locus-tag	class	description
HI801_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HI801_RS00010	COG0592	DNA-directed DNA polymerase activity
HI801_RS00065	COG3781	membrane
HI801_RS00095	COG1126	abc transporter atp-binding protein
HI801_RS00100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS00115	COG0745	RESPONSE REGULATOR receiver
HI801_RS00120	COG0642	Histidine kinase
HI801_RS00135	COG2814	Major facilitator Superfamily
HI801_RS00150	COG1959	2 iron, 2 sulfur cluster binding
HI801_RS00175	COG0745	RESPONSE REGULATOR receiver
HI801_RS00180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI801_RS00200	COG4251	negative regulation of phosphorylation
HI801_RS00200	COG3706	GGDEF domain
HI801_RS00200	COG2203	Gaf domain
HI801_RS00200	COG5001	Diguanylate cyclase
HI801_RS00210	COG2205	protein histidine kinase activity
HI801_RS00215	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HI801_RS00220	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HI801_RS00225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HI801_RS00260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HI801_RS00270	COG1116	anion transmembrane transporter activity
HI801_RS00280	COG1254	Belongs to the acylphosphatase family
HI801_RS00290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HI801_RS00295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI801_RS00300	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HI801_RS00305	COG2894	cell division
HI801_RS00310	COG0850	regulation of cytokinetic process
HI801_RS00315	COG0737	Belongs to the 5'-nucleotidase family
HI801_RS00325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI801_RS00350	COG2154	pterin-4-alpha-carbinolamine dehydratase
HI801_RS00355	COG3186	Phenylalanine-4-hydroxylase
HI801_RS00370	COG2423	ornithine cyclodeaminase activity
HI801_RS00375	COG3047	cAMP biosynthetic process
HI801_RS00385	COG2217	Heavy metal translocating P-type atpase
HI801_RS00390	COG0789	Transcriptional regulator
HI801_RS00395	COG2267	carboxylic ester hydrolase activity
HI801_RS00460	COG3530	Putative quorum-sensing-regulated virulence factor
HI801_RS00465	COG0583	DNA-binding transcription factor activity
HI801_RS00485	COG0445	tRNA wobble uridine modification
HI801_RS00490	COG0357	Ribosomal RNA small subunit methyltransferase G
HI801_RS00495	COG1192	Involved in chromosome partitioning
HI801_RS00500	COG1475	DNA binding
HI801_RS00510	COG0356	it plays a direct role in the translocation of protons across the membrane
HI801_RS00520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HI801_RS00525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HI801_RS00530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HI801_RS00535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HI801_RS00540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HI801_RS00545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HI801_RS00560	COG1832	CoA-binding protein
HI801_RS00580	COG0625	glutathione transferase activity
HI801_RS00610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HI801_RS00615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HI801_RS00620	COG0506	proline dehydrogenase activity
HI801_RS00620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HI801_RS00620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HI801_RS00625	COG0683	leucine binding
HI801_RS00635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HI801_RS00640	COG1297	OPT oligopeptide transporter protein
HI801_RS00645	COG1760	l-serine dehydratase
HI801_RS00650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HI801_RS00650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HI801_RS00655	COG0509	glycine decarboxylation via glycine cleavage system
HI801_RS00660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HI801_RS00680	COG0210	DNA helicase
HI801_RS00690	COG2197	response regulator
HI801_RS00695	COG3916	Acyl-homoserine-lactone synthase
HI801_RS00705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HI801_RS00710	COG2084	Dehydrogenase
HI801_RS00715	COG3622	Belongs to the hyi family
HI801_RS00720	COG3960	tartronate-semialdehyde synthase activity
HI801_RS00725	COG0583	DNA-binding transcription factor activity
HI801_RS00740	COG1739	Uncharacterized protein family UPF0029
HI801_RS00750	COG1301	dicarboxylic acid transport
HI801_RS00755	COG4266	Belongs to the allantoicase family
HI801_RS00770	COG3385	transposase activity
HI801_RS00800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI801_RS00815	COG0792	nuclease activity
HI801_RS00830	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI801_RS00840	COG4654	Cytochrome c, class I
HI801_RS00865	COG2010	Cytochrome c
HI801_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI801_RS00875	COG0737	Belongs to the 5'-nucleotidase family
HI801_RS00885	COG3039	Transposase
HI801_RS00945	COG3311	Transcriptional regulator
HI801_RS01015	COG3609	addiction module antidote protein, CC2985 family
HI801_RS01035	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HI801_RS01135	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI801_RS01215	COG4372	Transposase
HI801_RS01245	COG3210	domain, Protein
HI801_RS01255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS01270	COG3039	Transposase
HI801_RS01280	COG0493	'glutamate synthase
HI801_RS01305	COG0457	Tetratricopeptide repeat
HI801_RS01320	COG0529	Catalyzes the synthesis of activated sulfate
HI801_RS01335	COG3039	Transposase
HI801_RS01340	COG3385	transposase activity
HI801_RS01345	COG1278	Cold shock
HI801_RS01375	COG3039	Transposase
HI801_RS01430	COG5001	Diguanylate cyclase
HI801_RS01430	COG3706	GGDEF domain
HI801_RS01430	COG4251	negative regulation of phosphorylation
HI801_RS01430	COG2203	Gaf domain
HI801_RS01445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI801_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS01465	COG0840	transmembrane signaling receptor activity
HI801_RS01490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI801_RS01500	COG3284	Transcriptional regulator
HI801_RS01505	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS01510	COG4303	Ethanolamine ammonia lyase large subunit
HI801_RS01515	COG4302	ethanolamine ammonia-lyase activity
HI801_RS01520	COG2925	Exonuclease
HI801_RS01640	COG1522	sequence-specific DNA binding
HI801_RS01645	COG1404	Belongs to the peptidase S8 family
HI801_RS01670	COG0475	glutathione-regulated potassium exporter activity
HI801_RS01670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HI801_RS01695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS01705	COG0745	RESPONSE REGULATOR receiver
HI801_RS01905	COG0863	Belongs to the N(4) N(6)-methyltransferase family
HI801_RS01995	COG0582	viral genome integration into host DNA
HI801_RS02030	COG2197	response regulator
HI801_RS02035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HI801_RS02070	COG2814	Major facilitator Superfamily
HI801_RS02075	COG0668	transmembrane transport
HI801_RS02095	COG0745	RESPONSE REGULATOR receiver
HI801_RS02100	COG2205	protein histidine kinase activity
HI801_RS02130	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI801_RS02135	COG2336	PFAM SpoVT AbrB
HI801_RS02155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HI801_RS02170	COG0395	ABC-type sugar transport system, permease component
HI801_RS02180	COG3842	ATPase activity
HI801_RS02195	COG1349	DNA-binding transcription factor activity
HI801_RS02245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HI801_RS02265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HI801_RS02270	COG0081	regulation of translation
HI801_RS02275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HI801_RS02280	COG0222	ribosome binding
HI801_RS02285	COG0085	RNA polymerase activity
HI801_RS02290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HI801_RS02295	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HI801_RS02300	COG3234	Protein of unknown function (DUF1175)
HI801_RS02305	COG2373	Large extracellular alpha-helical protein
HI801_RS02310	COG5445	Predicted secreted protein (DUF2300)
HI801_RS02315	COG4676	Protein conserved in bacteria
HI801_RS02320	COG4676	Protein conserved in bacteria
HI801_RS02330	COG0514	ATP-dependent DNA helicase (RecQ)
HI801_RS02335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HI801_RS02340	COG0049	tRNA binding
HI801_RS02345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HI801_RS02350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HI801_RS02355	COG0051	transcription antitermination factor activity, RNA binding
HI801_RS02360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HI801_RS02365	COG0088	Forms part of the polypeptide exit tunnel
HI801_RS02370	COG0089	rRNA binding
HI801_RS02375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HI801_RS02380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HI801_RS02385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HI801_RS02390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HI801_RS02395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HI801_RS02400	COG0255	Belongs to the universal ribosomal protein uL29 family
HI801_RS02405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HI801_RS02410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HI801_RS02415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HI801_RS02420	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HI801_RS02425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HI801_RS02430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HI801_RS02435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HI801_RS02440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HI801_RS02445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HI801_RS02450	COG1841	ribosomal large subunit assembly
HI801_RS02455	COG0200	Binds to the 23S rRNA
HI801_RS02460	COG0201	protein transport
HI801_RS02465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HI801_RS02470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HI801_RS02475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HI801_RS02480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HI801_RS02485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HI801_RS02490	COG0202	RNA polymerase activity
HI801_RS02495	COG0203	ribosomal protein L17
HI801_RS02505	COG4232	protein-disulfide reductase activity
HI801_RS02515	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HI801_RS02525	COG1333	cytochrome c biogenesis protein
HI801_RS02530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HI801_RS02550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HI801_RS02555	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HI801_RS02570	COG1965	Belongs to the frataxin family
HI801_RS02575	COG3385	transposase activity
HI801_RS02610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HI801_RS02615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HI801_RS02620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HI801_RS02625	COG3047	cAMP biosynthetic process
HI801_RS02635	COG0067	glutamate synthase
HI801_RS02635	COG0069	glutamate synthase activity
HI801_RS02635	COG0070	glutamate synthase
HI801_RS02650	COG1127	ABC transporter
HI801_RS02655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HI801_RS02660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HI801_RS02680	COG1131	(ABC) transporter
HI801_RS02685	COG0842	Transport permease protein
HI801_RS02695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HI801_RS02700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HI801_RS02705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HI801_RS02710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HI801_RS02715	COG0131	Imidazoleglycerol-phosphate dehydratase
HI801_RS02720	COG2095	MarC family integral membrane protein
HI801_RS02725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HI801_RS02730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HI801_RS02735	COG0107	imidazoleglycerol-phosphate synthase activity
HI801_RS02740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HI801_RS02745	COG0140	phosphoribosyl-ATP diphosphatase activity
HI801_RS02755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HI801_RS02760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HI801_RS02765	COG0805	protein transport
HI801_RS02770	COG3842	ATPase activity
HI801_RS02780	COG1840	ABC-type Fe3 transport system, periplasmic component
HI801_RS02785	COG0642	Histidine kinase
HI801_RS02800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS02805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI801_RS02810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HI801_RS02815	COG1970	mechanosensitive ion channel activity
HI801_RS02820	COG0723	plastoquinol--plastocyanin reductase activity
HI801_RS02825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HI801_RS02830	COG2857	Cytochrome c1
HI801_RS02835	COG0625	glutathione transferase activity
HI801_RS02840	COG2969	positive regulation of protein catabolic process
HI801_RS02950	COG3093	addiction module antidote protein HigA
HI801_RS02975	COG3039	Transposase
HI801_RS02990	COG0405	Gamma-glutamyltransferase
HI801_RS02995	COG4774	siderophore transport
HI801_RS03000	COG3712	iron ion homeostasis
HI801_RS03010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HI801_RS03025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HI801_RS03030	COG0488	(ABC) transporter
HI801_RS03050	COG3416	Protein conserved in bacteria
HI801_RS03050	COG2943	transferase activity, transferring hexosyl groups
HI801_RS03055	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI801_RS03075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HI801_RS03080	COG2890	protein-(glutamine-N5) methyltransferase activity
HI801_RS03090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HI801_RS03095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HI801_RS03105	COG0012	GTP binding
HI801_RS03130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI801_RS03140	COG0604	alcohol dehydrogenase
HI801_RS03150	COG1289	transmembrane transporter activity
HI801_RS03165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HI801_RS03175	COG0134	indole-3-glycerol-phosphate synthase activity
HI801_RS03180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI801_RS03190	COG0512	Glutamine amidotransferase of anthranilate synthase
HI801_RS03200	COG0546	phosphoglycolate phosphatase activity
HI801_RS03205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HI801_RS03210	COG2967	ApaG domain
HI801_RS03230	COG2050	protein possibly involved in aromatic compounds catabolism
HI801_RS03235	COG1024	Enoyl-CoA hydratase
HI801_RS03240	COG1024	Enoyl-CoA hydratase
HI801_RS03270	COG1473	amidohydrolase
HI801_RS03275	COG0747	negative chemotaxis
HI801_RS03280	COG0601	transmembrane transport
HI801_RS03285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HI801_RS03290	COG0444	Belongs to the ABC transporter superfamily
