS05655	ENOG4105E50	uracil-dna glycosylase
HG718_RS05665	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG718_RS05670	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HG718_RS05690	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HG718_RS05695	ENOG4105C3F	Signal peptidase i
HG718_RS05700	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HG718_RS05710	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
HG718_RS05715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG718_RS05725	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HG718_RS05735	ENOG4105CH5	extracellular solute-binding protein, family 7
HG718_RS05740	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HG718_RS05755	ENOG4105ER2	Ompa motb domain protein
HG718_RS05760	ENOG4107RD7	Flagellar Motor Protein, MotA
HG718_RS05780	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HG718_RS05795	ENOG4105D52	delta-aminolevulinic acid dehydratase
HG718_RS05800	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HG718_RS05810	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS05815	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HG718_RS05845	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HG718_RS05850	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HG718_RS05860	ENOG4108YXV	Transcriptional regulator
HG718_RS05865	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HG718_RS05870	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HG718_RS05875	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HG718_RS05885	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HG718_RS05890	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HG718_RS05895	ENOG4107XZX	Involved in the transcription termination process (By similarity)
HG718_RS05900	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HG718_RS05905	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HG718_RS05925	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HG718_RS05930	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HG718_RS05935	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HG718_RS05940	ENOG4105WJX	transcriptional regulator MERR family
HG718_RS05955	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG718_RS06010	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HG718_RS06020	ENOG4105K4P	CoA-binding domain protein
HG718_RS06025	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS06030	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HG718_RS06035	ENOG4108UJD	30S ribosomal protein S9
HG718_RS06065	ENOG4105CHM	Aminotransferase
HG718_RS06070	ENOG4105D6E	homoserine dehydrogenase
HG718_RS06080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HG718_RS06120	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HG718_RS06135	ENOG4105CHR	reductase
HG718_RS06140	ENOG4105CG3	alpha amylase, catalytic region
HG718_RS06145	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HG718_RS06155	ENOG4105D65	subunit l
HG718_RS06160	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HG718_RS06165	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HG718_RS06180	ENOG4105KJM	monovalent cation h antiporter subunit g
HG718_RS06190	ENOG4105SC1	monovalent cation H antiporter subunit E
HG718_RS06195	ENOG4105VEQ	Cold shock protein
HG718_RS06215	ENOG4108R86	Transcriptional regulator
HG718_RS06245	ENOG4105D25	secreted protein
HG718_RS06260	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
HG718_RS06265	ENOG4105E0C	molybdate abc transporter
HG718_RS06270	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HG718_RS06275	ENOG4105C28	cystathionine
HG718_RS06280	ENOG4107QXX	ABC transporter
HG718_RS06285	ENOG4105EZ7	amino acid ABC transporter
HG718_RS06290	ENOG4105DRP	amino acid AbC transporter
HG718_RS06295	ENOG4105CDA	abc transporter atp-binding protein
HG718_RS06305	ENOG4105KHC	sulfurtransferase
HG718_RS06310	ENOG4105C6T	cysteine synthase
HG718_RS06315	ENOG4108NIX	Factor ChrR
HG718_RS06320	ENOG4107FW0	short-chain dehydrogenase reductase
HG718_RS06330	ENOG4105CT4	transporter
HG718_RS06335	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HG718_RS06350	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HG718_RS06355	ENOG4108IJ7	Glycine betaine
HG718_RS06360	ENOG4108HQS	Glycine betaine
HG718_RS06390	ENOG4108KE4	O-methyltransferase
HG718_RS06405	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HG718_RS06415	ENOG4105C01	Dihydroxy-acid dehydratase
HG718_RS06425	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG718_RS06430	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG718_RS06460	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HG718_RS06465	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
HG718_RS06470	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HG718_RS06475	ENOG4105C75	arginyL-tRNA synthetase
HG718_RS06485	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HG718_RS06495	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HG718_RS06500	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HG718_RS06505	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HG718_RS06510	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HG718_RS06515	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HG718_RS06520	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HG718_RS06525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HG718_RS06530	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HG718_RS06545	ENOG4105VIE	preprotein translocase, subunit YajC
HG718_RS06550	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HG718_RS06565	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG718_RS06575	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HG718_RS06590	ENOG4105DV0	amidase (EC 3.5.1.4
HG718_RS06605	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HG718_RS06610	ENOG4108UUM	single-stranded DNA-binding protein
HG718_RS06630	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HG718_RS06645	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HG718_RS06685	ENOG4105D7X	high-affinity nickel-transporter
HG718_RS06690	ENOG4107QPD	alcohol dehydrogenase
HG718_RS06700	ENOG4105CFC	Transporter
HG718_RS06705	ENOG4105FAV	ABC, transporter
HG718_RS06710	ENOG4105FDK	ABC transporter
HG718_RS06750	ENOG4107MKT	Stringent starvation protein a
HG718_RS06780	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HG718_RS06785	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HG718_RS06820	ENOG4108UW5	maltose o-acetyltransferase
