locus-tag	class	description
CCY86_RS00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCY86_RS00010	COG0594	ribonuclease P activity
CCY86_RS00015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CCY86_RS00020	COG0706	membrane insertase activity
CCY86_RS00025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CCY86_RS00045	COG1408	metallophosphoesterase
CCY86_RS00055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCY86_RS00065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCY86_RS00070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS00075	COG1309	transcriptional regulator
CCY86_RS00090	COG3384	dioxygenase
CCY86_RS00095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCY86_RS00105	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CCY86_RS00110	COG0745	RESPONSE REGULATOR receiver
CCY86_RS00120	COG3622	Belongs to the hyi family
CCY86_RS00135	COG1966	Carbon starvation protein
CCY86_RS00140	COG2879	small protein
CCY86_RS00160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCY86_RS00170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCY86_RS00205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCY86_RS00210	COG1595	DNA-templated transcription, initiation
CCY86_RS00240	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CCY86_RS00265	COG1475	DNA binding
CCY86_RS00290	COG0745	RESPONSE REGULATOR receiver
CCY86_RS00300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS00370	COG3781	membrane
CCY86_RS00375	COG0840	transmembrane signaling receptor activity
CCY86_RS00390	COG0765	amino acid transport
CCY86_RS00395	COG1126	abc transporter atp-binding protein
CCY86_RS00400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS00420	COG0642	Histidine kinase
CCY86_RS00440	COG2814	Major facilitator Superfamily
CCY86_RS00460	COG1959	2 iron, 2 sulfur cluster binding
CCY86_RS00475	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CCY86_RS00485	COG0745	RESPONSE REGULATOR receiver
CCY86_RS00490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCY86_RS00505	COG1335	isochorismatase
CCY86_RS00510	COG2197	response regulator
CCY86_RS00515	COG2200	EAL domain
CCY86_RS00525	COG2205	protein histidine kinase activity
CCY86_RS00530	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CCY86_RS00535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CCY86_RS00540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CCY86_RS00555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCY86_RS00570	COG1116	anion transmembrane transporter activity
CCY86_RS00580	COG1254	Belongs to the acylphosphatase family
CCY86_RS00590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCY86_RS00595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCY86_RS00600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CCY86_RS00605	COG2894	cell division
CCY86_RS00610	COG0850	regulation of cytokinetic process
CCY86_RS00615	COG0737	Belongs to the 5'-nucleotidase family
CCY86_RS00625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCY86_RS00645	COG0642	Histidine kinase
CCY86_RS00660	COG2154	pterin-4-alpha-carbinolamine dehydratase
CCY86_RS00665	COG3186	Phenylalanine-4-hydroxylase
CCY86_RS00680	COG2423	ornithine cyclodeaminase activity
CCY86_RS00685	COG3047	cAMP biosynthetic process
CCY86_RS00695	COG2217	Heavy metal translocating P-type atpase
CCY86_RS00700	COG0789	Transcriptional regulator
CCY86_RS00705	COG2267	carboxylic ester hydrolase activity
CCY86_RS00710	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CCY86_RS00780	COG0583	DNA-binding transcription factor activity
CCY86_RS00785	COG3530	Putative quorum-sensing-regulated virulence factor
CCY86_RS00805	COG0445	tRNA wobble uridine modification
CCY86_RS00810	COG0357	Ribosomal RNA small subunit methyltransferase G
CCY86_RS00815	COG1192	Involved in chromosome partitioning
CCY86_RS00820	COG1475	DNA binding
CCY86_RS00830	COG0356	it plays a direct role in the translocation of protons across the membrane
CCY86_RS00840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCY86_RS00845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCY86_RS00850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCY86_RS00855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCY86_RS00860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCY86_RS00865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCY86_RS00880	COG1832	CoA-binding protein
CCY86_RS00900	COG0625	glutathione transferase activity
CCY86_RS00935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CCY86_RS00940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCY86_RS00945	COG0506	proline dehydrogenase activity
CCY86_RS00945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCY86_RS00945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCY86_RS00950	COG0683	leucine binding
CCY86_RS00960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CCY86_RS00965	COG1297	OPT oligopeptide transporter protein
CCY86_RS00975	COG3220	belongs to the UPF0276 family
CCY86_RS00985	COG1760	l-serine dehydratase
CCY86_RS00990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCY86_RS00990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCY86_RS00995	COG0509	glycine decarboxylation via glycine cleavage system
CCY86_RS01000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CCY86_RS01020	COG0210	DNA helicase
CCY86_RS01055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCY86_RS01060	COG0469	pyruvate kinase activity
CCY86_RS01070	COG2084	Dehydrogenase
CCY86_RS01075	COG3622	Belongs to the hyi family
CCY86_RS01080	COG3960	tartronate-semialdehyde synthase activity
CCY86_RS01085	COG0583	DNA-binding transcription factor activity
CCY86_RS01100	COG1739	Uncharacterized protein family UPF0029
CCY86_RS01110	COG1301	dicarboxylic acid transport
CCY86_RS01115	COG4266	Belongs to the allantoicase family
CCY86_RS01125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCY86_RS01150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCY86_RS01165	COG0792	nuclease activity
CCY86_RS01180	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCY86_RS01185	COG0697	spore germination
CCY86_RS01190	COG4654	Cytochrome c, class I
CCY86_RS01215	COG2010	Cytochrome c
CCY86_RS01220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCY86_RS01225	COG0737	Belongs to the 5'-nucleotidase family
CCY86_RS01245	COG0493	'glutamate synthase
CCY86_RS01270	COG0457	Tetratricopeptide repeat
CCY86_RS01285	COG0529	Catalyzes the synthesis of activated sulfate
CCY86_RS01380	COG0583	DNA-binding transcription factor activity
CCY86_RS01410	COG0529	Catalyzes the synthesis of activated sulfate
CCY86_RS01415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCY86_RS01430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCY86_RS01435	COG3251	PFAM MbtH domain protein
CCY86_RS01440	COG0534	Mate efflux family protein
CCY86_RS01480	COG1733	regulation of RNA biosynthetic process
CCY86_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCY86_RS01510	COG3483	tryptophan 2,3-dioxygenase activity
CCY86_RS01570	COG5001	Diguanylate cyclase
CCY86_RS01570	COG4251	negative regulation of phosphorylation
CCY86_RS01570	COG3706	GGDEF domain
CCY86_RS01570	COG2203	Gaf domain
CCY86_RS01575	COG0671	phosphoesterase, PA-phosphatase related
CCY86_RS01585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCY86_RS01595	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS01605	COG0840	transmembrane signaling receptor activity
CCY86_RS01630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCY86_RS01640	COG3284	Transcriptional regulator
CCY86_RS01650	COG4303	Ethanolamine ammonia lyase large subunit
CCY86_RS01655	COG4302	ethanolamine ammonia-lyase activity
CCY86_RS01660	COG2925	Exonuclease
CCY86_RS01770	COG1522	sequence-specific DNA binding
CCY86_RS01810	COG0475	glutathione-regulated potassium exporter activity
CCY86_RS01810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCY86_RS01895	COG0789	Transcriptional regulator
CCY86_RS01920	COG2205	protein histidine kinase activity
CCY86_RS01920	COG0784	Response regulator, receiver
CCY86_RS01925	COG2197	response regulator
CCY86_RS01930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CCY86_RS01965	COG2814	Major facilitator Superfamily
CCY86_RS01970	COG0668	transmembrane transport
CCY86_RS01990	COG0745	RESPONSE REGULATOR receiver
CCY86_RS01995	COG2205	protein histidine kinase activity
CCY86_RS02020	COG2942	2-epimerase
CCY86_RS02025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CCY86_RS02050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCY86_RS02065	COG0395	ABC-type sugar transport system, permease component
CCY86_RS02075	COG3842	ATPase activity
CCY86_RS02090	COG1349	DNA-binding transcription factor activity
CCY86_RS02145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCY86_RS02165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCY86_RS02170	COG0081	regulation of translation
CCY86_RS02175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCY86_RS02180	COG0222	ribosome binding
CCY86_RS02185	COG0085	RNA polymerase activity
CCY86_RS02190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCY86_RS02195	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CCY86_RS02200	COG3234	Protein of unknown function (DUF1175)
CCY86_RS02205	COG2373	Large extracellular alpha-helical protein
CCY86_RS02210	COG5445	Predicted secreted protein (DUF2300)
CCY86_RS02215	COG4676	Protein conserved in bacteria
CCY86_RS02220	COG4676	Protein conserved in bacteria
CCY86_RS02230	COG0514	ATP-dependent DNA helicase (RecQ)
CCY86_RS02235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCY86_RS02240	COG0049	tRNA binding
CCY86_RS02250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCY86_RS02255	COG0051	transcription antitermination factor activity, RNA binding
CCY86_RS02260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCY86_RS02265	COG0088	Forms part of the polypeptide exit tunnel
CCY86_RS02270	COG0089	rRNA binding
CCY86_RS02275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCY86_RS02280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCY86_RS02285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCY86_RS02290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCY86_RS02295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCY86_RS02300	COG0255	Belongs to the universal ribosomal protein uL29 family
CCY86_RS02305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCY86_RS02310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCY86_RS02315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCY86_RS02320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCY86_RS02325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCY86_RS02330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCY86_RS02335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCY86_RS02340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCY86_RS02345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCY86_RS02350	COG1841	ribosomal large subunit assembly
CCY86_RS02355	COG0200	Binds to the 23S rRNA
CCY86_RS02360	COG0201	protein transport
CCY86_RS02370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCY86_RS02375	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCY86_RS02380	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCY86_RS02385	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCY86_RS02390	COG0202	RNA polymerase activity
CCY86_RS02395	COG0203	ribosomal protein L17
CCY86_RS02405	COG4232	protein-disulfide reductase activity
CCY86_RS02415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCY86_RS02425	COG1333	cytochrome c biogenesis protein
CCY86_RS02430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCY86_RS02450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CCY86_RS02455	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CCY86_RS02470	COG1965	Belongs to the frataxin family
CCY86_RS02505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCY86_RS02510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCY86_RS02515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCY86_RS02520	COG3047	cAMP biosynthetic process
CCY86_RS02530	COG0070	glutamate synthase
CCY86_RS02530	COG0067	glutamate synthase
CCY86_RS02530	COG0069	glutamate synthase activity
CCY86_RS02545	COG1127	ABC transporter
CCY86_RS02550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCY86_RS02555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCY86_RS02575	COG1131	(ABC) transporter
CCY86_RS02580	COG0842	Transport permease protein
CCY86_RS02590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCY86_RS02595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCY86_RS02600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCY86_RS02605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCY86_RS02610	COG0131	Imidazoleglycerol-phosphate dehydratase
CCY86_RS02615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCY86_RS02620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCY86_RS02625	COG0107	imidazoleglycerol-phosphate synthase activity
CCY86_RS02630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCY86_RS02635	COG0140	phosphoribosyl-ATP diphosphatase activity
CCY86_RS02645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCY86_RS02650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCY86_RS02655	COG0805	protein transport
CCY86_RS02660	COG3842	ATPase activity
CCY86_RS02670	COG1840	ABC-type Fe3 transport system, periplasmic component
CCY86_RS02690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS02695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCY86_RS02700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCY86_RS02705	COG1970	mechanosensitive ion channel activity
CCY86_RS02710	COG0723	plastoquinol--plastocyanin reductase activity
CCY86_RS02715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CCY86_RS02720	COG2857	Cytochrome c1
CCY86_RS02725	COG0625	glutathione transferase activity
CCY86_RS02730	COG2969	positive regulation of protein catabolic process
CCY86_RS02750	COG0405	Gamma-glutamyltransferase
CCY86_RS02755	COG4774	siderophore transport
CCY86_RS02760	COG3712	iron ion homeostasis
CCY86_RS02770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCY86_RS02785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCY86_RS02790	COG0488	(ABC) transporter