HI801_RS03295	COG4608	Belongs to the ABC transporter superfamily
HI801_RS03305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HI801_RS03305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HI801_RS03310	COG1105	Belongs to the carbohydrate kinase PfkB family
HI801_RS03315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HI801_RS03315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HI801_RS03320	COG1609	Transcriptional regulator
HI801_RS03325	COG0243	molybdopterin cofactor binding
HI801_RS03335	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS03340	COG0477	Major facilitator Superfamily
HI801_RS03345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS03350	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HI801_RS03355	COG2001	Belongs to the MraZ family
HI801_RS03360	COG0275	rRNA processing
HI801_RS03375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HI801_RS03380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HI801_RS03385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HI801_RS03390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HI801_RS03400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HI801_RS03405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HI801_RS03410	COG1181	Belongs to the D-alanine--D-alanine ligase family
HI801_RS03415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HI801_RS03430	COG0678	peroxiredoxin activity
HI801_RS03435	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HI801_RS03445	COG0739	heme binding
HI801_RS03450	COG0653	protein targeting
HI801_RS03455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HI801_RS03465	COG0494	nUDIX hydrolase
HI801_RS03470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HI801_RS03475	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HI801_RS03480	COG0237	dephospho-CoA kinase activity
HI801_RS03490	COG1459	type II secretion system
HI801_RS03500	COG4536	flavin adenine dinucleotide binding
HI801_RS03510	COG0142	geranyltranstransferase activity
HI801_RS03515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HI801_RS03520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HI801_RS03525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HI801_RS03530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HI801_RS03540	COG0494	nUDIX hydrolase
HI801_RS03545	COG0442	prolyl-tRNA aminoacylation
HI801_RS03550	COG0741	lytic transglycosylase activity
HI801_RS03560	COG2095	MarC family integral membrane protein
HI801_RS03570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HI801_RS03595	COG3023	N-Acetylmuramoyl-L-alanine amidase
HI801_RS03630	COG3039	Transposase
HI801_RS03675	COG1522	sequence-specific DNA binding
HI801_RS03685	COG0840	transmembrane signaling receptor activity
HI801_RS03720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI801_RS03725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HI801_RS03735	COG2264	protein methyltransferase activity
HI801_RS03745	COG0511	ligase activity, forming carbon-carbon bonds
HI801_RS03750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HI801_RS03755	COG3118	belongs to the thioredoxin family
HI801_RS03765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HI801_RS03770	COG3150	esterase
HI801_RS03775	COG3161	chorismate lyase activity
HI801_RS03780	COG0557	exoribonuclease II activity
HI801_RS03790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HI801_RS03795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HI801_RS03810	COG0284	orotidine-5'-phosphate decarboxylase activity
HI801_RS03820	COG1058	Belongs to the CinA family
HI801_RS03820	COG1546	Belongs to the CinA family
HI801_RS03825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HI801_RS03835	COG0280	phosphate acetyltransferase
HI801_RS03835	COG0281	malic enzyme
HI801_RS03855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HI801_RS03865	COG0583	DNA-binding transcription factor activity
HI801_RS03870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS03885	COG1129	ABC transporter
HI801_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS03910	COG0800	Aldolase
HI801_RS03915	COG4948	Mandelate Racemase Muconate Lactonizing
HI801_RS03920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HI801_RS03925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HI801_RS03930	COG0583	DNA-binding transcription factor activity
HI801_RS03935	COG0735	belongs to the Fur family
HI801_RS03940	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HI801_RS03945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HI801_RS03950	COG0495	leucyl-tRNA aminoacylation
HI801_RS03960	COG1466	dna polymerase III delta subunit
HI801_RS03965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HI801_RS03980	COG2204	response regulator
HI801_RS03985	COG4191	Histidine kinase
HI801_RS03990	COG4191	Histidine kinase
HI801_RS04015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HI801_RS04055	COG0482	sulfurtransferase activity
HI801_RS04060	COG0069	glutamate synthase activity
HI801_RS04065	COG0625	glutathione transferase activity
HI801_RS04075	COG3038	cytochrome b561
HI801_RS04080	COG2353	YceI-like domain
HI801_RS04085	COG2353	YceI-like domain
HI801_RS04090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HI801_RS04095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HI801_RS04100	COG1862	Preprotein translocase
HI801_RS04105	COG0343	queuine tRNA-ribosyltransferase activity
HI801_RS04110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HI801_RS04115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HI801_RS04155	COG1522	sequence-specific DNA binding
HI801_RS04160	COG1473	amidohydrolase
HI801_RS04165	COG1819	glycosyl
HI801_RS04190	COG4372	Transposase
HI801_RS04220	COG1278	Cold shock
HI801_RS04305	COG0783	Belongs to the Dps family
HI801_RS04310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HI801_RS04370	COG0386	Belongs to the glutathione peroxidase family
HI801_RS04390	COG1346	cytolysis
HI801_RS04395	COG1380	Effector of murein hydrolase LrgA
HI801_RS04400	COG0247	lactate metabolic process
HI801_RS04405	COG0277	FAD linked oxidase domain protein
HI801_RS04410	COG0277	FAD linked oxidase domain protein
HI801_RS04415	COG0583	DNA-binding transcription factor activity
HI801_RS04420	COG0277	FAD linked oxidase domain protein
HI801_RS04425	COG2096	Adenosyltransferase
HI801_RS04430	COG0668	transmembrane transport
HI801_RS04440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HI801_RS04445	COG0312	modulator of DNA gyrase
HI801_RS04450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HI801_RS04460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HI801_RS04475	COG1404	Belongs to the peptidase S8 family
HI801_RS04485	COG0497	DNA recombination
HI801_RS04490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HI801_RS04495	COG1420	regulation of RNA biosynthetic process
HI801_RS04505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HI801_RS04510	COG2986	histidine ammonia-lyase
HI801_RS04515	COG0010	Belongs to the arginase family
HI801_RS04520	COG1228	amidohydrolase
HI801_RS04525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HI801_RS04540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HI801_RS04550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HI801_RS04555	COG0443	Heat shock 70 kDa protein
HI801_RS04560	COG0484	heat shock protein binding
HI801_RS04565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HI801_RS04565	COG0512	Glutamine amidotransferase of anthranilate synthase
HI801_RS04570	COG1122	ATPase activity
HI801_RS04575	COG4662	Binding-protein-dependent transport system inner membrane component
HI801_RS04580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HI801_RS04590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HI801_RS04605	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HI801_RS04610	COG0628	permease
HI801_RS04615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HI801_RS04630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HI801_RS04630	COG2169	Transcriptional regulator
HI801_RS04650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HI801_RS04650	COG2169	Transcriptional regulator
HI801_RS04655	COG0456	acetyltransferase
HI801_RS04660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HI801_RS04665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HI801_RS04670	COG3008	intermembrane lipid transfer
HI801_RS04685	COG0586	Pfam SNARE associated Golgi protein
HI801_RS04695	COG0728	peptidoglycan biosynthetic process
HI801_RS04700	COG0268	Binds directly to 16S ribosomal RNA
HI801_RS04710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HI801_RS04720	COG0137	argininosuccinate synthase activity
HI801_RS04725	COG3123	guanosine phosphorylase activity
HI801_RS04735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HI801_RS04740	COG1666	GTP binding
HI801_RS04750	COG2366	antibiotic biosynthetic process
HI801_RS04755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HI801_RS04765	COG4974	Belongs to the 'phage' integrase family
HI801_RS04780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HI801_RS04785	COG0802	atpase or kinase
HI801_RS04790	COG0860	N-Acetylmuramoyl-L-alanine amidase
HI801_RS04800	COG0583	DNA-binding transcription factor activity
HI801_RS04820	COG0563	adenylate kinase activity
HI801_RS04825	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HI801_RS04830	COG2835	tetraacyldisaccharide 4'-kinase activity
HI801_RS04835	COG1663	tetraacyldisaccharide 4'-kinase activity
HI801_RS04845	COG0811	peptide transport
HI801_RS04850	COG1570	exodeoxyribonuclease VII activity
HI801_RS04855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HI801_RS04895	COG2610	gluconate transmembrane transporter activity
HI801_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS04970	COG2321	neutral zinc metallopeptidase
HI801_RS04985	COG2259	Doxx family
HI801_RS04995	COG0583	DNA-binding transcription factor activity
HI801_RS05000	COG0583	DNA-binding transcription factor activity
HI801_RS05055	COG1278	Cold shock
HI801_RS05060	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HI801_RS05065	COG0542	response to heat
HI801_RS05070	COG0756	dUTP diphosphatase activity
HI801_RS05075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HI801_RS05080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HI801_RS05090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HI801_RS05095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HI801_RS05100	COG0196	riboflavin kinase activity
HI801_RS05105	COG5002	protein histidine kinase activity
HI801_RS05105	COG0784	Response regulator, receiver
HI801_RS05110	COG2197	response regulator
HI801_RS05115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HI801_RS05120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HI801_RS05120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HI801_RS05130	COG3264	Mechanosensitive ion channel
HI801_RS05130	COG1511	domain protein
HI801_RS05140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HI801_RS05150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HI801_RS05155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HI801_RS05160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HI801_RS05165	COG2003	Belongs to the UPF0758 family
HI801_RS05170	COG1047	Peptidyl-prolyl cis-trans
HI801_RS05175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HI801_RS05210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HI801_RS05250	COG2084	Dehydrogenase
HI801_RS05260	COG0583	DNA-binding transcription factor activity
HI801_RS05270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI801_RS05280	COG0175	sulfate reduction
HI801_RS05290	COG2895	sulfate adenylyltransferase (ATP) activity
HI801_RS05320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HI801_RS05335	COG0129	dihydroxy-acid dehydratase activity
HI801_RS05340	COG0583	DNA-binding transcription factor activity
HI801_RS05345	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HI801_RS05375	COG4206	TonB-dependent receptor
HI801_RS05385	COG1120	ATPase activity
HI801_RS05395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HI801_RS05400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HI801_RS05410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HI801_RS05420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HI801_RS05430	COG1492	cobalamin metabolic process
HI801_RS05450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HI801_RS05455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HI801_RS05470	COG2911	Protein conserved in bacteria
HI801_RS05480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI801_RS05480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI801_RS05485	COG2885	chlorophyll binding
HI801_RS05485	COG3047	cAMP biosynthetic process
HI801_RS05490	COG0489	protein tyrosine kinase activity
HI801_RS05520	COG0243	molybdopterin cofactor binding
HI801_RS05520	COG3383	formate dehydrogenase (NAD+) activity
HI801_RS05525	COG0437	4 iron, 4 sulfur cluster binding
HI801_RS05545	COG2032	superoxide dismutase activity
HI801_RS05550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HI801_RS05555	COG0717	Belongs to the dCTP deaminase family
HI801_RS05560	COG1982	Orn Lys Arg decarboxylase major
HI801_RS05570	COG3039	Transposase
HI801_RS05595	COG0165	Argininosuccinate lyase
HI801_RS05620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HI801_RS05625	COG0181	hydroxymethylbilane synthase activity
HI801_RS05650	COG2271	Major facilitator Superfamily
HI801_RS05665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HI801_RS05700	COG0492	ferredoxin-NADP+ reductase activity
HI801_RS05705	COG1674	ftsk spoiiie
HI801_RS05710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HI801_RS05720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HI801_RS05725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HI801_RS05735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HI801_RS05810	COG4983	Phage plasmid primase, P4 family domain protein
HI801_RS05845	COG3039	Transposase
HI801_RS05870	COG4372	Transposase
HI801_RS05890	COG0745	RESPONSE REGULATOR receiver
HI801_RS05895	COG0840	transmembrane signaling receptor activity
HI801_RS05900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HI801_RS05920	COG5377	YqaJ viral recombinase family
HI801_RS05940	COG0251	oxidation-reduction process
HI801_RS06000	COG2197	response regulator
HI801_RS06055	COG2165	general secretion pathway protein
HI801_RS06125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI801_RS06175	COG1253	flavin adenine dinucleotide binding
HI801_RS06230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS06245	COG0765	amino acid transport
HI801_RS06250	COG0765	amino acid transport
HI801_RS06255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI801_RS06265	COG1414	Transcriptional regulator