HG718_RS06830	ENOG4105E43	Extracellular solute-binding protein, family 5
HG718_RS06845	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HG718_RS06850	ENOG4105CEY	Amp-dependent synthetase and ligase
HG718_RS06870	ENOG4105CHR	reductase
HG718_RS06895	ENOG4107NKQ	Flavinator of succinate dehydrogenase
HG718_RS06905	ENOG4105CB5	ATP-dependent DNA helicase recG
HG718_RS06910	ENOG4105BZU	Histidine kinase
HG718_RS06940	ENOG41060WC	Enoyl-CoA hydratase
HG718_RS06945	ENOG4108YYC	ycei family
HG718_RS06965	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS06980	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HG718_RS06985	ENOG4105WD1	Membrane
HG718_RS07010	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG718_RS07015	ENOG4105F8V	Hydrolase, tatD family
HG718_RS07025	ENOG4107QRG	dna polymerase iii
HG718_RS07030	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HG718_RS07035	ENOG4105DZ1	carboxypeptidase
HG718_RS07040	ENOG4105K6T	rare lipoprotein A
HG718_RS07060	ENOG4105EXG	Transcriptional regulator
HG718_RS07065	ENOG4105EUB	pirin domain protein
HG718_RS07075	ENOG4105CKI	cobalamin synthesis protein
HG718_RS07100	ENOG4105BZU	Histidine kinase
HG718_RS07135	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HG718_RS07150	ENOG4105C1J	atp-dependent rna helicase
HG718_RS07165	ENOG41060WC	Enoyl-CoA hydratase
HG718_RS07170	ENOG4107QX3	carboxylase
HG718_RS07180	ENOG4108RF4	Tetr family transcriptional regulator
HG718_RS07210	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HG718_RS07215	ENOG4105C5X	domain protein
HG718_RS07220	ENOG4105CHR	reductase
HG718_RS07230	ENOG4105CT4	transporter
HG718_RS07235	ENOG4105DXN	mazG family
HG718_RS07240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HG718_RS07245	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HG718_RS07250	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HG718_RS07255	ENOG4105C1A	potassium transporter peripheral membrane
HG718_RS07260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG718_RS07265	ENOG4105ES5	Histidine kinase
HG718_RS07270	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG718_RS07280	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG718_RS07285	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HG718_RS07290	ENOG4108ZAI	phosphatidylglycerophosphatase a
HG718_RS07295	ENOG4105CEV	competence damage-inducible protein
HG718_RS07300	ENOG4108Z1B	Cyclase dehydrase
HG718_RS07305	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HG718_RS07315	ENOG4105EE5	Membrane protein terC
HG718_RS07325	ENOG4107QN2	dihydrolipoyl dehydrogenase
HG718_RS07330	ENOG4105C7S	Dehydrogenase
HG718_RS07340	ENOG4105CPP	Dehydrogenase, E1 component
HG718_RS07345	ENOG4108JYK	Dehydrogenase
HG718_RS07370	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HG718_RS07375	ENOG4108TGY	Glutathione S-transferase
HG718_RS07415	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HG718_RS07420	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HG718_RS07425	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HG718_RS07430	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HG718_RS07435	ENOG4105BZU	Histidine kinase
HG718_RS07445	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HG718_RS07450	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HG718_RS07455	ENOG4105NTZ	Preprotein translocase subunit SecG
HG718_RS07470	ENOG4105CRQ	synthase (Component I)
HG718_RS07475	ENOG4105PXI	polysaccharide deacetylase
HG718_RS07480	ENOG4105DDQ	anthranilate synthase
HG718_RS07485	ENOG4107QYG	anthranilate phosphoribosyltransferase
HG718_RS07490	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HG718_RS07495	ENOG4105XYF	acetyltransferase
HG718_RS07500	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HG718_RS07505	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HG718_RS07515	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HG718_RS07520	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HG718_RS07525	ENOG4105BZN	citrate synthase
HG718_RS07530	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG718_RS07535	ENOG4105GYT	Protein of unknown function (DUF1009)
HG718_RS07545	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HG718_RS07550	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG718_RS07560	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG718_RS07565	ENOG4105DZP	Membrane-associated zinc metalloprotease
HG718_RS07570	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HG718_RS07580	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HG718_RS07585	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HG718_RS07590	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HG718_RS07595	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HG718_RS07600	ENOG4105CE9	30S ribosomal protein S2
HG718_RS07615	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HG718_RS07625	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HG718_RS07670	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HG718_RS07675	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HG718_RS07680	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG718_RS07685	ENOG4105C8S	subunit m
HG718_RS07690	ENOG4105D65	subunit l
HG718_RS07695	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG718_RS07700	ENOG4105DF2	NADH dehydrogenase subunit j
HG718_RS07705	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG718_RS07710	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HG718_RS07715	ENOG4107R0R	NADH dehydrogenase subunit g
HG718_RS07720	ENOG4107QIZ	NADH dehydrogenase
HG718_RS07725	ENOG4105GKE	subunit e
HG718_RS07730	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG718_RS07735	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HG718_RS07740	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG718_RS07745	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HG718_RS07755	ENOG4105BZU	Histidine kinase
HG718_RS07760	ENOG4105WH1	Two component transcriptional regulator luxr family
HG718_RS07765	ENOG4105BZU	Histidine kinase
HG718_RS07770	ENOG4105D5K	Hemolysin activator protein
HG718_RS07790	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HG718_RS07795	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HG718_RS07800	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HG718_RS07805	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HG718_RS07830	ENOG4108Z7F	N-acetyltransferase
