locus-tag	class	description
G8D25_RS00065	ENOG4108UKI	Enoyl-CoA hydratase
G8D25_RS00075	ENOG4105DTD	Dehydrogenase
G8D25_RS00115	ENOG4105DSQ	Nitric oxide reductase
G8D25_RS00130	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
G8D25_RS00135	ENOG4108VYJ	response regulator receiver protein
G8D25_RS00140	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G8D25_RS00155	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G8D25_RS00170	ENOG4105BZU	Histidine kinase
G8D25_RS00190	ENOG4108V1U	phospholipid-binding protein
G8D25_RS00225	ENOG4108IV0	ABC, transporter
G8D25_RS00230	ENOG4105C0Z	ABC transporter
G8D25_RS00235	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G8D25_RS00240	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D25_RS00250	ENOG4105BZU	Histidine kinase
G8D25_RS00260	ENOG41090T1	Membrane
G8D25_RS00265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS00275	ENOG4105CSH	Transporter
G8D25_RS00280	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G8D25_RS00300	ENOG4105VEQ	Cold shock protein
G8D25_RS00310	ENOG4105C7N	Xanthine uracil vitamin C permease
G8D25_RS00320	ENOG4105BZU	Histidine kinase
G8D25_RS00340	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D25_RS00355	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS00360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS00430	ENOG4108KTQ	Methyltransferase
G8D25_RS00460	ENOG4108VN5	Inherit from COG: PepSY-associated TM helix
G8D25_RS00480	ENOG4108IJF	Heavy metal efflux pump, CzcA
G8D25_RS00485	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
G8D25_RS00505	ENOG4108IXY	short-chain dehydrogenase reductase
G8D25_RS00525	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS00530	ENOG4105E9Z	Nad-dependent epimerase dehydratase
G8D25_RS00535	ENOG4108HWW	ABC transporter
G8D25_RS00545	ENOG4105DFW	ABC transporter
G8D25_RS00550	ENOG4105TW1	Carbohydrate-selective porin OprB
G8D25_RS00605	ENOG4105KD7	acetyltransferase
G8D25_RS00645	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
G8D25_RS00655	ENOG4105GTN	ParB Domain Protein Nuclease
G8D25_RS00660	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS00665	ENOG4105CTX	dehydratase
G8D25_RS00670	ENOG4105DJB	Major Facilitator Superfamily
G8D25_RS00675	ENOG4105CNV	Aldolase
G8D25_RS00680	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D25_RS00730	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8D25_RS00735	ENOG4107Z5Z	endoribonuclease L-PSP
G8D25_RS00740	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G8D25_RS00745	ENOG4105CSH	Transporter
G8D25_RS00750	ENOG4108IMY	Transcriptional regulator
G8D25_RS00765	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS00770	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G8D25_RS00785	ENOG4108SC4	)-transporter
G8D25_RS00790	ENOG4108Z9W	Outer membrane porin
G8D25_RS00795	ENOG4105ETT	transcriptional Regulator, LysR family
G8D25_RS00815	ENOG4105C28	cystathionine
G8D25_RS00825	ENOG4105CH6	catalase
G8D25_RS00850	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS00860	ENOG4106PMH	Extracellular solute-binding protein family 3
G8D25_RS00875	ENOG4105CSP	Major Facilitator Superfamily
G8D25_RS00910	ENOG4105CCU	oxidase (Subunit III)
G8D25_RS00920	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G8D25_RS00925	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G8D25_RS00945	ENOG4105C01	Dihydroxy-acid dehydratase
G8D25_RS00950	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
G8D25_RS00965	ENOG4105CHC	glucokinase (EC 2.7.1.2)
G8D25_RS00975	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D25_RS00980	ENOG4105DHQ	Histidine kinase
G8D25_RS01000	ENOG4105CSH	Transporter
G8D25_RS01005	ENOG4108UB3	Thiamine monophosphate
G8D25_RS01070	ENOG4105CHR	reductase
G8D25_RS01080	ENOG4107QWG	2-Nitropropane dioxygenase
G8D25_RS01090	ENOG4105U3E	Transcriptional regulator
G8D25_RS01100	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS01110	ENOG4105BZS	acriflavin resistance protein
G8D25_RS01130	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8D25_RS01135	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8D25_RS01180	ENOG4105W1Y	Transcriptional regulator
G8D25_RS01220	ENOG4107XCH	Cyclase family
G8D25_RS01245	ENOG41061RM	osmotically inducible lipoprotein
G8D25_RS01250	ENOG4105BZU	Histidine kinase
G8D25_RS01255	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
G8D25_RS01260	ENOG4105CZE	histidine utilization repressor
G8D25_RS01285	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
G8D25_RS01290	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G8D25_RS01295	ENOG4108ZC9	flagellar basal-body rod protein flgc
G8D25_RS01300	ENOG4105W00	Flagellar hook capping protein
G8D25_RS01305	ENOG4105BZE	flagellar hook protein, FlgE
G8D25_RS01310	ENOG4108KPB	Flagellar basal-body rod protein FlgF
G8D25_RS01315	ENOG4105CGA	flagellar basal-body rod protein FlgG
G8D25_RS01330	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G8D25_RS01335	ENOG4105E1Q	flagellar hook-associated protein
G8D25_RS01340	ENOG4105DTJ	flagellar hook-associated protein
G8D25_RS01350	ENOG4107T3I	fad-binding protein
G8D25_RS01360	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G8D25_RS01370	ENOG4105CN7	Flagellar biosynthetic protein FliP
G8D25_RS01380	ENOG4105DD5	Flagellar motor switch protein
G8D25_RS01385	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G8D25_RS01395	ENOG4105BZU	Histidine kinase
G8D25_RS01400	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS01405	ENOG4105I03	Flagellin
G8D25_RS01405	ENOG4105I03	Flagellin
G8D25_RS01410	ENOG4105DTS	flagellar hook-associated
G8D25_RS01415	ENOG4105MQ3	flagellar protein FliS
G8D25_RS01425	ENOG4105K56	Transcriptional regulator
G8D25_RS01445	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G8D25_RS01450	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G8D25_RS01455	ENOG4105W2B	Flagellar assembly protein
G8D25_RS01460	ENOG4108JIR	Flagellum-specific ATP synthase
G8D25_RS01520	ENOG4107RCI	amp-dependent synthetase and ligase
G8D25_RS01565	ENOG4105EU0	Major facilitator Superfamily
G8D25_RS01595	ENOG4105CIF	Ornithine Cyclodeaminase
G8D25_RS01600	ENOG4105DJU	Siderophore biosynthesis protein
G8D25_RS01610	ENOG4105DBM	Siderophore biosynthesis protein
G8D25_RS01615	ENOG4105DUU	IucA IucC family protein
G8D25_RS01625	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G8D25_RS01720	ENOG4108QZZ	filamentous hemagglutinin
G8D25_RS01725	ENOG4105D5K	Hemolysin activator protein
G8D25_RS01755	ENOG4107YHX	fad dependent oxidoreductase
G8D25_RS01815	ENOG4105BZU	Histidine kinase
G8D25_RS01850	ENOG4108SGR	YheO domain-containing protein
G8D25_RS01860	ENOG4105KME	endoribonuclease L-psp
G8D25_RS01865	ENOG4105DUM	transcriptional regulator, lysR family
G8D25_RS01905	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS01915	ENOG4105FDP	GntR family transcriptional regulator
G8D25_RS01965	ENOG4105DQQ	Major facilitator superfamily MFS_1
G8D25_RS01975	ENOG4108IUE	nitrate reductase beta subunit
G8D25_RS01985	ENOG41076YT	nitrate reductase, gamma subunit
G8D25_RS01990	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
G8D25_RS01995	ENOG4105BZU	Histidine kinase
G8D25_RS02000	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS02005	ENOG4106HNH	Acyl-transferase
G8D25_RS02035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G8D25_RS02075	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
G8D25_RS02085	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G8D25_RS02095	ENOG4107QKZ	Ompa motb domain protein
G8D25_RS02110	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G8D25_RS02140	ENOG4105VV6	START domain-containing protein
G8D25_RS02145	ENOG4105E1F	short-chain dehydrogenase reductase
G8D25_RS02180	ENOG4105DWV	Homoserine O-trans-acetylase
G8D25_RS02185	ENOG4105CB2	alcohol dehydrogenase
G8D25_RS02190	ENOG4108IXY	short-chain dehydrogenase reductase
G8D25_RS02195	ENOG4108IG5	Transcriptional regulator
G8D25_RS02240	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G8D25_RS02245	ENOG4105F7P	transcriptional regulator AsnC family
G8D25_RS02250	ENOG4105MVH	Clavaminate synthase
G8D25_RS02275	ENOG4105CNA	YD repeat protein
G8D25_RS02340	ENOG4105EJC	lysr family transcriptional regulator
G8D25_RS02345	ENOG4105EMU	Dehydrogenase
G8D25_RS02355	ENOG4105ENX	hydrolase
G8D25_RS02380	ENOG410642W	LysR family Transcriptional regulator
G8D25_RS02435	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
G8D25_RS02440	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
G8D25_RS02445	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
G8D25_RS02450	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
G8D25_RS02500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D25_RS02505	ENOG4108RYK	Nad-dependent epimerase dehydratase
G8D25_RS02515	ENOG4105KVH	Transcriptional regulator
G8D25_RS02545	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G8D25_RS02550	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G8D25_RS02560	ENOG4107QRP	cobalamin biosynthesis protein CobW
G8D25_RS02565	ENOG4105E4R	Precorrin-3B C17-methyltransferase
G8D25_RS02570	ENOG4108P62	biosynthesis protein (CbiG)
G8D25_RS02580	ENOG4105DVK	Precorrin-2 c20-methyltransferase
G8D25_RS02595	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G8D25_RS02610	ENOG4105NZG	Ferredoxin
G8D25_RS02620	ENOG4105CDA	abc transporter atp-binding protein
G8D25_RS02625	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS02630	ENOG4105EZ7	amino acid ABC transporter
G8D25_RS02635	ENOG4108HW3	(ABC) transporter
G8D25_RS02640	ENOG4105D16	lipopolysaccharide heptosyltransferase i
G8D25_RS02665	ENOG4108UYU	AsnC family transcriptional regulator
G8D25_RS02675	ENOG4105E39	Enoyl-CoA hydratase
G8D25_RS02680	ENOG4105E39	Enoyl-CoA hydratase
G8D25_RS02685	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D25_RS02690	ENOG4105C26	Dehydrogenase
G8D25_RS02695	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8D25_RS02700	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS02705	ENOG4108ZX5	transcriptional regulator
G8D25_RS02735	ENOG4107QUT	magnesium and cobalt transport protein CorA
G8D25_RS02740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8D25_RS02745	ENOG4105DJ2	Major Facilitator Superfamily
G8D25_RS02770	ENOG4106B0W	Curli production assembly transport component CsgG
G8D25_RS02780	ENOG4107Y60	(LipO)protein
G8D25_RS02790	ENOG4105DZ2	Transcriptional regulator
G8D25_RS02840	ENOG4105JQN	Transcriptional regulator
G8D25_RS02845	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS02875	ENOG4108S2Y	peptide Chain Release factor
G8D25_RS02910	ENOG4105C0Z	ABC transporter
G8D25_RS02915	ENOG4108IV0	ABC, transporter
G8D25_RS02970	ENOG41079HR	Phosphate-Selective Porin O and P
G8D25_RS03080	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D25_RS03095	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D25_RS03110	ENOG4105F32	YngK protein
G8D25_RS03120	ENOG4108ZG0	Ompa motb domain protein
G8D25_RS03185	ENOG4105EVZ	LysR family transcriptional regulator
G8D25_RS03215	ENOG4105F4P	)-transporter
G8D25_RS03240	ENOG4108Z4U	Ferredoxin
G8D25_RS03250	ENOG4105DUM	transcriptional regulator, lysR family
G8D25_RS03255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G8D25_RS03260	ENOG4107RCV	ABC transporter, permease
G8D25_RS03270	ENOG4105C4Y	ABC transporter
G8D25_RS03290	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G8D25_RS03300	ENOG4105BZU	Histidine kinase
G8D25_RS03320	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS03325	ENOG4105BZS	acriflavin resistance protein
G8D25_RS03330	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8D25_RS03335	ENOG4105FDR	Membrane
G8D25_RS03355	ENOG4107RSM	transcriptional regulator
G8D25_RS03365	ENOG4105I7M	spermidine synthase
G8D25_RS03380	ENOG4105DJB	Major Facilitator Superfamily
G8D25_RS03390	ENOG4105CTX	dehydratase
G8D25_RS03395	ENOG4105E9Z	Nad-dependent epimerase dehydratase
G8D25_RS03410	ENOG4105DPW	Major facilitator superfamily MFS_1
G8D25_RS03440	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS03445	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
G8D25_RS03490	ENOG4108SF5	RNA Polymerase
G8D25_RS03500	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS03505	ENOG4108STX	response regulator
G8D25_RS03540	ENOG4105VS8	Flagellar biosynthetic protein fliq
G8D25_RS03580	ENOG4107Y59	type iii secretion
G8D25_RS03595	ENOG4108JIR	Flagellum-specific ATP synthase
G8D25_RS03720	ENOG4105C0W	non-ribosomal peptide synthetase
G8D25_RS03725	ENOG4107SQU	synthase
G8D25_RS03735	ENOG4107QKG	PfaD family
G8D25_RS03760	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
G8D25_RS03765	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G8D25_RS03805	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D25_RS03820	ENOG4107R4J	Chloride channel
G8D25_RS03825	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8D25_RS03865	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
G8D25_RS03905	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G8D25_RS03945	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G8D25_RS03950	ENOG4107WZ3	Transferase
G8D25_RS03955	ENOG4105D3Q	Sugar transferase
G8D25_RS03975	ENOG4108UW5	maltose o-acetyltransferase
G8D25_RS04075	ENOG4105BZ1	(ABC) transporter
G8D25_RS04125	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
G8D25_RS04135	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS04160	ENOG4105C26	Dehydrogenase
G8D25_RS04165	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D25_RS04170	ENOG4108JQ6	ABC transporter
G8D25_RS04175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS04185	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
G8D25_RS04190	ENOG4105CJP	fad dependent oxidoreductase
G8D25_RS04200	ENOG4105C26	Dehydrogenase
G8D25_RS04210	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
G8D25_RS04215	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G8D25_RS04220	ENOG4108RYR	transcriptional regulator AsnC family
G8D25_RS04235	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G8D25_RS04285	ENOG4105CVI	Transcriptional regulator
G8D25_RS04310	ENOG4109045	doxx family
G8D25_RS04360	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G8D25_RS04365	ENOG4105BZU	Histidine kinase
G8D25_RS04375	ENOG4105VEQ	Cold shock protein
G8D25_RS04385	ENOG4105C26	Dehydrogenase
G8D25_RS04390	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G8D25_RS04420	ENOG4105D9R	oxidoreductase