CCY86_RS02810	COG2943	transferase activity, transferring hexosyl groups
CCY86_RS02810	COG3416	Protein conserved in bacteria
CCY86_RS02815	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CCY86_RS02830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCY86_RS02835	COG2890	protein-(glutamine-N5) methyltransferase activity
CCY86_RS02845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCY86_RS02850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCY86_RS02860	COG0012	GTP binding
CCY86_RS02885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCY86_RS02895	COG0604	alcohol dehydrogenase
CCY86_RS02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCY86_RS02905	COG1289	transmembrane transporter activity
CCY86_RS02910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCY86_RS02920	COG0134	indole-3-glycerol-phosphate synthase activity
CCY86_RS02925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCY86_RS02935	COG0512	Glutamine amidotransferase of anthranilate synthase
CCY86_RS02945	COG0546	phosphoglycolate phosphatase activity
CCY86_RS02950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCY86_RS02955	COG2967	ApaG domain
CCY86_RS02975	COG2050	protein possibly involved in aromatic compounds catabolism
CCY86_RS02980	COG1024	Enoyl-CoA hydratase
CCY86_RS03015	COG1473	amidohydrolase
CCY86_RS03020	COG0747	negative chemotaxis
CCY86_RS03025	COG0601	transmembrane transport
CCY86_RS03030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCY86_RS03040	COG4608	Belongs to the ABC transporter superfamily
CCY86_RS03045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCY86_RS03055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCY86_RS03055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCY86_RS03060	COG1105	Belongs to the carbohydrate kinase PfkB family
CCY86_RS03065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCY86_RS03065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCY86_RS03070	COG1609	Transcriptional regulator
CCY86_RS03075	COG0243	molybdopterin cofactor binding
CCY86_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS03090	COG0477	Major facilitator Superfamily
CCY86_RS03100	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CCY86_RS03105	COG2001	Belongs to the MraZ family
CCY86_RS03110	COG0275	rRNA processing
CCY86_RS03115	COG3116	cell division
CCY86_RS03125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCY86_RS03130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCY86_RS03135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCY86_RS03140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCY86_RS03150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCY86_RS03155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCY86_RS03160	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCY86_RS03165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCY86_RS03180	COG0678	peroxiredoxin activity
CCY86_RS03185	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CCY86_RS03195	COG0739	heme binding
CCY86_RS03200	COG0653	protein targeting
CCY86_RS03205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCY86_RS03215	COG0494	nUDIX hydrolase
CCY86_RS03220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CCY86_RS03225	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CCY86_RS03230	COG0237	dephospho-CoA kinase activity
CCY86_RS03240	COG1459	type II secretion system
CCY86_RS03250	COG4536	flavin adenine dinucleotide binding
CCY86_RS03260	COG0142	geranyltranstransferase activity
CCY86_RS03265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCY86_RS03270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCY86_RS03275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCY86_RS03280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCY86_RS03290	COG0494	nUDIX hydrolase
CCY86_RS03295	COG0442	prolyl-tRNA aminoacylation
CCY86_RS03300	COG0741	lytic transglycosylase activity
CCY86_RS03310	COG2095	MarC family integral membrane protein
CCY86_RS03315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CCY86_RS03320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCY86_RS03325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCY86_RS03345	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCY86_RS03370	COG1522	sequence-specific DNA binding
CCY86_RS03380	COG0840	transmembrane signaling receptor activity
CCY86_RS03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCY86_RS03425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CCY86_RS03435	COG2264	protein methyltransferase activity
CCY86_RS03445	COG0511	ligase activity, forming carbon-carbon bonds
CCY86_RS03450	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCY86_RS03455	COG3118	belongs to the thioredoxin family
CCY86_RS03465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCY86_RS03470	COG3150	esterase
CCY86_RS03475	COG3161	chorismate lyase activity
CCY86_RS03480	COG0557	exoribonuclease II activity
CCY86_RS03490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCY86_RS03495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCY86_RS03510	COG0284	orotidine-5'-phosphate decarboxylase activity
CCY86_RS03515	COG1230	cation diffusion facilitator family transporter
CCY86_RS03520	COG1546	Belongs to the CinA family
CCY86_RS03520	COG1058	Belongs to the CinA family
CCY86_RS03525	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCY86_RS03535	COG0280	phosphate acetyltransferase
CCY86_RS03535	COG0281	malic enzyme
CCY86_RS03555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCY86_RS03570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCY86_RS03575	COG0583	DNA-binding transcription factor activity
CCY86_RS03580	COG0735	belongs to the Fur family
CCY86_RS03585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCY86_RS03590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCY86_RS03595	COG0495	leucyl-tRNA aminoacylation
CCY86_RS03605	COG1466	dna polymerase III delta subunit
CCY86_RS03610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCY86_RS03615	COG1981	membrane
CCY86_RS03625	COG2204	response regulator
CCY86_RS03630	COG4191	Histidine kinase
CCY86_RS03635	COG4191	Histidine kinase
CCY86_RS03660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCY86_RS03680	COG2814	Major facilitator Superfamily
CCY86_RS03700	COG0482	sulfurtransferase activity
CCY86_RS03705	COG0069	glutamate synthase activity
CCY86_RS03710	COG0625	glutathione transferase activity
CCY86_RS03720	COG3038	cytochrome b561
CCY86_RS03725	COG2353	YceI-like domain
CCY86_RS03730	COG2353	YceI-like domain
CCY86_RS03740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCY86_RS03745	COG1862	Preprotein translocase
CCY86_RS03750	COG0343	queuine tRNA-ribosyltransferase activity
CCY86_RS03755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCY86_RS03760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCY86_RS03800	COG1522	sequence-specific DNA binding
CCY86_RS03805	COG1473	amidohydrolase
CCY86_RS03815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS03820	COG2271	Major facilitator Superfamily
CCY86_RS03825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS03830	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS03835	COG0697	spore germination
CCY86_RS03840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS03865	COG0783	Belongs to the Dps family
CCY86_RS03870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCY86_RS03930	COG0386	Belongs to the glutathione peroxidase family
CCY86_RS03950	COG1346	cytolysis
CCY86_RS03955	COG1380	Effector of murein hydrolase LrgA
CCY86_RS03960	COG0247	lactate metabolic process
CCY86_RS03965	COG0277	FAD linked oxidase domain protein
CCY86_RS03970	COG0277	FAD linked oxidase domain protein
CCY86_RS03980	COG0277	FAD linked oxidase domain protein
CCY86_RS03985	COG2096	Adenosyltransferase
CCY86_RS03990	COG0668	transmembrane transport
CCY86_RS04000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCY86_RS04005	COG0312	modulator of DNA gyrase
CCY86_RS04010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCY86_RS04020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCY86_RS04030	COG1404	Belongs to the peptidase S8 family
CCY86_RS04035	COG1404	Belongs to the peptidase S8 family
CCY86_RS04045	COG0497	DNA recombination
CCY86_RS04050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCY86_RS04055	COG1420	regulation of RNA biosynthetic process
CCY86_RS04065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CCY86_RS04070	COG2986	histidine ammonia-lyase
CCY86_RS04075	COG0010	Belongs to the arginase family
CCY86_RS04080	COG1228	amidohydrolase
CCY86_RS04085	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCY86_RS04105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCY86_RS04120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCY86_RS04125	COG0443	Heat shock 70 kDa protein
CCY86_RS04130	COG0484	heat shock protein binding
CCY86_RS04135	COG0512	Glutamine amidotransferase of anthranilate synthase
CCY86_RS04135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCY86_RS04140	COG1122	ATPase activity
CCY86_RS04145	COG4662	Binding-protein-dependent transport system inner membrane component
CCY86_RS04150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCY86_RS04160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCY86_RS04165	COG0617	tRNA 3'-terminal CCA addition
CCY86_RS04175	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCY86_RS04180	COG0628	permease
CCY86_RS04185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCY86_RS04200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCY86_RS04200	COG2169	Transcriptional regulator
CCY86_RS04220	COG2169	Transcriptional regulator
CCY86_RS04220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCY86_RS04230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCY86_RS04235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCY86_RS04240	COG3008	intermembrane lipid transfer
CCY86_RS04255	COG0586	Pfam SNARE associated Golgi protein
CCY86_RS04265	COG0728	peptidoglycan biosynthetic process
CCY86_RS04270	COG0268	Binds directly to 16S ribosomal RNA
CCY86_RS04280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCY86_RS04285	COG0137	argininosuccinate synthase activity
CCY86_RS04290	COG3123	guanosine phosphorylase activity
CCY86_RS04320	COG0463	Glycosyl transferase, family 2
CCY86_RS04365	COG4964	Belongs to the GSP D family
CCY86_RS04410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS04415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCY86_RS04420	COG1773	rubredoxin
CCY86_RS04435	COG0835	chemotaxis
CCY86_RS04440	COG0840	transmembrane signaling receptor activity
CCY86_RS04445	COG0784	Response regulator, receiver
CCY86_RS04445	COG0643	Histidine kinase
CCY86_RS04445	COG0784	Response regulator, receiver
CCY86_RS04445	COG2198	Histidine kinase
CCY86_RS04445	COG0643	Histidine kinase
CCY86_RS04445	COG2198	Histidine kinase
CCY86_RS04450	COG0415	Belongs to the DNA photolyase family
CCY86_RS04455	COG1187	pseudouridine synthase activity
CCY86_RS04460	COG1678	Uncharacterized ACR, COG1678
CCY86_RS04465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCY86_RS04470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCY86_RS04475	COG0540	Belongs to the ATCase OTCase family
CCY86_RS04490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCY86_RS04545	COG0859	PFAM glycosyl transferase family 9
CCY86_RS04560	COG1538	Outer membrane efflux protein
CCY86_RS04565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCY86_RS04565	COG0425	Belongs to the sulfur carrier protein TusA family
CCY86_RS04570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCY86_RS04595	COG1968	undecaprenyl-diphosphatase activity
CCY86_RS04600	COG1902	pentaerythritol trinitrate reductase activity
CCY86_RS04605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCY86_RS04640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCY86_RS04650	COG0436	Aminotransferase
CCY86_RS04655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCY86_RS04660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCY86_RS04675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCY86_RS04675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCY86_RS04710	COG4970	Tfp pilus assembly protein FimT
CCY86_RS04740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCY86_RS04745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCY86_RS04750	COG4221	oxidoreductase activity
CCY86_RS04755	COG0824	Thioesterase
CCY86_RS04775	COG0823	Involved in the tonB-independent uptake of proteins
CCY86_RS04785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CCY86_RS04790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCY86_RS04795	COG2391	methyltransferase activity
CCY86_RS04805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCY86_RS04830	COG2175	clavaminate synthase activity
CCY86_RS04835	COG0494	nUDIX hydrolase
CCY86_RS04840	COG0390	transport system, permease component
CCY86_RS04845	COG1136	(ABC) transporter
CCY86_RS04865	COG4575	ribosome binding
CCY86_RS04870	COG0450	alkyl hydroperoxide reductase
CCY86_RS04875	COG2252	PERMEase
CCY86_RS04880	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS04890	COG3483	tryptophan 2,3-dioxygenase activity
CCY86_RS04900	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CCY86_RS04905	COG1522	sequence-specific DNA binding
CCY86_RS04915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCY86_RS04920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCY86_RS04930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCY86_RS04935	COG0259	pyridoxamine-phosphate oxidase activity
CCY86_RS04960	COG2982	Protein involved in outer membrane biogenesis
CCY86_RS04965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCY86_RS04970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CCY86_RS04975	COG2703	oxygen carrier activity
CCY86_RS04985	COG3118	belongs to the thioredoxin family
CCY86_RS04990	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS05000	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CCY86_RS05015	COG4681	YaeQ