HG718_RS07835	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HG718_RS07850	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS07870	ENOG4108YZA	Nitrogen regulatory protein pii
HG718_RS07875	ENOG4105C5F	glutamine synthetase
HG718_RS07885	ENOG4105DV0	amidase (EC 3.5.1.4
HG718_RS07890	ENOG41066U0	
HG718_RS07900	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG718_RS07905	ENOG4105C1J	atp-dependent rna helicase
HG718_RS07910	ENOG4105D25	secreted protein
HG718_RS07920	ENOG4107RGH	Aldehyde dehydrogenase
HG718_RS07930	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS07935	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS07950	ENOG4108Z4V	iron-sulfur cluster assembly
HG718_RS07955	ENOG4105VG1	fes assembly suf system protein
HG718_RS07965	ENOG4105JRK	feS assembly protein SufD
HG718_RS07970	ENOG4105C3K	feS assembly ATPase SufC
HG718_RS07985	ENOG4107QI6	Cysteine desulfurase
HG718_RS07990	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HG718_RS07995	ENOG4105DHZ	alpha beta
HG718_RS08000	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HG718_RS08005	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HG718_RS08015	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG718_RS08020	ENOG4105ED9	Protein of unknown function (DUF455)
HG718_RS08025	ENOG4105DR5	peptidase
HG718_RS08045	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HG718_RS08050	ENOG4105C03	ribonuclease
HG718_RS08050	ENOG4105C03	ribonuclease
HG718_RS08075	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HG718_RS08080	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HG718_RS08085	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HG718_RS08090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HG718_RS08095	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HG718_RS08100	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HG718_RS08120	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
HG718_RS08125	ENOG4107RTZ	reductase
HG718_RS08130	ENOG4105C9M	aspartyl-trna synthetase
HG718_RS08135	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HG718_RS08145	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HG718_RS08155	ENOG4105C02	permease
HG718_RS08160	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HG718_RS08170	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HG718_RS08175	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HG718_RS08185	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HG718_RS08190	ENOG4105C5H	ABC transporter
HG718_RS08200	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HG718_RS08215	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HG718_RS08220	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HG718_RS08230	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HG718_RS08235	ENOG4105C0A	alcohol dehydrogenase
HG718_RS08240	ENOG4105CPQ	Dehydrogenase
HG718_RS08245	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HG718_RS08250	ENOG4105DSJ	YicC domain protein
HG718_RS08255	ENOG4105HHA	aminodeoxychorismate lyase
HG718_RS08260	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG718_RS08265	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HG718_RS08275	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HG718_RS08280	ENOG4105YCT	UPF0386 protein
HG718_RS08285	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HG718_RS08290	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HG718_RS08305	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HG718_RS08315	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HG718_RS08320	ENOG4105CY3	ABC transporter, permease
HG718_RS08335	ENOG4105E96	Colicin v production protein
HG718_RS08340	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HG718_RS08345	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HG718_RS08350	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HG718_RS08355	ENOG4105DZG	Dehydrogenase
HG718_RS08365	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HG718_RS08390	ENOG4105EMU	Dehydrogenase
HG718_RS08395	ENOG4105RAK	Histidine kinase
HG718_RS08420	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG718_RS08435	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HG718_RS08445	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG718_RS08455	ENOG4108W2P	Methyl-accepting chemotaxis
HG718_RS08460	ENOG4105E6M	Sulphatase-modifying factor protein
HG718_RS08480	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS08485	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS08515	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HG718_RS08530	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HG718_RS08535	ENOG4108JJ7	ABC transporter
HG718_RS08545	ENOG4108URH	decarboxylase
HG718_RS08550	ENOG4105FR1	rard protein
HG718_RS08555	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HG718_RS08560	ENOG4105C8N	cysteinyl-tRNA synthetase
HG718_RS08565	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HG718_RS08570	ENOG4105C4K	Nad synthetase
HG718_RS08580	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG718_RS08585	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG718_RS08595	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HG718_RS08605	ENOG4105E66	phosphoriboisomerase A
HG718_RS08610	ENOG4105C26	Dehydrogenase
HG718_RS08620	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG718_RS08635	ENOG4105BZU	Histidine kinase
HG718_RS08640	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HG718_RS08645	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HG718_RS08650	ENOG4108RG0	uracil-dna glycosylase
HG718_RS08655	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS08670	ENOG4105DEN	Luciferase family
HG718_RS08675	ENOG4105D9N	nucleoside
HG718_RS08680	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HG718_RS08685	ENOG4105BZU	Histidine kinase
HG718_RS08690	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS08695	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HG718_RS08700	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS08705	ENOG4105BZU	Histidine kinase
HG718_RS08710	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS08715	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS08735	ENOG4107QKV	phosphomannomutase
HG718_RS08745	ENOG4105HF0	Membrane
HG718_RS08750	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG718_RS08755	ENOG4108TPP	exopolysaccharide synthesis
HG718_RS08770	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HG718_RS08775	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HG718_RS08780	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HG718_RS08785	ENOG4105D2B	acyl-CoA dehydrogenase