G8D25_RS04430	ENOG4108KPW	sugar kinase
G8D25_RS04440	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G8D25_RS04460	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS04480	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
G8D25_RS04545	ENOG4105D5K	Hemolysin activator protein
G8D25_RS04660	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS04665	ENOG4105BZU	Histidine kinase
G8D25_RS04690	ENOG4105CMR	udp-glucose 4-epimerase
G8D25_RS04695	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D25_RS04705	ENOG4108K4C	ec 3.1.3.12
G8D25_RS04710	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
G8D25_RS04715	ENOG4105K56	Transcriptional regulator
G8D25_RS04720	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G8D25_RS04735	ENOG4105CVE	Lytic murein transglycosylase
G8D25_RS04740	ENOG4105CBN	LysR family transcriptional regulator
G8D25_RS04750	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G8D25_RS04760	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS04765	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
G8D25_RS04770	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
G8D25_RS04780	ENOG4108UXE	Protein tyrosine phosphatase
G8D25_RS04790	ENOG41085FC	arsR family transcriptional regulator
G8D25_RS04800	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS04805	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS04820	ENOG4105E0C	molybdate abc transporter
G8D25_RS04825	ENOG4108IJ6	ABC transporter
G8D25_RS04830	ENOG4105F4R	Transcriptional regulator mode
G8D25_RS04840	ENOG4105BZU	Histidine kinase
G8D25_RS04865	ENOG4105XDF	Protein of unknown function (DUF1272)
G8D25_RS04880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8D25_RS04885	ENOG4105EB3	Histidine kinase
G8D25_RS04910	ENOG4105EE5	Membrane protein terC
G8D25_RS04915	ENOG4105CA0	peroxidase
G8D25_RS04945	ENOG4105BZU	Histidine kinase
G8D25_RS04975	ENOG4105C6Z	Gluconate
G8D25_RS04980	ENOG4108UHU	Aldolase
G8D25_RS04990	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS05005	ENOG4105E0F	Histidine kinase
G8D25_RS05025	ENOG4105BZS	acriflavin resistance protein
G8D25_RS05030	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS05040	ENOG4105BZU	Histidine kinase
G8D25_RS05055	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8D25_RS05060	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8D25_RS05065	ENOG4105BZU	Histidine kinase
G8D25_RS05070	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS05085	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G8D25_RS05095	ENOG4105C39	capsular polysaccharide phosphotransferase
G8D25_RS05100	ENOG4107QJQ	Mate efflux family protein
G8D25_RS05140	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G8D25_RS05145	ENOG4105WZK	nitrite reductase NADPH small subunit
G8D25_RS05150	ENOG4107QZF	nitrite reductase NADPH large subunit
G8D25_RS05155	ENOG4107RNU	major facilitator superfamily MFS_1
G8D25_RS05160	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G8D25_RS05190	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G8D25_RS05210	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
G8D25_RS05215	ENOG4105JSC	dimethylmenaquinone methyltransferase
G8D25_RS05225	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D25_RS05245	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
G8D25_RS05260	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G8D25_RS05270	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G8D25_RS05290	ENOG4105CHR	reductase
G8D25_RS05310	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8D25_RS05315	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8D25_RS05330	ENOG4105KME	endoribonuclease L-psp
G8D25_RS05365	ENOG4105CAF	HipA N-terminal domain protein
G8D25_RS05415	ENOG4105HF0	Membrane
G8D25_RS05420	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8D25_RS05430	ENOG4105RQF	LysR family Transcriptional regulator
G8D25_RS05435	ENOG4105EJ9	Membrane
G8D25_RS05460	ENOG4105C4R	Atp-dependent dna helicase
G8D25_RS05475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8D25_RS05485	ENOG4106855	Competence protein
G8D25_RS05520	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS05525	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G8D25_RS05545	ENOG4105Z6B	inner membrane protein yjfl
G8D25_RS05550	ENOG4105CP9	extracellular ligand-binding receptor
G8D25_RS05565	ENOG4105C0Z	ABC transporter
G8D25_RS05570	ENOG4108IV0	ABC, transporter
G8D25_RS05615	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G8D25_RS05620	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
G8D25_RS05645	ENOG4105GVF	(ABC) transporter
G8D25_RS05655	ENOG4108VIA	integral membrane protein
G8D25_RS05680	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D25_RS05690	ENOG4105FZW	flagellar biosynthesis regulator FlhF
G8D25_RS05695	ENOG4105D7B	Flagellar biosynthesis protein flha
G8D25_RS05700	ENOG4105D00	flagellar biosynthetic protein flhB
G8D25_RS05705	ENOG4108W9H	Tetr family transcriptional regulator
G8D25_RS05720	ENOG4107S9B	Shikimate dehydrogenase
G8D25_RS05725	ENOG4108Z9W	Outer membrane porin
G8D25_RS05730	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G8D25_RS05740	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G8D25_RS05745	ENOG4108VYJ	response regulator receiver protein
G8D25_RS05760	ENOG4105BZU	Histidine kinase
G8D25_RS05765	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS05770	ENOG4108V3W	Chemotaxis protein, CheW
G8D25_RS05775	ENOG4105CBS	Chea signal transduction histidine kinase
G8D25_RS05780	ENOG4108VYJ	response regulator receiver protein
G8D25_RS05785	ENOG4105ER2	Ompa motb domain protein
G8D25_RS05790	ENOG4107RD7	Flagellar Motor Protein, MotA
G8D25_RS05795	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
G8D25_RS05820	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D25_RS05825	ENOG4105EB3	Histidine kinase
G8D25_RS05875	ENOG4105E0F	Histidine kinase
G8D25_RS05880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8D25_RS05885	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS05900	ENOG4105F11	amine oxidase
G8D25_RS05905	ENOG4105CPN	adenine deaminase
G8D25_RS05910	ENOG4105DU0	nucleoside hydrolase
G8D25_RS05930	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
G8D25_RS05960	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G8D25_RS06025	ENOG4105GR3	Histidine kinase
G8D25_RS06030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D25_RS06060	ENOG4105EMU	Dehydrogenase
G8D25_RS06100	ENOG4105KME	endoribonuclease L-psp
G8D25_RS06105	ENOG4105C85	amino acid
G8D25_RS06120	ENOG41065HY	1,4-beta-cellobiosidase
G8D25_RS06140	ENOG4105EW9	transcriptional regulator AsnC family
G8D25_RS06165	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G8D25_RS06190	ENOG41067HZ	cytochrome C, class I
G8D25_RS06200	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G8D25_RS06210	ENOG4108JSS	Haloalkane dehalogenase
G8D25_RS06215	ENOG41090U3	tautomerase
G8D25_RS06220	ENOG4105EGI	Transcriptional regulator
G8D25_RS06235	ENOG41064T2	transcriptional regulator, lysR family
G8D25_RS06265	ENOG41061MD	high-affinity nickel-transporter
G8D25_RS06295	ENOG4108YZA	Nitrogen regulatory protein pii
G8D25_RS06305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8D25_RS06325	ENOG4108RYK	Nad-dependent epimerase dehydratase
G8D25_RS06335	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D25_RS06345	ENOG4105F7F	Chaperone
G8D25_RS06355	ENOG4105BZU	Histidine kinase
G8D25_RS06380	ENOG4105D64	Mechanosensitive ion channel
G8D25_RS06410	ENOG410802X	bacteriophage n4 adsorption protein b
G8D25_RS06430	ENOG4108JQ1	Dehydrogenase
G8D25_RS06440	ENOG4105K59	histidine triad (HIT) protein
G8D25_RS06495	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G8D25_RS06500	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G8D25_RS06530	ENOG4107QWB	Ornithine cyclodeaminase
G8D25_RS06535	ENOG4105EW9	transcriptional regulator AsnC family
G8D25_RS06540	ENOG4105EAB	amino acid AbC transporter
G8D25_RS06545	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS06550	ENOG4105CDA	abc transporter atp-binding protein
G8D25_RS06620	ENOG4108JJA	ABC, transporter
G8D25_RS06645	ENOG4106S2D	Transcriptional regulator
G8D25_RS06745	ENOG4105CHR	reductase
G8D25_RS06775	ENOG4105DJ4	phosphatidylserine decarboxylase
G8D25_RS06865	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G8D25_RS06870	ENOG4105BZU	Histidine kinase
G8D25_RS06875	ENOG4105BZU	Histidine kinase
G8D25_RS06885	ENOG4105CE1	Ferrous iron transport protein b
G8D25_RS06905	ENOG41090R7	Ferric uptake
G8D25_RS06910	ENOG4108JU3	Alkyl hydroperoxide reductase
G8D25_RS06920	ENOG4105D05	Receptor
G8D25_RS06925	ENOG4106QJH	hemin transport protein
G8D25_RS06940	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
G8D25_RS06945	ENOG4105CG3	alpha amylase, catalytic region
G8D25_RS06960	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
G8D25_RS06965	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
G8D25_RS07050	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
G8D25_RS07055	ENOG4108ZT1	Transcriptional regulator
G8D25_RS07075	ENOG4105BZU	Histidine kinase
G8D25_RS07080	ENOG4105EAB	amino acid AbC transporter
G8D25_RS07085	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS07090	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS07105	ENOG4105FYV	Amp nucleosidase
G8D25_RS07125	ENOG4108S4H	thioesterase Superfamily protein
G8D25_RS07130	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G8D25_RS07160	ENOG4108VCT	Sulfite exporter TauE/SafE
G8D25_RS07170	ENOG4105EQ2	LysR family Transcriptional regulator
G8D25_RS07175	ENOG4107SET	aldo keto reductase
G8D25_RS07180	ENOG4105C2C	drug resistance transporter, Bcr CflA
G8D25_RS07185	ENOG4105CPF	Cell wall formation (By similarity)
G8D25_RS07250	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
G8D25_RS07265	ENOG4105WQT	MbtH domain protein
G8D25_RS07270	ENOG4107QJQ	Mate efflux family protein
G8D25_RS07340	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G8D25_RS07375	ENOG4108VAU	general secretion pathway protein G
G8D25_RS07385	ENOG4107QHF	type ii secretion system protein e
G8D25_RS07410	ENOG4105E4G	Type IV pilus
G8D25_RS07420	ENOG4106855	Competence protein
G8D25_RS07535	ENOG4105W08	virulence gene repressor rsal
G8D25_RS07540	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
G8D25_RS07545	ENOG4108JU7	Transcriptional regulator
G8D25_RS07555	ENOG4105BZN	citrate synthase
G8D25_RS07585	ENOG4105CHH	sulfate transporter
G8D25_RS07590	ENOG41077A9	carbonic anhydrase
G8D25_RS07595	ENOG4105F8C	transglutaminase domain-containing protein
G8D25_RS07605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G8D25_RS07620	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G8D25_RS07665	ENOG4108M0I	Transcriptional regulator
G8D25_RS07715	ENOG4105VUH	addiction module killer protein
G8D25_RS07720	ENOG4105YES	addiction module antidote protein
G8D25_RS07725	ENOG4105CSH	Transporter
G8D25_RS07735	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
G8D25_RS07950	ENOG41082BM	Transcriptional regulator, arsr family
G8D25_RS07955	ENOG4105JQN	Transcriptional regulator
G8D25_RS07965	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D25_RS07985	ENOG4108YQE	rare lipoprotein a
G8D25_RS07990	ENOG4108K3A	Glutathione S-transferase
G8D25_RS07995	ENOG4105KVH	Transcriptional regulator
G8D25_RS08010	ENOG4105N14	lysine exporter protein LysE YggA
G8D25_RS08025	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G8D25_RS08035	ENOG4105C5W	Aldolase
G8D25_RS08040	ENOG41084KP	4-oxalocrotonate tautomerase
G8D25_RS08045	ENOG4105MP9	class II Aldolase
G8D25_RS08050	ENOG4105CBP	Major Facilitator
G8D25_RS08055	ENOG4105EGI	Transcriptional regulator
G8D25_RS08090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G8D25_RS08095	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D25_RS08120	ENOG4105CX6	glutaminyL-tRNA synthetase
G8D25_RS08150	ENOG4108VWS	Yaeq family
G8D25_RS08155	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8D25_RS08165	ENOG4108NH8	Cation transport protein
G8D25_RS08175	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS08180	ENOG4105K63	Thioredoxin
G8D25_RS08190	ENOG4105Y3Q	hemerythrin-like, metal-binding protein
G8D25_RS08195	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
G8D25_RS08200	ENOG4105CUZ	uba thif-type nad fad binding protein
G8D25_RS08205	ENOG41066T0	asmA family
G8D25_RS08220	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G8D25_RS08225	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G8D25_RS08235	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G8D25_RS08250	ENOG4105F7P	transcriptional regulator AsnC family
G8D25_RS08255	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
G8D25_RS08265	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
G8D25_RS08275	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS08280	ENOG4105C7N	Xanthine uracil vitamin C permease
G8D25_RS08285	ENOG4105D3R	alkyl hydroperoxide reductase
G8D25_RS08290	ENOG4105TNS	Conserved Protein
G8D25_RS08310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G8D25_RS08320	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G8D25_RS08330	ENOG4107T8P	acyl-Coa dehydrogenase
G8D25_RS08345	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8D25_RS08355	ENOG4105CUC	YeeE YedE family protein
G8D25_RS08365	ENOG4105UFD	tol-pal system protein YbgF
G8D25_RS08370	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G8D25_RS08375	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G8D25_RS08385	ENOG4105M8F	Biopolymer transport protein exbD tolR
G8D25_RS08390	ENOG4105E02	MotA TolQ exbB proton channel
G8D25_RS08395	ENOG4107YD3	Thioesterase
G8D25_RS08400	ENOG4105EMU	Dehydrogenase
G8D25_RS08405	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G8D25_RS08410	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G8D25_RS08475	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G8D25_RS08485	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G8D25_RS08490	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G8D25_RS08495	ENOG4107YIM	Involved in the transcription termination process (By similarity)
G8D25_RS08505	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
G8D25_RS08510	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
G8D25_RS08515	ENOG4105C26	Dehydrogenase