HI801_RS06275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HI801_RS06280	COG0183	Belongs to the thiolase family
HI801_RS06290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HI801_RS06295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HI801_RS06310	COG0411	ABC transporter
HI801_RS06320	COG0683	leucine binding
HI801_RS06335	COG2342	PFAM TM1410 hypothetical-related protein
HI801_RS06345	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HI801_RS06360	COG0525	valine-tRNA ligase activity
HI801_RS06365	COG0210	DNA helicase
HI801_RS06375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HI801_RS06385	COG1611	Belongs to the LOG family
HI801_RS06390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI801_RS06390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI801_RS06395	COG1252	NADH dehydrogenase
HI801_RS06400	COG0412	Dienelactone hydrolase
HI801_RS06410	COG3385	transposase activity
HI801_RS06430	COG1722	exodeoxyribonuclease VII activity
HI801_RS06435	COG0142	geranyltranstransferase activity
HI801_RS06440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HI801_RS06445	COG1469	GTP cyclohydrolase I activity
HI801_RS06450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HI801_RS06455	COG2081	HI0933 family
HI801_RS06460	COG1610	YqeY-like protein
HI801_RS06480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI801_RS06490	COG0426	domain, Protein
HI801_RS06490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HI801_RS06495	COG0513	Belongs to the DEAD box helicase family
HI801_RS06500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI801_RS06505	COG0583	DNA-binding transcription factor activity
HI801_RS06510	COG1741	Belongs to the pirin family
HI801_RS06550	COG1132	(ABC) transporter
HI801_RS06570	COG1530	ribonuclease E activity
HI801_RS06575	COG0424	maF-like protein
HI801_RS06580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HI801_RS06585	COG0799	negative regulation of ribosome biogenesis
HI801_RS06595	COG0408	coproporphyrinogen oxidase activity
HI801_RS06600	COG0151	Belongs to the GarS family
HI801_RS06605	COG0217	transcriptional regulatory protein
HI801_RS06610	COG0433	COG0433 Predicted ATPase
HI801_RS06615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HI801_RS06620	COG0697	spore germination
HI801_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS06630	COG1803	Methylglyoxal synthase
HI801_RS06690	COG1129	ABC transporter
HI801_RS06695	COG2814	Major facilitator Superfamily
HI801_RS06700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HI801_RS06705	COG1984	allophanate hydrolase subunit 2
HI801_RS06710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HI801_RS06725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HI801_RS06730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HI801_RS06745	COG1234	tRNA 3'-trailer cleavage
HI801_RS06755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HI801_RS06760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HI801_RS06765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HI801_RS06775	COG0515	serine threonine protein kinase
HI801_RS06775	COG4991	sh3 domain protein
HI801_RS06775	COG3064	Membrane
HI801_RS06780	COG1561	YicC-like family, N-terminal region
HI801_RS06785	COG0194	GDP metabolic process
HI801_RS06790	COG1758	RNA polymerase activity
HI801_RS06795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HI801_RS06825	COG1652	LysM domain
HI801_RS06835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI801_RS06860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HI801_RS06865	COG3842	ATPase activity
HI801_RS06905	COG0246	Mannitol dehydrogenase
HI801_RS06910	COG1070	Carbohydrate kinase
HI801_RS06915	COG2390	Transcriptional regulator
HI801_RS06925	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HI801_RS06930	COG0308	aminopeptidase N
HI801_RS06940	COG0280	phosphate acetyltransferase
HI801_RS06940	COG0281	malic enzyme
HI801_RS06950	COG3648	Uricase
HI801_RS06950	COG3195	allantoin biosynthetic process
HI801_RS06965	COG2233	PERMEase
HI801_RS06975	COG2351	hydroxyisourate hydrolase activity
HI801_RS06990	COG3039	Transposase
HI801_RS07000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS07005	COG2271	Major facilitator Superfamily
HI801_RS07010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI801_RS07015	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS07025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS07035	COG1126	abc transporter atp-binding protein
HI801_RS07040	COG0765	amino acid transport
HI801_RS07045	COG0765	amino acid transport
HI801_RS07055	COG2186	Transcriptional regulator
HI801_RS07065	COG2119	membrane
HI801_RS07070	COG0402	S-adenosylhomocysteine deaminase activity
HI801_RS07075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HI801_RS07085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HI801_RS07110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HI801_RS07135	COG1309	transcriptional regulator
HI801_RS07145	COG0438	transferase activity, transferring glycosyl groups
HI801_RS07180	COG0028	Belongs to the TPP enzyme family
HI801_RS07190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HI801_RS07195	COG0688	phosphatidylethanolamine metabolic process
HI801_RS07200	COG1183	phosphatidylcholine synthase activity
HI801_RS07205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HI801_RS07215	COG0683	leucine binding
HI801_RS07220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HI801_RS07225	COG1185	polyribonucleotide nucleotidyltransferase activity
HI801_RS07240	COG0149	triose-phosphate isomerase activity
HI801_RS07245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HI801_RS07255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI801_RS07260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI801_RS07265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI801_RS07270	COG0649	NAD binding
HI801_RS07285	COG1034	ATP synthesis coupled electron transport
HI801_RS07290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HI801_RS07295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI801_RS07305	COG0713	ATP synthesis coupled electron transport
HI801_RS07320	COG1007	ATP synthesis coupled electron transport
HI801_RS07340	COG1960	acyl-CoA dehydrogenase activity
HI801_RS07345	COG1960	acyl-CoA dehydrogenase activity
HI801_RS07350	COG2030	dehydratase
HI801_RS07350	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS07385	COG0829	nickel cation binding
HI801_RS07390	COG0831	urea catabolic process
HI801_RS07400	COG0832	Belongs to the urease beta subunit family
HI801_RS07405	COG0804	urea catabolic process
HI801_RS07410	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HI801_RS07415	COG0830	nickel cation binding
HI801_RS07420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HI801_RS07450	COG0625	glutathione transferase activity
HI801_RS07455	COG1960	acyl-CoA dehydrogenase activity
HI801_RS07485	COG1024	Enoyl-CoA hydratase
HI801_RS07490	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI801_RS07495	COG0625	glutathione transferase activity
HI801_RS07500	COG0436	Aminotransferase
HI801_RS07510	COG3022	response to hydroperoxide
HI801_RS07515	COG2866	Carboxypeptidase
HI801_RS07525	COG0747	negative chemotaxis
HI801_RS07540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HI801_RS07565	COG0039	L-malate dehydrogenase activity
HI801_RS07570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI801_RS07580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HI801_RS07585	COG1053	succinate dehydrogenase
HI801_RS07590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HI801_RS07595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HI801_RS07600	COG0372	Belongs to the citrate synthase family
HI801_RS07605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HI801_RS07610	COG0066	3-isopropylmalate dehydratase activity
HI801_RS07615	COG0473	3-isopropylmalate dehydrogenase activity
HI801_RS07635	COG0101	tRNA pseudouridine synthase activity
HI801_RS07640	COG0135	phosphoribosylanthranilate isomerase activity
HI801_RS07645	COG0133	tryptophan synthase activity
HI801_RS07655	COG0159	tryptophan synthase activity
HI801_RS07660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HI801_RS07665	COG0285	dihydrofolate synthase activity
HI801_RS07685	COG0842	Transport permease protein
HI801_RS07690	COG1131	(ABC) transporter
HI801_RS07720	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HI801_RS07765	COG1301	dicarboxylic acid transport
HI801_RS07770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HI801_RS07785	COG0697	spore germination
HI801_RS07790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI801_RS07795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HI801_RS07810	COG3501	Rhs element vgr protein
HI801_RS07830	COG4695	Portal protein
HI801_RS07900	COG3039	Transposase
HI801_RS08060	COG2197	response regulator
HI801_RS08065	COG0840	transmembrane signaling receptor activity
HI801_RS08105	COG0747	negative chemotaxis
HI801_RS08120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HI801_RS08125	COG0601	transmembrane transport
HI801_RS08130	COG2072	flavoprotein involved in K transport
HI801_RS08175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HI801_RS08220	COG0656	L-ascorbic acid biosynthetic process
HI801_RS08225	COG2304	oxidoreductase activity
HI801_RS08240	COG0589	response to stress
HI801_RS08280	COG0328	RNA-DNA hybrid ribonuclease activity
HI801_RS08285	COG2226	methyltransferase
HI801_RS08290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI801_RS08295	COG1388	LysM domain
HI801_RS08295	COG0741	lytic transglycosylase activity
HI801_RS08300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI801_RS08305	COG0505	Belongs to the CarA family
HI801_RS08315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HI801_RS08320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HI801_RS08330	COG1534	Rna-binding protein
HI801_RS08335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HI801_RS08340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HI801_RS08345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HI801_RS08350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HI801_RS08355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HI801_RS08360	COG0573	inorganic phosphate transmembrane transporter activity
HI801_RS08365	COG0581	inorganic phosphate transmembrane transporter activity
HI801_RS08370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HI801_RS08380	COG0745	RESPONSE REGULATOR receiver
HI801_RS08395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HI801_RS08400	COG0248	Ppx GppA phosphatase
HI801_RS08430	COG0730	response to heat
HI801_RS08440	COG0640	Transcriptional regulator
HI801_RS08450	COG3300	MHYT domain
HI801_RS08450	COG5001	Diguanylate cyclase
HI801_RS08485	COG0277	FAD linked oxidase domain protein
HI801_RS08500	COG1295	ribonuclease BN
HI801_RS08525	COG0477	Major facilitator Superfamily
HI801_RS08530	COG0545	Peptidyl-prolyl cis-trans isomerase
HI801_RS08535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HI801_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS08550	COG4566	intracellular signal transduction
HI801_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS08575	COG0251	oxidation-reduction process
HI801_RS08580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HI801_RS08590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HI801_RS08595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HI801_RS08600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HI801_RS08605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HI801_RS08610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HI801_RS08615	COG0072	phenylalanine-tRNA ligase activity
HI801_RS08615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI801_RS08620	COG0776	regulation of translation
HI801_RS08650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HI801_RS08655	COG0531	amino acid
HI801_RS08675	COG1846	Transcriptional regulator
HI801_RS08685	COG0402	S-adenosylhomocysteine deaminase activity
HI801_RS08690	COG0339	signal peptide processing
HI801_RS08695	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HI801_RS08700	COG4566	intracellular signal transduction
HI801_RS08715	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HI801_RS08720	COG0508	dehydrogenase complex catalyzes the overall conversion of
HI801_RS08730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HI801_RS08745	COG0123	including yeast histone deacetylase and acetoin utilization protein
HI801_RS08770	COG1414	Transcriptional regulator
HI801_RS08800	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HI801_RS08805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HI801_RS08825	COG0167	dihydroorotate dehydrogenase activity
HI801_RS08835	COG3158	transport of potassium into the cell
HI801_RS08845	COG2183	response to ionizing radiation
HI801_RS08860	COG1199	ATP-dependent helicase activity
HI801_RS08870	COG0564	pseudouridine synthase activity
HI801_RS08885	COG3243	poly(R)-hydroxyalkanoic acid synthase
HI801_RS08890	COG0183	Belongs to the thiolase family
HI801_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS08905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HI801_RS08910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HI801_RS08915	COG0183	Belongs to the thiolase family
HI801_RS08930	COG0560	Phosphoserine phosphatase
HI801_RS08940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HI801_RS08945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HI801_RS08950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HI801_RS08955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HI801_RS08960	COG0450	alkyl hydroperoxide reductase
HI801_RS08970	COG0745	RESPONSE REGULATOR receiver
HI801_RS08990	COG1562	ergosterol biosynthetic process
HI801_RS08995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS09010	COG0582	viral genome integration into host DNA
HI801_RS09025	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HI801_RS09165	COG4386	tail sheath protein
HI801_RS09190	COG4228	DNA circulation
HI801_RS09205	COG4381	Mu-like prophage protein gp46
HI801_RS09265	COG1652	LysM domain
HI801_RS09280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS09280	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HI801_RS09285	COG0544	peptidyl-prolyl cis-trans isomerase activity
HI801_RS09290	COG0740	serine-type endopeptidase activity
HI801_RS09295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HI801_RS09300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HI801_RS09305	COG0776	regulation of translation
HI801_RS09320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS09325	COG3385	transposase activity
HI801_RS09340	COG4181	ATPase activity
HI801_RS09345	COG0166	Belongs to the GPI family
