locus-tag	class	description
FPZ52_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPZ52_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPZ52_RS00030	COG0435	Glutathione S-transferase
FPZ52_RS00035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FPZ52_RS00040	COG0242	peptide deformylase activity
FPZ52_RS00050	COG0242	peptide deformylase activity
FPZ52_RS00055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FPZ52_RS00060	COG2860	membrane
FPZ52_RS00065	COG0328	RNA-DNA hybrid ribonuclease activity
FPZ52_RS00070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FPZ52_RS00075	COG1238	metal cluster binding
FPZ52_RS00085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FPZ52_RS00090	COG1758	RNA polymerase activity
FPZ52_RS00105	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FPZ52_RS00115	COG0736	holo-[acyl-carrier-protein] synthase activity
FPZ52_RS00120	COG0681	Belongs to the peptidase S26 family
FPZ52_RS00125	COG0571	ribonuclease III activity
FPZ52_RS00135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPZ52_RS00145	COG1381	Involved in DNA repair and RecF pathway recombination
FPZ52_RS00170	COG3383	formate dehydrogenase (NAD+) activity
FPZ52_RS00180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPZ52_RS00185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FPZ52_RS00200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPZ52_RS00210	COG0284	orotidine-5'-phosphate decarboxylase activity
FPZ52_RS00255	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS00260	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS00265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS00270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPZ52_RS00270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS00275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS00330	COG0246	Mannitol dehydrogenase
FPZ52_RS00365	COG2188	Transcriptional regulator
FPZ52_RS00370	COG3842	ATPase activity
FPZ52_RS00390	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FPZ52_RS00395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS00400	COG4558	Periplasmic binding protein
FPZ52_RS00405	COG3720	iron ion transport
FPZ52_RS00420	COG0811	peptide transport
FPZ52_RS00440	COG0587	DNA-directed DNA polymerase activity
FPZ52_RS00460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPZ52_RS00470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FPZ52_RS00475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FPZ52_RS00480	COG0424	maF-like protein
FPZ52_RS00485	COG1530	ribonuclease E activity
FPZ52_RS00490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FPZ52_RS00525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FPZ52_RS00550	COG1652	LysM domain
FPZ52_RS00555	COG0662	Cupin 2, conserved barrel domain protein
FPZ52_RS00555	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FPZ52_RS00560	COG0297	glycogen (starch) synthase activity
FPZ52_RS00610	COG0842	Transport permease protein
FPZ52_RS00615	COG1131	(ABC) transporter
FPZ52_RS00620	COG1132	(ABC) transporter
FPZ52_RS00625	COG1132	(ABC) transporter
FPZ52_RS00630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FPZ52_RS00635	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS00665	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPZ52_RS00680	COG2096	Adenosyltransferase
FPZ52_RS00690	COG0300	oxidoreductase activity
FPZ52_RS00700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPZ52_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPZ52_RS00730	COG0250	Participates in transcription elongation, termination and antitermination
FPZ52_RS00735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FPZ52_RS00740	COG0081	regulation of translation
FPZ52_RS00745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FPZ52_RS00750	COG0222	ribosome binding
FPZ52_RS00755	COG0085	RNA polymerase activity
FPZ52_RS00765	COG0697	spore germination
FPZ52_RS00770	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FPZ52_RS00775	COG0049	tRNA binding
FPZ52_RS00780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPZ52_RS00785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPZ52_RS00790	COG0051	transcription antitermination factor activity, RNA binding
FPZ52_RS00795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FPZ52_RS00800	COG0088	Forms part of the polypeptide exit tunnel
FPZ52_RS00805	COG0089	rRNA binding
FPZ52_RS00810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FPZ52_RS00815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FPZ52_RS00820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FPZ52_RS00825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FPZ52_RS00830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FPZ52_RS00840	COG0255	Belongs to the universal ribosomal protein uL29 family
FPZ52_RS00845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FPZ52_RS00850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FPZ52_RS00855	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FPZ52_RS00860	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FPZ52_RS00865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FPZ52_RS00870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FPZ52_RS00875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FPZ52_RS00880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FPZ52_RS00885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FPZ52_RS00890	COG1841	ribosomal large subunit assembly
FPZ52_RS00895	COG0200	Binds to the 23S rRNA
FPZ52_RS00905	COG0563	adenylate kinase activity
FPZ52_RS00910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FPZ52_RS00915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FPZ52_RS00920	COG0202	RNA polymerase activity
FPZ52_RS00925	COG0203	ribosomal protein L17
FPZ52_RS00935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FPZ52_RS00945	COG0124	histidyl-tRNA synthetase
FPZ52_RS00955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FPZ52_RS00960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPZ52_RS00965	COG1116	anion transmembrane transporter activity
FPZ52_RS00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FPZ52_RS00975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPZ52_RS00985	COG0352	thiamine-phosphate diphosphorylase activity
FPZ52_RS00990	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FPZ52_RS01000	COG0584	glycerophosphoryl diester phosphodiesterase
FPZ52_RS01005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPZ52_RS01010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPZ52_RS01040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FPZ52_RS01045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPZ52_RS01060	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS01085	COG2835	tetraacyldisaccharide 4'-kinase activity
FPZ52_RS01090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPZ52_RS01095	COG0154	amidase activity
FPZ52_RS01100	COG0436	Aminotransferase
FPZ52_RS01105	COG2261	transglycosylase associated protein
FPZ52_RS01105	COG1674	ftsk spoiiie
FPZ52_RS01135	COG0564	pseudouridine synthase activity
FPZ52_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS01145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPZ52_RS01150	COG0569	domain protein
FPZ52_RS01155	COG0450	alkyl hydroperoxide reductase
FPZ52_RS01165	COG1185	polyribonucleotide nucleotidyltransferase activity
FPZ52_RS01170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FPZ52_RS01180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FPZ52_RS01190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FPZ52_RS01195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FPZ52_RS01200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FPZ52_RS01210	COG1194	a g-specific adenine glycosylase
FPZ52_RS01225	COG1663	tetraacyldisaccharide 4'-kinase activity
FPZ52_RS01230	COG1519	Transferase
FPZ52_RS01245	COG0312	modulator of DNA gyrase
FPZ52_RS01280	COG1802	Transcriptional regulator
FPZ52_RS01285	COG0306	phosphate transporter
FPZ52_RS01315	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPZ52_RS01320	COG0567	Dehydrogenase, E1 component
FPZ52_RS01335	COG0045	succinate-CoA ligase (ADP-forming) activity
FPZ52_RS01390	COG0513	Belongs to the DEAD box helicase family
FPZ52_RS01395	COG0813	purine-nucleoside phosphorylase activity
FPZ52_RS01405	COG2197	response regulator
FPZ52_RS01425	COG0730	response to heat
FPZ52_RS01430	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS01440	COG3845	ABC transporter
FPZ52_RS01445	COG1744	ABC transporter substrate-binding protein PnrA-like
FPZ52_RS01460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FPZ52_RS01470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPZ52_RS01475	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS01480	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS01485	COG3845	ABC transporter
FPZ52_RS01505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FPZ52_RS01510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPZ52_RS01515	COG0287	Prephenate dehydrogenase
FPZ52_RS01530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FPZ52_RS01550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPZ52_RS01565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FPZ52_RS01570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FPZ52_RS01575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FPZ52_RS01580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FPZ52_RS01605	COG2983	Belongs to the UPF0260 family
FPZ52_RS01610	COG0196	riboflavin kinase activity
FPZ52_RS01620	COG0655	NAD(P)H dehydrogenase (quinone) activity
FPZ52_RS01625	COG1227	inorganic diphosphatase activity
FPZ52_RS01635	COG0459	protein refolding
FPZ52_RS01640	COG3153	acetyltransferase
FPZ52_RS01650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FPZ52_RS01655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FPZ52_RS01665	COG0071	Belongs to the small heat shock protein (HSP20) family
FPZ52_RS01675	COG0492	ferredoxin-NADP+ reductase activity
FPZ52_RS01680	COG1522	sequence-specific DNA binding
FPZ52_RS01685	COG1496	oxidoreductase activity
FPZ52_RS01695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FPZ52_RS01715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPZ52_RS01725	COG1435	thymidine kinase activity
FPZ52_RS01730	COG3507	Belongs to the glycosyl hydrolase 43 family
FPZ52_RS01740	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS01745	COG1175	transmembrane transport
FPZ52_RS01775	COG0811	peptide transport
FPZ52_RS01780	COG1132	(ABC) transporter
FPZ52_RS01785	COG1120	ATPase activity
FPZ52_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS01795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS01800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FPZ52_RS01805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPZ52_RS01805	COG2207	Transcriptional regulator
FPZ52_RS01810	COG4774	siderophore transport
FPZ52_RS01820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FPZ52_RS01820	COG0321	lipoyl(octanoyl) transferase activity
FPZ52_RS01825	COG0084	hydrolase, TatD family'
FPZ52_RS01835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FPZ52_RS01840	COG1686	Belongs to the peptidase S11 family
FPZ52_RS01845	COG2066	Belongs to the glutaminase family
FPZ52_RS01850	COG1115	amino acid carrier protein
FPZ52_RS01860	COG3842	ATPase activity
FPZ52_RS01865	COG3842	ATPase activity
FPZ52_RS01875	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS01890	COG2847	Copper chaperone PCu(A)C
FPZ52_RS01910	COG0129	dihydroxy-acid dehydratase activity
FPZ52_RS01915	COG2186	Transcriptional regulator
FPZ52_RS01925	COG1129	ABC transporter
FPZ52_RS01930	COG4214	carbohydrate transport
FPZ52_RS01935	COG4213	ABC transporter substrate-binding protein
FPZ52_RS01940	COG1940	carbohydrate kinase activity
FPZ52_RS01950	COG1858	cytochrome C peroxidase
FPZ52_RS01955	COG2115	Belongs to the xylose isomerase family
FPZ52_RS01965	COG0033	Phosphoglucomutase
FPZ52_RS01970	COG0740	serine-type endopeptidase activity
FPZ52_RS01975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FPZ52_RS01995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FPZ52_RS02000	COG0439	Biotin carboxylase
FPZ52_RS02010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPZ52_RS02025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPZ52_RS02060	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS02095	COG3750	Belongs to the UPF0335 family