G8D25_RS08545	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G8D25_RS08550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D25_RS08555	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G8D25_RS08565	ENOG4105KRS	Proteinase inhibitor
G8D25_RS08570	ENOG4108IG5	Transcriptional regulator
G8D25_RS08575	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G8D25_RS08580	ENOG4105VFE	sira family
G8D25_RS08595	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G8D25_RS08600	ENOG4105D16	lipopolysaccharide heptosyltransferase i
G8D25_RS08605	ENOG4107QKV	phosphomannomutase
G8D25_RS08640	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G8D25_RS08655	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G8D25_RS08660	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G8D25_RS08670	ENOG4105CD3	dihydroorotase
G8D25_RS08675	ENOG4105CXT	aspartate transcarbamylase
G8D25_RS08680	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
G8D25_RS08685	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G8D25_RS08690	ENOG4108UJU	UPF0301 protein
G8D25_RS08695	ENOG4105I08	Pseudouridine synthase
G8D25_RS08700	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G8D25_RS08710	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS08715	ENOG4108V3W	Chemotaxis protein, CheW
G8D25_RS08720	ENOG4105M3Z	response regulator
G8D25_RS08725	ENOG4108UNF	response regulator
G8D25_RS08730	ENOG4105VCQ	rubredoxin
G8D25_RS08735	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G8D25_RS08745	ENOG4108V0P	LemA family
G8D25_RS08860	ENOG4108M3P	Membrane
G8D25_RS08865	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G8D25_RS08870	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G8D25_RS08875	ENOG4105CMM	transposase
G8D25_RS08880	ENOG4105R8A	Heat shock protein
G8D25_RS08890	ENOG4105DH7	May be involved in recombination (By similarity)
G8D25_RS09005	ENOG4107QPD	alcohol dehydrogenase
G8D25_RS09010	ENOG4105C4W	S-formylglutathione hydrolase
G8D25_RS09025	ENOG4105F1S	paraquat-inducible protein a
G8D25_RS09030	ENOG4105DY2	Paraquat-inducible protein b
G8D25_RS09040	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8D25_RS09095	ENOG41061H0	Monooxygenase
G8D25_RS09105	ENOG4105BZU	Histidine kinase
G8D25_RS09110	ENOG4105CI2	imidazolone-5-propionate hydrolase
G8D25_RS09115	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
G8D25_RS09135	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
G8D25_RS09140	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
G8D25_RS09150	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G8D25_RS09155	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G8D25_RS09160	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G8D25_RS09165	ENOG4105C8V	SAICAR synthetase
G8D25_RS09175	ENOG4105CA9	Pyruvate kinase
G8D25_RS09180	ENOG4105BZA	Phosphoglycerate kinase
G8D25_RS09185	ENOG4105FR1	rard protein
G8D25_RS09200	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G8D25_RS09210	ENOG4105XA0	heptosyltransferase ii
G8D25_RS09220	ENOG4105DNZ	Alpha Beta Hydrolase
G8D25_RS09230	ENOG4105ERG	peptidase m48, ste24p
G8D25_RS09235	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G8D25_RS09335	ENOG4105KHS	type IV fimbrial pilin protein
G8D25_RS09340	ENOG4105KHS	type IV fimbrial pilin protein
G8D25_RS09345	ENOG4108ZCF	integral membrane protein
G8D25_RS09350	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G8D25_RS09355	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G8D25_RS09365	ENOG4108004	Modulates RecA activity (By similarity)
G8D25_RS09370	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G8D25_RS09380	ENOG4105DHQ	Histidine kinase
G8D25_RS09390	ENOG4105CSH	Transporter
G8D25_RS09465	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G8D25_RS09470	ENOG4105EXG	Transcriptional regulator
G8D25_RS09475	ENOG4105EUB	pirin domain protein
G8D25_RS09480	ENOG4105E27	serine threonine protein kinase
G8D25_RS09485	ENOG4105C1J	atp-dependent rna helicase
G8D25_RS09495	ENOG4107QPN	acyl-Coa dehydrogenase
G8D25_RS09500	ENOG4105CHR	reductase
G8D25_RS09510	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS09525	ENOG4105BZ8	glutamate synthase
G8D25_RS09535	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G8D25_RS09540	ENOG4105C9A	Phoh family
G8D25_RS09545	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G8D25_RS09555	ENOG4108JU5	Magnesium and cobalt efflux protein
G8D25_RS09560	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G8D25_RS09565	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
G8D25_RS09575	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G8D25_RS09580	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
G8D25_RS09585	ENOG4105E9Q	Acyl-transferase
G8D25_RS09595	ENOG4108UYE	Lactoylglutathione lyase
G8D25_RS09600	ENOG4108594	Permease of the drug metabolite transporter
G8D25_RS09605	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G8D25_RS09610	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G8D25_RS09615	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G8D25_RS09620	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G8D25_RS09625	ENOG4105EHM	Aminoglycoside phosphotransferase
G8D25_RS09640	ENOG4108S0S	Nucleotidyl transferase
G8D25_RS09645	ENOG4105BZU	Histidine kinase
G8D25_RS09655	ENOG4107RAQ	aminopeptidase
G8D25_RS09660	ENOG4105D0A	hydroxylase
G8D25_RS09665	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8D25_RS09670	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8D25_RS09675	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G8D25_RS09680	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G8D25_RS09685	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G8D25_RS09695	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G8D25_RS09700	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G8D25_RS09715	ENOG4108V1U	phospholipid-binding protein
G8D25_RS09720	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G8D25_RS09725	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G8D25_RS09730	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G8D25_RS09735	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
G8D25_RS09750	ENOG4108UJD	30S ribosomal protein S9
G8D25_RS09755	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G8D25_RS09775	ENOG4105EKE	dihydroorotase
G8D25_RS09785	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D25_RS09790	ENOG4105E7A	Glutamine amidotransferase
G8D25_RS09795	ENOG4105CDA	abc transporter atp-binding protein
G8D25_RS09800	ENOG4105DRP	amino acid AbC transporter
G8D25_RS09805	ENOG4105EAD	ABC transporter
G8D25_RS09810	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS09820	ENOG4105D82	Glutamate dehydrogenase
G8D25_RS09830	ENOG4108JJ7	ABC transporter
G8D25_RS09835	ENOG4105NAU	thioesterase Superfamily protein
G8D25_RS09840	ENOG4105E39	Enoyl-CoA hydratase
G8D25_RS09845	ENOG4105CHU	acetyl-coa acetyltransferase
G8D25_RS09855	ENOG4105CSU	acyl-Coa dehydrogenase
G8D25_RS09865	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
G8D25_RS09870	ENOG4105DZQ	phospholipase D Transphosphatidylase
G8D25_RS09875	ENOG4105X23	Endonuclease Exonuclease phosphatase
G8D25_RS09880	ENOG4108TIT	dATP pyrophosphohydrolase
G8D25_RS09890	ENOG4105C9M	aspartyl-trna synthetase
G8D25_RS09915	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G8D25_RS09930	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G8D25_RS09955	ENOG4105W39	Membrane
G8D25_RS09975	ENOG4105C7B	Threonine dehydratase
G8D25_RS09980	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G8D25_RS10010	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS10015	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
G8D25_RS10030	ENOG4105MD1	YeeE YedE family protein
G8D25_RS10045	ENOG4105C2D	reductase
G8D25_RS10060	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G8D25_RS10085	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G8D25_RS10125	ENOG4108UUM	single-stranded DNA-binding protein
G8D25_RS10130	ENOG4107RDB	Major Facilitator
G8D25_RS10135	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G8D25_RS10145	ENOG4105EAM	Na Pi-cotransporter
G8D25_RS10155	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G8D25_RS10160	ENOG4107R7Y	intracellular protease Pfpi family
G8D25_RS10175	ENOG4105C2X	Arabinose 5-phosphate isomerase
G8D25_RS10180	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
G8D25_RS10195	ENOG4108IUZ	ABC transporter
G8D25_RS10200	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D25_RS10205	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
G8D25_RS10210	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G8D25_RS10215	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G8D25_RS10225	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G8D25_RS10235	ENOG4105CEN	a g-specific adenine glycosylase
G8D25_RS10245	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G8D25_RS10255	ENOG4105QVB	outer membrane lipoprotein LolB
G8D25_RS10260	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G8D25_RS10270	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G8D25_RS10275	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G8D25_RS10280	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G8D25_RS10290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G8D25_RS10295	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G8D25_RS10300	ENOG4106H78	methyltransferase
G8D25_RS10320	ENOG4108RXX	maleylacetoacetate isomerase
G8D25_RS10335	ENOG4105I5W	Transporter
G8D25_RS10345	ENOG4105D7T	ABC transporter
G8D25_RS10350	ENOG4108MTB	glycosyl transferase family
G8D25_RS10355	ENOG4105EUB	pirin domain protein
G8D25_RS10365	ENOG4105BZU	Histidine kinase
G8D25_RS10370	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D25_RS10375	ENOG4108ZX6	Electron transport protein SCO1 SenC
G8D25_RS10380	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G8D25_RS10385	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
G8D25_RS10405	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
G8D25_RS10415	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
G8D25_RS10425	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G8D25_RS10430	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G8D25_RS10440	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G8D25_RS10445	ENOG4105MJ2	Competence protein
G8D25_RS10455	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G8D25_RS10460	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
G8D25_RS10465	ENOG4105VW4	glutaredoxin 3
G8D25_RS10470	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
G8D25_RS10475	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G8D25_RS10485	ENOG4105D06	uba thif-type nad fad binding protein
G8D25_RS10490	ENOG4108UQY	Iron-storage protein
G8D25_RS10500	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G8D25_RS10505	ENOG41080Z8	PHOSPHOCARRIER protein
G8D25_RS10515	ENOG4105D7Z	glutathione synthase
G8D25_RS10525	ENOG4105BZU	Histidine kinase
G8D25_RS10530	ENOG4108YZA	Nitrogen regulatory protein pii
G8D25_RS10540	ENOG4105W0Z	cytoplasmic protein
G8D25_RS10550	ENOG4105C0P	Mg chelatase subunit ChlI
G8D25_RS10570	ENOG4108UVJ	appr-1-p processing domain protein
G8D25_RS10580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS10590	ENOG4105CK2	sodium dicarboxylate symporter
G8D25_RS10595	ENOG4105NZG	Ferredoxin
G8D25_RS10600	ENOG4105DHZ	alpha beta
G8D25_RS10605	ENOG4105DZ1	carboxypeptidase
G8D25_RS10610	ENOG4108Z43	UPF0250 protein
G8D25_RS10615	ENOG4105ETT	transcriptional Regulator, LysR family
G8D25_RS10625	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G8D25_RS10630	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G8D25_RS10675	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G8D25_RS10680	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G8D25_RS10690	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G8D25_RS10750	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G8D25_RS10765	ENOG4105C3R	Methionine synthase
G8D25_RS10770	ENOG4105C3R	Methionine synthase
G8D25_RS10785	ENOG4108NEV	two component transcriptional regulator, LytTR family
G8D25_RS10810	ENOG4105C75	arginyL-tRNA synthetase
G8D25_RS10825	ENOG4105EMU	Dehydrogenase
G8D25_RS10835	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
G8D25_RS10845	ENOG4108Z6Z	Transcriptional regulator
G8D25_RS10850	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS10855	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
G8D25_RS10860	ENOG41077A9	carbonic anhydrase
G8D25_RS10865	ENOG4105CHU	acetyl-coa acetyltransferase
G8D25_RS10870	ENOG4107FW0	short-chain dehydrogenase reductase
G8D25_RS10875	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS10890	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
G8D25_RS10895	ENOG4105K5B	UPF0225 protein
G8D25_RS10900	ENOG4107QX3	carboxylase
G8D25_RS10910	ENOG4108IPT	Naphthoate synthase
G8D25_RS10915	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G8D25_RS10940	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
G8D25_RS10945	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G8D25_RS10970	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
G8D25_RS10995	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G8D25_RS11010	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D25_RS11015	ENOG4105D5P	Methylmalonyl-coA mutase
G8D25_RS11055	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8D25_RS11065	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
G8D25_RS11070	ENOG410756H	nucleotidyltransferase
G8D25_RS11075	ENOG4105E0Y	RtcB Protein
G8D25_RS11085	ENOG4105CYB	regulatoR
G8D25_RS11100	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
G8D25_RS11125	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G8D25_RS11130	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G8D25_RS11140	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G8D25_RS11145	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
G8D25_RS11170	ENOG4105BZ8	glutamate synthase
G8D25_RS11185	ENOG4107QWP	ABC-2 type transporter
G8D25_RS11190	ENOG4105CJ1	ABC, transporter
G8D25_RS11195	ENOG4105D0S	secretion protein (HlyD
G8D25_RS11210	ENOG4105DND	Transcriptional regulator
G8D25_RS11215	ENOG4105C8Y	Acetylornithine aminotransferase
G8D25_RS11240	ENOG4105EYM	Major Facilitator superfamily
G8D25_RS11245	ENOG4105D0M	Protease HtpX homolog
G8D25_RS11250	ENOG4108KTG	Membrane protein, drug metabolite transporter
G8D25_RS11255	ENOG4105FG0	Nitroreductase
G8D25_RS11275	ENOG4107S90	membrAne