HI801_RS09350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HI801_RS09360	COG0047	phosphoribosylformylglycinamidine synthase activity
HI801_RS09360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HI801_RS09385	COG0535	radical SAM domain protein
HI801_RS09405	COG0583	DNA-binding transcription factor activity
HI801_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS09420	COG1176	ABC-type spermidine putrescine transport system, permease component I
HI801_RS09430	COG3842	ATPase activity
HI801_RS09435	COG0642	Histidine kinase
HI801_RS09450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HI801_RS09475	COG1126	abc transporter atp-binding protein
HI801_RS09480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS09490	COG2917	probably involved in intracellular septation
HI801_RS09495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HI801_RS09500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HI801_RS09505	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS09515	COG0559	Belongs to the binding-protein-dependent transport system permease family
HI801_RS09545	COG0833	amino acid
HI801_RS09550	COG0833	amino acid
HI801_RS09560	COG1335	isochorismatase
HI801_RS09565	COG0183	Belongs to the thiolase family
HI801_RS09570	COG1960	acyl-CoA dehydrogenase activity
HI801_RS09575	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS09590	COG2130	NADP-dependent
HI801_RS09610	COG0596	Alpha beta hydrolase
HI801_RS09660	COG2831	hemolysin activation secretion protein
HI801_RS09680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HI801_RS09685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HI801_RS09690	COG0470	DNA polymerase III
HI801_RS09700	COG0084	hydrolase, TatD family'
HI801_RS09710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HI801_RS09715	COG1609	Transcriptional regulator
HI801_RS09720	COG1840	ABC-type Fe3 transport system, periplasmic component
HI801_RS09730	COG4208	sulfate ABC transporter
HI801_RS09735	COG3842	ATPase activity
HI801_RS09740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI801_RS09745	COG3023	N-Acetylmuramoyl-L-alanine amidase
HI801_RS09780	COG0038	chloride channel
HI801_RS09785	COG2226	methyltransferase
HI801_RS09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS09795	COG2226	methyltransferase
HI801_RS09795	COG3433	isochorismatase activity
HI801_RS09800	COG4771	TonB-dependent receptor
HI801_RS09820	COG3433	isochorismatase activity
HI801_RS09820	COG2226	methyltransferase
HI801_RS09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS09835	COG2201	protein-glutamate methylesterase activity
HI801_RS09840	COG0456	acetyltransferase
HI801_RS09885	COG0179	Fumarylacetoacetate (FAA) hydrolase
HI801_RS09930	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HI801_RS09955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HI801_RS09965	COG3039	Transposase
HI801_RS10045	COG0415	Belongs to the DNA photolyase family
HI801_RS10055	COG0459	protein refolding
HI801_RS10105	COG0071	Belongs to the small heat shock protein (HSP20) family
HI801_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI801_RS10135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI801_RS10180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HI801_RS10185	COG0156	8-amino-7-oxononanoate synthase activity
HI801_RS10220	COG3045	CreA protein
HI801_RS10260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HI801_RS10275	COG0840	transmembrane signaling receptor activity
HI801_RS10285	COG3387	PFAM Glycoside hydrolase 15-related
HI801_RS10310	COG0488	(ABC) transporter
HI801_RS10315	COG1619	proteins homologs of microcin C7 resistance protein MccF
HI801_RS10325	COG0720	synthase
HI801_RS10330	COG0602	queuosine metabolic process
HI801_RS10345	COG3550	peptidyl-serine autophosphorylation
HI801_RS10365	COG3485	protocatechuate 3,4-dioxygenase
HI801_RS10370	COG3485	protocatechuate 3,4-dioxygenase
HI801_RS10375	COG0583	DNA-binding transcription factor activity
HI801_RS10420	COG0519	Catalyzes the synthesis of GMP from XMP
HI801_RS10420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HI801_RS10435	COG0697	spore germination
HI801_RS10445	COG2914	Belongs to the UPF0125 (RnfH) family
HI801_RS10450	COG2867	negative regulation of translational initiation
HI801_RS10455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HI801_RS10460	COG0330	HflC and HflK could
HI801_RS10475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HI801_RS10480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HI801_RS10485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HI801_RS10490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI801_RS10495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI801_RS10500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HI801_RS10505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI801_RS10520	COG0750	zinc metalloprotease
HI801_RS10525	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HI801_RS10530	COG0575	Belongs to the CDS family
HI801_RS10535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HI801_RS10540	COG0233	cytoplasmic translational termination
HI801_RS10545	COG0528	UMP kinase activity
HI801_RS10550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HI801_RS10555	COG0052	Belongs to the universal ribosomal protein uS2 family
HI801_RS10560	COG0024	Methionine aminopeptidase
HI801_RS10565	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HI801_RS10570	COG1187	pseudouridine synthase activity
HI801_RS10580	COG0242	peptide deformylase activity
HI801_RS10585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HI801_RS10600	COG0596	Alpha beta hydrolase
HI801_RS10615	COG2171	N-acyltransferase activity
HI801_RS10625	COG1393	Belongs to the ArsC family
HI801_RS10630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI801_RS10640	COG2890	protein-(glutamine-N5) methyltransferase activity
HI801_RS10645	COG0302	gtp cyclohydrolase
HI801_RS10675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HI801_RS10680	COG0601	transmembrane transport
HI801_RS10685	COG0747	negative chemotaxis
HI801_RS10690	COG4172	Belongs to the ABC transporter superfamily
HI801_RS10705	COG0488	(ABC) transporter
HI801_RS10715	COG1683	Conserved Protein
HI801_RS10720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HI801_RS10730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HI801_RS10735	COG0477	Major facilitator Superfamily
HI801_RS10740	COG1573	uracil-dna glycosylase
HI801_RS10750	COG1214	PFAM Peptidase M22, glycoprotease
HI801_RS10760	COG2814	Major facilitator Superfamily
HI801_RS10770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HI801_RS10780	COG0583	DNA-binding transcription factor activity
HI801_RS10790	COG2224	Isocitrate lyase
HI801_RS10810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI801_RS10825	COG3275	phosphorelay sensor kinase activity
HI801_RS10840	COG0583	DNA-binding transcription factor activity
HI801_RS10845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HI801_RS10850	COG4208	sulfate ABC transporter
HI801_RS10875	COG1116	anion transmembrane transporter activity
HI801_RS10880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI801_RS10885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HI801_RS10890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI801_RS10895	COG0431	NADPH-dependent FMN reductase
HI801_RS10900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HI801_RS10905	COG0542	response to heat
HI801_RS10910	COG3039	Transposase
HI801_RS10920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HI801_RS10925	COG0314	molybdopterin synthase activity
HI801_RS10930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HI801_RS10935	COG0303	'Molybdopterin
HI801_RS10940	COG1573	uracil-dna glycosylase
HI801_RS10955	COG0436	Aminotransferase
HI801_RS10965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HI801_RS10970	COG2076	Multidrug Resistance protein
HI801_RS10975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HI801_RS10990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI801_RS10990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HI801_RS11000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HI801_RS11005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HI801_RS11015	COG0791	NLP P60 protein
HI801_RS11020	COG0306	phosphate transporter
HI801_RS11030	COG0305	Participates in initiation and elongation during chromosome replication
HI801_RS11035	COG0359	binds to the 23S rRNA
HI801_RS11040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HI801_RS11050	COG0360	Binds together with S18 to 16S ribosomal RNA
HI801_RS11065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HI801_RS11075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI801_RS11090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HI801_RS11095	COG1024	Enoyl-CoA hydratase
HI801_RS11120	COG1566	PFAM secretion protein HlyD family protein
HI801_RS11125	COG2814	Major facilitator Superfamily
HI801_RS11130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HI801_RS11135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HI801_RS11140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HI801_RS11145	COG0195	Participates in both transcription termination and antitermination
HI801_RS11145	COG2251	uridine kinase activity
HI801_RS11150	COG0779	Required for maturation of 30S ribosomal subunits
HI801_RS11155	COG1187	pseudouridine synthase activity
HI801_RS11160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HI801_RS11170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HI801_RS11205	COG3278	Belongs to the heme-copper respiratory oxidase family
HI801_RS11215	COG2217	Heavy metal translocating P-type atpase
HI801_RS11225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HI801_RS11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HI801_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
HI801_RS11240	COG0567	Dehydrogenase, E1 component
HI801_RS11245	COG0584	glycerophosphoryl diester phosphodiesterase
HI801_RS11250	COG3842	ATPase activity
HI801_RS11260	COG1175	transmembrane transport
HI801_RS11265	COG1653	transport
HI801_RS11280	COG2204	response regulator
HI801_RS11295	COG0174	glutamine synthetase
HI801_RS11305	COG1546	Belongs to the CinA family
HI801_RS11305	COG1058	Belongs to the CinA family
HI801_RS11330	COG1643	Atp-dependent helicase
HI801_RS11335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HI801_RS11335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HI801_RS11345	COG0673	inositol 2-dehydrogenase activity
HI801_RS11355	COG0673	inositol 2-dehydrogenase activity
HI801_RS11365	COG1082	Xylose isomerase domain protein TIM barrel
HI801_RS11370	COG1172	Belongs to the binding-protein-dependent transport system permease family
HI801_RS11375	COG1129	ABC transporter
HI801_RS11385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI801_RS11390	COG3962	Belongs to the TPP enzyme family
HI801_RS11400	COG3718	enzyme involved in inositol metabolism
HI801_RS11410	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HI801_RS11420	COG1953	Uracil, thiamine, allantoin
HI801_RS11425	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HI801_RS11430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HI801_RS11435	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HI801_RS11440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HI801_RS11445	COG0557	exoribonuclease II activity
HI801_RS11455	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HI801_RS11460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HI801_RS11465	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HI801_RS11475	COG0330	HflC and HflK could
HI801_RS11480	COG0330	HflC and HflK could
HI801_RS11485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HI801_RS11490	COG1923	regulation of RNA biosynthetic process
HI801_RS11495	COG1160	GTP binding
HI801_RS11505	COG2976	Protein conserved in bacteria
HI801_RS11510	COG0124	histidyl-tRNA synthetase
HI801_RS11515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HI801_RS11530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HI801_RS11535	COG0105	UTP biosynthetic process
HI801_RS11545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HI801_RS11565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HI801_RS11570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HI801_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS11575	COG3321	synthase
HI801_RS11575	COG0604	alcohol dehydrogenase
HI801_RS11580	COG1902	pentaerythritol trinitrate reductase activity
HI801_RS11585	COG1309	transcriptional regulator
HI801_RS11590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI801_RS11600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI801_RS11605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI801_RS11620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HI801_RS11625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HI801_RS11640	COG1074	ATP-dependent DNA helicase activity
HI801_RS11655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HI801_RS11660	COG2204	response regulator
HI801_RS11665	COG2197	response regulator
HI801_RS11670	COG3228	Belongs to the MtfA family
HI801_RS11680	COG0254	rRNA binding
HI801_RS11690	COG0534	Mate efflux family protein
HI801_RS11725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI801_RS11730	COG1752	Esterase of the alpha-beta hydrolase superfamily
HI801_RS11735	COG0791	NLP P60 protein
HI801_RS11740	COG4172	Belongs to the ABC transporter superfamily
HI801_RS11745	COG4239	(ABC) transporter, permease
HI801_RS11750	COG4174	ABC transporter (Permease)
HI801_RS11755	COG4166	transmembrane transport
HI801_RS11770	COG0527	aspartate kinase activity
HI801_RS11775	COG0037	tRNA processing
HI801_RS11780	COG0825	malonyl-CoA metabolic process
HI801_RS11785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HI801_RS11790	COG0215	cysteine-tRNA ligase activity
HI801_RS11805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HI801_RS11810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI801_RS11815	COG1045	serine acetyltransferase
HI801_RS11830	COG1396	sequence-specific DNA binding
HI801_RS11840	COG2258	MOSC domain
HI801_RS11850	COG0840	transmembrane signaling receptor activity
HI801_RS11860	COG2814	Major facilitator Superfamily
HI801_RS11865	COG0583	DNA-binding transcription factor activity
HI801_RS11880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HI801_RS11895	COG2850	peptidyl-arginine hydroxylation
HI801_RS11905	COG1234	tRNA 3'-trailer cleavage
HI801_RS11910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HI801_RS11915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI801_RS11925	COG0180	Tryptophanyl-tRNA synthetase
HI801_RS11930	COG1994	Peptidase M50
HI801_RS11935	COG0009	L-threonylcarbamoyladenylate synthase
HI801_RS11940	COG0613	PHP domain protein
HI801_RS11945	COG0492	ferredoxin-NADP+ reductase activity