FPZ52_RS02105	COG0596	Alpha beta hydrolase
FPZ52_RS02115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FPZ52_RS02130	COG0281	malic enzyme
FPZ52_RS02130	COG0280	phosphate acetyltransferase
FPZ52_RS02140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FPZ52_RS02145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FPZ52_RS02150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FPZ52_RS02155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FPZ52_RS02175	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPZ52_RS02175	COG1024	Enoyl-CoA hydratase
FPZ52_RS02185	COG0183	Belongs to the thiolase family
FPZ52_RS02195	COG1960	acyl-CoA dehydrogenase activity
FPZ52_RS02220	COG0534	Mate efflux family protein
FPZ52_RS02235	COG0737	Belongs to the 5'-nucleotidase family
FPZ52_RS02250	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FPZ52_RS02255	COG1278	Cold shock
FPZ52_RS02260	COG1393	Belongs to the ArsC family
FPZ52_RS02275	COG3220	belongs to the UPF0276 family
FPZ52_RS02285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPZ52_RS02290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPZ52_RS02305	COG0540	Belongs to the ATCase OTCase family
FPZ52_RS02310	COG1573	uracil-dna glycosylase
FPZ52_RS02315	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPZ52_RS02335	COG1678	Uncharacterized ACR, COG1678
FPZ52_RS02340	COG0009	L-threonylcarbamoyladenylate synthase
FPZ52_RS02345	COG1960	acyl-CoA dehydrogenase activity
FPZ52_RS02370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FPZ52_RS02380	COG0746	molybdenum cofactor guanylyltransferase activity
FPZ52_RS02385	COG1763	Mo-molybdopterin cofactor biosynthetic process
FPZ52_RS02415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FPZ52_RS02420	COG0142	geranyltranstransferase activity
FPZ52_RS02430	COG2890	protein-(glutamine-N5) methyltransferase activity
FPZ52_RS02450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPZ52_RS02455	COG0165	Argininosuccinate lyase
FPZ52_RS02480	COG2884	Cell division ATP-binding protein ftsE
FPZ52_RS02510	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS02540	COG0469	pyruvate kinase activity
FPZ52_RS02545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FPZ52_RS02550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FPZ52_RS02555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FPZ52_RS02570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPZ52_RS02570	COG0072	phenylalanine-tRNA ligase activity
FPZ52_RS02580	COG0625	glutathione transferase activity
FPZ52_RS02595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FPZ52_RS02600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FPZ52_RS02615	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FPZ52_RS02615	COG3264	Mechanosensitive ion channel
FPZ52_RS02640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FPZ52_RS02650	COG0737	Belongs to the 5'-nucleotidase family
FPZ52_RS02655	COG2816	NAD+ diphosphatase activity
FPZ52_RS02665	COG0077	Prephenate dehydratase
FPZ52_RS02665	COG1605	Chorismate mutase
FPZ52_RS02675	COG4166	transmembrane transport
FPZ52_RS02680	COG4174	ABC transporter (Permease)
FPZ52_RS02685	COG4239	(ABC) transporter, permease
FPZ52_RS02690	COG4172	Belongs to the ABC transporter superfamily
FPZ52_RS02715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FPZ52_RS02720	COG2813	Specifically methylates the guanine in position
FPZ52_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS02735	COG0408	coproporphyrinogen oxidase activity
FPZ52_RS02740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FPZ52_RS02745	COG0181	hydroxymethylbilane synthase activity
FPZ52_RS02755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPZ52_RS02765	COG4459	periplasmic nitrate reductase
FPZ52_RS02780	COG3043	anaerobic respiration
FPZ52_RS02785	COG3005	denitrification pathway
FPZ52_RS02795	COG0596	Alpha beta hydrolase
FPZ52_RS02795	COG2945	thiolester hydrolase activity
FPZ52_RS02800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FPZ52_RS02810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPZ52_RS02820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPZ52_RS02825	COG1702	phosphate starvation-inducible protein PhoH
FPZ52_RS02830	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FPZ52_RS02835	COG1253	flavin adenine dinucleotide binding
FPZ52_RS02840	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FPZ52_RS02845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPZ52_RS02850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FPZ52_RS02855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPZ52_RS02860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FPZ52_RS02865	COG0539	negative regulation of cytoplasmic translation
FPZ52_RS02870	COG0776	regulation of translation
FPZ52_RS02880	COG0135	phosphoribosylanthranilate isomerase activity
FPZ52_RS02885	COG0159	tryptophan synthase activity
FPZ52_RS02905	COG0133	tryptophan synthase activity
FPZ52_RS02915	COG0525	valine-tRNA ligase activity
FPZ52_RS02925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FPZ52_RS02930	COG0583	DNA-binding transcription factor activity
FPZ52_RS02935	COG0483	inositol monophosphate 1-phosphatase activity
FPZ52_RS02960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPZ52_RS02970	COG1832	CoA-binding protein
FPZ52_RS02975	COG0140	phosphoribosyl-ATP diphosphatase activity
FPZ52_RS02980	COG0107	imidazoleglycerol-phosphate synthase activity
FPZ52_RS02990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FPZ52_RS03000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FPZ52_RS03005	COG0131	Imidazoleglycerol-phosphate dehydratase
FPZ52_RS03025	COG0346	lactoylglutathione lyase activity
FPZ52_RS03030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FPZ52_RS03040	COG0384	phenazine biosynthesis protein PhzF
FPZ52_RS03050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FPZ52_RS03055	COG1957	nucleoside hydrolase
FPZ52_RS03060	COG3956	TIGRFAM MazG family protein
FPZ52_RS03070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FPZ52_RS03075	COG2890	protein-(glutamine-N5) methyltransferase activity
FPZ52_RS03085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPZ52_RS03090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FPZ52_RS03100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FPZ52_RS03115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPZ52_RS03135	COG2095	MarC family integral membrane protein
FPZ52_RS03140	COG0488	(ABC) transporter
FPZ52_RS03145	COG0105	UTP biosynthetic process
FPZ52_RS03160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPZ52_RS03170	COG1830	Aldolase
FPZ52_RS03175	COG0126	phosphoglycerate kinase activity
FPZ52_RS03195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FPZ52_RS03200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FPZ52_RS03205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FPZ52_RS03225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPZ52_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS03235	COG0837	glucose binding
FPZ52_RS03240	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS03245	COG0444	Belongs to the ABC transporter superfamily
FPZ52_RS03250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS03255	COG0601	transmembrane transport
FPZ52_RS03260	COG0006	proline dipeptidase activity
FPZ52_RS03265	COG0747	negative chemotaxis
FPZ52_RS03270	COG0546	phosphoglycolate phosphatase activity
FPZ52_RS03290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPZ52_RS03295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPZ52_RS03300	COG0649	NAD binding
FPZ52_RS03330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FPZ52_RS03335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPZ52_RS03345	COG0713	ATP synthesis coupled electron transport
FPZ52_RS03360	COG1007	ATP synthesis coupled electron transport
FPZ52_RS03370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FPZ52_RS03380	COG0513	Belongs to the DEAD box helicase family
FPZ52_RS03390	COG1764	response to oxidative stress
FPZ52_RS03400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FPZ52_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS03410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPZ52_RS03420	COG0805	protein transport
FPZ52_RS03430	COG1196	nuclear chromosome segregation
FPZ52_RS03430	COG0741	lytic transglycosylase activity
FPZ52_RS03430	COG0739	heme binding
FPZ52_RS03435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FPZ52_RS03440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FPZ52_RS03445	COG4221	oxidoreductase activity
FPZ52_RS03470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FPZ52_RS03490	COG1127	ABC transporter
FPZ52_RS03495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPZ52_RS03500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPZ52_RS03505	COG0215	cysteine-tRNA ligase activity
FPZ52_RS03510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPZ52_RS03520	COG2814	Major facilitator Superfamily
FPZ52_RS03525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPZ52_RS03540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPZ52_RS03545	COG0363	glucosamine-6-phosphate deaminase activity
FPZ52_RS03550	COG0166	Belongs to the GPI family
FPZ52_RS03555	COG0148	phosphopyruvate hydratase activity
FPZ52_RS03560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPZ52_RS03565	COG0358	DNA primase activity
FPZ52_RS03575	COG1733	regulation of RNA biosynthetic process
FPZ52_RS03600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPZ52_RS03600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPZ52_RS03620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPZ52_RS03620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPZ52_RS03625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FPZ52_RS03630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPZ52_RS03665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FPZ52_RS03680	COG0488	(ABC) transporter
FPZ52_RS03685	COG0405	Gamma-glutamyltransferase
FPZ52_RS03690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPZ52_RS03705	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FPZ52_RS03735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FPZ52_RS03740	COG0243	molybdopterin cofactor binding
FPZ52_RS03750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPZ52_RS03755	COG1116	anion transmembrane transporter activity
FPZ52_RS03760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPZ52_RS03765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPZ52_RS03770	COG1116	anion transmembrane transporter activity
FPZ52_RS03770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPZ52_RS03775	COG3707	response regulator
FPZ52_RS03780	COG3257	ureidoglycine aminohydrolase activity
FPZ52_RS03785	COG1414	Transcriptional regulator
FPZ52_RS03790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPZ52_RS03795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPZ52_RS03800	COG3616	Alanine racemase, N-terminal domain
FPZ52_RS03805	COG2423	ornithine cyclodeaminase activity
FPZ52_RS03815	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FPZ52_RS03825	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FPZ52_RS03835	COG2351	hydroxyisourate hydrolase activity
FPZ52_RS03840	COG0583	DNA-binding transcription factor activity
FPZ52_RS03855	COG3386	PFAM SMP-30 Gluconolaconase
FPZ52_RS03860	COG0800	Aldolase
FPZ52_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS03880	COG0028	Belongs to the TPP enzyme family
FPZ52_RS03895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPZ52_RS03915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPZ52_RS03940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPZ52_RS03975	COG0156	8-amino-7-oxononanoate synthase activity
FPZ52_RS03980	COG1426	Protein conserved in bacteria
FPZ52_RS03985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FPZ52_RS04000	COG0436	Aminotransferase
FPZ52_RS04010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FPZ52_RS04015	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FPZ52_RS04030	COG0739	heme binding
FPZ52_RS04035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FPZ52_RS04045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FPZ52_RS04050	COG0477	Major facilitator Superfamily