HG718_RS08795	ENOG4108U05	Transcriptional regulator
HG718_RS08815	ENOG4105CD8	aminopeptidase N
HG718_RS08820	ENOG4105BZU	Histidine kinase
HG718_RS08835	ENOG4105DU6	RNA polymerase
HG718_RS08845	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HG718_RS08860	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HG718_RS08865	ENOG4105K70	DNA-binding protein
HG718_RS08875	ENOG4108V0P	LemA family
HG718_RS08885	ENOG4105GR3	Histidine kinase
HG718_RS08890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG718_RS08900	ENOG4105KWW	Biogenesis protein
HG718_RS08905	ENOG4105DA4	cytochrome c-type biogenesis protein
HG718_RS08910	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HG718_RS08920	ENOG4106FI7	cytochrome c-type biogenesis protein
HG718_RS08930	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HG718_RS08935	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HG718_RS08955	ENOG4107S2Z	UPF0761 membrane protein
HG718_RS08965	ENOG41062D9	Histidine kinase
HG718_RS08970	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG718_RS08985	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS08990	ENOG4105D2B	acyl-CoA dehydrogenase
HG718_RS08995	ENOG4105CHR	reductase
HG718_RS09030	ENOG4105EB3	Histidine kinase
HG718_RS09045	ENOG4108ZZ3	UPF0260 protein
HG718_RS09050	ENOG4108JQC	penicillin-binding protein 1A
HG718_RS09075	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HG718_RS09085	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HG718_RS09105	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HG718_RS09110	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG718_RS09130	ENOG4105D64	Mechanosensitive ion channel
HG718_RS09155	ENOG4105BZU	Histidine kinase
HG718_RS09160	ENOG4105CSR	polyphosphate kinase 2
HG718_RS09170	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HG718_RS09245	ENOG4105BZU	Histidine kinase
HG718_RS09260	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS09270	ENOG4108NH8	Cation transport protein
HG718_RS09285	ENOG4105E0X	reductase
HG718_RS09320	ENOG4105EA8	2-Nitropropane dioxygenase
HG718_RS09350	ENOG4106NZI	LysR family Transcriptional regulator
HG718_RS09355	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS09360	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HG718_RS09400	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HG718_RS09405	ENOG4107R5W	Monooxygenase
HG718_RS09420	ENOG4107QP3	malate synthase g
HG718_RS09425	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HG718_RS09430	ENOG4105D7T	ABC transporter
HG718_RS09440	ENOG4105I5W	Transporter
HG718_RS09470	ENOG41090AP	transport protein
HG718_RS09475	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HG718_RS09480	ENOG4105EHG	Permease protein
HG718_RS09485	ENOG4107R4I	Periplasmic binding protein
HG718_RS09490	ENOG4106QJH	hemin transport protein
HG718_RS09495	ENOG4107ENK	receptor
HG718_RS09520	ENOG41074H6	response regulator
HG718_RS09545	ENOG4105VDW	Csbd family
HG718_RS09560	ENOG4105DZQ	phospholipase D Transphosphatidylase
HG718_RS09605	ENOG4105BZU	Histidine kinase
HG718_RS09615	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS09620	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS09630	ENOG4108JGH	Tetr family transcriptional regulator
HG718_RS09660	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HG718_RS09670	ENOG4105CEY	Amp-dependent synthetase and ligase
HG718_RS09675	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HG718_RS09680	ENOG4108W6C	Dehydrogenase
HG718_RS09690	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
HG718_RS09695	ENOG41076HS	cation diffusion facilitator family transporter
HG718_RS09710	ENOG4105DVC	DnaJ domain protein
HG718_RS09715	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HG718_RS09720	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HG718_RS09730	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HG718_RS09735	ENOG4107QS4	23S rRNA
HG718_RS09745	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HG718_RS09750	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HG718_RS09765	ENOG4105J7D	transcriptional regulator
HG718_RS09780	ENOG4105CSU	acyl-Coa dehydrogenase
HG718_RS09785	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HG718_RS09790	ENOG4105CQB	FAD linked oxidase domain protein
HG718_RS09805	ENOG4108RAV	Conserved protein
HG718_RS09820	ENOG4105CHR	reductase
HG718_RS09845	ENOG4107QHF	type ii secretion system protein e
HG718_RS09860	ENOG4105CEY	Amp-dependent synthetase and ligase
HG718_RS09865	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HG718_RS09875	ENOG4108I69	Glycosyl transferases group 1
HG718_RS09885	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HG718_RS09890	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HG718_RS09900	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HG718_RS09920	ENOG4108R7K	Metal Dependent Phosphohydrolase
HG718_RS09925	ENOG4107R7Y	intracellular protease Pfpi family
HG718_RS09945	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HG718_RS09950	ENOG4108IYU	L-aspartate oxidase
HG718_RS09955	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HG718_RS09960	ENOG4105CHR	reductase
HG718_RS09970	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HG718_RS09975	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HG718_RS09980	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HG718_RS09995	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG718_RS10005	ENOG4105EAH	synthase
HG718_RS10015	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HG718_RS10025	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HG718_RS10030	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HG718_RS10035	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HG718_RS10040	ENOG4105E4C	Lytic transglycosylase catalytic
HG718_RS10060	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HG718_RS10080	ENOG4105CEN	a g-specific adenine glycosylase
HG718_RS10095	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HG718_RS10110	ENOG41081E4	ATP synthase F0 subunit I
HG718_RS10115	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HG718_RS10120	ENOG4105VD1	ATP synthase subunit C