HI801_RS11960	COG3011	Protein conserved in bacteria
HI801_RS11965	COG2267	carboxylic ester hydrolase activity
HI801_RS11970	COG2833	Protein of unknown function (DUF455)
HI801_RS11980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HI801_RS11990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HI801_RS11995	COG0148	phosphopyruvate hydratase activity
HI801_RS12005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HI801_RS12010	COG0504	CTP synthase activity
HI801_RS12015	COG2267	carboxylic ester hydrolase activity
HI801_RS12035	COG2308	Evidence 4 Homologs of previously reported genes of
HI801_RS12045	COG0084	hydrolase, TatD family'
HI801_RS12050	COG1136	(ABC) transporter
HI801_RS12065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HI801_RS12070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HI801_RS12095	COG2855	membrane
HI801_RS12100	COG0583	DNA-binding transcription factor activity
HI801_RS12140	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI801_RS12140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HI801_RS12175	COG0436	Aminotransferase
HI801_RS12185	COG0583	DNA-binding transcription factor activity
HI801_RS12190	COG2271	Major facilitator Superfamily
HI801_RS12230	COG0625	glutathione transferase activity
HI801_RS12235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS12245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS12255	COG2271	Major facilitator Superfamily
HI801_RS12265	COG2186	Transcriptional regulator
HI801_RS12270	COG3385	transposase activity
HI801_RS12280	COG0745	RESPONSE REGULATOR receiver
HI801_RS12285	COG5002	protein histidine kinase activity
HI801_RS12295	COG0745	RESPONSE REGULATOR receiver
HI801_RS12320	COG0322	excinuclease ABC activity
HI801_RS12330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HI801_RS12340	COG0736	holo-[acyl-carrier-protein] synthase activity
HI801_RS12345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HI801_RS12350	COG1381	Involved in DNA repair and RecF pathway recombination
HI801_RS12355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HI801_RS12360	COG0571	ribonuclease III activity
HI801_RS12370	COG0681	Belongs to the peptidase S26 family
HI801_RS12375	COG0481	GTPase activity
HI801_RS12385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI801_RS12410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI801_RS12415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI801_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS12430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HI801_RS12435	COG0416	fatty acid biosynthetic process
HI801_RS12440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HI801_RS12445	COG1399	metal-binding, possibly nucleic acid-binding protein
HI801_RS12450	COG0424	maF-like protein
HI801_RS12460	COG0616	signal peptide processing
HI801_RS12460	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HI801_RS12470	COG0546	phosphoglycolate phosphatase activity
HI801_RS12480	COG1530	ribonuclease E activity
HI801_RS12485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HI801_RS12490	COG0746	molybdenum cofactor guanylyltransferase activity
HI801_RS12505	COG1322	Protein conserved in bacteria
HI801_RS12510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI801_RS12525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HI801_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS12540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HI801_RS12550	COG3385	transposase activity
HI801_RS12565	COG0443	Heat shock 70 kDa protein
HI801_RS12570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HI801_RS12580	COG0316	Belongs to the HesB IscA family
HI801_RS12585	COG0822	iron-sulfur transferase activity
HI801_RS12590	COG1104	cysteine desulfurase activity
HI801_RS12600	COG1879	ABC-type sugar transport system periplasmic component
HI801_RS12605	COG1129	ABC transporter
HI801_RS12610	COG1172	Belongs to the binding-protein-dependent transport system permease family
HI801_RS12615	COG1609	Transcriptional regulator
HI801_RS12620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI801_RS12630	COG0556	nucleotide-excision repair
HI801_RS12645	COG1309	transcriptional regulator
HI801_RS12650	COG2878	Part of a membrane complex involved in electron transport
HI801_RS12655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HI801_RS12660	COG0778	Nitroreductase
HI801_RS12695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HI801_RS12735	COG0326	Molecular chaperone. Has ATPase activity
HI801_RS12740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI801_RS12745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HI801_RS12750	COG0697	spore germination
HI801_RS12760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI801_RS12765	COG0625	glutathione transferase activity
HI801_RS12780	COG1620	l-lactate permease
HI801_RS12800	COG0741	lytic transglycosylase activity
HI801_RS12850	COG0513	Belongs to the DEAD box helicase family
HI801_RS12855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HI801_RS12865	COG0861	Integral membrane protein TerC family
HI801_RS12875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HI801_RS12885	COG0312	modulator of DNA gyrase
HI801_RS12890	COG3028	Belongs to the UPF0307 family
HI801_RS12895	COG0521	Mo-molybdopterin cofactor biosynthetic process
HI801_RS12900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HI801_RS12905	COG0501	Belongs to the peptidase M48B family
HI801_RS12910	COG1162	GTPase activity
HI801_RS12920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HI801_RS12925	COG0494	nUDIX hydrolase
HI801_RS12930	COG0335	large ribosomal subunit rRNA binding
HI801_RS12935	COG0336	Belongs to the RNA methyltransferase TrmD family
HI801_RS12940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HI801_RS12945	COG0228	four-way junction DNA binding
HI801_RS12980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS12985	COG1960	acyl-CoA dehydrogenase activity
HI801_RS13005	COG2011	ABC-type metal ion transport system permease component
HI801_RS13010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HI801_RS13015	COG0123	including yeast histone deacetylase and acetoin utilization protein
HI801_RS13020	COG2951	lytic endotransglycosylase activity
HI801_RS13035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI801_RS13040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HI801_RS13050	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HI801_RS13060	COG0776	regulation of translation
HI801_RS13070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HI801_RS13075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HI801_RS13080	COG0287	Prephenate dehydrogenase
HI801_RS13085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HI801_RS13090	COG1605	Chorismate mutase
HI801_RS13090	COG0077	Prephenate dehydratase
HI801_RS13095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HI801_RS13120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HI801_RS13195	COG3501	Rhs element vgr protein
HI801_RS13200	COG0583	DNA-binding transcription factor activity
HI801_RS13305	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI801_RS13425	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HI801_RS13540	COG4372	Transposase
HI801_RS13670	COG3039	Transposase
HI801_RS13705	COG3039	Transposase
HI801_RS13720	COG0778	Nitroreductase
HI801_RS13735	COG4305	rare lipoprotein A
HI801_RS13755	COG1280	lysine exporter protein (LysE YggA)
HI801_RS13770	COG0425	Belongs to the sulfur carrier protein TusA family
HI801_RS13785	COG1942	4-Oxalocrotonate Tautomerase
HI801_RS13790	COG0235	Class ii aldolase
HI801_RS13795	COG0477	Major facilitator Superfamily
HI801_RS13810	COG0330	HflC and HflK could
HI801_RS13835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HI801_RS13840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI801_RS13865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI801_RS13895	COG4681	YaeQ
HI801_RS13910	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HI801_RS13920	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS13925	COG3118	belongs to the thioredoxin family
HI801_RS13935	COG2703	oxygen carrier activity
HI801_RS13940	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HI801_RS13945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HI801_RS13950	COG2982	Protein involved in outer membrane biogenesis
HI801_RS13970	COG0259	pyridoxamine-phosphate oxidase activity
HI801_RS13975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI801_RS13985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HI801_RS13990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HI801_RS14000	COG1522	sequence-specific DNA binding
HI801_RS14005	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HI801_RS14015	COG3483	tryptophan 2,3-dioxygenase activity
HI801_RS14025	COG1960	acyl-CoA dehydrogenase activity
HI801_RS14030	COG2252	PERMEase
HI801_RS14035	COG0450	alkyl hydroperoxide reductase
HI801_RS14040	COG4575	ribosome binding
HI801_RS14060	COG1136	(ABC) transporter
HI801_RS14065	COG0390	transport system, permease component
HI801_RS14095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HI801_RS14100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HI801_RS14105	COG0745	RESPONSE REGULATOR receiver
HI801_RS14115	COG3385	transposase activity
HI801_RS14125	COG2391	methyltransferase activity
HI801_RS14130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HI801_RS14145	COG0823	Involved in the tonB-independent uptake of proteins
HI801_RS14165	COG0824	Thioesterase
HI801_RS14170	COG4221	oxidoreductase activity
HI801_RS14175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HI801_RS14180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HI801_RS14245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HI801_RS14245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HI801_RS14260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HI801_RS14265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HI801_RS14285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HI801_RS14315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HI801_RS14320	COG1902	pentaerythritol trinitrate reductase activity
HI801_RS14325	COG1968	undecaprenyl-diphosphatase activity
HI801_RS14345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HI801_RS14350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HI801_RS14350	COG0425	Belongs to the sulfur carrier protein TusA family
HI801_RS14370	COG0859	PFAM glycosyl transferase family 9
HI801_RS14385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HI801_RS14425	COG1088	dTDP-glucose 4,6-dehydratase activity
HI801_RS14430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HI801_RS14445	COG0540	Belongs to the ATCase OTCase family
HI801_RS14450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HI801_RS14455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HI801_RS14460	COG1678	Uncharacterized ACR, COG1678
HI801_RS14465	COG1187	pseudouridine synthase activity
HI801_RS14475	COG0643	Histidine kinase
HI801_RS14475	COG0784	Response regulator, receiver
HI801_RS14475	COG2198	Histidine kinase
HI801_RS14480	COG0840	transmembrane signaling receptor activity
HI801_RS14500	COG1773	rubredoxin
HI801_RS14505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HI801_RS14510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI801_RS14515	COG1704	LemA family
HI801_RS14560	COG4964	Belongs to the GSP D family
HI801_RS14645	COG4269	membrane
HI801_RS14650	COG0459	protein refolding
HI801_RS14655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HI801_RS14680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HI801_RS14685	COG0583	DNA-binding transcription factor activity
HI801_RS14690	COG0596	Alpha beta hydrolase
HI801_RS14695	COG1073	alpha beta
HI801_RS14740	COG2207	Transcriptional regulator
HI801_RS14750	COG2963	transposase activity
HI801_RS14765	COG0513	Belongs to the DEAD box helicase family
HI801_RS14780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HI801_RS14785	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HI801_RS14790	COG2974	May be involved in recombination
HI801_RS14815	COG0697	spore germination
HI801_RS14855	COG0840	transmembrane signaling receptor activity
HI801_RS14860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HI801_RS14880	COG2995	paraquat-inducible protein a
HI801_RS14885	COG3008	intermembrane lipid transfer
HI801_RS14885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HI801_RS14970	COG0738	Major facilitator superfamily
HI801_RS14975	COG2027	D-alanyl-D-alanine carboxypeptidase
HI801_RS14980	COG1763	Mo-molybdopterin cofactor biosynthetic process
HI801_RS14990	COG0546	phosphoglycolate phosphatase activity
HI801_RS15000	COG0009	L-threonylcarbamoyladenylate synthase
HI801_RS15005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HI801_RS15010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HI801_RS15015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HI801_RS15025	COG0469	pyruvate kinase activity
HI801_RS15030	COG0126	phosphoglycerate kinase activity
HI801_RS15060	COG0859	PFAM glycosyl transferase family 9
HI801_RS15070	COG0429	hydrolase of the alpha beta-hydrolase fold
HI801_RS15080	COG4783	chaperone-mediated protein folding
HI801_RS15085	COG0315	cyclic pyranopterin monophosphate synthase activity
HI801_RS15090	COG3307	-O-antigen
HI801_RS15095	COG4969	Belongs to the N-Me-Phe pilin family
HI801_RS15100	COG4969	Belongs to the N-Me-Phe pilin family
HI801_RS15105	COG0861	Integral membrane protein TerC family
HI801_RS15110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HI801_RS15115	COG0045	succinate-CoA ligase (ADP-forming) activity
HI801_RS15125	COG2137	regulation of response to DNA damage stimulus
HI801_RS15130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HI801_RS15140	COG0642	Histidine kinase
HI801_RS15150	COG0477	Major facilitator Superfamily
HI801_RS15195	COG0513	Belongs to the DEAD box helicase family
HI801_RS15225	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS15250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HI801_RS15255	COG1702	phosphate starvation-inducible protein PhoH
HI801_RS15260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HI801_RS15265	COG4535	Mg2 and Co2 transporter CorC
HI801_RS15270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HI801_RS15275	COG0752	glycyl-tRNA synthetase alpha subunit
HI801_RS15285	COG0751	glycine-tRNA ligase activity
HI801_RS15290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HI801_RS15295	COG0204	Acyl-transferase
HI801_RS15305	COG0346	lactoylglutathione lyase activity
HI801_RS15310	COG0697	spore germination
HI801_RS15315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HI801_RS15320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HI801_RS15325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS15330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HI801_RS15350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HI801_RS15360	COG0006	proline dipeptidase activity