FPZ52_RS04075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FPZ52_RS04080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FPZ52_RS04080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FPZ52_RS04095	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPZ52_RS04105	COG2133	pyrroloquinoline quinone binding
FPZ52_RS04115	COG0359	binds to the 23S rRNA
FPZ52_RS04120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FPZ52_RS04125	COG0360	Binds together with S18 to 16S ribosomal RNA
FPZ52_RS04130	COG2353	YceI-like domain
FPZ52_RS04135	COG0248	Ppx GppA phosphatase
FPZ52_RS04140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FPZ52_RS04170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPZ52_RS04180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPZ52_RS04185	COG3038	cytochrome b561
FPZ52_RS04190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPZ52_RS04200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPZ52_RS04210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPZ52_RS04215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPZ52_RS04230	COG4695	Portal protein
FPZ52_RS04335	COG1309	transcriptional regulator
FPZ52_RS04340	COG2326	polyphosphate kinase activity
FPZ52_RS04345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FPZ52_RS04370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPZ52_RS04370	COG0519	Catalyzes the synthesis of GMP from XMP
FPZ52_RS04390	COG0697	spore germination
FPZ52_RS04410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPZ52_RS04410	COG3743	rRNA binding
FPZ52_RS04415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FPZ52_RS04425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FPZ52_RS04430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FPZ52_RS04435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FPZ52_RS04470	COG1612	heme a metabolic process
FPZ52_RS04480	COG0747	negative chemotaxis
FPZ52_RS04485	COG0601	transmembrane transport
FPZ52_RS04490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS04510	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS04515	COG0305	Participates in initiation and elongation during chromosome replication
FPZ52_RS04520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPZ52_RS04530	COG0418	dihydroorotase activity
FPZ52_RS04535	COG0829	nickel cation binding
FPZ52_RS04540	COG0831	urea catabolic process
FPZ52_RS04545	COG0832	Belongs to the urease beta subunit family
FPZ52_RS04555	COG0804	urea catabolic process
FPZ52_RS04570	COG0830	nickel cation binding
FPZ52_RS04575	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FPZ52_RS04580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FPZ52_RS04595	COG0175	sulfate reduction
FPZ52_RS04615	COG1522	sequence-specific DNA binding
FPZ52_RS04620	COG2962	Rard protein
FPZ52_RS04635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPZ52_RS04655	COG1160	GTP binding
FPZ52_RS04665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FPZ52_RS04670	COG1862	Preprotein translocase
FPZ52_RS04675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPZ52_RS04680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPZ52_RS04685	COG3737	Protein of unknown function (DUF498/DUF598)
FPZ52_RS04690	COG4133	protoheme IX ABC transporter activity
FPZ52_RS04695	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPZ52_RS04700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPZ52_RS04710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPZ52_RS04715	COG3108	Peptidase M15
FPZ52_RS04725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPZ52_RS04745	COG0433	COG0433 Predicted ATPase
FPZ52_RS04750	COG4536	flavin adenine dinucleotide binding
FPZ52_RS04755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPZ52_RS04760	COG5425	PFAM Usg family protein
FPZ52_RS04770	COG1238	metal cluster binding
FPZ52_RS04805	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FPZ52_RS04820	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS04825	COG0667	Aldo Keto reductase
FPZ52_RS04835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPZ52_RS04840	COG0052	Belongs to the universal ribosomal protein uS2 family
FPZ52_RS04850	COG2313	pseudouridylate synthase activity
FPZ52_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS04875	COG4166	transmembrane transport
FPZ52_RS04885	COG2814	Major facilitator Superfamily
FPZ52_RS04890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FPZ52_RS04915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPZ52_RS04930	COG0569	domain protein
FPZ52_RS04935	COG2204	response regulator
FPZ52_RS04940	COG5000	phosphorelay sensor kinase activity
FPZ52_RS04945	COG2204	response regulator
FPZ52_RS04950	COG3852	Histidine kinase
FPZ52_RS04955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPZ52_RS04960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FPZ52_RS04960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FPZ52_RS04970	COG1058	Belongs to the CinA family
FPZ52_RS04970	COG1546	Belongs to the CinA family
FPZ52_RS04975	COG2867	negative regulation of translational initiation
FPZ52_RS04980	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FPZ52_RS04990	COG2010	Cytochrome c
FPZ52_RS04995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FPZ52_RS05015	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS05035	COG2084	Dehydrogenase
FPZ52_RS05040	COG0729	surface antigen
FPZ52_RS05055	COG5002	protein histidine kinase activity
FPZ52_RS05070	COG0194	GDP metabolic process
FPZ52_RS05080	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FPZ52_RS05140	COG4214	carbohydrate transport
FPZ52_RS05155	COG1012	belongs to the aldehyde dehydrogenase family
FPZ52_RS05175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS05185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPZ52_RS05190	COG3246	L-lysine catabolic process to acetate
FPZ52_RS05195	COG3485	protocatechuate 3,4-dioxygenase
FPZ52_RS05200	COG3485	protocatechuate 3,4-dioxygenase
FPZ52_RS05205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FPZ52_RS05210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPZ52_RS05215	COG0583	DNA-binding transcription factor activity
FPZ52_RS05220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPZ52_RS05230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPZ52_RS05235	COG2207	Transcriptional regulator
FPZ52_RS05240	COG1653	transport
FPZ52_RS05250	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS05275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FPZ52_RS05290	COG1196	nuclear chromosome segregation
FPZ52_RS05290	COG0739	heme binding
FPZ52_RS05290	COG0741	lytic transglycosylase activity
FPZ52_RS05295	COG0629	single-stranded DNA binding
FPZ52_RS05305	COG0321	lipoyl(octanoyl) transferase activity
FPZ52_RS05320	COG1610	YqeY-like protein
FPZ52_RS05325	COG0505	Belongs to the CarA family
FPZ52_RS05335	COG1802	Transcriptional regulator
FPZ52_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPZ52_RS05355	COG1522	sequence-specific DNA binding
FPZ52_RS05360	COG1522	sequence-specific DNA binding
FPZ52_RS05375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPZ52_RS05380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FPZ52_RS05390	COG3773	Cell wall hydrolase
FPZ52_RS05390	COG3409	Peptidoglycan-binding domain 1 protein
FPZ52_RS05405	COG0752	glycyl-tRNA synthetase alpha subunit
FPZ52_RS05415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPZ52_RS05420	COG1469	GTP cyclohydrolase I activity
FPZ52_RS05430	COG0625	glutathione transferase activity
FPZ52_RS05435	COG2917	probably involved in intracellular septation
FPZ52_RS05445	COG1285	pathogenesis
FPZ52_RS05455	COG0552	protein localization to endoplasmic reticulum
FPZ52_RS05460	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FPZ52_RS05465	COG1570	exodeoxyribonuclease VII activity
FPZ52_RS05470	COG0151	Belongs to the GarS family
FPZ52_RS05480	COG0217	transcriptional regulatory protein
FPZ52_RS05485	COG0471	metal ion transport
FPZ52_RS05485	COG3273	potassium ion transport
FPZ52_RS05490	COG1692	metallophosphoesterase
FPZ52_RS05495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPZ52_RS05500	COG2239	Acts as a magnesium transporter
FPZ52_RS05505	COG0483	inositol monophosphate 1-phosphatase activity
FPZ52_RS05515	COG0583	DNA-binding transcription factor activity
FPZ52_RS05525	COG0670	Belongs to the BI1 family
FPZ52_RS05535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FPZ52_RS05540	COG0343	queuine tRNA-ribosyltransferase activity
FPZ52_RS05545	COG0189	ligase activity
FPZ52_RS05545	COG4067	protein conserved in archaea
FPZ52_RS05550	COG2151	metal-sulfur cluster biosynthetic enzyme
FPZ52_RS05555	COG0316	Belongs to the HesB IscA family
FPZ52_RS05560	COG0149	triose-phosphate isomerase activity
FPZ52_RS05575	COG4235	cytochrome complex assembly
FPZ52_RS05580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FPZ52_RS05585	COG0730	response to heat
FPZ52_RS05590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPZ52_RS05595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FPZ52_RS05600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FPZ52_RS05615	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FPZ52_RS05625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPZ52_RS05630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FPZ52_RS05640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPZ52_RS05645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FPZ52_RS05650	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS05660	COG3264	Mechanosensitive ion channel
FPZ52_RS05660	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FPZ52_RS05670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPZ52_RS05675	COG0415	Belongs to the DNA photolyase family
FPZ52_RS05690	COG2059	Chromate
FPZ52_RS05700	COG0114	fumarate hydratase activity
FPZ52_RS05705	COG2321	neutral zinc metallopeptidase
FPZ52_RS05735	COG0785	Cytochrome C biogenesis protein
FPZ52_RS05745	COG1530	ribonuclease E activity
FPZ52_RS05760	COG0047	phosphoribosylformylglycinamidine synthase activity
FPZ52_RS05765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPZ52_RS05770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FPZ52_RS05790	COG2166	iron-sulfur cluster assembly
FPZ52_RS05800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FPZ52_RS05805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPZ52_RS05810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPZ52_RS05815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FPZ52_RS05820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FPZ52_RS05830	COG1024	Enoyl-CoA hydratase
FPZ52_RS05835	COG3088	subunit of a heme lyase
FPZ52_RS05840	COG1138	Cytochrome C-type biogenesis protein
FPZ52_RS05845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FPZ52_RS05850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FPZ52_RS05855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FPZ52_RS05865	COG0583	DNA-binding transcription factor activity
FPZ52_RS05870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPZ52_RS05875	COG0271	Belongs to the BolA IbaG family
FPZ52_RS05880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FPZ52_RS05900	COG1609	Transcriptional regulator
FPZ52_RS05905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPZ52_RS05915	COG0747	negative chemotaxis
FPZ52_RS05920	COG0601	transmembrane transport
FPZ52_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS05940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPZ52_RS05955	COG0719	Fe-S assembly protein
FPZ52_RS05960	COG0396	ATPase activity
FPZ52_RS05965	COG0719	Fe-S assembly protein
FPZ52_RS05980	COG2945	thiolester hydrolase activity
FPZ52_RS05990	COG0538	isocitrate dehydrogenase activity
FPZ52_RS06005	COG1217	gtp-binding protein TYPA
FPZ52_RS06010	COG1741	Belongs to the pirin family
FPZ52_RS06015	COG1363	Peptidase, m42
FPZ52_RS06020	COG0825	malonyl-CoA metabolic process
FPZ52_RS06035	COG1278	Cold shock
FPZ52_RS06040	COG0259	pyridoxamine-phosphate oxidase activity
FPZ52_RS06045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FPZ52_RS06050	COG1280	lysine exporter protein (LysE YggA)
FPZ52_RS06055	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FPZ52_RS06065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPZ52_RS06070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPZ52_RS06085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FPZ52_RS06100	COG0303	'Molybdopterin