CCY86_RS05045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCY86_RS05065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCY86_RS05070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCY86_RS05080	COG4804	nuclease activity
CCY86_RS05105	COG0330	HflC and HflK could
CCY86_RS05120	COG0477	Major facilitator Superfamily
CCY86_RS05125	COG0235	Class ii aldolase
CCY86_RS05130	COG1942	4-Oxalocrotonate Tautomerase
CCY86_RS05145	COG0425	Belongs to the sulfur carrier protein TusA family
CCY86_RS05160	COG1280	lysine exporter protein (LysE YggA)
CCY86_RS05175	COG1733	regulation of RNA biosynthetic process
CCY86_RS05185	COG4305	rare lipoprotein A
CCY86_RS05205	COG4383	Mu-like prophage protein gp29
CCY86_RS05230	COG0739	heme binding
CCY86_RS05230	COG1196	nuclear chromosome segregation
CCY86_RS05230	COG0741	lytic transglycosylase activity
CCY86_RS05290	COG0776	regulation of translation
CCY86_RS05325	COG4388	Caudovirus prohead serine protease
CCY86_RS05330	COG4397	Mu-like prophage major head subunit gpT
CCY86_RS05350	COG4386	tail sheath protein
CCY86_RS05415	COG1741	Belongs to the pirin family
CCY86_RS05420	COG1902	pentaerythritol trinitrate reductase activity
CCY86_RS05435	COG0640	Transcriptional regulator
CCY86_RS05460	COG0546	phosphoglycolate phosphatase activity
CCY86_RS05465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCY86_RS05490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCY86_RS05500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCY86_RS05505	COG0287	Prephenate dehydrogenase
CCY86_RS05510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCY86_RS05515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCY86_RS05525	COG0776	regulation of translation
CCY86_RS05535	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CCY86_RS05545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CCY86_RS05550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCY86_RS05565	COG2951	lytic endotransglycosylase activity
CCY86_RS05590	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CCY86_RS05630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCY86_RS05635	COG1061	Type III restriction enzyme res subunit
CCY86_RS05640	COG1002	Type II restriction enzyme, methylase subunits
CCY86_RS05655	COG0582	viral genome integration into host DNA
CCY86_RS05665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCY86_RS05675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCY86_RS05770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS05785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCY86_RS05795	COG0194	GDP metabolic process
CCY86_RS05800	COG0159	tryptophan synthase activity
CCY86_RS05805	COG0133	tryptophan synthase activity
CCY86_RS05830	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCY86_RS05840	COG0583	DNA-binding transcription factor activity
CCY86_RS05905	COG0789	Transcriptional regulator
CCY86_RS05910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCY86_RS05915	COG1253	flavin adenine dinucleotide binding
CCY86_RS05960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS05980	COG0765	amino acid transport
CCY86_RS05985	COG0765	amino acid transport
CCY86_RS05990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS06000	COG1414	Transcriptional regulator
CCY86_RS06010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCY86_RS06025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCY86_RS06030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCY86_RS06045	COG0411	ABC transporter
CCY86_RS06055	COG0683	leucine binding
CCY86_RS06070	COG2342	PFAM TM1410 hypothetical-related protein
CCY86_RS06080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCY86_RS06095	COG0525	valine-tRNA ligase activity
CCY86_RS06100	COG0210	DNA helicase
CCY86_RS06110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCY86_RS06120	COG1611	Belongs to the LOG family
CCY86_RS06125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCY86_RS06125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCY86_RS06130	COG1252	NADH dehydrogenase
CCY86_RS06135	COG0412	Dienelactone hydrolase
CCY86_RS06160	COG1722	exodeoxyribonuclease VII activity
CCY86_RS06165	COG0142	geranyltranstransferase activity
CCY86_RS06170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCY86_RS06175	COG1469	GTP cyclohydrolase I activity
CCY86_RS06180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCY86_RS06185	COG2081	HI0933 family
CCY86_RS06190	COG1610	YqeY-like protein
CCY86_RS06220	COG0426	domain, Protein
CCY86_RS06220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCY86_RS06225	COG0513	Belongs to the DEAD box helicase family
CCY86_RS06230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCY86_RS06235	COG0583	DNA-binding transcription factor activity
CCY86_RS06240	COG1741	Belongs to the pirin family
CCY86_RS06250	COG1054	Belongs to the UPF0176 family
CCY86_RS06280	COG1132	(ABC) transporter
CCY86_RS06295	COG1530	ribonuclease E activity
CCY86_RS06300	COG0424	maF-like protein
CCY86_RS06310	COG0799	negative regulation of ribosome biogenesis
CCY86_RS06320	COG0408	coproporphyrinogen oxidase activity
CCY86_RS06325	COG0151	Belongs to the GarS family
CCY86_RS06330	COG0217	transcriptional regulatory protein
CCY86_RS06335	COG0433	COG0433 Predicted ATPase
CCY86_RS06340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCY86_RS06345	COG0697	spore germination
CCY86_RS06355	COG1803	Methylglyoxal synthase
CCY86_RS06400	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCY86_RS06405	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCY86_RS06410	COG1129	ABC transporter
CCY86_RS06415	COG2814	Major facilitator Superfamily
CCY86_RS06420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCY86_RS06425	COG1984	allophanate hydrolase subunit 2
CCY86_RS06430	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCY86_RS06445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CCY86_RS06450	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CCY86_RS06465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCY86_RS06470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCY86_RS06475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CCY86_RS06485	COG4991	sh3 domain protein
CCY86_RS06485	COG3064	Membrane
CCY86_RS06485	COG0515	serine threonine protein kinase
CCY86_RS06490	COG1561	YicC-like family, N-terminal region
CCY86_RS06495	COG0194	GDP metabolic process
CCY86_RS06500	COG1758	RNA polymerase activity
CCY86_RS06505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCY86_RS06535	COG1652	LysM domain
CCY86_RS06545	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCY86_RS06550	COG0308	aminopeptidase N
CCY86_RS06560	COG0280	phosphate acetyltransferase
CCY86_RS06560	COG0281	malic enzyme
CCY86_RS06570	COG3648	Uricase
CCY86_RS06570	COG3195	allantoin biosynthetic process
CCY86_RS06585	COG2233	PERMEase
CCY86_RS06595	COG2351	hydroxyisourate hydrolase activity
CCY86_RS06615	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CCY86_RS06630	COG1064	alcohol dehydrogenase
CCY86_RS06645	COG0583	DNA-binding transcription factor activity
CCY86_RS06660	COG2119	membrane
CCY86_RS06665	COG0402	S-adenosylhomocysteine deaminase activity
CCY86_RS06670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCY86_RS06680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CCY86_RS06695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCY86_RS06700	COG2011	ABC-type metal ion transport system permease component
CCY86_RS06720	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS06725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS06760	COG0228	four-way junction DNA binding
CCY86_RS06765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCY86_RS06770	COG0336	Belongs to the RNA methyltransferase TrmD family
CCY86_RS06775	COG0335	large ribosomal subunit rRNA binding
CCY86_RS06785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CCY86_RS06795	COG1162	GTPase activity
CCY86_RS06800	COG0501	Belongs to the peptidase M48B family
CCY86_RS06805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCY86_RS06810	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCY86_RS06815	COG3028	Belongs to the UPF0307 family
CCY86_RS06820	COG0312	modulator of DNA gyrase
CCY86_RS06830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCY86_RS06840	COG0861	Integral membrane protein TerC family
CCY86_RS06850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCY86_RS06855	COG0513	Belongs to the DEAD box helicase family
CCY86_RS06925	COG0582	viral genome integration into host DNA
CCY86_RS06960	COG0488	(ABC) transporter
CCY86_RS07000	COG1620	l-lactate permease
CCY86_RS07020	COG0625	glutathione transferase activity
CCY86_RS07025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCY86_RS07035	COG0697	spore germination
CCY86_RS07040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCY86_RS07045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCY86_RS07050	COG0326	Molecular chaperone. Has ATPase activity
CCY86_RS07120	COG0778	Nitroreductase
CCY86_RS07125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCY86_RS07130	COG2878	Part of a membrane complex involved in electron transport
CCY86_RS07135	COG1309	transcriptional regulator
CCY86_RS07150	COG0556	nucleotide-excision repair
CCY86_RS07160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCY86_RS07165	COG1609	Transcriptional regulator
CCY86_RS07170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCY86_RS07175	COG1129	ABC transporter
CCY86_RS07190	COG1104	cysteine desulfurase activity
CCY86_RS07210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCY86_RS07215	COG0443	Heat shock 70 kDa protein
CCY86_RS07235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCY86_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS07250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCY86_RS07270	COG1322	Protein conserved in bacteria
CCY86_RS07285	COG0746	molybdenum cofactor guanylyltransferase activity
CCY86_RS07290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCY86_RS07295	COG1530	ribonuclease E activity
CCY86_RS07305	COG0546	phosphoglycolate phosphatase activity
CCY86_RS07315	COG0616	signal peptide processing
CCY86_RS07315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCY86_RS07325	COG0424	maF-like protein
CCY86_RS07330	COG1399	metal-binding, possibly nucleic acid-binding protein
CCY86_RS07335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCY86_RS07340	COG0416	fatty acid biosynthetic process
CCY86_RS07345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCY86_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCY86_RS07365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCY86_RS07390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCY86_RS07400	COG0481	GTPase activity
CCY86_RS07405	COG0681	Belongs to the peptidase S26 family
CCY86_RS07415	COG0571	ribonuclease III activity
CCY86_RS07420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCY86_RS07425	COG1381	Involved in DNA repair and RecF pathway recombination
CCY86_RS07430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CCY86_RS07435	COG0736	holo-[acyl-carrier-protein] synthase activity
CCY86_RS07445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCY86_RS07455	COG0322	excinuclease ABC activity
CCY86_RS07480	COG0745	RESPONSE REGULATOR receiver
CCY86_RS07490	COG5002	protein histidine kinase activity
CCY86_RS07500	COG0745	RESPONSE REGULATOR receiver
CCY86_RS07510	COG2186	Transcriptional regulator
CCY86_RS07520	COG2271	Major facilitator Superfamily
CCY86_RS07530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS07540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS07590	COG0583	DNA-binding transcription factor activity
CCY86_RS07615	COG2124	cytochrome p450
CCY86_RS07640	COG0583	DNA-binding transcription factor activity
CCY86_RS07645	COG2855	membrane
CCY86_RS07670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCY86_RS07675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCY86_RS07690	COG1136	(ABC) transporter
CCY86_RS07695	COG0084	hydrolase, TatD family'
CCY86_RS07705	COG2308	Evidence 4 Homologs of previously reported genes of
CCY86_RS07725	COG2267	carboxylic ester hydrolase activity
CCY86_RS07730	COG0504	CTP synthase activity
CCY86_RS07735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCY86_RS07745	COG0148	phosphopyruvate hydratase activity
CCY86_RS07750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCY86_RS07760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCY86_RS07770	COG2833	Protein of unknown function (DUF455)
CCY86_RS07775	COG2267	carboxylic ester hydrolase activity
CCY86_RS07780	COG3011	Protein conserved in bacteria
CCY86_RS07795	COG0492	ferredoxin-NADP+ reductase activity
CCY86_RS07800	COG0613	PHP domain protein
CCY86_RS07805	COG0009	L-threonylcarbamoyladenylate synthase
CCY86_RS07810	COG1994	Peptidase M50
CCY86_RS07815	COG0180	Tryptophanyl-tRNA synthetase
CCY86_RS07820	COG2226	methyltransferase
CCY86_RS07825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS07830	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CCY86_RS07835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCY86_RS07845	COG2850	peptidyl-arginine hydroxylation
CCY86_RS07860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCY86_RS07865	COG0583	DNA-binding transcription factor activity
CCY86_RS07870	COG2814	Major facilitator Superfamily
CCY86_RS07875	COG0656	L-ascorbic acid biosynthetic process
CCY86_RS07905	COG0483	inositol monophosphate 1-phosphatase activity
CCY86_RS07915	COG1045	serine acetyltransferase
CCY86_RS07920	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCY86_RS07940	COG0215	cysteine-tRNA ligase activity
CCY86_RS07945	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CCY86_RS07950	COG0825	malonyl-CoA metabolic process
CCY86_RS07955	COG0037	tRNA processing
CCY86_RS07960	COG0527	aspartate kinase activity
CCY86_RS07975	COG4166	transmembrane transport
CCY86_RS07980	COG4174	ABC transporter (Permease)
CCY86_RS07985	COG4239	(ABC) transporter, permease
CCY86_RS07990	COG4172	Belongs to the ABC transporter superfamily
CCY86_RS07995	COG0791	NLP P60 protein
CCY86_RS08000	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCY86_RS08005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCY86_RS08040	COG0534	Mate efflux family protein