HI801_RS15365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI801_RS15375	COG4680	protein conserved in bacteria
HI801_RS15390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HI801_RS15395	COG0138	bifunctional purine biosynthesis protein purh
HI801_RS15400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HI801_RS15410	COG0632	four-way junction helicase activity
HI801_RS15415	COG2255	four-way junction helicase activity
HI801_RS15430	COG1490	D-aminoacyl-tRNA deacylase activity
HI801_RS15435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HI801_RS15440	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HI801_RS15445	COG0316	Belongs to the HesB IscA family
HI801_RS15460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HI801_RS15465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HI801_RS15485	COG0418	dihydroorotase activity
HI801_RS15495	COG0473	3-isopropylmalate dehydrogenase activity
HI801_RS15500	COG0121	glutamine amidotransferase
HI801_RS15505	COG1126	abc transporter atp-binding protein
HI801_RS15510	COG0765	amino acid transport
HI801_RS15515	COG0765	amino acid transport
HI801_RS15525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HI801_RS15535	COG5265	(ABC) transporter
HI801_RS15545	COG1024	Enoyl-CoA hydratase
HI801_RS15550	COG0183	Belongs to the thiolase family
HI801_RS15555	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI801_RS15555	COG1024	Enoyl-CoA hydratase
HI801_RS15560	COG1960	acyl-CoA dehydrogenase activity
HI801_RS15575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HI801_RS15580	COG3568	Endonuclease Exonuclease Phosphatase
HI801_RS15585	COG0494	nUDIX hydrolase
HI801_RS15595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HI801_RS15620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HI801_RS15635	COG2226	methyltransferase
HI801_RS15645	COG4178	(ABC) transporter
HI801_RS15660	COG1238	metal cluster binding
HI801_RS15665	COG0700	Nucleoside recognition
HI801_RS15680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HI801_RS15685	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HI801_RS15685	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HI801_RS15715	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS15720	COG3265	gluconokinase activity
HI801_RS15735	COG2391	methyltransferase activity
HI801_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS15765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HI801_RS15790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI801_RS15825	COG0629	single-stranded DNA binding
HI801_RS15830	COG2814	Major facilitator Superfamily
HI801_RS15845	COG1280	lysine exporter protein (LysE YggA)
HI801_RS15850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HI801_RS15855	COG0693	protein deglycase activity
HI801_RS15875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HI801_RS15890	COG1137	ATPase activity
HI801_RS15895	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HI801_RS15900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HI801_RS15910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HI801_RS15920	COG1660	Displays ATPase and GTPase activities
HI801_RS15930	COG1194	a g-specific adenine glycosylase
HI801_RS15940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HI801_RS15950	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HI801_RS15955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HI801_RS15965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HI801_RS15970	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HI801_RS15975	COG0193	aminoacyl-tRNA hydrolase activity
HI801_RS15985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HI801_RS15990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HI801_RS15995	COG0742	ribosomal rna small subunit methyltransferase
HI801_RS16000	COG0612	Peptidase, M16
HI801_RS16005	COG0612	Peptidase, M16
HI801_RS16020	COG0625	glutathione transferase activity
HI801_RS16030	COG3707	response regulator
HI801_RS16035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI801_RS16040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI801_RS16045	COG1116	anion transmembrane transporter activity
HI801_RS16050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI801_RS16055	COG1741	Belongs to the pirin family
HI801_RS16065	COG5001	Diguanylate cyclase
HI801_RS16065	COG3300	MHYT domain
HI801_RS16070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HI801_RS16075	COG1999	signal sequence binding
HI801_RS16080	COG0109	protoheme IX farnesyltransferase activity
HI801_RS16085	COG1612	heme a metabolic process
HI801_RS16115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HI801_RS16120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI801_RS16135	COG2226	methyltransferase
HI801_RS16140	COG1040	competence protein
HI801_RS16150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HI801_RS16155	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HI801_RS16160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HI801_RS16165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HI801_RS16170	COG0588	phosphoglycerate mutase activity
HI801_RS16175	COG0793	Belongs to the peptidase S41A family
HI801_RS16195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HI801_RS16200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HI801_RS16210	COG0189	ligase activity
HI801_RS16220	COG0004	ammonium transporteR
HI801_RS16245	COG0606	chelatase, subunit chli
HI801_RS16265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HI801_RS16275	COG2204	response regulator
HI801_RS16280	COG4191	Histidine kinase
HI801_RS16285	COG1301	dicarboxylic acid transport
HI801_RS16290	COG3411	Ferredoxin
HI801_RS16300	COG1686	Belongs to the peptidase S11 family
HI801_RS16305	COG2921	Belongs to the UPF0250 family
HI801_RS16310	COG0583	DNA-binding transcription factor activity
HI801_RS16320	COG0321	lipoyl(octanoyl) transferase activity
HI801_RS16325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HI801_RS16340	COG3511	phospholipase C
HI801_RS16370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HI801_RS16375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HI801_RS16375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HI801_RS16380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HI801_RS16390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HI801_RS16415	COG1024	Enoyl-CoA hydratase
HI801_RS16445	COG2267	carboxylic ester hydrolase activity
HI801_RS16465	COG1410	methionine synthase
HI801_RS16465	COG0646	methionine synthase
HI801_RS16475	COG2197	response regulator
HI801_RS16505	COG0018	arginyl-trna synthetase
HI801_RS16515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HI801_RS16520	COG4221	oxidoreductase activity
HI801_RS16530	COG2329	Antibiotic biosynthesis monooxygenase
HI801_RS16540	COG0789	Transcriptional regulator
HI801_RS16545	COG1960	acyl-CoA dehydrogenase activity
HI801_RS16550	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HI801_RS16555	COG0288	reversible hydration of carbon dioxide
HI801_RS16560	COG0183	Belongs to the thiolase family
HI801_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS16570	COG1960	acyl-CoA dehydrogenase activity
HI801_RS16585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HI801_RS16590	COG3012	SEC-C Motif Domain Protein
HI801_RS16595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HI801_RS16605	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HI801_RS16610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HI801_RS16615	COG4770	biotin carboxylase activity
HI801_RS16630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HI801_RS16650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI801_RS16660	COG0596	Alpha beta hydrolase
HI801_RS16680	COG3039	Transposase
HI801_RS16695	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI801_RS16700	COG0583	DNA-binding transcription factor activity
HI801_RS16730	COG1703	isobutyryl-CoA mutase activity
HI801_RS16730	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HI801_RS16730	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HI801_RS16775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI801_RS16790	COG0430	RNA-3'-phosphate cyclase activity
HI801_RS16795	COG3541	Predicted nucleotidyltransferase
HI801_RS16800	COG1690	Belongs to the RtcB family
HI801_RS16810	COG4650	regulator
HI801_RS16825	COG1254	Belongs to the acylphosphatase family
HI801_RS16840	COG0667	Aldo Keto reductase
HI801_RS16845	COG2814	Major facilitator Superfamily
HI801_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS16855	COG0583	DNA-binding transcription factor activity
HI801_RS16860	COG0519	Catalyzes the synthesis of GMP from XMP
HI801_RS16860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HI801_RS16875	COG1733	regulation of RNA biosynthetic process
HI801_RS16915	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HI801_RS16935	COG4372	Transposase
HI801_RS16940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HI801_RS16945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HI801_RS16950	COG0071	Belongs to the small heat shock protein (HSP20) family
HI801_RS16960	COG3038	cytochrome b561
HI801_RS16980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HI801_RS16985	COG1063	alcohol dehydrogenase
HI801_RS16995	COG2197	response regulator
HI801_RS17000	COG3851	Histidine kinase
HI801_RS17005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HI801_RS17035	COG0589	response to stress
HI801_RS17040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HI801_RS17060	COG0589	response to stress
HI801_RS17070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HI801_RS17075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HI801_RS17085	COG0037	tRNA processing
HI801_RS17090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI801_RS17095	COG0546	phosphoglycolate phosphatase activity
HI801_RS17095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HI801_RS17120	COG0493	'glutamate synthase
HI801_RS17135	COG0842	Transport permease protein
HI801_RS17140	COG1131	(ABC) transporter
HI801_RS17155	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS17160	COG0583	DNA-binding transcription factor activity
HI801_RS17165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HI801_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS17190	COG2223	nitrite transmembrane transporter activity
HI801_RS17205	COG0697	spore germination
HI801_RS17230	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HI801_RS17250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HI801_RS17255	COG4682	membrane
HI801_RS17260	COG0708	Exodeoxyribonuclease III
HI801_RS17265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HI801_RS17270	COG2326	polyphosphate kinase activity
HI801_RS17275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HI801_RS17280	COG1560	Kdo2-lipid A biosynthetic process
HI801_RS17290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HI801_RS17310	COG0517	IMP dehydrogenase activity
HI801_RS17320	COG1522	sequence-specific DNA binding
HI801_RS17365	COG1960	acyl-CoA dehydrogenase activity
HI801_RS17400	COG2070	2-Nitropropane dioxygenase
HI801_RS17405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HI801_RS17420	COG2022	thiamine diphosphate biosynthetic process
HI801_RS17430	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HI801_RS17460	COG0351	phosphomethylpyrimidine kinase
HI801_RS17470	COG1785	Belongs to the alkaline phosphatase family
HI801_RS17475	COG1785	Belongs to the alkaline phosphatase family
HI801_RS17490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HI801_RS17495	COG1950	PFAM Membrane protein of
HI801_RS17500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HI801_RS17510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HI801_RS17530	COG0617	tRNA 3'-terminal CCA addition
HI801_RS17540	COG3246	L-lysine catabolic process to acetate
HI801_RS17545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HI801_RS17570	COG2204	response regulator
HI801_RS17575	COG5000	phosphorelay sensor kinase activity
HI801_RS17590	COG0501	Belongs to the peptidase M48B family
HI801_RS17600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HI801_RS17610	COG0242	peptide deformylase activity
HI801_RS17615	COG1652	LysM domain
HI801_RS17620	COG0758	DNA mediated transformation
HI801_RS17635	COG0583	DNA-binding transcription factor activity
HI801_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS17645	COG0772	Belongs to the SEDS family
HI801_RS17650	COG0768	penicillin binding
HI801_RS17660	COG1792	Involved in formation and maintenance of cell shape
HI801_RS17665	COG1077	Cell shape determining protein MreB Mrl
HI801_RS17670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HI801_RS17675	COG0154	amidase activity
HI801_RS17690	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HI801_RS17700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HI801_RS17705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HI801_RS17725	COG0523	cobalamin synthesis protein
HI801_RS17740	COG0747	negative chemotaxis
HI801_RS17745	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HI801_RS17750	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HI801_RS17760	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HI801_RS17790	COG1595	DNA-templated transcription, initiation
HI801_RS17795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HI801_RS17810	COG3385	transposase activity
HI801_RS17820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HI801_RS17830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HI801_RS17840	COG3385	transposase activity
HI801_RS17855	COG2879	small protein
HI801_RS17860	COG1966	Carbon starvation protein
HI801_RS17875	COG3622	Belongs to the hyi family
HI801_RS17885	COG0745	RESPONSE REGULATOR receiver
HI801_RS17890	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HI801_RS17895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HI801_RS17900	COG3384	dioxygenase
HI801_RS17915	COG1309	transcriptional regulator
HI801_RS17920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS17925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI801_RS17935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HI801_RS17950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HI801_RS17955	COG0706	membrane insertase activity
HI801_RS17960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HI801_RS17965	COG0594	ribonuclease P activity
HI801_RS17970	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HI801_RS17980	COG1278	Cold shock
HI801_RS18005	COG0477	Major facilitator Superfamily
HI801_RS18010	COG4191	Histidine kinase
HI801_RS18020	COG4377	Putative membrane peptidase family (DUF2324)
HI801_RS18030	COG3447	MASE1 domain protein