FPZ52_RS06105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FPZ52_RS06110	COG0658	competence protein
FPZ52_RS06110	COG2333	competence protein COMEC
FPZ52_RS06115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPZ52_RS06120	COG0372	Belongs to the citrate synthase family
FPZ52_RS06145	COG2968	Membrane
FPZ52_RS06160	COG1329	Transcriptional regulator
FPZ52_RS06165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPZ52_RS06170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FPZ52_RS06180	COG0457	Tetratricopeptide repeat
FPZ52_RS06210	COG2308	Evidence 4 Homologs of previously reported genes of
FPZ52_RS06225	COG0564	pseudouridine synthase activity
FPZ52_RS06230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPZ52_RS06295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPZ52_RS06325	COG0330	HflC and HflK could
FPZ52_RS06365	COG0300	oxidoreductase activity
FPZ52_RS06400	COG0583	DNA-binding transcription factor activity
FPZ52_RS06460	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FPZ52_RS06465	COG3421	Type III restriction
FPZ52_RS06470	COG3421	Type III restriction
FPZ52_RS06575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPZ52_RS06585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPZ52_RS06590	COG3494	Protein of unknown function (DUF1009)
FPZ52_RS06595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPZ52_RS06610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPZ52_RS06615	COG0750	zinc metalloprotease
FPZ52_RS06620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FPZ52_RS06625	COG0575	Belongs to the CDS family
FPZ52_RS06630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FPZ52_RS06635	COG0233	cytoplasmic translational termination
FPZ52_RS06640	COG0528	UMP kinase activity
FPZ52_RS06645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FPZ52_RS06655	COG0747	negative chemotaxis
FPZ52_RS06660	COG0601	transmembrane transport
FPZ52_RS06665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS06680	COG2329	Antibiotic biosynthesis monooxygenase
FPZ52_RS06685	COG0488	(ABC) transporter
FPZ52_RS06705	COG0416	fatty acid biosynthetic process
FPZ52_RS06710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPZ52_RS06715	COG0776	regulation of translation
FPZ52_RS06735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPZ52_RS06740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FPZ52_RS06745	COG1472	Belongs to the glycosyl hydrolase 3 family
FPZ52_RS06755	COG0018	arginyl-trna synthetase
FPZ52_RS06760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FPZ52_RS06795	COG0501	Belongs to the peptidase M48B family
FPZ52_RS06810	COG0129	dihydroxy-acid dehydratase activity
FPZ52_RS06815	COG0800	Aldolase
FPZ52_RS06820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FPZ52_RS06825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPZ52_RS06840	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FPZ52_RS06870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPZ52_RS06880	COG0167	dihydroorotate dehydrogenase activity
FPZ52_RS06885	COG0543	2 iron, 2 sulfur cluster binding
FPZ52_RS06890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS06920	COG4974	Belongs to the 'phage' integrase family
FPZ52_RS06940	COG5285	phytanoyl-CoA dioxygenase
FPZ52_RS06955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FPZ52_RS06975	COG1278	Cold shock
FPZ52_RS06990	COG0556	nucleotide-excision repair
FPZ52_RS07030	COG3177	Filamentation induced by cAMP protein fic
FPZ52_RS07055	COG0517	IMP dehydrogenase activity
FPZ52_RS07070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPZ52_RS07080	COG1846	Transcriptional regulator
FPZ52_RS07100	COG2267	carboxylic ester hydrolase activity
FPZ52_RS07115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS07120	COG2274	protein secretion by the type I secretion system
FPZ52_RS07135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FPZ52_RS07140	COG1473	amidohydrolase
FPZ52_RS07155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPZ52_RS07165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPZ52_RS07175	COG0308	aminopeptidase N
FPZ52_RS07180	COG0693	protein deglycase activity
FPZ52_RS07195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPZ52_RS07235	COG3025	triphosphatase activity
FPZ52_RS07245	COG0006	proline dipeptidase activity
FPZ52_RS07275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FPZ52_RS07280	COG0849	cell division
FPZ52_RS07285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FPZ52_RS07290	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPZ52_RS07295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPZ52_RS07300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPZ52_RS07320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPZ52_RS07325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPZ52_RS07330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPZ52_RS07335	COG0768	penicillin binding
FPZ52_RS07345	COG0275	rRNA processing
FPZ52_RS07350	COG2001	Belongs to the MraZ family
FPZ52_RS07380	COG2084	Dehydrogenase
FPZ52_RS07385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPZ52_RS07390	COG1802	Transcriptional regulator
FPZ52_RS07405	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS07410	COG4172	Belongs to the ABC transporter superfamily
FPZ52_RS07420	COG0601	transmembrane transport
FPZ52_RS07425	COG0747	negative chemotaxis
FPZ52_RS07430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS07440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPZ52_RS07470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPZ52_RS07495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPZ52_RS07610	COG0667	Aldo Keto reductase
FPZ52_RS07615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPZ52_RS07650	COG0527	aspartate kinase activity
FPZ52_RS07655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPZ52_RS07670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPZ52_RS07685	COG0612	Peptidase, M16
FPZ52_RS07695	COG3346	SURF1 family
FPZ52_RS07705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FPZ52_RS07715	COG0109	protoheme IX farnesyltransferase activity
FPZ52_RS07725	COG0312	modulator of DNA gyrase
FPZ52_RS07730	COG0758	DNA mediated transformation
FPZ52_RS07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPZ52_RS07735	COG1754	DNA topoisomerase type I activity
FPZ52_RS07745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPZ52_RS07760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPZ52_RS07765	COG0037	tRNA processing
FPZ52_RS07775	COG2885	chlorophyll binding
FPZ52_RS07790	COG0848	biopolymer transport protein
FPZ52_RS07800	COG0824	Thioesterase
FPZ52_RS07810	COG2255	four-way junction helicase activity
FPZ52_RS07815	COG0632	four-way junction helicase activity
FPZ52_RS07830	COG2264	protein methyltransferase activity
FPZ52_RS07840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPZ52_RS07855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FPZ52_RS07860	COG3768	UPF0283 membrane protein
FPZ52_RS07870	COG3106	COG3106 Predicted ATPase
FPZ52_RS07875	COG0101	tRNA pseudouridine synthase activity
FPZ52_RS07890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPZ52_RS07905	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FPZ52_RS07915	COG1492	cobalamin metabolic process
FPZ52_RS07920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPZ52_RS07920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FPZ52_RS07930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FPZ52_RS07935	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FPZ52_RS07945	COG0012	GTP binding
FPZ52_RS07950	COG0110	maltose O-acetyltransferase activity
FPZ52_RS07955	COG1136	(ABC) transporter
FPZ52_RS07960	COG4591	ABC-type transport system involved in lipoprotein release permease component
FPZ52_RS07965	COG0442	prolyl-tRNA aminoacylation
FPZ52_RS07970	COG0628	permease
FPZ52_RS07985	COG0248	Ppx GppA phosphatase
FPZ52_RS07990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FPZ52_RS08005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPZ52_RS08005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPZ52_RS08015	COG4770	biotin carboxylase activity
FPZ52_RS08045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPZ52_RS08050	COG2814	Major facilitator Superfamily
FPZ52_RS08065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPZ52_RS08075	COG0330	HflC and HflK could
FPZ52_RS08080	COG0330	HflC and HflK could
FPZ52_RS08090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FPZ52_RS08105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FPZ52_RS08115	COG0504	CTP synthase activity
FPZ52_RS08140	COG0765	amino acid transport
FPZ52_RS08145	COG0174	glutamine synthetase
FPZ52_RS08150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FPZ52_RS08195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPZ52_RS08205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPZ52_RS08220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPZ52_RS08240	COG0768	penicillin binding
FPZ52_RS08245	COG0772	Belongs to the SEDS family
FPZ52_RS08255	COG1573	uracil-dna glycosylase
FPZ52_RS08285	COG0714	Associated with various cellular activities
FPZ52_RS08300	COG4774	siderophore transport
FPZ52_RS08310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FPZ52_RS08330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPZ52_RS08335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPZ52_RS08355	COG0154	amidase activity
FPZ52_RS08360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPZ52_RS08365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPZ52_RS08380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS08390	COG0183	Belongs to the thiolase family
FPZ52_RS08405	COG0590	tRNA wobble adenosine to inosine editing
FPZ52_RS08420	COG3853	Toxic anion resistance protein (TelA)
FPZ52_RS08445	COG1490	D-aminoacyl-tRNA deacylase activity
FPZ52_RS08455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FPZ52_RS08475	COG0784	Response regulator, receiver
FPZ52_RS08480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FPZ52_RS08490	COG4166	transmembrane transport
FPZ52_RS08495	COG0601	transmembrane transport
FPZ52_RS08500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS08505	COG4172	Belongs to the ABC transporter superfamily
FPZ52_RS08525	COG0339	signal peptide processing
FPZ52_RS08530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPZ52_RS08545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPZ52_RS08555	COG0606	chelatase, subunit chli
FPZ52_RS08565	COG0792	nuclease activity
FPZ52_RS08570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FPZ52_RS08580	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FPZ52_RS08585	COG0728	peptidoglycan biosynthetic process
FPZ52_RS08590	COG0180	Tryptophanyl-tRNA synthetase
FPZ52_RS08595	COG2514	catechol 2,3-dioxygenase activity
FPZ52_RS08615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FPZ52_RS08620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPZ52_RS08655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FPZ52_RS08660	COG1132	(ABC) transporter
FPZ52_RS08670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPZ52_RS08675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FPZ52_RS08680	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FPZ52_RS08695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPZ52_RS08705	COG2885	chlorophyll binding
FPZ52_RS08705	COG3047	cAMP biosynthetic process
FPZ52_RS08715	COG0314	molybdopterin synthase activity
FPZ52_RS08725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPZ52_RS08730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPZ52_RS08765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS08775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPZ52_RS08810	COG0546	phosphoglycolate phosphatase activity
FPZ52_RS08840	COG0071	Belongs to the small heat shock protein (HSP20) family
FPZ52_RS08845	COG3591	Belongs to the peptidase S1B family
FPZ52_RS08850	COG0247	lactate metabolic process
FPZ52_RS08855	COG0277	FAD linked oxidase domain protein
FPZ52_RS08860	COG0277	FAD linked oxidase domain protein
FPZ52_RS08890	COG0714	Associated with various cellular activities
FPZ52_RS08905	COG0789	Transcriptional regulator
FPZ52_RS08910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPZ52_RS08910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPZ52_RS08920	COG1131	(ABC) transporter
FPZ52_RS08925	COG2823	Periplasmic or secreted lipoprotein