HG718_RS10125	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG718_RS10130	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HG718_RS10145	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG718_RS10150	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG718_RS10155	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HG718_RS10160	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HG718_RS10170	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HG718_RS10175	ENOG4105CUV	Homoserine Kinase
HG718_RS10195	ENOG4108UJU	UPF0301 protein
HG718_RS10200	ENOG4105BZU	Histidine kinase
HG718_RS10205	ENOG4105D9U	N-acetyltransferase
HG718_RS10210	ENOG4105C1V	Peptidase, M16
HG718_RS10215	ENOG4105D98	threonine synthase
HG718_RS10230	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HG718_RS10235	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HG718_RS10245	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HG718_RS10250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HG718_RS10255	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HG718_RS10265	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HG718_RS10275	ENOG4105CHH	sulfate transporter
HG718_RS10300	ENOG4108SGK	Tetr family transcriptional regulator
HG718_RS10325	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HG718_RS10330	ENOG4105ECY	inositol monophosphatase
HG718_RS10345	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HG718_RS10350	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HG718_RS10360	ENOG4105DR5	peptidase
HG718_RS10370	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HG718_RS10395	ENOG4105BZU	Histidine kinase
HG718_RS10405	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS10410	ENOG4108Z6B	deaminase
HG718_RS10425	ENOG4105FE9	pseudouridine synthase
HG718_RS10430	ENOG4106H78	methyltransferase
HG718_RS10435	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HG718_RS10440	ENOG4107QP8	phosphohexose isomerase
HG718_RS10460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HG718_RS10470	ENOG4105DTN	riboflavin biosynthesis protein ribF
HG718_RS10475	ENOG4108VYJ	response regulator receiver protein
HG718_RS10485	ENOG4105BZU	Histidine kinase
HG718_RS10495	ENOG4108NH8	Cation transport protein
HG718_RS10510	ENOG4105C8Q	Methyl-accepting chemotaxis
HG718_RS10515	ENOG4108ZG0	Ompa motb domain protein
HG718_RS10520	ENOG4105CHR	reductase
HG718_RS10535	ENOG4105CTQ	phosphohexokinase
HG718_RS10575	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HG718_RS10580	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HG718_RS10585	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HG718_RS10595	ENOG4105CUT	histidyl-tRNA synthetase
HG718_RS10600	ENOG4105I8F	Histidine kinase
HG718_RS10615	ENOG4105EA8	2-Nitropropane dioxygenase
HG718_RS10650	ENOG4105D74	hydrolase
HG718_RS10660	ENOG4105BZU	Histidine kinase
HG718_RS10665	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HG718_RS10675	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG718_RS10685	ENOG4105S64	Formate nitrite transporter
HG718_RS10690	ENOG4105BZ1	(ABC) transporter
HG718_RS10700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HG718_RS10710	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HG718_RS10715	ENOG4105F38	ABC transporter, permease
HG718_RS10720	ENOG4105D38	putrescine abc transporter
HG718_RS10740	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HG718_RS10745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HG718_RS10780	ENOG4107QX8	SPFH domain, Band 7 family protein
HG718_RS10785	ENOG4105C5I	Dehydrogenase
HG718_RS10800	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HG718_RS10805	ENOG4105CT3	Monooxygenase
HG718_RS10810	ENOG4105EKE	dihydroorotase
HG718_RS10840	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
HG718_RS10850	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HG718_RS10855	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HG718_RS10865	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS10890	ENOG4105CHR	reductase
HG718_RS10900	ENOG4108NVR	Methyl-accepting chemotaxis
HG718_RS10910	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HG718_RS10915	ENOG4105C03	ribonuclease
HG718_RS10920	ENOG4108Z03	MAF-like protein
HG718_RS10925	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HG718_RS10935	ENOG4108ZTZ	UPF0262 protein
HG718_RS10940	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HG718_RS10950	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HG718_RS10970	ENOG4108J2P	Alpha beta hydrolase fold
HG718_RS10975	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HG718_RS11010	ENOG4107QM2	Aldo Keto reductase
HG718_RS11035	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HG718_RS11040	ENOG4105C5Q	Transcriptional regulator
HG718_RS11065	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HG718_RS11090	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS11115	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS11170	ENOG4107QN1	sodium solute
HG718_RS11240	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
HG718_RS11255	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG718_RS11260	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS11265	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS11270	ENOG4105CSU	acyl-Coa dehydrogenase
HG718_RS11275	ENOG4108Z6Z	Transcriptional regulator
HG718_RS11290	ENOG4108VCT	Sulfite exporter TauE/SafE
HG718_RS11300	ENOG4107QIV	Cytochrome c biogenesis protein
HG718_RS11315	ENOG4107QRT	dEAD DEAH box helicase
HG718_RS11325	ENOG4107T0X	DNA ligase
HG718_RS11360	ENOG4105DVT	helicase
HG718_RS11365	ENOG4105BZU	Histidine kinase
HG718_RS11370	ENOG4105DK7	lysyl-tRNA synthetase
HG718_RS11390	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HG718_RS11395	ENOG4105K89	arsenate reductase
HG718_RS11400	ENOG4107R73	Mate efflux family protein
HG718_RS11420	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS11425	ENOG4105CAY	ferredoxin--nadp reductase
HG718_RS11465	ENOG4108Z86	Glutamine amidotransferase
HG718_RS11475	ENOG41067MG	lrgb family
HG718_RS11485	ENOG4105DHP	deoxycytidine triphosphate deaminase
HG718_RS11495	ENOG4105NWN	ApaG protein
HG718_RS11500	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HG718_RS11525	ENOG4105CWC	Acetylornithine deacetylase
HG718_RS11540	ENOG4105DBV	ornithine carbamoyltransferase
HG718_RS11545	ENOG4105C8Y	Acetylornithine aminotransferase
HG718_RS11550	ENOG4105E3A	(ABC) transporter
HG718_RS11560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG718_RS11570	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HG718_RS11580	ENOG4105C8U	phosphate abc transporter
HG718_RS11590	ENOG4105BZU	Histidine kinase