G8D25_RS11295	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G8D25_RS11300	ENOG4108Z12	YiaAB two helix domain-containing protein
G8D25_RS11305	ENOG4105CGK	Exodeoxyribonuclease III
G8D25_RS11310	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G8D25_RS11315	ENOG4105CSR	polyphosphate kinase 2
G8D25_RS11320	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G8D25_RS11335	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G8D25_RS11355	ENOG4105W87	Cbs domain
G8D25_RS11400	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS11405	ENOG4105CSU	acyl-Coa dehydrogenase
G8D25_RS11445	ENOG4105EA8	2-Nitropropane dioxygenase
G8D25_RS11450	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G8D25_RS11465	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G8D25_RS11475	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
G8D25_RS11485	ENOG4105DWF	phosphomethylpyrimidine kinase
G8D25_RS11500	ENOG4105G6Z	alkaline phosphatase
G8D25_RS11505	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G8D25_RS11510	ENOG41086DT	Membrane protein of unknown function
G8D25_RS11515	ENOG4105SYT	Methylenetetrahydrofolate reductase
G8D25_RS11525	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G8D25_RS11530	ENOG4107SC1	transglycosylase
G8D25_RS11540	ENOG4108RXX	maleylacetoacetate isomerase
G8D25_RS11545	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G8D25_RS11550	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS11560	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G8D25_RS11590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS11595	ENOG4105ES5	Histidine kinase
G8D25_RS11605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G8D25_RS11610	ENOG4105D0M	Protease HtpX homolog
G8D25_RS11620	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G8D25_RS11630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G8D25_RS11635	ENOG4108WZM	domain protein
G8D25_RS11640	ENOG4105C79	DNA protecting protein DprA
G8D25_RS11650	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G8D25_RS11655	ENOG4105CC0	LysR family Transcriptional regulator
G8D25_RS11660	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS11665	ENOG4105CNI	cell division protein FtsW
G8D25_RS11670	ENOG4105CJN	penicillin-binding protein
G8D25_RS11680	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G8D25_RS11690	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8D25_RS11695	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G8D25_RS11710	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8D25_RS11720	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D25_RS11725	ENOG4105DR4	Methyltransferase
G8D25_RS11745	ENOG4105CKI	cobalamin synthesis protein
G8D25_RS11765	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G8D25_RS11770	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G8D25_RS11780	ENOG4108UYB	regulatoR
G8D25_RS11810	ENOG4108WQI	RNA Polymerase
G8D25_RS11815	ENOG4105CAS	nag kinase
G8D25_RS11825	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
G8D25_RS11850	ENOG4108JPW	Aminotransferase
G8D25_RS11855	ENOG4105C26	Dehydrogenase
G8D25_RS11860	ENOG4105DWV	Homoserine O-trans-acetylase
G8D25_RS11880	ENOG4105VCD	cytoplasmic protein
G8D25_RS11885	ENOG4105D22	carbon starvation protein
G8D25_RS11900	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G8D25_RS11910	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D25_RS11915	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G8D25_RS11920	ENOG4108M3J	Dehydrogenase
G8D25_RS11925	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G8D25_RS11930	ENOG4105DC8	reductase
G8D25_RS11940	ENOG4108IG5	Transcriptional regulator
G8D25_RS11945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8D25_RS11955	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS11995	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G8D25_RS12000	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G8D25_RS12005	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G8D25_RS12010	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G8D25_RS12020	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G8D25_RS12025	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G8D25_RS12030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D25_RS12160	ENOG4105FFC	UPF0187 protein
G8D25_RS12175	ENOG4105EAB	amino acid AbC transporter
G8D25_RS12180	ENOG4105E5Q	amino acid AbC transporter
G8D25_RS12185	ENOG4105CDA	abc transporter atp-binding protein
G8D25_RS12190	ENOG4105CJP	fad dependent oxidoreductase
G8D25_RS12205	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D25_RS12210	ENOG4105DHQ	Histidine kinase
G8D25_RS12225	ENOG4105FCW	Major Facilitator superfamily
G8D25_RS12240	ENOG4105KPV	Transcriptional regulator
G8D25_RS12265	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D25_RS12270	ENOG4105D2X	ABC transporter substrate-binding protein
G8D25_RS12285	ENOG4105D3W	isochorismatase
G8D25_RS12290	ENOG41068CG	regulatoR
G8D25_RS12295	ENOG4105BZU	Histidine kinase
G8D25_RS12300	ENOG4105D01	(LipO)protein
G8D25_RS12305	ENOG4105C08	Histidine kinase
G8D25_RS12310	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
G8D25_RS12320	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
G8D25_RS12335	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
G8D25_RS12360	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
G8D25_RS12370	ENOG4105D6S	protein involved in catabolism of external DNA
G8D25_RS12375	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D25_RS12380	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
G8D25_RS12385	ENOG4107QMS	site-determining protein
G8D25_RS12390	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
G8D25_RS12395	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
G8D25_RS12405	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
G8D25_RS12425	ENOG4105DHQ	Histidine kinase
G8D25_RS12440	ENOG4105KZX	Pterin carbinolamine dehydratase
G8D25_RS12445	ENOG4105MIR	Phenylalanine 4-monooxygenase
G8D25_RS12450	ENOG4105EW9	transcriptional regulator AsnC family
G8D25_RS12460	ENOG4105F84	Ornithine cyclodeaminase
G8D25_RS12490	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
G8D25_RS12495	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
G8D25_RS12500	ENOG4105C0Z	ABC transporter
G8D25_RS12505	ENOG4108IV0	ABC, transporter
G8D25_RS12515	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D25_RS12550	ENOG4105HEI	LysR family (Transcriptional regulator
G8D25_RS12555	ENOG4105VRT	cytoplasmic protein
G8D25_RS12560	ENOG4105EXG	Transcriptional regulator
G8D25_RS12575	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G8D25_RS12580	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G8D25_RS12585	ENOG4107QJE	Chromosome Partitioning Protein
G8D25_RS12590	ENOG4105FA0	parb-like partition protein
G8D25_RS12600	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
G8D25_RS12605	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G8D25_RS12610	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G8D25_RS12615	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G8D25_RS12620	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G8D25_RS12625	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G8D25_RS12630	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G8D25_RS12635	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G8D25_RS12650	ENOG4105K4P	CoA-binding domain protein
G8D25_RS12670	ENOG4108K3A	Glutathione S-transferase
G8D25_RS12685	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS12705	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G8D25_RS12710	ENOG4105C25	Primosomal protein n'
G8D25_RS12715	ENOG4105C26	Dehydrogenase
G8D25_RS12720	ENOG4105CP9	extracellular ligand-binding receptor
G8D25_RS12730	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
G8D25_RS12735	ENOG4105EPD	Oligopeptide transporter, Opt family
G8D25_RS12745	ENOG4105E18	UPF0276 protein
G8D25_RS12775	ENOG4105EJQ	L-serine dehydratase
G8D25_RS12780	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G8D25_RS12785	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G8D25_RS12790	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G8D25_RS12805	ENOG4105C4R	Atp-dependent dna helicase
G8D25_RS12825	ENOG4105VJY	transcriptional regulator
G8D25_RS12830	ENOG4105NNS	Autoinducer synthesis protein
G8D25_RS12840	ENOG4105D4P	Coproporphyrinogen iii oxidase
G8D25_RS12855	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D25_RS12860	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G8D25_RS12865	ENOG41060W2	glyoxylate carboligase
G8D25_RS12870	ENOG4105EJC	lysr family transcriptional regulator
G8D25_RS12885	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
G8D25_RS12895	ENOG4105CK2	sodium dicarboxylate symporter
G8D25_RS12900	ENOG4105DHG	Allantoate amidinohydrolase
G8D25_RS12910	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G8D25_RS12935	ENOG4105C5X	domain protein
G8D25_RS12945	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G8D25_RS12950	ENOG41082RQ	UPF0102 protein
G8D25_RS12965	ENOG4107S7U	Sulfide dehydrogenase
G8D25_RS12970	ENOG4108594	Permease of the drug metabolite transporter
G8D25_RS12975	ENOG4105W2Z	cytochrome C, class I
G8D25_RS13000	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
G8D25_RS13005	ENOG4107QX9	Thiol disulfide interChange protein
G8D25_RS13010	ENOG4105CGH	5'-nucleotidase
G8D25_RS13055	ENOG4105VT3	DNA binding domain protein, excisionase family
G8D25_RS13220	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
G8D25_RS13335	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G8D25_RS13390	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
G8D25_RS13405	ENOG4107RDJ	Sulfotransferase
G8D25_RS13430	ENOG4105BZ8	glutamate synthase
G8D25_RS13460	ENOG4105KVH	Transcriptional regulator
G8D25_RS13475	ENOG4105CHM	Aminotransferase
G8D25_RS13485	ENOG4107791	aminotransferase class V
G8D25_RS13565	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
G8D25_RS13585	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
G8D25_RS13595	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS13600	ENOG4108NSC	Pfam:DUF88
G8D25_RS13625	ENOG4105C5I	Dehydrogenase
G8D25_RS13635	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G8D25_RS13640	ENOG4105C26	Dehydrogenase
G8D25_RS13645	ENOG4105CPD	ethanolamine ammonia-lyase
G8D25_RS13650	ENOG4107FQ9	ethanolamine ammonia-lyase
G8D25_RS13655	ENOG4105CJB	Exodeoxyribonuclease I
G8D25_RS13700	ENOG4105D7Q	type ii secretion system
G8D25_RS13710	ENOG4107QHF	type ii secretion system protein e
G8D25_RS13715	ENOG4105GVR	general secretion pathway protein D
G8D25_RS13740	ENOG4108WWZ	General secretion pathway protein J
G8D25_RS13750	ENOG4105VWV	general secretion pathway protein h
G8D25_RS13755	ENOG4108VAU	general secretion pathway protein G
G8D25_RS13775	ENOG4105F7P	transcriptional regulator AsnC family
G8D25_RS13800	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
G8D25_RS13805	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G8D25_RS13835	ENOG4108Z9W	Outer membrane porin
G8D25_RS13845	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
G8D25_RS13850	ENOG4105VMH	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria (By similarity)
G8D25_RS13915	ENOG4105KV4	Transcriptional regulator
G8D25_RS13935	ENOG4107RN6	Monooxygenase
G8D25_RS13940	ENOG4105BZU	Histidine kinase
G8D25_RS13945	ENOG41068CG	regulatoR
G8D25_RS13985	ENOG4105D94	Major Facilitator Superfamily
G8D25_RS13990	ENOG4105D8X	mechanosensitive ion channel
G8D25_RS14010	ENOG4107EXC	regulatoR
G8D25_RS14015	ENOG4105JJR	Histidine kinase
G8D25_RS14030	ENOG4105CSH	Transporter
G8D25_RS14035	ENOG4105CSH	Transporter
G8D25_RS14040	ENOG4107SZR	mannose-6-phosphate isomerase
G8D25_RS14045	ENOG4105DJ9	glucan biosynthesis protein
G8D25_RS14070	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G8D25_RS14095	ENOG4108IJ9	(ABC) transporter
G8D25_RS14105	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G8D25_RS14110	ENOG4105E98	transcriptional regulator DeoR family
G8D25_RS14155	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G8D25_RS14175	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G8D25_RS14180	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G8D25_RS14185	ENOG4108VZM	50s ribosomal protein L10
G8D25_RS14190	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G8D25_RS14195	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8D25_RS14200	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8D25_RS14205	ENOG4107FKF	Uncharacterized protein conserved in bacteria (DUF2138)
G8D25_RS14210	ENOG4108QJJ	Protein of unknown function (DUF1175)
G8D25_RS14215	ENOG4107S52	alpha-2-macroglobulin domain protein
G8D25_RS14220	ENOG41081SK	signal peptide protein
G8D25_RS14225	ENOG4105EDV	vault protein
G8D25_RS14230	ENOG4105EDV	vault protein
G8D25_RS14240	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G8D25_RS14245	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G8D25_RS14250	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G8D25_RS14265	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G8D25_RS14270	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G8D25_RS14280	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G8D25_RS14285	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G8D25_RS14290	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G8D25_RS14295	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G8D25_RS14300	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G8D25_RS14305	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G8D25_RS14315	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G8D25_RS14320	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G8D25_RS14325	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G8D25_RS14330	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G8D25_RS14335	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G8D25_RS14340	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G8D25_RS14345	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G8D25_RS14350	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G8D25_RS14355	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G8D25_RS14360	ENOG4105VPB	50S ribosomal protein L30
G8D25_RS14365	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G8D25_RS14370	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G8D25_RS14375	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G8D25_RS14380	ENOG41067V7	50S ribosomal protein L36