FPZ52_RS08925	COG1652	LysM domain
FPZ52_RS08935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPZ52_RS08940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FPZ52_RS08945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPZ52_RS08945	COG2169	Transcriptional regulator
FPZ52_RS08950	COG2885	chlorophyll binding
FPZ52_RS08965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPZ52_RS08970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPZ52_RS08975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FPZ52_RS08980	COG0356	it plays a direct role in the translocation of protons across the membrane
FPZ52_RS09015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FPZ52_RS09025	COG0228	four-way junction DNA binding
FPZ52_RS09030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FPZ52_RS09045	COG0335	large ribosomal subunit rRNA binding
FPZ52_RS09050	COG0254	rRNA binding
FPZ52_RS09055	COG1192	Involved in chromosome partitioning
FPZ52_RS09060	COG0628	permease
FPZ52_RS09065	COG2358	TRAP transporter, solute receptor (TAXI family
FPZ52_RS09085	COG0322	excinuclease ABC activity
FPZ52_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS09095	COG0530	calcium, potassium:sodium antiporter activity
FPZ52_RS09120	COG3267	Type II secretory pathway component ExeA
FPZ52_RS09120	COG3409	Peptidoglycan-binding domain 1 protein
FPZ52_RS09150	COG0705	Rhomboid family
FPZ52_RS09155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPZ52_RS09160	COG2271	Major facilitator Superfamily
FPZ52_RS09165	COG2818	Glycosylase
FPZ52_RS09170	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FPZ52_RS09195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FPZ52_RS09215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPZ52_RS09235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPZ52_RS09250	COG0659	secondary active sulfate transmembrane transporter activity
FPZ52_RS09255	COG0489	protein tyrosine kinase activity
FPZ52_RS09270	COG3383	formate dehydrogenase (NAD+) activity
FPZ52_RS09270	COG0243	molybdopterin cofactor binding
FPZ52_RS09275	COG0437	4 iron, 4 sulfur cluster binding
FPZ52_RS09330	COG0582	viral genome integration into host DNA
FPZ52_RS09405	COG1132	(ABC) transporter
FPZ52_RS09410	COG0318	PFAM AMP-dependent synthetase and ligase
FPZ52_RS09420	COG0187	DNA topoisomerase II activity
FPZ52_RS09425	COG0534	Mate efflux family protein
FPZ52_RS09440	COG1846	Transcriptional regulator
FPZ52_RS09450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FPZ52_RS09460	COG1643	Atp-dependent helicase
FPZ52_RS09465	COG0584	glycerophosphoryl diester phosphodiesterase
FPZ52_RS09470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FPZ52_RS09475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPZ52_RS09485	COG0842	Transport permease protein
FPZ52_RS09495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPZ52_RS09500	COG1324	tolerance protein
FPZ52_RS09515	COG1872	DUF167
FPZ52_RS09520	COG0778	Nitroreductase
FPZ52_RS09535	COG0346	lactoylglutathione lyase activity
FPZ52_RS09550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FPZ52_RS09580	COG3852	Histidine kinase
FPZ52_RS09595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FPZ52_RS09600	COG0594	ribonuclease P activity
FPZ52_RS09605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPZ52_RS09610	COG0037	tRNA processing
FPZ52_RS09615	COG0706	membrane insertase activity
FPZ52_RS09630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FPZ52_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS09640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPZ52_RS09655	COG0765	amino acid transport
FPZ52_RS09660	COG4597	amino acid ABC transporter
FPZ52_RS09665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPZ52_RS09680	COG0564	pseudouridine synthase activity
FPZ52_RS09685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FPZ52_RS09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FPZ52_RS09715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FPZ52_RS09725	COG0420	3'-5' exonuclease activity
FPZ52_RS09835	COG2175	clavaminate synthase activity
FPZ52_RS09865	COG1609	Transcriptional regulator
FPZ52_RS09885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FPZ52_RS09885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPZ52_RS09890	COG0697	spore germination
FPZ52_RS09895	COG0741	lytic transglycosylase activity
FPZ52_RS09900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS09905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FPZ52_RS09915	COG2897	thiosulfate sulfurtransferase activity
FPZ52_RS09925	COG0004	ammonium transporteR
FPZ52_RS09930	COG0347	Belongs to the P(II) protein family
FPZ52_RS09940	COG2854	intermembrane phospholipid transfer
FPZ52_RS09945	COG2853	Lipoprotein
FPZ52_RS09965	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPZ52_RS09970	COG0678	peroxiredoxin activity
FPZ52_RS09970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FPZ52_RS09980	COG0742	ribosomal rna small subunit methyltransferase
FPZ52_RS09990	COG0024	Methionine aminopeptidase
FPZ52_RS09995	COG1546	Belongs to the CinA family
FPZ52_RS09995	COG1058	Belongs to the CinA family
FPZ52_RS10010	COG0583	DNA-binding transcription factor activity
FPZ52_RS10015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPZ52_RS10015	COG1902	pentaerythritol trinitrate reductase activity
FPZ52_RS10025	COG0129	dihydroxy-acid dehydratase activity
FPZ52_RS10035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FPZ52_RS10040	COG0285	dihydrofolate synthase activity
FPZ52_RS10050	COG2095	MarC family integral membrane protein
FPZ52_RS10055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FPZ52_RS10060	COG1295	ribonuclease BN
FPZ52_RS10085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPZ52_RS10085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPZ52_RS10100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FPZ52_RS10110	COG0612	Peptidase, M16
FPZ52_RS10115	COG0612	Peptidase, M16
FPZ52_RS10120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FPZ52_RS10160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FPZ52_RS10170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPZ52_RS10175	COG1335	isochorismatase
FPZ52_RS10180	COG1054	Belongs to the UPF0176 family
FPZ52_RS10185	COG1739	Uncharacterized protein family UPF0029
FPZ52_RS10195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPZ52_RS10205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPZ52_RS10225	COG1968	undecaprenyl-diphosphatase activity
FPZ52_RS10245	COG0137	argininosuccinate synthase activity
FPZ52_RS10270	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FPZ52_RS10275	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FPZ52_RS10280	COG1999	signal sequence binding
FPZ52_RS10300	COG3178	'Phosphotransferase
FPZ52_RS10305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPZ52_RS10310	COG2887	Belongs to the helicase family. UvrD subfamily
FPZ52_RS10330	COG5507	3-demethylubiquinone-9 3-methyltransferase
FPZ52_RS10340	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FPZ52_RS10345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FPZ52_RS10365	COG3030	protein affecting phage T7 exclusion by the F plasmid
FPZ52_RS10375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPZ52_RS10380	COG0237	dephospho-CoA kinase activity
FPZ52_RS10385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPZ52_RS10390	COG0424	maF-like protein
FPZ52_RS10395	COG1981	membrane
FPZ52_RS10400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FPZ52_RS10405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FPZ52_RS10410	COG0445	tRNA wobble uridine modification
FPZ52_RS10415	COG0357	Ribosomal RNA small subunit methyltransferase G
FPZ52_RS10430	COG2832	Protein of unknown function (DUF454)
FPZ52_RS10435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPZ52_RS10440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FPZ52_RS10445	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FPZ52_RS10450	COG1420	regulation of RNA biosynthetic process
FPZ52_RS10455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FPZ52_RS10460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FPZ52_RS10465	COG0280	phosphate acetyltransferase
FPZ52_RS10465	COG0281	malic enzyme
FPZ52_RS10470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPZ52_RS10475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPZ52_RS10485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FPZ52_RS10495	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FPZ52_RS10515	COG0514	ATP-dependent DNA helicase (RecQ)
FPZ52_RS10520	COG3022	response to hydroperoxide
FPZ52_RS10525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPZ52_RS10530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FPZ52_RS10585	COG3119	arylsulfatase activity
FPZ52_RS10595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPZ52_RS10600	COG0560	Phosphoserine phosphatase
FPZ52_RS10600	COG3830	Belongs to the UPF0237 family
FPZ52_RS10610	COG0557	exoribonuclease II activity
FPZ52_RS10615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPZ52_RS10635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPZ52_RS10640	COG1846	Transcriptional regulator
FPZ52_RS10645	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS10650	COG2081	HI0933 family
FPZ52_RS10655	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPZ52_RS10660	COG1722	exodeoxyribonuclease VII activity
FPZ52_RS10665	COG0142	geranyltranstransferase activity
FPZ52_RS10670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FPZ52_RS10725	COG0640	Transcriptional regulator
FPZ52_RS10745	COG4974	Belongs to the 'phage' integrase family
FPZ52_RS10750	COG0517	IMP dehydrogenase activity
FPZ52_RS10755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPZ52_RS10780	COG2171	N-acyltransferase activity
FPZ52_RS10800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FPZ52_RS10805	COG3474	cytochrome
FPZ52_RS10810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FPZ52_RS10820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPZ52_RS10845	COG1749	Flagellar hook protein flgE
FPZ52_RS10860	COG1706	bacterial-type flagellum-dependent cell motility
FPZ52_RS10875	COG1091	dTDP-4-dehydrorhamnose reductase activity
FPZ52_RS10880	COG1088	dTDP-glucose 4,6-dehydratase activity
FPZ52_RS10885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FPZ52_RS10895	COG2111	Na H antiporter
FPZ52_RS10895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPZ52_RS10900	COG2111	Na H antiporter
FPZ52_RS10905	COG1006	Multisubunit Na H antiporter MnhC subunit
FPZ52_RS10910	COG0651	ATP synthesis coupled electron transport
FPZ52_RS10915	COG1863	multisubunit Na H antiporter MnhE subunit
FPZ52_RS10920	COG2212	antiporter activity
FPZ52_RS10925	COG1320	monovalent cation:proton antiporter activity
FPZ52_RS10940	COG0546	phosphoglycolate phosphatase activity
FPZ52_RS10965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPZ52_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
FPZ52_RS10980	COG1522	sequence-specific DNA binding
FPZ52_RS10985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPZ52_RS10990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS10995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPZ52_RS11000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS11005	COG0589	response to stress
FPZ52_RS11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPZ52_RS11020	COG2423	ornithine cyclodeaminase activity
FPZ52_RS11025	COG0006	proline dipeptidase activity
FPZ52_RS11030	COG3608	succinylglutamate desuccinylase aspartoacylase
FPZ52_RS11050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FPZ52_RS11060	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPZ52_RS11075	COG3008	intermembrane lipid transfer
FPZ52_RS11080	COG2995	paraquat-inducible protein a
FPZ52_RS11090	COG1338	Plays a role in the flagellum-specific transport system
FPZ52_RS11095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPZ52_RS11105	COG1766	The M ring may be actively involved in energy transduction
FPZ52_RS11250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FPZ52_RS11285	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPZ52_RS11290	COG1684	flagellar biosynthetic protein fliR
FPZ52_RS11295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPZ52_RS11310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FPZ52_RS11320	COG4786	Flagellar basal body rod