HG718_RS11610	ENOG4105WPN	DNA integration recombination invertion protein
HG718_RS11615	ENOG41062JF	Transcriptional regulator
HG718_RS11635	ENOG4105EUB	pirin domain protein
HG718_RS11650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG718_RS11660	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HG718_RS11675	ENOG4105ECQ	AraC Family Transcriptional Regulator
HG718_RS11720	ENOG4107RFY	SbcCD D subunit
HG718_RS11725	ENOG4105EYH	Exonuclease
HG718_RS11805	ENOG4108I5C	dEAD DEAH box helicase
HG718_RS11905	ENOG4105DA5	(ABC) transporter
HG718_RS11910	ENOG4105C2M	dna polymerase I
HG718_RS11920	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HG718_RS11925	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HG718_RS11930	ENOG4105EB3	Histidine kinase
HG718_RS11935	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HG718_RS11940	ENOG4105DAS	pts system
HG718_RS11945	ENOG41080Z8	PHOSPHOCARRIER protein
HG718_RS11950	ENOG4105BZU	Histidine kinase
HG718_RS11955	ENOG4105BZU	Histidine kinase
HG718_RS11960	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HG718_RS11965	ENOG4105I8F	Histidine kinase
HG718_RS11975	ENOG4107Z7P	Ferredoxin
HG718_RS11985	ENOG4105K8N	protein family UPF0079, ATPase
HG718_RS11990	ENOG4105EHM	Aminoglycoside phosphotransferase
HG718_RS11995	ENOG4108S0S	Nucleotidyl transferase
HG718_RS12005	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HG718_RS12010	ENOG4105K63	Thioredoxin
HG718_RS12020	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HG718_RS12025	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HG718_RS12030	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HG718_RS12035	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HG718_RS12040	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HG718_RS12045	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HG718_RS12060	ENOG4105E2B	Taurine dioxygenase
HG718_RS12065	ENOG4105CIF	Ornithine Cyclodeaminase
HG718_RS12075	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HG718_RS12080	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HG718_RS12085	ENOG4105CAT	Cytidine monophosphate kinase
HG718_RS12090	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HG718_RS12105	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HG718_RS12120	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HG718_RS12140	ENOG4105D7T	ABC transporter
HG718_RS12175	ENOG4105CHR	reductase
HG718_RS12180	ENOG4105KVH	Transcriptional regulator
HG718_RS12195	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HG718_RS12230	ENOG4108ZNX	Heat shock protein
HG718_RS12240	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HG718_RS12245	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
HG718_RS12250	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG718_RS12255	ENOG4108IUZ	ABC transporter
HG718_RS12270	ENOG4105C2X	Arabinose 5-phosphate isomerase
HG718_RS12290	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HG718_RS12305	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HG718_RS12340	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HG718_RS12345	ENOG4105E0K	tonB-dependent siderophore receptor
HG718_RS12370	ENOG41082BR	50S ribosomal protein L35
HG718_RS12375	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HG718_RS12380	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HG718_RS12385	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HG718_RS12390	ENOG4105EYW	Ion transport protein
HG718_RS12395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HG718_RS12500	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HG718_RS12510	ENOG4107SN7	NLP P60 protein
HG718_RS12515	ENOG4108JQ5	ABC transporter
HG718_RS12520	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HG718_RS12525	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HG718_RS12530	ENOG4105E43	Extracellular solute-binding protein, family 5
HG718_RS12545	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HG718_RS12565	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HG718_RS12575	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HG718_RS12585	ENOG4105BZG	amino acid carrier protein
HG718_RS12595	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HG718_RS12600	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HG718_RS12605	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HG718_RS12610	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HG718_RS12620	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HG718_RS12625	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HG718_RS12645	ENOG4105CAS	nag kinase
HG718_RS12650	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HG718_RS12655	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HG718_RS12660	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HG718_RS12665	ENOG4105VG0	50S ribosomal protein l34
HG718_RS12680	ENOG4107QN2	dihydrolipoyl dehydrogenase
HG718_RS12685	ENOG4105BZU	Histidine kinase
HG718_RS12690	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HG718_RS12695	ENOG4105BZP	glycoside hydrolase 15-related
HG718_RS12700	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HG718_RS12705	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HG718_RS12710	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG718_RS12715	ENOG4105KXX	peptidase s58 dmpa
HG718_RS12750	ENOG4107W7X	Aldolase
HG718_RS12790	ENOG4105D7A	ATP-binding protein
HG718_RS12800	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HG718_RS12810	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HG718_RS12815	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HG718_RS12820	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG718_RS12860	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HG718_RS12870	ENOG4108UYB	regulatoR
HG718_RS12875	ENOG4105TX3	Histidine kinase
HG718_RS12880	ENOG4105CJ1	ABC, transporter
HG718_RS12915	ENOG4105CPC	Aldo Keto reductase
HG718_RS12920	ENOG4108JQC	penicillin-binding protein 1A
HG718_RS12935	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HG718_RS12940	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HG718_RS12955	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HG718_RS12965	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HG718_RS12975	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS12980	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HG718_RS12985	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG718_RS12990	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HG718_RS12995	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HG718_RS13000	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HG718_RS13025	ENOG4105C5I	Dehydrogenase