G8D25_RS14385	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G8D25_RS14390	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G8D25_RS14395	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G8D25_RS14400	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8D25_RS14405	ENOG4108ZT0	50S ribosomal protein l17
G8D25_RS14415	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
G8D25_RS14420	ENOG4105D52	delta-aminolevulinic acid dehydratase
G8D25_RS14425	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G8D25_RS14430	ENOG4106RE7	Cytochrome
G8D25_RS14440	ENOG4105CRE	cytochrome C
G8D25_RS14460	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
G8D25_RS14465	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
G8D25_RS14470	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G8D25_RS14480	ENOG4105XQ6	frataxin-like protein
G8D25_RS14515	ENOG4105E4G	Type IV pilus
G8D25_RS14520	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G8D25_RS14525	ENOG4105D49	3-dehydroquinate synthase
G8D25_RS14530	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G8D25_RS14560	ENOG4105DHJ	ABC, transporter
G8D25_RS14565	ENOG4105CY3	ABC transporter, permease
G8D25_RS14570	ENOG4107PE3	Mammalian cell entry related domain protein
G8D25_RS14575	ENOG410903C	(LipO)protein
G8D25_RS14590	ENOG4105DA5	(ABC) transporter
G8D25_RS14595	ENOG4105E3A	(ABC) transporter
G8D25_RS14605	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G8D25_RS14615	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G8D25_RS14620	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G8D25_RS14625	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G8D25_RS14630	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
G8D25_RS14635	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G8D25_RS14640	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G8D25_RS14645	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G8D25_RS14650	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G8D25_RS14655	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
G8D25_RS14665	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G8D25_RS14670	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G8D25_RS14675	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G8D25_RS14695	ENOG4105DHQ	Histidine kinase
G8D25_RS14710	ENOG4108Z9W	Outer membrane porin
G8D25_RS14715	ENOG4105C0H	protease
G8D25_RS14720	ENOG4107QNR	UPF0135 protein
G8D25_RS14725	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G8D25_RS14730	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G8D25_RS14735	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G8D25_RS14740	ENOG4105EIX	cytochrome c1
G8D25_RS14745	ENOG4107MKT	Stringent starvation protein a
G8D25_RS14750	ENOG4105KB2	stringent starvation protein b
G8D25_RS14760	ENOG4105W7K	Transcriptional regulator
G8D25_RS14765	ENOG4108YIQ	Alpha beta hydrolase
G8D25_RS14785	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G8D25_RS14790	ENOG4105E0K	tonB-dependent siderophore receptor
G8D25_RS14795	ENOG4108S3W	Anti-feci sigma factor, fecr
G8D25_RS14805	ENOG4105E2S	oxidase) subunit II
G8D25_RS14810	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G8D25_RS14815	ENOG4105CCU	oxidase (Subunit III)
G8D25_RS14820	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
G8D25_RS14825	ENOG4105C5H	ABC transporter
G8D25_RS14845	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
G8D25_RS14850	ENOG4105DJ9	glucan biosynthesis protein
G8D25_RS14860	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
G8D25_RS14870	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G8D25_RS14880	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G8D25_RS14885	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G8D25_RS14895	ENOG4105C3G	gtp-binding protein
G8D25_RS14930	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
G8D25_RS14935	ENOG4105C0H	protease
G8D25_RS14955	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G8D25_RS14965	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G8D25_RS14970	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G8D25_RS14980	ENOG4105DDQ	anthranilate synthase
G8D25_RS14990	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8D25_RS15000	ENOG4105NWN	ApaG protein
G8D25_RS15020	ENOG4108ZJI	phenylacetic acid degradation protein
G8D25_RS15025	ENOG4108UKI	Enoyl-CoA hydratase
G8D25_RS15030	ENOG4105E39	Enoyl-CoA hydratase
G8D25_RS15050	ENOG4105CH2	amidohydrolase
G8D25_RS15055	ENOG4105DEF	Extracellular solute-binding protein, family 5
G8D25_RS15060	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS15065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS15070	ENOG4105C3U	ABC transporter
G8D25_RS15075	ENOG4108JQ7	(ABC) transporter
G8D25_RS15080	ENOG4105CWC	Acetylornithine deacetylase
G8D25_RS15090	ENOG4105DM4	PTS System
G8D25_RS15095	ENOG4105DE4	1-phosphofructokinase
G8D25_RS15100	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G8D25_RS15105	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS15110	ENOG4108J2R	molybdopterin oxidoreductase
G8D25_RS15120	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS15125	ENOG4105CSH	Transporter
G8D25_RS15130	ENOG4108Z9W	Outer membrane porin
G8D25_RS15135	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
G8D25_RS15140	ENOG4108V6E	Cell division protein mraZ
G8D25_RS15145	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G8D25_RS15150	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G8D25_RS15155	ENOG4105CJN	penicillin-binding protein
G8D25_RS15160	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G8D25_RS15165	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G8D25_RS15170	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G8D25_RS15175	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G8D25_RS15185	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G8D25_RS15190	ENOG4105DFU	Cell wall formation (By similarity)
G8D25_RS15195	ENOG4105CPF	Cell wall formation (By similarity)
G8D25_RS15200	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G8D25_RS15205	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G8D25_RS15210	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G8D25_RS15220	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D25_RS15230	ENOG4105DR5	peptidase
G8D25_RS15235	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G8D25_RS15240	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G8D25_RS15250	ENOG4105M6F	mutator MutT protein
G8D25_RS15255	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G8D25_RS15260	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
G8D25_RS15265	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G8D25_RS15270	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
G8D25_RS15275	ENOG4105D7Q	type ii secretion system
G8D25_RS15285	ENOG4108JU6	CBS domain protein
G8D25_RS15295	ENOG4105EAH	synthase
G8D25_RS15300	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G8D25_RS15305	ENOG4105K46	50S ribosomal protein l27
G8D25_RS15310	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G8D25_RS15315	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G8D25_RS15325	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G8D25_RS15330	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G8D25_RS15335	ENOG4105E4C	Lytic transglycosylase catalytic
G8D25_RS15345	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
G8D25_RS15350	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G8D25_RS15355	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8D25_RS15360	ENOG4105CRE	cytochrome C
G8D25_RS15370	ENOG4107TUY	Histidine kinase
G8D25_RS15375	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS15385	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8D25_RS15390	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8D25_RS15405	ENOG4105FKN	transcriptional regulator, AsnC family
G8D25_RS15455	ENOG4107T4Z	adenosine kinase
G8D25_RS15460	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
G8D25_RS15470	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G8D25_RS15475	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G8D25_RS15480	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G8D25_RS15485	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G8D25_RS15490	ENOG4105K63	Thioredoxin
G8D25_RS15505	ENOG4105IPS	esterase
G8D25_RS15510	ENOG410807V	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
G8D25_RS15525	ENOG4105E2X	shikimate dehydrogenase
G8D25_RS15530	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G8D25_RS15540	ENOG4107QUT	magnesium and cobalt transport protein CorA
G8D25_RS15545	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
G8D25_RS15550	ENOG4105PGM	cation diffusion facilitator family transporter
G8D25_RS15555	ENOG4105CEV	competence damage-inducible protein
G8D25_RS15560	ENOG4108ZAI	phosphatidylglycerophosphatase a
G8D25_RS15565	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G8D25_RS15590	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G8D25_RS15605	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G8D25_RS15610	ENOG4105G2Y	Transcriptional regulator
G8D25_RS15615	ENOG41090R7	Ferric uptake
G8D25_RS15620	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G8D25_RS15625	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G8D25_RS15630	ENOG4105C8T	Leucyl-tRNA synthetase
G8D25_RS15640	ENOG4105DJF	DNA polymerase III, delta' subunit
G8D25_RS15645	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G8D25_RS15650	ENOG4108YXA	Membrane
G8D25_RS15655	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G8D25_RS15665	ENOG4105BZU	Histidine kinase
G8D25_RS15670	ENOG4105BZU	Histidine kinase
G8D25_RS15680	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G8D25_RS15685	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8D25_RS15690	ENOG4105W8H	transhydrogenase (subunit alpha
G8D25_RS15695	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G8D25_RS15700	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8D25_RS15715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8D25_RS15735	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G8D25_RS15740	ENOG4105CBC	glutamate synthase
G8D25_RS15745	ENOG4108U78	Glutathione S-transferase
G8D25_RS15750	ENOG4107QTF	adenylosuccinate lyase
G8D25_RS15755	ENOG4105DS1	cytochrome b561
G8D25_RS15765	ENOG4108YYC	ycei family
G8D25_RS15770	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8D25_RS15775	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8D25_RS15780	ENOG4105VIE	preprotein translocase, subunit YajC
G8D25_RS15785	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G8D25_RS15790	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G8D25_RS15795	ENOG4105CB5	ATP-dependent DNA helicase recG
G8D25_RS15850	ENOG4107RCH	Diaminopropionate ammonia-lyase
G8D25_RS15855	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
G8D25_RS15860	ENOG4108XM1	transcriptional regulator AsnC family
G8D25_RS15865	ENOG4105CH2	amidohydrolase
G8D25_RS15875	ENOG4105RPH	Inner membrane protein YddG
G8D25_RS15885	ENOG4105C5Q	Transcriptional regulator
G8D25_RS15900	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G8D25_RS15910	ENOG4105II7	pyrroline-5-carboxylate reductase
G8D25_RS15915	ENOG4105DFA	alanine racemase domain protein
G8D25_RS15920	ENOG4105CZX	twitching motility protein
G8D25_RS15925	ENOG4105CZX	twitching motility protein
G8D25_RS15980	ENOG41067MG	lrgb family
G8D25_RS15985	ENOG4105VAW	lrga family
G8D25_RS15990	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G8D25_RS15995	ENOG4105EU8	FAD linked oxidase domain protein
G8D25_RS16000	ENOG4105CQB	FAD linked oxidase domain protein
G8D25_RS16005	ENOG4105CQB	FAD linked oxidase domain protein
G8D25_RS16010	ENOG4108WBT	adenosyltransferase
G8D25_RS16015	ENOG4105D64	Mechanosensitive ion channel
G8D25_RS16030	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8D25_RS16040	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G8D25_RS16055	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G8D25_RS16065	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G8D25_RS16070	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G8D25_RS16080	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G8D25_RS16085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G8D25_RS16090	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G8D25_RS16095	ENOG4105CZE	histidine utilization repressor
G8D25_RS16100	ENOG4105CGP	Urocanate hydratase
G8D25_RS16105	ENOG4105C84	Histidine ammonia-lyase
G8D25_RS16110	ENOG41088SP	formiminoglutamate hydrolase
G8D25_RS16115	ENOG4105CI2	imidazolone-5-propionate hydrolase
G8D25_RS16120	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G8D25_RS16125	ENOG4105VEJ	Heat shock protein
G8D25_RS16135	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G8D25_RS16145	ENOG4105NXH	GreA GreB family elongation factor
G8D25_RS16150	ENOG4105CFG	Acts as a chaperone (By similarity)
G8D25_RS16155	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G8D25_RS16165	ENOG4108JJB	ABC transporter
G8D25_RS16170	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS16175	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G8D25_RS16185	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8D25_RS16200	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
G8D25_RS16205	ENOG4105C02	permease
G8D25_RS16210	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G8D25_RS16225	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G8D25_RS16235	ENOG4105CF1	Alkylated DNA repair protein
G8D25_RS16240	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G8D25_RS16250	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G8D25_RS16255	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G8D25_RS16260	ENOG4105DY2	Paraquat-inducible protein b
G8D25_RS16275	ENOG4105DQR	SNARE associated Golgi
G8D25_RS16285	ENOG4105CJR	Integral membrane protein (MviN
G8D25_RS16290	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
G8D25_RS16300	ENOG4105DBV	ornithine carbamoyltransferase
G8D25_RS16305	ENOG4105CDH	Citrulline--aspartate ligase
G8D25_RS16310	ENOG4105NBK	UPF0345 protein
G8D25_RS16320	ENOG4105D4A	Cell wall formation (By similarity)
G8D25_RS16325	ENOG4108VPT	UPF0234 protein