FPZ52_RS11325	COG4786	Flagellar basal body rod
FPZ52_RS11330	COG1987	bacterial-type flagellum assembly
FPZ52_RS11335	COG1677	Flagellar hook-basal body complex protein FliE
FPZ52_RS11340	COG1558	bacterial-type flagellum-dependent cell motility
FPZ52_RS11360	COG5443	negative regulation of bacterial-type flagellum assembly
FPZ52_RS11370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPZ52_RS11390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FPZ52_RS11400	COG2226	methyltransferase
FPZ52_RS11405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPZ52_RS11415	COG0268	Binds directly to 16S ribosomal RNA
FPZ52_RS11420	COG1192	Involved in chromosome partitioning
FPZ52_RS11445	COG2133	pyrroloquinoline quinone binding
FPZ52_RS11475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS11495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPZ52_RS11530	COG1129	ABC transporter
FPZ52_RS11535	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS11540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPZ52_RS11545	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FPZ52_RS11550	COG1609	Transcriptional regulator
FPZ52_RS11565	COG1228	amidohydrolase
FPZ52_RS11590	COG0405	Gamma-glutamyltransferase
FPZ52_RS11600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPZ52_RS11600	COG0475	glutathione-regulated potassium exporter activity
FPZ52_RS11605	COG1741	Belongs to the pirin family
FPZ52_RS11620	COG0346	lactoylglutathione lyase activity
FPZ52_RS11625	COG1733	regulation of RNA biosynthetic process
FPZ52_RS11655	COG3273	potassium ion transport
FPZ52_RS11655	COG0471	metal ion transport
FPZ52_RS11760	COG1215	transferase activity, transferring glycosyl groups
FPZ52_RS11795	COG0438	transferase activity, transferring glycosyl groups
FPZ52_RS11850	COG2226	methyltransferase
FPZ52_RS11875	COG1609	Transcriptional regulator
FPZ52_RS11885	COG1082	Xylose isomerase domain protein TIM barrel
FPZ52_RS11890	COG1129	ABC transporter
FPZ52_RS11895	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS11935	COG1072	(Pantothenic acid kinase))
FPZ52_RS11965	COG0668	transmembrane transport
FPZ52_RS11985	COG0823	Involved in the tonB-independent uptake of proteins
FPZ52_RS11990	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS11995	COG1082	Xylose isomerase domain protein TIM barrel
FPZ52_RS12005	COG1653	transport
FPZ52_RS12010	COG3842	ATPase activity
FPZ52_RS12025	COG0656	L-ascorbic acid biosynthetic process
FPZ52_RS12040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS12045	COG2188	Transcriptional regulator
FPZ52_RS12050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS12060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS12065	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FPZ52_RS12085	COG0747	negative chemotaxis
FPZ52_RS12090	COG0601	transmembrane transport
FPZ52_RS12095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS12100	COG0444	Belongs to the ABC transporter superfamily
FPZ52_RS12105	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS12160	COG3119	arylsulfatase activity
FPZ52_RS12175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FPZ52_RS12180	COG0459	protein refolding
FPZ52_RS12185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS12200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPZ52_RS12215	COG1216	Glycosyl transferase, family 2
FPZ52_RS12215	COG0463	Glycosyl transferase, family 2
FPZ52_RS12225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS12230	COG4310	Domain of unknown function (DUF2172)
FPZ52_RS12235	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FPZ52_RS12255	COG2197	response regulator
FPZ52_RS12280	COG0438	transferase activity, transferring glycosyl groups
FPZ52_RS12300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPZ52_RS12305	COG1069	ribulokinase activity
FPZ52_RS12320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS12355	COG3938	Belongs to the proline racemase family
FPZ52_RS12360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPZ52_RS12365	COG3938	Belongs to the proline racemase family
FPZ52_RS12370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS12385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FPZ52_RS12390	COG1126	abc transporter atp-binding protein
FPZ52_RS12395	COG0765	amino acid transport
FPZ52_RS12405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPZ52_RS12415	COG0402	S-adenosylhomocysteine deaminase activity
FPZ52_RS12420	COG0402	S-adenosylhomocysteine deaminase activity
FPZ52_RS12425	COG0747	negative chemotaxis
FPZ52_RS12435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS12440	COG0444	Belongs to the ABC transporter superfamily
FPZ52_RS12445	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS12455	COG1070	Carbohydrate kinase
FPZ52_RS12465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FPZ52_RS12470	COG0667	Aldo Keto reductase
FPZ52_RS12475	COG2390	Transcriptional regulator
FPZ52_RS12480	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS12495	COG1011	Hydrolase
FPZ52_RS12505	COG3639	organic phosphonate transmembrane transporter activity
FPZ52_RS12520	COG1349	DNA-binding transcription factor activity
FPZ52_RS12530	COG2197	response regulator
FPZ52_RS12555	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS12565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS12570	COG0601	transmembrane transport
FPZ52_RS12585	COG0129	dihydroxy-acid dehydratase activity
FPZ52_RS12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS12595	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS12615	COG0601	transmembrane transport
FPZ52_RS12620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS12645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS12670	COG4166	transmembrane transport
FPZ52_RS12675	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FPZ52_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS12700	COG1177	transmembrane transport
FPZ52_RS12705	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPZ52_RS12710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FPZ52_RS12715	COG3842	ATPase activity
FPZ52_RS12740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPZ52_RS12745	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPZ52_RS12780	COG2274	protein secretion by the type I secretion system
FPZ52_RS12785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS12820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPZ52_RS12855	COG2814	Major facilitator Superfamily
FPZ52_RS12860	COG1473	amidohydrolase
FPZ52_RS12885	COG1178	ABC-type Fe3 transport system permease component
FPZ52_RS12895	COG2826	transposase and inactivated derivatives, IS30 family
FPZ52_RS12905	COG3683	transport system, periplasmic component
FPZ52_RS12910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FPZ52_RS12915	COG0523	cobalamin synthesis protein
FPZ52_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS12930	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FPZ52_RS12935	COG3806	Anti-sigma factor
FPZ52_RS12940	COG1595	DNA-templated transcription, initiation
FPZ52_RS12945	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FPZ52_RS12980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPZ52_RS13055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FPZ52_RS13080	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS13090	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS13100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPZ52_RS13115	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS13120	COG3962	Belongs to the TPP enzyme family
FPZ52_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS13135	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS13140	COG0747	negative chemotaxis
FPZ52_RS13150	COG0601	transmembrane transport
FPZ52_RS13155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS13165	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS13175	COG0583	DNA-binding transcription factor activity
FPZ52_RS13180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPZ52_RS13190	COG4829	muconolactone delta-isomerase
FPZ52_RS13200	COG2031	fatty acid transporter
FPZ52_RS13205	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPZ52_RS13205	COG0824	Thioesterase
FPZ52_RS13215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPZ52_RS13215	COG0473	3-isopropylmalate dehydrogenase activity
FPZ52_RS13220	COG2186	Transcriptional regulator
FPZ52_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS13250	COG1309	transcriptional regulator
FPZ52_RS13265	COG0402	S-adenosylhomocysteine deaminase activity
FPZ52_RS13275	COG4774	siderophore transport
FPZ52_RS13280	COG1120	ATPase activity
FPZ52_RS13285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS13290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS13305	COG0747	negative chemotaxis
FPZ52_RS13310	COG0246	Mannitol dehydrogenase
FPZ52_RS13315	COG1312	Catalyzes the dehydration of D-mannonate
FPZ52_RS13320	COG1802	Transcriptional regulator
FPZ52_RS13325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS13335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS13340	COG1063	alcohol dehydrogenase
FPZ52_RS13350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPZ52_RS13355	COG3842	ATPase activity
FPZ52_RS13360	COG0165	Argininosuccinate lyase
FPZ52_RS13395	COG1175	transmembrane transport
FPZ52_RS13400	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS13410	COG3842	ATPase activity
FPZ52_RS13415	COG1737	Transcriptional regulator
FPZ52_RS13425	COG1414	Transcriptional regulator
FPZ52_RS13445	COG0411	ABC transporter
FPZ52_RS13460	COG0640	Transcriptional regulator
FPZ52_RS13480	COG1757	Na H antiporter
FPZ52_RS13495	COG0517	IMP dehydrogenase activity
FPZ52_RS13495	COG0617	tRNA 3'-terminal CCA addition
FPZ52_RS13495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPZ52_RS13515	COG1475	DNA binding
FPZ52_RS13525	COG0583	DNA-binding transcription factor activity
FPZ52_RS13530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FPZ52_RS13540	COG2204	response regulator
FPZ52_RS13555	COG2391	methyltransferase activity
FPZ52_RS13565	COG1192	Involved in chromosome partitioning
FPZ52_RS13570	COG1475	DNA binding
FPZ52_RS13575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPZ52_RS13585	COG1473	amidohydrolase
FPZ52_RS13590	COG1957	nucleoside hydrolase
FPZ52_RS13595	COG0402	S-adenosylhomocysteine deaminase activity
FPZ52_RS13600	COG3842	ATPase activity
FPZ52_RS13610	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPZ52_RS13620	COG1363	Peptidase, m42
FPZ52_RS13625	COG1802	Transcriptional regulator
FPZ52_RS13630	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS13640	COG0601	transmembrane transport
FPZ52_RS13645	COG0747	negative chemotaxis
FPZ52_RS13655	COG1609	Transcriptional regulator
FPZ52_RS13660	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS13670	COG1653	transport
FPZ52_RS13675	COG1175	transmembrane transport
FPZ52_RS13680	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS13685	COG3842	ATPase activity
FPZ52_RS13690	COG2032	superoxide dismutase activity
FPZ52_RS13700	COG0747	negative chemotaxis
FPZ52_RS13705	COG0601	transmembrane transport
FPZ52_RS13715	COG3964	amidohydrolase
FPZ52_RS13740	COG1921	L-seryl-tRNASec selenium transferase activity
FPZ52_RS13750	COG4638	Rieske (2fe-2S)
FPZ52_RS13755	COG1902	pentaerythritol trinitrate reductase activity
FPZ52_RS13755	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPZ52_RS13775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FPZ52_RS13775	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPZ52_RS13825	COG2197	response regulator
FPZ52_RS13835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPZ52_RS13860	COG3842	ATPase activity
FPZ52_RS13865	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPZ52_RS13870	COG1177	transmembrane transport
FPZ52_RS13885	COG2081	HI0933 family
FPZ52_RS13890	COG1609	Transcriptional regulator
FPZ52_RS13915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPZ52_RS13920	COG0463	Glycosyl transferase, family 2
FPZ52_RS13920	COG1216	Glycosyl transferase, family 2
FPZ52_RS13925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPZ52_RS13940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPZ52_RS13950	COG1309	transcriptional regulator
FPZ52_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
FPZ52_RS13975	COG3119	arylsulfatase activity