CCY86_RS08050	COG0254	rRNA binding
CCY86_RS08060	COG3228	Belongs to the MtfA family
CCY86_RS08065	COG2197	response regulator
CCY86_RS08070	COG2204	response regulator
CCY86_RS08075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCY86_RS08090	COG1074	ATP-dependent DNA helicase activity
CCY86_RS08100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCY86_RS08105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCY86_RS08110	COG2329	Antibiotic biosynthesis monooxygenase
CCY86_RS08115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCY86_RS08130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCY86_RS08135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCY86_RS08145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCY86_RS08150	COG1309	transcriptional regulator
CCY86_RS08155	COG1902	pentaerythritol trinitrate reductase activity
CCY86_RS08165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CCY86_RS08170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCY86_RS08190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCY86_RS08195	COG0670	Belongs to the BI1 family
CCY86_RS08200	COG0105	UTP biosynthetic process
CCY86_RS08205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCY86_RS08220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCY86_RS08225	COG0124	histidyl-tRNA synthetase
CCY86_RS08240	COG1160	GTP binding
CCY86_RS08245	COG1923	regulation of RNA biosynthetic process
CCY86_RS08250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCY86_RS08255	COG0330	HflC and HflK could
CCY86_RS08260	COG0330	HflC and HflK could
CCY86_RS08270	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CCY86_RS08275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCY86_RS08280	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CCY86_RS08290	COG0557	exoribonuclease II activity
CCY86_RS08295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCY86_RS08300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCY86_RS08305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCY86_RS08310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCY86_RS08315	COG1953	Uracil, thiamine, allantoin
CCY86_RS08330	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CCY86_RS08335	COG0673	inositol 2-dehydrogenase activity
CCY86_RS08340	COG1737	Transcriptional regulator
CCY86_RS08365	COG3657	addiction module killer protein
CCY86_RS08390	COG1129	ABC transporter
CCY86_RS08395	COG4211	Belongs to the binding-protein-dependent transport system permease family
CCY86_RS08405	COG3962	Belongs to the TPP enzyme family
CCY86_RS08415	COG3718	enzyme involved in inositol metabolism
CCY86_RS08425	COG0673	inositol 2-dehydrogenase activity
CCY86_RS08430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCY86_RS08430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCY86_RS08435	COG1643	Atp-dependent helicase
CCY86_RS08460	COG1058	Belongs to the CinA family
CCY86_RS08460	COG1546	Belongs to the CinA family
CCY86_RS08470	COG0174	glutamine synthetase
CCY86_RS08485	COG2204	response regulator
CCY86_RS08495	COG2217	Heavy metal translocating P-type atpase
CCY86_RS08500	COG1653	transport
CCY86_RS08510	COG1175	transmembrane transport
CCY86_RS08515	COG0395	ABC-type sugar transport system, permease component
CCY86_RS08520	COG3842	ATPase activity
CCY86_RS08525	COG0584	glycerophosphoryl diester phosphodiesterase
CCY86_RS08530	COG0567	Dehydrogenase, E1 component
CCY86_RS08535	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCY86_RS08540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCY86_RS08545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCY86_RS08555	COG2217	Heavy metal translocating P-type atpase
CCY86_RS08565	COG3278	Belongs to the heme-copper respiratory oxidase family
CCY86_RS08600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCY86_RS08610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCY86_RS08620	COG0779	Required for maturation of 30S ribosomal subunits
CCY86_RS08625	COG0195	Participates in both transcription termination and antitermination
CCY86_RS08625	COG2251	uridine kinase activity
CCY86_RS08630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCY86_RS08635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCY86_RS08640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCY86_RS08645	COG2814	Major facilitator Superfamily
CCY86_RS08650	COG1566	PFAM secretion protein HlyD family protein
CCY86_RS08665	COG1217	gtp-binding protein TYPA
CCY86_RS08675	COG1024	Enoyl-CoA hydratase
CCY86_RS08680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCY86_RS08695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCY86_RS08715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCY86_RS08730	COG0360	Binds together with S18 to 16S ribosomal RNA
CCY86_RS08740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCY86_RS08745	COG0359	binds to the 23S rRNA
CCY86_RS08750	COG0305	Participates in initiation and elongation during chromosome replication
CCY86_RS08760	COG0306	phosphate transporter
CCY86_RS08765	COG0791	NLP P60 protein
CCY86_RS08775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CCY86_RS08780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCY86_RS08785	COG0726	polysaccharide deacetylase
CCY86_RS08805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCY86_RS08810	COG2076	Multidrug Resistance protein
CCY86_RS08815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCY86_RS08825	COG0436	Aminotransferase
CCY86_RS08840	COG1573	uracil-dna glycosylase
CCY86_RS08845	COG0303	'Molybdopterin
CCY86_RS08850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CCY86_RS08855	COG0314	molybdopterin synthase activity
CCY86_RS08860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCY86_RS08870	COG0542	response to heat
CCY86_RS08875	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CCY86_RS08880	COG0431	NADPH-dependent FMN reductase
CCY86_RS08885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCY86_RS08890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCY86_RS08895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCY86_RS08900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCY86_RS08905	COG1116	anion transmembrane transporter activity
CCY86_RS08925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CCY86_RS08930	COG4208	sulfate ABC transporter
CCY86_RS08935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCY86_RS08940	COG0583	DNA-binding transcription factor activity
CCY86_RS08955	COG3275	phosphorelay sensor kinase activity
CCY86_RS08970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCY86_RS08990	COG2224	Isocitrate lyase
CCY86_RS09000	COG0583	DNA-binding transcription factor activity
CCY86_RS09010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCY86_RS09025	COG1214	PFAM Peptidase M22, glycoprotease
CCY86_RS09030	COG0456	acetyltransferase
CCY86_RS09035	COG1573	uracil-dna glycosylase
CCY86_RS09045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCY86_RS09055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CCY86_RS09060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCY86_RS09065	COG0488	(ABC) transporter
CCY86_RS09075	COG1446	asparaginase
CCY86_RS09080	COG4172	Belongs to the ABC transporter superfamily
CCY86_RS09085	COG0747	negative chemotaxis
CCY86_RS09090	COG0601	transmembrane transport
CCY86_RS09095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCY86_RS09130	COG2890	protein-(glutamine-N5) methyltransferase activity
CCY86_RS09140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCY86_RS09145	COG1393	Belongs to the ArsC family
CCY86_RS09155	COG2171	N-acyltransferase activity
CCY86_RS09185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCY86_RS09190	COG0242	peptide deformylase activity
CCY86_RS09200	COG1187	pseudouridine synthase activity
CCY86_RS09205	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CCY86_RS09210	COG0024	Methionine aminopeptidase
CCY86_RS09215	COG0052	Belongs to the universal ribosomal protein uS2 family
CCY86_RS09220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCY86_RS09225	COG0528	UMP kinase activity
CCY86_RS09230	COG0233	cytoplasmic translational termination
CCY86_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCY86_RS09240	COG0575	Belongs to the CDS family
CCY86_RS09245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCY86_RS09250	COG0750	zinc metalloprotease
CCY86_RS09265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCY86_RS09270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCY86_RS09275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCY86_RS09280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCY86_RS09285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCY86_RS09290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCY86_RS09310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CCY86_RS09325	COG0330	HflC and HflK could
CCY86_RS09330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCY86_RS09335	COG2867	negative regulation of translational initiation
CCY86_RS09340	COG2914	Belongs to the UPF0125 (RnfH) family
CCY86_RS09350	COG0697	spore germination
CCY86_RS09365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCY86_RS09365	COG0519	Catalyzes the synthesis of GMP from XMP
CCY86_RS09405	COG0583	DNA-binding transcription factor activity
CCY86_RS09410	COG3485	protocatechuate 3,4-dioxygenase
CCY86_RS09415	COG3485	protocatechuate 3,4-dioxygenase
CCY86_RS09440	COG0583	DNA-binding transcription factor activity
CCY86_RS09450	COG3550	peptidyl-serine autophosphorylation
CCY86_RS09460	COG0602	queuosine metabolic process
CCY86_RS09465	COG0720	synthase
CCY86_RS09475	COG1619	proteins homologs of microcin C7 resistance protein MccF
CCY86_RS09480	COG0488	(ABC) transporter
CCY86_RS09510	COG3387	PFAM Glycoside hydrolase 15-related
CCY86_RS09520	COG0840	transmembrane signaling receptor activity
CCY86_RS09530	COG3320	Male sterility
CCY86_RS09530	COG1022	Amp-dependent synthetase and ligase
CCY86_RS09535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CCY86_RS09570	COG3045	CreA protein
CCY86_RS09575	COG0583	DNA-binding transcription factor activity
CCY86_RS09600	COG0778	Nitroreductase
CCY86_RS09615	COG0583	DNA-binding transcription factor activity
CCY86_RS09620	COG4948	Mandelate Racemase Muconate Lactonizing
CCY86_RS09635	COG4638	Rieske (2fe-2S)
CCY86_RS09640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CCY86_RS09645	COG0633	Ferredoxin
CCY86_RS09645	COG0543	2 iron, 2 sulfur cluster binding
CCY86_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS09660	COG0156	8-amino-7-oxononanoate synthase activity
CCY86_RS09665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCY86_RS09680	COG3739	integral membrane protein
CCY86_RS09705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCY86_RS09735	COG1196	nuclear chromosome segregation
CCY86_RS09765	COG0833	amino acid
CCY86_RS09770	COG0833	amino acid
CCY86_RS09780	COG1335	isochorismatase
CCY86_RS09785	COG0183	Belongs to the thiolase family
CCY86_RS09790	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS09810	COG2130	NADP-dependent
CCY86_RS09830	COG0596	Alpha beta hydrolase
CCY86_RS09840	COG0657	acetylesterase activity
CCY86_RS09875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCY86_RS09880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCY86_RS09885	COG0470	DNA polymerase III
CCY86_RS09895	COG0084	hydrolase, TatD family'
CCY86_RS09910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCY86_RS09915	COG1609	Transcriptional regulator
CCY86_RS09920	COG1840	ABC-type Fe3 transport system, periplasmic component
CCY86_RS09925	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCY86_RS09930	COG4208	sulfate ABC transporter
CCY86_RS09935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCY86_RS09940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCY86_RS10070	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS10075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCY86_RS10080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCY86_RS10085	COG2917	probably involved in intracellular septation
CCY86_RS10095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCY86_RS10125	COG0642	Histidine kinase
CCY86_RS10130	COG3842	ATPase activity
CCY86_RS10140	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCY86_RS10145	COG1177	transmembrane transport
CCY86_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS10155	COG0583	DNA-binding transcription factor activity
CCY86_RS10160	COG0535	radical SAM domain protein
CCY86_RS10180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCY86_RS10180	COG0047	phosphoribosylformylglycinamidine synthase activity
CCY86_RS10190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCY86_RS10195	COG0166	Belongs to the GPI family
CCY86_RS10200	COG4181	ATPase activity
CCY86_RS10210	COG0681	Belongs to the peptidase S26 family
CCY86_RS10215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCY86_RS10230	COG0776	regulation of translation
CCY86_RS10235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCY86_RS10240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCY86_RS10245	COG0740	serine-type endopeptidase activity
CCY86_RS10250	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCY86_RS10255	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CCY86_RS10255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS10280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS10285	COG1562	ergosterol biosynthetic process
CCY86_RS10315	COG0450	alkyl hydroperoxide reductase
CCY86_RS10320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCY86_RS10325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCY86_RS10330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCY86_RS10335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCY86_RS10345	COG0560	Phosphoserine phosphatase
CCY86_RS10350	COG4804	nuclease activity
CCY86_RS10365	COG0183	Belongs to the thiolase family
CCY86_RS10370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCY86_RS10375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCY86_RS10385	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS10390	COG0183	Belongs to the thiolase family
CCY86_RS10395	COG3243	poly(R)-hydroxyalkanoic acid synthase