G8D25_RS16335	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G8D25_RS16340	ENOG4108Z66	YbaK ebsC protein
G8D25_RS16345	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D25_RS16350	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G8D25_RS16365	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G8D25_RS16370	ENOG4105K8N	protein family UPF0079, ATPase
G8D25_RS16375	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G8D25_RS16380	ENOG4105DHU	Bile acid
G8D25_RS16385	ENOG4108M0I	Transcriptional regulator
G8D25_RS16395	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G8D25_RS16400	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G8D25_RS16405	ENOG4105W49	UPF0434 protein
G8D25_RS16410	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G8D25_RS16415	ENOG4105M15	transport protein ExbD
G8D25_RS16425	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G8D25_RS16430	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8D25_RS16435	ENOG4105CHR	reductase
G8D25_RS16465	ENOG4105CSH	Transporter
G8D25_RS16475	ENOG4105CY2	Citrate transporter
G8D25_RS16490	ENOG4105E90	ABC transporter
G8D25_RS16495	ENOG4105CPI	Metal Dependent Phosphohydrolase
G8D25_RS16510	ENOG4105F87	Dehydratase
G8D25_RS16550	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
G8D25_RS16555	ENOG4105CGZ	zinc metallopeptidase
G8D25_RS16565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G8D25_RS16575	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G8D25_RS16580	ENOG4108SB3	DoxX Family
G8D25_RS16585	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8D25_RS16590	ENOG4105CR8	Transcriptional regulator
G8D25_RS16595	ENOG4105F04	LysR family Transcriptional regulator
G8D25_RS16600	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
G8D25_RS16635	ENOG4105DFP	Integrase
G8D25_RS16705	ENOG4105VEQ	Cold shock protein
G8D25_RS16710	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G8D25_RS16715	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D25_RS16720	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G8D25_RS16725	ENOG4105DEN	Luciferase family
G8D25_RS16730	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G8D25_RS16740	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G8D25_RS16745	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G8D25_RS16750	ENOG4105DTN	riboflavin biosynthesis protein ribF
G8D25_RS16755	ENOG4105BZU	Histidine kinase
G8D25_RS16760	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS16765	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G8D25_RS16780	ENOG4105EGS	Mechanosensitive ion channel
G8D25_RS16790	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G8D25_RS16795	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G8D25_RS16800	ENOG4108IYU	L-aspartate oxidase
G8D25_RS16805	ENOG4105W0E	50S ribosomal protein L33
G8D25_RS16810	ENOG4105KDC	50s ribosomal protein l28
G8D25_RS16815	ENOG4105W5Q	DNA repair protein (RadC
G8D25_RS16820	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G8D25_RS16825	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G8D25_RS16830	ENOG4105CP9	extracellular ligand-binding receptor
G8D25_RS16835	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D25_RS16840	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G8D25_RS16845	ENOG4105C0Z	ABC transporter
G8D25_RS16860	ENOG4105C8Y	Acetylornithine aminotransferase
G8D25_RS16895	ENOG4106RE7	Cytochrome
G8D25_RS16905	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D25_RS16915	ENOG4107R11	Transcriptional regulator
G8D25_RS16920	ENOG4107TSN	permease
G8D25_RS16925	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G8D25_RS16945	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
G8D25_RS16950	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G8D25_RS16975	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G8D25_RS16980	ENOG4105MYG	DNA polymerase iii, chi subunit
G8D25_RS16990	ENOG4105C01	Dihydroxy-acid dehydratase
G8D25_RS16995	ENOG4106NZI	LysR family Transcriptional regulator
G8D25_RS17000	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G8D25_RS17040	ENOG4105E0A	ABC, transporter
G8D25_RS17050	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G8D25_RS17055	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G8D25_RS17070	ENOG4105EFT	decarboxylase
G8D25_RS17075	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G8D25_RS17080	ENOG4108YZT	Adenosylcobinamide kinase
G8D25_RS17085	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G8D25_RS17095	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G8D25_RS17100	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G8D25_RS17115	ENOG4105MA0	exported protein
G8D25_RS17125	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G8D25_RS17165	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G8D25_RS17170	ENOG4105QAX	Iron-sulfur
G8D25_RS17190	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8D25_RS17195	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G8D25_RS17200	ENOG4105DHP	deoxycytidine triphosphate deaminase
G8D25_RS17205	ENOG4105CXN	decarboxylase
G8D25_RS17225	ENOG41060M0	Crispr-associated protein, cse4 family
G8D25_RS17230	ENOG4108VWQ	crispr-associated protein
G8D25_RS17240	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
G8D25_RS17245	ENOG4105PWE	CRISPR-associated protein cas2
G8D25_RS17250	ENOG4105CH7	arginosuccinase
G8D25_RS17260	ENOG4105I6B	RNA polymerase
G8D25_RS17280	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
G8D25_RS17285	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G8D25_RS17290	ENOG41076E6	Uroporphyrinogen-III Synthase
G8D25_RS17310	ENOG4105CSP	Major Facilitator Superfamily
G8D25_RS17325	ENOG4105F0N	pyrophosphate phospho-hydrolase
G8D25_RS17350	ENOG4108YZA	Nitrogen regulatory protein pii
G8D25_RS17355	ENOG4105EN6	Membrane
G8D25_RS17365	ENOG4105C3M	thioredoxin reductase
G8D25_RS17375	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
G8D25_RS17390	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G8D25_RS17410	ENOG4105WH1	Two component transcriptional regulator luxr family
G8D25_RS17420	ENOG4108VAU	general secretion pathway protein G
G8D25_RS17430	ENOG4107QHF	type ii secretion system protein e
G8D25_RS17465	ENOG4108VAU	general secretion pathway protein G
G8D25_RS17580	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
G8D25_RS17585	ENOG4105C37	(CBS) domain
G8D25_RS17625	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8D25_RS17630	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS17640	ENOG4105DRP	amino acid AbC transporter
G8D25_RS17645	ENOG4105EAD	ABC transporter
G8D25_RS17650	ENOG4107UBR	Extracellular solute-binding protein family 3
G8D25_RS17660	ENOG4107HP6	Transcriptional regulator
G8D25_RS17670	ENOG4107QNJ	CoA-transferase subunit B
G8D25_RS17675	ENOG4105CHU	acetyl-coa acetyltransferase
G8D25_RS17680	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
G8D25_RS17685	ENOG4105F2Z	3-oxoadipate enol-lactonase
G8D25_RS17690	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
G8D25_RS17705	ENOG4105C0Z	ABC transporter
G8D25_RS17710	ENOG4108IV0	ABC, transporter
G8D25_RS17715	ENOG4105CAD	extracellular ligand-binding receptor
G8D25_RS17730	ENOG4105GSQ	TM1410 hypothetical-related protein
G8D25_RS17740	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G8D25_RS17755	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G8D25_RS17760	ENOG4105C4R	Atp-dependent dna helicase
G8D25_RS17770	ENOG4105CUV	Homoserine Kinase
G8D25_RS17780	ENOG4108URH	decarboxylase
G8D25_RS17785	ENOG4105C2M	dna polymerase I
G8D25_RS17790	ENOG4105CEP	NADH dehydrogenase
G8D25_RS17795	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
G8D25_RS17805	ENOG4105KHC	sulfurtransferase
G8D25_RS17825	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G8D25_RS17830	ENOG4105CTB	Polyprenyl synthetase
G8D25_RS17835	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G8D25_RS17840	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
G8D25_RS17845	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G8D25_RS17850	ENOG4105CBX	hi0933 family
G8D25_RS17855	ENOG4105KTH	gatB Yqey
G8D25_RS17865	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D25_RS17890	ENOG4105C1J	atp-dependent rna helicase
G8D25_RS17895	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G8D25_RS17900	ENOG4105EQ1	Transcriptional regulator
G8D25_RS17920	ENOG4105C72	UPF0176 protein
G8D25_RS17940	ENOG4106WTF	Glycosyl transferase, family 2
G8D25_RS17950	ENOG4105BZ1	(ABC) transporter
G8D25_RS17970	ENOG4105C03	ribonuclease
G8D25_RS17975	ENOG4108Z03	MAF-like protein
G8D25_RS17980	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G8D25_RS17985	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
G8D25_RS17995	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G8D25_RS18000	ENOG4105C12	Phosphoribosylglycinamide synthetase
G8D25_RS18005	ENOG4105CDY	transcriptional regulatory protein
G8D25_RS18010	ENOG4105D7A	ATP-binding protein
G8D25_RS18015	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G8D25_RS18020	ENOG4106UX7	integral membrane protein
G8D25_RS18025	ENOG4105CHR	reductase
G8D25_RS18030	ENOG4108Z5K	methylglyoxal synthase
G8D25_RS18035	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
G8D25_RS18045	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
G8D25_RS18050	ENOG4105C6X	Major Facilitator
G8D25_RS18095	ENOG4105UIB	(ABC) transporter
G8D25_RS18100	ENOG4105C2J	ABC transporter
G8D25_RS18105	ENOG4105C2C	drug resistance transporter, Bcr CflA
G8D25_RS18110	ENOG4105P4J	Allophanate hydrolase, subunit 1
G8D25_RS18115	ENOG4107R7A	Allophanate hydrolase subunit 2
G8D25_RS18120	ENOG4105E7W	lamb ycsf family protein
G8D25_RS18135	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G8D25_RS18140	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
G8D25_RS18180	ENOG4105DFP	Integrase
G8D25_RS18245	ENOG4105CSA	Coproporphyrinogen iii oxidase
G8D25_RS18250	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G8D25_RS18255	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G8D25_RS18270	ENOG4105DSJ	YicC domain protein
G8D25_RS18275	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G8D25_RS18280	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G8D25_RS18295	ENOG4108RRZ	Transcription elongation factor GreB
G8D25_RS18315	ENOG4109066	lysm domain bon superfamily protein
G8D25_RS18330	ENOG4105CD8	aminopeptidase N
G8D25_RS18350	ENOG4108Z9W	Outer membrane porin
G8D25_RS18365	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G8D25_RS18370	ENOG4105C2W	permease
G8D25_RS18380	ENOG4105VT2	5-hydroxyisourate hydrolase
G8D25_RS18395	ENOG4107RSM	transcriptional regulator
G8D25_RS18400	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
G8D25_RS18425	ENOG4105DQ4	alcohol dehydrogenase
G8D25_RS18440	ENOG4105CBN	LysR family transcriptional regulator
G8D25_RS18455	ENOG4107QUY	Guanine deaminase
G8D25_RS18470	ENOG4105C7W	Xanthine dehydrogenase
G8D25_RS18495	ENOG4105CV6	ABC transporter, permease
G8D25_RS18515	ENOG4108URH	decarboxylase
G8D25_RS18520	ENOG4107Z3H	Transcriptional regulator, TetR family
G8D25_RS18525	ENOG41080IJ	Diacylglycerol kinase
G8D25_RS18530	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G8D25_RS18565	ENOG4105C7K	acetolactate synthase
G8D25_RS18570	ENOG4108ZP8	Acetolactate synthase small subunit
G8D25_RS18575	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G8D25_RS18580	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
G8D25_RS18585	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G8D25_RS18590	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G8D25_RS18605	ENOG4105ES9	amino acid
G8D25_RS18610	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G8D25_RS18615	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G8D25_RS18620	ENOG4106TCE	
G8D25_RS18625	ENOG4105CPQ	Dehydrogenase
G8D25_RS18630	ENOG4105CP7	Triose-phosphate isomerase
G8D25_RS18635	ENOG4107EJC	Preprotein translocase subunit SecG
G8D25_RS18650	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D25_RS18655	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G8D25_RS18660	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D25_RS18670	ENOG4107QIZ	NADH dehydrogenase
G8D25_RS18675	ENOG4108IEH	NADH dehydrogenase subunit g
G8D25_RS18680	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G8D25_RS18685	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D25_RS18690	ENOG4105DF2	NADH dehydrogenase subunit j
G8D25_RS18695	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D25_RS18705	ENOG4105C8S	subunit m
G8D25_RS18710	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D25_RS18730	ENOG4105CC9	acyl-Coa dehydrogenase
G8D25_RS18735	ENOG4105C1G	acyl-Coa dehydrogenase
G8D25_RS18740	ENOG4105DXM	phenylacetic acid degradation protein
G8D25_RS18755	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D25_RS18765	ENOG4105C0Z	ABC transporter
G8D25_RS18770	ENOG4108IV0	ABC, transporter
G8D25_RS18775	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G8D25_RS18780	ENOG4108YZ9	Urea amidohydrolase subunit gamma
G8D25_RS18790	ENOG4105KI2	Urea amidohydrolase subunit beta
G8D25_RS18800	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
G8D25_RS18805	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G8D25_RS18810	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
G8D25_RS18835	ENOG4105CYM	Glutathione S-transferase
G8D25_RS18875	ENOG4108UKI	Enoyl-CoA hydratase
G8D25_RS18880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D25_RS18885	ENOG4105IU3	Glutathione S-transferase
G8D25_RS18890	ENOG4105CHM	Aminotransferase
G8D25_RS18900	ENOG4105D1Q	UPF0246 protein
G8D25_RS18915	ENOG4105DEF	Extracellular solute-binding protein, family 5
G8D25_RS18930	ENOG4107QM5	aconitate hydratase
G8D25_RS18935	ENOG4105DXD	2-methylcitrate dehydratase
G8D25_RS18950	ENOG4105CR4	methylisocitrate lyase
G8D25_RS18955	ENOG4105CR4	methylisocitrate lyase
G8D25_RS18960	ENOG4105CR4	methylisocitrate lyase
G8D25_RS18970	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G8D25_RS18975	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8D25_RS18985	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
G8D25_RS18990	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G8D25_RS18995	ENOG4105E33	succinate dehydrogenase
G8D25_RS19000	ENOG41060IS	Flavinator of succinate dehydrogenase
G8D25_RS19005	ENOG4105BZN	citrate synthase