FPZ52_RS13980	COG1309	transcriptional regulator
FPZ52_RS13995	COG4175	Glycine betaine
FPZ52_RS14000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPZ52_RS14005	COG0765	amino acid transport
FPZ52_RS14010	COG1126	abc transporter atp-binding protein
FPZ52_RS14050	COG1473	amidohydrolase
FPZ52_RS14055	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS14060	COG0444	Belongs to the ABC transporter superfamily
FPZ52_RS14070	COG0601	transmembrane transport
FPZ52_RS14080	COG0583	DNA-binding transcription factor activity
FPZ52_RS14125	COG0028	Belongs to the TPP enzyme family
FPZ52_RS14130	COG1609	Transcriptional regulator
FPZ52_RS14135	COG3250	beta-galactosidase activity
FPZ52_RS14145	COG1175	transmembrane transport
FPZ52_RS14150	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS14160	COG2233	PERMEase
FPZ52_RS14165	COG3591	Belongs to the peptidase S1B family
FPZ52_RS14165	COG1864	DNA RNA non-specific endonuclease
FPZ52_RS14185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FPZ52_RS14195	COG1271	oxidase subunit
FPZ52_RS14200	COG1294	oxidase, subunit
FPZ52_RS14210	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FPZ52_RS14215	COG0709	Synthesizes selenophosphate from selenide and ATP
FPZ52_RS14220	COG2169	Transcriptional regulator
FPZ52_RS14225	COG0747	negative chemotaxis
FPZ52_RS14235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS14240	COG4172	Belongs to the ABC transporter superfamily
FPZ52_RS14245	COG1486	melibiose metabolic process
FPZ52_RS14250	COG1486	melibiose metabolic process
FPZ52_RS14275	COG2046	Belongs to the sulfate adenylyltransferase family
FPZ52_RS14275	COG0529	Catalyzes the synthesis of activated sulfate
FPZ52_RS14280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FPZ52_RS14295	COG3842	ATPase activity
FPZ52_RS14300	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS14305	COG1175	transmembrane transport
FPZ52_RS14310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPZ52_RS14310	COG2207	Transcriptional regulator
FPZ52_RS14315	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS14335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS14340	COG1879	ABC-type sugar transport system periplasmic component
FPZ52_RS14345	COG1129	ABC transporter
FPZ52_RS14350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS14355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS14360	COG2186	Transcriptional regulator
FPZ52_RS14365	COG2814	Major facilitator Superfamily
FPZ52_RS14370	COG2951	lytic endotransglycosylase activity
FPZ52_RS14375	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS14380	COG1175	transmembrane transport
FPZ52_RS14395	COG3534	alpha-L-arabinofuranosidase
FPZ52_RS14405	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS14410	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS14415	COG1175	transmembrane transport
FPZ52_RS14430	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS14435	COG2188	Transcriptional regulator
FPZ52_RS14440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FPZ52_RS14445	COG1940	carbohydrate kinase activity
FPZ52_RS14450	COG3142	Participates in the control of copper homeostasis
FPZ52_RS14465	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS14475	COG3842	ATPase activity
FPZ52_RS14495	COG0251	oxidation-reduction process
FPZ52_RS14500	COG1737	Transcriptional regulator
FPZ52_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS14525	COG2885	chlorophyll binding
FPZ52_RS14530	COG0515	serine threonine protein kinase
FPZ52_RS14530	COG2815	serine threonine protein kinase
FPZ52_RS14535	COG0631	protein serine/threonine phosphatase activity
FPZ52_RS14550	COG2885	chlorophyll binding
FPZ52_RS14660	COG0583	DNA-binding transcription factor activity
FPZ52_RS14665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPZ52_RS14720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPZ52_RS14725	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPZ52_RS14730	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FPZ52_RS14745	COG2358	TRAP transporter, solute receptor (TAXI family
FPZ52_RS14760	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FPZ52_RS14770	COG1216	Glycosyl transferase, family 2
FPZ52_RS14785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPZ52_RS14795	COG1696	Membrane protein involved in D-alanine export
FPZ52_RS14825	COG0463	Glycosyl transferase, family 2
FPZ52_RS14845	COG1169	isochorismate synthase
FPZ52_RS14850	COG3433	isochorismatase activity
FPZ52_RS14850	COG1535	isochorismatase
FPZ52_RS14855	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS14865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS14875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS14880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPZ52_RS14890	COG1671	Belongs to the UPF0178 family
FPZ52_RS14905	COG4608	Belongs to the ABC transporter superfamily
FPZ52_RS14910	COG0747	negative chemotaxis
FPZ52_RS14915	COG0601	transmembrane transport
FPZ52_RS14920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS14925	COG0405	Gamma-glutamyltransferase
FPZ52_RS14935	COG0730	response to heat
FPZ52_RS14950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS14955	COG0601	transmembrane transport
FPZ52_RS14970	COG1454	alcohol dehydrogenase
FPZ52_RS14975	COG2186	Transcriptional regulator
FPZ52_RS14980	COG3395	kinase activity
FPZ52_RS14990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS15020	COG2205	protein histidine kinase activity
FPZ52_RS15025	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS15035	COG1192	Involved in chromosome partitioning
FPZ52_RS15045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FPZ52_RS15045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPZ52_RS15055	COG1021	2,3-dihydroxybenzoate-AMP ligase
FPZ52_RS15070	COG1653	transport
FPZ52_RS15075	COG1175	transmembrane transport
FPZ52_RS15080	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS15095	COG5441	Belongs to the UPF0261 family
FPZ52_RS15100	COG5564	TIM-barrel signal transduction protein
FPZ52_RS15110	COG5564	TIM-barrel signal transduction protein
FPZ52_RS15110	COG2204	response regulator
FPZ52_RS15115	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS15120	COG0662	Cupin 2, conserved barrel domain protein
FPZ52_RS15130	COG1120	ATPase activity
FPZ52_RS15135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS15140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS15145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPZ52_RS15150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPZ52_RS15155	COG1802	Transcriptional regulator
FPZ52_RS15160	COG0747	negative chemotaxis
FPZ52_RS15165	COG0601	transmembrane transport
FPZ52_RS15170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS15175	COG4172	Belongs to the ABC transporter superfamily
FPZ52_RS15180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPZ52_RS15190	COG3180	Ammonia monooxygenase
FPZ52_RS15205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPZ52_RS15210	COG3833	ABC-type maltose transport systems, permease component
FPZ52_RS15215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPZ52_RS15225	COG3842	ATPase activity
FPZ52_RS15260	COG0625	glutathione transferase activity
FPZ52_RS15275	COG3845	ABC transporter
FPZ52_RS15280	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS15285	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS15290	COG3214	Protein conserved in bacteria
FPZ52_RS15300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FPZ52_RS15305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FPZ52_RS15310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS15320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS15325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS15335	COG3250	beta-galactosidase activity
FPZ52_RS15340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPZ52_RS15355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPZ52_RS15375	COG3263	regulation of cellular component size
FPZ52_RS15405	COG1175	transmembrane transport
FPZ52_RS15415	COG3038	cytochrome b561
FPZ52_RS15435	COG1063	alcohol dehydrogenase
FPZ52_RS15485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPZ52_RS15505	COG4176	ABC-type proline glycine betaine transport system permease component
FPZ52_RS15520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPZ52_RS15530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS15535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS15545	COG1024	Enoyl-CoA hydratase
FPZ52_RS15545	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPZ52_RS15550	COG0183	Belongs to the thiolase family
FPZ52_RS15565	COG1309	transcriptional regulator
FPZ52_RS15575	COG0697	spore germination
FPZ52_RS15580	COG0436	Aminotransferase
FPZ52_RS15590	COG1487	ribonuclease activity
FPZ52_RS15595	COG1063	alcohol dehydrogenase
FPZ52_RS15600	COG0156	8-amino-7-oxononanoate synthase activity
FPZ52_RS15605	COG1396	sequence-specific DNA binding
FPZ52_RS15625	COG1477	protein flavinylation
FPZ52_RS15630	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FPZ52_RS15635	COG1805	sodium ion transport
FPZ52_RS15645	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FPZ52_RS15660	COG2197	response regulator
FPZ52_RS15675	COG0513	Belongs to the DEAD box helicase family
FPZ52_RS15685	COG3181	Tripartite tricarboxylate transporter family receptor
FPZ52_RS15700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPZ52_RS15735	COG2204	response regulator
FPZ52_RS15740	COG2205	protein histidine kinase activity
FPZ52_RS15765	COG0530	calcium, potassium:sodium antiporter activity
FPZ52_RS15780	COG0693	protein deglycase activity
FPZ52_RS15785	COG1879	ABC-type sugar transport system periplasmic component
FPZ52_RS15790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS15800	COG2186	Transcriptional regulator
FPZ52_RS15805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FPZ52_RS15825	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS15845	COG1802	Transcriptional regulator
FPZ52_RS15855	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS15940	COG2235	arginine
FPZ52_RS15945	COG0531	amino acid
FPZ52_RS15950	COG1288	antiporter activity
FPZ52_RS15960	COG1394	ATPase activity, coupled to movement of substances
FPZ52_RS15965	COG1269	ATP hydrolysis coupled proton transport
FPZ52_RS15985	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FPZ52_RS15995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS16000	COG1129	ABC transporter
FPZ52_RS16000	COG0842	Transport permease protein
FPZ52_RS16005	COG0842	Transport permease protein
FPZ52_RS16060	COG1748	Saccharopine dehydrogenase
FPZ52_RS16080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPZ52_RS16085	COG1960	acyl-CoA dehydrogenase activity
FPZ52_RS16090	COG0583	DNA-binding transcription factor activity
FPZ52_RS16100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPZ52_RS16110	COG1376	ErfK ybiS ycfS ynhG family protein
FPZ52_RS16115	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS16125	COG3842	ATPase activity
FPZ52_RS16140	COG1653	transport
FPZ52_RS16145	COG1609	Transcriptional regulator
FPZ52_RS16165	COG0348	domain, Protein
FPZ52_RS16170	COG2010	Cytochrome c
FPZ52_RS16190	COG1960	acyl-CoA dehydrogenase activity
FPZ52_RS16215	COG1522	sequence-specific DNA binding
FPZ52_RS16225	COG2011	ABC-type metal ion transport system permease component
FPZ52_RS16230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FPZ52_RS16240	COG0010	Belongs to the arginase family
FPZ52_RS16245	COG2124	cytochrome p450
FPZ52_RS16260	COG0811	peptide transport
FPZ52_RS16280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPZ52_RS16285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FPZ52_RS16290	COG1137	ATPase activity
FPZ52_RS16310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPZ52_RS16320	COG2954	triphosphatase activity
FPZ52_RS16325	COG2951	lytic endotransglycosylase activity
FPZ52_RS16335	COG1051	belongs to the nudix hydrolase family
FPZ52_RS16340	COG0793	Belongs to the peptidase S41A family
FPZ52_RS16350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FPZ52_RS16355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPZ52_RS16360	COG0799	negative regulation of ribosome biogenesis
FPZ52_RS16365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPZ52_RS16375	COG0066	3-isopropylmalate dehydratase activity
FPZ52_RS16385	COG0473	3-isopropylmalate dehydrogenase activity