CCY86_RS10410	COG0564	pseudouridine synthase activity
CCY86_RS10420	COG1199	ATP-dependent helicase activity
CCY86_RS10435	COG2183	response to ionizing radiation
CCY86_RS10450	COG3158	transport of potassium into the cell
CCY86_RS10460	COG0167	dihydroorotate dehydrogenase activity
CCY86_RS10475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CCY86_RS10480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CCY86_RS10505	COG1414	Transcriptional regulator
CCY86_RS10520	COG0824	Thioesterase
CCY86_RS10530	COG0123	including yeast histone deacetylase and acetoin utilization protein
CCY86_RS10545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCY86_RS10555	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCY86_RS10560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCY86_RS10575	COG4566	intracellular signal transduction
CCY86_RS10580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCY86_RS10585	COG0339	signal peptide processing
CCY86_RS10590	COG0402	S-adenosylhomocysteine deaminase activity
CCY86_RS10600	COG1846	Transcriptional regulator
CCY86_RS10620	COG0531	amino acid
CCY86_RS10625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCY86_RS10640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCY86_RS10645	COG2207	Transcriptional regulator
CCY86_RS10740	COG0776	regulation of translation
CCY86_RS10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCY86_RS10745	COG0072	phenylalanine-tRNA ligase activity
CCY86_RS10750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCY86_RS10755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCY86_RS10760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCY86_RS10765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCY86_RS10770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCY86_RS10780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCY86_RS10785	COG0251	oxidation-reduction process
CCY86_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS10810	COG4566	intracellular signal transduction
CCY86_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS10825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCY86_RS10830	COG0545	Peptidyl-prolyl cis-trans isomerase
CCY86_RS10835	COG0477	Major facilitator Superfamily
CCY86_RS10850	COG2267	carboxylic ester hydrolase activity
CCY86_RS10860	COG1295	ribonuclease BN
CCY86_RS10875	COG0277	FAD linked oxidase domain protein
CCY86_RS10945	COG0248	Ppx GppA phosphatase
CCY86_RS10950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CCY86_RS10960	COG0745	RESPONSE REGULATOR receiver
CCY86_RS10970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCY86_RS10975	COG0581	inorganic phosphate transmembrane transporter activity
CCY86_RS10980	COG0573	inorganic phosphate transmembrane transporter activity
CCY86_RS10985	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCY86_RS10990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCY86_RS10995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCY86_RS11000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCY86_RS11005	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CCY86_RS11010	COG1534	Rna-binding protein
CCY86_RS11020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCY86_RS11025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCY86_RS11035	COG0505	Belongs to the CarA family
CCY86_RS11040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCY86_RS11045	COG0741	lytic transglycosylase activity
CCY86_RS11045	COG1388	LysM domain
CCY86_RS11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCY86_RS11055	COG2226	methyltransferase
CCY86_RS11060	COG0328	RNA-DNA hybrid ribonuclease activity
CCY86_RS11100	COG0589	response to stress
CCY86_RS11115	COG2304	oxidoreductase activity
CCY86_RS11170	COG0582	viral genome integration into host DNA
CCY86_RS11180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCY86_RS11225	COG2072	flavoprotein involved in K transport
CCY86_RS11230	COG0601	transmembrane transport
CCY86_RS11235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCY86_RS11240	COG0444	Belongs to the ABC transporter superfamily
CCY86_RS11245	COG4608	Belongs to the ABC transporter superfamily
CCY86_RS11250	COG0747	negative chemotaxis
CCY86_RS11290	COG0840	transmembrane signaling receptor activity
CCY86_RS11300	COG2197	response regulator
CCY86_RS11330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCY86_RS11335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCY86_RS11340	COG0697	spore germination
CCY86_RS11355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCY86_RS11360	COG1301	dicarboxylic acid transport
CCY86_RS11400	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CCY86_RS11430	COG1131	(ABC) transporter
CCY86_RS11435	COG0842	Transport permease protein
CCY86_RS11455	COG0285	dihydrofolate synthase activity
CCY86_RS11460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCY86_RS11465	COG0159	tryptophan synthase activity
CCY86_RS11475	COG0133	tryptophan synthase activity
CCY86_RS11480	COG0135	phosphoribosylanthranilate isomerase activity
CCY86_RS11485	COG0101	tRNA pseudouridine synthase activity
CCY86_RS11500	COG0473	3-isopropylmalate dehydrogenase activity
CCY86_RS11505	COG0066	3-isopropylmalate dehydratase activity
CCY86_RS11510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCY86_RS11515	COG0372	Belongs to the citrate synthase family
CCY86_RS11520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CCY86_RS11525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCY86_RS11530	COG1053	succinate dehydrogenase
CCY86_RS11535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CCY86_RS11545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCY86_RS11550	COG0039	L-malate dehydrogenase activity
CCY86_RS11580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CCY86_RS11595	COG0747	negative chemotaxis
CCY86_RS11605	COG2866	Carboxypeptidase
CCY86_RS11610	COG3022	response to hydroperoxide
CCY86_RS11620	COG0436	Aminotransferase
CCY86_RS11625	COG0625	glutathione transferase activity
CCY86_RS11630	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCY86_RS11635	COG1024	Enoyl-CoA hydratase
CCY86_RS11655	COG0583	DNA-binding transcription factor activity
CCY86_RS11670	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS11675	COG0625	glutathione transferase activity
CCY86_RS11700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCY86_RS11705	COG0830	nickel cation binding
CCY86_RS11710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CCY86_RS11715	COG0804	urea catabolic process
CCY86_RS11720	COG0832	Belongs to the urease beta subunit family
CCY86_RS11730	COG0831	urea catabolic process
CCY86_RS11740	COG0829	nickel cation binding
CCY86_RS11775	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS11775	COG2030	dehydratase
CCY86_RS11780	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS11785	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS11805	COG1007	ATP synthesis coupled electron transport
CCY86_RS11820	COG0713	ATP synthesis coupled electron transport
CCY86_RS11830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCY86_RS11835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCY86_RS11840	COG1034	ATP synthesis coupled electron transport
CCY86_RS11855	COG0649	NAD binding
CCY86_RS11860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCY86_RS11865	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCY86_RS11870	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCY86_RS11885	COG0149	triose-phosphate isomerase activity
CCY86_RS11890	COG1063	alcohol dehydrogenase
CCY86_RS11900	COG1185	polyribonucleotide nucleotidyltransferase activity
CCY86_RS11905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCY86_RS11910	COG0683	leucine binding
CCY86_RS11920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCY86_RS11925	COG1183	phosphatidylcholine synthase activity
CCY86_RS11930	COG0688	phosphatidylethanolamine metabolic process
CCY86_RS11935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCY86_RS11945	COG0028	Belongs to the TPP enzyme family
CCY86_RS11980	COG0438	transferase activity, transferring glycosyl groups
CCY86_RS11990	COG1309	transcriptional regulator
CCY86_RS12015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCY86_RS12105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCY86_RS12110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCY86_RS12120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CCY86_RS12125	COG1674	ftsk spoiiie
CCY86_RS12130	COG0492	ferredoxin-NADP+ reductase activity
CCY86_RS12140	COG2860	membrane
CCY86_RS12170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCY86_RS12210	COG0181	hydroxymethylbilane synthase activity
CCY86_RS12215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCY86_RS12245	COG0165	Argininosuccinate lyase
CCY86_RS12255	COG0717	Belongs to the dCTP deaminase family
CCY86_RS12260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CCY86_RS12265	COG2032	superoxide dismutase activity
CCY86_RS12285	COG0437	4 iron, 4 sulfur cluster binding
CCY86_RS12290	COG0243	molybdopterin cofactor binding
CCY86_RS12290	COG3383	formate dehydrogenase (NAD+) activity
CCY86_RS12320	COG0489	protein tyrosine kinase activity
CCY86_RS12325	COG3047	cAMP biosynthetic process
CCY86_RS12325	COG2885	chlorophyll binding
CCY86_RS12330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCY86_RS12330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCY86_RS12340	COG2911	Protein conserved in bacteria
CCY86_RS12355	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCY86_RS12360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCY86_RS12370	COG1492	cobalamin metabolic process
CCY86_RS12390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCY86_RS12400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CCY86_RS12405	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCY86_RS12415	COG1120	ATPase activity
CCY86_RS12425	COG4206	TonB-dependent receptor
CCY86_RS12455	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCY86_RS12460	COG0583	DNA-binding transcription factor activity
CCY86_RS12465	COG0129	dihydroxy-acid dehydratase activity
CCY86_RS12480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCY86_RS12505	COG1648	precorrin-2 dehydrogenase activity
CCY86_RS12505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCY86_RS12510	COG2895	sulfate adenylyltransferase (ATP) activity
CCY86_RS12520	COG0175	sulfate reduction
CCY86_RS12530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCY86_RS12535	COG0730	response to heat
CCY86_RS12540	COG0583	DNA-binding transcription factor activity
CCY86_RS12550	COG2084	Dehydrogenase
CCY86_RS12585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCY86_RS12620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCY86_RS12625	COG1047	Peptidyl-prolyl cis-trans
CCY86_RS12630	COG2003	Belongs to the UPF0758 family
CCY86_RS12635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCY86_RS12640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCY86_RS12645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCY86_RS12655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCY86_RS12670	COG3264	Mechanosensitive ion channel
CCY86_RS12670	COG1511	domain protein
CCY86_RS12680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCY86_RS12680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCY86_RS12685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCY86_RS12690	COG2197	response regulator
CCY86_RS12695	COG0784	Response regulator, receiver
CCY86_RS12695	COG5002	protein histidine kinase activity
CCY86_RS12700	COG0196	riboflavin kinase activity
CCY86_RS12705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCY86_RS12710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CCY86_RS12720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCY86_RS12725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCY86_RS12730	COG0756	dUTP diphosphatase activity
CCY86_RS12735	COG0542	response to heat
CCY86_RS12740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCY86_RS12745	COG1278	Cold shock
CCY86_RS12800	COG1858	cytochrome C peroxidase
CCY86_RS12820	COG0583	DNA-binding transcription factor activity
CCY86_RS12830	COG0477	Major facilitator Superfamily
CCY86_RS12835	COG2259	Doxx family
CCY86_RS12850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS12860	COG2321	neutral zinc metallopeptidase
CCY86_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS12935	COG2610	gluconate transmembrane transporter activity
CCY86_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS12975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCY86_RS12980	COG1570	exodeoxyribonuclease VII activity
CCY86_RS12985	COG0811	peptide transport
CCY86_RS12995	COG1663	tetraacyldisaccharide 4'-kinase activity
CCY86_RS13000	COG2835	tetraacyldisaccharide 4'-kinase activity
CCY86_RS13005	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CCY86_RS13010	COG0563	adenylate kinase activity
CCY86_RS13020	COG0583	DNA-binding transcription factor activity
CCY86_RS13030	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCY86_RS13035	COG0802	atpase or kinase
CCY86_RS13040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCY86_RS13050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCY86_RS13055	COG4974	Belongs to the 'phage' integrase family
CCY86_RS13065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CCY86_RS13075	COG1666	GTP binding
CCY86_RS13080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCY86_RS13110	COG4269	membrane
CCY86_RS13115	COG0459	protein refolding
CCY86_RS13120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCY86_RS13125	COG0443	Heat shock 70 kDa protein
CCY86_RS13140	COG2974	May be involved in recombination
CCY86_RS13200	COG4221	oxidoreductase activity
CCY86_RS13210	COG1309	transcriptional regulator
CCY86_RS13220	COG0840	transmembrane signaling receptor activity
CCY86_RS13225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CCY86_RS13230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CCY86_RS13245	COG2995	paraquat-inducible protein a
CCY86_RS13250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCY86_RS13250	COG3008	intermembrane lipid transfer