HI801_RS18030	COG5001	Diguanylate cyclase
HI801_RS18030	COG5002	protein histidine kinase activity
HI801_RS18070	COG0038	chloride channel
HI801_RS18085	COG1881	PFAM PEBP family protein
HI801_RS18110	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI801_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS18140	COG1024	Enoyl-CoA hydratase
HI801_RS18145	COG1960	acyl-CoA dehydrogenase activity
HI801_RS18210	COG0477	Major facilitator Superfamily
HI801_RS18215	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HI801_RS18225	COG2814	Major facilitator Superfamily
HI801_RS18260	COG0725	ABC transporter, periplasmic molybdate-binding protein
HI801_RS18275	COG0714	Associated with various cellular activities
HI801_RS18290	COG0288	reversible hydration of carbon dioxide
HI801_RS18340	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HI801_RS18350	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HI801_RS18355	COG2944	sequence-specific DNA binding
HI801_RS18405	COG3039	Transposase
HI801_RS18450	COG3210	domain, Protein
HI801_RS18465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS18485	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
HI801_RS18505	COG0705	Rhomboid family
HI801_RS18560	COG0583	DNA-binding transcription factor activity
HI801_RS18595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI801_RS18600	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HI801_RS18605	COG2188	Transcriptional regulator
HI801_RS18610	COG3256	nitric oxide reductase
HI801_RS18655	COG4651	solute:proton antiporter activity
HI801_RS18655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HI801_RS18675	COG2192	nodulation
HI801_RS18760	COG0667	Aldo Keto reductase
HI801_RS18815	COG0577	efflux transmembrane transporter activity
HI801_RS18815	COG1136	(ABC) transporter
HI801_RS18820	COG1136	(ABC) transporter
HI801_RS18845	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HI801_RS18855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS18865	COG0745	RESPONSE REGULATOR receiver
HI801_RS18870	COG2205	protein histidine kinase activity
HI801_RS18880	COG0583	DNA-binding transcription factor activity
HI801_RS18890	COG0469	pyruvate kinase activity
HI801_RS18900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI801_RS18925	COG2205	protein histidine kinase activity
HI801_RS18930	COG1045	serine acetyltransferase
HI801_RS18935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI801_RS18935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI801_RS18955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS18970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HI801_RS18970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS19000	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HI801_RS19005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HI801_RS19010	COG0644	oxidoreductase
HI801_RS19020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI801_RS19025	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS19025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS19025	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS19025	COG0300	oxidoreductase activity
HI801_RS19025	COG3321	synthase
HI801_RS19030	COG2267	carboxylic ester hydrolase activity
HI801_RS19035	COG0477	Major facilitator Superfamily
HI801_RS19070	COG1360	Flagellar Motor Protein
HI801_RS19075	COG0745	RESPONSE REGULATOR receiver
HI801_RS19085	COG0835	chemotaxis
HI801_RS19090	COG0840	transmembrane signaling receptor activity
HI801_RS19100	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HI801_RS19105	COG2201	protein-glutamate methylesterase activity
HI801_RS19110	COG0745	RESPONSE REGULATOR receiver
HI801_RS19115	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HI801_RS19125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS19130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HI801_RS19135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HI801_RS19140	COG2271	Major facilitator Superfamily
HI801_RS19145	COG1309	transcriptional regulator
HI801_RS19155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HI801_RS19170	COG1191	sigma factor activity
HI801_RS19195	COG0762	integral membrane protein
HI801_RS19205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI801_RS19215	COG2824	Alkylphosphonate utilization operon protein PhnA
HI801_RS19255	COG3039	Transposase
HI801_RS19285	COG3039	Transposase
HI801_RS19315	COG4263	nitrous-oxide reductase activity
HI801_RS19330	COG0204	Acyl-transferase
HI801_RS19335	COG0567	Dehydrogenase, E1 component
HI801_RS19340	COG0840	transmembrane signaling receptor activity
HI801_RS19350	COG2814	Major facilitator Superfamily
HI801_RS19360	COG0583	DNA-binding transcription factor activity
HI801_RS19380	COG0251	oxidation-reduction process
HI801_RS19390	COG0640	Transcriptional regulator
HI801_RS19430	COG4372	Transposase
HI801_RS19455	COG0582	viral genome integration into host DNA
HI801_RS19460	COG1522	sequence-specific DNA binding
HI801_RS19470	COG0251	oxidation-reduction process
HI801_RS19530	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HI801_RS19555	COG0683	leucine binding
HI801_RS19595	COG3766	membrane
HI801_RS19615	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HI801_RS19645	COG4968	Prepilin-type N-terminal cleavage methylation domain
HI801_RS19650	COG1609	Transcriptional regulator
HI801_RS19660	COG1621	beta-fructofuranosidase activity
HI801_RS19685	COG0114	fumarate hydratase activity
HI801_RS19690	COG0477	Major facilitator Superfamily
HI801_RS19710	COG1742	UPF0060 membrane protein
HI801_RS19715	COG0668	transmembrane transport
HI801_RS19745	COG0730	response to heat
HI801_RS19750	COG0583	DNA-binding transcription factor activity
HI801_RS19760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI801_RS19765	COG0730	response to heat
HI801_RS19770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HI801_RS19795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HI801_RS19815	COG3550	peptidyl-serine autophosphorylation
HI801_RS19850	COG0251	oxidation-reduction process
HI801_RS19860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI801_RS19865	COG1294	oxidase, subunit
HI801_RS19870	COG1271	oxidase subunit
HI801_RS19880	COG2951	lytic endotransglycosylase activity
HI801_RS19915	COG0473	3-isopropylmalate dehydrogenase activity
HI801_RS19915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI801_RS19920	COG0436	Aminotransferase
HI801_RS19925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI801_RS19955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HI801_RS19960	COG0840	transmembrane signaling receptor activity
HI801_RS19965	COG2223	nitrite transmembrane transporter activity
HI801_RS19970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI801_RS19980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI801_RS19985	COG0243	molybdopterin cofactor binding
HI801_RS20000	COG0534	Mate efflux family protein
HI801_RS20010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HI801_RS20020	COG0840	transmembrane signaling receptor activity
HI801_RS20025	COG5001	Diguanylate cyclase
HI801_RS20025	COG3300	MHYT domain
HI801_RS20030	COG1271	oxidase subunit
HI801_RS20035	COG1294	oxidase, subunit
HI801_RS20085	COG0745	RESPONSE REGULATOR receiver
HI801_RS20105	COG2197	response regulator
HI801_RS20110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HI801_RS20115	COG0800	Aldolase
HI801_RS20130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HI801_RS20155	COG2274	protein secretion by the type I secretion system
HI801_RS20170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI801_RS20170	COG2205	protein histidine kinase activity
HI801_RS20195	COG1858	cytochrome C peroxidase
HI801_RS20200	COG1253	flavin adenine dinucleotide binding
HI801_RS20220	COG1858	cytochrome C peroxidase
HI801_RS20250	COG2205	protein histidine kinase activity
HI801_RS20255	COG0745	RESPONSE REGULATOR receiver
HI801_RS20270	COG3813	Protein conserved in bacteria
HI801_RS20290	COG3300	MHYT domain
HI801_RS20290	COG5001	Diguanylate cyclase
HI801_RS20305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HI801_RS20310	COG4149	molybdate abc transporter
HI801_RS20315	COG2066	Belongs to the glutaminase family
HI801_RS20325	COG2197	response regulator
HI801_RS20335	COG3501	Rhs element vgr protein
HI801_RS20345	COG3209	COG3209 Rhs family protein
HI801_RS20345	COG4104	PAAR repeat-containing protein
HI801_RS20380	COG0640	Transcriptional regulator
HI801_RS20385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HI801_RS20390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HI801_RS20405	COG1064	alcohol dehydrogenase
HI801_RS20430	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HI801_RS20455	COG1064	alcohol dehydrogenase
HI801_RS20465	COG0583	DNA-binding transcription factor activity
HI801_RS20475	COG3321	synthase
HI801_RS20475	COG0604	alcohol dehydrogenase
HI801_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS20485	COG2030	dehydratase
HI801_RS20535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS20545	COG0583	DNA-binding transcription factor activity
HI801_RS20560	COG1764	response to oxidative stress
HI801_RS20565	COG1846	Transcriptional regulator
HI801_RS20570	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HI801_RS20575	COG1877	trehalose-phosphatase activity
HI801_RS20590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HI801_RS20615	COG2197	response regulator
HI801_RS20630	COG3039	Transposase
HI801_RS20665	COG4964	Belongs to the GSP D family
HI801_RS20720	COG0673	inositol 2-dehydrogenase activity
HI801_RS20725	COG2831	hemolysin activation secretion protein
HI801_RS20825	COG0673	inositol 2-dehydrogenase activity
HI801_RS20835	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS20840	COG4689	acetoacetate decarboxylase
HI801_RS20865	COG1278	Cold shock
HI801_RS20870	COG3158	transport of potassium into the cell
HI801_RS20875	COG5001	Diguanylate cyclase
HI801_RS20875	COG3300	MHYT domain
HI801_RS20880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HI801_RS20890	COG0243	molybdopterin cofactor binding
HI801_RS20895	COG2223	nitrite transmembrane transporter activity
HI801_RS20920	COG0745	RESPONSE REGULATOR receiver
HI801_RS20955	COG3220	belongs to the UPF0276 family
HI801_RS21035	COG1596	polysaccharide export
HI801_RS21040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HI801_RS21045	COG0489	protein tyrosine kinase activity
HI801_RS21045	COG3206	protein involved in exopolysaccharide biosynthesis
HI801_RS21050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HI801_RS21055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HI801_RS21060	COG2244	polysaccharide biosynthetic process
HI801_RS21075	COG0110	maltose O-acetyltransferase activity
HI801_RS21095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HI801_RS21105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HI801_RS21150	COG0583	DNA-binding transcription factor activity
HI801_RS21160	COG1301	dicarboxylic acid transport
HI801_RS21165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HI801_RS21185	COG1999	signal sequence binding
HI801_RS21200	COG1454	alcohol dehydrogenase
HI801_RS21205	COG0477	Major facilitator Superfamily
HI801_RS21210	COG0352	thiamine-phosphate diphosphorylase activity
HI801_RS21230	COG2197	response regulator
HI801_RS21235	COG3850	Histidine kinase
HI801_RS21240	COG1763	Mo-molybdopterin cofactor biosynthetic process
HI801_RS21245	COG2181	nitrate reductase activity
HI801_RS21250	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HI801_RS21255	COG1140	nitrate reductase beta subunit
HI801_RS21260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HI801_RS21265	COG2223	nitrite transmembrane transporter activity
HI801_RS21280	COG0826	peptidase U32
HI801_RS21285	COG0826	peptidase U32
HI801_RS21290	COG3154	lipid carrier protein
HI801_RS21320	COG1396	sequence-specific DNA binding
HI801_RS21330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI801_RS21335	COG3604	Transcriptional regulator
HI801_RS21340	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HI801_RS21380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS21400	COG1063	alcohol dehydrogenase
HI801_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS21410	COG3265	gluconokinase activity
HI801_RS21420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI801_RS21425	COG0436	Aminotransferase
HI801_RS21435	COG0511	ligase activity, forming carbon-carbon bonds
HI801_RS21445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HI801_RS21450	COG1984	allophanate hydrolase subunit 2
HI801_RS21460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HI801_RS21465	COG4221	oxidoreductase activity
HI801_RS21470	COG0765	amino acid transport
HI801_RS21475	COG0765	amino acid transport
HI801_RS21480	COG1126	abc transporter atp-binding protein
HI801_RS21485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI801_RS21505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS21535	COG0415	Belongs to the DNA photolyase family
HI801_RS21545	COG0459	protein refolding
HI801_RS21595	COG0071	Belongs to the small heat shock protein (HSP20) family
HI801_RS21615	COG2801	Transposase and inactivated derivatives
HI801_RS21640	COG1309	transcriptional regulator
HI801_RS21655	COG0583	DNA-binding transcription factor activity
HI801_RS21665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI801_RS21690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HI801_RS21720	COG1674	ftsk spoiiie
HI801_RS21740	COG5434	Belongs to the glycosyl hydrolase 28 family
HI801_RS21765	COG4886	Leucine-rich repeat (LRR) protein
HI801_RS21770	COG1450	Type ii and iii secretion system protein
HI801_RS21775	COG2207	Transcriptional regulator
HI801_RS21820	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HI801_RS21825	COG4789	Type iii secretion
HI801_RS21840	COG4790	Type iii secretion
HI801_RS21880	COG0745	RESPONSE REGULATOR receiver
HI801_RS21885	COG2197	response regulator
HI801_RS21895	COG1595	DNA-templated transcription, initiation
HI801_RS21940	COG0840	transmembrane signaling receptor activity
HI801_RS21965	COG1056	cytidyltransferase-related domain
HI801_RS21965	COG1051	belongs to the nudix hydrolase family
HI801_RS21970	COG2271	Major facilitator Superfamily
HI801_RS21985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI801_RS21990	COG2721	sulfolactate sulfo-lyase activity
HI801_RS22000	COG2271	Major facilitator Superfamily
HI801_RS22010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI801_RS22015	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HI801_RS22025	COG0583	DNA-binding transcription factor activity
HI801_RS22035	COG0697	spore germination
HI801_RS22050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI801_RS22075	COG0672	)-iron permease
HI801_RS22080	COG0789	Transcriptional regulator