FPZ52_RS16390	COG0697	spore germination
FPZ52_RS16395	COG1414	Transcriptional regulator
FPZ52_RS16405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPZ52_RS16410	COG0183	Belongs to the thiolase family
FPZ52_RS16425	COG5507	3-demethylubiquinone-9 3-methyltransferase
FPZ52_RS16440	COG0583	DNA-binding transcription factor activity
FPZ52_RS16455	COG1902	pentaerythritol trinitrate reductase activity
FPZ52_RS16465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPZ52_RS16485	COG1349	DNA-binding transcription factor activity
FPZ52_RS16490	COG1192	Involved in chromosome partitioning
FPZ52_RS16505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPZ52_RS16510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FPZ52_RS16520	COG3811	Belongs to the UPF0386 family
FPZ52_RS16565	COG1136	(ABC) transporter
FPZ52_RS16570	COG0577	efflux transmembrane transporter activity
FPZ52_RS16585	COG0693	protein deglycase activity
FPZ52_RS16595	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS16605	COG1609	Transcriptional regulator
FPZ52_RS16630	COG2252	PERMEase
FPZ52_RS16640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FPZ52_RS16650	COG3842	ATPase activity
FPZ52_RS16655	COG1840	ABC-type Fe3 transport system, periplasmic component
FPZ52_RS16660	COG1178	ABC-type Fe3 transport system permease component
FPZ52_RS16715	COG0174	glutamine synthetase
FPZ52_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS16760	COG1063	alcohol dehydrogenase
FPZ52_RS16765	COG1522	sequence-specific DNA binding
FPZ52_RS16770	COG0517	IMP dehydrogenase activity
FPZ52_RS16775	COG4974	Belongs to the 'phage' integrase family
FPZ52_RS16780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FPZ52_RS16785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPZ52_RS16845	COG0583	DNA-binding transcription factor activity
FPZ52_RS16850	COG0625	glutathione transferase activity
FPZ52_RS16860	COG1942	4-Oxalocrotonate Tautomerase
FPZ52_RS16865	COG2070	2-Nitropropane dioxygenase
FPZ52_RS16880	COG0517	IMP dehydrogenase activity
FPZ52_RS16890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPZ52_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS16935	COG1802	Transcriptional regulator
FPZ52_RS16955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPZ52_RS16960	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FPZ52_RS16965	COG2301	Belongs to the HpcH HpaI aldolase family
FPZ52_RS16985	COG4221	oxidoreductase activity
FPZ52_RS17010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPZ52_RS17020	COG0583	DNA-binding transcription factor activity
FPZ52_RS17130	COG4977	sequence-specific DNA binding
FPZ52_RS17145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS17155	COG0656	L-ascorbic acid biosynthetic process
FPZ52_RS17165	COG1121	(ABC) transporter
FPZ52_RS17185	COG0667	Aldo Keto reductase
FPZ52_RS17225	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FPZ52_RS17230	COG3639	organic phosphonate transmembrane transporter activity
FPZ52_RS17235	COG3639	organic phosphonate transmembrane transporter activity
FPZ52_RS17245	COG1609	Transcriptional regulator
FPZ52_RS17250	COG3624	Phosphonate C-P lyase system protein PhnG
FPZ52_RS17260	COG3626	phosphonate metabolism
FPZ52_RS17270	COG3627	carbon phosphorus lyase activity
FPZ52_RS17275	COG4107	phosphonate C-P lyase system protein PhnK
FPZ52_RS17280	COG4778	phosphonate C-P lyase system protein PhnL
FPZ52_RS17290	COG3454	Phosphonate metabolism
FPZ52_RS17295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPZ52_RS17300	COG0494	nUDIX hydrolase
FPZ52_RS17310	COG0494	nUDIX hydrolase
FPZ52_RS17315	COG0617	tRNA 3'-terminal CCA addition
FPZ52_RS17325	COG1132	(ABC) transporter
FPZ52_RS17365	COG1040	competence protein
FPZ52_RS17370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FPZ52_RS17375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPZ52_RS17380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPZ52_RS17395	COG0779	Required for maturation of 30S ribosomal subunits
FPZ52_RS17410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FPZ52_RS17415	COG0494	nUDIX hydrolase
FPZ52_RS17420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FPZ52_RS17425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPZ52_RS17430	COG0653	protein targeting
FPZ52_RS17440	COG2003	Belongs to the UPF0758 family
FPZ52_RS17450	COG0443	Heat shock 70 kDa protein
FPZ52_RS17465	COG1218	3'(2'),5'-bisphosphate nucleotidase
FPZ52_RS17470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FPZ52_RS17475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPZ52_RS17485	COG1215	transferase activity, transferring glycosyl groups
FPZ52_RS17500	COG1012	belongs to the aldehyde dehydrogenase family
FPZ52_RS17505	COG0583	DNA-binding transcription factor activity
FPZ52_RS17515	COG0745	RESPONSE REGULATOR receiver
FPZ52_RS17525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPZ52_RS17535	COG0573	inorganic phosphate transmembrane transporter activity
FPZ52_RS17545	COG4136	ATPase activity
FPZ52_RS17550	COG4135	transport system, permease component
FPZ52_RS17555	COG4134	Bacterial extracellular solute-binding protein
FPZ52_RS17560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPZ52_RS17600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPZ52_RS17605	COG3386	PFAM SMP-30 Gluconolaconase
FPZ52_RS17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS17620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS17630	COG1012	belongs to the aldehyde dehydrogenase family
FPZ52_RS17635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FPZ52_RS17640	COG1349	DNA-binding transcription factor activity
FPZ52_RS17645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPZ52_RS17680	COG1175	transmembrane transport
FPZ52_RS17685	COG0395	ABC-type sugar transport system, permease component
FPZ52_RS17690	COG3842	ATPase activity
FPZ52_RS17700	COG3254	rhamnose metabolic process
FPZ52_RS17715	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS17730	COG0277	FAD linked oxidase domain protein
FPZ52_RS17735	COG2186	Transcriptional regulator
FPZ52_RS17740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS17745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPZ52_RS17755	COG1802	Transcriptional regulator
FPZ52_RS17765	COG1802	Transcriptional regulator
FPZ52_RS17770	COG2721	sulfolactate sulfo-lyase activity
FPZ52_RS17775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPZ52_RS17790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPZ52_RS17795	COG1522	sequence-specific DNA binding
FPZ52_RS17800	COG1609	Transcriptional regulator
FPZ52_RS17810	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS17815	COG1129	ABC transporter
FPZ52_RS17820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS17825	COG1879	ABC-type sugar transport system periplasmic component
FPZ52_RS17830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPZ52_RS17835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPZ52_RS17840	COG3181	Tripartite tricarboxylate transporter family receptor
FPZ52_RS17855	COG1309	transcriptional regulator
FPZ52_RS17875	COG4948	Mandelate Racemase Muconate Lactonizing
FPZ52_RS17905	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS17915	COG2183	response to ionizing radiation
FPZ52_RS17925	COG2943	transferase activity, transferring hexosyl groups
FPZ52_RS17930	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FPZ52_RS17935	COG0737	Belongs to the 5'-nucleotidase family
FPZ52_RS17945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPZ52_RS17955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPZ52_RS17970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FPZ52_RS17975	COG3842	ATPase activity
FPZ52_RS17980	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPZ52_RS17985	COG1177	transmembrane transport
FPZ52_RS17990	COG0174	glutamine synthetase
FPZ52_RS17995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPZ52_RS18000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPZ52_RS18000	COG0519	Catalyzes the synthesis of GMP from XMP
FPZ52_RS18005	COG0628	permease
FPZ52_RS18015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS18025	COG0673	inositol 2-dehydrogenase activity
FPZ52_RS18045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FPZ52_RS18055	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS18060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPZ52_RS18065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPZ52_RS18070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPZ52_RS18075	COG2186	Transcriptional regulator
FPZ52_RS18080	COG0277	FAD linked oxidase domain protein
FPZ52_RS18085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPZ52_RS18090	COG2084	Dehydrogenase
FPZ52_RS18095	COG0129	dihydroxy-acid dehydratase activity
FPZ52_RS18100	COG4993	Dehydrogenase
FPZ52_RS18120	COG1116	anion transmembrane transporter activity
FPZ52_RS18155	COG1858	cytochrome C peroxidase
FPZ52_RS18180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPZ52_RS18210	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FPZ52_RS18215	COG0667	Aldo Keto reductase
FPZ52_RS18220	COG2207	Transcriptional regulator
FPZ52_RS18225	COG2855	membrane
FPZ52_RS18230	COG0583	DNA-binding transcription factor activity
FPZ52_RS18235	COG0850	regulation of cytokinetic process
FPZ52_RS18240	COG2894	cell division
FPZ52_RS18245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FPZ52_RS18265	COG1538	Outer membrane efflux protein
FPZ52_RS18270	COG2274	protein secretion by the type I secretion system
FPZ52_RS18300	COG1596	polysaccharide export
FPZ52_RS18320	COG2273	Hydrolase Family 16
FPZ52_RS18325	COG1215	transferase activity, transferring glycosyl groups
FPZ52_RS18340	COG1215	transferase activity, transferring glycosyl groups
FPZ52_RS18345	COG1215	transferase activity, transferring glycosyl groups
FPZ52_RS18355	COG1253	flavin adenine dinucleotide binding
FPZ52_RS18365	COG3273	potassium ion transport
FPZ52_RS18365	COG0471	metal ion transport
FPZ52_RS18385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FPZ52_RS18390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FPZ52_RS18400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPZ52_RS18405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPZ52_RS18410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPZ52_RS18430	COG1309	transcriptional regulator
FPZ52_RS18440	COG0493	'glutamate synthase
FPZ52_RS18445	COG0527	aspartate kinase activity
FPZ52_RS18450	COG1917	Cupin 2, conserved barrel domain protein
FPZ52_RS18455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FPZ52_RS18465	COG1846	Transcriptional regulator
FPZ52_RS18500	COG1126	abc transporter atp-binding protein
FPZ52_RS18525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPZ52_RS18530	COG0402	S-adenosylhomocysteine deaminase activity
FPZ52_RS18535	COG0583	DNA-binding transcription factor activity
FPZ52_RS18540	COG2354	Protein conserved in bacteria
FPZ52_RS18565	COG1780	Probably involved in ribonucleotide reductase function
FPZ52_RS18570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPZ52_RS18585	COG1132	(ABC) transporter
FPZ52_RS18600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPZ52_RS18605	COG0747	negative chemotaxis
FPZ52_RS18615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPZ52_RS18645	COG4604	ABC transporter, ATP-binding protein
FPZ52_RS18650	COG4605	iron ion homeostasis
FPZ52_RS18655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPZ52_RS18660	COG4607	ABC-type enterochelin transport system periplasmic component
FPZ52_RS18665	COG0431	NADPH-dependent FMN reductase
FPZ52_RS18675	COG0798	PFAM Bile acid sodium symporter
FPZ52_RS18695	COG1121	(ABC) transporter
FPZ52_RS18700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPZ52_RS18705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPZ52_RS18715	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FPZ52_RS18735	COG0789	Transcriptional regulator
FPZ52_RS18740	COG0251	oxidation-reduction process
FPZ52_RS18745	COG4952	isomerase
FPZ52_RS18750	COG3347	Dehydrogenase
FPZ52_RS18750	COG1028	Short-chain dehydrogenase reductase Sdr
FPZ52_RS18765	COG1129	ABC transporter
FPZ52_RS18770	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS18775	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPZ52_RS18780	COG3254	rhamnose metabolic process
FPZ52_RS18795	COG1136	(ABC) transporter
FPZ52_RS18815	COG3064	Membrane