CCY86_RS13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCY86_RS13325	COG1228	amidohydrolase
CCY86_RS13330	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CCY86_RS13345	COG0738	Major facilitator superfamily
CCY86_RS13355	COG2027	D-alanyl-D-alanine carboxypeptidase
CCY86_RS13360	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCY86_RS13370	COG0546	phosphoglycolate phosphatase activity
CCY86_RS13380	COG0009	L-threonylcarbamoyladenylate synthase
CCY86_RS13385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCY86_RS13390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCY86_RS13395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCY86_RS13405	COG0469	pyruvate kinase activity
CCY86_RS13410	COG0126	phosphoglycerate kinase activity
CCY86_RS13440	COG0859	PFAM glycosyl transferase family 9
CCY86_RS13450	COG0429	hydrolase of the alpha beta-hydrolase fold
CCY86_RS13460	COG4783	chaperone-mediated protein folding
CCY86_RS13465	COG0315	cyclic pyranopterin monophosphate synthase activity
CCY86_RS13475	COG4969	Belongs to the N-Me-Phe pilin family
CCY86_RS13480	COG4969	Belongs to the N-Me-Phe pilin family
CCY86_RS13485	COG0861	Integral membrane protein TerC family
CCY86_RS13490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CCY86_RS13495	COG0045	succinate-CoA ligase (ADP-forming) activity
CCY86_RS13505	COG2137	regulation of response to DNA damage stimulus
CCY86_RS13510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCY86_RS13530	COG0477	Major facilitator Superfamily
CCY86_RS13555	COG0745	RESPONSE REGULATOR receiver
CCY86_RS13575	COG0513	Belongs to the DEAD box helicase family
CCY86_RS13585	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS13595	COG2030	dehydratase
CCY86_RS13605	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS13620	COG0493	'glutamate synthase
CCY86_RS13620	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCY86_RS13630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCY86_RS13635	COG1702	phosphate starvation-inducible protein PhoH
CCY86_RS13640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCY86_RS13650	COG4535	Mg2 and Co2 transporter CorC
CCY86_RS13655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CCY86_RS13660	COG0752	glycyl-tRNA synthetase alpha subunit
CCY86_RS13670	COG0751	glycine-tRNA ligase activity
CCY86_RS13675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCY86_RS13680	COG0204	Acyl-transferase
CCY86_RS13690	COG0346	lactoylglutathione lyase activity
CCY86_RS13695	COG0697	spore germination
CCY86_RS13700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCY86_RS13705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCY86_RS13710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCY86_RS13715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CCY86_RS13735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCY86_RS13745	COG0006	proline dipeptidase activity
CCY86_RS13750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCY86_RS13755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS13760	COG4680	protein conserved in bacteria
CCY86_RS13775	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CCY86_RS13780	COG0138	bifunctional purine biosynthesis protein purh
CCY86_RS13785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCY86_RS13795	COG0632	four-way junction helicase activity
CCY86_RS13800	COG2255	four-way junction helicase activity
CCY86_RS13815	COG1881	PFAM PEBP family protein
CCY86_RS13820	COG1490	D-aminoacyl-tRNA deacylase activity
CCY86_RS13825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCY86_RS13830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCY86_RS13835	COG0316	Belongs to the HesB IscA family
CCY86_RS13850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCY86_RS13855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCY86_RS13875	COG0418	dihydroorotase activity
CCY86_RS13885	COG0473	3-isopropylmalate dehydrogenase activity
CCY86_RS13890	COG0121	glutamine amidotransferase
CCY86_RS13895	COG1126	abc transporter atp-binding protein
CCY86_RS13900	COG0765	amino acid transport
CCY86_RS13905	COG0765	amino acid transport
CCY86_RS13915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCY86_RS13925	COG5265	(ABC) transporter
CCY86_RS13935	COG1024	Enoyl-CoA hydratase
CCY86_RS13940	COG0183	Belongs to the thiolase family
CCY86_RS13945	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCY86_RS13945	COG1024	Enoyl-CoA hydratase
CCY86_RS13950	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS13965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCY86_RS13970	COG3568	Endonuclease Exonuclease Phosphatase
CCY86_RS13975	COG0494	nUDIX hydrolase
CCY86_RS13985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCY86_RS14010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCY86_RS14025	COG2226	methyltransferase
CCY86_RS14035	COG4178	(ABC) transporter
CCY86_RS14050	COG1238	metal cluster binding
CCY86_RS14055	COG0700	Nucleoside recognition
CCY86_RS14070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCY86_RS14075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCY86_RS14075	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCY86_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS14110	COG3265	gluconokinase activity
CCY86_RS14125	COG2391	methyltransferase activity
CCY86_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS14155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCY86_RS14180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCY86_RS14215	COG0629	single-stranded DNA binding
CCY86_RS14220	COG2814	Major facilitator Superfamily
CCY86_RS14240	COG1280	lysine exporter protein (LysE YggA)
CCY86_RS14245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCY86_RS14250	COG0693	protein deglycase activity
CCY86_RS14275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCY86_RS14290	COG1137	ATPase activity
CCY86_RS14295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CCY86_RS14300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCY86_RS14310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCY86_RS14320	COG1660	Displays ATPase and GTPase activities
CCY86_RS14340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCY86_RS14350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CCY86_RS14355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCY86_RS14365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCY86_RS14370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CCY86_RS14375	COG0193	aminoacyl-tRNA hydrolase activity
CCY86_RS14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCY86_RS14390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCY86_RS14395	COG0742	ribosomal rna small subunit methyltransferase
CCY86_RS14400	COG0612	Peptidase, M16
CCY86_RS14405	COG0612	Peptidase, M16
CCY86_RS14415	COG0625	glutathione transferase activity
CCY86_RS14425	COG3707	response regulator
CCY86_RS14435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCY86_RS14440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCY86_RS14445	COG1116	anion transmembrane transporter activity
CCY86_RS14450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCY86_RS14455	COG1741	Belongs to the pirin family
CCY86_RS14470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCY86_RS14475	COG1999	signal sequence binding
CCY86_RS14480	COG0109	protoheme IX farnesyltransferase activity
CCY86_RS14485	COG1612	heme a metabolic process
CCY86_RS14515	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CCY86_RS14520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCY86_RS14535	COG2226	methyltransferase
CCY86_RS14540	COG1040	competence protein
CCY86_RS14550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCY86_RS14555	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CCY86_RS14560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCY86_RS14570	COG0588	phosphoglycerate mutase activity
CCY86_RS14575	COG0793	Belongs to the peptidase S41A family
CCY86_RS14595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCY86_RS14600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCY86_RS14610	COG0189	ligase activity
CCY86_RS14620	COG0004	ammonium transporteR
CCY86_RS14665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CCY86_RS14685	COG2204	response regulator
CCY86_RS14695	COG1301	dicarboxylic acid transport
CCY86_RS14700	COG3411	Ferredoxin
CCY86_RS14705	COG2945	thiolester hydrolase activity
CCY86_RS14710	COG1686	Belongs to the peptidase S11 family
CCY86_RS14715	COG2921	Belongs to the UPF0250 family
CCY86_RS14720	COG0583	DNA-binding transcription factor activity
CCY86_RS14730	COG0321	lipoyl(octanoyl) transferase activity
CCY86_RS14735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCY86_RS14755	COG0513	Belongs to the DEAD box helicase family
CCY86_RS14775	COG3511	phospholipase C
CCY86_RS14805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCY86_RS14810	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCY86_RS14810	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCY86_RS14815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CCY86_RS14825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CCY86_RS14890	COG2267	carboxylic ester hydrolase activity
CCY86_RS14910	COG0646	methionine synthase
CCY86_RS14910	COG1410	methionine synthase
CCY86_RS14920	COG2197	response regulator
CCY86_RS14940	COG5487	UPF0391 membrane protein
CCY86_RS14950	COG0018	arginyl-trna synthetase
CCY86_RS14960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCY86_RS14965	COG4221	oxidoreductase activity
CCY86_RS14975	COG2329	Antibiotic biosynthesis monooxygenase
CCY86_RS14985	COG0789	Transcriptional regulator
CCY86_RS14990	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS14995	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CCY86_RS15000	COG0288	reversible hydration of carbon dioxide
CCY86_RS15020	COG0183	Belongs to the thiolase family
CCY86_RS15025	COG0300	oxidoreductase activity
CCY86_RS15030	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS15045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCY86_RS15050	COG3012	SEC-C Motif Domain Protein
CCY86_RS15055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCY86_RS15065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CCY86_RS15070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCY86_RS15080	COG4770	biotin carboxylase activity
CCY86_RS15100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCY86_RS15120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCY86_RS15135	COG0596	Alpha beta hydrolase
CCY86_RS15195	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCY86_RS15200	COG1703	isobutyryl-CoA mutase activity
CCY86_RS15200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCY86_RS15200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCY86_RS15240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCY86_RS15250	COG0430	RNA-3'-phosphate cyclase activity
CCY86_RS15255	COG3541	Predicted nucleotidyltransferase
CCY86_RS15260	COG1690	Belongs to the RtcB family
CCY86_RS15270	COG4650	regulator
CCY86_RS15285	COG1254	Belongs to the acylphosphatase family
CCY86_RS15330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCY86_RS15350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCY86_RS15355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCY86_RS15365	COG0037	tRNA processing
CCY86_RS15370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCY86_RS15375	COG0546	phosphoglycolate phosphatase activity
CCY86_RS15375	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCY86_RS15395	COG0493	'glutamate synthase
CCY86_RS15410	COG0842	Transport permease protein
CCY86_RS15415	COG1131	(ABC) transporter
CCY86_RS15420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS15430	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS15435	COG0583	DNA-binding transcription factor activity
CCY86_RS15440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCY86_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS15465	COG2223	nitrite transmembrane transporter activity
CCY86_RS15470	COG0501	Belongs to the peptidase M48B family
CCY86_RS15475	COG0697	spore germination
CCY86_RS15500	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCY86_RS15520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCY86_RS15525	COG4682	membrane
CCY86_RS15530	COG0708	Exodeoxyribonuclease III
CCY86_RS15535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCY86_RS15540	COG2326	polyphosphate kinase activity
CCY86_RS15545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CCY86_RS15560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCY86_RS15580	COG0517	IMP dehydrogenase activity
CCY86_RS15580	COG0516	GMP reductase activity
CCY86_RS15590	COG1522	sequence-specific DNA binding
CCY86_RS15630	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS15665	COG2070	2-Nitropropane dioxygenase
CCY86_RS15670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCY86_RS15685	COG2022	thiamine diphosphate biosynthetic process
CCY86_RS15695	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CCY86_RS15705	COG0351	phosphomethylpyrimidine kinase
CCY86_RS15720	COG1785	Belongs to the alkaline phosphatase family
CCY86_RS15725	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCY86_RS15730	COG1950	PFAM Membrane protein of
CCY86_RS15735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCY86_RS15750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCY86_RS15765	COG0625	glutathione transferase activity
CCY86_RS15770	COG0617	tRNA 3'-terminal CCA addition
CCY86_RS15780	COG3246	L-lysine catabolic process to acetate
CCY86_RS15785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCY86_RS15810	COG2204	response regulator
CCY86_RS15810	COG2204	response regulator
CCY86_RS15815	COG5000	phosphorelay sensor kinase activity
CCY86_RS15825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCY86_RS15830	COG0501	Belongs to the peptidase M48B family
CCY86_RS15840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCY86_RS15850	COG0242	peptide deformylase activity
CCY86_RS15855	COG1652	LysM domain
CCY86_RS15860	COG0758	DNA mediated transformation
CCY86_RS15875	COG0583	DNA-binding transcription factor activity