HI801_RS22110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS22125	COG0789	Transcriptional regulator
HI801_RS22145	COG2020	methyltransferase activity
HI801_RS22155	COG4232	protein-disulfide reductase activity
HI801_RS22175	COG5002	protein histidine kinase activity
HI801_RS22180	COG0745	RESPONSE REGULATOR receiver
HI801_RS22185	COG2132	Multicopper oxidase
HI801_RS22245	COG0579	oxidoreductase
HI801_RS22260	COG4206	TonB-dependent receptor
HI801_RS22265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HI801_RS22280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HI801_RS22295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HI801_RS22305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HI801_RS22310	COG3620	sequence-specific DNA binding
HI801_RS22315	COG0587	DNA-directed DNA polymerase activity
HI801_RS22330	COG2814	Major facilitator Superfamily
HI801_RS22345	COG0436	Aminotransferase
HI801_RS22360	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS22360	COG0300	oxidoreductase activity
HI801_RS22360	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS22360	COG3321	synthase
HI801_RS22360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS22375	COG2192	nodulation
HI801_RS22380	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS22405	COG0525	valine-tRNA ligase activity
HI801_RS22420	COG3916	Acyl-homoserine-lactone synthase
HI801_RS22425	COG2197	response regulator
HI801_RS22430	COG3039	Transposase
HI801_RS22560	COG3501	Rhs element vgr protein
HI801_RS22620	COG3501	Rhs element vgr protein
HI801_RS22650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HI801_RS22670	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HI801_RS22690	COG1730	sister chromatid segregation
HI801_RS22695	COG1858	cytochrome C peroxidase
HI801_RS22780	COG1690	Belongs to the RtcB family
HI801_RS22785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HI801_RS22810	COG3483	tryptophan 2,3-dioxygenase activity
HI801_RS22825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HI801_RS22845	COG1960	acyl-CoA dehydrogenase activity
HI801_RS22885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI801_RS22890	COG0134	indole-3-glycerol-phosphate synthase activity
HI801_RS22895	COG0019	diaminopimelate decarboxylase activity
HI801_RS22900	COG0259	pyridoxamine-phosphate oxidase activity
HI801_RS22905	COG0583	DNA-binding transcription factor activity
HI801_RS22910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HI801_RS22935	COG1024	Enoyl-CoA hydratase
HI801_RS22960	COG2807	transmembrane transport
HI801_RS22965	COG2818	Glycosylase
HI801_RS22980	COG2814	Major facilitator Superfamily
HI801_RS22990	COG1335	isochorismatase
HI801_RS23005	COG1846	Transcriptional regulator
HI801_RS23015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS23035	COG2132	Multicopper oxidase
HI801_RS23040	COG0745	RESPONSE REGULATOR receiver
HI801_RS23045	COG5002	protein histidine kinase activity
HI801_RS23060	COG1960	acyl-CoA dehydrogenase activity
HI801_RS23065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI801_RS23080	COG1024	Enoyl-CoA hydratase
HI801_RS23085	COG1024	Enoyl-CoA hydratase
HI801_RS23090	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HI801_RS23095	COG1522	sequence-specific DNA binding
HI801_RS23115	COG3039	Transposase
HI801_RS23125	COG3251	PFAM MbtH domain protein
HI801_RS23130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HI801_RS23145	COG4941	Belongs to the sigma-70 factor family
HI801_RS23150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HI801_RS23175	COG0438	transferase activity, transferring glycosyl groups
HI801_RS23220	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HI801_RS23225	COG3411	Ferredoxin
HI801_RS23240	COG1648	precorrin-2 dehydrogenase activity
HI801_RS23240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HI801_RS23250	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HI801_RS23285	COG1797	cobyrinic acid a,c-diamide synthase activity
HI801_RS23290	COG0778	Nitroreductase
HI801_RS23345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HI801_RS23350	COG2151	metal-sulfur cluster biosynthetic enzyme
HI801_RS23355	COG3396	Phenylacetate-CoA oxygenase
HI801_RS23360	COG3460	Phenylacetate-CoA oxygenase
HI801_RS23365	COG3396	Phenylacetate-CoA oxygenase
HI801_RS23370	COG1404	Belongs to the peptidase S8 family
HI801_RS23395	COG0784	Response regulator, receiver
HI801_RS23395	COG0835	chemotaxis
HI801_RS23405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI801_RS23450	COG5297	Belongs to the glycosyl hydrolase family 6
HI801_RS23455	COG4372	Transposase
HI801_RS23540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI801_RS23550	COG4372	Transposase
HI801_RS23625	COG3501	Rhs element vgr protein
HI801_RS23650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI801_RS23725	COG1113	amino acid transport
HI801_RS23750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI801_RS23760	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
HI801_RS23760	COG3064	Membrane
HI801_RS23760	COG3210	domain, Protein
HI801_RS23795	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HI801_RS24005	COG0402	S-adenosylhomocysteine deaminase activity
HI801_RS24060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI801_RS24105	COG2910	NAD(P)H-binding
HI801_RS24125	COG0443	Heat shock 70 kDa protein
HI801_RS24130	COG1914	H( )-stimulated, divalent metal cation uptake system
HI801_RS24135	COG3706	GGDEF domain
HI801_RS24145	COG3501	Rhs element vgr protein
HI801_RS24175	COG0668	transmembrane transport
HI801_RS24195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HI801_RS24210	COG0840	transmembrane signaling receptor activity
HI801_RS24220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI801_RS24260	COG0537	adenosine 5'-monophosphoramidase activity
HI801_RS24295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI801_RS24315	COG2423	ornithine cyclodeaminase activity
HI801_RS24320	COG1522	sequence-specific DNA binding
HI801_RS24325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI801_RS24335	COG1126	abc transporter atp-binding protein
HI801_RS24340	COG0583	DNA-binding transcription factor activity
HI801_RS24350	COG1902	pentaerythritol trinitrate reductase activity
HI801_RS24400	COG0583	DNA-binding transcription factor activity
HI801_RS24425	COG2814	Major facilitator Superfamily
HI801_RS24430	COG1126	abc transporter atp-binding protein
HI801_RS24450	COG0019	diaminopimelate decarboxylase activity
HI801_RS24460	COG4264	IucA IucC family
HI801_RS24465	COG4264	IucA IucC family
HI801_RS24470	COG2814	Major facilitator Superfamily
HI801_RS24475	COG4264	IucA IucC family
HI801_RS24480	COG2423	ornithine cyclodeaminase activity
HI801_RS24485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HI801_RS24500	COG4774	siderophore transport
HI801_RS24510	COG2223	nitrite transmembrane transporter activity
HI801_RS24555	COG0318	PFAM AMP-dependent synthetase and ligase
HI801_RS24605	COG2203	Gaf domain
HI801_RS24605	COG3706	GGDEF domain
HI801_RS24605	COG4251	negative regulation of phosphorylation
HI801_RS24605	COG5001	Diguanylate cyclase
HI801_RS24615	COG4251	negative regulation of phosphorylation
HI801_RS24615	COG3706	GGDEF domain
HI801_RS24615	COG2203	Gaf domain
HI801_RS24615	COG5001	Diguanylate cyclase
HI801_RS24650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HI801_RS24660	COG1677	Flagellar hook-basal body complex protein FliE
HI801_RS24675	COG1846	Transcriptional regulator
HI801_RS24700	COG2197	response regulator
HI801_RS24730	COG1338	Plays a role in the flagellum-specific transport system
HI801_RS24735	COG1987	bacterial-type flagellum assembly
HI801_RS24750	COG0204	Acyl-transferase
HI801_RS24760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI801_RS24770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI801_RS24780	COG2986	histidine ammonia-lyase
HI801_RS24800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI801_RS24810	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS24815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI801_RS24830	COG2226	methyltransferase
HI801_RS24850	COG1256	bacterial-type flagellum assembly
HI801_RS24860	COG1706	bacterial-type flagellum-dependent cell motility
HI801_RS24865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HI801_RS24875	COG4787	bacterial-type flagellum-dependent cell motility
HI801_RS24880	COG1749	Flagellar hook protein flgE
HI801_RS24885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HI801_RS24895	COG1815	bacterial-type flagellum-dependent cell motility
HI801_RS24915	COG2197	response regulator
HI801_RS24920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI801_RS24925	COG2188	Transcriptional regulator
HI801_RS24930	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI801_RS24960	COG0473	3-isopropylmalate dehydrogenase activity
HI801_RS24975	COG1764	response to oxidative stress
HI801_RS24995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HI801_RS25005	COG0789	Transcriptional regulator
HI801_RS25030	COG0589	response to stress
HI801_RS25045	COG2205	protein histidine kinase activity
HI801_RS25050	COG0745	RESPONSE REGULATOR receiver
HI801_RS25055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS25060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI801_RS25075	COG1695	Transcriptional regulator
HI801_RS25080	COG0583	DNA-binding transcription factor activity
HI801_RS25085	COG2070	2-Nitropropane dioxygenase
HI801_RS25095	COG1028	Short-chain dehydrogenase reductase Sdr
HI801_RS25105	COG0840	transmembrane signaling receptor activity
HI801_RS25140	COG2274	protein secretion by the type I secretion system
HI801_RS25145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS25160	COG1215	transferase activity, transferring glycosyl groups
HI801_RS25165	COG0726	polysaccharide deacetylase
HI801_RS25165	COG1649	PFAM Uncharacterised BCR, COG1649
HI801_RS25175	COG2197	response regulator
HI801_RS25185	COG0534	Mate efflux family protein
HI801_RS25190	COG0531	amino acid
HI801_RS25195	COG3706	GGDEF domain
HI801_RS25210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HI801_RS25275	COG0456	acetyltransferase
HI801_RS25275	COG0454	-acetyltransferase
HI801_RS25285	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI801_RS25300	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HI801_RS25320	COG0840	transmembrane signaling receptor activity
HI801_RS25330	COG3447	MASE1 domain protein
HI801_RS25330	COG5001	Diguanylate cyclase
HI801_RS25330	COG5002	protein histidine kinase activity
HI801_RS25340	COG1918	ferrous iron import across plasma membrane
HI801_RS25340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HI801_RS25360	COG0735	belongs to the Fur family
HI801_RS25365	COG3634	alkyl hydroperoxide reductase activity
HI801_RS25375	COG4771	TonB-dependent receptor
HI801_RS25380	COG3720	iron ion transport
HI801_RS25385	COG0297	glycogen (starch) synthase activity
HI801_RS25390	COG0366	Alpha amylase catalytic
HI801_RS25395	COG0366	Alpha amylase catalytic
HI801_RS25400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HI801_RS25410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HI801_RS25415	COG1640	4-alpha-glucanotransferase
HI801_RS25425	COG2814	Major facilitator Superfamily
HI801_RS25465	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS25470	COG1024	Enoyl-CoA hydratase
HI801_RS25475	COG1846	Transcriptional regulator
HI801_RS25510	COG3039	Transposase
HI801_RS25550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HI801_RS25590	COG1607	acyl-coa hydrolase
HI801_RS25605	COG0028	Belongs to the TPP enzyme family
HI801_RS25615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HI801_RS25655	COG0730	response to heat
HI801_RS25680	COG2706	6-phosphogluconolactonase activity
HI801_RS25735	COG1104	cysteine desulfurase activity
HI801_RS25770	COG0529	Catalyzes the synthesis of activated sulfate
HI801_RS25780	COG3251	PFAM MbtH domain protein
HI801_RS25785	COG0534	Mate efflux family protein
HI801_RS25795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HI801_RS25820	COG3039	Transposase
HI801_RS25840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HI801_RS25865	COG4796	Type ii and iii secretion system protein
HI801_RS25875	COG4968	Prepilin-type N-terminal cleavage methylation domain
HI801_RS25895	COG4677	pectinesterase activity
HI801_RS25905	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI801_RS25905	COG1902	pentaerythritol trinitrate reductase activity
HI801_RS25920	COG0697	spore germination
HI801_RS25965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI801_RS25970	COG0642	Histidine kinase
HI801_RS25975	COG0745	RESPONSE REGULATOR receiver
HI801_RS25990	COG0837	glucose binding
HI801_RS26000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HI801_RS26010	COG0589	response to stress
HI801_RS26025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HI801_RS26030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI801_RS26040	COG1845	cytochrome c oxidase, subunit III
HI801_RS26065	COG2271	Major facilitator Superfamily
HI801_RS26080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI801_RS26090	COG0765	amino acid transport
HI801_RS26095	COG0010	Belongs to the arginase family
HI801_RS26100	COG2197	response regulator
HI801_RS26125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI801_RS26130	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS26140	COG0583	DNA-binding transcription factor activity
HI801_RS26150	COG2814	Major facilitator Superfamily
HI801_RS26165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI801_RS26225	COG1012	belongs to the aldehyde dehydrogenase family
HI801_RS26230	COG0473	3-isopropylmalate dehydrogenase activity
HI801_RS26240	COG2271	Major facilitator Superfamily
HI801_RS26245	COG2721	sulfolactate sulfo-lyase activity
HI801_RS26255	COG1475	DNA binding
HI801_RS26265	COG3969	phosphoadenosine phosphosulfate
HI801_RS26275	COG3039	Transposase
HI801_RS26285	COG0784	Response regulator, receiver
HI801_RS26285	COG2205	protein histidine kinase activity
HI801_RS26290	COG4251	negative regulation of phosphorylation
HI801_RS26290	COG3706	GGDEF domain
HI801_RS26290	COG2203	Gaf domain
HI801_RS26290	COG5001	Diguanylate cyclase
HI801_RS26310	COG2801	Transposase and inactivated derivatives
HI801_RS26330	COG4213	ABC transporter substrate-binding protein
HI801_RS26335	COG1129	ABC transporter
HI801_RS26340	COG4214	carbohydrate transport
HI801_RS26345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI801_RS26350	COG1609	Transcriptional regulator
HI801_RS26435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI801_RS26445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI801_RS26460	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HI801_RS26485	COG2204	response regulator
HI801_RS26505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HI801_RS26525	COG2205	protein histidine kinase activity
HI801_RS26535	COG2252	PERMEase