HG718_RS13045	ENOG4108RAC	Rubrerythrin
HG718_RS13055	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HG718_RS13065	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HG718_RS13075	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HG718_RS13100	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HG718_RS13105	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HG718_RS13110	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HG718_RS13115	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HG718_RS13120	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HG718_RS13130	ENOG4105CHV	Transcription elongation factor NusA
HG718_RS13135	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HG718_RS13140	ENOG4105DUM	transcriptional regulator, lysR family
HG718_RS13155	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HG718_RS13160	ENOG4108WRK	Transcriptional regulator
HG718_RS13165	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HG718_RS13170	ENOG4107RCQ	(CBS) domain
HG718_RS13175	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HG718_RS13180	ENOG4105C9A	Phoh family
HG718_RS13185	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HG718_RS13195	ENOG41090R7	Ferric uptake
HG718_RS13200	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
HG718_RS13205	ENOG41072GX	Peptidase M22 Glycoprotease
HG718_RS13210	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HG718_RS13235	ENOG4105C31	Tryptophanyl-tRNA synthetase
HG718_RS13245	ENOG4105CJR	Integral membrane protein (MviN
HG718_RS13260	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HG718_RS13270	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HG718_RS13275	ENOG4105C6K	Malic enzyme
HG718_RS13285	ENOG4105BZU	Histidine kinase
HG718_RS13290	ENOG4105C0P	Mg chelatase subunit ChlI
HG718_RS13305	ENOG41082WC	Transport-associated protein
HG718_RS13310	ENOG41082FP	UPF0102 protein
HG718_RS13315	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HG718_RS13325	ENOG4105CSA	Coproporphyrinogen iii oxidase
HG718_RS13330	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HG718_RS13335	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HG718_RS13340	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HG718_RS13345	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HG718_RS13365	ENOG4105CFG	Acts as a chaperone (By similarity)
HG718_RS13370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HG718_RS13375	ENOG4105BZU	Histidine kinase
HG718_RS13380	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HG718_RS13385	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HG718_RS13395	ENOG4105CSM	endonuclease III
HG718_RS13415	ENOG4105K59	histidine triad (HIT) protein
HG718_RS13420	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HG718_RS13430	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HG718_RS13440	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HG718_RS13445	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HG718_RS13450	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HG718_RS13460	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HG718_RS13465	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HG718_RS13490	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HG718_RS13500	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HG718_RS13505	ENOG4105E2X	shikimate dehydrogenase
HG718_RS13510	ENOG4108UHJ	MAF-like protein
HG718_RS13515	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HG718_RS13520	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HG718_RS13530	ENOG4108YXA	Membrane
HG718_RS13535	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HG718_RS13550	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HG718_RS13560	ENOG4105C7Z	Conserved Protein
HG718_RS13570	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HG718_RS13575	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HG718_RS13580	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
HG718_RS13605	ENOG4105C8T	Leucyl-tRNA synthetase
HG718_RS13610	ENOG4105TXM	Domain of unknown function (DUF3576)
HG718_RS13620	ENOG4108UB3	Thiamine monophosphate
HG718_RS13625	ENOG4105DFA	alanine racemase domain protein
HG718_RS13640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG718_RS13670	ENOG4105CGK	Exodeoxyribonuclease III
HG718_RS13685	ENOG4105CNU	cell division protein FtsK
HG718_RS13710	ENOG4108YZA	Nitrogen regulatory protein pii
HG718_RS13730	ENOG4105K59	histidine triad (HIT) protein
HG718_RS13740	ENOG4105W49	UPF0434 protein
HG718_RS13750	ENOG4105K63	Thioredoxin
HG718_RS13785	ENOG4105E2A	Dehydrogenase
HG718_RS13810	ENOG4107XAN	XdhC and CoxI family
HG718_RS13825	ENOG4105RJZ	Transcriptional regulator
HG718_RS13830	ENOG4105EMN	RNA polymerase sigma factor
HG718_RS13845	ENOG4105CYM	Glutathione S-transferase
HG718_RS13855	ENOG4105EGS	Mechanosensitive ion channel
HG718_RS13870	ENOG4105CC0	LysR family Transcriptional regulator
HG718_RS13880	ENOG4105CHR	reductase
HG718_RS13910	ENOG4105CD3	dihydroorotase
HG718_RS13930	ENOG41080HT	Transcriptional regulator, arsr family
HG718_RS13935	ENOG4108V62	Rhodanese domain protein
HG718_RS13960	ENOG4105CKK	Glycosyl transferase, family 2
HG718_RS13970	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HG718_RS14000	ENOG4105K8R	UPF0145 protein
HG718_RS14005	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HG718_RS14015	ENOG4105DJV	ribulose-phosphate 3-epimerase
HG718_RS14020	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HG718_RS14030	ENOG4105D0M	Protease HtpX homolog
HG718_RS14045	ENOG4108IXY	short-chain dehydrogenase reductase
HG718_RS14055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG718_RS14060	ENOG410846T	CoA-transferase family III
HG718_RS14070	ENOG4108YM7	Gcn5-related n-acetyltransferase
HG718_RS14105	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HG718_RS14120	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HG718_RS14125	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HG718_RS14145	ENOG4108MUZ	hydrolase
HG718_RS14190	ENOG4105D25	secreted protein
HG718_RS14210	ENOG4108IG5	Transcriptional regulator
HG718_RS14215	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS14240	ENOG4105C59	p-type ATPase
HG718_RS14250	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HG718_RS14255	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS14270	ENOG4105J7D	transcriptional regulator