G8D25_RS19010	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G8D25_RS19015	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G8D25_RS19020	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D25_RS19040	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G8D25_RS19045	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G8D25_RS19050	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G8D25_RS19060	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G8D25_RS19065	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G8D25_RS19070	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G8D25_RS19085	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G8D25_RS19090	ENOG4105HAC	ABC-2 type transporter
G8D25_RS19125	ENOG4108ZJF	Glcg protein
G8D25_RS19135	ENOG4105SG9	biopolymer transport protein, ExbD
G8D25_RS19170	ENOG4105CK2	sodium dicarboxylate symporter
G8D25_RS19175	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G8D25_RS19185	ENOG4108TEB	UPF0114 protein
G8D25_RS19190	ENOG4108PCN	EamA-like transporter family
G8D25_RS19195	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8D25_RS19200	ENOG4107QN1	sodium solute
G8D25_RS19220	ENOG4105VJY	transcriptional regulator
G8D25_RS19230	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS19270	ENOG4105DEF	Extracellular solute-binding protein, family 5
G8D25_RS19280	ENOG4105C3U	ABC transporter
G8D25_RS19285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS19290	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS19340	ENOG4107RZZ	dna polymerase iii epsilon subunit
G8D25_RS19375	ENOG4105CMM	transposase
G8D25_RS19555	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
G8D25_RS19560	ENOG4105CSM	endonuclease III
G8D25_RS19565	ENOG4108R3D	Electron transport complex
G8D25_RS19570	ENOG4108W9H	Tetr family transcriptional regulator
G8D25_RS19585	ENOG4105CGF	Aromatic amino acid aminotransferase
G8D25_RS19590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G8D25_RS19600	ENOG4108RVA	ribokinase
G8D25_RS19605	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS19610	ENOG4105CNN	ABC, transporter
G8D25_RS19615	ENOG4105C2J	ABC transporter
G8D25_RS19620	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
G8D25_RS19630	ENOG4105C3J	Cysteine desulfurase
G8D25_RS19635	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G8D25_RS19640	ENOG4108Z4V	iron-sulfur cluster assembly
G8D25_RS19650	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
G8D25_RS19655	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
G8D25_RS19660	ENOG4108ZIT	Ferredoxin, 2FE-2S
G8D25_RS19665	ENOG4105WVQ	Fe-S assembly protein IscX
G8D25_RS19680	ENOG410904N	short-chain dehydrogenase reductase
G8D25_RS19690	ENOG4107RH7	Nicotinate phosphoribosyltransferase
G8D25_RS19695	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
G8D25_RS19705	ENOG4105C5I	Dehydrogenase
G8D25_RS19720	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G8D25_RS19725	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G8D25_RS19730	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G8D25_RS19735	ENOG4105C03	ribonuclease
G8D25_RS19740	ENOG4105EI2	Pseudouridine synthase
G8D25_RS19745	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8D25_RS19760	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G8D25_RS19765	ENOG4108UHJ	MAF-like protein
G8D25_RS19770	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G8D25_RS19775	ENOG4105VGS	50s ribosomal protein l32
G8D25_RS19780	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
G8D25_RS19785	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G8D25_RS19790	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G8D25_RS19795	ENOG4105CHR	reductase
G8D25_RS19800	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G8D25_RS19805	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G8D25_RS19815	ENOG4105EMN	RNA polymerase sigma factor
G8D25_RS19830	ENOG4105C0H	protease
G8D25_RS19840	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G8D25_RS19845	ENOG4105C3F	Signal peptidase i
G8D25_RS19855	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G8D25_RS19860	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G8D25_RS19865	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G8D25_RS19870	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G8D25_RS19875	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G8D25_RS19885	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G8D25_RS19895	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G8D25_RS19925	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D25_RS19935	ENOG4105BZU	Histidine kinase
G8D25_RS19940	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8D25_RS19950	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
G8D25_RS19960	ENOG4105DPW	Major facilitator superfamily MFS_1
G8D25_RS19970	ENOG4108Z9W	Outer membrane porin
G8D25_RS19980	ENOG4108Z9W	Outer membrane porin
G8D25_RS20025	ENOG4105D2S	major facilitator superfamily
G8D25_RS20030	ENOG4108M0I	Transcriptional regulator
G8D25_RS20050	ENOG4106A3M	Cytochrome p-450
G8D25_RS20075	ENOG4105DUM	transcriptional regulator, lysR family
G8D25_RS20080	ENOG4105HMI	Membrane
G8D25_RS20105	ENOG4108Z4U	Ferredoxin
G8D25_RS20110	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G8D25_RS20125	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G8D25_RS20130	ENOG4105EYA	deoxyribonuclease
G8D25_RS20135	ENOG4108EC8	DNA internalization-related competence protein ComEC
G8D25_RS20160	ENOG4108MUZ	hydrolase
G8D25_RS20165	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G8D25_RS20170	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G8D25_RS20180	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G8D25_RS20185	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G8D25_RS20195	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G8D25_RS20200	ENOG4108Z0R	Transferase
G8D25_RS20205	ENOG4105ED9	Protein of unknown function (DUF455)
G8D25_RS20210	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G8D25_RS20215	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
G8D25_RS20230	ENOG4105CAY	ferredoxin--nadp reductase
G8D25_RS20235	ENOG4105DB7	PHP domain protein
G8D25_RS20240	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G8D25_RS20245	ENOG4108Z4T	Peptidase M50
G8D25_RS20250	ENOG4105C31	Tryptophanyl-tRNA synthetase
G8D25_RS20255	ENOG4108YRB	methyltransferase
G8D25_RS20260	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G8D25_RS20265	ENOG4105GJM	(LipO)protein
G8D25_RS20270	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G8D25_RS20280	ENOG4105EZE	Cupin 4 family protein
G8D25_RS20285	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G8D25_RS20295	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G8D25_RS20300	ENOG4105HEI	LysR family (Transcriptional regulator
G8D25_RS20310	ENOG4105CV8	reductase
G8D25_RS20325	ENOG4108RPX	mosc domain containing protein
G8D25_RS20340	ENOG4105ECY	inositol monophosphatase
G8D25_RS20350	ENOG4105D7W	serine acetyltransferase
G8D25_RS20355	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
G8D25_RS20385	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G8D25_RS20390	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G8D25_RS20395	ENOG4105CFH	Aspartokinase
G8D25_RS20405	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G8D25_RS20410	ENOG4105E43	Extracellular solute-binding protein, family 5
G8D25_RS20420	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
G8D25_RS20425	ENOG4108JQ5	ABC transporter
G8D25_RS20430	ENOG4105K4H	Nlp p60 protein
G8D25_RS20435	ENOG4105D78	K07001 NTE family protein
G8D25_RS20440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G8D25_RS20475	ENOG4107QI1	Mate efflux family protein
G8D25_RS20485	ENOG4105NRA	50s ribosomal protein l31 type b
G8D25_RS20510	ENOG4105K63	Thioredoxin
G8D25_RS20535	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G8D25_RS20540	ENOG41061CK	Antibiotic biosynthesis monooxygenase
G8D25_RS20580	ENOG4108WUH	Transcriptional regulator, TetR family
G8D25_RS20595	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G8D25_RS20605	ENOG4108K5P	(LipO)protein
G8D25_RS20625	ENOG4108MN8	Membrane
G8D25_RS20630	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G8D25_RS20635	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G8D25_RS20650	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G8D25_RS20670	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G8D25_RS20675	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G8D25_RS20680	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G8D25_RS20685	ENOG4107QJR	hflk protein
G8D25_RS20690	ENOG4105EPW	hflc protein
G8D25_RS20700	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
G8D25_RS20705	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G8D25_RS20710	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
G8D25_RS20720	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G8D25_RS20725	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G8D25_RS20730	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G8D25_RS20735	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G8D25_RS20745	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
G8D25_RS20755	ENOG4108NVR	Methyl-accepting chemotaxis
G8D25_RS20760	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
G8D25_RS20765	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
G8D25_RS20770	ENOG4105NYY	transcriptional regulator, RpiR
G8D25_RS20820	ENOG4105C2J	ABC transporter
G8D25_RS20825	ENOG4108HWV	)-transporter
G8D25_RS20835	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
G8D25_RS20845	ENOG4105DH8	myo-inositol catabolism
G8D25_RS20850	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
G8D25_RS20890	ENOG4105CEV	competence damage-inducible protein
G8D25_RS20915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D25_RS20925	ENOG4105C59	p-type ATPase
G8D25_RS20930	ENOG4105BZ7	extracellular solute-binding protein family 1
G8D25_RS20940	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS20945	ENOG4108IJ9	(ABC) transporter
G8D25_RS20950	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
G8D25_RS20960	ENOG4105C7S	Dehydrogenase
G8D25_RS20965	ENOG4107QN2	dihydrolipoyl dehydrogenase
G8D25_RS20970	ENOG4105D6Z	AFG1 family ATPase
G8D25_RS20980	ENOG4105C59	p-type ATPase
G8D25_RS20990	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G8D25_RS21025	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G8D25_RS21035	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G8D25_RS21040	ENOG4105FE9	pseudouridine synthase
G8D25_RS21045	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G8D25_RS21050	ENOG4105CHV	Transcription elongation factor NusA
G8D25_RS21055	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G8D25_RS21060	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G8D25_RS21090	ENOG4105E39	Enoyl-CoA hydratase
G8D25_RS21095	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8D25_RS21110	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G8D25_RS21125	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G8D25_RS21130	ENOG4105DP0	ferredoxin-NADP reductase
G8D25_RS21140	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G8D25_RS21150	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G8D25_RS21155	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G8D25_RS21160	ENOG4105CDU	Replicative dna helicase
G8D25_RS21170	ENOG4107QXV	Phosphate transporter
G8D25_RS21185	ENOG4108IAB	Phoh family
G8D25_RS21190	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8D25_RS21195	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G8D25_RS21200	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G8D25_RS21215	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G8D25_RS21220	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
G8D25_RS21225	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G8D25_RS21235	ENOG4105CHM	Aminotransferase
G8D25_RS21240	ENOG4105D6E	homoserine dehydrogenase
G8D25_RS21250	ENOG4108RG0	uracil-dna glycosylase
G8D25_RS21255	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G8D25_RS21260	ENOG4105M00	molybdopterin converting factor, subunit 1
G8D25_RS21265	ENOG4108ZAF	Molybdopterin
G8D25_RS21270	ENOG4107Z6W	Protein CrcB homolog
G8D25_RS21275	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
G8D25_RS21280	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D25_RS21285	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8D25_RS21295	ENOG4105GVF	(ABC) transporter
G8D25_RS21300	ENOG4105GVF	(ABC) transporter
G8D25_RS21305	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
G8D25_RS21310	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS21315	ENOG4105E2Y	ABC, transporter
G8D25_RS21335	ENOG4108I5D	sulfate abc transporter
G8D25_RS21340	ENOG4105ECW	sulfate abc transporter
G8D25_RS21345	ENOG4108IJ6	ABC transporter
G8D25_RS21350	ENOG4107R11	Transcriptional regulator
G8D25_RS21365	ENOG4108HRK	Histidine kinase
G8D25_RS21370	ENOG4108VAC	response regulator
G8D25_RS21380	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
G8D25_RS21410	ENOG4105EJC	lysr family transcriptional regulator
G8D25_RS21425	ENOG4107QP3	malate synthase g
G8D25_RS21440	ENOG41072GX	Peptidase M22 Glycoprotease
G8D25_RS21445	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G8D25_RS21450	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G8D25_RS21455	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
G8D25_RS21460	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G8D25_RS21465	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G8D25_RS21470	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G8D25_RS21475	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
G8D25_RS21480	ENOG4105C5H	ABC transporter
G8D25_RS21490	ENOG4105D44	asparaginase
G8D25_RS21495	ENOG4108JQ6	ABC transporter
G8D25_RS21500	ENOG4105DEF	Extracellular solute-binding protein, family 5
G8D25_RS21510	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS21550	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G8D25_RS21560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G8D25_RS21565	ENOG4105KUZ	arsenate reductase
G8D25_RS21575	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
G8D25_RS21590	ENOG4105CPT	Alpha beta hydrolase
G8D25_RS21605	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G8D25_RS21610	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G8D25_RS21620	ENOG4105FE9	pseudouridine synthase