CCY86_RS15880	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS15885	COG0772	Belongs to the SEDS family
CCY86_RS15890	COG0768	penicillin binding
CCY86_RS15900	COG1792	Involved in formation and maintenance of cell shape
CCY86_RS15905	COG1077	Cell shape determining protein MreB Mrl
CCY86_RS15910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCY86_RS15915	COG0154	amidase activity
CCY86_RS15930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCY86_RS15940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCY86_RS15945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCY86_RS15975	COG0523	cobalamin synthesis protein
CCY86_RS15990	COG0747	negative chemotaxis
CCY86_RS15995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CCY86_RS16000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CCY86_RS16020	COG0592	DNA-directed DNA polymerase activity
CCY86_RS16025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCY86_RS16035	COG1278	Cold shock
CCY86_RS16055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCY86_RS16060	COG0477	Major facilitator Superfamily
CCY86_RS16065	COG4191	Histidine kinase
CCY86_RS16075	COG4377	Putative membrane peptidase family (DUF2324)
CCY86_RS16085	COG5002	protein histidine kinase activity
CCY86_RS16085	COG3447	MASE1 domain protein
CCY86_RS16085	COG5001	Diguanylate cyclase
CCY86_RS16125	COG0038	chloride channel
CCY86_RS16135	COG1881	PFAM PEBP family protein
CCY86_RS16160	COG5002	protein histidine kinase activity
CCY86_RS16175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS16190	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCY86_RS16195	COG0745	RESPONSE REGULATOR receiver
CCY86_RS16200	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCY86_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS16265	COG1024	Enoyl-CoA hydratase
CCY86_RS16270	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS16295	COG0477	Major facilitator Superfamily
CCY86_RS16300	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCY86_RS16305	COG3657	addiction module killer protein
CCY86_RS16310	COG2814	Major facilitator Superfamily
CCY86_RS16335	COG0583	DNA-binding transcription factor activity
CCY86_RS16385	COG0725	ABC transporter, periplasmic molybdate-binding protein
CCY86_RS16400	COG0714	Associated with various cellular activities
CCY86_RS16415	COG0288	reversible hydration of carbon dioxide
CCY86_RS16420	COG0659	secondary active sulfate transmembrane transporter activity
CCY86_RS16455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CCY86_RS16465	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CCY86_RS16470	COG2944	sequence-specific DNA binding
CCY86_RS16555	COG3706	GGDEF domain
CCY86_RS16555	COG5001	Diguanylate cyclase
CCY86_RS16555	COG2203	Gaf domain
CCY86_RS16555	COG4251	negative regulation of phosphorylation
CCY86_RS16580	COG1902	pentaerythritol trinitrate reductase activity
CCY86_RS16630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCY86_RS16675	COG0534	Mate efflux family protein
CCY86_RS16680	COG3251	PFAM MbtH domain protein
CCY86_RS16685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCY86_RS16700	COG0529	Catalyzes the synthesis of activated sulfate
CCY86_RS16810	COG0531	amino acid
CCY86_RS16815	COG0534	Mate efflux family protein
CCY86_RS16830	COG2197	response regulator
CCY86_RS16840	COG0726	polysaccharide deacetylase
CCY86_RS16840	COG1649	PFAM Uncharacterised BCR, COG1649
CCY86_RS16845	COG1215	transferase activity, transferring glycosyl groups
CCY86_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS16865	COG2274	protein secretion by the type I secretion system
CCY86_RS16900	COG0840	transmembrane signaling receptor activity
CCY86_RS16920	COG2070	2-Nitropropane dioxygenase
CCY86_RS16930	COG1695	Transcriptional regulator
CCY86_RS16945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCY86_RS16955	COG0745	RESPONSE REGULATOR receiver
CCY86_RS16960	COG2205	protein histidine kinase activity
CCY86_RS16975	COG0589	response to stress
CCY86_RS16995	COG0789	Transcriptional regulator
CCY86_RS17005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCY86_RS17030	COG1764	response to oxidative stress
CCY86_RS17040	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CCY86_RS17065	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCY86_RS17070	COG2188	Transcriptional regulator
CCY86_RS17075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS17080	COG2197	response regulator
CCY86_RS17100	COG1815	bacterial-type flagellum-dependent cell motility
CCY86_RS17110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CCY86_RS17115	COG1749	Flagellar hook protein flgE
CCY86_RS17120	COG4787	bacterial-type flagellum-dependent cell motility
CCY86_RS17130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CCY86_RS17135	COG1706	bacterial-type flagellum-dependent cell motility
CCY86_RS17145	COG1256	bacterial-type flagellum assembly
CCY86_RS17185	COG1987	bacterial-type flagellum assembly
CCY86_RS17190	COG1338	Plays a role in the flagellum-specific transport system
CCY86_RS17220	COG2197	response regulator
CCY86_RS17245	COG1846	Transcriptional regulator
CCY86_RS17260	COG1677	Flagellar hook-basal body complex protein FliE
CCY86_RS17270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCY86_RS17280	COG1157	protein secretion by the type III secretion system
CCY86_RS17300	COG2203	Gaf domain
CCY86_RS17300	COG5001	Diguanylate cyclase
CCY86_RS17300	COG4251	negative regulation of phosphorylation
CCY86_RS17300	COG3706	GGDEF domain
CCY86_RS17315	COG5001	Diguanylate cyclase
CCY86_RS17315	COG3706	GGDEF domain
CCY86_RS17315	COG2203	Gaf domain
CCY86_RS17315	COG4251	negative regulation of phosphorylation
CCY86_RS17335	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS17390	COG2223	nitrite transmembrane transporter activity
CCY86_RS17400	COG4774	siderophore transport
CCY86_RS17420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCY86_RS17425	COG2423	ornithine cyclodeaminase activity
CCY86_RS17430	COG4264	IucA IucC family
CCY86_RS17435	COG2814	Major facilitator Superfamily
CCY86_RS17440	COG4264	IucA IucC family
CCY86_RS17445	COG4264	IucA IucC family
CCY86_RS17455	COG0019	diaminopimelate decarboxylase activity
CCY86_RS17515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCY86_RS17545	COG0456	acetyltransferase
CCY86_RS17545	COG1214	PFAM Peptidase M22, glycoprotease
CCY86_RS17575	COG1942	4-Oxalocrotonate Tautomerase
CCY86_RS17615	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCY86_RS17620	COG2814	Major facilitator Superfamily
CCY86_RS17625	COG0667	Aldo Keto reductase
CCY86_RS17640	COG0730	response to heat
CCY86_RS17665	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CCY86_RS17680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCY86_RS17705	COG1607	acyl-coa hydrolase
CCY86_RS17725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCY86_RS17735	COG0765	amino acid transport
CCY86_RS17740	COG0765	amino acid transport
CCY86_RS17745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS17790	COG1846	Transcriptional regulator
CCY86_RS17795	COG1024	Enoyl-CoA hydratase
CCY86_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS17835	COG0657	acetylesterase activity
CCY86_RS17840	COG2226	methyltransferase
CCY86_RS17850	COG2814	Major facilitator Superfamily
CCY86_RS17860	COG1640	4-alpha-glucanotransferase
CCY86_RS17865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCY86_RS17875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCY86_RS17880	COG0366	Alpha amylase catalytic
CCY86_RS17885	COG0366	Alpha amylase catalytic
CCY86_RS17890	COG0297	glycogen (starch) synthase activity
CCY86_RS17900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCY86_RS17905	COG4558	Periplasmic binding protein
CCY86_RS17910	COG3720	iron ion transport
CCY86_RS17915	COG4771	TonB-dependent receptor
CCY86_RS17925	COG3634	alkyl hydroperoxide reductase activity
CCY86_RS17930	COG0735	belongs to the Fur family
CCY86_RS17950	COG1918	ferrous iron import across plasma membrane
CCY86_RS17950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CCY86_RS17960	COG3447	MASE1 domain protein
CCY86_RS17960	COG5001	Diguanylate cyclase
CCY86_RS17960	COG5002	protein histidine kinase activity
CCY86_RS17970	COG0840	transmembrane signaling receptor activity
CCY86_RS17990	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CCY86_RS18005	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CCY86_RS18025	COG0688	phosphatidylethanolamine metabolic process
CCY86_RS18030	COG2814	Major facilitator Superfamily
CCY86_RS18050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCY86_RS18060	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS18130	COG2824	Alkylphosphonate utilization operon protein PhnA
CCY86_RS18135	COG5298	Protein conserved in bacteria
CCY86_RS18170	COG3064	Membrane
CCY86_RS18170	COG3210	domain, Protein
CCY86_RS18170	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CCY86_RS18185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCY86_RS18205	COG1113	amino acid transport
CCY86_RS18220	COG0644	oxidoreductase
CCY86_RS18250	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
CCY86_RS18275	COG5001	Diguanylate cyclase
CCY86_RS18275	COG3300	MHYT domain
CCY86_RS18330	COG0583	DNA-binding transcription factor activity
CCY86_RS18370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCY86_RS18380	COG2188	Transcriptional regulator
CCY86_RS18385	COG0826	peptidase U32
CCY86_RS18390	COG0826	peptidase U32
CCY86_RS18395	COG3154	lipid carrier protein
CCY86_RS18405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCY86_RS18425	COG2223	nitrite transmembrane transporter activity
CCY86_RS18435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CCY86_RS18440	COG1140	nitrate reductase beta subunit
CCY86_RS18445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CCY86_RS18450	COG2181	nitrate reductase activity
CCY86_RS18455	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCY86_RS18460	COG3850	Histidine kinase
CCY86_RS18465	COG2197	response regulator
CCY86_RS18470	COG0204	Acyl-transferase
CCY86_RS18505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCY86_RS18505	COG4651	solute:proton antiporter activity
CCY86_RS18520	COG2192	nodulation
CCY86_RS18540	COG0151	Belongs to the GarS family
CCY86_RS18550	COG2267	carboxylic ester hydrolase activity
CCY86_RS18560	COG2885	chlorophyll binding
CCY86_RS18575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCY86_RS18600	COG0583	DNA-binding transcription factor activity
CCY86_RS18610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCY86_RS18665	COG3209	COG3209 Rhs family protein
CCY86_RS18695	COG1126	abc transporter atp-binding protein
CCY86_RS18700	COG0765	amino acid transport
CCY86_RS18705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS18710	COG1522	sequence-specific DNA binding
CCY86_RS18715	COG2423	ornithine cyclodeaminase activity
CCY86_RS18740	COG0402	S-adenosylhomocysteine deaminase activity
CCY86_RS18745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCY86_RS18800	COG0537	adenosine 5'-monophosphoramidase activity
CCY86_RS18810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCY86_RS18820	COG0840	transmembrane signaling receptor activity
CCY86_RS18835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCY86_RS18855	COG0668	transmembrane transport
CCY86_RS18890	COG3706	GGDEF domain
CCY86_RS18895	COG1914	H( )-stimulated, divalent metal cation uptake system
CCY86_RS18900	COG0443	Heat shock 70 kDa protein
CCY86_RS18920	COG2910	NAD(P)H-binding
CCY86_RS18990	COG1459	type II secretion system
CCY86_RS19010	COG2165	general secretion pathway protein
CCY86_RS19050	COG1404	Belongs to the peptidase S8 family
CCY86_RS19055	COG3396	Phenylacetate-CoA oxygenase
CCY86_RS19060	COG3460	Phenylacetate-CoA oxygenase
CCY86_RS19065	COG3396	Phenylacetate-CoA oxygenase
CCY86_RS19070	COG2151	metal-sulfur cluster biosynthetic enzyme
CCY86_RS19075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCY86_RS19130	COG1733	regulation of RNA biosynthetic process
CCY86_RS19160	COG0778	Nitroreductase
CCY86_RS19165	COG1797	cobyrinic acid a,c-diamide synthase activity
CCY86_RS19200	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CCY86_RS19205	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CCY86_RS19210	COG1648	precorrin-2 dehydrogenase activity
CCY86_RS19210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCY86_RS19225	COG3411	Ferredoxin
CCY86_RS19230	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CCY86_RS19235	COG1126	abc transporter atp-binding protein
CCY86_RS19240	COG0765	amino acid transport
CCY86_RS19245	COG4597	amino acid ABC transporter
CCY86_RS19250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS19260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CCY86_RS19275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CCY86_RS19280	COG3251	PFAM MbtH domain protein
CCY86_RS19310	COG1522	sequence-specific DNA binding
CCY86_RS19315	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CCY86_RS19320	COG1024	Enoyl-CoA hydratase
CCY86_RS19325	COG1024	Enoyl-CoA hydratase
CCY86_RS19340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCY86_RS19345	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS19370	COG2814	Major facilitator Superfamily
CCY86_RS19385	COG0519	Catalyzes the synthesis of GMP from XMP
CCY86_RS19390	COG2807	transmembrane transport
CCY86_RS19410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS19420	COG1024	Enoyl-CoA hydratase
CCY86_RS19445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCY86_RS19450	COG0583	DNA-binding transcription factor activity
CCY86_RS19455	COG0259	pyridoxamine-phosphate oxidase activity
CCY86_RS19465	COG0134	indole-3-glycerol-phosphate synthase activity
CCY86_RS19470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCY86_RS19505	COG1960	acyl-CoA dehydrogenase activity
CCY86_RS19525	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CCY86_RS19535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCY86_RS19540	COG1690	Belongs to the RtcB family
CCY86_RS19630	COG1858	cytochrome C peroxidase
CCY86_RS19635	COG1730	sister chromatid segregation
CCY86_RS19660	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CCY86_RS19685	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CCY86_RS19825	COG1649	PFAM Uncharacterised BCR, COG1649