HG718_RS14275	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HG718_RS14300	ENOG4105WBV	Transcriptional regulator
HG718_RS14335	ENOG4105W3H	MtN3 and saliva related transmembrane protein
HG718_RS14345	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HG718_RS14375	ENOG4105F0N	pyrophosphate phospho-hydrolase
HG718_RS14380	ENOG4105CDH	Citrulline--aspartate ligase
HG718_RS14390	ENOG4105EF7	Transcriptional regulator
HG718_RS14405	ENOG4108Q5F	Tetr family transcriptional regulator
HG718_RS14420	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HG718_RS14430	ENOG4105K6V	RNA polymerase
HG718_RS14460	ENOG4105DFI	Membrane
HG718_RS14465	ENOG4105DFI	Membrane
HG718_RS14490	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG718_RS14495	ENOG4105KZX	Pterin carbinolamine dehydratase
HG718_RS14510	ENOG4105CPC	Aldo Keto reductase
HG718_RS14515	ENOG4108UJV	acyl-CoA thioesterase i
HG718_RS14520	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HG718_RS14535	ENOG4105HFZ	Membrane
HG718_RS14545	ENOG4107RWR	Sodium hydrogen exchanger
HG718_RS14555	ENOG4105CJ1	ABC, transporter
HG718_RS14580	ENOG4107QM5	aconitate hydratase
HG718_RS14585	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS14590	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HG718_RS14595	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HG718_RS14600	ENOG41060IM	Heme exporter protein
HG718_RS14610	ENOG4107QX9	Thiol disulfide interChange protein
HG718_RS14640	ENOG4107835	probably involved in intracellular septation (By similarity)
HG718_RS14645	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HG718_RS14650	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HG718_RS14655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HG718_RS14690	ENOG4105K5M	30s ribosomal protein S16
HG718_RS14695	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HG718_RS14700	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HG718_RS14705	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HG718_RS14710	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG718_RS14715	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG718_RS14730	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG718_RS14750	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HG718_RS14770	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HG718_RS14775	ENOG4105CI0	Citrate lyase
HG718_RS14780	ENOG4105DJG	MaoC domain protein dehydratase
HG718_RS14795	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HG718_RS14810	ENOG4105E33	succinate dehydrogenase
HG718_RS14840	ENOG4108UXE	Protein tyrosine phosphatase
HG718_RS14845	ENOG4105D6J	arsenicaL-resistance protein
HG718_RS14850	ENOG4105C26	Dehydrogenase
HG718_RS14860	ENOG4108UKI	Enoyl-CoA hydratase
HG718_RS14865	ENOG4105D6Z	AFG1 family ATPase
HG718_RS14875	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HG718_RS14885	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HG718_RS14890	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HG718_RS14900	ENOG4105C7S	Dehydrogenase
HG718_RS14910	ENOG4107QN2	dihydrolipoyl dehydrogenase
HG718_RS14915	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG718_RS14925	ENOG4105C25	Primosomal protein n'
HG718_RS14930	ENOG4105BZU	Histidine kinase
HG718_RS14935	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG718_RS14940	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HG718_RS14945	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HG718_RS14950	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HG718_RS14955	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HG718_RS14965	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HG718_RS14975	ENOG4105CN1	protease
HG718_RS14985	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HG718_RS14990	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HG718_RS15000	ENOG41067HS	methyltransferase
HG718_RS15010	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HG718_RS15015	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HG718_RS15020	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HG718_RS15025	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HG718_RS15035	ENOG4105K46	50S ribosomal protein l27
HG718_RS15040	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HG718_RS15045	ENOG4105VE1	Phosphatidylcholine synthase
HG718_RS15085	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HG718_RS15105	ENOG4108IG5	Transcriptional regulator
HG718_RS15115	ENOG4105BZU	Histidine kinase
HG718_RS15130	ENOG4105CYC	Transferase
HG718_RS15135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HG718_RS15160	ENOG4107B57	rieske 2fe-2S domain-containing protein
HG718_RS15165	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HG718_RS15180	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HG718_RS15185	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HG718_RS15205	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HG718_RS15210	ENOG4105CC9	acyl-Coa dehydrogenase
HG718_RS15215	ENOG4105D2B	acyl-CoA dehydrogenase
HG718_RS15225	ENOG4105EA8	2-Nitropropane dioxygenase
HG718_RS15250	ENOG4105C94	Transporter
HG718_RS15265	ENOG4107R13	MMPL domain protein
HG718_RS15270	ENOG4105BZS	acriflavin resistance protein
HG718_RS15275	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HG718_RS15295	ENOG4105CHU	acetyl-coa acetyltransferase
HG718_RS15305	ENOG4105EUZ	Beta-lactamase domain protein
HG718_RS15355	ENOG4105E39	Enoyl-CoA hydratase
HG718_RS15365	ENOG4108K3A	Glutathione S-transferase
HG718_RS15375	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HG718_RS15380	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG718_RS15385	ENOG4105C1G	acyl-Coa dehydrogenase
HG718_RS15435	ENOG4105FE5	Homospermidine synthase
HG718_RS15445	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HG718_RS15450	ENOG4105C5Q	Transcriptional regulator
HG718_RS15455	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG718_RS15460	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HG718_RS15465	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HG718_RS15490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG718_RS15495	ENOG4108REZ	Imidazole glycerol phosphate synthase
HG718_RS15500	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HG718_RS15540	ENOG4105EY8	ABC transporter
HG718_RS15550	ENOG4105CAQ	asparagine synthetase
HG718_RS15555	ENOG4105CMR	udp-glucose 4-epimerase