G8D25_RS21625	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G8D25_RS21630	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G8D25_RS21635	ENOG4105CE9	30S ribosomal protein S2
G8D25_RS21640	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G8D25_RS21645	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G8D25_RS21650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G8D25_RS21660	ENOG4105KNE	Phosphatidate cytidylyltransferase
G8D25_RS21665	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G8D25_RS21670	ENOG4105DZP	Membrane-associated zinc metalloprotease
G8D25_RS21675	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8D25_RS21680	ENOG4105X4K	outer membrane chaperone skp
G8D25_RS21685	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D25_RS21690	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G8D25_RS21695	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D25_RS21700	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D25_RS21705	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G8D25_RS21730	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G8D25_RS21735	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
G8D25_RS21745	ENOG4107QX8	SPFH domain, Band 7 family protein
G8D25_RS21750	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G8D25_RS21755	ENOG4108Z1B	Cyclase dehydrase
G8D25_RS21770	ENOG4105DXC	membrane
G8D25_RS21775	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G8D25_RS21785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8D25_RS21815	ENOG4105DDW	LysR family Transcriptional regulator
G8D25_RS21820	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
G8D25_RS21825	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
G8D25_RS21845	ENOG4105EJC	lysr family transcriptional regulator
G8D25_RS21855	ENOG4105CAF	HipA N-terminal domain protein
G8D25_RS21865	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G8D25_RS21870	ENOG4107XVI	synthase
G8D25_RS21875	ENOG4108Z6B	deaminase
G8D25_RS21880	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
G8D25_RS21885	ENOG4105C5H	ABC transporter
G8D25_RS21905	ENOG4105BZP	glycoside hydrolase 15-related
G8D25_RS21915	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D25_RS21930	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
G8D25_RS21970	ENOG4108RH0	Crea protein
G8D25_RS21975	ENOG4105CR8	Transcriptional regulator
G8D25_RS22005	ENOG4108TVJ	Nitroreductase
G8D25_RS22020	ENOG4108KB2	LysR family Transcriptional regulator
G8D25_RS22025	ENOG4105DTQ	mandelate racemase muconate lactonizing
G8D25_RS22040	ENOG4105FUY	alpha subunit
G8D25_RS22045	ENOG4108UKV	benzoate 1,2-dioxygenase
G8D25_RS22050	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
G8D25_RS22055	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
G8D25_RS22080	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G8D25_RS22085	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G8D25_RS22100	ENOG4105NX3	Membrane
G8D25_RS22120	ENOG4108MEJ	flavin reductase domain protein
G8D25_RS22175	ENOG4107QSN	dihydrolipoamide acetyltransferase
G8D25_RS22200	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G8D25_RS22205	ENOG4108IJ6	ABC transporter
G8D25_RS22210	ENOG4105ECW	sulfate abc transporter
G8D25_RS22220	ENOG4107QKW	extracellular solute-binding protein family 1
G8D25_RS22225	ENOG4105ETE	Transcriptional regulator (LacI family
G8D25_RS22245	ENOG4105F8V	Hydrolase, tatD family
G8D25_RS22255	ENOG4107QRG	dna polymerase iii
G8D25_RS22260	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G8D25_RS22265	ENOG4105HHA	aminodeoxychorismate lyase
G8D25_RS22270	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G8D25_RS22310	ENOG4105D74	hydrolase
G8D25_RS22330	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
G8D25_RS22345	ENOG4105CHR	reductase
G8D25_RS22350	ENOG4105CSU	acyl-Coa dehydrogenase
G8D25_RS22360	ENOG4108RWI	nicotinamidase
G8D25_RS22370	ENOG4108IQI	permease
G8D25_RS22375	ENOG4108IQI	permease
G8D25_RS22385	ENOG4108IV0	ABC, transporter
G8D25_RS22390	ENOG4105C0Z	ABC transporter
G8D25_RS22400	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D25_RS22410	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D25_RS22415	ENOG4105CNG	UPF0061 protein
G8D25_RS22420	ENOG4105E0X	reductase
G8D25_RS22425	ENOG4107835	probably involved in intracellular septation (By similarity)
G8D25_RS22435	ENOG4107TF3	peptidylprolyl cis-trans isomerase
G8D25_RS22450	ENOG4105D5T	phosphonate abc transporter
G8D25_RS22455	ENOG4108Z9W	Outer membrane porin
G8D25_RS22465	ENOG4105DHQ	Histidine kinase
G8D25_RS22470	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G8D25_RS22480	ENOG4105F38	ABC transporter, permease
G8D25_RS22485	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
G8D25_RS22490	ENOG4105CHR	reductase
G8D25_RS22495	ENOG4105CBN	LysR family transcriptional regulator
G8D25_RS22500	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G8D25_RS22520	ENOG4108ETH	Formylglycinamide ribotide synthetase
G8D25_RS22530	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G8D25_RS22535	ENOG4107QP8	phosphohexose isomerase
G8D25_RS22540	ENOG4108I0Y	(ABC) transporter
G8D25_RS22545	ENOG4108UJV	acyl-CoA thioesterase i
G8D25_RS22550	ENOG4105C3F	Signal peptidase i
G8D25_RS22555	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G8D25_RS22575	ENOG4105K70	DNA-binding protein
G8D25_RS22580	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G8D25_RS22585	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G8D25_RS22590	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G8D25_RS22595	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G8D25_RS22600	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G8D25_RS22660	ENOG4105E0F	Histidine kinase
G8D25_RS22665	ENOG4105D3R	alkyl hydroperoxide reductase
G8D25_RS22670	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
G8D25_RS22675	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G8D25_RS22680	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
G8D25_RS22685	ENOG4108JA2	transcriptioN-repair coupling factor
G8D25_RS22690	ENOG4105CWC	Acetylornithine deacetylase
G8D25_RS22695	ENOG4105EAC	phosphoserine phosphatase
G8D25_RS22715	ENOG4105CHU	acetyl-coa acetyltransferase
G8D25_RS22720	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G8D25_RS22725	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
G8D25_RS22735	ENOG4105CHR	reductase
G8D25_RS22740	ENOG4105CHU	acetyl-coa acetyltransferase
G8D25_RS22745	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G8D25_RS22755	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G8D25_RS22760	ENOG4105C34	Pseudouridine synthase
G8D25_RS22770	ENOG4105DVT	helicase
G8D25_RS22785	ENOG4105BZM	domain protein
G8D25_RS22810	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G8D25_RS22825	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G8D25_RS22830	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G8D25_RS22850	ENOG4107QR9	Iron-sulfur cluster binding protein
G8D25_RS22860	ENOG41069M3	Transcriptional regulator
G8D25_RS22865	ENOG41061WM	D-Alanyl-D-Alanine
G8D25_RS22885	ENOG4105DGU	Histone deacetylase
G8D25_RS22890	ENOG4108WFY	phasin family
G8D25_RS22900	ENOG4107QN2	dihydrolipoyl dehydrogenase
G8D25_RS22910	ENOG4107QSN	dihydrolipoamide acetyltransferase
G8D25_RS22915	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G8D25_RS22920	ENOG4105BZU	Histidine kinase
G8D25_RS22925	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G8D25_RS22930	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G8D25_RS22935	ENOG4105DGW	oligopeptidase A
G8D25_RS22940	ENOG4105DZC	cytosine deaminase
G8D25_RS22945	ENOG4105CGK	Exodeoxyribonuclease III
G8D25_RS22950	ENOG4108V8F	Transcriptional regulator, MarR family
G8D25_RS22970	ENOG4105CUB	amino acid
G8D25_RS22975	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G8D25_RS22990	ENOG4105X1V	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
G8D25_RS22995	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
G8D25_RS23010	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8D25_RS23015	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G8D25_RS23020	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G8D25_RS23025	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G8D25_RS23030	ENOG4105VJV	50s ribosomal protein L35
G8D25_RS23035	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G8D25_RS23040	ENOG4105C22	threonyL-tRNA synthetase
G8D25_RS23050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8D25_RS23055	ENOG4105M4H	endoribonuclease L-psp
G8D25_RS23065	ENOG4105DTD	Dehydrogenase
G8D25_RS23080	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G8D25_RS23085	ENOG4105CHR	reductase
G8D25_RS23090	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G8D25_RS23095	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G8D25_RS23100	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8D25_RS23105	ENOG4107S74	Lysophospholipid transporter LplT
G8D25_RS23120	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G8D25_RS23130	ENOG4107S2Z	UPF0761 membrane protein
G8D25_RS23135	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G8D25_RS23145	ENOG4105CQB	FAD linked oxidase domain protein
G8D25_RS23190	ENOG4105PF9	Transcriptional regulator
G8D25_RS23195	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D25_RS23210	ENOG4107RN3	metallophosphoesterase
G8D25_RS23245	ENOG4105DY2	Paraquat-inducible protein b
G8D25_RS23285	ENOG4107YZX	Universal stress protein
G8D25_RS23290	ENOG41080XQ	Signal transduction protein with cbs domains
G8D25_RS23300	ENOG4107YZX	Universal stress protein
G8D25_RS23305	ENOG4105BZU	Histidine kinase
G8D25_RS23315	ENOG41080HT	Transcriptional regulator, arsr family
G8D25_RS23325	ENOG4108VCT	Sulfite exporter TauE/SafE
G8D25_RS23360	ENOG4105C9X	ppx gppa phosphatase
G8D25_RS23365	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G8D25_RS23370	ENOG4105BZU	Histidine kinase
G8D25_RS23375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D25_RS23385	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G8D25_RS23390	ENOG4105E2Z	phosphate ABC transporter (Permease
G8D25_RS23395	ENOG4105C8U	phosphate abc transporter
G8D25_RS23400	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G8D25_RS23405	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G8D25_RS23410	ENOG4105EEI	dihydropteroate synthase
G8D25_RS23415	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G8D25_RS23420	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G8D25_RS23425	ENOG4105HBR	Rna-binding protein
G8D25_RS23435	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G8D25_RS23445	ENOG4108NIW	Leucine export protein LeuE
G8D25_RS23450	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G8D25_RS23455	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8D25_RS23460	ENOG4105E9H	Lytic Murein transglycosylase
G8D25_RS23465	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G8D25_RS23470	ENOG4105D1A	Methyltransferase
G8D25_RS23475	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G8D25_RS23510	ENOG4107YZX	Universal stress protein
G8D25_RS23570	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D25_RS23655	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8D25_RS23660	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G8D25_RS23665	ENOG4105T38	integral membrane protein
G8D25_RS23675	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8D25_RS23680	ENOG4108TGY	Glutathione S-transferase
G8D25_RS23700	ENOG4105DAA	L-lactate
G8D25_RS23715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D25_RS23720	ENOG4106JQ5	Transglycosylase SLT domain
G8D25_RS23725	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D25_RS23730	ENOG4105C5H	ABC transporter
G8D25_RS23740	ENOG4107RP9	extracellular solute-binding protein, family 3
G8D25_RS23755	ENOG4105CMQ	Chloride channel
G8D25_RS23770	ENOG4105C1J	atp-dependent rna helicase
G8D25_RS23775	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
G8D25_RS23785	ENOG4108ZCF	integral membrane protein
G8D25_RS23795	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G8D25_RS23805	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G8D25_RS23810	ENOG4105N42	UPF0307 protein
G8D25_RS23815	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G8D25_RS23820	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G8D25_RS23825	ENOG4105D0M	Protease HtpX homolog
G8D25_RS23830	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G8D25_RS23840	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G8D25_RS23850	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G8D25_RS23855	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G8D25_RS23860	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G8D25_RS23865	ENOG4105K5M	30s ribosomal protein S16
G8D25_RS23870	ENOG4105DKB	L-sorbosone dehydrogenase
G8D25_RS23895	ENOG4105EW9	transcriptional regulator AsnC family
G8D25_RS23900	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8D25_RS23905	ENOG4105CSU	acyl-Coa dehydrogenase
G8D25_RS23910	ENOG4105C10	Electron transfer flavoprotein
G8D25_RS23915	ENOG4105BZJ	Electron transfer flavoprotein
G8D25_RS23920	ENOG4105D01	(LipO)protein
G8D25_RS23925	ENOG4108UMI	ABC transporter, permease
G8D25_RS23930	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8D25_RS23940	ENOG4105CVE	Lytic murein transglycosylase
G8D25_RS23945	ENOG4105C6T	cysteine synthase
G8D25_RS23955	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
G8D25_RS23960	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G8D25_RS23965	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G8D25_RS23970	ENOG4105CFV	Tetratricopeptide repeat protein
G8D25_RS23980	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8D25_RS23985	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G8D25_RS23990	ENOG4105CAT	Cytidine monophosphate kinase
G8D25_RS23995	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G8D25_RS24005	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G8D25_RS24015	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G8D25_RS24025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D25_RS24030	ENOG4105UYK	outer membrane protein a
G8D25_RS24040	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G8D25_RS24045	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8D25_RS24120	ENOG4108PZW	LysR family Transcriptional regulator
G8D25_RS24125	ENOG4105CSH	Transporter