CCY86_RS19835	COG2885	chlorophyll binding
CCY86_RS19915	COG0436	Aminotransferase
CCY86_RS19940	COG0587	DNA-directed DNA polymerase activity
CCY86_RS19945	COG3620	sequence-specific DNA binding
CCY86_RS19950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCY86_RS19965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCY86_RS19980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCY86_RS19995	COG3842	ATPase activity
CCY86_RS20010	COG1840	ABC-type Fe3 transport system, periplasmic component
CCY86_RS20020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCY86_RS20025	COG4206	TonB-dependent receptor
CCY86_RS20045	COG0579	oxidoreductase
CCY86_RS20070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCY86_RS20080	COG0697	spore germination
CCY86_RS20095	COG0583	DNA-binding transcription factor activity
CCY86_RS20100	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCY86_RS20110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCY86_RS20115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS20125	COG2271	Major facilitator Superfamily
CCY86_RS20135	COG2721	sulfolactate sulfo-lyase activity
CCY86_RS20140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCY86_RS20155	COG2271	Major facilitator Superfamily
CCY86_RS20160	COG1051	belongs to the nudix hydrolase family
CCY86_RS20160	COG1056	cytidyltransferase-related domain
CCY86_RS20190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CCY86_RS20235	COG1595	DNA-templated transcription, initiation
CCY86_RS20245	COG2197	response regulator
CCY86_RS20250	COG0745	RESPONSE REGULATOR receiver
CCY86_RS20290	COG4790	Type iii secretion
CCY86_RS20305	COG4789	Type iii secretion
CCY86_RS20310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCY86_RS20355	COG2207	Transcriptional regulator
CCY86_RS20360	COG1450	Type ii and iii secretion system protein
CCY86_RS20365	COG4886	Leucine-rich repeat (LRR) protein
CCY86_RS20450	COG1674	ftsk spoiiie
CCY86_RS20465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCY86_RS20475	COG1396	sequence-specific DNA binding
CCY86_RS20495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS20515	COG1063	alcohol dehydrogenase
CCY86_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS20525	COG3265	gluconokinase activity
CCY86_RS20535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCY86_RS20540	COG0436	Aminotransferase
CCY86_RS20550	COG0511	ligase activity, forming carbon-carbon bonds
CCY86_RS20560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCY86_RS20565	COG1984	allophanate hydrolase subunit 2
CCY86_RS20575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCY86_RS20580	COG4221	oxidoreductase activity
CCY86_RS20585	COG0765	amino acid transport
CCY86_RS20590	COG0765	amino acid transport
CCY86_RS20595	COG1126	abc transporter atp-binding protein
CCY86_RS20600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS20610	COG1882	Formate acetyltransferase
CCY86_RS20630	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCY86_RS20645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCY86_RS20650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCY86_RS20755	COG0038	chloride channel
CCY86_RS20760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCY86_RS20800	COG0318	PFAM AMP-dependent synthetase and ligase
CCY86_RS20835	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CCY86_RS20835	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CCY86_RS20840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCY86_RS20885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCY86_RS20895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCY86_RS20915	COG0110	maltose O-acetyltransferase activity
CCY86_RS21000	COG1132	(ABC) transporter
CCY86_RS21010	COG4771	TonB-dependent receptor
CCY86_RS21025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCY86_RS21025	COG2226	methyltransferase
CCY86_RS21025	COG3433	isochorismatase activity
CCY86_RS21050	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCY86_RS21060	COG0840	transmembrane signaling receptor activity
CCY86_RS21090	COG0473	3-isopropylmalate dehydrogenase activity
CCY86_RS21100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCY86_RS21105	COG0601	transmembrane transport
CCY86_RS21110	COG0747	negative chemotaxis
CCY86_RS21115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS21125	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS21135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCY86_RS21145	COG1522	sequence-specific DNA binding
CCY86_RS21180	COG1473	amidohydrolase
CCY86_RS21210	COG0583	DNA-binding transcription factor activity
CCY86_RS21225	COG3220	belongs to the UPF0276 family
CCY86_RS21275	COG2223	nitrite transmembrane transporter activity
CCY86_RS21280	COG0243	molybdopterin cofactor binding
CCY86_RS21290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CCY86_RS21295	COG5001	Diguanylate cyclase
CCY86_RS21295	COG3300	MHYT domain
CCY86_RS21300	COG3158	transport of potassium into the cell
CCY86_RS21305	COG1278	Cold shock
CCY86_RS21320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCY86_RS21335	COG4689	acetoacetate decarboxylase
CCY86_RS21340	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS21365	COG0673	inositol 2-dehydrogenase activity
CCY86_RS21375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCY86_RS21395	COG1621	beta-fructofuranosidase activity
CCY86_RS21405	COG1609	Transcriptional regulator
CCY86_RS21490	COG3210	domain, Protein
CCY86_RS21500	COG2831	hemolysin activation secretion protein
CCY86_RS21510	COG2124	cytochrome p450
CCY86_RS21520	COG0673	inositol 2-dehydrogenase activity
CCY86_RS21575	COG4964	Belongs to the GSP D family
CCY86_RS21615	COG2197	response regulator
CCY86_RS21650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCY86_RS21655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCY86_RS21660	COG1877	trehalose-phosphatase activity
CCY86_RS21670	COG1846	Transcriptional regulator
CCY86_RS21675	COG1764	response to oxidative stress
CCY86_RS21690	COG2951	lytic endotransglycosylase activity
CCY86_RS21695	COG0583	DNA-binding transcription factor activity
CCY86_RS21700	COG0657	acetylesterase activity
CCY86_RS21705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS21720	COG1279	arginine transmembrane transporter activity
CCY86_RS21725	COG0583	DNA-binding transcription factor activity
CCY86_RS21740	COG2197	response regulator
CCY86_RS21750	COG2066	Belongs to the glutaminase family
CCY86_RS21755	COG4149	molybdate abc transporter
CCY86_RS21760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCY86_RS21800	COG3813	Protein conserved in bacteria
CCY86_RS21820	COG0745	RESPONSE REGULATOR receiver
CCY86_RS21825	COG2205	protein histidine kinase activity
CCY86_RS21850	COG1253	flavin adenine dinucleotide binding
CCY86_RS21855	COG1858	cytochrome C peroxidase
CCY86_RS21860	COG3511	phospholipase C
CCY86_RS21895	COG2205	protein histidine kinase activity
CCY86_RS21895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS21935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CCY86_RS21940	COG0251	oxidation-reduction process
CCY86_RS21950	COG0800	Aldolase
CCY86_RS21955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCY86_RS21960	COG2197	response regulator
CCY86_RS21965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCY86_RS21990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCY86_RS21995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCY86_RS22035	COG1294	oxidase, subunit
CCY86_RS22040	COG1271	oxidase subunit
CCY86_RS22045	COG5001	Diguanylate cyclase
CCY86_RS22045	COG3300	MHYT domain
CCY86_RS22050	COG0840	transmembrane signaling receptor activity
CCY86_RS22060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCY86_RS22075	COG0438	transferase activity, transferring glycosyl groups
CCY86_RS22080	COG0534	Mate efflux family protein
CCY86_RS22135	COG0243	molybdopterin cofactor binding
CCY86_RS22140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCY86_RS22150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCY86_RS22160	COG0840	transmembrane signaling receptor activity
CCY86_RS22175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCY86_RS22190	COG2267	carboxylic ester hydrolase activity
CCY86_RS22210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCY86_RS22215	COG0436	Aminotransferase
CCY86_RS22220	COG0473	3-isopropylmalate dehydrogenase activity
CCY86_RS22220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCY86_RS22250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCY86_RS22255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCY86_RS22270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCY86_RS22275	COG1454	alcohol dehydrogenase
CCY86_RS22280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCY86_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
CCY86_RS22325	COG0477	Major facilitator Superfamily
CCY86_RS22330	COG0114	fumarate hydratase activity
CCY86_RS22365	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CCY86_RS22385	COG3766	membrane
CCY86_RS22390	COG0683	leucine binding
CCY86_RS22415	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCY86_RS22490	COG1522	sequence-specific DNA binding
CCY86_RS22520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCY86_RS22555	COG3278	Belongs to the heme-copper respiratory oxidase family
CCY86_RS22565	COG0596	Alpha beta hydrolase
CCY86_RS22605	COG1271	oxidase subunit
CCY86_RS22610	COG1294	oxidase, subunit
CCY86_RS22615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCY86_RS22625	COG0251	oxidation-reduction process
CCY86_RS22660	COG3550	peptidyl-serine autophosphorylation
CCY86_RS22680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCY86_RS22700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCY86_RS22705	COG0730	response to heat
CCY86_RS22710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCY86_RS22720	COG0583	DNA-binding transcription factor activity
CCY86_RS22725	COG0730	response to heat
CCY86_RS22755	COG0668	transmembrane transport
CCY86_RS22760	COG1742	UPF0060 membrane protein
CCY86_RS22830	COG0352	thiamine-phosphate diphosphorylase activity
CCY86_RS22835	COG0477	Major facilitator Superfamily
CCY86_RS22840	COG1454	alcohol dehydrogenase
CCY86_RS22845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCY86_RS22850	COG0642	Histidine kinase
CCY86_RS22865	COG0837	glucose binding
CCY86_RS22865	COG1737	Transcriptional regulator
CCY86_RS22870	COG0837	glucose binding
CCY86_RS22880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CCY86_RS22905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCY86_RS22910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCY86_RS22920	COG1845	cytochrome c oxidase, subunit III
CCY86_RS22955	COG2271	Major facilitator Superfamily
CCY86_RS22965	COG0583	DNA-binding transcription factor activity
CCY86_RS22970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCY86_RS22980	COG0765	amino acid transport
CCY86_RS22985	COG0010	Belongs to the arginase family
CCY86_RS22990	COG2197	response regulator
CCY86_RS23015	COG2022	thiamine diphosphate biosynthetic process
CCY86_RS23015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCY86_RS23020	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS23030	COG0583	DNA-binding transcription factor activity
CCY86_RS23035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS23040	COG2814	Major facilitator Superfamily
CCY86_RS23050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS23115	COG1012	belongs to the aldehyde dehydrogenase family
CCY86_RS23120	COG0473	3-isopropylmalate dehydrogenase activity
CCY86_RS23130	COG2271	Major facilitator Superfamily
CCY86_RS23135	COG2721	sulfolactate sulfo-lyase activity
CCY86_RS23145	COG1475	DNA binding
CCY86_RS23155	COG3969	phosphoadenosine phosphosulfate
CCY86_RS23175	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCY86_RS23180	COG0745	RESPONSE REGULATOR receiver
CCY86_RS23185	COG2201	protein-glutamate methylesterase activity
CCY86_RS23190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCY86_RS23200	COG0840	transmembrane signaling receptor activity
CCY86_RS23205	COG0835	chemotaxis
CCY86_RS23215	COG0745	RESPONSE REGULATOR receiver
CCY86_RS23220	COG1360	Flagellar Motor Protein
CCY86_RS23255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCY86_RS23260	COG3384	dioxygenase
CCY86_RS23270	COG0583	DNA-binding transcription factor activity
CCY86_RS23280	COG2159	amidohydrolase
CCY86_RS23290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCY86_RS23300	COG2205	protein histidine kinase activity
CCY86_RS23320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCY86_RS23340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCY86_RS23345	COG2831	hemolysin activation secretion protein
CCY86_RS23350	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CCY86_RS23350	COG3210	domain, Protein
CCY86_RS23350	COG3064	Membrane
CCY86_RS23435	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCY86_RS23605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CCY86_RS23675	COG0697	spore germination
CCY86_RS23680	COG0583	DNA-binding transcription factor activity
CCY86_RS23705	COG5297	Belongs to the glycosyl hydrolase family 6
CCY86_RS23760	COG1104	cysteine desulfurase activity
CCY86_RS23785	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CCY86_RS23795	COG4213	ABC transporter substrate-binding protein
CCY86_RS23800	COG1129	ABC transporter
CCY86_RS23805	COG4214	carbohydrate transport
CCY86_RS23810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCY86_RS23815	COG1609	Transcriptional regulator
CCY86_RS23835	COG0300	oxidoreductase activity
CCY86_RS23845	COG0583	DNA-binding transcription factor activity
CCY86_RS23875	COG1968	undecaprenyl-diphosphatase activity
CCY86_RS23890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCY86_RS23940	COG4977	sequence-specific DNA binding
CCY86_RS23995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCY86_RS24020	COG5487	UPF0391 membrane protein
CCY86_RS24025	COG2204	response regulator
CCY86_RS24040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CCY86_RS24060	COG2205	protein histidine kinase activity
CCY86_RS24070	COG2252	PERMEase